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Secondary and tertiary sulfonamides: a patent review (2008 – 2012)

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Pages 203-213 | Published online: 14 Nov 2012

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Sefa Celik, Sevim Akyuz & Aysen E. Ozel. (2023) Structural and vibrational investigations and molecular docking studies of a vinca alkoloid, vinorelbine. Journal of Biomolecular Structure and Dynamics 41:19, pages 9666-9685.
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Alessio Nocentini, Andrea Angeli, Fabrizio Carta, Jean-Yves Winum, Raivis Zalubovskis, Simone Carradori, Clemente Capasso, William A. Donald & Claudiu T. Supuran. (2021) Reconsidering anion inhibitors in the general context of drug design studies of modulators of activity of the classical enzyme carbonic anhydrase. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 561-580.
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Linda J. Urbański, Andrea Angeli, Vesa P. Hytönen, Anna Di Fiore, Giuseppina De Simone, Seppo Parkkila & Claudiu T. Supuran. (2021) Inhibition of the β-carbonic anhydrase from the protozoan pathogen Trichomonas vaginalis with sulphonamides. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 330-335.
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Paolo Guglielmi, Giulia Rotondi, Daniela Secci, Andrea Angeli, Paola Chimenti, Alessio Nocentini, Alessandro Bonardi, Paola Gratteri, Simone Carradori & Claudiu T. Supuran. (2020) Novel insights on saccharin- and acesulfame-based carbonic anhydrase inhibitors: design, synthesis, modelling investigations and biological activity evaluation. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1891-1905.
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Alessio Nocentini & Claudiu T. Supuran. (2019) Advances in the structural annotation of human carbonic anhydrases and impact on future drug discovery. Expert Opinion on Drug Discovery 14:11, pages 1175-1197.
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D. I. Ugwuja, U. C. Okoro, S. S. Soman, R. Soni, S. N. Okafor & D. I. Ugwu. (2019) New peptide derived antimalaria and antimicrobial agents bearing sulphonamide moiety. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1388-1399.
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Pavitra S. Thacker, Pirpasha Shaikh, Andrea Angeli, Mohammed Arifuddin & Claudiu T. Supuran. (2019) Synthesis and biological evaluation of novel 8-substituted quinoline-2-carboxamides as carbonic anhydrase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1172-1177.
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Claudiu T. Supuran. (2018) Carbonic anhydrase inhibitors as emerging agents for the treatment and imaging of hypoxic tumors. Expert Opinion on Investigational Drugs 27:12, pages 963-970.
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Claudiu T. Supuran. (2018) Carbonic anhydrase inhibitors and their potential in a range of therapeutic areas. Expert Opinion on Therapeutic Patents 28:10, pages 709-712.
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Claudiu T. Supuran. (2018) Applications of carbonic anhydrases inhibitors in renal and central nervous system diseases. Expert Opinion on Therapeutic Patents 28:10, pages 713-721.
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Claudiu T. Supuran. (2018) Carbon- versus sulphur-based zinc binding groups for carbonic anhydrase inhibitors?. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 485-495.
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Chandra Bhushan Mishra, Shikha Kumari, Andrea Angeli, Simona Maria Monti, Martina Buonanno, Amresh Prakash, Manisha Tiwari & Claudiu T. Supuran. (2016) Design, synthesis and biological evaluation of N-(5-methyl-isoxazol-3-yl/1,3,4-thiadiazol-2-yl)-4-(3-substitutedphenylureido) benzenesulfonamides as human carbonic anhydrase isoenzymes I, II, VII and XII inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 31:sup2, pages 174-179.
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Viviana De Luca, Sonia Del Prete, Daniela Vullo, Vincenzo Carginale, Pietro Di Fonzo, Sameh M Osman, Zeid AlOthman, Claudiu T Supuran & Clemente Capasso. (2016) Expression and characterization of a recombinant psychrophilic γ-carbonic anhydrase (NcoCA) identified in the genome of the Antarctic cyanobacteria belonging to the genus Nostoc. Journal of Enzyme Inhibition and Medicinal Chemistry 31:5, pages 810-817.
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Claudiu T. Supuran. (2016) Carbonic anhydrase inhibition and the management of neuropathic pain. Expert Review of Neurotherapeutics 16:8, pages 961-968.
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Claudiu T. Supuran. (2016) How many carbonic anhydrase inhibition mechanisms exist?. Journal of Enzyme Inhibition and Medicinal Chemistry 31:3, pages 345-360.
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Claudiu T. Supuran. (2016) Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors. Expert Opinion on Drug Metabolism & Toxicology 12:4, pages 423-431.
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Claudiu T Supuran. (2015) Acetazolamide for the treatment of idiopathic intracranial hypertension. Expert Review of Neurotherapeutics 15:8, pages 851-856.
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Yi-Min Liu, Hsiao-Ling Chen, Hsueh-Yun Lee & Jing-Ping Liou. (2014) Tubulin inhibitors: a patent review. Expert Opinion on Therapeutic Patents 24:1, pages 69-88.
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Fabrizio Carta & Claudiu T Supuran. (2013) Diuretics with carbonic anhydrase inhibitory action: a patent and literature review (2005 – 2013). Expert Opinion on Therapeutic Patents 23:6, pages 681-691.
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Truong Giang Luu & Hee‐Kwon Kim. (2023) Visible‐Light‐Driven Sulfonamidation of Arylazo Sulfonesthrough One‐Pot Multicomponent Reaction. Asian Journal of Organic Chemistry.
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Jun Zhang, Feng Zhang, Lifang Lai, Jiang Cheng, Jiangtao Sun & Jie Wu. (2018) Generation of sulfonated 1-isoindolinones through a multicomponent reaction with the insertion of sulfur dioxide. Chemical Communications 54:31, pages 3891-3894.
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Claudiu Supuran. (2017) Special Issue: Sulfonamides. Molecules 22:10, pages 1642.
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Jacob J. Day, Deshka L. Neill, Shi Xu & Ming Xian. (2017) Benzothiazole Sulfinate: A Sulfinic Acid Transfer Reagent under Oxidation-Free Conditions. Organic Letters 19:14, pages 3819-3822.
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Yann Le Duc, Erol Licsandru, Daniela Vullo, Mihail Barboiu & Claudiu T. Supuran. (2017) Carbonic anhydrases activation with 3-amino-1H-1,2,4-triazole-1-carboxamides: Discovery of subnanomolar isoform II activators. Bioorganic & Medicinal Chemistry 25:5, pages 1681-1686.
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Alex S. Deeming, Claire J. Russell & Michael C. Willis. (2014) Combining Organometallic Reagents, the Sulfur Dioxide Surrogate DABSO, and Amines: A One‐Pot Preparation of Sulfonamides, Amenable to Array Synthesis. Angewandte Chemie International Edition 54:4, pages 1168-1171.
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Alex S. Deeming, Claire J. Russell & Michael C. Willis. (2014) Combining Organometallic Reagents, the Sulfur Dioxide Surrogate DABSO, and Amines: A One‐Pot Preparation of Sulfonamides, Amenable to Array Synthesis. Angewandte Chemie 127:4, pages 1184-1187.
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Mariangela Ceruso, Sabrina Antel, Daniela Vullo, Andrea Scozzafava & Claudiu T. Supuran. (2014) Inhibition studies of new ureido-substituted sulfonamides incorporating a GABA moiety against human carbonic anhydrase isoforms I–XIV. Bioorganic & Medicinal Chemistry 22:24, pages 6768-6775.
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Cenzo Congiu, Valentina Onnis, Gianfranco Balboni & Claudiu T. Supuran. (2014) Synthesis and carbonic anhydrase I, II, IX and XII inhibition studies of 4-N,N-disubstituted sulfanilamides incorporating 4,4,4-trifluoro-3-oxo-but-1-enyl, phenacylthiourea and imidazol-2(3H)-one/thione moieties. Bioorganic & Medicinal Chemistry Letters 24:7, pages 1776-1779.
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Amrita K. Saluja, Meena Tiwari, Daniela Vullo & Claudiu T. Supuran. (2014) Substituted benzene sulfonamides incorporating 1,3,5-triazinyl moieties potently inhibit human carbonic anhydrases II, IX and XII. Bioorganic & Medicinal Chemistry Letters 24:5, pages 1310-1314.
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Melissa D’Ascenzio, Simone Carradori, Celeste De Monte, Daniela Secci, Mariangela Ceruso & Claudiu T. Supuran. (2014) Design, synthesis and evaluation of N-substituted saccharin derivatives as selective inhibitors of tumor-associated carbonic anhydrase XII. Bioorganic & Medicinal Chemistry 22:6, pages 1821-1831.
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Jinwu Zhao, Jingxiu Xu, Jiaxi Chen, Xiaoqin Wang & Minghua He. (2014) Metal-free oxidative coupling of amines with sodium sulfinates: a mild access to sulfonamides. RSC Adv. 4:110, pages 64698-64701.
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Daniela Vullo, Sonia Del Prete, Sameh M. Osman, Viviana De Luca, Andrea Scozzafava, Zeid AlOthman, Claudiu T. Supuran & Clemente Capasso. (2014) Sulfonamide inhibition studies of the δ-carbonic anhydrase from the diatom Thalassiosira weissflogii. Bioorganic & Medicinal Chemistry Letters 24:1, pages 275-279.
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Mariangela Ceruso, Daniela Vullo, Andrea Scozzafava & Claudiu T. Supuran. (2013) Inhibition of human carbonic anhydrase isoforms I–XIV with sulfonamides incorporating fluorine and 1,3,5-triazine moieties. Bioorganic & Medicinal Chemistry 21:22, pages 6929-6936.
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Janis Leitans, Agnese Sprudza, Muhammet Tanc, Igor Vozny, Raivis Zalubovskis, Kaspars Tars & Claudiu T. Supuran. (2013) 5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: Solution and X-ray crystallographic studies. Bioorganic & Medicinal Chemistry 21:17, pages 5130-5138.
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Özlen Güzel-Akdemir, Atilla Akdemir, Peiwen Pan, Alane B. Vermelho, Seppo Parkkila, Andrea Scozzafava, Clemente Capasso & Claudiu T. Supuran. (2013) A Class of Sulfonamides with Strong Inhibitory Action against the α-Carbonic Anhydrase from Trypanosoma cruzi . Journal of Medicinal Chemistry 56:14, pages 5773-5781.
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