Cancer Biology & Therapy, Volume 4, Issue 12 (2005)

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Cancer Biology & Therapy, Volume 4, Issue 12 (2005)

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Editor's Corner

Editorial
Cover Image
Page: i
Published online: 16 Nov 2005
AbstractforCover Image | PDF (1.2 MB)
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News

News
Mobilizing Preformed Nuclear RNA Under Stress
Page: 1306
Published online: 14 Nov 2005
AbstractforMobilizing Preformed Nuclear RNA Under Stress | PDF (127.6 KB)
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News
Nanoparticles To Deliver Chemotherapy
Page: 1306
Published online: 14 Nov 2005
AbstractforNanoparticles To Deliver Chemotherapy | PDF (127.6 KB)
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News
Residual Body Remains in Older of Two Daughter Cells
Page: 1306
Published online: 14 Nov 2005
AbstractforResidual Body Remains in Older of Two Daughter Cells | PDF (127.6 KB)
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News
MetAP2, A New Therapeutic Target in the NF1 Pathway
Page: 1306
Published online: 14 Nov 2005
AbstractforMetAP2, A New Therapeutic Target in the NF1 Pathway | PDF (127.6 KB)
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News
CBP Loss Confers Risk of Aggressive Form of Breast Cancer
Page: 1306
Published online: 14 Nov 2005
AbstractforCBP Loss Confers Risk of Aggressive Form of Breast Cancer | PDF (127.6 KB)
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News
EGFRvIII and PTEN Predict Response to EGFR Blockade in Glioblastoma
Page: 1306
Published online: 14 Nov 2005
AbstractforEGFRvIII and PTEN Predict Response to EGFR Blockade in Glioblastoma | PDF (127.6 KB)
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News
Are Some Tumors Really Addicted to Ras?
Page: 1306
Published online: 15 Nov 2005
AbstractforAre Some Tumors Really Addicted to Ras? | PDF (127.6 KB)
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News
Improving Survival of Pancreatic Cancer Patients with a Therapeutic Vaccine
Page: 1306
Published online: 15 Nov 2005
AbstractforImproving Survival of Pancreatic Cancer Patients with a Therapeutic Vaccine | PDF (127.6 KB)
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News
Monitoring the Immune Attack on Cancer with PET Imaging
Page: 1306
Published online: 15 Nov 2005
AbstractforMonitoring the Immune Attack on Cancer with PET Imaging | PDF (127.6 KB)
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Review

Review Article
How avastin potentiates chemotherapeutic drugs: Action and reaction in antiangiogenic therapy
Mikhail V. Blagosklonny
Pages: 1307-1310
Published online: 18 Oct 2005
AbstractforHow avastin potentiates chemotherapeutic drugs: Action and reaction in antiangiogenic therapy | PDF (259.8 KB)
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Clinical Trials

Article
Evaluation of irinotecan plus paclitaxel in patients with advanced non-small cell lung cancer
John R. Murren, Nicolaj Andersen, Diamondo Psyrri, Deborah Brandt, Rajani Nadkarni, Michal Rose, Nicole Parisot, Arthur T. Rosenfield, Giuseppe Pizzorno & Daniel Zelterman
Pages: 1311-1315
Published online: 18 Oct 2005
AbstractforEvaluation of irinotecan plus paclitaxel in patients with advanced non-small cell lung cancer | PDF (223.7 KB)
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Commentary

A slow disengagement from platinum-based chemotherapy for patients with advanced non-small cell lung cancer
Marc S. Ballas & Phillip A. Dennis
Pages: 1316-1317
Published online: 18 Oct 2005
AbstractforA slow disengagement from platinum-based chemotherapy for patients with advanced non-small cell lung cancer | PDF (138.1 KB)
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Clinical Trials

Article
Intralesional targeted alpha therapy for metastatic melanoma
Barry J Allen, Chand Raja, Syed Rizvi, Yong Li, Wendy Tsui, Peter Graham, John Thompson, Ralph Reisfeld, John Kearsley, Alfred Morgenstern & Christos Apostolidis
Pages: 1318-1324
Published online: 18 Oct 2005
AbstractforIntralesional targeted alpha therapy for metastatic melanoma | PDF (478.9 KB)
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Research Paper

Article
Induction of resistance to Aplidin® in a human ovarian cancer cell line related to MDR expression
Gianluca Tognon, Sergio Bernasconi, Nicola Celli, Glynn T. Faircloth, Carmen Cuevas, José M. Jimeno, Eugenio Erba & Maurizio D'Incalci
Pages: 1325-1330
Published online: 18 Oct 2005
AbstractforInduction of resistance to Aplidin® in a human ovarian cancer cell line related to MDR expression | PDF (572.2 KB)
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Article
The maturation of murine bone marrow-derived dendritic cells by tumor lysate uptake in vitro is not essential for cancer immunotherapy
Sung-Chil Woo, Gi-Young Kim, Chang-Min Lee, Dong-Oh Moon, Tae-Hyung Lee, Yu-Seok Moon, Nam-Chul Park, Man-Soo Yoon, Kyu-Sub Lee & Yeong-Min Park
Pages: 1331-1335
Published online: 18 Oct 2005
AbstractforThe maturation of murine bone marrow-derived dendritic cells by tumor lysate uptake in vitro is not essential for cancer immunotherapy | PDF (585.1 KB)
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Article
Expression of osteopontin and HGF/Met in adult soft tissue tumors
Vivien H.C. Bramwell, Alan B. Tuck, Sylvia M. Wilson, Larry W. Stitt, Anil K. Cherian, Stewart C. Rorke, Waleed Al-Katib, Carl O. Postenko, Carl O. Postenko & Ann F. Chambers
Pages: 1336-1341
Published online: 18 Oct 2005
AbstractforExpression of osteopontin and HGF/Met in adult soft tissue tumors | PDF (380.8 KB)
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Article
Expression of delayed rectifier potassium channels and their possible roles in proliferation of human gastric cancer cells
Mei Lan, Yongquan Shi, Zheyi Han, Zhiming Hao, Yanglin Pan, Na Liu, Changcun Guo, Liu Hong, Jun Wang, Taidong Qiao & Daiming Fan
Pages: 1342-1347
Published online: 18 Oct 2005
AbstractforExpression of delayed rectifier potassium channels and their possible roles in proliferation of human gastric cancer cells | PDF (528.2 KB)
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Article
Adenovirus-mediated Ink4a/ARF gene transfer significantly suppressed the growth of pancreatic carcinoma cells
Fang Chen, Yitting Li, Zhaohui Lu, Jie Gao & Jie Chen
Pages: 1348-1354
Published online: 18 Oct 2005
AbstractforAdenovirus-mediated Ink4a/ARF gene transfer significantly suppressed the growth of pancreatic carcinoma cells | PDF (728.3 KB)
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Article
RNA interference targeting of A1 receptor-overexpressing breast carcinoma cells leads to diminished rates of cell proliferation and induction of apoptosis
Asra Mirza, Andrea Basso, Stuart Black, Michael Malkowski, Lia Kwee, Jonathan A. Patcher, Jean E. Lachowicz, Yan Wang & Suxing Liu
Pages: 1355-1360
Published online: 18 Oct 2005
AbstractforRNA interference targeting of A1 receptor-overexpressing breast carcinoma cells leads to diminished rates of cell proliferation and induction of apoptosis | PDF (451.2 KB)
  • 549 Views
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Article
Wnt signaling can repress thrombospondin-1 expression in colonic tumorigenesis
Won-Seok Jo, Yusuke Mizukami, Eva-Maria Duerr, Lawrence R. Zukerberg & Daniel C. Chung
Pages: 1361-1366
Published online: 18 Oct 2005
AbstractforWnt signaling can repress thrombospondin-1 expression in colonic tumorigenesis | PDF (475.8 KB)
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Article
Cross talk between mitochondria and superoxide generating NADPH oxidase in breast and ovarian tumors
Mohamed Mokhtar Desouki, Mariola Kulawiec, Sanjay Bansal, Gokul C. Das & Keshav K. Singh
Pages: 1367-1373
Published online: 18 Oct 2005
AbstractforCross talk between mitochondria and superoxide generating NADPH oxidase in breast and ovarian tumors | PDF (1.1 MB)
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Article
Isolating human antibody against human hepatocellular carcinoma by guided-selection
Gup-qiang Bao, Yu Li, Qing-Jiu Ma, Xian-Li He, Jin-Liang Xing, Xiang-Min Yang & Zhi-Nan Chen
Pages: 1374-1380
Published online: 18 Oct 2005
AbstractforIsolating human antibody against human hepatocellular carcinoma by guided-selection | PDF (668.9 KB)
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Article
Assessment of epidermal growth factor receptor (EGFR) signaling in paired colorectal cancer and normal colon tissue samples using computer-aided immunohistochemical analysis
Wells Messersmith, Darin Oppenheimer, Josep Peralba, Valeria Sebastiani, Maria Amador, Antonio Jimeno, Erlinda E. Embuscado, Manuel Hidalgo & Christine A. Iacobuzio-Donahue
Pages: 1381-1386
Published online: 18 Oct 2005
AbstractforAssessment of epidermal growth factor receptor (EGFR) signaling in paired colorectal cancer and normal colon tissue samples using computer-aided immunohistochemical analysis | PDF (510.8 KB)
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Commentary

Hitting the target: Measuring EGFR response to tyrosine kinase inhibitors
Mukesh K. Nyati & Theodore S. Lawrence
Pages: 1387-1388
Published online: 18 Oct 2005
AbstractforHitting the target: Measuring EGFR response to tyrosine kinase inhibitors | PDF (137.4 KB)
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Research Paper

Article
p16Ink4a inhibits histologic progression and angiogenic signaling in min colon tumors
Steven L. Gibson, Amelie Boquoi, Tina Chen, Norman E. Sharpless, Colleen Brensinger & Greg H. Enders
Pages: 1389-1394
Published online: 18 Oct 2005
Abstractforp16Ink4a inhibits histologic progression and angiogenic signaling in min colon tumors | PDF (647 KB)
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Article
Ionizing radiation inhibits tumor neovascularization by inducing ineffective angiogenesis
Jeff H. Tsai, Sosina Makonnen, Michael Feldman, Chandra Sehgal, Amit Maity & William M.F. Lee
Pages: 1395-1400
Published online: 18 Oct 2005
AbstractforIonizing radiation inhibits tumor neovascularization by inducing ineffective angiogenesis | PDF (653.6 KB)
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Article
KLF4 and PCNA identify stages of tumor initiation in a conditional model of cutaneous squamous epithelial neoplasia
Conway C. Huang, Zhaoli Liu, Xingnan Li, Sarah Bailey, Clinton D. Nail, K. Wade Foster, Andra R. Frost, J. Michael Ruppert & Susan M. Lobo-Ruppert
Pages: 1401-1408
Published online: 18 Oct 2005
AbstractforKLF4 and PCNA identify stages of tumor initiation in a conditional model of cutaneous squamous epithelial neoplasia | PDF (1.1 MB)
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Article
Cooperation between BRCA1 and p53 in repair of cyclobutane pyrimidine dimers
Arunasalam Navaraj, Toshio Mori & Wafik S. El-Deiry
Pages: 1409-1414
Published online: 18 Oct 2005
AbstractforCooperation between BRCA1 and p53 in repair of cyclobutane pyrimidine dimers | PDF (897.7 KB)
  • 368 Views
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Commentary

Glucocorticoids and progression of breast cancer
Ingrid Herr & Alexander Marmé
Pages: 1415-1416
Published online: 18 Oct 2005
AbstractforGlucocorticoids and progression of breast cancer | PDF (148.7 KB)
  • 647 Views
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Open Access
Receptor tyrosine kinase mutations: Molecular indicators for therapeutic response or signposts marking important signaling pathways?
Geoffrey W. Krystal
Pages: 1417-1418
Published online: 18 Oct 2005
AbstractforReceptor tyrosine kinase mutations: Molecular indicators for therapeutic response or signposts marking important signaling pathways? | PDF (166.9 KB)
  • 125 Views
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Capitalizing on AKT signaling to inhibit hepatocellular carcinoma cell proliferation
Rajat Singh & Mark J. Czaja
Pages: 1419-1421
Published online: 18 Oct 2005
AbstractforCapitalizing on AKT signaling to inhibit hepatocellular carcinoma cell proliferation | PDF (179.7 KB)
  • 286 Views
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Profiles and Legacies

Editorial
Serendipity, fate, science and leadership
Charis Eng
Pages: 1422-1425
Published online: 18 Oct 2005
AbstractforSerendipity, fate, science and leadership | PDF (609 KB)
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