Xenobiotica, Volume 45, Issue 5 (2015)

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Xenobiotica, Volume 45, Issue 5 (2015)

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Research Article

Article
IFN-γ regulates cytochrome 3A29 through pregnane X receptor in pigs
Xiaowen Li, Xiuzhong Hu, Xiue Jin, Xiaoqiao Zhou, Xiliang Wang, Deshi Shi & Dingren Bi
Pages: 373-379
Published online: 21 Nov 2014
AbstractforIFN-γ regulates cytochrome 3A29 through pregnane X receptor in pigs | Full Text | References | PDF (655.2 KB)
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Article
Evaluation of change in the skin concentration of tazarotene and betamethasone dipropionate based on drug–drug interaction for transdermal drug delivery in miniature pig
Biao Yu, Pengcheng Ma, Linwen Yuan, Dingding Chen & Jin Yang
Pages: 380-384
Published online: 20 Nov 2014
AbstractforEvaluation of change in the skin concentration of tazarotene and betamethasone dipropionate based on drug–drug interaction for transdermal drug delivery in miniature pig | Full Text | References | PDF (271.9 KB)
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Article
Stereoselective oxidation metabolism of 20(S)-protopanaxatriol in human liver microsomes and in rats
Wenyan Wang, Yingying Ni, Li Wang, Xin Che, Wanhui Liu & Qingguo Meng
Pages: 385-395
Published online: 28 Nov 2014
AbstractforStereoselective oxidation metabolism of 20(S)-protopanaxatriol in human liver microsomes and in rats | Full Text | References | PDF (1.1 MB)
  • 190 Views
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Article
An in vitro approach to investigate ocular metabolism of a topical, selective β1-adrenergic blocking agent, betaxolol
Jennifer L. Bushee, Christine E. Dunne & Upendra A. Argikar
Pages: 396-405
Published online: 05 Dec 2014
AbstractforAn in vitro approach to investigate ocular metabolism of a topical, selective β1-adrenergic blocking agent, betaxolol | Full Text | References | PDF (903.6 KB) | Supplemental
  • 368 Views
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Article
Inhibitory effect of six herbal extracts on CYP2C8 enzyme activity in human liver microsomes
Ahmed A. Albassam, Mohamed-Eslam F. Mohamed & Reginald F. Frye
Pages: 406-412
Published online: 28 Nov 2014
AbstractforInhibitory effect of six herbal extracts on CYP2C8 enzyme activity in human liver microsomes | Full Text | References | PDF (352.1 KB)
  • 460 Views
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Article
Metronidazole reduces the expression of cytochrome P450 enzymes in HepaRG cells and cryopreserved human hepatocytes
Toshiyuki Kudo, Yumiko Endo, Rina Taguchi, Masami Yatsu & Kiyomi Ito
Pages: 413-419
Published online: 03 Dec 2014
AbstractforMetronidazole reduces the expression of cytochrome P450 enzymes in HepaRG cells and cryopreserved human hepatocytes | Full Text | References | PDF (507.1 KB)
  • 554 Views
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Article
Development of QTc prolongation model incorporating circadian rhythm using harmonic model
Hyun-moon Back, Jong-Hwa Lee, Hwi-yeol Yun & Kwang-il Kwon
Pages: 420-427
Published online: 05 Dec 2014
AbstractforDevelopment of QTc prolongation model incorporating circadian rhythm using harmonic model | Full Text | References | PDF (1 MB)
  • 287 Views
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Article
Metabolism and disposition of a potent and selective JNK inhibitor [14C]tanzisertib following oral administration to rats, dogs and humans
Christian Atsriku, Matthew Hoffmann, Ying Ye, Gondi Kumar & Sekhar Surapaneni
Pages: 428-441
Published online: 08 Dec 2014
AbstractforMetabolism and disposition of a potent and selective JNK inhibitor [14C]tanzisertib following oral administration to rats, dogs and humans | Full Text | References | PDF (938.9 KB)
  • 350 Views
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Article
The role of the c-Jun N-terminal kinases 1/2 and receptor-interacting protein kinase 3 in furosemide-induced liver injury
Mitchell R. McGill, Kuo Du, Yuchao Xie, Mary Lynn Bajt, Wen-Xing Ding & Hartmut Jaeschke
Pages: 442-449
Published online: 25 Nov 2014
AbstractforThe role of the c-Jun N-terminal kinases 1/2 and receptor-interacting protein kinase 3 in furosemide-induced liver injury | Full Text | References | PDF (1.6 MB)
  • 283 Views
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Article
Toxicokinetics and tissue distribution of prothioconazole in male adult Sprague-Dawley rats following a single oral administration
Feng Zhou, Lingling Dai, Sihua Wei, Guihong Cheng & Long Li
Pages: 450-455
Published online: 03 Dec 2014
AbstractforToxicokinetics and tissue distribution of prothioconazole in male adult Sprague-Dawley rats following a single oral administration | Full Text | References | PDF (177.5 KB)
  • 194 Views
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Article
Gender differences in corydaline pharmacokinetics in rats
Ji Won Jung, Mi Ran Choi, Yong Sam Kwon, Jin Seok Jeong, Miwon Son & Hee Eun Kang
Pages: 456-463
Published online: 28 Nov 2014
AbstractforGender differences in corydaline pharmacokinetics in rats | Full Text | References | PDF (288.9 KB)
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Corrigendum

Correction
Corrigendum
Page: 464
Published online: 05 Jun 2015
CitationforCorrigendum | Full Text | PDF (48.5 KB)
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