Cancer Biology & Therapy, Volume 10, Issue 8 (2010)

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Cancer Biology & Therapy, Volume 10, Issue 8 (2010)

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Review

Review Article
Ubiquitin becomes ubiquitous in cancer
Emerging roles of ubiquitin ligases and deubiquitinases in tumorigenesis and as therapeutic targets
Dingding Shi & Steven R. Grossman
Pages: 737-747
Published online: 15 Oct 2010
AbstractforUbiquitin becomes ubiquitous in cancer | Full Text | References | PDF (1 MB)
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Clinical Study

Article
MicroRNA miR-17-5p is overexpressed in pancreatic cancer, associated with a poor prognosis, and involved in cancer cell proliferation and invasion
Jun Yu, Kenoki Ohuchida, Kazuhiro Mizumoto, Hayato Fujita, Kouhei Nakata & Masao Tanaka
Pages: 748-757
Published online: 15 Oct 2010
AbstractforMicroRNA miR-17-5p is overexpressed in pancreatic cancer, associated with a poor prognosis, and involved in cancer cell proliferation and invasion | PDF (1.6 MB)
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Research Paper

Article
Analysis of steroid hormone effects on xenografted human NF1 tumor schwann cells
Hua Li, Xuelian Zhang, Lauren Fishbein, Frederick Kweh, Martha Campbell-Thompson, George Q. Perrin, David Muir & Margaret Wallace
Pages: 758-764
Published online: 15 Oct 2010
AbstractforAnalysis of steroid hormone effects on xenografted human NF1 tumor schwann cells | Full Text | References | PDF (1.3 MB)
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Commentary

Steroid hormones drive cancer development
SubbaRao V. Madhunapantula, Paul Mosca & Gavin P. Robertson
Pages: 765-766
Published online: 15 Oct 2010
Abstractfor Steroid hormones drive cancer development | PDF (163.2 KB)
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Research Paper

Article
A preclinical 188Re tumor therapeutic investigation using MORF/cMORF pretargeting and an antiTAG-72 antibody CC49
Guozheng Liu, Shuping Dou, Stephen Baker, Ali Akalin, Dengfeng Cheng, Ling Chen, Mary Rusckowski & Donald J. Hnatowich
Pages: 767-774
Published online: 15 Oct 2010
AbstractforA preclinical 188Re tumor therapeutic investigation using MORF/cMORF pretargeting and an antiTAG-72 antibody CC49 | Full Text | References | PDF (1.5 MB)
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Commentary

Pretargeting the masses: A means of improving and mainstreaming targeted molecular delivery?
Van Nguyen, Jesse Marie Conyers & Akiva Mintz
Pages: 775-779
Published online: 15 Oct 2010
Abstractfor Pretargeting the masses: A means of improving and mainstreaming targeted molecular delivery? | PDF (858.2 KB)
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Research Paper

Article
15-Hydroxyprostaglandin dehydrogenase is a tumor suppressor of human gastric cancer
Zhenxiong Liu, Xin Wang, Yuanyuan Lu, Rui Du, Guanhong Luo, Jun Wang, Huihong Zhai, Faming Zhang, Qinsheng Wen, Kaichun Wu & Daiming Fan
Pages: 780-787
Published online: 15 Oct 2010
Abstractfor15-Hydroxyprostaglandin dehydrogenase is a tumor suppressor of human gastric cancer | PDF (9 MB)
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Article
Overexpression of EZH2 contributes to acquired cisplatin resistance in ovarian cancer cells in vitro and in vivo
Sha Hu, Lili Yu, Zhimin Li, Yi Shen, Jing Wang, Jing Cai, Lan Xiao & Zehua Wang
Pages: 788-795
Published online: 15 Oct 2010
AbstractforOverexpression of EZH2 contributes to acquired cisplatin resistance in ovarian cancer cells in vitro and in vivo | PDF (1.4 MB)
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Article
SILAC-based quantitative proteomic approach to identify potential biomarkers from the esophageal squamous cell carcinoma secretome
Manoj Kumar Kashyap, H. C. Harsha, Santosh Renuse, Harsh Pawar, Nandini A. Sahasrabuddhe, Min-Sik Kim, Arivusudar Marimuthu, Shivakumar Keerthikumar, Babylakshmi Muthusamy, Kumaran Kandasamy, Yashwanth Subbannayya, Thottethodi Subrahmanya Keshava Prasad, Riaz Mahmood, Raghothama Chaerkady, Stephen J. Meltzer, Rekha V. Kumar, Anil K. Rustgi & Akhilesh Pandey
Pages: 796-810
Published online: 15 Oct 2010
AbstractforSILAC-based quantitative proteomic approach to identify potential biomarkers from the esophageal squamous cell carcinoma secretome | Full Text | References | PDF (3.9 MB) | Supplemental
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Commentary

Maximizing early detection of esophageal squamous cell carcinoma via SILAC-proteomics
Kevin K. Lee, Kristina Todorova & Anna Mandinova
Pages: 811-813
Published online: 15 Oct 2010
Abstractfor Maximizing early detection of esophageal squamous cell carcinoma via SILAC-proteomics | Full Text | References | PDF (391.9 KB)
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Research Paper

Article
Induction of cellular apoptosis in human breast cancer by DLBS1425, a Phaleria macrocarpa compound extract, via down-regulation of PI3-kinase/AKT pathway
Olivia M. Tandrasasmita, Jason S. Lee, Sung Hee Baek & Raymond R. Tjandrawinata
Pages: 814-823
Published online: 15 Oct 2010
AbstractforInduction of cellular apoptosis in human breast cancer by DLBS1425, a Phaleria macrocarpa compound extract, via down-regulation of PI3-kinase/AKT pathway | PDF (2.3 MB)
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