International Journal of Nanomedicine, Volume 13, Issue (2018)

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International Journal of Nanomedicine, Volume 13, Issue (2018)

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Original Research

Article
Biophysical and biological contributions of polyamine-coated carbon nanotubes and bidimensional buckypapers in the delivery of miRNAs to human cells
Antonella Celluzzi, Alessandro Paolini, Valentina D’Oria, Roberta Risoluti, Stefano Materazzi, Marco Pezzullo, Stefano Casciardi, Simona Sennato, Federico Bordi & Andrea Masotti
Pages: 1-18
Published online: 18 Dec 2017
AbstractforBiophysical and biological contributions of polyamine-coated carbon nanotubes and bidimensional buckypapers in the delivery of miRNAs to human cells | Full Text | References | PDF (4.6 MB)
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Open Access
Article
Enhanced antitumor efficacy of doxorubicin-encapsulated halloysite nanotubes
Kai Li, Yongxing Zhang, Mengting Chen, Yangyang Hu, Weiliang Jiang, Li Zhou, Sisi Li, Min Xu, Qinghua Zhao & Rong Wan
Pages: 19-30
Published online: 19 Dec 2017
AbstractforEnhanced antitumor efficacy of doxorubicin-encapsulated halloysite nanotubes | Full Text | References | PDF (3.6 MB)
  • 78 Views
  • 22 CrossRef citations
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Open Access
Article
Development and characterization of p1025-loaded bioadhesive liquid-crystalline system for the prevention of Streptococcus mutans biofilms
Giovana Maria Fioramonti Calixto, Cristiane Duque, Kelly Limi Aida, Vanessa Rodrigues dos Santos, Loiane Massunari & Marlus Chorilli
Pages: 31-41
Published online: 19 Dec 2017
AbstractforDevelopment and characterization of p1025-loaded bioadhesive liquid-crystalline system for the prevention of Streptococcus mutans biofilms | Full Text | References | PDF (1.2 MB)
  • 103 Views
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Open Access
Article
Double-stranded phosphodiester cytosine-guanine oligodeoxynucleotide complexed with calcium phosphate as a potent vaccine adjuvant for activating cellular and Th1-type humoral immunities
Nobutaka Hanagata, Xianglan Li, Min-Hua Chen, Jie Li & Shinya Hattori
Pages: 43-62
Published online: 20 Dec 2017
AbstractforDouble-stranded phosphodiester cytosine-guanine oligodeoxynucleotide complexed with calcium phosphate as a potent vaccine adjuvant for activating cellular and Th1-type humoral immunities | Full Text | References | PDF (5 MB)
  • 73 Views
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Open Access
Article
Lipopolysaccharide-induced inflammation in monocytes/macrophages is blocked by liposomal delivery of Gi-protein inhibitor
Monica Madalina Tucureanu, Daniela Rebleanu, Cristina Ana Constantinescu, Mariana Deleanu, Geanina Voicu, Elena Butoi, Manuela Calin & Ileana Manduteanu
Pages: 63-76
Published online: 28 Feb 2023
AbstractforLipopolysaccharide-induced inflammation in monocytes/macrophages is blocked by liposomal delivery of Gi-protein inhibitor | Full Text | References | PDF (1.5 MB)
  • 109 Views
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Open Access
Article
Antibacterial activity of trimetal (CuZnFe) oxide nanoparticles
Khalid E Alzahrani, Abdurahman A Niazy, Abdullah M Alswieleh, Rizwan Wahab, Ahmed M El-Toni & Hamdan S Alghamdi
Pages: 77-87
Published online: 20 Dec 2017
AbstractforAntibacterial activity of trimetal (CuZnFe) oxide nanoparticles | Full Text | References | PDF (2.5 MB)
  • 200 Views
  • 28 CrossRef citations
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Open Access
Article
Antibacterial mechanisms of a novel type picosecond laser-generated silver-titanium nanoparticles and their toxicity to human cells
Peri Korshed, Lin Li, Zhu Liu, Aleksandr Mironov & Tao Wang
Pages: 89-101
Published online: 20 Dec 2017
AbstractforAntibacterial mechanisms of a novel type picosecond laser-generated silver-titanium nanoparticles and their toxicity to human cells | Full Text | References | PDF (1.5 MB)
  • 85 Views
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Open Access
Article
Inhibition of cancer cell migration with CuS@ mSiO2-PEG nanoparticles by repressing MMP-2/MMP-9 expression
Guoying Deng, Feng Zhou, Zizheng Wu, Fei Zhang, Kerun Niu, Yingjie Kang, Xijian Liu, Qiugen Wang, Yin Wang & Qian Wang
Pages: 103-116
Published online: 28 Feb 2023
AbstractforInhibition of cancer cell migration with CuS@ mSiO2-PEG nanoparticles by repressing MMP-2/MMP-9 expression | Full Text | References | PDF (7.7 MB)
  • 72 Views
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Open Access
Article
Enhanced bone regeneration using an insulin-loaded nano-hydroxyapatite/collagen/PLGA composite scaffold
Xing Wang, Guilan Zhang, Feng Qi, Yongfeng Cheng, Xuguang Lu, Lu Wang, Jing Zhao & Bin Zhao
Pages: 117-127
Published online: 21 Dec 2017
AbstractforEnhanced bone regeneration using an insulin-loaded nano-hydroxyapatite/collagen/PLGA composite scaffold | Full Text | References | PDF (10.8 MB)
  • 153 Views
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Open Access
Article
Tacrolimus nanoparticles based on chitosan combined with nicotinamide: enhancing percutaneous delivery and treatment efficacy for atopic dermatitis and reducing dose
Kaiyue Yu, Yixuan Wang, Tao Wan, Yuanhao Zhai, Sisi Cao, Wenyi Ruan, Chuanbin Wu & Yuehong Xu
Pages: 129-142
Published online: 22 Dec 2017
AbstractforTacrolimus nanoparticles based on chitosan combined with nicotinamide: enhancing percutaneous delivery and treatment efficacy for atopic dermatitis and reducing dose | Full Text | References | PDF (2.1 MB)
  • 237 Views
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Open Access
Article
Novel functionalized nanoparticles for tumor-targeting co-delivery of doxorubicin and siRNA to enhance cancer therapy
Yu Xia, Tiantian Xu, Changbing Wang, Yinghua Li, Zhengfang Lin, Mingqi Zhao & Bing Zhu
Pages: 143-159
Published online: 28 Feb 2023
AbstractforNovel functionalized nanoparticles for tumor-targeting co-delivery of doxorubicin and siRNA to enhance cancer therapy | Full Text | References | PDF (5.9 MB)
  • 212 Views
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Open Access
Article
Lysyl oxidase activates cancer stromal cells and promotes gastric cancer progression: quantum dot-based identification of biomarkers in cancer stromal cells
Chunwei Peng, Jiuyang Liu, Guifang Yang & Yan Li
Pages: 161-174
Published online: 27 Dec 2017
AbstractforLysyl oxidase activates cancer stromal cells and promotes gastric cancer progression: quantum dot-based identification of biomarkers in cancer stromal cells | Full Text | References | PDF (15.5 MB)
  • 72 Views
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Open Access
Article
Essential oil-loaded lipid nanoparticles for wound healing
Francesca Saporito, Giuseppina Sandri, Maria Cristina Bonferoni, Silvia Rossi, Cinzia Boselli, Antonia Icaro Cornaglia, Barbara Mannucci, Pietro Grisoli, Barbara Vigani & Franca Ferrari
Pages: 175-186
Published online: 27 Dec 2017
AbstractforEssential oil-loaded lipid nanoparticles for wound healing | Full Text | References | PDF (10.7 MB)
  • 1123 Views
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Open Access
Article
Codelivery of doxorubicin and MDR1-siRNA by mesoporous silica nanoparticles-polymerpolyethylenimine to improve oral squamous carcinoma treatment
Dandan Wang, Xiaowei Xu, Kai Zhang, Bin Sun, Lu Wang, Lin Meng, Qilin Liu, Changyu Zheng, Bai Yang & Hongchen Sun
Pages: 187-198
Published online: 28 Dec 2017
AbstractforCodelivery of doxorubicin and MDR1-siRNA by mesoporous silica nanoparticles-polymerpolyethylenimine to improve oral squamous carcinoma treatment | Full Text | References | PDF (7.6 MB)
  • 147 Views
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Open Access
Article
Preparation of anastrozole loaded PEG-PLA nanoparticles: evaluation of apoptotic response of breast cancer cell lines
Yusra A Alyafee, Manal Alaamery, Shahad Bawazeer, Mansour S Almutairi, Badr Alghamdi, Nawaf Alomran, Atia Sheereen, Maha Daghestani & Salam Massadeh
Pages: 199-208
Published online: 28 Dec 2017
AbstractforPreparation of anastrozole loaded PEG-PLA nanoparticles: evaluation of apoptotic response of breast cancer cell lines | Full Text | References | PDF (2.6 MB)
  • 151 Views
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Open Access
Article
Antitumor effect of a new nano-vector with miRNA-135a on malignant glioma
Chaofeng Liang, Weitong Sun, Haiyong He, Baoyu Zhang, Cong Ling, Bocheng Wang, Tengchao Huang, Bo Hou & Ying Guo
Pages: 209-220
Published online: 29 Dec 2017
AbstractforAntitumor effect of a new nano-vector with miRNA-135a on malignant glioma | Full Text | References | PDF (2 MB)
  • 67 Views
  • 15 CrossRef citations
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Open Access
Article
Nano-graphene oxide composite for in vivo imaging
Sung-Chan Jang, Sung-Min Kang, Jun Young Lee, Seo Yeong Oh, AT Ezhil Vilian, Ilsong Lee, Young-Kyu Han, Jeong Hoon Park, Wan-Seob Cho, Changhyun Roh & Yun Suk Huh
Pages: 221-234
Published online: 03 Jan 2018
AbstractforNano-graphene oxide composite for in vivo imaging | Full Text | References | PDF (3 MB)
  • 111 Views
  • 27 CrossRef citations
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Open Access
Article
RETRACTED ARTICLE: Antimicrobial activity of silver nanoparticles encapsulated in poly-N-isopropylacrylamide-based polymeric nanoparticles
Muhammad Qasim, Nopphadol Udomluck, Jihyun Chang, Hansoo Park & Kyobum Kim
Pages: 235-249
Published online: 03 Jan 2018
AbstractforRETRACTED ARTICLE: Antimicrobial activity of silver nanoparticles encapsulated in poly-N-isopropylacrylamide-based polymeric nanoparticles | PDF (4.8 MB)
  • 65 Views
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Open Access
Article
Imaging and kinetics of the bimolecular complex formed by the tumor suppressor p53 with ubiquitin ligase COP1 as studied by atomic force microscopy and surface plasmon resonance
Ilaria Moscetti, Anna Rita Bizzarri & Salvatore Cannistraro
Pages: 251-259
Published online: 04 Jan 2018
AbstractforImaging and kinetics of the bimolecular complex formed by the tumor suppressor p53 with ubiquitin ligase COP1 as studied by atomic force microscopy and surface plasmon resonance | Full Text | References | PDF (2.1 MB)
  • 81 Views
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Open Access
Article
A novel sol-gel-derived calcium silicate cement with short setting time for application in endodontic repair of perforations
Bor-Shiunn Lee, Hong-Ping Lin, Jerry Chun-Chung Chan, Wei-Chuan Wang, Ping-Hsuan Hung, Yu-Hsin Tsai & Yuan-Ling Lee
Pages: 261-271
Published online: 08 Jan 2018
AbstractforA novel sol-gel-derived calcium silicate cement with short setting time for application in endodontic repair of perforations | Full Text | References | PDF (5 MB)
  • 147 Views
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Open Access
Article
Lactoferrin-modified rotigotine nanoparticles for enhanced nose-to-brain delivery: LESA-MS/MS-based drug biodistribution, pharmacodynamics, and neuroprotective effects
Xiuju Yan, Lixiao Xu, Chenchen Bi, Dongyu Duan, Liuxiang Chu, Xin Yu, Zimei Wu, Aiping Wang & Kaoxiang Sun
Pages: 273-281
Published online: 09 Jan 2018
AbstractforLactoferrin-modified rotigotine nanoparticles for enhanced nose-to-brain delivery: LESA-MS/MS-based drug biodistribution, pharmacodynamics, and neuroprotective effects | Full Text | References | PDF (6.3 MB)
  • 150 Views
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Open Access
Article
Effect of zirconium oxide nanoparticles addition on the optical and tensile properties of polymethyl methacrylate denture base material
Mohammed M Gad, Reem Abualsaud, Ahmed Rahoma, Ahmad M Al-Thobity, Khalid S Al-Abidi & Sultan Akhtar
Pages: 283-292
Published online: 09 Jan 2018
AbstractforEffect of zirconium oxide nanoparticles addition on the optical and tensile properties of polymethyl methacrylate denture base material | Full Text | References | PDF (1.1 MB)
  • 483 Views
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Open Access
Article
Targeting prostate cancer cells with hybrid elastin-like polypeptide/liposome nanoparticles
Wei Zhang, Yunmei Song, Preethi Eldi, Xiuli Guo, John D Hayball, Sanjay Garg & Hugo Albrecht
Pages: 293-305
Published online: 09 Jan 2018
AbstractforTargeting prostate cancer cells with hybrid elastin-like polypeptide/liposome nanoparticles | Full Text | References | PDF (1.7 MB)
  • 112 Views
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Open Access
Article
Nanosized soy phytosome-based thermogel as topical anti-obesity formulation: an approach for acceptable level of evidence of an effective novel herbal weight loss product
Shahira F El-Menshawe, Adel A Ali, Mohamed A Rabeh & Nermeen M Khalil
Pages: 307-318
Published online: 09 Jan 2018
AbstractforNanosized soy phytosome-based thermogel as topical anti-obesity formulation: an approach for acceptable level of evidence of an effective novel herbal weight loss product | Full Text | References | PDF (7.8 MB)
  • 397 Views
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Open Access

Review

Review Article
Overcoming tumor cell chemoresistance using nanoparticles: lysosomes are beneficial for (stearoyl) gemcitabine-incorporated solid lipid nanoparticles
Zhe Chen, Yuanqiang Zheng, Yanchun Shi & Zhengrong Cui
Pages: 319-336
Published online: 09 Jan 2018
AbstractforOvercoming tumor cell chemoresistance using nanoparticles: lysosomes are beneficial for (stearoyl) gemcitabine-incorporated solid lipid nanoparticles | Full Text | References | PDF (628.9 KB)
  • 153 Views
  • 26 CrossRef citations
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Open Access

Original Research

Article
Ultrasound-mediated cavitation does not decrease the activity of small molecule, antibody or viral-based medicines
Rachel Myers, Megan Grundy, Cliff Rowe, Christian M Coviello, Luca Bau, Philippe Erbs, Johann Foloppe, Jean-Marc Balloul, Colin Story, Constantin C Coussios & Robert Carlisle
Pages: 337-349
Published online: 10 Jan 2018
AbstractforUltrasound-mediated cavitation does not decrease the activity of small molecule, antibody or viral-based medicines | Full Text | References | PDF (4.4 MB)
  • 73 Views
  • 9 CrossRef citations
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Open Access
Article
Micelle-templated, poly(lactic-co-glycolic acid) nanoparticles for hydrophobic drug delivery
Gauri M Nabar, Kalpesh D Mahajan, Mark A Calhoun, Anthony D Duong, Matthew S Souva, Jihong Xu, Catherine Czeisler, Vinay K Puduvalli, José Javier Otero, Barbara E Wyslouzil & Jessica O Winter
Pages: 351-366
Published online: 28 Feb 2023
AbstractforMicelle-templated, poly(lactic-co-glycolic acid) nanoparticles for hydrophobic drug delivery | Full Text | References | PDF (6.9 MB)
  • 105 Views
  • 14 CrossRef citations
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Open Access
Article
Design and immunological evaluation of anti-CD205-tailored PLGA-based nanoparticulate cancer vaccine
Sheikh Tasnim Jahan, Sams MA Sadat & Azita Haddadi
Pages: 367-386
Published online: 11 Jan 2018
AbstractforDesign and immunological evaluation of anti-CD205-tailored PLGA-based nanoparticulate cancer vaccine | Full Text | References | PDF (3.5 MB)
  • 79 Views
  • 24 CrossRef citations
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Open Access
Article
In vivo therapeutic efficacy of TNFα silencing by folate-PEG-chitosan-DEAE/siRNA nanoparticles in arthritic mice
Qin Shi, Elsa-Patricia Rondon-Cavanzo, Isadora Pfeifer Dalla Picola, Marcio José Tiera, Xiaoling Zhang, Kerong Dai, Houda Abir Benabdoune, Mohamed Benderdour & Julio Cesar Fernandes
Pages: 387-402
Published online: 12 Jan 2018
AbstractforIn vivo therapeutic efficacy of TNFα silencing by folate-PEG-chitosan-DEAE/siRNA nanoparticles in arthritic mice | Full Text | References | PDF (13.7 MB)
  • 124 Views
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Open Access
Article
Dose reduction of bone morphogenetic protein-2 for bone regeneration using a delivery system based on lyophilization with trehalose
Xiaochen Zhang, Quan Yu, Yan-an Wang & Jun Zhao
Pages: 403-414
Published online: 12 Jan 2018
AbstractforDose reduction of bone morphogenetic protein-2 for bone regeneration using a delivery system based on lyophilization with trehalose | Full Text | References | PDF (3.5 MB)
  • 63 Views
  • 15 CrossRef citations
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Open Access
Article
Controlled drug delivery for glaucoma therapy using montmorillonite/Eudragit microspheres as an ion-exchange carrier
Shuangyan Tian, Juan Li, Qi Tao, Yawen Zhao, Zhufen Lv, Fan Yang, Haoyun Duan, Yanzhong Chen, Qingjun Zhou & Dongzhi Hou
Pages: 415-428
Published online: 12 Jan 2018
AbstractforControlled drug delivery for glaucoma therapy using montmorillonite/Eudragit microspheres as an ion-exchange carrier | Full Text | References | PDF (1.7 MB)
  • 84 Views
  • 17 CrossRef citations
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Open Access
Article
Magnetic immunoassay using CdSe/ZnS quantum dots as fluorescent probes to detect the level of DNA methyltransferase 1 in human serum sample
Fei Yu, Ya-min Xiong, Song-cheng Yu, Lei-liang He, Shan-shan Niu, Yu-ming Wu, Jie Liu, Ling-bo Qu, Li-e Liu & Yong-jun Wu
Pages: 429-437
Published online: 17 Jan 2018
AbstractforMagnetic immunoassay using CdSe/ZnS quantum dots as fluorescent probes to detect the level of DNA methyltransferase 1 in human serum sample | Full Text | References | PDF (876.1 KB)
  • 49 Views
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Open Access
Article
Development of biocompatible and VEGF-targeted paclitaxel nanodrugs on albumin and graphene oxide dual-carrier for photothermal-triggered drug delivery in vitro and in vivo
Wentao Deng, Juhui Qiu, Shaoting Wang, Zhi Yuan, Yuefeng Jia, Hailin Tan, Jiru Lu & Ruqiang Zheng
Pages: 439-453
Published online: 17 Jan 2018
AbstractforDevelopment of biocompatible and VEGF-targeted paclitaxel nanodrugs on albumin and graphene oxide dual-carrier for photothermal-triggered drug delivery in vitro and in vivo | Full Text | References | PDF (5.4 MB)
  • 109 Views
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Open Access
Article
Nanomedical studies of the restoration of nitric oxide/peroxynitrite balance in dysfunctional endothelium by 1,25-dihydroxy vitamin D3 – clinical implications for cardiovascular diseases
Alamzeb Khan, Hazem Dawoud & Tadeusz Malinski
Pages: 455-466
Published online: 19 Jan 2018
AbstractforNanomedical studies of the restoration of nitric oxide/peroxynitrite balance in dysfunctional endothelium by 1,25-dihydroxy vitamin D3 – clinical implications for cardiovascular diseases | Full Text | References | PDF (891.3 KB)
  • 76 Views
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Open Access
Article
Characterization of exosomes derived from Toxoplasma gondii and their functions in modulating immune responses
Yawen Li, Yuan Liu, Fangming Xiu, Jianing Wang, Hua Cong, Shenyi He, Yongyu Shi, Xiaoyan Wang, Xun Li & Huaiyu Zhou
Pages: 467-477
Published online: 19 Jan 2018
AbstractforCharacterization of exosomes derived from Toxoplasma gondii and their functions in modulating immune responses | Full Text | References | PDF (2.9 MB)
  • 239 Views
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Open Access
Article
Understanding the translocation mechanism of PLGA nanoparticles across round window membrane into the inner ear: a guideline for inner ear drug delivery based on nanomedicine
Liping Zhang, Yuan Xu, Wenjuan Cao, Shibao Xie, Lu Wen & Gang Chen
Pages: 479-492
Published online: 22 Jan 2018
AbstractforUnderstanding the translocation mechanism of PLGA nanoparticles across round window membrane into the inner ear: a guideline for inner ear drug delivery based on nanomedicine | Full Text | References | PDF (5.2 MB)
  • 112 Views
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Open Access
Article
Pharmacokinetics and in vitro/in vivo antitumor efficacy of aptamer-targeted Ecoflex® nanoparticles for docetaxel delivery in ovarian cancer
Erfaneh Ghassami, Jaleh Varshosaz, Ali Jahanian-Najafabadi, Mohsen Minaiyan, Parvin Rajabi & Effat Hayati
Pages: 493-504
Published online: 23 Jan 2018
AbstractforPharmacokinetics and in vitro/in vivo antitumor efficacy of aptamer-targeted Ecoflex® nanoparticles for docetaxel delivery in ovarian cancer | Full Text | References | PDF (1.4 MB)
  • 88 Views
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Open Access
Article
Nano-biphasic calcium phosphate/polyvinyl alcohol composites with enhanced bioactivity for bone repair via low-temperature three-dimensional printing and loading with platelet-rich fibrin
Yue Song, Kaifeng Lin, Shu He, Chunmei Wang, Shuaishuai Zhang, Donglin Li, Jimeng Wang, Tianqing Cao, Long Bi & Guoxian Pei
Pages: 505-523
Published online: 25 Jan 2018
AbstractforNano-biphasic calcium phosphate/polyvinyl alcohol composites with enhanced bioactivity for bone repair via low-temperature three-dimensional printing and loading with platelet-rich fibrin | Full Text | References | PDF (4.3 MB)
  • 150 Views
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Open Access
Article
One-step synthesis of gene carrier via gamma irradiation and its application in tumor gene therapy
Sung In Jeong, Seong-Cheol Park, Sun-Jeong Park, Eun-Ji Kim, Hun Heo, Jong-Seok Park, Hui-Jeong Gwon, Youn-Mook Lim & Mi-Kyeong Jang
Pages: 525-536
Published online: 25 Jan 2018
AbstractforOne-step synthesis of gene carrier via gamma irradiation and its application in tumor gene therapy | Full Text | References | PDF (3.4 MB)
  • 76 Views
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Open Access
Article
Copolymer micelles function as pH-responsive nanocarriers to enhance the cytotoxicity of a HER2 aptamer in HER2-positive breast cancer cells
Yinxing Shen, Junqi Zhang, Weiju Hao, Tong Wang, Jing Liu, Youhua Xie, Shouhong Xu & Honglai Liu
Pages: 537-553
Published online: 25 Jan 2018
AbstractforCopolymer micelles function as pH-responsive nanocarriers to enhance the cytotoxicity of a HER2 aptamer in HER2-positive breast cancer cells | Full Text | References | PDF (4.7 MB)
  • 127 Views
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Open Access
Article
Human β-defensin 3-combined gold nanoparticles for enhancement of osteogenic differentiation of human periodontal ligament cells in inflammatory microenvironments
Jing Zhou, Yangheng Zhang, Lingjun Li, Huangmei Fu, Wenrong Yang & Fuhua Yan
Pages: 555-567
Published online: 26 Jan 2018
AbstractforHuman β-defensin 3-combined gold nanoparticles for enhancement of osteogenic differentiation of human periodontal ligament cells in inflammatory microenvironments | Full Text | References | PDF (9.1 MB)
  • 69 Views
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Open Access
Article
Maturation of dendritic cells in vitro and immunological enhancement of mice in vivo by pachyman- and/or OVA-encapsulated poly(d,l-lactic acid) nanospheres
Sisi Zheng, Tao Qin, Yu Lu, Yifan Huang, Li Luo, Zhenguang Liu, Ruonan Bo, Yuanliang Hu, Jiaguo Liu & Deyun Wang
Pages: 569-583
Published online: 26 Jan 2018
AbstractforMaturation of dendritic cells in vitro and immunological enhancement of mice in vivo by pachyman- and/or OVA-encapsulated poly(d,l-lactic acid) nanospheres | Full Text | References | PDF (3.3 MB)
  • 49 Views
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Open Access
Article
Engineered exosome-mediated delivery of functionally active miR-26a and its enhanced suppression effect in HepG2 cells
Gaofeng Liang, Shu Kan, Yanliang Zhu, Shuying Feng, Wenpo Feng & Shegan Gao
Pages: 585-599
Published online: 30 Jan 2018
AbstractforEngineered exosome-mediated delivery of functionally active miR-26a and its enhanced suppression effect in HepG2 cells | Full Text | References | PDF (10.7 MB)
  • 322 Views
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Article
Sodium deoxycholate-decorated zein nanoparticles for a stable colloidal drug delivery system
Agnese Gagliardi, Donatella Paolino, Michelangelo Iannone, Ernesto Palma, Massimo Fresta & Donato Cosco
Pages: 601-614
Published online: 28 Feb 2023
AbstractforSodium deoxycholate-decorated zein nanoparticles for a stable colloidal drug delivery system | Full Text | References | PDF (5.4 MB)
  • 240 Views
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Open Access

Corrigendum

Correction
Cooperation of IRAK1/4 inhibitor and ABT-737 in nanoparticles for synergistic therapy of T cell acute lymphoblastic leukemia [Corrigendum]
Page: 615
Published online: 31 Jan 2018
CitationforCooperation of IRAK1/4 inhibitor and ABT-737 in nanoparticles for synergistic therapy of T cell acute lymphoblastic leukemia [Corrigendum] | Full Text | PDF (141.7 KB)
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Open Access

Original Research

Article
A novel therapeutic strategy for cartilage diseases based on lipid nanoparticle-RNAi delivery system
Shaowei Wang, Xiaochun Wei, Xiaojuan Sun, Chongwei Chen, Jingming Zhou, Ge Zhang, Heng Wu, Baosheng Guo & Lei Wei
Pages: 617-631
Published online: 31 Jan 2018
AbstractforA novel therapeutic strategy for cartilage diseases based on lipid nanoparticle-RNAi delivery system | Full Text | References | PDF (6 MB)
  • 136 Views
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Open Access
Article
Biofunctional Sr- and Si-loaded titania nanotube coating of Ti surfaces by anodization-hydrothermal process
Yong Huang, Xue Shen, Haixia Qiao, Hao Yang, Xuejiao Zhang, Yiyao Liu & Hejie Yang
Pages: 633-640
Published online: 31 Jan 2018
AbstractforBiofunctional Sr- and Si-loaded titania nanotube coating of Ti surfaces by anodization-hydrothermal process | Full Text | References | PDF (7.2 MB)
  • 51 Views
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Open Access
Article
pH-responsive charge-reversal polymer-functionalized boron nitride nanospheres for intracellular doxorubicin delivery
Shini Feng, Huijie Zhang, Chunyi Zhi, Xiao-Dong Gao & Hideki Nakanishi
Pages: 641-652
Published online: 31 Jan 2018
AbstractforpH-responsive charge-reversal polymer-functionalized boron nitride nanospheres for intracellular doxorubicin delivery | Full Text | References | PDF (2 MB)
  • 107 Views
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Open Access
Article
Bioreducible nanocapsules for folic acid-assisted targeting and effective tumor-specific chemotherapy
Qiangying Yi, Jin Ma, Ke Kang & Zhongwei Gu
Pages: 653-667
Published online: 31 Jan 2018
AbstractforBioreducible nanocapsules for folic acid-assisted targeting and effective tumor-specific chemotherapy | Full Text | References | PDF (7.4 MB)
  • 55 Views
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Open Access
Article
Nanoemulsion as a strategy for improving the oral bioavailability and anti-inflammatory activity of andrographolide
Ching-Chi Yen, Yi-Chen Chen, Ming-Tsang Wu, Chia-Chi Wang & Yu-Tse Wu
Pages: 669-680
Published online: 31 Jan 2018
AbstractforNanoemulsion as a strategy for improving the oral bioavailability and anti-inflammatory activity of andrographolide | Full Text | References | PDF (3.2 MB)
  • 284 Views
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Open Access
Article
Sustained-release of FGF-2 from a hybrid hydrogel of heparin-poloxamer and decellular matrix promotes the neuroprotective effects of proteins after spinal injury
He-Lin Xu, Fu-Rong Tian, Jian Xiao, Pian-Pian Chen, Jie Xu, Zi-Liang Fan, Jing-Jing Yang, Cui-Tao Lu & Ying-Zheng Zhao
Pages: 681-694
Published online: 01 Feb 2018
AbstractforSustained-release of FGF-2 from a hybrid hydrogel of heparin-poloxamer and decellular matrix promotes the neuroprotective effects of proteins after spinal injury | Full Text | References | PDF (2.1 MB)
  • 87 Views
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Open Access
Article
Biosynthesized silver and gold nanoparticles are potent antimycotics against opportunistic pathogenic yeasts and dermatophytes
Andrea Rónavári, Nóra Igaz, Mohana Krishna Gopisetty, Bettina Szerencsés, Dávid Kovács, Csaba Papp, Csaba Vágvölgyi, Imre Miklós Boros, Zoltán Kónya, Mónika Kiricsi & Ilona Pfeiffer
Pages: 695-703
Published online: 01 Feb 2018
AbstractforBiosynthesized silver and gold nanoparticles are potent antimycotics against opportunistic pathogenic yeasts and dermatophytes | Full Text | References | PDF (1.8 MB)
  • 228 Views
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Article
Intranasal delivery of Huperzine A to the brain using lactoferrin-conjugated N-trimethylated chitosan surface-modified PLGA nanoparticles for treatment of Alzheimer’s disease
Qingqing Meng, Aiping Wang, Hongchen Hua, Ying Jiang, Yiyun Wang, Hongjie Mu, Zimei Wu & Kaoxiang Sun
Pages: 705-718
Published online: 01 Feb 2018
AbstractforIntranasal delivery of Huperzine A to the brain using lactoferrin-conjugated N-trimethylated chitosan surface-modified PLGA nanoparticles for treatment of Alzheimer’s disease | Full Text | References | PDF (3.7 MB)
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Article
Fabrication of paclitaxel hybrid nanomicelles to treat resistant breast cancer via oral administration
Ling-Hui Dian, Ying-Jie Hu, Jia-Ye Lin, Jing-Ying Zhang, Yan Yan, Yi-Nuo Cui, Zhan-Bo Su & Wan-Liang Lu
Pages: 719-731
Published online: 02 Feb 2018
AbstractforFabrication of paclitaxel hybrid nanomicelles to treat resistant breast cancer via oral administration | Full Text | References | PDF (16.1 MB)
  • 76 Views
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Review

Review Article
Nanosilver: new ageless and versatile biomedical therapeutic scaffold
Shahid Ullah Khan, Tawfik A Saleh, Abdul Wahab, Muhammad Hafeez Ullah Khan, Dilfaraz Khan, Wasim Ullah Khan, Abdur Rahim, Sajid Kamal, Farman Ullah Khan & Shah Fahad
Pages: 733-762
Published online: 02 Feb 2018
AbstractforNanosilver: new ageless and versatile biomedical therapeutic scaffold | Full Text | References | PDF (1.9 MB)
  • 352 Views
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Original Research

Article
Aptamer–drug conjugate: targeted delivery of doxorubicin in a HER3 aptamer-functionalized liposomal delivery system reduces cardiotoxicity
Xiao-qian Dou, Hua Wang, Jing Zhang, Fang Wang, Gui-li Xu, Cheng-cheng Xu, Huan-hua Xu, Shen-si Xiang, Jie Fu & Hai-feng Song
Pages: 763-776
Published online: 05 Feb 2018
AbstractforAptamer–drug conjugate: targeted delivery of doxorubicin in a HER3 aptamer-functionalized liposomal delivery system reduces cardiotoxicity | Full Text | References | PDF (4.8 MB)
  • 228 Views
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Article
Gestational exposure to titanium dioxide nanoparticles impairs the placentation through dysregulation of vascularization, proliferation and apoptosis in mice
Lu Zhang, Xingxing Xie, Yigang Zhou, Dainan Yu, Yu Deng, Jiexiu Ouyang, Bei Yang, Dan Luo, Dalei Zhang & Haibin Kuang
Pages: 777-789
Published online: 28 Feb 2023
AbstractforGestational exposure to titanium dioxide nanoparticles impairs the placentation through dysregulation of vascularization, proliferation and apoptosis in mice | Full Text | References | PDF (9.6 MB)
  • 80 Views
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Article
Guided osteoporotic bone regeneration with composite scaffolds of mineralized ECM/heparin membrane loaded with BMP2-related peptide
Tingfang Sun, Man Liu, Sheng Yao, Yanhui Ji, Lei Shi, Kai Tang, Zekang Xiong, Fan Yang, Kaifang Chen & Xiaodong Guo
Pages: 791-804
Published online: 05 Feb 2018
AbstractforGuided osteoporotic bone regeneration with composite scaffolds of mineralized ECM/heparin membrane loaded with BMP2-related peptide | Full Text | References | PDF (12.4 MB)
  • 100 Views
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Article
Redox-responsive F127-folate/F127-disulfide bond-d-α-tocopheryl polyethylene glycol 1000 succinate/P123 mixed micelles loaded with paclitaxel for the reversal of multidrug resistance in tumors
Jing Lin, Chaoyue Zhao, Cuijuan Liu, Shiyao Fu, Luying Han, Xinping Lu & Chunrong Yang
Pages: 805-830
Published online: 07 Feb 2018
AbstractforRedox-responsive F127-folate/F127-disulfide bond-d-α-tocopheryl polyethylene glycol 1000 succinate/P123 mixed micelles loaded with paclitaxel for the reversal of multidrug resistance in tumors | Full Text | References | PDF (6.7 MB)
  • 77 Views
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Article
Increased skin permeation efficiency of imperatorin via charged ultradeformable lipid vesicles for transdermal delivery
Hongwei Lin, Qingchun Xie, Xin Huang, Junfeng Ban, Bo Wang, Xing Wei, Yanzhong Chen & Zhufen Lu
Pages: 831-842
Published online: 08 Feb 2018
AbstractforIncreased skin permeation efficiency of imperatorin via charged ultradeformable lipid vesicles for transdermal delivery | Full Text | References | PDF (1.8 MB)
  • 139 Views
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Article
A hydrogel biosensor for high selective and sensitive detection of amyloid-beta oligomers
Liping Sun, Yong Zhong, Jie Gui, Xianwu Wang, Xiaorong Zhuang & Jian Weng
Pages: 843-856
Published online: 08 Feb 2018
AbstractforA hydrogel biosensor for high selective and sensitive detection of amyloid-beta oligomers | Full Text | References | PDF (3.2 MB)
  • 221 Views
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Article
Nanoscale polysaccharide derivative as an AEG-1 siRNA carrier for effective osteosarcoma therapy
Fen Wang, Jia-Dong Pang, Lei-lei Huang, Ran Wang, Dan Li, Kang Sun, Lian-tang Wang & Li-Ming Zhang
Pages: 857-875
Published online: 08 Feb 2018
AbstractforNanoscale polysaccharide derivative as an AEG-1 siRNA carrier for effective osteosarcoma therapy | Full Text | References | PDF (3.8 MB)
  • 61 Views
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Article
Effects of silica–gentamicin nanohybrids on osteogenic differentiation of human osteoblast-like SaOS-2 cells
Wei He, Dina A Mosselhy, Yudong Zheng, Qingling Feng, Xiaoning Li, Xing Yang, Lina Yue & Simo-Pekka Hannula
Pages: 877-893
Published online: 09 Feb 2018
AbstractforEffects of silica–gentamicin nanohybrids on osteogenic differentiation of human osteoblast-like SaOS-2 cells | Full Text | References | PDF (14.1 MB)
  • 107 Views
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Article
Increased viability of fibroblasts when pretreated with ceria nanoparticles during serum deprivation
Francielli S Genier, Maximilian Bizanek, Thomas J Webster & Amit K Roy
Pages: 895-901
Published online: 28 Feb 2023
AbstractforIncreased viability of fibroblasts when pretreated with ceria nanoparticles during serum deprivation | Full Text | References | PDF (2.2 MB)
  • 51 Views
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Article
EGFR-targeted photodynamic therapy by curcumin-encapsulated chitosan/TPP nanoparticles
Wen-Hsuan Tsai, Kun-Hua Yu, Yi-Cheng Huang & Cheng-I Lee
Pages: 903-916
Published online: 09 Feb 2018
AbstractforEGFR-targeted photodynamic therapy by curcumin-encapsulated chitosan/TPP nanoparticles | Full Text | References | PDF (2.9 MB)
  • 199 Views
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Article
Functional intercalated nanocomposites with chitosan-glutathione-glycylsarcosine and layered double hydroxides for topical ocular drug delivery
Tingting Xu, Xiaoyue Xu, Yan Gu, Lei Fang & Feng Cao
Pages: 917-937
Published online: 13 Feb 2018
AbstractforFunctional intercalated nanocomposites with chitosan-glutathione-glycylsarcosine and layered double hydroxides for topical ocular drug delivery | Full Text | References | PDF (9.9 MB)
  • 143 Views
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Article
Redox-sensitive micelles composed of disulfide-linked Pluronic-linoleic acid for enhanced anticancer efficiency of brusatol
Jinming Zhang, Xiaobin Fang, Zeyong Li, Hon Fai Chan, Zhixiu Lin, Yitao Wang & Meiwan Chen
Pages: 939-956
Published online: 13 Feb 2018
AbstractforRedox-sensitive micelles composed of disulfide-linked Pluronic-linoleic acid for enhanced anticancer efficiency of brusatol | Full Text | References | PDF (6.1 MB)
  • 92 Views
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Article
Investigation of antitumor activities of trastuzumab delivered by PLGA nanoparticles
Barbara Colzani, Laura Pandolfi, Ada Hoti, Pietro Alessandro Iovene, Antonino Natalello, Svetlana Avvakumova, Miriam Colombo & Davide Prosperi
Pages: 957-973
Published online: 14 Feb 2018
AbstractforInvestigation of antitumor activities of trastuzumab delivered by PLGA nanoparticles | Full Text | References | PDF (6.7 MB)
  • 210 Views
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Article
Poly(lactic-co-glycolic acid)-loaded nanoparticles of betulinic acid for improved treatment of hepatic cancer: characterization, in vitro and in vivo evaluations
Pranesh Kumar, Ashok K Singh, Vinit Raj, Amit Rai, Amit K Keshari, Dinesh Kumar, Biswanath Maity, Anand Prakash, Sabyasachi Maiti & Sudipta Saha
Pages: 975-990
Published online: 16 Feb 2018
AbstractforPoly(lactic-co-glycolic acid)-loaded nanoparticles of betulinic acid for improved treatment of hepatic cancer: characterization, in vitro and in vivo evaluations | Full Text | References | PDF (1.9 MB)
  • 180 Views
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Article
Tannic acid-modified silver nanoparticles for wound healing: the importance of size
Piotr Orlowski, Magdalena Zmigrodzka, Emilia Tomaszewska, Katarzyna Ranoszek-Soliwoda, Monika Czupryn, Malgorzata Antos-Bielska, Janusz Szemraj, Grzegorz Celichowski, Jaroslaw Grobelny & Malgorzata Krzyzowska
Pages: 991-1007
Published online: 16 Feb 2018
AbstractforTannic acid-modified silver nanoparticles for wound healing: the importance of size | Full Text | References | PDF (4.4 MB)
  • 599 Views
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Article
Polymeric micelles for potentiated antiulcer and anticancer activities of naringin
Elham Abdelmonem Mohamed, Irhan Ibrahim Abu Hashim, Rehab Mohammad Yusif, Ahmed Abdel Aziz Shaaban, Ahmed Ramadan El-Sheakh, Mohammed Fawzy Hamed & Farid Abd Elreheem Badria
Pages: 1009-1027
Published online: 28 Feb 2023
AbstractforPolymeric micelles for potentiated antiulcer and anticancer activities of naringin | Full Text | References | PDF (7.3 MB)
  • 224 Views
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Article
Polyaspartic acid-anchored mesoporous silica nanoparticles for pH-responsive doxorubicin release
Abdul Hakeem, Fouzia Zahid, Guiting Zhan, Ping Yi, Hai Yang, Lu Gan & Xiangliang Yang
Pages: 1029-1040
Published online: 19 Feb 2018
AbstractforPolyaspartic acid-anchored mesoporous silica nanoparticles for pH-responsive doxorubicin release | Full Text | References | PDF (2.9 MB)
  • 133 Views
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Article
Origanum vulgare mediated green synthesis of biocompatible gold nanoparticles simultaneously possessing plasmonic, antioxidant and antimicrobial properties
Daniela Benedec, Ilioara Oniga, Flavia Cuibus, Bogdan Sevastre, Gabriela Stiufiuc, Mihaela Duma, Daniela Hanganu, Cristian Iacovita, Rares Stiufiuc & Constantin Mihai Lucaciu
Pages: 1041-1058
Published online: 20 Feb 2018
AbstractforOriganum vulgare mediated green synthesis of biocompatible gold nanoparticles simultaneously possessing plasmonic, antioxidant and antimicrobial properties | Full Text | References | PDF (4.9 MB)
  • 212 Views
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Article
Pivotal role of Acitretin nanovesicular gel for effective treatment of psoriasis: ex vivo–in vivo evaluation study
Irhan Ibrahim Abu Hashim, Noha Fawzy Abo El-Magd, Ahmed Ramadan El-Sheakh, Mohammed Fawzy Hamed & Abd El-Gawad Helmy Abd El-Gawad
Pages: 1059-1079
Published online: 20 Feb 2018
AbstractforPivotal role of Acitretin nanovesicular gel for effective treatment of psoriasis: ex vivo–in vivo evaluation study | Full Text | References | PDF (14.6 MB)
  • 433 Views
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Article
Adhesion, proliferation, and apoptosis in different molecular portraits of breast cancer treated with silver nanoparticles and its pathway-network analysis
Christian M Rodríguez-Razón, Irinea Yañez-Sánchez, Vicente O Ramos-Santillan, Celso Velásquez-Ordóñez, Susan A Gutiérrez-Rubio, Maritza R García-García, Roció I López-Roa, Pedro E Sánchez-Hernández, Adrian Daneri-Navarro & Trinidad García-Iglesias
Pages: 1081-1095
Published online: 22 Feb 2018
AbstractforAdhesion, proliferation, and apoptosis in different molecular portraits of breast cancer treated with silver nanoparticles and its pathway-network analysis | Full Text | References | PDF (2.6 MB)
  • 137 Views
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Article
Pharmacokinetics, distribution and anti-tumor efficacy of liposomal mitoxantrone modified with a luteinizing hormone-releasing hormone receptor-specific peptide
Linhua Zhang, Yanqing Ren, Yong Wang, Yingna He, Wei Feng & Cunxian Song
Pages: 1097-1105
Published online: 26 Feb 2018
AbstractforPharmacokinetics, distribution and anti-tumor efficacy of liposomal mitoxantrone modified with a luteinizing hormone-releasing hormone receptor-specific peptide | Full Text | References | PDF (2.4 MB)
  • 72 Views
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Article
Enhanced biocompatibility and osteogenic potential of mesoporous magnesium silicate/polycaprolactone/wheat protein composite scaffolds
Yun Gyeong Kang, Jie Wei, Ji Won Shin, Yan Ru Wu, Jiacan Su, Young Shik Park & Jung-Woog Shin
Pages: 1107-1117
Published online: 26 Feb 2018
AbstractforEnhanced biocompatibility and osteogenic potential of mesoporous magnesium silicate/polycaprolactone/wheat protein composite scaffolds | Full Text | References | PDF (7.3 MB)
  • 85 Views
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Article
Theranostic pH-sensitive nanoparticles for highly efficient targeted delivery of doxorubicin for breast tumor treatment
Changqie Pan, Yuqing Liu, Minyu Zhou, Wensheng Wang, Min Shi, Malcolm Xing & Wangjun Liao
Pages: 1119-1137
Published online: 28 Feb 2023
AbstractforTheranostic pH-sensitive nanoparticles for highly efficient targeted delivery of doxorubicin for breast tumor treatment | Full Text | References | PDF (6.9 MB)
  • 97 Views
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Article
Design and synthesis of nanoscaled IQCA-TAVV as a delivery system capable of antiplatelet activation, targeting arterial thrombus and releasing IQCA
Jianhui Wu, Haimei Zhu, Guodong Yang, Jianhong He, Yuji Wang, Shurui Zhao, Xiaoyi Zhang, Lin Gui, Ming Zhao & Shiqi Peng
Pages: 1139-1158
Published online: 26 Feb 2018
AbstractforDesign and synthesis of nanoscaled IQCA-TAVV as a delivery system capable of antiplatelet activation, targeting arterial thrombus and releasing IQCA | Full Text | References | PDF (9.9 MB)
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Article
Combined use of vancomycin-modified Ag-coated magnetic nanoparticles and secondary enhanced nanoparticles for rapid surface-enhanced Raman scattering detection of bacteria
Chongwen Wang, Bing Gu, Qiqi Liu, Yuanfeng Pang, Rui Xiao & Shengqi Wang
Pages: 1159-1178
Published online: 28 Feb 2023
AbstractforCombined use of vancomycin-modified Ag-coated magnetic nanoparticles and secondary enhanced nanoparticles for rapid surface-enhanced Raman scattering detection of bacteria | Full Text | References | PDF (4 MB)
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Review

Review Article
Nanotechnology-based drug delivery systems for control of microbial biofilms: a review
Matheus Aparecido Dos Santos Ramos, Patrícia Bento Da Silva, Larissa Spósito, Luciani Gaspar De Toledo, Bruna Vidal Bonifácio, Camila Fernanda Rodero, Karen Cristina Dos Santos, Marlus Chorilli & Taís Maria Bauab
Pages: 1179-1213
Published online: 27 Feb 2018
AbstractforNanotechnology-based drug delivery systems for control of microbial biofilms: a review | Full Text | References | PDF (2 MB)
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Original Research

Article
Noninvasive visualization of early osteoarthritic cartilage using targeted nanosomes in a destabilization of the medial meniscus mouse model
Hongsik Cho, Byoung Ju Kim, Sang-Hyug Park, Karen A Hasty & Byoung-Hyun Min
Pages: 1215-1224
Published online: 28 Feb 2023
AbstractforNoninvasive visualization of early osteoarthritic cartilage using targeted nanosomes in a destabilization of the medial meniscus mouse model | Full Text | References | PDF (1.8 MB)
  • 115 Views
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Article
Colon-targeted delivery of cyclosporine A using dual-functional Eudragit® FS30D/PLGA nanoparticles ameliorates murine experimental colitis
Muhammad Naeem, Junhwan Bae, Murtada A Oshi, Min-Soo Kim, Hyung Ryong Moon, Bok Luel Lee, Eunok Im, Yunjin Jung & Jin-Wook Yoo
Pages: 1225-1240
Published online: 28 Feb 2018
AbstractforColon-targeted delivery of cyclosporine A using dual-functional Eudragit® FS30D/PLGA nanoparticles ameliorates murine experimental colitis | Full Text | References | PDF (16.8 MB)
  • 335 Views
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Article
Targeted delivery of anti-miR-155 by functionalized mesoporous silica nanoparticles for colorectal cancer therapy
Yang Li, Yanhong Duo, Jiangang Bi, Xiaowei Zeng, Lin Mei, Shiyun Bao, Lisheng He, Aijun Shan, Yue Zhang & Xiaofang Yu
Pages: 1241-1256
Published online: 01 Mar 2018
AbstractforTargeted delivery of anti-miR-155 by functionalized mesoporous silica nanoparticles for colorectal cancer therapy | Full Text | References | PDF (3 MB)
  • 189 Views
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Article
The evaluation of zinc and copper content in tooth enamel without any pathological changes – an in vitro study
Elzbieta Klimuszko, Karolina Orywal, Teresa Sierpinska, Jarosław Sidun & Maria Golebiewska
Pages: 1257-1264
Published online: 02 Mar 2018
AbstractforThe evaluation of zinc and copper content in tooth enamel without any pathological changes – an in vitro study | Full Text | References | PDF (694.5 KB)
  • 77 Views
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Article
Targeted co-delivery of Beclin 1 siRNA and FTY720 to hepatocellular carcinoma by calcium phosphate nanoparticles for enhanced anticancer efficacy
Jun-Yi Wu, Zhong-Xia Wang, Guang Zhang, Xian Lu, Guang-Hui Qiang, Wei Hu, An-Lai Ji, Jun-Hua Wu & Chun-Ping Jiang
Pages: 1265-1280
Published online: 05 Mar 2018
AbstractforTargeted co-delivery of Beclin 1 siRNA and FTY720 to hepatocellular carcinoma by calcium phosphate nanoparticles for enhanced anticancer efficacy | Full Text | References | PDF (3 MB)
  • 75 Views
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Article
A facile doxorubicin-dichloroacetate conjugate nanomedicine with high drug loading for safe drug delivery
Conglian Yang, Tingting Wu, Yuting Qin, Yan Qi, Yu Sun, Miao Kong, Xue Jiang, Xianya Qin, Yaqi Shen & Zhiping Zhang
Pages: 1281-1293
Published online: 06 Mar 2018
AbstractforA facile doxorubicin-dichloroacetate conjugate nanomedicine with high drug loading for safe drug delivery | Full Text | References | PDF (5.5 MB)
  • 98 Views
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Corrigendum

Correction
Ex vivo distribution of gold nanoparticles in choroidal melanoma [Corrigendum]
Page: 1295
Published online: 06 Mar 2018
CitationforEx vivo distribution of gold nanoparticles in choroidal melanoma [Corrigendum] | Full Text | PDF (140.5 KB)
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Original Research

Article
Inhibition of cell proliferation and migration through nucleobase-modified polyamidoamine-mediated p53 delivery
Haobo Han, Wenqi Chen, Jiebing Yang, Xiao Liang, Yudi Wang, Quanshun Li, Yan Yang & Kun Li
Pages: 1297-1311
Published online: 06 Mar 2018
AbstractforInhibition of cell proliferation and migration through nucleobase-modified polyamidoamine-mediated p53 delivery | Full Text | References | PDF (6 MB)
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Article
Pomegranate extract-loaded solid lipid nanoparticles: design, optimization, and in vitro cytotoxicity study
Noha M Badawi, Mahmoud H Teaima, Khalid M El-Say, Dalia A Attia, Mohamed A El-Nabarawi & Mohey M Elmazar
Pages: 1313-1326
Published online: 06 Mar 2018
AbstractforPomegranate extract-loaded solid lipid nanoparticles: design, optimization, and in vitro cytotoxicity study | Full Text | References | PDF (2.5 MB)
  • 230 Views
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Article
Development of liposomal pemetrexed for enhanced therapy against multidrug resistance mediated by ABCC5 in breast cancer
Fang Bai, You Yin, Ting Chen, Jihui Chen, Meixin Ge, Yunshu Lu, Fangyuan Xie, Jian Zhang, Kejin Wu & Yan Liu
Pages: 1327-1339
Published online: 06 Mar 2018
AbstractforDevelopment of liposomal pemetrexed for enhanced therapy against multidrug resistance mediated by ABCC5 in breast cancer | Full Text | References | PDF (2.9 MB)
  • 109 Views
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Article
Anti-Toxoplasma activity of various molecular weights and concentrations of chitosan nanoparticles on tachyzoites of RH strain
Aref Teimouri, Sanaz Jafarpour Azami, Hossein Keshavarz, Fariba Esmaeili, Rasoul Alimi, Sara Ayazian Mavi & Saeedeh Shojaee
Pages: 1341-1351
Published online: 08 Mar 2018
AbstractforAnti-Toxoplasma activity of various molecular weights and concentrations of chitosan nanoparticles on tachyzoites of RH strain | Full Text | References | PDF (1.5 MB)
  • 160 Views
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Article
Acoustically enhanced microfluidic mixer to synthesize highly uniform nanodrugs without the addition of stabilizers
Nguyen Hoai An Le, Hoang Van Phan, Jiaqi Yu, Hak-Kim Chan, Adrian Neild & Tuncay Alan
Pages: 1353-1359
Published online: 08 Mar 2018
AbstractforAcoustically enhanced microfluidic mixer to synthesize highly uniform nanodrugs without the addition of stabilizers | Full Text | References | PDF (950 KB)
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Article
DNA nanoparticles are safe and nontoxic in non-human primate eyes
Ryan A Kelley, Shannon M Conley, Rasha Makkia, Jamie N Watson, Zongchao Han, Mark J Cooper & Muna I Naash
Pages: 1361-1379
Published online: 08 Mar 2018
AbstractforDNA nanoparticles are safe and nontoxic in non-human primate eyes | Full Text | References | PDF (5 MB)
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Article
Design of pH-sensitive methotrexate prodrug-targeted curcumin nanoparticles for efficient dual-drug delivery and combination cancer therapy
Jiajiang Xie, Zhongxiong Fan, Yang Li, Yinying Zhang, Fei Yu, Guanghao Su, Liya Xie & Zhenqing Hou
Pages: 1381-1398
Published online: 09 Mar 2018
AbstractforDesign of pH-sensitive methotrexate prodrug-targeted curcumin nanoparticles for efficient dual-drug delivery and combination cancer therapy | Full Text | References | PDF (14.4 MB)
  • 207 Views
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Article
The impact of liposomal linolenic acid on gastrointestinal microbiota in mice
Xuan-xuan Li, Si Shi, Lan Rong, Mei-qing Feng & Liang Zhong
Pages: 1399-1409
Published online: 09 Mar 2018
AbstractforThe impact of liposomal linolenic acid on gastrointestinal microbiota in mice | Full Text | References | PDF (9.2 MB)
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Article
Biosynthesis of Au, Ag and Au–Ag bimetallic nanoparticles using protein extracts of Deinococcus radiodurans and evaluation of their cytotoxicity
Jiulong Li, Bing Tian, Tao Li, Shang Dai, Yulan Weng, Jianjiang Lu, Xiaolin Xu, Ye Jin, Renjiang Pang & Yuejin Hua
Pages: 1411-1424
Published online: 09 Mar 2018
AbstractforBiosynthesis of Au, Ag and Au–Ag bimetallic nanoparticles using protein extracts of Deinococcus radiodurans and evaluation of their cytotoxicity | Full Text | References | PDF (13.1 MB)
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Review

Review Article
Tumor-targeting delivery of herb-based drugs with cell-penetrating/tumor-targeting peptide-modified nanocarriers
Dereje Kebebe, Yuanyuan Liu, Yumei Wu, Maikhone Vilakhamxay, Zhidong Liu & Jiawei Li
Pages: 1425-1442
Published online: 09 Mar 2018
AbstractforTumor-targeting delivery of herb-based drugs with cell-penetrating/tumor-targeting peptide-modified nanocarriers | Full Text | References | PDF (915.2 KB)
  • 216 Views
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Original Research

Article
Co-delivery of Aurora-A inhibitor XY-4 and Bcl-xl siRNA enhances antitumor efficacy for melanoma therapy
Xingmei Duan, Minjie Mu, Junfeng Yan, Lan Bai, Lei Zhong, Yuxuan Zhu, Haixia Pan, Mei Zhang & Jianyou Shi
Pages: 1443-1456
Published online: 09 Mar 2018
AbstractforCo-delivery of Aurora-A inhibitor XY-4 and Bcl-xl siRNA enhances antitumor efficacy for melanoma therapy | Full Text | References | PDF (8.5 MB)
  • 78 Views
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Article
Endocytic mechanisms and osteoinductive profile of hydroxyapatite nanoparticles in human umbilical cord Wharton’s jelly-derived mesenchymal stem cells
Xingxing Shi, Kai Zhou, Fei Huang, Juan Zhang & Chen Wang
Pages: 1457-1470
Published online: 12 Mar 2018
AbstractforEndocytic mechanisms and osteoinductive profile of hydroxyapatite nanoparticles in human umbilical cord Wharton’s jelly-derived mesenchymal stem cells | Full Text | References | PDF (18.6 MB)
  • 87 Views
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Article
Targeting experimental orthotopic glioblastoma with chitosan-based superparamagnetic iron oxide nanoparticles (CS-DX-SPIONs)
Maxim Shevtsov, Boris Nikolaev, Yaroslav Marchenko, Ludmila Yakovleva, Nikita Skvortsov, Anton Mazur, Peter Tolstoy, Vyacheslav Ryzhov & Gabriele Multhoff
Pages: 1471-1482
Published online: 12 Mar 2018
AbstractforTargeting experimental orthotopic glioblastoma with chitosan-based superparamagnetic iron oxide nanoparticles (CS-DX-SPIONs) | Full Text | References | PDF (2.8 MB)
  • 155 Views
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Article
Biodistribution, pharmacokinetics, and toxicity of dendrimer-coated iron oxide nanoparticles in BALB/c mice
Marzieh Salimi, Saeed Sarkar, Samaneh Fathi, Ali Mohammad Alizadeh, Reza Saber, Fatemeh Moradi & Hamid Delavari
Pages: 1483-1493
Published online: 13 Mar 2018
AbstractforBiodistribution, pharmacokinetics, and toxicity of dendrimer-coated iron oxide nanoparticles in BALB/c mice | Full Text | References | PDF (2 MB)
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Article
The theranostic efficiency of tumor-specific, pH-responsive, peptide-modified, liposome-containing paclitaxel and superparamagnetic iron oxide nanoparticles
Xiu-Chai Zheng, Wei Ren, Shuang Zhang, Ting Zhong, Xiao-Chuan Duan, Yi-Fan Yin, Mei-Qi Xu, Yan-Li Hao, Zhan-Tao Li, Hui Li, Man Liu, Zhuo-Yue Li & Xuan Zhang
Pages: 1495-1504
Published online: 13 Mar 2018
AbstractforThe theranostic efficiency of tumor-specific, pH-responsive, peptide-modified, liposome-containing paclitaxel and superparamagnetic iron oxide nanoparticles | Full Text | References | PDF (3.2 MB)
  • 147 Views
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Article
Antitumor effect of a Pt-loaded nanocomposite based on graphene quantum dots combats hypoxia-induced chemoresistance of oral squamous cell carcinoma
Zheng Wei, Xiteng Yin, Yu Cai, Wenguang Xu, Chuanhui Song, Yufeng Wang, Jingwei Zhang, An Kang, Zhiyong Wang & Wei Han
Pages: 1505-1524
Published online: 13 Mar 2018
AbstractforAntitumor effect of a Pt-loaded nanocomposite based on graphene quantum dots combats hypoxia-induced chemoresistance of oral squamous cell carcinoma | Full Text | References | PDF (3.2 MB)
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Article
Influence of luminescent graphene quantum dots on trypsin activity
Tanveer A Tabish, Md Zahidul I Pranjol, Ilayda Karadag, David W Horsell, Jacqueline L Whatmore & Shaowei Zhang
Pages: 1525-1538
Published online: 15 Mar 2018
AbstractforInfluence of luminescent graphene quantum dots on trypsin activity | Full Text | References | PDF (2.2 MB)
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Article
siRNA-loaded selenium nanoparticle modified with hyaluronic acid for enhanced hepatocellular carcinoma therapy
Yu Xia, Min Guo, Tiantian Xu, Yinghua Li, Changbing Wang, Zhengfang Lin, Mingqi Zhao & Bing Zhu
Pages: 1539-1552
Published online: 15 Mar 2018
AbstractforsiRNA-loaded selenium nanoparticle modified with hyaluronic acid for enhanced hepatocellular carcinoma therapy | Full Text | References | PDF (5.9 MB)
  • 200 Views
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Article
A novel electrospun-aligned nanoyarn/three-dimensional porous nanofibrous hybrid scaffold for annulus fibrosus tissue engineering
Jun Ma, Yunfei He, Xilin Liu, Weiming Chen, An Wang, Chia-Ying Lin, Xiumei Mo & Xiaojian Ye
Pages: 1553-1567
Published online: 15 Mar 2018
AbstractforA novel electrospun-aligned nanoyarn/three-dimensional porous nanofibrous hybrid scaffold for annulus fibrosus tissue engineering | Full Text | References | PDF (14.9 MB)
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Review

Review Article
Recent developments in solid lipid nanoparticle and surface-modified solid lipid nanoparticle delivery systems for oral delivery of phyto-bioactive compounds in various chronic diseases
Palanivel Ganesan, Prakash Ramalingam, Govindarajan Karthivashan, Young Tag Ko & Dong-Kug Choi
Pages: 1569-1583
Published online: 15 Mar 2018
AbstractforRecent developments in solid lipid nanoparticle and surface-modified solid lipid nanoparticle delivery systems for oral delivery of phyto-bioactive compounds in various chronic diseases | Full Text | References | PDF (2.1 MB)
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Original Research

Article
Paclitaxel-loaded redox-sensitive nanoparticles based on hyaluronic acid-vitamin E succinate conjugates for improved lung cancer treatment
Yu Song, Han Cai, Tingjie Yin, Meirong Huo, Ping Ma, Jianping Zhou & Wenfang Lai
Pages: 1585-1600
Published online: 15 Mar 2018
AbstractforPaclitaxel-loaded redox-sensitive nanoparticles based on hyaluronic acid-vitamin E succinate conjugates for improved lung cancer treatment | Full Text | References | PDF (7.2 MB)
  • 226 Views
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Article
Targeted therapy of intracranial glioma model mice with curcumin nanoliposomes
Ming Zhao, Mengnan Zhao, Chen Fu, Yang Yu & Ailing Fu
Pages: 1601-1610
Published online: 15 Mar 2018
AbstractforTargeted therapy of intracranial glioma model mice with curcumin nanoliposomes | Full Text | References | PDF (2.2 MB)
  • 127 Views
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Article
Tri-block polymer with interfacial layer formation ability and its use in maintaining supersaturated drug solution after dissolution of solid dispersions
Ji-Jun Fu & Cheng-Cheng Liu
Pages: 1611-1619
Published online: 16 Mar 2018
AbstractforTri-block polymer with interfacial layer formation ability and its use in maintaining supersaturated drug solution after dissolution of solid dispersions | Full Text | References | PDF (1.5 MB)
  • 69 Views
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Article
Hepatocellular carcinoma-targeted effect of configurations and groups of glycyrrhetinic acid by evaluation of its derivative-modified liposomes
Yuqi Sun, Chunmei Dai, Meilin Yin, Jinghua Lu, Haiyang Hu & Dawei Chen
Pages: 1621-1632
Published online: 16 Mar 2018
AbstractforHepatocellular carcinoma-targeted effect of configurations and groups of glycyrrhetinic acid by evaluation of its derivative-modified liposomes | Full Text | References | PDF (2.8 MB)
  • 105 Views
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Article
Polymer nanofiber-based microchips for EGFR mutation analysis of circulating tumor cells in lung adenocarcinoma
Wenting Jiang, Han Wang, Yongmei Cui, Yiyan Lei, Yuefeng Wang, Di Xu, Neng Jiang, Yangshan Chen, Yu Sun, Yang Zhang, Jessica Cao & Zunfu Ke
Pages: 1633-1642
Published online: 28 Feb 2023
AbstractforPolymer nanofiber-based microchips for EGFR mutation analysis of circulating tumor cells in lung adenocarcinoma | Full Text | References | PDF (2 MB)
  • 61 Views
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Article
Immobilization of a carbon nanomaterial-based localized drug-release system using a bispecific material-binding peptide
Katsutoshi Kokubun, Sachiko Matsumura, Masako Yudasaka, Sumio Iijima & Kiyotaka Shiba
Pages: 1643-1652
Published online: 16 Mar 2018
AbstractforImmobilization of a carbon nanomaterial-based localized drug-release system using a bispecific material-binding peptide | Full Text | References | PDF (2.2 MB)
  • 66 Views
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Article
Imaging of extracellular vesicles derived from human bone marrow mesenchymal stem cells using fluorescent and magnetic labels
Sylwia Dabrowska, Andrea Del Fattore, Elzbieta Karnas, Malgorzata Frontczak-Baniewicz, Hanna Kozlowska, Maurizio Muraca, Miroslaw Janowski & Barbara Lukomska
Pages: 1653-1664
Published online: 19 Mar 2018
AbstractforImaging of extracellular vesicles derived from human bone marrow mesenchymal stem cells using fluorescent and magnetic labels | Full Text | References | PDF (4.4 MB)
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Article
Kaempferol-immobilized titanium dioxide promotes formation of new bone: effects of loading methods on bone marrow stromal cell differentiation in vivo and in vitro
Shuhei Tsuchiya, Keisuke Sugimoto, Hisanobu Kamio, Kazuto Okabe, Kensuke Kuroda, Masazumi Okido & Hideharu Hibi
Pages: 1665-1676
Published online: 19 Mar 2018
AbstractforKaempferol-immobilized titanium dioxide promotes formation of new bone: effects of loading methods on bone marrow stromal cell differentiation in vivo and in vitro | Full Text | References | PDF (3.4 MB)
  • 65 Views
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Article
Dexibuprofen nanocrystals with improved therapeutic performance: fabrication, characterization, in silico modeling, and in vivo evaluation
Naseem Ullah, Shahzeb Khan, Shaimaa Ahmed, Thirumala Govender, Hani S Faidah, Marcel de Matas, Muhammad Shahid, Muhammad Usman Minhas, Muhammad Sohail & Muhammad Khurram
Pages: 1677-1692
Published online: 20 Mar 2018
AbstractforDexibuprofen nanocrystals with improved therapeutic performance: fabrication, characterization, in silico modeling, and in vivo evaluation | Full Text | References | PDF (3.1 MB)
  • 188 Views
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Article
Interaction of poly-l-lysine coating and heparan sulfate proteoglycan on magnetic nanoparticle uptake by tumor cells
Wei Xiong Siow, Yi-Ting Chang, Michal Babič, Yi-Ching Lu, Daniel Horák & Yunn-Hwa Ma
Pages: 1693-1706
Published online: 20 Mar 2018
AbstractforInteraction of poly-l-lysine coating and heparan sulfate proteoglycan on magnetic nanoparticle uptake by tumor cells | Full Text | References | PDF (4.9 MB)
  • 121 Views
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Article
Biomimetic mineralized strontium-doped hydroxyapatite on porous poly(l-lactic acid) scaffolds for bone defect repair
Min Ge, Kun Ge, Fei Gao, Weixiao Yan, Huifang Liu, Li Xue, Yi Jin, Haiyun Ma & Jinchao Zhang
Pages: 1707-1721
Published online: 20 Mar 2018
AbstractforBiomimetic mineralized strontium-doped hydroxyapatite on porous poly(l-lactic acid) scaffolds for bone defect repair | Full Text | References | PDF (11.3 MB)
  • 141 Views
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Article
Surfactin-based nanoparticles loaded with doxorubicin to overcome multidrug resistance in cancers
Wenjing Huang, Yan Lang, Abdul Hakeem, Yan Lei, Lu Gan & Xiangliang Yang
Pages: 1723-1736
Published online: 28 Feb 2023
AbstractforSurfactin-based nanoparticles loaded with doxorubicin to overcome multidrug resistance in cancers | Full Text | References | PDF (3.1 MB)
  • 95 Views
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Article
NaCl: for the safer in vivo use of antibacterial silver based nanoparticles
Mingzhuo Liu, Huiqing Zhang, Xiangwei Song, Chaochao Wei, Zhenfang Xiong, Fen Yu, Chen Li, Fanrong Ai, Guanghua Guo & Xiaolei Wang
Pages: 1737-1748
Published online: 21 Mar 2018
AbstractforNaCl: for the safer in vivo use of antibacterial silver based nanoparticles | Full Text | References | PDF (4.6 MB)
  • 72 Views
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Article
A promising magnetic resonance stem cell tracer based on natural biomaterials in a biological system: manganese(II) chelated to melanin nanoparticles
Shi-Jie Liu, Ling-Jie Wang, Ying Qiao, Hua Zhang, Li-Ping Li, Jing-Hua Sun, Sheng He, Wen Xu, Xi Yang, Wen-Wen Cai, Jian-Ding Li, Bin-Quan Wang & Rui-Ping Zhang
Pages: 1749-1759
Published online: 21 Mar 2018
AbstractforA promising magnetic resonance stem cell tracer based on natural biomaterials in a biological system: manganese(II) chelated to melanin nanoparticles | Full Text | References | PDF (2.6 MB)
  • 56 Views
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Article
Propylthiouracil-coated biodegradable polymer inhibited neointimal formation and enhanced re-endothelialization after vascular injury
Shang-Hung Chang, Cheng-Hung Lee, Yung-Hsin Yeh, Shih-Jung Liu, Chao-Jan Wang, Ming-Yi Hsu & Wei-Jan Chen
Pages: 1761-1771
Published online: 21 Mar 2018
AbstractforPropylthiouracil-coated biodegradable polymer inhibited neointimal formation and enhanced re-endothelialization after vascular injury | Full Text | References | PDF (3.3 MB)
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Article
Construction and application of a liver cancer-targeting drug delivery system based on core–shell gold nanocages
Mengfei Ji, Xiaojing Qiu, Lin Hou, Shengnan Huang, Yuanmin Li, Yang Liu, Shaofeng Duan & Yurong Hu
Pages: 1773-1789
Published online: 21 Mar 2018
AbstractforConstruction and application of a liver cancer-targeting drug delivery system based on core–shell gold nanocages | Full Text | References | PDF (16.9 MB)
  • 143 Views
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Article
Ultrasound molecular imaging of breast cancer in MCF-7 orthotopic mice using gold nanoshelled poly(lactic-co-glycolic acid) nanocapsules: a novel dual-targeted ultrasound contrast agent
Li Xu, Jing Du, Caifeng Wan, Yu Zhang, Shaowei Xie, Hongli Li, Hong Yang & Fenghua Li
Pages: 1791-1807
Published online: 21 Mar 2018
AbstractforUltrasound molecular imaging of breast cancer in MCF-7 orthotopic mice using gold nanoshelled poly(lactic-co-glycolic acid) nanocapsules: a novel dual-targeted ultrasound contrast agent | Full Text | References | PDF (4.3 MB)
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Article
Porous Se@SiO2 nanocomposites protect the femoral head from methylprednisolone-induced osteonecrosis
Guoying Deng, Chenyun Dai, Jinyuan Chen, Anqi Ji, Jingpeng Zhao, Yue Zhai, Yingjie Kang, Xijian Liu, Yin Wang & Qiugen Wang
Pages: 1809-1818
Published online: 22 Mar 2018
AbstractforPorous Se@SiO2 nanocomposites protect the femoral head from methylprednisolone-induced osteonecrosis | Full Text | References | PDF (5.8 MB)
  • 153 Views
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Article
Noninvasive evaluation of the migration effect of transplanted endothelial progenitor cells in ischemic muscle using a multimodal imaging agent
Xingui Peng, Cong Li, Yingying Bai, Xinyi Wang, Yi Zhang, Yanli An, Gao-Jun Teng & Shenghong Ju
Pages: 1819-1829
Published online: 28 Feb 2023
AbstractforNoninvasive evaluation of the migration effect of transplanted endothelial progenitor cells in ischemic muscle using a multimodal imaging agent | Full Text | References | PDF (4.3 MB)
  • 53 Views
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Article
Trastuzumab- and Fab′ fragment-modified curcumin PEG-PLGA nanoparticles: preparation and evaluation in vitro and in vivo
Dongyu Duan, Aiping Wang, Ling Ni, Liping Zhang, Xiuju Yan, Ying Jiang, Hongjie Mu, Zimei Wu, Kaoxiang Sun & Youxin Li
Pages: 1831-1840
Published online: 22 Mar 2018
AbstractforTrastuzumab- and Fab′ fragment-modified curcumin PEG-PLGA nanoparticles: preparation and evaluation in vitro and in vivo | Full Text | References | PDF (2.3 MB)
  • 133 Views
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Article
Synovitis in mice with inflammatory arthritis monitored with quantitative analysis of dynamic contrast-enhanced NIR fluorescence imaging using iRGD-targeted liposomes as fluorescence probes
Hao Wu, Haohan Wu, Yanni He, Zhen Gan, Zhili Xu, Meijun Zhou, Sai Liu & Hongmei Liu
Pages: 1841-1850
Published online: 23 Mar 2018
AbstractforSynovitis in mice with inflammatory arthritis monitored with quantitative analysis of dynamic contrast-enhanced NIR fluorescence imaging using iRGD-targeted liposomes as fluorescence probes | Full Text | References | PDF (8.6 MB)
  • 57 Views
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Article
Superparamagnetic iron oxide nanoparticles modified with polyethylenimine and galactose for siRNA targeted delivery in hepatocellular carcinoma therapy
Zhen Yang, Juanli Duan, Jianlin Wang, Qi Liu, Runze Shang, Xisheng Yang, Peng Lu, Congcong Xia, Lin Wang & Kefeng Dou
Pages: 1851-1865
Published online: 26 Mar 2018
AbstractforSuperparamagnetic iron oxide nanoparticles modified with polyethylenimine and galactose for siRNA targeted delivery in hepatocellular carcinoma therapy | Full Text | References | PDF (2.6 MB)
  • 119 Views
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Corrigendum

Correction
Development of transmucosal patch loaded with anesthetic and analgesic for dental procedures and in vivo evaluation [Corrigendum]
Page: 1867
Published online: 27 Mar 2018
CitationforDevelopment of transmucosal patch loaded with anesthetic and analgesic for dental procedures and in vivo evaluation [Corrigendum] | Full Text | PDF (144.9 KB)
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Original Research

Article
Enhanced permeability of blood–brain barrier and targeting function of brain via borneol-modified chemically solid lipid nanoparticle
Hui Song, Man Wei, Nan Zhang, He Li, Xiaochuan Tan, Yujia Zhang & Wensheng Zheng
Pages: 1869-1879
Published online: 28 Mar 2018
AbstractforEnhanced permeability of blood–brain barrier and targeting function of brain via borneol-modified chemically solid lipid nanoparticle | Full Text | References | PDF (3.9 MB)
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Article
Microstructures, mechanical, and biological properties of a novel Ti-6V-4V/zinc surface nanocomposite prepared by friction stir processing
Chenyuan Zhu, Yuting Lv, Chao Qian, Zihao Ding, Ting Jiao, Xiaoyu Gu, Eryi Lu, Liqiang Wang & Fuqiang Zhang
Pages: 1881-1898
Published online: 28 Mar 2018
AbstractforMicrostructures, mechanical, and biological properties of a novel Ti-6V-4V/zinc surface nanocomposite prepared by friction stir processing | Full Text | References | PDF (7.6 MB)
  • 142 Views
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Article
Dextran-coated superparamagnetic iron oxide nanoparticles for magnetic resonance imaging: evaluation of size-dependent imaging properties, storage stability and safety
Harald Unterweger, László Dézsi, Jasmin Matuszak, Christina Janko, Marina Poettler, Jutta Jordan, Tobias Bäuerle, János Szebeni, Tobias Fey, Aldo R Boccaccini, Christoph Alexiou & Iwona Cicha
Pages: 1899-1915
Published online: 28 Mar 2018
AbstractforDextran-coated superparamagnetic iron oxide nanoparticles for magnetic resonance imaging: evaluation of size-dependent imaging properties, storage stability and safety | Full Text | References | PDF (2 MB)
  • 267 Views
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Article
Development of dihydrochalcone-functionalized gold nanoparticles for augmented antineoplastic activity
Jason N Payne, Vivek D Badwaik, Hitesh K Waghwani, Harsh V Moolani, Sarah Tockstein, David H Thompson & Rajalingam Dakshinamurthy
Pages: 1917-1926
Published online: 28 Mar 2018
AbstractforDevelopment of dihydrochalcone-functionalized gold nanoparticles for augmented antineoplastic activity | Full Text | References | PDF (1.4 MB)
  • 87 Views
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Article
Antibody-modified liposomes for tumor-targeting delivery of timosaponin AIII
Lu Lu, Yue Ding, Yong Zhang, Rodney JY Ho, Yuan Zhao, Tong Zhang & Chunrong Guo
Pages: 1927-1944
Published online: 29 Mar 2018
AbstractforAntibody-modified liposomes for tumor-targeting delivery of timosaponin AIII | Full Text | References | PDF (3.9 MB)
  • 136 Views
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Article
RETRACTED ARTICLE: In vitro/vivo drug release and anti-diabetic cardiomyopathy properties of curcumin/PBLG-PEG-PBLG nanoparticles
Fei Tong, Rongkui Chai, Haiying Jiang & Bo Dong
Pages: 1945-1962
Published online: 03 Apr 2018
AbstractforRETRACTED ARTICLE: In vitro/vivo drug release and anti-diabetic cardiomyopathy properties of curcumin/PBLG-PEG-PBLG nanoparticles | PDF (2.6 MB)
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Review

Review Article
Nanomedicine applications in women’s health: state of the art
Oliver Lloyd-Parry, Charlotte Downing, Eisa Aleisaei, Celine Jones & Kevin Coward
Pages: 1963-1983
Published online: 29 Mar 2018
AbstractforNanomedicine applications in women’s health: state of the art | Full Text | References | PDF (1.3 MB)
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Original Research

Article
The 95RGD97 sequence on the Aα chain of fibrinogen is essential for binding to its erythrocyte receptor
Filomena A Carvalho, Ana Filipa Guedes, Cedric Duval, Fraser L Macrae, Luke Swithenbank, David H Farrell, Robert AS Ariëns & Nuno C Santos
Pages: 1985-1992
Published online: 03 Apr 2018
AbstractforThe 95RGD97 sequence on the Aα chain of fibrinogen is essential for binding to its erythrocyte receptor | Full Text | References | PDF (3.5 MB)
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Article
Nanoselenium prevents eimeriosis-induced inflammation and regulates mucin gene expression in mice jejunum
Abdulsalam A Alkhudhayri, Mohamed A Dkhil & Saleh Al-Quraishy
Pages: 1993-2003
Published online: 03 Apr 2018
AbstractforNanoselenium prevents eimeriosis-induced inflammation and regulates mucin gene expression in mice jejunum | Full Text | References | PDF (12 MB)
  • 100 Views
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Article
Inhibition of H1N1 influenza virus-induced apoptosis by functionalized selenium nanoparticles with amantadine through ROS-mediated AKT signaling pathways
Yinghua Li, Zhengfang Lin, Min Guo, Mingqi Zhao, Yu Xia, Changbing Wang, Tiantian Xu & Bing Zhu
Pages: 2005-2016
Published online: 03 Apr 2018
AbstractforInhibition of H1N1 influenza virus-induced apoptosis by functionalized selenium nanoparticles with amantadine through ROS-mediated AKT signaling pathways | Full Text | References | PDF (5.3 MB)
  • 140 Views
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Article
AlPcS4-PDT for gastric cancer therapy using gold nanorod, cationic liposome, and Pluronic® F127 nanomicellar drug carriers
Jing Xin, Sijia Wang, Bing Wang, Jiazhuang Wang, Jing Wang, Luwei Zhang, Bo Xin, Lijian Shen, Zhenxi Zhang & Cuiping Yao
Pages: 2017-2036
Published online: 04 Apr 2018
AbstractforAlPcS4-PDT for gastric cancer therapy using gold nanorod, cationic liposome, and Pluronic® F127 nanomicellar drug carriers | Full Text | References | PDF (3.8 MB)
  • 113 Views
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Article
Effects of hydrogenated TiO2 nanotube arrays on protein adsorption and compatibility with osteoblast-like cells
Ran Lu, Caiyun Wang, Xin Wang, Yuji Wang, Na Wang, Joshua Chou, Tao Li, Zhenting Zhang, Yunhan Ling & Su Chen
Pages: 2037-2049
Published online: 04 Apr 2018
AbstractforEffects of hydrogenated TiO2 nanotube arrays on protein adsorption and compatibility with osteoblast-like cells | Full Text | References | PDF (3.1 MB)
  • 86 Views
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Article
Fabrication of a triptolide-loaded and poly-γ-glutamic acid-based amphiphilic nanoparticle for the treatment of rheumatoid arthritis
Li Zhang, Junli Chang, Yongjian Zhao, Hao Xu, Tengteng Wang, Qiang Li, Lianping Xing, Jing Huang, Yongjun Wang & Qianqian Liang
Pages: 2051-2064
Published online: 04 Apr 2018
AbstractforFabrication of a triptolide-loaded and poly-γ-glutamic acid-based amphiphilic nanoparticle for the treatment of rheumatoid arthritis | Full Text | References | PDF (3 MB)
  • 114 Views
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Article
Colloidal plasmonic gold nanoparticles and gold nanorings: shape-dependent generation of singlet oxygen and their performance in enhanced photodynamic cancer therapy
Yamin Yang, Yue Hu, Henry Du, Lei Ren & Hongjun Wang
Pages: 2065-2078
Published online: 05 Apr 2018
AbstractforColloidal plasmonic gold nanoparticles and gold nanorings: shape-dependent generation of singlet oxygen and their performance in enhanced photodynamic cancer therapy | Full Text | References | PDF (4.4 MB)
  • 80 Views
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Article
Cellular interaction of a layer-by-layer based drug delivery system depending on material properties and cell types
Mandy Brueckner, Steffen Jankuhn, Eva-Maria Jülke & Uta Reibetanz
Pages: 2079-2091
Published online: 05 Apr 2018
AbstractforCellular interaction of a layer-by-layer based drug delivery system depending on material properties and cell types | Full Text | References | PDF (4.3 MB)
  • 61 Views
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Article
Role of Au(NPs) in the enhanced response of Au(NPs)-decorated MWCNT electrochemical biosensor
Shahid Mehmood, Regina Ciancio, Elvio Carlino & Arshad S Bhatti
Pages: 2093-2106
Published online: 17 Apr 2018
AbstractforRole of Au(NPs) in the enhanced response of Au(NPs)-decorated MWCNT electrochemical biosensor | Full Text | References | PDF (2.9 MB)
  • 135 Views
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Review

Review Article
Nano-selenium and its nanomedicine applications: a critical review
Bozena Hosnedlova, Marta Kepinska, Sylvie Skalickova, Carlos Fernandez, Branislav Ruttkay-Nedecky, Qiuming Peng, Mojmir Baron, Magdalena Melcova, Radka Opatrilova, Jarmila Zidkova, Geir Bjørklund, Jiri Sochor & Rene Kizek
Pages: 2107-2128
Published online: 10 Apr 2018
AbstractforNano-selenium and its nanomedicine applications: a critical review | Full Text | References | PDF (1.2 MB)
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Original Research

Article
Preparation, characterization and systemic application of self-assembled hydroxyethyl starch nanoparticles-loaded flavonoid Morin for hyperuricemia therapy
Jianbo Li, Yang Yang, Likang Lu, Qiujin Ma & Jinjie Zhang
Pages: 2129-2141
Published online: 10 Apr 2018
AbstractforPreparation, characterization and systemic application of self-assembled hydroxyethyl starch nanoparticles-loaded flavonoid Morin for hyperuricemia therapy | Full Text | References | PDF (4.8 MB)
  • 137 Views
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Article
Cantharidin-encapsulated thermal-sensitive liposomes coated with gold nanoparticles for enhanced photothermal therapy on A431 cells
Sijia Wang, Jing Xin, Luwei Zhang, Yicheng Zhou, Cuiping Yao, Bing Wang, Jing Wang & Zhenxi Zhang
Pages: 2143-2160
Published online: 10 Apr 2018
AbstractforCantharidin-encapsulated thermal-sensitive liposomes coated with gold nanoparticles for enhanced photothermal therapy on A431 cells | Full Text | References | PDF (5.7 MB)
  • 114 Views
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Article
Dual-responsive dithio-polydopamine coated porous CeO2 nanorods for targeted and synergistic drug delivery
Ying Zhang, Xiaowen Wu, Chenxi Hou, Kun Shang, Kui Yang, Zhimin Tian, Zhichao Pei, Yongquan Qu & Yuxin Pei
Pages: 2161-2173
Published online: 12 Apr 2018
AbstractforDual-responsive dithio-polydopamine coated porous CeO2 nanorods for targeted and synergistic drug delivery | Full Text | References | PDF (3.8 MB)
  • 203 Views
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Article
Improved osseointegration properties of hierarchical microtopographic/nanotopographic coatings fabricated on titanium implants
Elena G Zemtsova, Natalia M Yudintceva, Pavel E Morozov, Ruslan Z Valiev, Vladimir M Smirnov & Maxim A Shevtsov
Pages: 2175-2188
Published online: 11 Apr 2018
AbstractforImproved osseointegration properties of hierarchical microtopographic/nanotopographic coatings fabricated on titanium implants | Full Text | References | PDF (3 MB)
  • 59 Views
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Article
A comparative in vivo study of strontium-functionalized and SLActive™ implant surfaces in early bone healing
Vincent Offermanns, Ole Z Andersen, Michael Sillassen, Klaus P Almtoft, Inge H Andersen, Frank Kloss & Morten Foss
Pages: 2189-2197
Published online: 11 Apr 2018
AbstractforA comparative in vivo study of strontium-functionalized and SLActive™ implant surfaces in early bone healing | Full Text | References | PDF (8.9 MB)
  • 87 Views
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Article
Difunctional bacteriophage conjugated with photosensitizers for Candida albicans-targeting photodynamic inactivation
Shuai Dong, Hongxi Shi, Xintong Zhang, Xi Chen, Donghui Cao, Chuanbin Mao, Xiang Gao & Li Wang
Pages: 2199-2216
Published online: 11 Apr 2018
AbstractforDifunctional bacteriophage conjugated with photosensitizers for Candida albicans-targeting photodynamic inactivation | Full Text | References | PDF (12.2 MB)
  • 95 Views
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Review

Review Article
Antimicrobial hydrogels: promising materials for medical application
Kerong Yang, Qing Han, Bingpeng Chen, Yuhao Zheng, Kesong Zhang, Qiang Li & Jincheng Wang
Pages: 2217-2263
Published online: 12 Apr 2018
AbstractforAntimicrobial hydrogels: promising materials for medical application | Full Text | References | PDF (4.4 MB)
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Original Research

Article
Tanshinol borneol ester on nanostructured lipid carriers has longer brain and systemic effector retention and better antioxidant activity in vivo
Xinyi Yuan, Fuhuan Fei, Huanmei Sun, Chaoni Xiao, Xinfeng Zhao, Yajun Zhang & Xiaohui Zheng
Pages: 2265-2274
Published online: 12 Apr 2018
AbstractforTanshinol borneol ester on nanostructured lipid carriers has longer brain and systemic effector retention and better antioxidant activity in vivo | Full Text | References | PDF (1,009.4 KB)
  • 81 Views
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Retraction

Retraction
Controlled-release and preserved bioactivity of proteins from (self-assembled) core-shell double-walled microspheres [Retraction]
Page: 2275
Published online: 28 Feb 2023
CitationforControlled-release and preserved bioactivity of proteins from (self-assembled) core-shell double-walled microspheres [Retraction] | Full Text | PDF (138.5 KB)
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Retraction
Preparation of bioactive interferon alpha–loaded polysaccharide nanoparticles using a new approach of temperature-induced water phase/water-phase emulsion [Retraction]
Page: 2277
Published online: 19 Apr 2018
CitationforPreparation of bioactive interferon alpha–loaded polysaccharide nanoparticles using a new approach of temperature-induced water phase/water-phase emulsion [Retraction] | Full Text | PDF (134.6 KB)
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Original Research

Article
Silica nanoparticle-induced oxidative stress and mitochondrial damage is followed by activation of intrinsic apoptosis pathway in glioblastoma cells
Magdalena Kusaczuk, Rafał Krętowski, Monika Naumowicz, Anna Stypułkowska & Marzanna Cechowska-Pasko
Pages: 2279-2294
Published online: 12 Apr 2018
AbstractforSilica nanoparticle-induced oxidative stress and mitochondrial damage is followed by activation of intrinsic apoptosis pathway in glioblastoma cells | Full Text | References | PDF (5.6 MB)
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Article
RETRACTED ARTICLE: miR-221 suppression through nanoparticle-based miRNA delivery system for hepatocellular carcinoma therapy and its diagnosis as a potential biomarker
Feng Li, Feiran Wang, Changlai Zhu, Qun Wei, Tianyi Zhang & You Lang Zhou
Pages: 2295-2307
Published online: 13 Apr 2018
AbstractforRETRACTED ARTICLE: miR-221 suppression through nanoparticle-based miRNA delivery system for hepatocellular carcinoma therapy and its diagnosis as a potential biomarker | PDF (4.7 MB)
  • 34 Views
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Article
Efficient gene transfection to the brain with ultrasound irradiation in mice using stabilized bubble lipopolyplexes prepared by the surface charge regulation method
Koki Ogawa, Yuki Fuchigami, Masayori Hagimori, Shintaro Fumoto, Yusuke Miura & Shigeru Kawakami
Pages: 2309-2320
Published online: 16 Apr 2018
AbstractforEfficient gene transfection to the brain with ultrasound irradiation in mice using stabilized bubble lipopolyplexes prepared by the surface charge regulation method | Full Text | References | PDF (5.5 MB)
  • 73 Views
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Review

Review Article
Global trends in nanomedicine research on triple negative breast cancer: a bibliometric analysis
Ramon Handerson Gomes Teles, Herick Fernando Moralles & Márcia Regina Cominetti
Pages: 2321-2336
Published online: 17 Apr 2018
AbstractforGlobal trends in nanomedicine research on triple negative breast cancer: a bibliometric analysis | Full Text | References | PDF (2.3 MB)
  • 390 Views
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Article
Sensitive determination of dopamine levels via surface-enhanced Raman scattering of Ag nanoparticle dimers
Xiantong Yu, XiaoXiao He, Taiqun Yang, Litao Zhao, Qichen Chen, Sanjun Zhang, Jinquan Chen & Jianhua Xu
Pages: 2337-2347
Published online: 17 Apr 2018
AbstractforSensitive determination of dopamine levels via surface-enhanced Raman scattering of Ag nanoparticle dimers | Full Text | References | PDF (2.6 MB)
  • 85 Views
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Article
In vivo antimicrobial activity of silver nanoparticles produced via a green chemistry synthesis using Acacia rigidula as a reducing and capping agent
Carlos Enrique Escárcega-González, JA Garza-Cervantes, A Vázquez-Rodríguez, Liliana Zulem Montelongo-Peralta, MT Treviño-González, E Díaz Barriga Castro, EM Saucedo-Salazar, RM Chávez Morales, DI Regalado Soto, FM Treviño González, JL Carrazco Rosales, Rocío Villalobos Cruz & José Rubén Morones-Ramírez
Pages: 2349-2363
Published online: 28 Feb 2023
AbstractforIn vivo antimicrobial activity of silver nanoparticles produced via a green chemistry synthesis using Acacia rigidula as a reducing and capping agent | Full Text | References | PDF (4.4 MB)
  • 518 Views
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Article
Characterization and evaluation of graphene oxide scaffold for periodontal wound healing of class II furcation defects in dog
Kohei Kawamoto, Hirofumi Miyaji, Erika Nishida, Saori Miyata, Akihito Kato, Akito Tateyama, Tomokazu Furihata, Kanako Shitomi, Toshihiko Iwanaga & Tsutomu Sugaya
Pages: 2365-2376
Published online: 18 Apr 2018
AbstractforCharacterization and evaluation of graphene oxide scaffold for periodontal wound healing of class II furcation defects in dog | Full Text | References | PDF (6.9 MB)
  • 120 Views
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Article
Curdlan sulfate–O-linked quaternized chitosan nanoparticles: potential adjuvants to improve the immunogenicity of exogenous antigens via intranasal vaccination
Shu Zhang, Shengshi Huang, Lu Lu, Xinlei Song, Pingli Li & Fengshan Wang
Pages: 2377-2394
Published online: 18 Apr 2018
AbstractforCurdlan sulfate–O-linked quaternized chitosan nanoparticles: potential adjuvants to improve the immunogenicity of exogenous antigens via intranasal vaccination | Full Text | References | PDF (5 MB)
  • 119 Views
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Article
Colon-specific pulsatile drug release provided by electrospun shellac nanocoating on hydrophilic amorphous composites
Yao-Yao Yang, Zhe-Peng Liu, Deng-Guang Yu, Ke Wang, Ping Liu & Xiaohong Chen
Pages: 2395-2404
Published online: 18 Apr 2018
AbstractforColon-specific pulsatile drug release provided by electrospun shellac nanocoating on hydrophilic amorphous composites | Full Text | References | PDF (2.5 MB)
  • 141 Views
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Article
Smart polymeric nanoparticles with pH-responsive and PEG-detachable properties for co-delivering paclitaxel and survivin siRNA to enhance antitumor outcomes
Mingji Jin, Guangming Jin, Lin Kang, Liqing Chen, Zhonggao Gao & Wei Huang
Pages: 2405-2426
Published online: 20 Apr 2018
AbstractforSmart polymeric nanoparticles with pH-responsive and PEG-detachable properties for co-delivering paclitaxel and survivin siRNA to enhance antitumor outcomes | Full Text | References | PDF (4.7 MB)
  • 173 Views
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Article
Combined use of fluorescence with a magnetic tracer and dilution effect upon sentinel node localization in a murine model
Akihiro Kuwahata, Muneer Ahmed, Kohei Saeki, Shinichi Chikaki, Miki Kaneko, Wenqi Qiu, Zonghao Xin, Shinji Yamaguchi, Akiko Kaneko, Michael Douek, Moriaki Kusakabe & Masaki Sekino
Pages: 2427-2433
Published online: 19 Apr 2018
AbstractforCombined use of fluorescence with a magnetic tracer and dilution effect upon sentinel node localization in a murine model | Full Text | References | PDF (1 MB)
  • 46 Views
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Article
Evaluation of the potential of a simplified co-delivery system with oligodeoxynucleotides as a drug carrier for enhanced antitumor effect
Chunxi Liu, Tingxian Liu, Yongjun Liu & Na Zhang
Pages: 2435-2445
Published online: 20 Apr 2018
AbstractforEvaluation of the potential of a simplified co-delivery system with oligodeoxynucleotides as a drug carrier for enhanced antitumor effect | Full Text | References | PDF (2 MB)
  • 42 Views
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Article
Biological responses to core–shell-structured Fe3O4@SiO2-NH2 nanoparticles in rats by a nuclear magnetic resonance-based metabonomic strategy
Zhongxue Yuan, Rui Xu, Jinquan Li, Yueli Chen, Binghui Wu, Jianghua Feng & Zhong Chen
Pages: 2447-2462
Published online: 23 Apr 2018
AbstractforBiological responses to core–shell-structured Fe3O4@SiO2-NH2 nanoparticles in rats by a nuclear magnetic resonance-based metabonomic strategy | Full Text | References | PDF (2.9 MB)
  • 65 Views
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Article
Preparation, characterization, in vitro and in vivo anti-tumor effect of thalidomide nanoparticles on lung cancer
Long Xia Chen, Xiao Ling Ni, Heng Zhang, Min Wu, Jing Liu, Shan Xu, Ling Lin Yang, Shao Zhi Fu & Jingbo Wu
Pages: 2463-2476
Published online: 23 Apr 2018
AbstractforPreparation, characterization, in vitro and in vivo anti-tumor effect of thalidomide nanoparticles on lung cancer | Full Text | References | PDF (2.7 MB)
  • 122 Views
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Article
Amyloid-like staining property of RADA16-I nanofibers and its potential application in detecting and imaging the nanomaterial
Yongzhu Chen, Yusi Hua, Wensheng Zhang, Chengkang Tang, Yan Wang, Yujun Zhang & Feng Qiu
Pages: 2477-2489
Published online: 28 Feb 2023
AbstractforAmyloid-like staining property of RADA16-I nanofibers and its potential application in detecting and imaging the nanomaterial | Full Text | References | PDF (7.1 MB)
  • 91 Views
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Article
Fe3O4@Au composite magnetic nanoparticles modified with cetuximab for targeted magneto-photothermal therapy of glioma cells
Qianling Lu, Xinyu Dai, Peng Zhang, Xiao Tan, Yuejiao Zhong, Cheng Yao, Mei Song, Guili Song, Zhenghai Zhang, Gang Peng, Zhirui Guo, Yaoqi Ge, Kangzhen Zhang & Yuntao Li
Pages: 2491-2505
Published online: 23 Apr 2018
AbstractforFe3O4@Au composite magnetic nanoparticles modified with cetuximab for targeted magneto-photothermal therapy of glioma cells | Full Text | References | PDF (15.5 MB)
  • 172 Views
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Article
Endogenous ornithine decarboxylase/polyamine system mediated the antagonist role of insulin/PEG-CMCS preconditioning against heart ischemia/reperfusion injury in diabetes mellitus
Fei Tong, Suhuan Liu, Bing Yan, Xuejun Li, Shiwei Ruan & Shuyu Yang
Pages: 2507-2520
Published online: 23 Apr 2018
AbstractforEndogenous ornithine decarboxylase/polyamine system mediated the antagonist role of insulin/PEG-CMCS preconditioning against heart ischemia/reperfusion injury in diabetes mellitus | Full Text | References | PDF (1.9 MB)
  • 64 Views
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Article
Gold nanoparticle-based colorimetric method for the detection of prostate-specific antigen
Ning Xia, Dehua Deng, Yiru Wang, Chao Fang & Su-Juan Li
Pages: 2521-2530
Published online: 28 Feb 2023
AbstractforGold nanoparticle-based colorimetric method for the detection of prostate-specific antigen | Full Text | References | PDF (1.6 MB)
  • 122 Views
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Article
Methyl-β-cyclodextrin quaternary ammonium chitosan conjugate: nanoparticles vs macromolecular soluble complex
Anna Maria Piras, Angela Fabiano, Federica Chiellini & Ylenia Zambito
Pages: 2531-2541
Published online: 24 Apr 2018
AbstractforMethyl-β-cyclodextrin quaternary ammonium chitosan conjugate: nanoparticles vs macromolecular soluble complex | Full Text | References | PDF (933.8 KB)
  • 66 Views
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Article
Nanosized titanium dioxide-induced premature ovarian failure is associated with abnormalities in serum parameters in female mice
Fashui Hong & Ling Wang
Pages: 2543-2549
Published online: 27 Apr 2018
AbstractforNanosized titanium dioxide-induced premature ovarian failure is associated with abnormalities in serum parameters in female mice | Full Text | References | PDF (2.9 MB)
  • 93 Views
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Article
Peptide-functionalized quantum dots for potential applications in the imaging and treatment of obesity
Ntevheleni Thovhogi, Nicole Remaliah Samantha Sibuyi, Martin Opiyo Onani, Mervin Meyer & Abram Madimabe Madiehe
Pages: 2551-2559
Published online: 27 Apr 2018
AbstractforPeptide-functionalized quantum dots for potential applications in the imaging and treatment of obesity | Full Text | References | PDF (1.7 MB)
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Article
Arginine, glycine, aspartic acid peptide-modified paclitaxel and curcumin co-loaded liposome for the treatment of lung cancer: in vitro/vivo evaluation
Kanqiu Jiang, Mingjing Shen & Weihua Xu
Pages: 2561-2569
Published online: 28 Feb 2023
AbstractforArginine, glycine, aspartic acid peptide-modified paclitaxel and curcumin co-loaded liposome for the treatment of lung cancer: in vitro/vivo evaluation | Full Text | References | PDF (2.2 MB)
  • 166 Views
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Article
Development of nanoemulsion for efficient brain parenteral delivery of cefuroxime: designs, characterizations, and pharmacokinetics
Siti Norhawani Harun, Syafinaz Amin Nordin, Siti Salwa Abd Gani, Ahmad Fuad Shamsuddin, Mahiran Basri & Hamidon Bin Basri
Pages: 2571-2584
Published online: 28 Feb 2023
AbstractforDevelopment of nanoemulsion for efficient brain parenteral delivery of cefuroxime: designs, characterizations, and pharmacokinetics | Full Text | References | PDF (1.3 MB)
  • 312 Views
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Article
Glypican-1-antibody-conjugated Gd–Au nanoclusters for FI/MRI dual-modal targeted detection of pancreatic cancer
Xin Huang, Chengqi Fan, Huanhuan Zhu, Wenjun Le, Shaobin Cui, Xin Chen, Wei Li, Fulei Zhang, Yong Huang, Donglu Sh, Zheng Cui, Chengwei Shao & Bingdi Chen
Pages: 2585-2599
Published online: 30 Apr 2018
AbstractforGlypican-1-antibody-conjugated Gd–Au nanoclusters for FI/MRI dual-modal targeted detection of pancreatic cancer | Full Text | References | PDF (4.3 MB)
  • 67 Views
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Article
Protection of silver nanoparticles using Eysenhardtia polystachya in peroxide-induced pancreatic β-Cell damage and their antidiabetic properties in zebrafish
Abraham Heriberto Garcia Campoy, Rosa Martha Perez Gutierrez, Gabriela Manriquez-Alvirde & Alethia Muñiz Ramirez
Pages: 2601-2612
Published online: 01 May 2018
AbstractforProtection of silver nanoparticles using Eysenhardtia polystachya in peroxide-induced pancreatic β-Cell damage and their antidiabetic properties in zebrafish | Full Text | References | PDF (1.3 MB)
  • 277 Views
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Article
DNA- and RNA-binding ability of oligoDapT, a nucleobase-decorated peptide, for biomedical applications
Domenica Musumeci, Valentina Roviello & Giovanni N Roviello
Pages: 2613-2629
Published online: 01 May 2018
AbstractforDNA- and RNA-binding ability of oligoDapT, a nucleobase-decorated peptide, for biomedical applications | Full Text | References | PDF (4 MB)
  • 77 Views
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Article
Physiologically based pharmacokinetic modeling of nanoceria systemic distribution in rats suggests dose- and route-dependent biokinetics
Ulrika Carlander, Tshepo Paulsen Moto, Anteneh Assefa Desalegn, Robert A Yokel & Gunnar Johanson
Pages: 2631-2646
Published online: 01 May 2018
AbstractforPhysiologically based pharmacokinetic modeling of nanoceria systemic distribution in rats suggests dose- and route-dependent biokinetics | Full Text | References | PDF (3.8 MB)
  • 143 Views
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Article
Silver nanoparticles induced alterations in multiple cellular targets, which are critical for drug susceptibilities and pathogenicity in fungal pathogen (Candida albicans)
Venkatraman Srinivasan Radhakrishnan, Mohana Krishna Reddy Mudiam, Manish Kumar, Surya Prakash Dwivedi, Surinder Pal Singh & Tulika Prasad
Pages: 2647-2663
Published online: 03 May 2018
AbstractforSilver nanoparticles induced alterations in multiple cellular targets, which are critical for drug susceptibilities and pathogenicity in fungal pathogen (Candida albicans) | Full Text | References | PDF (3.9 MB)
  • 401 Views
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Article
Nanostructured Ag+-substituted fluorhydroxyapatite-TiO2 coatings for enhanced bactericidal effects and osteoinductivity of Ti for biomedical applications
Yong Huang, Guiqin Song, Xiaotong Chang, Zhenhui Wang, Xuejiao Zhang, Shuguang Han, Zhuobin Su, Hejie Yang, Dongdong Yang & Xiaojun Zhang
Pages: 2665-2684
Published online: 03 May 2018
AbstractforNanostructured Ag+-substituted fluorhydroxyapatite-TiO2 coatings for enhanced bactericidal effects and osteoinductivity of Ti for biomedical applications | Full Text | References | PDF (10.2 MB)
  • 106 Views
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Article
In vivo investigation on the chronic hepatotoxicity induced by intraperitoneal administration of 10-nm silicon dioxide nanoparticles
Mansour Almansour, Saud Alarifi & Bashir Jarrar
Pages: 2685-2696
Published online: 07 May 2018
AbstractforIn vivo investigation on the chronic hepatotoxicity induced by intraperitoneal administration of 10-nm silicon dioxide nanoparticles | Full Text | References | PDF (1.4 MB)
  • 116 Views
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Article
Synergistic antifungal effect of chitosan-stabilized selenium nanoparticles synthesized by pulsed laser ablation in liquids against Candida albicans biofilms
Humberto H Lara, Gregory Guisbiers, Jonathan Mendoza, Lawrence C Mimun, Brandy A Vincent, Jose L Lopez-Ribot & Kelly L Nash
Pages: 2697-2708
Published online: 03 May 2018
AbstractforSynergistic antifungal effect of chitosan-stabilized selenium nanoparticles synthesized by pulsed laser ablation in liquids against Candida albicans biofilms | Full Text | References | PDF (3.8 MB)
  • 298 Views
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Review

Review Article
Nanoparticle-mediated drug delivery to treat infections in the female reproductive tract: evaluation of experimental systems and the potential for mathematical modeling
Lee B Sims, Hermann B Frieboes & Jill M Steinbach-Rankins
Pages: 2709-2727
Published online: 28 Feb 2023
AbstractforNanoparticle-mediated drug delivery to treat infections in the female reproductive tract: evaluation of experimental systems and the potential for mathematical modeling | Full Text | References | PDF (850.5 KB)
  • 92 Views
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Review Article
Dysfunction of various organelles provokes multiple cell death after quantum dot exposure
Yan Wang & Meng Tang
Pages: 2729-2742
Published online: 07 May 2018
AbstractforDysfunction of various organelles provokes multiple cell death after quantum dot exposure | Full Text | References | PDF (2.2 MB)
  • 97 Views
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Original Research

Article
Protein delivery nanosystem of six-arm copolymer poly(ε-caprolactone)–poly(ethylene glycol) for long-term sustained release
Jianwei Duan, Chao Liu, Xiaoyu Liang, Xuanling Li, Youlu Chen, Zuoguan Chen, Xiaoli Wang, Deling Kong, Yongjun Li & Jing Yang
Pages: 2743-2754
Published online: 08 May 2018
AbstractforProtein delivery nanosystem of six-arm copolymer poly(ε-caprolactone)–poly(ethylene glycol) for long-term sustained release | Full Text | References | PDF (3 MB)
  • 69 Views
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Article
Remineralization potential of nano-hydroxyapatite on enamel and cementum surrounding margin of computer-aided design and computer-aided manufacturing ceramic restoration
Niwut Juntavee, Apa Juntavee & Preeyarat Plongniras
Pages: 2755-2765
Published online: 08 May 2018
AbstractforRemineralization potential of nano-hydroxyapatite on enamel and cementum surrounding margin of computer-aided design and computer-aided manufacturing ceramic restoration | Full Text | References | PDF (12.2 MB)
  • 127 Views
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Review

Review Article
Impact of nanoparticles on neuron biology: current research trends
Firdos Alam Khan, Dana Almohazey, Munthar Alomari & Sarah Ameen Almofty
Pages: 2767-2776
Published online: 09 May 2018
AbstractforImpact of nanoparticles on neuron biology: current research trends | Full Text | References | PDF (627.8 KB)
  • 198 Views
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Article
Development and blood compatibility assessment of electrospun polyvinyl alcohol blended with metallocene polyethylene and plectranthus amboinicus (PVA/mPE/PA) for bone tissue engineering
Jie Qi, Huang Zhang, Yingzhou Wang, Mohan Prasath Mani & Saravana Kumar Jaganathan
Pages: 2777-2788
Published online: 11 May 2018
AbstractforDevelopment and blood compatibility assessment of electrospun polyvinyl alcohol blended with metallocene polyethylene and plectranthus amboinicus (PVA/mPE/PA) for bone tissue engineering | Full Text | References | PDF (5.1 MB)
  • 113 Views
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Article
SN38-loaded <100 nm targeted liposomes for improving poor solubility and minimizing burst release and toxicity: in vitro and in vivo study
Yi-Ping Fang, Chih-Hung Chuang, Yi-Jhun Wu, Hsin-Che Lin & Yun-Chi Lu
Pages: 2789-2802
Published online: 10 May 2018
AbstractforSN38-loaded <100 nm targeted liposomes for improving poor solubility and minimizing burst release and toxicity: in vitro and in vivo study | Full Text | References | PDF (1.9 MB)
  • 128 Views
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Article
Near-infrared light-mediated photodynamic/photothermal therapy nanoplatform by the assembly of Fe3O4 carbon dots with graphitic black phosphorus quantum dots
Ming Zhang, Wentao Wang, Yingjun Cui, Ninglin Zhou & Jian Shen
Pages: 2803-2819
Published online: 10 May 2018
AbstractforNear-infrared light-mediated photodynamic/photothermal therapy nanoplatform by the assembly of Fe3O4 carbon dots with graphitic black phosphorus quantum dots | Full Text | References | PDF (4.5 MB)
  • 205 Views
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Article
The protective role of quercetin and arginine on gold nanoparticles induced hepatotoxicity in rats
Mohamed Anwar K Abdelhalim, Sherif A Abdelmottaleb Moussa & Huda Abdo Yahya Qaid
Pages: 2821-2825
Published online: 11 May 2018
AbstractforThe protective role of quercetin and arginine on gold nanoparticles induced hepatotoxicity in rats | Full Text | References | PDF (632.5 KB)
  • 109 Views
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Article
Development and characterization of a nanoemulsion containing propranolol for topical delivery
Tatiana Zanela da Silva Marques, Ralph Santos-Oliveira, Luciana Betzler de Oliveira de Siqueira, Verônica da Silva Cardoso, Zaida Maria Faria de Freitas, Rita de Cássia da Silva Ascenção Barros, Ana Lúcia Vazquez Villa, Mariana Sato de Souza de Bustamante Monteiro, Elisabete Pereira dos Santos & Eduardo Ricci-Junior
Pages: 2827-2837
Published online: 14 May 2018
AbstractforDevelopment and characterization of a nanoemulsion containing propranolol for topical delivery | Full Text | References | PDF (1.1 MB)
  • 321 Views
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Article
Mechanistic insight into the interaction of gastrointestinal mucus with oral diblock copolymers synthesized via ATRP method
Jiao Liu, Jie Cao, Jianhua Cao, Shangcong Han, Yan Liang, Mingfeng Bai & Yong Sun
Pages: 2839-2856
Published online: 15 May 2018
AbstractforMechanistic insight into the interaction of gastrointestinal mucus with oral diblock copolymers synthesized via ATRP method | Full Text | References | PDF (6.2 MB)
  • 57 Views
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Article
Responses of intestinal virome to silver nanoparticles: safety assessment by classical virology, whole-genome sequencing and bioinformatics approaches
Kuppan Gokulan, Aschalew Z Bekele, Kenneth L Drake & Sangeeta Khare
Pages: 2857-2867
Published online: 16 May 2018
AbstractforResponses of intestinal virome to silver nanoparticles: safety assessment by classical virology, whole-genome sequencing and bioinformatics approaches | Full Text | References | PDF (2.2 MB)
  • 119 Views
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Article
Formulation and evaluation of mixed polymeric micelles of quercetin for treatment of breast, ovarian, and multidrug resistant cancers
Arjun Patra, Swaha Satpathy, Anitha K Shenoy, Jason A Bush, Mohsin Kazi & Muhammad Delwar Hussain
Pages: 2869-2881
Published online: 16 May 2018
AbstractforFormulation and evaluation of mixed polymeric micelles of quercetin for treatment of breast, ovarian, and multidrug resistant cancers | Full Text | References | PDF (1.6 MB)
  • 354 Views
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Article
Hierarchically aligned fibrin nanofiber hydrogel accelerated axonal regrowth and locomotor function recovery in rat spinal cord injury
Shenglian Yao, Shukui Yu, Zheng Cao, Yongdong Yang, Xing Yu, Hai-Quan Mao, Lu-Ning Wang, Xiaodan Sun, Lingyun Zhao & Xiumei Wang
Pages: 2883-2895
Published online: 17 May 2018
AbstractforHierarchically aligned fibrin nanofiber hydrogel accelerated axonal regrowth and locomotor function recovery in rat spinal cord injury | Full Text | References | PDF (2.9 MB)
  • 129 Views
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Review

Review Article
Recent advances in functional nanostructures as cancer photothermal therapy
Essraa A Hussein, Moustafa M Zagho, Gheyath K Nasrallah & Ahmed A Elzatahry
Pages: 2897-2906
Published online: 17 May 2018
AbstractforRecent advances in functional nanostructures as cancer photothermal therapy | Full Text | References | PDF (628.4 KB)
  • 300 Views
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Original Research

Article
Mechanisms of oxidative stress, apoptosis, and autophagy involved in graphene oxide nanomaterial anti-osteosarcoma effect
Zhibing Tang, Lin Zhao, Zaixing Yang, Zhaohui Liu, Jia Gu, Bing Bai, Jinlian Liu, Jiaying Xu & Huilin Yang
Pages: 2907-2919
Published online: 17 May 2018
AbstractforMechanisms of oxidative stress, apoptosis, and autophagy involved in graphene oxide nanomaterial anti-osteosarcoma effect | Full Text | References | PDF (7.3 MB)
  • 141 Views
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Review Article
Stimuli-responsive polymeric micelles for drug delivery and cancer therapy
Qing Zhou, Li Zhang, TieHong Yang & Hong Wu
Pages: 2921-2942
Published online: 18 May 2018
AbstractforStimuli-responsive polymeric micelles for drug delivery and cancer therapy | Full Text | References | PDF (3.4 MB)
  • 627 Views
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Article
Elimination of mouse tumor cells from neonate spermatogonial cells utilizing cisplatin-entrapped folic acid-conjugated poly(lactic-co-glycolic acid) nanoparticles in vitro
Ronak Shabani, Mohsen Ashjari, Khadijeh Ashtari, Fariborz Izadyar, Babak Behnam, Samideh Khoei, Mohamad Asghari-Jafarabadi & Morteza Koruji
Pages: 2943-2954
Published online: 28 Feb 2023
AbstractforElimination of mouse tumor cells from neonate spermatogonial cells utilizing cisplatin-entrapped folic acid-conjugated poly(lactic-co-glycolic acid) nanoparticles in vitro | Full Text | References | PDF (4.7 MB)
  • 78 Views
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Article
Molecular study of wound healing after using biosynthesized BNC/Fe3O4 nanocomposites assisted with a bioinformatics approach
Mona Moniri, Amin Boroumand Moghaddam, Susan Azizi, Raha Abdul Rahim, Wan Zuhainis Saad, Mohammad Navaderi, Palanisamy Arulselvan & Rosfarizan Mohamad
Pages: 2955-2971
Published online: 21 May 2018
AbstractforMolecular study of wound healing after using biosynthesized BNC/Fe3O4 nanocomposites assisted with a bioinformatics approach | Full Text | References | PDF (7.8 MB)
  • 289 Views
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Review

Review Article
Properties and applications of nanoparticle/microparticle conveyors with adjuvant characteristics suitable for oral vaccination
Lei Zhang, Wendi Yang, Chaohua Hu, Qianchao Wang & Yunkun Wu
Pages: 2973-2987
Published online: 21 May 2018
AbstractforProperties and applications of nanoparticle/microparticle conveyors with adjuvant characteristics suitable for oral vaccination | Full Text | References | PDF (3.6 MB)
  • 81 Views
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Article
Airspace Dimension Assessment with nanoparticles reflects lung density as quantified by MRI
H Laura Aaltonen, Simon S Kindvall, Jonas K Jakobsson, Jakob Löndahl, Lars E Olsson, Sandra Diaz, Sophia Zackrisson & Per Wollmer
Pages: 2989-2995
Published online: 21 May 2018
AbstractforAirspace Dimension Assessment with nanoparticles reflects lung density as quantified by MRI | Full Text | References | PDF (1.2 MB)
  • 55 Views
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Article
Bilirubin detoxification using different phytomaterials: characterization and in vitro studies
Betty Titus Mathew, Shaima Raji, Sawsan Dagher, Ali Hilal-Alnaqbi, Abdel-Hamid Ismail Mourad, Sulaiman Al-Zuhair, Mahmoud Al Ahmad, Khaled Abbas El-Tarabily & Amr Amin
Pages: 2997-3010
Published online: 23 May 2018
AbstractforBilirubin detoxification using different phytomaterials: characterization and in vitro studies | Full Text | References | PDF (4.1 MB)
  • 74 Views
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Article
Dual-drug nanomedicine with hydrophilic F127-modified magnetic nanocarriers assembled in amphiphilic gelatin for enhanced penetration and drug delivery in deep tumor tissue
Yen-Ho Lai, Chih-Sheng Chiang, Tzu-Hsun Kao & San-Yuan Chen
Pages: 3011-3026
Published online: 22 May 2018
AbstractforDual-drug nanomedicine with hydrophilic F127-modified magnetic nanocarriers assembled in amphiphilic gelatin for enhanced penetration and drug delivery in deep tumor tissue | Full Text | References | PDF (4.8 MB)
  • 102 Views
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Article
High-performance reoxygenation from PLGA-PEG/PFOB emulsions: a feedback relationship between ROS and HIF-1α
Jie Wang, Ruochen Wang, Niannian Li, Xi Shen, Gang Huang, Jun Zhu & Dannong He
Pages: 3027-3038
Published online: 22 May 2018
AbstractforHigh-performance reoxygenation from PLGA-PEG/PFOB emulsions: a feedback relationship between ROS and HIF-1α | Full Text | References | PDF (3.8 MB)
  • 97 Views
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Article
Lactoferrin- and RGD-comodified, temozolomide and vincristine-coloaded nanostructured lipid carriers for gliomatosis cerebri combination therapy
Jicai Zhang, Xiang Xiao, Jianming Zhu, Ziyun Gao, Xianliang Lai, Xingen Zhu & Guohua Mao
Pages: 3039-3051
Published online: 22 May 2018
AbstractforLactoferrin- and RGD-comodified, temozolomide and vincristine-coloaded nanostructured lipid carriers for gliomatosis cerebri combination therapy | Full Text | References | PDF (4.2 MB)
  • 162 Views
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Review

Review Article
Perfluorooctylbromide nanoparticles for ultrasound imaging and drug delivery
Xiao Li, Zhongguo Sui, Xin Li, Wen Xu, Qie Guo, Jialin Sun & Fanbo Jing
Pages: 3053-3067
Published online: 25 May 2018
AbstractforPerfluorooctylbromide nanoparticles for ultrasound imaging and drug delivery | Full Text | References | PDF (5.3 MB)
  • 172 Views
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Original Research

Article
A carbon nanotube-gemcitabine-lentinan three-component composite for chemo-photothermal synergistic therapy of cancer
Ping Zhang, Wenhui Yi, Jin Hou, Sweejiang Yoo, Weiqiu Jin & Qisheng Yang
Pages: 3069-3080
Published online: 25 May 2018
AbstractforA carbon nanotube-gemcitabine-lentinan three-component composite for chemo-photothermal synergistic therapy of cancer | Full Text | References | PDF (5.5 MB)
  • 77 Views
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Article
Antimicrobial peptide-loaded liquid crystalline precursor bioadhesive system for the prevention of dental caries
Kelly Limi Aida, Paula Fernanda Kreling, Karina Sampaio Caiaffa, Giovana Maria Fioramonti Calixto, Marlus Chorilli, Denise MP Spolidorio, Norival Alves Santos-Filho, Eduardo Maffud Cilli & Cristiane Duque
Pages: 3081-3091
Published online: 25 May 2018
AbstractforAntimicrobial peptide-loaded liquid crystalline precursor bioadhesive system for the prevention of dental caries | Full Text | References | PDF (1.1 MB)
  • 144 Views
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Article
The effect of intravenous administration of liposomal curcumin in addition to sumatriptan treatment in an experimental migraine model in rats
Adriana E Bulboacă, Sorana D Bolboacă, Ioana C Stănescu, Carmen A Sfrângeu, Alina Porfire, Lucia Tefas & Angelo C Bulboacă
Pages: 3093-3103
Published online: 25 May 2018
AbstractforThe effect of intravenous administration of liposomal curcumin in addition to sumatriptan treatment in an experimental migraine model in rats | Full Text | References | PDF (1.2 MB)
  • 257 Views
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Article
Modeling the neuron as a nanocommunication system to identify spatiotemporal molecular events in neurodegenerative disease
Arunima Banerjee, Janet L Paluh, Amitava Mukherjee, K Gaurav Kumar, Archisman Ghosh & Mrinal K Naskar
Pages: 3105-3128
Published online: 25 May 2018
AbstractforModeling the neuron as a nanocommunication system to identify spatiotemporal molecular events in neurodegenerative disease | Full Text | References | PDF (2.5 MB)
  • 75 Views
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Article
A polypropylene mesh modified with poly-ε-caprolactone nanofibers in hernia repair: large animal experiment
Barbora East, Martin Plencner, Martin Kralovic, Michala Rampichova, Vera Sovkova, Karolina Vocetkova, Martin Otahal, Zbynek Tonar, Yaroslav Kolinko, Evzen Amler & Jiri Hoch
Pages: 3129-3143
Published online: 28 May 2018
AbstractforA polypropylene mesh modified with poly-ε-caprolactone nanofibers in hernia repair: large animal experiment | Full Text | References | PDF (12.4 MB)
  • 125 Views
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Review

Review Article
Advancements in the oral delivery of Docetaxel: challenges, current state-of-the-art and future trends
Muhammad Farhan Sohail, Mubashar Rehman, Hafiz Shoaib Sarwar, Sara Naveed, Omer Salman, Nadeem Irfan Bukhari, Irshad Hussain, Thomas J Webster & Gul Shahnaz
Pages: 3145-3161
Published online: 08 Jun 2018
AbstractforAdvancements in the oral delivery of Docetaxel: challenges, current state-of-the-art and future trends | Full Text | References | PDF (687 KB)
  • 337 Views
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Original Research

Article
Naked physically synthesized gold nanoparticles affect migration, mitochondrial activity, and proliferation of vascular smooth muscle cells
Huey-Ming Lo, Ming-Chieh Ma, Jiunn-Min Shieh, Hui-Ling Chen & Wen-Bin Wu
Pages: 3163-3176
Published online: 29 May 2018
AbstractforNaked physically synthesized gold nanoparticles affect migration, mitochondrial activity, and proliferation of vascular smooth muscle cells | Full Text | References | PDF (9.4 MB)
  • 64 Views
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Article
Using the interplay of magnetic guidance and controlled TGF-β release from protein-based nanocapsules to stimulate chondrogenesis
Chih-Sheng Chiang, Jian-Yi Chen, Min-Yu Chiang, Kai-Ting Hou, Wei-Ming Li, Shwu-Jen Chang & San-Yuan Chen
Pages: 3177-3188
Published online: 07 Jun 2018
AbstractforUsing the interplay of magnetic guidance and controlled TGF-β release from protein-based nanocapsules to stimulate chondrogenesis | Full Text | References | PDF (2.9 MB)
  • 69 Views
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Article
Site-specific PEGylation of an anti-CEA/CD3 bispecific antibody improves its antitumor efficacy
Haitao Pan, Jiayu Liu, Wentong Deng, Jieyu Xing, Qing Li & Zhong Wang
Pages: 3189-3201
Published online: 29 May 2018
AbstractforSite-specific PEGylation of an anti-CEA/CD3 bispecific antibody improves its antitumor efficacy | Full Text | References | PDF (3.2 MB)
  • 158 Views
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Article
Controlled release of organic–inorganic nanohybrid:cefadroxil intercalated Zn–Al-layered double hydroxide
Sher Bahadar Khan, Khalid A Alamry, Nedaa A Alyahyawi & Abdullah M Asiri
Pages: 3203-3222
Published online: 29 May 2018
AbstractforControlled release of organic–inorganic nanohybrid:cefadroxil intercalated Zn–Al-layered double hydroxide | Full Text | References | PDF (3.9 MB)
  • 117 Views
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Article
Cholesteryl oleate-loaded cationic solid lipid nanoparticles as carriers for efficient gene-silencing therapy
Marc Suñé-Pou, Silvia Prieto-Sánchez, Younes El Yousfi, Sofía Boyero-Corral, Anna Nardi-Ricart, Isaac Nofrerias-Roig, Pilar Pérez-Lozano, Encarna García-Montoya, Montserrat Miñarro-Carmona, Josep Ramón Ticó, Josep Mª Suñé-Negre, Cristina Hernández-Munain & Carlos Suñé
Pages: 3223-3233
Published online: 30 May 2018
AbstractforCholesteryl oleate-loaded cationic solid lipid nanoparticles as carriers for efficient gene-silencing therapy | Full Text | References | PDF (3 MB)
  • 87 Views
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Article
Chitosan gold nanoparticles induce cell death in HeLa and MCF-7 cells through reactive oxygen species production
Ana Carolina Martínez-Torres, Diana G Zarate-Triviño, Helen Yarimet Lorenzo-Anota, Andrea Ávila-Ávila, Carolina Rodríguez-Abrego & Cristina Rodríguez-Padilla
Pages: 3235-3250
Published online: 31 May 2018
AbstractforChitosan gold nanoparticles induce cell death in HeLa and MCF-7 cells through reactive oxygen species production | Full Text | References | PDF (4.6 MB)
  • 262 Views
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Article
A biomimetic nanoparticle-enabled toxoid vaccine against melittin
Tianyi Kang, Chenyang Li, Ting Du, Yujiao Wu, Yuping Yang, Xuan Liu, Qianqian Zhang, Xiaoping Xu & Maling Gou
Pages: 3251-3261
Published online: 01 Jun 2018
AbstractforA biomimetic nanoparticle-enabled toxoid vaccine against melittin | Full Text | References | PDF (1.7 MB)
  • 70 Views
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Article
RIPL peptide-conjugated nanostructured lipid carriers for enhanced intracellular drug delivery to hepsin-expressing cancer cells
Sang Gon Lee, Chang Hyun Kim, Si Woo Sung, Eun Seok Lee, Min Su Goh, Ho Yub Yoon, Myung Joo Kang, Sangkil Lee & Young Wook Choi
Pages: 3263-3278
Published online: 01 Jun 2018
AbstractforRIPL peptide-conjugated nanostructured lipid carriers for enhanced intracellular drug delivery to hepsin-expressing cancer cells | Full Text | References | PDF (6.7 MB)
  • 146 Views
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Article
Preparation, characterizations and anti-pollutant activity of 7,3′,4′-trihydroxyisoflavone nanoparticles in particulate matter-induced HaCaT keratinocytes
Pao-Hsien Huang, Chih-Hua Tseng, Chia-Yu Lin, Chiang-Wen Lee & Feng-Lin Yen
Pages: 3279-3293
Published online: 01 Jun 2018
AbstractforPreparation, characterizations and anti-pollutant activity of 7,3′,4′-trihydroxyisoflavone nanoparticles in particulate matter-induced HaCaT keratinocytes | Full Text | References | PDF (4 MB)
  • 100 Views
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Article
Inhibitory effect of Au@Pt-NSs on proliferation, migration, and invasion of EJ bladder carcinoma cells: involvement of cell cycle regulators, signaling pathways, and transcription factor-mediated MMP-9 expression
Seung-Shick Shin, Dae-Hwa Noh, Byungdoo Hwang, Jo-Won Lee, Sung Lyea Park, Sung-Soo Park, Bokyung Moon, Wun-Jae Kim & Sung-Kwon Moon
Pages: 3295-3310
Published online: 01 Jun 2018
AbstractforInhibitory effect of Au@Pt-NSs on proliferation, migration, and invasion of EJ bladder carcinoma cells: involvement of cell cycle regulators, signaling pathways, and transcription factor-mediated MMP-9 expression | Full Text | References | PDF (3.2 MB)
  • 63 Views
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Review

Review Article
Potential antibacterial mechanism of silver nanoparticles and the optimization of orthopedic implants by advanced modification technologies
Yun’an Qing, Lin Cheng, Ruiyan Li, Guancong Liu, Yanbo Zhang, Xiongfeng Tang, Jincheng Wang, He Liu & Yanguo Qin
Pages: 3311-3327
Published online: 05 Jun 2018
AbstractforPotential antibacterial mechanism of silver nanoparticles and the optimization of orthopedic implants by advanced modification technologies | Full Text | References | PDF (6.9 MB)
  • 1024 Views
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Original Research

Article
Enhanced oral absorption of pemetrexed by ion-pairing complex formation with deoxycholic acid derivative and multiple nanoemulsion formulations: preparation, characterization, and in vivo oral bioavailability and anticancer effect
Rudra Pangeni, Jeong Uk Choi, Vijay Kumar Panthi, Youngro Byun & Jin Woo Park
Pages: 3329-3351
Published online: 06 Jun 2018
AbstractforEnhanced oral absorption of pemetrexed by ion-pairing complex formation with deoxycholic acid derivative and multiple nanoemulsion formulations: preparation, characterization, and in vivo oral bioavailability and anticancer effect | Full Text | References | PDF (6.1 MB)
  • 162 Views
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Article
Polyethyleneimine modification of aluminum hydroxide nanoparticle enhances antigen transportation and cross-presentation of dendritic cells
Heng Dong, Zhi-Fa Wen, Lin Chen, Na Zhou, Hui Liu, Shiling Dong, Hong-ming Hu & Yongbin Mou
Pages: 3353-3365
Published online: 07 Jun 2018
AbstractforPolyethyleneimine modification of aluminum hydroxide nanoparticle enhances antigen transportation and cross-presentation of dendritic cells | Full Text | References | PDF (8.9 MB)
  • 140 Views
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Article
Morphology of a fibrin nanocoating influences dermal fibroblast behavior
Julia Pajorova, Marketa Bacakova, Jana Musilkova, Antonin Broz, Daniel Hadraba, Frantisek Lopot & Lucie Bacakova
Pages: 3367-3380
Published online: 08 Jun 2018
AbstractforMorphology of a fibrin nanocoating influences dermal fibroblast behavior | Full Text | References | PDF (8.1 MB)
  • 73 Views
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Article
Biological and osseointegration capabilities of hierarchically (meso-/micro-/nano-scale) roughened zirconia
Naser Mohammadzadeh Rezaei, Masakazu Hasegawa, Manabu Ishijima, Kourosh Nakhaei, Takahisa Okubo, Takashi Taniyama, Amirreza Ghassemi, Tania Tahsili, Wonhee Park, Makoto Hirota & Takahiro Ogawa
Pages: 3381-3395
Published online: 08 Jun 2018
AbstractforBiological and osseointegration capabilities of hierarchically (meso-/micro-/nano-scale) roughened zirconia | Full Text | References | PDF (3.9 MB)
  • 89 Views
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Review

Review Article
RNA interference: new mechanistic and biochemical insights with application in oral cancer therapy
Smaranda Buduru, Alina-Andreea Zimta, Cristina Ciocan, Cornelia Braicu, Diana Dudea, Alexandra Iulia Irimie & Ioana Berindan-Neagoe
Pages: 3397-3409
Published online: 08 Jun 2018
AbstractforRNA interference: new mechanistic and biochemical insights with application in oral cancer therapy | Full Text | References | PDF (3.7 MB)
  • 77 Views
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Original Research

Article
Bactericidal and immunomodulatory properties of magnetic nanoparticles functionalized by 1,4-dihydropyridines
Katarzyna Niemirowicz-Laskowska, Katarzyna Głuszek, Ewelina Piktel, Karlis Pajuste, Bonita Durnaś, Grzegorz Król, Agnieszka Z Wilczewska, Paul A Janmey, Aiva Plotniece & Robert Bucki
Pages: 3411-3424
Published online: 11 Jun 2018
AbstractforBactericidal and immunomodulatory properties of magnetic nanoparticles functionalized by 1,4-dihydropyridines | Full Text | References | PDF (3.1 MB)
  • 68 Views
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Article
Enhancement of surface bioactivity on carbon fiber-reinforced polyether ether ketone via graphene modification
Jin-Hong Yan, Chun-Hui Wang, Ke-Wen Li, Qi Zhang, Min Yang, Wei-Long Di-Wu, Ming Yan, Yue Song, Jing-Jing Ba, Long Bi & Yi-Sheng Han
Pages: 3425-3440
Published online: 14 Jun 2018
AbstractforEnhancement of surface bioactivity on carbon fiber-reinforced polyether ether ketone via graphene modification | Full Text | References | PDF (10.3 MB)
  • 123 Views
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Article
Zinc oxide nanoparticles induce toxicity in CAL 27 oral cancer cell lines by activating PINK1/Parkin-mediated mitophagy
Jianfeng Wang, Shutao Gao, Shuyu Wang, Zhaonan Xu & Limin Wei
Pages: 3441-3450
Published online: 28 Feb 2023
AbstractforZinc oxide nanoparticles induce toxicity in CAL 27 oral cancer cell lines by activating PINK1/Parkin-mediated mitophagy | Full Text | References | PDF (5.2 MB)
  • 176 Views
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Article
Docetaxel–trastuzumab stealth immunoliposome: development and in vitro proof of concept studies in breast cancer
Anne Rodallec, Jean-Michel Brunel, Sarah Giacometti, Helene Maccario, Florian Correard, Eric Mas, Caroline Orneto, Ariel Savina, Fanny Bouquet, Bruno Lacarelle, Joseph Ciccolini & Raphaelle Fanciullino
Pages: 3451-3465
Published online: 18 Jun 2018
AbstractforDocetaxel–trastuzumab stealth immunoliposome: development and in vitro proof of concept studies in breast cancer | Full Text | References | PDF (3.9 MB)
  • 103 Views
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Article
Codelivery of temozolomide and siRNA with polymeric nanocarrier for effective glioma treatment
Yuan Peng, Jinsheng Huang, Hong Xiao, Teng Wu & Xintao Shuai
Pages: 3467-3480
Published online: 15 Jun 2018
AbstractforCodelivery of temozolomide and siRNA with polymeric nanocarrier for effective glioma treatment | Full Text | References | PDF (3.7 MB)
  • 145 Views
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Article
Dual-layer aligned-random nanofibrous scaffolds for improving gradient microstructure of tendon-to-bone healing in a rabbit extra-articular model
Jiangyu Cai, Juan Wang, Kaiqiang Ye, Dandan Li, Chengchong Ai, Dandan Sheng, Wenhe Jin, Xingwang Liu, Yunlong Zhi, Jia Jiang, Jun Chen, Xiumei Mo & Shiyi Chen
Pages: 3481-3492
Published online: 18 Jun 2018
AbstractforDual-layer aligned-random nanofibrous scaffolds for improving gradient microstructure of tendon-to-bone healing in a rabbit extra-articular model | Full Text | References | PDF (8.1 MB)
  • 135 Views
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Article
Construction of injectable, pH sensitive, antibacterial, mineralized amino acid yolk-shell microspheres for potential minimally invasive treatment of bone infection
Zhenhua Chen, Mengen Zhao, Jie Zhang, Kang Zhou, Xiuli Ren & Xifan Mei
Pages: 3493-3506
Published online: 28 Feb 2023
AbstractforConstruction of injectable, pH sensitive, antibacterial, mineralized amino acid yolk-shell microspheres for potential minimally invasive treatment of bone infection | Full Text | References | PDF (7.1 MB)
  • 57 Views
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Article
Kidney-targeted drug delivery via rhein-loaded polyethyleneglycol-co-polycaprolactone-co-polyethylenimine nanoparticles for diabetic nephropathy therapy
Danfei Chen, Shunping Han, Yongqin Zhu, Fang Hu, Yinghui Wei & Guowei Wang
Pages: 3507-3527
Published online: 19 Jun 2018
AbstractforKidney-targeted drug delivery via rhein-loaded polyethyleneglycol-co-polycaprolactone-co-polyethylenimine nanoparticles for diabetic nephropathy therapy | Full Text | References | PDF (4.7 MB)
  • 317 Views
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Article
Nano-therapeutic cancer immunotherapy using hyperthermia-induced heat shock proteins: insights from mathematical modeling
Fang-Chu Lin, Chao-Hsiung Hsu & Yung-Ya Lin
Pages: 3529-3539
Published online: 19 Jun 2018
AbstractforNano-therapeutic cancer immunotherapy using hyperthermia-induced heat shock proteins: insights from mathematical modeling | Full Text | References | PDF (2.4 MB)
  • 118 Views
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Article
Octaarginine-modified gold nanoparticles enhance the radiosensitivity of human colorectal cancer cell line LS180 to megavoltage radiation
Xuyang Zhang, Hao Wang, Jonathan Andrew Coulter & Ruijie Yang
Pages: 3541-3552
Published online: 19 Jun 2018
AbstractforOctaarginine-modified gold nanoparticles enhance the radiosensitivity of human colorectal cancer cell line LS180 to megavoltage radiation | Full Text | References | PDF (2.6 MB)
  • 73 Views
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Article
X-ray radiation-induced and targeted photodynamic therapy with folic acid-conjugated biodegradable nanoconstructs
Sandhya Clement, Wenjie Chen, Wei Deng & Ewa M Goldys
Pages: 3553-3570
Published online: 28 Feb 2023
AbstractforX-ray radiation-induced and targeted photodynamic therapy with folic acid-conjugated biodegradable nanoconstructs | Full Text | References | PDF (4.2 MB)
  • 128 Views
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Article
Green synthesis of gold and silver nanoparticles from Cannabis sativa (industrial hemp) and their capacity for biofilm inhibition
Priyanka Singh, Santosh Pandit, Jørgen Garnæs, Sanja Tunjic, Venkata RSS Mokkapati, Abida Sultan, Anders Thygesen, Aiga Mackevica, Ramona Valentina Mateiu, Anders Egede Daugaard, Anders Baun & Ivan Mijakovic
Pages: 3571-3591
Published online: 21 Jun 2018
AbstractforGreen synthesis of gold and silver nanoparticles from Cannabis sativa (industrial hemp) and their capacity for biofilm inhibition | Full Text | References | PDF (5.9 MB)
  • 975 Views
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Article
Silica nanoparticle exposure during the neonatal period impairs hippocampal precursor proliferation and social behavior later in life
Jingjing Fu, Junwei Gao, Linji Gong, Yuanyuan Ma, Haiwei Xu, Zhanjun Gu, Jingci Zhu & Xiaotang Fan
Pages: 3593-3608
Published online: 22 Jun 2018
AbstractforSilica nanoparticle exposure during the neonatal period impairs hippocampal precursor proliferation and social behavior later in life | Full Text | References | PDF (15.7 MB)
  • 73 Views
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Article
Enhance the biocompatibility and osseointegration of polyethylene terephthalate ligament by plasma spraying with hydroxyapatite in vitro and in vivo
Siheng Wang, Yunshen Ge, Chengchong Ai, Jia Jiang, Jiangyu Cai, Dandan Sheng, Fang Wan, Xingwang Liu, Yuefeng Hao, Jun Chen & Shiyi Chen
Pages: 3609-3623
Published online: 25 Jun 2018
AbstractforEnhance the biocompatibility and osseointegration of polyethylene terephthalate ligament by plasma spraying with hydroxyapatite in vitro and in vivo | Full Text | References | PDF (17.5 MB)
  • 95 Views
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Article
Lumbrokinase/paclitaxel nanoparticle complex: potential therapeutic applications in bladder cancer
Bo Hu, Ying Yan, Fei Tong, Long Xu, Jia Zhu, Guangtao Xu & Ruilin Shen
Pages: 3625-3640
Published online: 26 Jun 2018
AbstractforLumbrokinase/paclitaxel nanoparticle complex: potential therapeutic applications in bladder cancer | Full Text | References | PDF (2.7 MB)
  • 129 Views
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Corrigendum

Correction
Development and blood compatibility assessment of electrospun polyvinyl alcohol blended with metallocene polyethylene and plectranthus amboinicus (PVA/mPE/PA) for bone tissue engineering [Corrigendum]
Page: 3641
Published online: 25 Jun 2018
CitationforDevelopment and blood compatibility assessment of electrospun polyvinyl alcohol blended with metallocene polyethylene and plectranthus amboinicus (PVA/mPE/PA) for bone tissue engineering [Corrigendum] | Full Text | PDF (141.2 KB)
  • 37 Views
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Original Research

Article
Evaluation of highly carbonated hydroxyapatite bioceramic implant coatings with hierarchical micro-/nanorod topography optimized for osseointegration
Shuang Li, Weijun Yu, Weiqi Zhang, Guohua Zhang, Li Yu & Eryi Lu
Pages: 3643-3659
Published online: 26 Jun 2018
AbstractforEvaluation of highly carbonated hydroxyapatite bioceramic implant coatings with hierarchical micro-/nanorod topography optimized for osseointegration | Full Text | References | PDF (8.1 MB)
  • 102 Views
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Article
Fabrication of multifunctional triple-responsive platform based on CuS-capped periodic mesoporous organosilica nanoparticles for chemo-photothermal therapy
Xiangyang Cheng, Dejian Li, Aiqi Lin, Jun Xu, Liang Wu, Huijie Gu, Zhongyue Huang, Jiangyi Liu, Yiming Zhang & Xiaofan Yin
Pages: 3661-3677
Published online: 26 Jun 2018
AbstractforFabrication of multifunctional triple-responsive platform based on CuS-capped periodic mesoporous organosilica nanoparticles for chemo-photothermal therapy | Full Text | References | PDF (9.3 MB)
  • 81 Views
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Article
Self-assembled biodegradable polymeric micelles to improve dapoxetine delivery across the blood–brain barrier
Mohammed AS Abourehab, Osama AA Ahmed, Gehan F Balata & Waleed H Almalki
Pages: 3679-3687
Published online: 26 Jun 2018
AbstractforSelf-assembled biodegradable polymeric micelles to improve dapoxetine delivery across the blood–brain barrier | Full Text | References | PDF (1.1 MB)
  • 143 Views
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Article
Development of a thermostable nanoemulsion adjuvanted vaccine against tuberculosis using a design-of-experiments approach
Ryan M Kramer, Michelle C Archer, Mark T Orr, Natasha Dubois Cauwelaert, Elyse A Beebe, Po-wei D Huang, Quinton M Dowling, Alicia M Schwartz, Dawn M Fedor, Thomas S Vedvick & Christopher B Fox
Pages: 3689-3711
Published online: 26 Jun 2018
AbstractforDevelopment of a thermostable nanoemulsion adjuvanted vaccine against tuberculosis using a design-of-experiments approach | Full Text | References | PDF (5.2 MB)
  • 188 Views
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Article
Doxorubicin and anti-VEGF siRNA co-delivery via nano-graphene oxide for enhanced cancer therapy in vitro and in vivo
Qi Sun, Xiaoli Wang, Chunying Cui, Jing Li & Yifan Wang
Pages: 3713-3728
Published online: 27 Jun 2018
AbstractforDoxorubicin and anti-VEGF siRNA co-delivery via nano-graphene oxide for enhanced cancer therapy in vitro and in vivo | Full Text | References | PDF (3.6 MB)
  • 109 Views
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Corrigendum

Correction
Biophysical and biological contributions of polyamine-coated carbon nanotubes and bidimensional buckypapers in the delivery of miRNAs to human cells [Corrigendum]
Page: 3729
Published online: 27 Jun 2018
CitationforBiophysical and biological contributions of polyamine-coated carbon nanotubes and bidimensional buckypapers in the delivery of miRNAs to human cells [Corrigendum] | Full Text | PDF (141 KB)
  • 39 Views
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Original Research

Article
Direct modulation of myelin-autoreactive CD4+ and CD8+ T cells in EAE mice by a tolerogenic nanoparticle co-carrying myelin peptide-loaded major histocompatibility complexes, CD47 and multiple regulatory molecules
Weiya Pei, Xin Wan, Khawar Ali Shahzad, Lei Zhang, Shilong Song, Xiaoxiao Jin, Limin Wang, Chen Zhao & Chuanlai Shen
Pages: 3731-3750
Published online: 27 Jun 2018
AbstractforDirect modulation of myelin-autoreactive CD4+ and CD8+ T cells in EAE mice by a tolerogenic nanoparticle co-carrying myelin peptide-loaded major histocompatibility complexes, CD47 and multiple regulatory molecules | Full Text | References | PDF (4.6 MB)
  • 118 Views
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Article
Safety and efficacy of PLGA(Ag-Fe3O4)-coated dental implants in inhibiting bacteria adherence and osteogenic inducement under a magnetic field
Yaping Yang, Shuangshuang Ren, Xuan Zhang, Yijun Yu, Chao Liu, Jie Yang & Leiying Miao
Pages: 3751-3762
Published online: 28 Jun 2018
AbstractforSafety and efficacy of PLGA(Ag-Fe3O4)-coated dental implants in inhibiting bacteria adherence and osteogenic inducement under a magnetic field | Full Text | References | PDF (18.3 MB)
  • 142 Views
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Article
Novel nanocrystal-based solid dispersion with high drug loading, enhanced dissolution, and bioavailability of andrographolide
Yueqin Ma, Yang Yang, Jin Xie, Junnan Xu, Pengfei Yue & Ming Yang
Pages: 3763-3779
Published online: 28 Feb 2023
AbstractforNovel nanocrystal-based solid dispersion with high drug loading, enhanced dissolution, and bioavailability of andrographolide | Full Text | References | PDF (2.8 MB)
  • 236 Views
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Article
Dual-functional Brij-S20-modified nanocrystal formulation enhances the intestinal transport and oral bioavailability of berberine
Wei Xiong, Wei Sang, Ke Gang Linghu, Zhang Feng Zhong, Wai San Cheang, Juan Li, Yuan Jia Hu, Hua Yu & Yi Tao Wang
Pages: 3781-3793
Published online: 28 Feb 2023
AbstractforDual-functional Brij-S20-modified nanocrystal formulation enhances the intestinal transport and oral bioavailability of berberine | Full Text | References | PDF (7.5 MB)
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Article
The prognostic value of quantitative analysis of CCL5 and collagen IV in luminal B (HER2−) subtype breast cancer by quantum-dot-based molecular imaging
Yong-yun Zhu, Chuang Chen, Juan-Juan Li & Sheng-Rong Sun
Pages: 3795-3803
Published online: 28 Jun 2018
AbstractforThe prognostic value of quantitative analysis of CCL5 and collagen IV in luminal B (HER2−) subtype breast cancer by quantum-dot-based molecular imaging | Full Text | References | PDF (3.5 MB)
  • 60 Views
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Article
A novel role in skeletal segment regeneration of extracellular vesicles released from periodontal-ligament stem cells
Francesca Diomede, Marco D’Aurora, Agnese Gugliandolo, Ilaria Merciaro, Valeria Ettorre, Alessia Bramanti, Adriano Piattelli, Valentina Gatta, Emanuela Mazzon, Antonella Fontana & Oriana Trubiani
Pages: 3805-3825
Published online: 29 Jun 2018
AbstractforA novel role in skeletal segment regeneration of extracellular vesicles released from periodontal-ligament stem cells | Full Text | References | PDF (8.1 MB)
  • 139 Views
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Article
Preparation of ginsenoside compound-K mixed micelles with improved retention and antitumor efficacy
Xin Jin, Qing Yang & Ning Cai
Pages: 3827-3838
Published online: 03 Jul 2018
AbstractforPreparation of ginsenoside compound-K mixed micelles with improved retention and antitumor efficacy | Full Text | References | PDF (3.5 MB)
  • 67 Views
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Article
Improved sensitivity of cellular MRI using phase-cycled balanced SSFP of ferumoxytol nanocomplex-labeled macrophages at ultrahigh field
Yelong Shen, Lirong Yan, Xingfeng Shao, Bin Zhao, Jinlun Bai, Wange Lu & Danny JJ Wang
Pages: 3839-3852
Published online: 28 Feb 2023
AbstractforImproved sensitivity of cellular MRI using phase-cycled balanced SSFP of ferumoxytol nanocomplex-labeled macrophages at ultrahigh field | Full Text | References | PDF (4 MB)
  • 45 Views
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Article
Codelivery of doxorubicin and JIP1 siRNA with novel EphA2-targeted PEGylated cationic nanoliposomes to overcome osteosarcoma multidrug resistance
Fateme Haghiralsadat, Ghasem Amoabediny, Samira Naderinezhad, Behrouz Zandieh-Doulabi, Tymour Forouzanfar & Marco N Helder
Pages: 3853-3866
Published online: 03 Jul 2018
AbstractforCodelivery of doxorubicin and JIP1 siRNA with novel EphA2-targeted PEGylated cationic nanoliposomes to overcome osteosarcoma multidrug resistance | Full Text | References | PDF (4.2 MB)
  • 114 Views
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Article
Nanoscaled and microscaled parallel topography promotes tenogenic differentiation of ASC and neotendon formation in vitro
Kaili Zhou, Bei Feng, Wenbo Wang, Yongkang Jiang, Wenjie Zhang, Guangdong Zhou, Ting Jiang, Yilin Cao & Wei Liu
Pages: 3867-3881
Published online: 04 Jul 2018
AbstractforNanoscaled and microscaled parallel topography promotes tenogenic differentiation of ASC and neotendon formation in vitro | Full Text | References | PDF (4.4 MB)
  • 90 Views
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Article
Nanoporous diopside modulates biocompatibility, degradability and osteogenesis of bioactive scaffolds of gliadin-based composites for new bone formation
Zhaoyu Ba, Zhaoxiong Chen, Yufeng Huang, Du Feng, Qinghui Zhao, Jianguang Zhu & Desheng Wu
Pages: 3883-3896
Published online: 04 Jul 2018
AbstractforNanoporous diopside modulates biocompatibility, degradability and osteogenesis of bioactive scaffolds of gliadin-based composites for new bone formation | Full Text | References | PDF (6.5 MB)
  • 82 Views
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Article
Stimulation of wound healing using bioinspired hydrogels with basic fibroblast growth factor (bFGF)
Xiaoyu Zhang, Xiaoning Kang, Lijun Jin, Jie Bai, Wei Liu & Zunyi Wang
Pages: 3897-3906
Published online: 04 Jul 2018
AbstractforStimulation of wound healing using bioinspired hydrogels with basic fibroblast growth factor (bFGF) | Full Text | References | PDF (3.5 MB)
  • 303 Views
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Article
RETRACTED ARTICLE: Phase-shift, targeted nanoparticles for ultrasound molecular imaging by low intensity focused ultrasound irradiation
Maoping Li, Hua Luo, Weiyang Zhang, Kunyan He, Yong Chen, Jianxin Liu, Junchen Chen, Dong Wang, Lan Hao, Haitao Ran, Yuanyi Zheng, Zhigang Wang & Pan Li
Pages: 3907-3920
Published online: 04 Jul 2018
AbstractforRETRACTED ARTICLE: Phase-shift, targeted nanoparticles for ultrasound molecular imaging by low intensity focused ultrasound irradiation | PDF (5.2 MB)
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Review

Review Article
Application of active targeting nanoparticle delivery system for chemotherapeutic drugs and traditional/herbal medicines in cancer therapy: a systematic review
Nadda Muhamad, Tullayakorn Plengsuriyakarn & Kesara Na-Bangchang
Pages: 3921-3935
Published online: 04 Jul 2018
AbstractforApplication of active targeting nanoparticle delivery system for chemotherapeutic drugs and traditional/herbal medicines in cancer therapy: a systematic review | Full Text | References | PDF (709 KB)
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Original Research

Article
Intravenously-injected gold nanoparticles (AuNPs) access intracerebral F98 rat gliomas better than AuNPs infused directly into the tumor site by convection enhanced delivery
Henry M Smilowitz, Alexandria Meyers, Khalil Rahman, Nathaniel A Dyment, Dan Sasso, Crystal Xue, Douglas L Oliver, Alexander Lichtler, Xiaomeng Deng, Sharif M Ridwan, Lauren J Tarmu, Qian Wu, Andrew L Salner, Ketan R Bulsara, Daniel N Slatkin & James F Hainfeld
Pages: 3937-3948
Published online: 28 Feb 2023
AbstractforIntravenously-injected gold nanoparticles (AuNPs) access intracerebral F98 rat gliomas better than AuNPs infused directly into the tumor site by convection enhanced delivery | Full Text | References | PDF (5.4 MB)
  • 83 Views
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Article
Nanostructured Ti surfaces and retinoic acid/dexamethasone present a spatial framework for the maturation and amelogenesis of LS-8 cells
Nan Jiang, Lu Chen, Qianli Ma & Jianping Ruan
Pages: 3949-3964
Published online: 09 Jul 2018
AbstractforNanostructured Ti surfaces and retinoic acid/dexamethasone present a spatial framework for the maturation and amelogenesis of LS-8 cells | Full Text | References | PDF (5.6 MB)
  • 49 Views
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Article
Modified magnetic nanoparticles by PEG-400-immobilized Ag nanoparticles (Fe3O4@PEG–Ag) as a core/shell nanocomposite and evaluation of its antimicrobial activity
Kamiar Zomorodian, Hamed Veisi, Seyed Mahmoud Mousavi, Mahmoud Sadeghi Ataabadi, Somayeh Yazdanpanah, Jafar Bagheri, Ali Parvizi Mehr, Saba Hemmati & Hojat Veisi
Pages: 3965-3973
Published online: 09 Jul 2018
AbstractforModified magnetic nanoparticles by PEG-400-immobilized Ag nanoparticles (Fe3O4@PEG–Ag) as a core/shell nanocomposite and evaluation of its antimicrobial activity | Full Text | References | PDF (1.6 MB)
  • 237 Views
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Article
Montmorillonite/chitosan nanoparticles as a novel controlled-release topical ophthalmic delivery system for the treatment of glaucoma
Juan Li, Shuangyan Tian, Qi Tao, Yawen Zhao, Ruyi Gui, Fan Yang, Lingquan Zang, Yanzhong Chen, Qineng Ping & Dongzhi Hou
Pages: 3975-3987
Published online: 28 Feb 2023
AbstractforMontmorillonite/chitosan nanoparticles as a novel controlled-release topical ophthalmic delivery system for the treatment of glaucoma | Full Text | References | PDF (2.8 MB)
  • 190 Views
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Article
Polysaccharide-modified nanoparticles with intelligent CD44 receptor targeting ability for gene delivery
Wen Jen Lin & Wei Chi Lee
Pages: 3989-4002
Published online: 10 Jul 2018
AbstractforPolysaccharide-modified nanoparticles with intelligent CD44 receptor targeting ability for gene delivery | Full Text | References | PDF (5.1 MB)
  • 153 Views
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Article
Non-ionic thiolated cyclodextrins – the next generation
Ali Moghadam, Muhammad Ijaz, Mulazim Hussain Asim, Arshad Mahmood, Max Jelkmann, Barbara Matuszczak & Andreas Bernkop-Schnürch
Pages: 4003-4013
Published online: 10 Jul 2018
AbstractforNon-ionic thiolated cyclodextrins – the next generation | Full Text | References | PDF (1.7 MB)
  • 133 Views
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Article
Lyophilization and stability of antibody-conjugated mesoporous silica nanoparticle with cationic polymer and PEG for siRNA delivery
Worapol Ngamcherdtrakul, Thanapon Sangvanich, Moataz Reda, Shenda Gu, Daniel Bejan & Wassana Yantasee
Pages: 4015-4027
Published online: 10 Jul 2018
AbstractforLyophilization and stability of antibody-conjugated mesoporous silica nanoparticle with cationic polymer and PEG for siRNA delivery | Full Text | References | PDF (2.5 MB)
  • 247 Views
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Article
Nanostructured titanium regulates osseointegration via influencing macrophage polarization in the osteogenic environment
Jinjin Wang, Fanhui Meng, Wen Song, Jingyi Jin, Qianli Ma, Dongdong Fei, Liang Fang, Lihua Chen, Qintao Wang & Yumei Zhang
Pages: 4029-4043
Published online: 10 Jul 2018
AbstractforNanostructured titanium regulates osseointegration via influencing macrophage polarization in the osteogenic environment | Full Text | References | PDF (3.3 MB)
  • 129 Views
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Article
Triphenylphosphonium and D-α-tocopheryl polyethylene glycol 1000 succinate-modified, tanshinone IIA-loaded lipid-polymeric nanocarriers for the targeted therapy of myocardial infarction
Shouwen Zhang, Jingfang Li, Shunpeng Hu, Fangfang Wu & Xianzhao Zhang
Pages: 4045-4057
Published online: 10 Jul 2018
AbstractforTriphenylphosphonium and D-α-tocopheryl polyethylene glycol 1000 succinate-modified, tanshinone IIA-loaded lipid-polymeric nanocarriers for the targeted therapy of myocardial infarction | Full Text | References | PDF (3.1 MB)
  • 115 Views
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Article
Modulation of the intrinsic neuronal excitability by multifunctional liposomes tailored for the treatment of Alzheimer’s disease
Anna Binda, Alice Panariti, Andrea Barbuti, Carmen Murano, Roberta Dal Magro, Massimo Masserini, Francesca Re & Ilaria Rivolta
Pages: 4059-4071
Published online: 11 Jul 2018
AbstractforModulation of the intrinsic neuronal excitability by multifunctional liposomes tailored for the treatment of Alzheimer’s disease | Full Text | References | PDF (2.5 MB)
  • 118 Views
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Article
Uptake and transport of pullulan acetate nanoparticles in the BeWo b30 placental barrier cell model
Hongbo Tang, Ziwen Jiang, Haibo He, Xiaoqin Li, Haipeng Hu, Ning Zhang, Yinmei Dai & Zhimin Zhou
Pages: 4073-4082
Published online: 11 Jul 2018
AbstractforUptake and transport of pullulan acetate nanoparticles in the BeWo b30 placental barrier cell model | Full Text | References | PDF (5.9 MB)
  • 137 Views
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Article
Loading BMP-2 on nanostructured hydroxyapatite microspheres for rapid bone regeneration
Panyu Zhou, Jianghong Wu, Yan Xia, Ye Yuan, Hongyue Zhang, Shuogui Xu & Kaili Lin
Pages: 4083-4092
Published online: 11 Jul 2018
AbstractforLoading BMP-2 on nanostructured hydroxyapatite microspheres for rapid bone regeneration | Full Text | References | PDF (3 MB)
  • 92 Views
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Article
In situ fabrication of radiopaque microcapsules for oral delivery and real-time gastrointestinal tracking of Bifidobacterium
Zhengzou Fang, Rong Jiang, Lirong Zhang, Yunchao Wu, Xuefen Zhao, Lulu Zhao, Jiangang Li, Shengqiang Zou, Miaomiao Zhang & Fengyi Du
Pages: 4093-4105
Published online: 12 Jul 2018
AbstractforIn situ fabrication of radiopaque microcapsules for oral delivery and real-time gastrointestinal tracking of Bifidobacterium | Full Text | References | PDF (2.8 MB)
  • 62 Views
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Article
Nanostructured lipid carriers co-delivering lapachone and doxorubicin for overcoming multidrug resistance in breast cancer therapy
Xin Li, Xiaoqian Jia & Hu Niu
Pages: 4107-4119
Published online: 28 Feb 2023
AbstractforNanostructured lipid carriers co-delivering lapachone and doxorubicin for overcoming multidrug resistance in breast cancer therapy | Full Text | References | PDF (6.4 MB)
  • 158 Views
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Article
Dextran-based biodegradable nanoparticles: an alternative and convenient strategy for treatment of traumatic spinal cord injury
Wei Liu, Peng Quan, Qingqing Li, Pengyu Tang, Jian Chen, Tao Jiang & Weihua Cai
Pages: 4121-4132
Published online: 13 Jul 2018
AbstractforDextran-based biodegradable nanoparticles: an alternative and convenient strategy for treatment of traumatic spinal cord injury | Full Text | References | PDF (7.8 MB)
  • 910 Views
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Article
Galactosylated PLGA nanoparticles for the oral delivery of resveratrol: enhanced bioavailability and in vitro anti-inflammatory activity
Frederick YK Siu, Shaotang Ye, Hui Lin & Shoujun Li
Pages: 4133-4144
Published online: 13 Jul 2018
AbstractforGalactosylated PLGA nanoparticles for the oral delivery of resveratrol: enhanced bioavailability and in vitro anti-inflammatory activity | Full Text | References | PDF (4.4 MB)
  • 209 Views
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Article
Thermally induced self-agglomeration 3D scaffolds with BMP-2-loaded core–shell fibers for enhanced osteogenic differentiation of rat adipose-derived stem cells
Shuying Hu, Hanbang Chen, Xuefeng Zhou, Gang Chen, Ke Hu, Yi Cheng, Lili Wang & Feimin Zhang
Pages: 4145-4155
Published online: 17 Jul 2018
AbstractforThermally induced self-agglomeration 3D scaffolds with BMP-2-loaded core–shell fibers for enhanced osteogenic differentiation of rat adipose-derived stem cells | Full Text | References | PDF (6.4 MB)
  • 54 Views
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Article
Preparation of chitin-amphipathic anion/quaternary ammonium salt ecofriendly dressing and its effect on wound healing in mice
Daijun Zhou, Ruijia Yang, Tao Yang, Malcolm Xing & Gaoxing Luo
Pages: 4157-4169
Published online: 17 Jul 2018
AbstractforPreparation of chitin-amphipathic anion/quaternary ammonium salt ecofriendly dressing and its effect on wound healing in mice | Full Text | References | PDF (6.3 MB)
  • 94 Views
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Article
Study of the mechanism of environmentally friendly translucent balsa-modified lysozyme dressing for facilitating wound healing
Daijun Zhou, Tao Yang, Wei Qian, Malcolm Xing & Gaoxing Luo
Pages: 4171-4187
Published online: 17 Jul 2018
AbstractforStudy of the mechanism of environmentally friendly translucent balsa-modified lysozyme dressing for facilitating wound healing | Full Text | References | PDF (6.1 MB)
  • 63 Views
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Article
Chitosan-based nanoformulated (−)-epigallocatechin-3-gallate (EGCG) modulates human keratinocyte-induced responses and alleviates imiquimod-induced murine psoriasiform dermatitis
Jean Christopher Chamcheu, Imtiaz A Siddiqui, Vaqar M Adhami, Stephane Esnault, Dhruba J Bharali, Abiola S Babatunde, Stephanie Adame, Randall J Massey, Gary S Wood, B Jack Longley, Shaker A Mousa & Hasan Mukhtar
Pages: 4189-4206
Published online: 20 Jul 2018
AbstractforChitosan-based nanoformulated (−)-epigallocatechin-3-gallate (EGCG) modulates human keratinocyte-induced responses and alleviates imiquimod-induced murine psoriasiform dermatitis | Full Text | References | PDF (6.3 MB)
  • 185 Views
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Corrigendum

Correction
Synthesis of biocompatible iron oxide nanoparticles as a drug delivery vehicle [Corrigendum]
Pages: 4207-4208
Published online: 19 Jul 2018
CitationforSynthesis of biocompatible iron oxide nanoparticles as a drug delivery vehicle [Corrigendum] | Full Text | PDF (565.2 KB)
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Original Research

Article
Mitochondria-targeted delivery of doxorubicin to enhance antitumor activity with HER-2 peptide-mediated multifunctional pH-sensitive DQAsomes
Menghao Shi, Jiulong Zhang, Xiaowei Li, Shuang Pan, Jie Li, Chunrong Yang, Haiyang Hu, Mingxi Qiao, Dawei Chen & Xiuli Zhao
Pages: 4209-4226
Published online: 18 Jul 2018
AbstractforMitochondria-targeted delivery of doxorubicin to enhance antitumor activity with HER-2 peptide-mediated multifunctional pH-sensitive DQAsomes | Full Text | References | PDF (10 MB)
  • 96 Views
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Review

Review Article
Solution-enhanced dispersion by supercritical fluids: an ecofriendly nanonization approach for processing biomaterials and pharmaceutical compounds
Ranjith Kumar Kankala, Biao-Qi Chen, Chen-Guang Liu, Han-Xiao Tang, Shi-Bin Wang & Ai-Zheng Chen
Pages: 4227-4245
Published online: 23 Jul 2018
AbstractforSolution-enhanced dispersion by supercritical fluids: an ecofriendly nanonization approach for processing biomaterials and pharmaceutical compounds | Full Text | References | PDF (3.1 MB)
  • 127 Views
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Original Research

Article
Bioengineering the spider silk sequence to modify its affinity for drugs
Kamil Kucharczyk, Marek Weiss, Katarzyna Jastrzebska, Magdalena Luczak, Arkadiusz Ptak, Maciej Kozak, Andrzej Mackiewicz & Hanna Dams-Kozlowska
Pages: 4247-4261
Published online: 20 Jul 2018
AbstractforBioengineering the spider silk sequence to modify its affinity for drugs | Full Text | References | PDF (4.2 MB)
  • 80 Views
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Review

Review Article
Magnetic polymeric nanoassemblies for magnetic resonance imaging-combined cancer theranostics
Shenglong Gan, Yisheng Lin, Yancong Feng, Lingling Shui, Hao Li & Guofu Zhou
Pages: 4263-4281
Published online: 23 Jul 2018
AbstractforMagnetic polymeric nanoassemblies for magnetic resonance imaging-combined cancer theranostics | Full Text | References | PDF (4.2 MB)
  • 71 Views
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Original Research

Article
Three-photon imaging using defect-induced photoluminescence in biocompatible ZnO nanoparticles
Achyut J Raghavendra, Wren E Gregory, Tyler J Slonecki, Yongchang Dong, Indushekhar Persaud, Jared M Brown, Terri F Bruce & Ramakrishna Podila
Pages: 4283-4290
Published online: 23 Jul 2018
AbstractforThree-photon imaging using defect-induced photoluminescence in biocompatible ZnO nanoparticles | Full Text | References | PDF (1.5 MB)
  • 73 Views
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Article
Tailor-made PEG-DA-CuS nanoparticles enriched in tumor with the aid of retro Diels–Alder reaction triggered by their intrinsic photothermal property
Jie Sheng, Beibei Ma, Qian Yang, Chao Zhang, Zhongying Jiang & Entomack Borrathybay
Pages: 4291-4302
Published online: 23 Jul 2018
AbstractforTailor-made PEG-DA-CuS nanoparticles enriched in tumor with the aid of retro Diels–Alder reaction triggered by their intrinsic photothermal property | Full Text | References | PDF (7 MB)
  • 52 Views
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Article
Antimycobacterial susceptibility evaluation of rifampicin and isoniazid benz-hydrazone in biodegradable polymeric nanoparticles against Mycobacterium tuberculosis H37Rv strain
Sushruta S Hakkimane, Vishnu Prasad Shenoy, Santosh L Gaonkar, Indira Bairy & Bharath Raja Guru
Pages: 4303-4318
Published online: 23 Jul 2018
AbstractforAntimycobacterial susceptibility evaluation of rifampicin and isoniazid benz-hydrazone in biodegradable polymeric nanoparticles against Mycobacterium tuberculosis H37Rv strain | Full Text | References | PDF (3.9 MB)
  • 235 Views
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Article
Facile fabrication of hypericin-entrapped glyconanoparticles for targeted photodynamic therapy
Chen Shao, Kun Shang, Huaibao Xu, Yu Zhang, Zhichao Pei & Yuxin Pei
Pages: 4319-4331
Published online: 23 Jul 2018
AbstractforFacile fabrication of hypericin-entrapped glyconanoparticles for targeted photodynamic therapy | Full Text | References | PDF (15.5 MB)
  • 70 Views
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Article
Enhanced endosomal escape by photothermal activation for improved small interfering RNA delivery and antitumor effect
Xi Yang, Bo Fan, Wei Gao, Liping Li, Tingting Li, Jinghua Sun, Xiaoyang Peng, Xiaoyan Li, Zhenjun Wang, Binquan Wang, Ruiping Zhang & Jun Xie
Pages: 4333-4344
Published online: 23 Jul 2018
AbstractforEnhanced endosomal escape by photothermal activation for improved small interfering RNA delivery and antitumor effect | Full Text | References | PDF (9.3 MB)
  • 111 Views
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Article
Optimization of molecularly targeted MRI in the brain: empirical comparison of sequences and particles
Niloufar Zarghami, Alexandre A Khrapitchev, Francisco Perez-Balderas, Manuel Sarmiento Soto, James R Larkin, Luca Bau & Nicola R Sibson
Pages: 4345-4359
Published online: 25 Jul 2018
AbstractforOptimization of molecularly targeted MRI in the brain: empirical comparison of sequences and particles | Full Text | References | PDF (13.3 MB)
  • 63 Views
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Article
Reduction-sensitive CD44 receptor-targeted hyaluronic acid derivative micelles for doxorubicin delivery
Yishun Yang, Yuan Zhao, Jinshuai Lan, Yanan Kang, Tong Zhang, Yue Ding, Xinyu Zhang & Lu Lu
Pages: 4361-4378
Published online: 26 Jul 2018
AbstractforReduction-sensitive CD44 receptor-targeted hyaluronic acid derivative micelles for doxorubicin delivery | Full Text | References | PDF (13.6 MB)
  • 210 Views
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Article
Folic acid-conjugated mesoporous silica nanoparticles for enhanced therapeutic efficacy of topotecan in retina cancers
Wei Qu, Bo Meng, Yangyang Yu & Shaowei Wang
Pages: 4379-4389
Published online: 27 Jul 2018
AbstractforFolic acid-conjugated mesoporous silica nanoparticles for enhanced therapeutic efficacy of topotecan in retina cancers | Full Text | References | PDF (3.9 MB)
  • 171 Views
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Article
Rho GTPases in A549 and Caco-2 cells dominating the endocytic pathways of nanocarbons with different morphologies
Siyang Song, Hongzhe Fu, Bing He, Dan Wang, Mengmeng Qin, Dan Yang, Dechun Liu, Ge Song, Yujie Shi, Hua Zhang, Xueqing Wang, Wenbing Dai & Qiang Zhang
Pages: 4391-4404
Published online: 28 Feb 2023
AbstractforRho GTPases in A549 and Caco-2 cells dominating the endocytic pathways of nanocarbons with different morphologies | Full Text | References | PDF (3.9 MB)
  • 71 Views
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Article
The effect of the carbodiimide cross-linker on the structural and biocompatibility properties of collagen–chondroitin sulfate electrospun mat
Sheyda Akhshabi, Esmaeil Biazar, Vivek Singh, Saeed Heidari Keshel & Nagaraja Geetha
Pages: 4405-4416
Published online: 30 Jul 2018
AbstractforThe effect of the carbodiimide cross-linker on the structural and biocompatibility properties of collagen–chondroitin sulfate electrospun mat | Full Text | References | PDF (5.5 MB)
  • 134 Views
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Article
Iridium (III) complex-loaded liposomes as a drug delivery system for lung cancer through mitochondrial dysfunction
Cancheng Liao, Danqiao Xu, Xiaohong Liu, Yuqi Fang, Jun Yi, Xiaofang Li & Bohong Guo
Pages: 4417-4431
Published online: 30 Jul 2018
AbstractforIridium (III) complex-loaded liposomes as a drug delivery system for lung cancer through mitochondrial dysfunction | Full Text | References | PDF (4.9 MB)
  • 113 Views
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Article
A GPC3-specific aptamer-mediated magnetic resonance probe for hepatocellular carcinoma
Menglong Zhao, Zhuang Liu, Lili Dong, Hongxin Zhou, Shuohui Yang, Weizhong Wu & Jiang Lin
Pages: 4433-4443
Published online: 01 Aug 2018
AbstractforA GPC3-specific aptamer-mediated magnetic resonance probe for hepatocellular carcinoma | Full Text | References | PDF (4.5 MB)
  • 72 Views
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Review

Review Article
Evaluation of immunoresponses and cytotoxicity from skin exposure to metallic nanoparticles
Menglei Wang, Xuan Lai, Longquan Shao & Li Li
Pages: 4445-4459
Published online: 28 Feb 2023
AbstractforEvaluation of immunoresponses and cytotoxicity from skin exposure to metallic nanoparticles | Full Text | References | PDF (9.8 MB)
  • 250 Views
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Original Research

Article
Synthesis of a hemin-containing copolymer as a novel immunostimulator that induces IFN-gamma production
Kazuaki Hoshi, Tomohiko Yamazaki, Chiaki Yoshikawa, Wakako Tsugawa, Kazunori Ikebukuro & Koji Sode
Pages: 4461-4472
Published online: 28 Feb 2023
AbstractforSynthesis of a hemin-containing copolymer as a novel immunostimulator that induces IFN-gamma production | Full Text | References | PDF (3 MB)
  • 58 Views
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Article
Antimicrobial quaternary ammonium organosilane cross-linked nanofibrous collagen scaffolds for tissue engineering
Chetna Dhand, Yamini Balakrishnan, Seow Theng Ong, Neeraj Dwivedi, Jayarama R Venugopal, Sriram Harini, Chak Ming Leung, Kenny Zhi Wei Low, Xian Jun Loh, Roger W Beuerman, Seeram Ramakrishna, Navin Kumar Verma & Rajamani Lakshminarayanan
Pages: 4473-4492
Published online: 03 Aug 2018
AbstractforAntimicrobial quaternary ammonium organosilane cross-linked nanofibrous collagen scaffolds for tissue engineering | Full Text | References | PDF (10.3 MB)
  • 94 Views
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Article
Praziquantel–lipid nanocapsules: an oral nanotherapeutic with potential Schistosoma mansoni tegumental targeting
Rokaya O Amara, Alyaa A Ramadan, Riham M El-Moslemany, Maha M Eissa, Mervat Z El-Azzouni & Labiba K El-Khordagui
Pages: 4493-4505
Published online: 06 Aug 2018
AbstractforPraziquantel–lipid nanocapsules: an oral nanotherapeutic with potential Schistosoma mansoni tegumental targeting | Full Text | References | PDF (5.3 MB)
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Corrigendum

Correction
Engineered exosome-mediated delivery of functionally active miR-26a and its enhanced suppression effect in HepG2 cells [Erratum]
Page: 4507
Published online: 07 Aug 2018
CitationforEngineered exosome-mediated delivery of functionally active miR-26a and its enhanced suppression effect in HepG2 cells [Erratum] | Full Text | PDF (139.9 KB)
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Original Research

Article
Magnetic targeting of paclitaxel-loaded poly(lactic-co-glycolic acid)-based nanoparticles for the treatment of glioblastoma
Lakshmi Pallavi Ganipineni, Bernard Ucakar, Nicolas Joudiou, John Bianco, Pierre Danhier, Mengnan Zhao, Chiara Bastiancich, Bernard Gallez, Fabienne Danhier & Véronique Préat
Pages: 4509-4521
Published online: 08 Aug 2018
AbstractforMagnetic targeting of paclitaxel-loaded poly(lactic-co-glycolic acid)-based nanoparticles for the treatment of glioblastoma | Full Text | References | PDF (4.3 MB)
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Article
Comparative functional dynamics studies on the enzyme nano-bio interface
Spencer E Thomas, Jeffrey Comer, Min Jung Kim, Shanna Marroquin, Vaibhav Murthy, Meghana Ramani, Tabetha Gaile Hopke, Jayden McCall, Seong-O Choi & Robert K DeLong
Pages: 4523-4536
Published online: 28 Feb 2023
AbstractforComparative functional dynamics studies on the enzyme nano-bio interface | Full Text | References | PDF (3.2 MB)
  • 50 Views
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Article
Application of quasi-emulsification and modified double emulsification techniques for formulation of tacrolimus microsponges
Muhammad Zaman, Sundus Qureshi, Kishwar Sultana, Muhammad Hanif, Asif Mahmood, Zaib Ali Shaheryar, Faisal Gulzar, Kashif Barkat & Mohamed M Abdel-Daim
Pages: 4537-4548
Published online: 10 Aug 2018
AbstractforApplication of quasi-emulsification and modified double emulsification techniques for formulation of tacrolimus microsponges | Full Text | References | PDF (2 MB)
  • 168 Views
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Article
A complex micellar system co-delivering curcumin with doxorubicin against cardiotoxicity and tumor growth
Di Zhang, Qian Xu, Ning Wang, Yanting Yang, Jiaqi Liu, Guohua Yu, Xin Yang, Hui Xu & Hongbo Wang
Pages: 4549-4561
Published online: 10 Aug 2018
AbstractforA complex micellar system co-delivering curcumin with doxorubicin against cardiotoxicity and tumor growth | Full Text | References | PDF (1.6 MB)
  • 120 Views
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Article
Mechanisms of the effectiveness of poly(ε-caprolactone) lipid-core nanocapsules loaded with methotrexate on glioblastoma multiforme treatment
Natalia Rubio Claret Pereira, Rodrigo Azevedo Loiola, Stephen Fernandes Rodrigues, Catiuscia P de Oliveira, Sabrina L Büttenbender, Silvia S Guterres, Adriana R Pohlmann & Sandra H Farsky
Pages: 4563-4573
Published online: 15 Aug 2018
AbstractforMechanisms of the effectiveness of poly(ε-caprolactone) lipid-core nanocapsules loaded with methotrexate on glioblastoma multiforme treatment | Full Text | References | PDF (2.1 MB)
  • 69 Views
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Article
Biophysical, docking, and cellular studies on the effects of cerium oxide nanoparticles on blood components: in vitro
Neda Eskandari, Mohammad Mahdi Nejadi Babadaei, Sanaz Nikpur, Ghazal Ghasrahmad, Farnoosh Attar, Masoumeh Heshmati, Keivan Akhtari, Seyed Mahdi Rezayat Sorkhabadi, Seyyedeh Elaheh Mousavi & Mojtaba Falahati
Pages: 4575-4589
Published online: 10 Aug 2018
AbstractforBiophysical, docking, and cellular studies on the effects of cerium oxide nanoparticles on blood components: in vitro | Full Text | References | PDF (3 MB)
  • 119 Views
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Article
Electrospun silver ion-loaded calcium phosphate/chitosan antibacterial composite fibrous membranes for guided bone regeneration
Shue Jin, Jidong Li, Jian Wang, Jiaxing Jiang, Yi Zuo, Yubao Li & Fang Yang
Pages: 4591-4605
Published online: 10 Aug 2018
AbstractforElectrospun silver ion-loaded calcium phosphate/chitosan antibacterial composite fibrous membranes for guided bone regeneration | Full Text | References | PDF (14.5 MB)
  • 165 Views
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Article
T1–T2 molecular magnetic resonance imaging of renal carcinoma cells based on nano-contrast agents
Jingjing Li, Jia You, Chen Wu, Yue Dai, Meilin Shi, Lina Dong & Kai Xu
Pages: 4607-4625
Published online: 10 Aug 2018
AbstractforT1–T2 molecular magnetic resonance imaging of renal carcinoma cells based on nano-contrast agents | Full Text | References | PDF (6.2 MB)
  • 151 Views
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Article
Cyclic RGD-conjugated Pluronic® blending system for active, targeted drug delivery
Chaemin Lim, Junseong Moon, Taehoon Sim, Ngoc Ha Hoang, Woong Roeck Won, Eun Seong Lee, Yu Seok Youn, Han-Gon Choi, Kyungsoo Oh & Kyung Taek Oh
Pages: 4627-4639
Published online: 10 Aug 2018
AbstractforCyclic RGD-conjugated Pluronic® blending system for active, targeted drug delivery | Full Text | References | PDF (8.5 MB)
  • 107 Views
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Article
Matrix metalloproteinase 2/9-triggered-release micelles for inhaled drug delivery to treat lung cancer: preparation and in vitro/in vivo studies
Xiaofei Wang, Qinyue Chen, Xiaoyan Zhang, Xiaoqing Ren, Xiulei Zhang, Lin Meng, Huihui Liang, Xianyi Sha & Xiaoling Fang
Pages: 4641-4659
Published online: 28 Feb 2023
AbstractforMatrix metalloproteinase 2/9-triggered-release micelles for inhaled drug delivery to treat lung cancer: preparation and in vitro/in vivo studies | Full Text | References | PDF (2.9 MB)
  • 84 Views
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Article
Breath volatolomics for diagnosing chronic rhinosinusitis
Yoav Y Broza, Itzhak Braverman & Hossam Haick
Pages: 4661-4670
Published online: 14 Aug 2018
AbstractforBreath volatolomics for diagnosing chronic rhinosinusitis | Full Text | References | PDF (1.2 MB)
  • 75 Views
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Article
Technetium-99m chelator-free radiolabeling of specific glutamine tumor imaging nanoprobe: in vitro and in vivo evaluations
Seyedeh Masoumeh Ghoreishi, Ali Khalaj, Omid Sabzevari, Leila Badrzadeh, Pardis Mohammadzadeh, Seyed Shahaboddin Mousavi Motlagh, Ahmad Bitarafan-Rajabi & Mehdi Shafiee Ardestani
Pages: 4671-4683
Published online: 15 Aug 2018
AbstractforTechnetium-99m chelator-free radiolabeling of specific glutamine tumor imaging nanoprobe: in vitro and in vivo evaluations | Full Text | References | PDF (4.7 MB)
  • 126 Views
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Article
Overcoming multidrug resistance through inhalable siRNA nanoparticles-decorated porous microparticles based on supercritical fluid technology
Pei-Yao Xu, Ranjith Kumar Kankala, Yu-Jing Pan, Hui Yuan, Shi-Bin Wang & Ai-Zheng Chen
Pages: 4685-4698
Published online: 15 Aug 2018
AbstractforOvercoming multidrug resistance through inhalable siRNA nanoparticles-decorated porous microparticles based on supercritical fluid technology | Full Text | References | PDF (2.4 MB)
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Expert Opinion

Editorial
Enhancing anticancer effects, decreasing risks and solving practical problems facing 3-bromopyruvate in clinical oncology: 10 years of research experience
Salah Mohamed El Sayed
Pages: 4699-4709
Published online: 15 Aug 2018
AbstractforEnhancing anticancer effects, decreasing risks and solving practical problems facing 3-bromopyruvate in clinical oncology: 10 years of research experience | Full Text | References | PDF (1.1 MB)
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Original Research

Article
A novel albumin wrapped nanosuspension of meloxicam to improve inflammation-targeting effects
Qi Li, Fen Chen, Yun Liu, Shihui Yu, Xiumei Gai, Mingzhu Ye, Xinggang Yang & Weisan Pan
Pages: 4711-4725
Published online: 15 Aug 2018
AbstractforA novel albumin wrapped nanosuspension of meloxicam to improve inflammation-targeting effects | Full Text | References | PDF (5 MB)
  • 97 Views
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Review

Review Article
Recent advances in “smart” delivery systems for extended drug release in cancer therapy
Regina-Veronicka Kalaydina, Komal Bajwa, Bessi Qorri, Alexandria Decarlo & Myron R Szewczuk
Pages: 4727-4745
Published online: 20 Aug 2018
AbstractforRecent advances in “smart” delivery systems for extended drug release in cancer therapy | Full Text | References | PDF (1.5 MB)
  • 607 Views
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Original Research

Article
Evaluation of the antibacterial activity of tilmicosin-SLN against Streptococcus agalactiae: in vitro and in vivo studies
Luyan Zhu, Xiaoxia Cao, Qinxin Xu, Jing Su, Xihe Li & Wenzhong Zhou
Pages: 4747-4755
Published online: 17 Aug 2018
AbstractforEvaluation of the antibacterial activity of tilmicosin-SLN against Streptococcus agalactiae: in vitro and in vivo studies | Full Text | References | PDF (880.8 KB)
  • 68 Views
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Article
In vivo toxicological evaluation of graphene oxide nanoplatelets for clinical application
Mohammad Amrollahi-Sharifabadi, Mohammad Kazem Koohi, Ehsan Zayerzadeh, Mohammad Hassan Hablolvarid, Jalal Hassan & Alexander M Seifalian
Pages: 4757-4769
Published online: 22 Aug 2018
AbstractforIn vivo toxicological evaluation of graphene oxide nanoplatelets for clinical application | Full Text | References | PDF (2.2 MB)
  • 170 Views
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Article
Magnetic nanoparticle hyperthermia potentiates paclitaxel activity in sensitive and resistant breast cancer cells
Angelie Rivera-Rodriguez, Andreina Chiu-Lam, Viacheslav M Morozov, Alexander M Ishov & Carlos Rinaldi
Pages: 4771-4779
Published online: 23 Aug 2018
AbstractforMagnetic nanoparticle hyperthermia potentiates paclitaxel activity in sensitive and resistant breast cancer cells | Full Text | References | PDF (2.1 MB)
  • 98 Views
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Article
Delivery siRNA with a novel gene vector for glioma therapy by targeting Gli1
Peizhi Zhou, Yue Cao, Xiaoxiao Liu, Ting Yu, Qian Xu, Chao You, Xiang Gao & Yuquan Wei
Pages: 4781-4793
Published online: 27 Aug 2018
AbstractforDelivery siRNA with a novel gene vector for glioma therapy by targeting Gli1 | Full Text | References | PDF (5.2 MB)
  • 57 Views
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Article
Diagnosis of rubella virus using antigen-conjugated Au@Pt nanorods as nanozyme probe
Tao Zhang, Fang Tian, Lin Long, Jianbo Liu & Xiaochun Wu
Pages: 4795-4805
Published online: 23 Aug 2018
AbstractforDiagnosis of rubella virus using antigen-conjugated Au@Pt nanorods as nanozyme probe | Full Text | References | PDF (4.6 MB)
  • 124 Views
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Article
Fabrication of ultra-small monolayer graphene quantum dots by pyrolysis of trisodium citrate for fluorescent cell imaging
Guo-Lin Hong, Hai-Ling Zhao, Hao-Hua Deng, Hui-Jing Yang, Hua-Ping Peng, Yin-Huan Liu & Wei Chen
Pages: 4807-4815
Published online: 24 Aug 2018
AbstractforFabrication of ultra-small monolayer graphene quantum dots by pyrolysis of trisodium citrate for fluorescent cell imaging | Full Text | References | PDF (4.1 MB)
  • 191 Views
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Article
Tumor-specific delivery of therapeutic siRNAs by anti-EGFR immunonanoparticles
Jung Seok Kim, Min Woo Kim, Seong Jae Kang, Hwa Yeon Jeong, Sang Il Park, Yeon Kyung Lee, Hong Sung Kim, Keun Sik Kim & Yong Serk Park
Pages: 4817-4830
Published online: 27 Aug 2018
AbstractforTumor-specific delivery of therapeutic siRNAs by anti-EGFR immunonanoparticles | Full Text | References | PDF (2.7 MB)
  • 52 Views
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Article
Icariin-loaded electrospun PCL/gelatin sub-microfiber mat for preventing epidural adhesions after laminectomy
Yuelong Huang, Rui Shi, Min Gong, Jingshuang Zhang, Weiyang Li, Qingpeng Song, Chengai Wu & Wei Tian
Pages: 4831-4844
Published online: 27 Aug 2018
AbstractforIcariin-loaded electrospun PCL/gelatin sub-microfiber mat for preventing epidural adhesions after laminectomy | Full Text | References | PDF (2.8 MB)
  • 123 Views
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Corrigendum

Correction
Treatment of a multiple sclerosis animal model by a novel nanodrop formulation of a natural antioxidant [Corrigendum]
Page: 4845
Published online: 29 Aug 2018
CitationforTreatment of a multiple sclerosis animal model by a novel nanodrop formulation of a natural antioxidant [Corrigendum] | Full Text | PDF (140.8 KB)
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Original Research

Article
Anticancer activity of paclitaxel-loaded keratin nanoparticles in two-dimensional and perfused three-dimensional breast cancer models
Federica Foglietta, Giulio C Spagnoli, Manuele Giuseppe Muraro, Marco Ballestri, Andrea Guerrini, Claudia Ferroni, Annalisa Aluigi, Giovanna Sotgiu & Greta Varchi
Pages: 4847-4867
Published online: 29 Aug 2018
AbstractforAnticancer activity of paclitaxel-loaded keratin nanoparticles in two-dimensional and perfused three-dimensional breast cancer models | Full Text | References | PDF (8.3 MB)
  • 174 Views
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Article
Antitumor effect of gemcitabine-loaded albumin nanoparticle on gemcitabine-resistant pancreatic cancer induced by low hENT1 expression
Zhongyi Guo, Feng Wang, Yang Di, Lie Yao, Xinzhe Yu, Deliang Fu, Ji Li & Chen Jin
Pages: 4869-4880
Published online: 29 Aug 2018
AbstractforAntitumor effect of gemcitabine-loaded albumin nanoparticle on gemcitabine-resistant pancreatic cancer induced by low hENT1 expression | Full Text | References | PDF (5.1 MB)
  • 114 Views
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Article
Low-molecular-weight sulfonated chitosan as template for anticoagulant nanoparticles
Katja Heise, Mathias Hobisch, Liviu Sacarescu, Uros Maver, Josefine Hobisch, Tobias Reichelt, Marija Sega, Steffen Fischer, Stefan Spirk & Members of EPNOE and NAWI Graz
Pages: 4881-4894
Published online: 30 Aug 2018
AbstractforLow-molecular-weight sulfonated chitosan as template for anticoagulant nanoparticles | Full Text | References | PDF (2 MB)
  • 83 Views
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Article
Macropinocytosis activated by oncogenic Dbl enables specific targeted delivery of Tat/pDNA nano-complexes into ovarian cancer cells
Xiuran Niu, Zhihui Gao, Shanshan Qi, Linjia Su, Nan Yang, Xiuli Luan, Jia Li, Qing Zhang, Yingli An & Sihe Zhang
Pages: 4895-4911
Published online: 30 Aug 2018
AbstractforMacropinocytosis activated by oncogenic Dbl enables specific targeted delivery of Tat/pDNA nano-complexes into ovarian cancer cells | Full Text | References | PDF (10.2 MB)
  • 63 Views
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Article
Studies of acute and subchronic systemic toxicity associated with a copper/low-density polyethylene nanocomposite intrauterine device
Li-Xia Hu, Shi-Fu Hu, Meng Rao, Jing Yang, Hui Lei, Zhuo Duan, Wei Xia & Changhong Zhu
Pages: 4913-4926
Published online: 31 Aug 2018
AbstractforStudies of acute and subchronic systemic toxicity associated with a copper/low-density polyethylene nanocomposite intrauterine device | Full Text | References | PDF (10.3 MB)
  • 178 Views
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Article
Mangosteen pericarp extract embedded in electrospun PVP nanofiber mats: physicochemical properties and release mechanism of α-mangostin
Ida Sriyanti, Dhewa Edikresnha, Annisa Rahma, Muhammad Miftahul Munir, Heni Rachmawati & Khairurrijal Khairurrijal
Pages: 4927-4941
Published online: 31 Aug 2018
AbstractforMangosteen pericarp extract embedded in electrospun PVP nanofiber mats: physicochemical properties and release mechanism of α-mangostin | Full Text | References | PDF (4.5 MB)
  • 284 Views
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Article
Layer-by-layer DNA films incorporating highly transfecting bioreducible poly(amido amine) and polyethylenimine for sequential gene delivery
Lingxiao Xie, Xiong Ding, Rachel Budry & Guangzhao Mao
Pages: 4943-4960
Published online: 31 Aug 2018
AbstractforLayer-by-layer DNA films incorporating highly transfecting bioreducible poly(amido amine) and polyethylenimine for sequential gene delivery | Full Text | References | PDF (12 MB)
  • 95 Views
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Article
Anti-EGFR-iRGD recombinant protein modified biomimetic nanoparticles loaded with gambogic acid to enhance targeting and antitumor ability in colorectal cancer treatment
Zhen Zhang, Hanqing Qian, Jie Huang, Huizi Sha, Hang Zhang, Lixia Yu, Baorui Liu, Dong Hua & Xiaoping Qian
Pages: 4961-4975
Published online: 31 Aug 2018
AbstractforAnti-EGFR-iRGD recombinant protein modified biomimetic nanoparticles loaded with gambogic acid to enhance targeting and antitumor ability in colorectal cancer treatment | Full Text | References | PDF (5.4 MB)
  • 133 Views
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Article
Surface-enhanced Raman spectroscopy of blood serum based on gold nanoparticles for tumor stages detection and histologic grades classification of oral squamous cell carcinoma
Lili Xue, Bing Yan, Yi Li, Yingyun Tan, Xianyang Luo & Min Wang
Pages: 4977-4986
Published online: 31 Aug 2018
AbstractforSurface-enhanced Raman spectroscopy of blood serum based on gold nanoparticles for tumor stages detection and histologic grades classification of oral squamous cell carcinoma | Full Text | References | PDF (1.8 MB)
  • 169 Views
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Article
Chitosan-polyvinyl alcohol nanoscale liquid film-forming system facilitates MRSA-infected wound healing by enhancing antibacterial and antibiofilm properties
Sha Yang, Yun Yang, Sixin Cui, Ziqi Feng, Yuzhi Du, Zhen Song, Yanan Tong, Liuyang Yang, Zelin Wang, Hao Zeng, Quanming Zou & Hongwu Sun
Pages: 4987-5002
Published online: 03 Sep 2018
AbstractforChitosan-polyvinyl alcohol nanoscale liquid film-forming system facilitates MRSA-infected wound healing by enhancing antibacterial and antibiofilm properties | Full Text | References | PDF (8.2 MB)
  • 177 Views
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Review

Review Article
Amphiphilic peptides as novel nanomaterials: design, self-assembly and application
Feng Qiu, Yongzhu Chen, Chengkang Tang & Xiaojun Zhao
Pages: 5003-5022
Published online: 03 Sep 2018
AbstractforAmphiphilic peptides as novel nanomaterials: design, self-assembly and application | Full Text | References | PDF (5.9 MB)
  • 171 Views
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Review Article
Natural product-based nanomedicines for wound healing purposes: therapeutic targets and drug delivery systems
Marziyeh Hajialyani, Devesh Tewari, Eduardo Sobarzo-Sánchez, Seyed Mohammad Nabavi, Mohammad Hosein Farzaei & Mohammad Abdollahi
Pages: 5023-5043
Published online: 03 Sep 2018
AbstractforNatural product-based nanomedicines for wound healing purposes: therapeutic targets and drug delivery systems | Full Text | References | PDF (1.7 MB)
  • 985 Views
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Original Research

Article
Micro-/nano-topography of selective laser melting titanium enhances adhesion and proliferation and regulates adhesion-related gene expressions of human gingival fibroblasts and human gingival epithelial cells
Ruogu Xu, Xiucheng Hu, Xiaolin Yu, Shuangquan Wan, Fan Wu, Jianglin Ouyang & Feilong Deng
Pages: 5045-5057
Published online: 04 Sep 2018
AbstractforMicro-/nano-topography of selective laser melting titanium enhances adhesion and proliferation and regulates adhesion-related gene expressions of human gingival fibroblasts and human gingival epithelial cells | Full Text | References | PDF (6.8 MB)
  • 143 Views
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Article
Amelioration effects of nanoencapsulated triterpenoids from petri dish-cultured Antrodia cinnamomea on reproductive function of diabetic male rats
Sabri Sudirman, Yuan-Hua Hsu, Athira Johnson, David Tsou & Zwe-Ling Kong
Pages: 5059-5073
Published online: 04 Sep 2018
AbstractforAmelioration effects of nanoencapsulated triterpenoids from petri dish-cultured Antrodia cinnamomea on reproductive function of diabetic male rats | Full Text | References | PDF (3.4 MB)
  • 137 Views
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Article
In vitro cellular localization and efficient accumulation of fluorescently tagged biomaterials from monodispersed chitosan nanoparticles for elucidation of controlled release pathways for drug delivery systems
Ummu Afiqah Hassan, Mohd Zobir Hussein, Noorjahan Banu Alitheen, Syazaira Arham Yahya Ariff & Mas Jaffri Masarudin
Pages: 5075-5095
Published online: 05 Sep 2018
AbstractforIn vitro cellular localization and efficient accumulation of fluorescently tagged biomaterials from monodispersed chitosan nanoparticles for elucidation of controlled release pathways for drug delivery systems | Full Text | References | PDF (7.6 MB)
  • 138 Views
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Article
In vitro molecular study of wound healing using biosynthesized bacteria nanocellulose/silver nanocomposite assisted by bioinformatics databases
Mona Moniri, Amin Boroumand Moghaddam, Susan Azizi, Raha Abdul Rahim, Saad Wan Zuhainis, Mohammad Navaderi & Rosfarizan Mohamad
Pages: 5097-5112
Published online: 12 Sep 2018
AbstractforIn vitro molecular study of wound healing using biosynthesized bacteria nanocellulose/silver nanocomposite assisted by bioinformatics databases | Full Text | References | PDF (13.8 MB)
  • 323 Views
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Article
Quercetin and doxorubicin co-delivery using mesoporous silica nanoparticles enhance the efficacy of gastric carcinoma chemotherapy
Jian Fang, Shangwu Zhang, Xiaofeng Xue, Xinguo Zhu, Shiduo Song, Bin Wang, Linhua Jiang, Mingde Qin, Hansi Liang & Ling Gao
Pages: 5113-5126
Published online: 06 Sep 2018
AbstractforQuercetin and doxorubicin co-delivery using mesoporous silica nanoparticles enhance the efficacy of gastric carcinoma chemotherapy | Full Text | References | PDF (3.8 MB)
  • 261 Views
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Article
RETRACTED ARTICLE: Synthesis and characterization of a novel peptide-grafted Cs and evaluation of its nanoparticles for the oral delivery of insulin, in vitro, and in vivo study
Ghullam Reza Barbari, Farid Dorkoosh, Mohsen Amini, Nika Bahari Javan, Mohammad Sharifzadeh, Fateme Atyabi, Saeed Balalaie, Niyousha Rafiee Tehrani & Morteza Rafiee Tehrani
Pages: 5127-5138
Published online: 06 Sep 2018
AbstractforRETRACTED ARTICLE: Synthesis and characterization of a novel peptide-grafted Cs and evaluation of its nanoparticles for the oral delivery of insulin, in vitro, and in vivo study | PDF (2.3 MB)
  • 14 Views
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Article
Folate-receptor-targeted laser-activable poly(lactide-co-glycolic acid) nanoparticles loaded with paclitaxel/indocyanine green for photoacoustic/ultrasound imaging and chemo/photothermal therapy
Fengqiu Liu, Yuli Chen, Yizhen Li, Yuan Guo, Yang Cao, Pan Li, Zhigang Wang, Yuping Gong & Haitao Ran
Pages: 5139-5158
Published online: 06 Sep 2018
AbstractforFolate-receptor-targeted laser-activable poly(lactide-co-glycolic acid) nanoparticles loaded with paclitaxel/indocyanine green for photoacoustic/ultrasound imaging and chemo/photothermal therapy | Full Text | References | PDF (11.9 MB)
  • 152 Views
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Article
In vitro toxicity studies of biodegradable, polyelectrolyte nanocapsules
Alicja Karabasz, Krzysztof Szczepanowicz, Agnieszka Cierniak, Joanna Bereta & Monika Bzowska
Pages: 5159-5172
Published online: 06 Sep 2018
AbstractforIn vitro toxicity studies of biodegradable, polyelectrolyte nanocapsules | Full Text | References | PDF (5.1 MB)
  • 71 Views
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Article
Facilitated permeation of insulin across TR146 cells by cholic acid derivatives-modified elastic bilosomes
Santosh Bashyal, Jo-Eun Seo, Taekwang Keum, Gyubin Noh, Young Wook Choi & Sangkil Lee
Pages: 5173-5186
Published online: 06 Sep 2018
AbstractforFacilitated permeation of insulin across TR146 cells by cholic acid derivatives-modified elastic bilosomes | Full Text | References | PDF (2.3 MB)
  • 137 Views
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Article
Anti-JNK2 peptide–siRNA nanostructures improve plaque endothelium and reduce thrombotic risk in atherosclerotic mice
Hua Pan, Rohun U Palekar, Kirk K Hou, John Bacon, Huimin Yan, Luke E Springer, Antonina Akk, Lihua Yang, Mark J Miller, Christine TN Pham, Paul H Schlesinger & Samuel A Wickline
Pages: 5187-5205
Published online: 06 Sep 2018
AbstractforAnti-JNK2 peptide–siRNA nanostructures improve plaque endothelium and reduce thrombotic risk in atherosclerotic mice | Full Text | References | PDF (5 MB)
  • 97 Views
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Article
Effect of melanin on gold nanoparticle-induced hepatotoxicity and lipid peroxidation in rats
Mohamed Anwar K Abdelhalim, Sherif A Abdelmottaleb Moussa, Huda AY Qaid & Mohammed Suliman Al-Ayed
Pages: 5207-5213
Published online: 06 Sep 2018
AbstractforEffect of melanin on gold nanoparticle-induced hepatotoxicity and lipid peroxidation in rats | Full Text | References | PDF (1.2 MB)
  • 68 Views
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Article
Design of a transdermal formulation containing raloxifene nanoparticles for osteoporosis treatment
Noriaki Nagai, Fumihiko Ogata, Hiroko Otake, Yosuke Nakazawa & Naohito Kawasaki
Pages: 5215-5229
Published online: 06 Sep 2018
AbstractforDesign of a transdermal formulation containing raloxifene nanoparticles for osteoporosis treatment | Full Text | References | PDF (1.7 MB)
  • 242 Views
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Article
Mesenchymal stem cells loaded with paclitaxel-poly(lactic-co-glycolic acid) nanoparticles for glioma-targeting therapy
Xiaoling Wang, Jianqing Gao, Xumei Ouyang, Junbo Wang, Xiaoyi Sun & Yuanyuan Lv
Pages: 5231-5248
Published online: 07 Sep 2018
AbstractforMesenchymal stem cells loaded with paclitaxel-poly(lactic-co-glycolic acid) nanoparticles for glioma-targeting therapy | Full Text | References | PDF (5.1 MB)
  • 135 Views
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Short Report

Brief Report
Synthesis of multivalent polymer–aptamer conjugates with enhanced inhibitory potency
Jacob T Martin, Marc Douaisi, Ammar Arsiwala, Manish Arha & Ravi S Kane
Pages: 5249-5253
Published online: 07 Sep 2018
AbstractforSynthesis of multivalent polymer–aptamer conjugates with enhanced inhibitory potency | Full Text | References | PDF (1.6 MB)
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Corrigendum

Correction
Preparation of chitin-amphipathic anion/quaternary ammonium salt ecofriendly dressing and its effect on wound healing in mice [Corrigendum]
Page: 5255
Published online: 07 Sep 2018
CitationforPreparation of chitin-amphipathic anion/quaternary ammonium salt ecofriendly dressing and its effect on wound healing in mice [Corrigendum] | Full Text | PDF (142.3 KB)
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Original Research

Article
A novel bacterial cellulose membrane immobilized with human umbilical cord mesenchymal stem cells-derived exosome prevents epidural fibrosis
Bo Wang, Peng Li, Lei Shangguan, Jun Ma, Kezheng Mao, Quan Zhang, Yiguo Wang, Zhongyang Liu & Keya Mao
Pages: 5257-5273
Published online: 28 Feb 2023
AbstractforA novel bacterial cellulose membrane immobilized with human umbilical cord mesenchymal stem cells-derived exosome prevents epidural fibrosis | Full Text | References | PDF (21.1 MB)
  • 174 Views
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Article
The effects of amine-modified single-walled carbon nanotubes on the mouse microbiota
J Justin Mulvey, Eric R Littmann, Lilan Ling, Michael R McDevitt, Eric G Pamer & David A Scheinberg
Pages: 5275-5286
Published online: 28 Feb 2023
AbstractforThe effects of amine-modified single-walled carbon nanotubes on the mouse microbiota | Full Text | References | PDF (3 MB)
  • 46 Views
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Article
Electrospun PCL/mupirocin and chitosan/lidocaine hydrochloride multifunctional double layer nanofibrous scaffolds for wound dressing applications
Xiaoming Li, Chao Wang, Shuang Yang, Ping Liu & Bo Zhang
Pages: 5287-5299
Published online: 10 Sep 2018
AbstractforElectrospun PCL/mupirocin and chitosan/lidocaine hydrochloride multifunctional double layer nanofibrous scaffolds for wound dressing applications | Full Text | References | PDF (3.8 MB)
  • 345 Views
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Article
A novel microfluidic liposomal formulation for the delivery of the SN-38 camptothecin: characterization and in vitro assessment of its cytotoxic effect on two tumor cell lines
Ana Casadó, M Lluïsa Sagristá & Margarita Mora
Pages: 5301-5320
Published online: 11 Sep 2018
AbstractforA novel microfluidic liposomal formulation for the delivery of the SN-38 camptothecin: characterization and in vitro assessment of its cytotoxic effect on two tumor cell lines | Full Text | References | PDF (2.4 MB)
  • 121 Views
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Article
In situ exploration of characteristics of macropinocytosis and size range of internalized substances in cells by 3D-structured illumination microscopy
Jing Jin, Yanting Shen, Biao Zhang, Rong Deng, Dianshuai Huang, Tianqi Lu, Fei Sun, Shuping Xu & Chongyang Liang
Pages: 5321-5333
Published online: 12 Sep 2018
AbstractforIn situ exploration of characteristics of macropinocytosis and size range of internalized substances in cells by 3D-structured illumination microscopy | Full Text | References | PDF (7.7 MB)
  • 51 Views
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Article
Effect of young exosomes injected in aged mice
Bo-Ram Lee, Jung-Hee Kim, Eun-Sook Choi, Jung-Hoon Cho & Eunjoo Kim
Pages: 5335-5345
Published online: 28 Feb 2023
AbstractforEffect of young exosomes injected in aged mice | Full Text | References | PDF (1.9 MB)
  • 265 Views
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Article
Lipid insertion enables targeted functionalization of paclitaxel-loaded erythrocyte membrane nanosystem by tumor-penetrating bispecific recombinant protein
Hong Chen, Huizi Sha, Lianru Zhang, Hanqing Qian, Fangjun Chen, Naiqin Ding, Liulian Ji, Anqing Zhu, Qiuping Xu, Fanyan Meng, Lixia Yu, Yan Zhou & Baorui Liu
Pages: 5347-5359
Published online: 11 Sep 2018
AbstractforLipid insertion enables targeted functionalization of paclitaxel-loaded erythrocyte membrane nanosystem by tumor-penetrating bispecific recombinant protein | Full Text | References | PDF (3.4 MB)
  • 172 Views
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Article
Modification of the surface of titanium with multifunctional chimeric peptides to prevent biofilm formation via inhibition of initial colonizers
Xi Zhang, Hongjuan Geng, Lei Gong, Qian Zhang, Hongjie Li, Xu Zhang, Yonglan Wang & Ping Gao
Pages: 5361-5375
Published online: 12 Sep 2018
AbstractforModification of the surface of titanium with multifunctional chimeric peptides to prevent biofilm formation via inhibition of initial colonizers | Full Text | References | PDF (18.8 MB)
  • 73 Views
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Article
Monitoring local delivery of vancomycin from gelatin nanospheres in zebrafish larvae
Xiaolin Zhang, Jiankang Song, Alexey Klymov, Yang Zhang, Leonie de Boer, John A Jansen, Jeroen JJP van den Beucken, Fang Yang, Sebastian AJ Zaat & Sander CG Leeuwenburgh
Pages: 5377-5394
Published online: 13 Sep 2018
AbstractforMonitoring local delivery of vancomycin from gelatin nanospheres in zebrafish larvae | Full Text | References | PDF (11.6 MB)
  • 101 Views
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Article
Establishment of a novel homogeneous nanoparticle-based assay for sensitive procalcitonin detection of ultra low-volume serum samples
Peng Li, Zhenhua Chen, Bing Liu, Kun Li, Hao Wang, Li Lin, Ling He, Jie Wei & Tiancai Liu
Pages: 5395-5404
Published online: 13 Sep 2018
AbstractforEstablishment of a novel homogeneous nanoparticle-based assay for sensitive procalcitonin detection of ultra low-volume serum samples | Full Text | References | PDF (2.9 MB)
  • 83 Views
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Article
Novel silk fibroin nanoparticles incorporated silk fibroin hydrogel for inhibition of cancer stem cells and tumor growth
Puyuan Wu, Qin Liu, Qin Wang, Hanqing Qian, Lixia Yu, Baorui Liu & Rutian Li
Pages: 5405-5418
Published online: 17 Sep 2018
AbstractforNovel silk fibroin nanoparticles incorporated silk fibroin hydrogel for inhibition of cancer stem cells and tumor growth | Full Text | References | PDF (4.1 MB)
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Review

Review Article
Main trends of immune effects triggered by nanomedicines in preclinical studies
Blanka Halamoda-Kenzaoui & Susanne Bremer-Hoffmann
Pages: 5419-5431
Published online: 17 Sep 2018
AbstractforMain trends of immune effects triggered by nanomedicines in preclinical studies | Full Text | References | PDF (1.5 MB)
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Original Research

Article
3D-printed scaffolds of mesoporous bioglass/gliadin/polycaprolactone ternary composite for enhancement of compressive strength, degradability, cell responses and new bone tissue ingrowth
Yiqun Zhang, Wei Yu, Zhaoyu Ba, Shusen Cui, Jie Wei & Hong Li
Pages: 5433-5447
Published online: 17 Sep 2018
Abstractfor3D-printed scaffolds of mesoporous bioglass/gliadin/polycaprolactone ternary composite for enhancement of compressive strength, degradability, cell responses and new bone tissue ingrowth | Full Text | References | PDF (7.2 MB)
  • 126 Views
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Article
Pilot study on biocompatibility of fluorescent nanodiamond-(NV)-Z~800 particles in rats: safety, pharmacokinetics, and bio-distribution (part III)
Frank C Barone, Cezary Marcinkiewicz, Jie Li, Mark Sternberg, Peter I Lelkes, Dmitriy A Dikin, Peter J Bergold, Jonathan A Gerstenhaber & Giora Feuerstein
Pages: 5449-5468
Published online: 17 Sep 2018
AbstractforPilot study on biocompatibility of fluorescent nanodiamond-(NV)-Z~800 particles in rats: safety, pharmacokinetics, and bio-distribution (part III) | Full Text | References | PDF (13.5 MB)
  • 100 Views
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Article
Preparation of honokiol nanoparticles by liquid antisolvent precipitation technique, characterization, pharmacokinetics, and evaluation of inhibitory effect on HepG2 cells
Weiwei Wu, Li Wang, Lingling Wang, Yuangang Zu, Siying Wang, Peiyan Liu & Xiuhua Zhao
Pages: 5469-5483
Published online: 17 Sep 2018
AbstractforPreparation of honokiol nanoparticles by liquid antisolvent precipitation technique, characterization, pharmacokinetics, and evaluation of inhibitory effect on HepG2 cells | Full Text | References | PDF (2.7 MB)
  • 137 Views
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Article
Evaluation and characterization of waterborne biodegradable polyurethane films for the prevention of tendon postoperative adhesion
Shan-hui Hsu, Lien-Guo Dai, Yu-Min Hung & Niann-Tzyy Dai
Pages: 5485-5497
Published online: 17 Sep 2018
AbstractforEvaluation and characterization of waterborne biodegradable polyurethane films for the prevention of tendon postoperative adhesion | Full Text | References | PDF (5.4 MB)
  • 161 Views
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Article
Iron–gold alloy nanoparticles serve as a cornerstone in hyperthermia-mediated controlled drug release for cancer therapy
Yun-Qian Li, Meng Xu, Udesh Dhawan, Wai-Ching Liu, Kou-Ting Wu, Xin-Rui Liu, Chingpo Lin, Gang Zhao, Yu-Chuan Wu & Ren-Jei Chung
Pages: 5499-5509
Published online: 28 Feb 2023
AbstractforIron–gold alloy nanoparticles serve as a cornerstone in hyperthermia-mediated controlled drug release for cancer therapy | Full Text | References | PDF (3.6 MB)
  • 106 Views
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Review

Review Article
Multivalent nanosystems: targeting monocytes/macrophages
Rémy Poupot, Cécile Goursat & Séverine Fruchon
Pages: 5511-5521
Published online: 19 Sep 2018
AbstractforMultivalent nanosystems: targeting monocytes/macrophages | Full Text | References | PDF (596.9 KB)
  • 59 Views
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Original Research

Article
A novel absorption spectrometric method, based on graphene nanomaterials, for detection of hepatocellular carcinoma-specific T lymphocyte cells
Jianmeng Zhu, Yiping Li, Lei Li, Jian Wang, Hongqin Wang, Wenzhong Hong, Ke Hao, Yadan Xue, Bingyu Chen & Zhen Wang
Pages: 5523-5536
Published online: 19 Sep 2018
AbstractforA novel absorption spectrometric method, based on graphene nanomaterials, for detection of hepatocellular carcinoma-specific T lymphocyte cells | Full Text | References | PDF (3.3 MB)
  • 87 Views
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Article
Deepened cellular/subcellular interface penetration and enhanced antitumor efficacy of cyclic peptidic ligand-decorated accelerating active targeted nanomedicines
Nian-Qiu Shi, Yan Li, Yong Zhang, Zheng-Qiang Li & Xian-Rong Qi
Pages: 5537-5559
Published online: 19 Sep 2018
AbstractforDeepened cellular/subcellular interface penetration and enhanced antitumor efficacy of cyclic peptidic ligand-decorated accelerating active targeted nanomedicines | Full Text | References | PDF (8.4 MB)
  • 54 Views
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Review

Review Article
Theranostic applications of nanoparticles in neurodegenerative disorders
Sahana Ramanathan, Govindaraju Archunan, Muthusamy Sivakumar, Subramanian Tamil Selvan, A Lenin Fred, Sundramurthy Kumar, Balázs Gulyás & Parasuraman Padmanabhan
Pages: 5561-5576
Published online: 20 Sep 2018
AbstractforTheranostic applications of nanoparticles in neurodegenerative disorders | Full Text | References | PDF (2.5 MB)
  • 350 Views
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Original Research

Article
PPARγ agonist-loaded PLGA-PEG nanocarriers as a potential treatment for Alzheimer’s disease: in vitro and in vivo studies
Marcelle Silva-Abreu, Ana Cristina Calpena, Pol Andrés-Benito, Ester Aso, Ignacio A Romero, David Roig-Carles, Radka Gromnicova, Marta Espina, Isidre Ferrer, María Luisa García & David Male
Pages: 5577-5590
Published online: 20 Sep 2018
AbstractforPPARγ agonist-loaded PLGA-PEG nanocarriers as a potential treatment for Alzheimer’s disease: in vitro and in vivo studies | Full Text | References | PDF (3.7 MB)
  • 197 Views
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Article
Botryococcus braunii as a bioreactor for the production of nanoparticles with antimicrobial potentialities
Alejandra Arévalo-Gallegos, J Saul Garcia-Perez, Danay Carrillo-Nieves, RA Ramirez-Mendoza, Hafiz MN Iqbal & Roberto Parra-Saldívar
Pages: 5591-5604
Published online: 20 Sep 2018
AbstractforBotryococcus braunii as a bioreactor for the production of nanoparticles with antimicrobial potentialities | Full Text | References | PDF (3.7 MB)
  • 109 Views
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Article
The epigenetic mechanisms of nanotopography-guided osteogenic differentiation of mesenchymal stem cells via high-throughput transcriptome sequencing
Longwei Lv, Yunsong Liu, Ping Zhang, Xiangsong Bai, Xiaohan Ma, Yuejun Wang, Hongyi Li, Li Wang & Yongsheng Zhou
Pages: 5605-5623
Published online: 20 Sep 2018
AbstractforThe epigenetic mechanisms of nanotopography-guided osteogenic differentiation of mesenchymal stem cells via high-throughput transcriptome sequencing | Full Text | References | PDF (6 MB)
  • 96 Views
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Article
Comparison of normal versus imiquimod-induced psoriatic skin in mice for penetration of drugs and nanoparticles
Lin Sun, Zeyu Liu, Zibei Lin, Dongmei Cun, Henry HY Tong, Ru Yan, Ruibing Wang & Ying Zheng
Pages: 5625-5635
Published online: 21 Sep 2018
AbstractforComparison of normal versus imiquimod-induced psoriatic skin in mice for penetration of drugs and nanoparticles | Full Text | References | PDF (3.3 MB)
  • 192 Views
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Review

Review Article
Nanoparticles in tissue engineering: applications, challenges and prospects
Anwarul Hasan, Mahboob Morshed, Adnan Memic, Shabir Hassan, Thomas J Webster & Hany El-Sayed Marei
Pages: 5637-5655
Published online: 24 Sep 2018
AbstractforNanoparticles in tissue engineering: applications, challenges and prospects | Full Text | References | PDF (4.9 MB)
  • 1298 Views
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Original Research

Article
Effects of PEG surface density and chain length on the pharmacokinetics and biodistribution of methotrexate-loaded chitosan nanoparticles
Zaina Ait Bachir, YuKun Huang, MuYe He, Lei Huang, XinYu Hou, RongJun Chen & Feng Gao
Pages: 5657-5671
Published online: 24 Sep 2018
AbstractforEffects of PEG surface density and chain length on the pharmacokinetics and biodistribution of methotrexate-loaded chitosan nanoparticles | Full Text | References | PDF (2.6 MB)
  • 171 Views
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Article
Doxorubicin-loaded dextran-based nano-carriers for highly efficient inhibition of lymphoma cell growth and synchronous reduction of cardiac toxicity
Ying Fang, Hao Wang, Hong-Jing Dou, Xing Fan, Xiao-Chun Fei, Lei Wang, Shu Cheng, Anne Janin, Li Wang & Wei-Li Zhao
Pages: 5673-5683
Published online: 24 Sep 2018
AbstractforDoxorubicin-loaded dextran-based nano-carriers for highly efficient inhibition of lymphoma cell growth and synchronous reduction of cardiac toxicity | Full Text | References | PDF (6.2 MB)
  • 80 Views
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Article
Silver-doped graphene oxide nanocomposite triggers cytotoxicity and apoptosis in human hepatic normal and carcinoma cells
Daoud Ali, Saud Alarifi, Saad Alkahtani & Rafa S Almeer
Pages: 5685-5699
Published online: 24 Sep 2018
AbstractforSilver-doped graphene oxide nanocomposite triggers cytotoxicity and apoptosis in human hepatic normal and carcinoma cells | Full Text | References | PDF (3.2 MB)
  • 148 Views
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Article
A drug eluting poly(trimethylene carbonate)/poly(lactic acid)-reinforced nanocomposite for the functional delivery of osteogenic molecules
Xi Zhang, Mike A Geven, Xinluan Wang, Ling Qin, Dirk W Grijpma, Ton Peijs, David Eglin, Olivier Guillaume & Julien E Gautrot
Pages: 5701-5718
Published online: 24 Sep 2018
AbstractforA drug eluting poly(trimethylene carbonate)/poly(lactic acid)-reinforced nanocomposite for the functional delivery of osteogenic molecules | Full Text | References | PDF (5.4 MB)
  • 87 Views
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Article
Effects of core size and PEG coating layer of iron oxide nanoparticles on the distribution and metabolism in mice
Weiming Xue, Yanyan Liu, Na Zhang, Youdong Yao, Pei Ma, Huiyun Wen, Saipeng Huang, Yane Luo & Haiming Fan
Pages: 5719-5731
Published online: 25 Sep 2018
AbstractforEffects of core size and PEG coating layer of iron oxide nanoparticles on the distribution and metabolism in mice | Full Text | References | PDF (3.4 MB)
  • 213 Views
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Article
Determination of dose enhancement caused by AuNPs with Xoft® Axxent® Electronic (eBx™) and conventional brachytherapy: in vitro study
Elham Shahhoseini, Prabhakar Ramachandran, William Roy Patterson & Moshi Geso
Pages: 5733-5741
Published online: 25 Sep 2018
AbstractforDetermination of dose enhancement caused by AuNPs with Xoft® Axxent® Electronic (eBx™) and conventional brachytherapy: in vitro study | Full Text | References | PDF (1.4 MB)
  • 64 Views
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Article
Comparative effects of magnetic and water-based hyperthermia treatments on human osteosarcoma cells
Dumitru-Daniel Herea, Camelia Danceanu, Ecaterina Radu, Luminita Labusca, Nicoleta Lupu & Horia Chiriac
Pages: 5743-5751
Published online: 25 Sep 2018
AbstractforComparative effects of magnetic and water-based hyperthermia treatments on human osteosarcoma cells | Full Text | References | PDF (3.9 MB)
  • 75 Views
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Review

Review Article
Targeted nonviral gene therapy in prostate cancer
Najla Altwaijry, Sukrut Somani & Christine Dufès
Pages: 5753-5767
Published online: 25 Sep 2018
AbstractforTargeted nonviral gene therapy in prostate cancer | Full Text | References | PDF (908.7 KB)
  • 191 Views
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Corrigendum

Correction
Antioxidant and hepatoprotective role of selenium against silver nanoparticles [Corrigendum]
Page: 5769
Published online: 25 Sep 2018
CitationforAntioxidant and hepatoprotective role of selenium against silver nanoparticles [Corrigendum] | Full Text | PDF (142 KB)
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Original Research

Article
Carboxymethyl chitosan nanoparticles loaded with bioactive peptide OH-CATH30 benefit nonscar wound healing
Tongyi Sun, Bo Zhan, Weifen Zhang, Di Qin, Guixue Xia, Huijie Zhang, Meiyu Peng, Sheng-An Li, Yun Zhang, Yuanyuan Gao & Wen-Hui Lee
Pages: 5771-5786
Published online: 25 Sep 2018
AbstractforCarboxymethyl chitosan nanoparticles loaded with bioactive peptide OH-CATH30 benefit nonscar wound healing | Full Text | References | PDF (8.4 MB)
  • 201 Views
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Article
Restriction of H1N1 influenza virus infection by selenium nanoparticles loaded with ribavirin via resisting caspase-3 apoptotic pathway
Zhengfang Lin, Yinghua Li, Guifang Gong, Yu Xia, Changbing Wang, Yi Chen, Liang Hua, Jiayu Zhong, Ying Tang, Xiaomin Liu & Bing Zhu
Pages: 5787-5797
Published online: 26 Sep 2018
AbstractforRestriction of H1N1 influenza virus infection by selenium nanoparticles loaded with ribavirin via resisting caspase-3 apoptotic pathway | Full Text | References | PDF (5.6 MB)
  • 126 Views
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Article
Immunomodulatory properties of graphene oxide for osteogenesis and angiogenesis
Deting Xue, Erman Chen, Huiming Zhong, Wei Zhang, Shengdong Wang, Muhammad Umar Joomun, Tianyi Yao, Yanbin Tan, ShiSheng Lin, Qiang Zheng & Zhijun Pan
Pages: 5799-5810
Published online: 26 Sep 2018
AbstractforImmunomodulatory properties of graphene oxide for osteogenesis and angiogenesis | Full Text | References | PDF (2.9 MB)
  • 168 Views
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Article
Liposomal codelivery of an SN38 prodrug and a survivin siRNA for tumor therapy
Ye Bi, Robert J Lee, Xinyu Wang, Yating Sun, Mengqiao Wang, Lianlian Li, Chenliang Li, Jing Xie & Lesheng Teng
Pages: 5811-5822
Published online: 04 Oct 2018
AbstractforLiposomal codelivery of an SN38 prodrug and a survivin siRNA for tumor therapy | Full Text | References | PDF (4.9 MB)
  • 82 Views
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Article
Fluorescence properties of curcumin-loaded nanoparticles for cell tracking
Bassam Felipe Mogharbel, Julio Cesar Francisco, Ana Carolina Irioda, Dilcele Silva Moreira Dziedzic, Priscila Elias Ferreira, Daiany de Souza, Carolina Maria Costa Oliveira de Souza, Nelson Bergonse Neto, Luiz Cesar Guarita-Souza, Celia Regina Cavichiolo Franco, Celso Vataru Nakamura, Vanessa Kaplum, Letícia Mazzarino, Elenara Lemos-Senna, Redouane Borsali, Paula A Soto, Patricia Setton-Avruj, Eltyeb Abdelwahid & Katherine Athayde Teixeira de Carvalho
Pages: 5823-5836
Published online: 28 Sep 2018
AbstractforFluorescence properties of curcumin-loaded nanoparticles for cell tracking | Full Text | References | PDF (17.3 MB)
  • 135 Views
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Article
Hydrophobically modified chitosan nanoliposomes for intestinal drug delivery
M Gulrez Zariwala, Harshada Bendre, Anatoliy Markiv, Sebastien Farnaud, Derek Renshaw, Kevin MG Taylor & Satyanarayana Somavarapu
Pages: 5837-5848
Published online: 27 Sep 2018
AbstractforHydrophobically modified chitosan nanoliposomes for intestinal drug delivery | Full Text | References | PDF (2.3 MB)
  • 144 Views
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Article
Antibacterial and biodegradable tissue nano-adhesives for rapid wound closure
Meng-meng Lu, Jing Bai, Dan Shao, Jing Qiu, Ming Li, Xiao Zheng, Yun Xiao, Zheng Wang, Zhi-min Chang, Li Chen, Wen-fei Dong & Chun-bo Tang
Pages: 5849-5863
Published online: 27 Sep 2018
AbstractforAntibacterial and biodegradable tissue nano-adhesives for rapid wound closure | Full Text | References | PDF (10.9 MB)
  • 167 Views
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Article
Cationic graphene oxide nanoplatform mediates miR-101 delivery to promote apoptosis by regulating autophagy and stress
Akram Assali, Omid Akhavan, Fatemeh Mottaghitalab, Mohsen Adeli, Rassoul Dinarvand, Shayan Razzazan, Ehsan Arefian, Masoud Soleimani & Fatemeh Atyabi
Pages: 5865-5886
Published online: 01 Oct 2018
AbstractforCationic graphene oxide nanoplatform mediates miR-101 delivery to promote apoptosis by regulating autophagy and stress | Full Text | References | PDF (10.3 MB)
  • 65 Views
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Article
Self-nanoemulsifying drug delivery system of bruceine D: a new approach for anti-ulcerative colitis
Yao-Xing Dou, Jiang-Tao Zhou, Tong-Tong Wang, Yan-Feng Huang, Vicky Ping Chen, You-Liang Xie, Zhi-Xiu Lin, Jian-Sheng Gao, Zi-Ren Su & Hui-Fang Zeng
Pages: 5887-5907
Published online: 28 Sep 2018
AbstractforSelf-nanoemulsifying drug delivery system of bruceine D: a new approach for anti-ulcerative colitis | Full Text | References | PDF (13.1 MB)
  • 208 Views
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Article
Suppression of testosterone production by nanoparticulate TiO2 is associated with ERK1/2–PKA–PKC signaling pathways in rat primary cultured Leydig cells
Lingjuan Li, Xu Mu, Lingqun Ye, Yuguan Ze & Fashui Hong
Pages: 5909-5924
Published online: 28 Sep 2018
AbstractforSuppression of testosterone production by nanoparticulate TiO2 is associated with ERK1/2–PKA–PKC signaling pathways in rat primary cultured Leydig cells | Full Text | References | PDF (17.1 MB)
  • 73 Views
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Review

Review Article
Advanced nanomaterials targeting hypoxia to enhance radiotherapy
Jia Li, Wenting Shang, Yong Li, Sirui Fu, Jie Tian & Ligong Lu
Pages: 5925-5936
Published online: 01 Oct 2018
AbstractforAdvanced nanomaterials targeting hypoxia to enhance radiotherapy | Full Text | References | PDF (1.8 MB)
  • 131 Views
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Original Research

Article
A novel RGDyC/PEG co-modified PAMAM dendrimer-loaded arsenic trioxide of glioma targeting delivery system
Yanping Lu, Shunping Han, Hongyue Zheng, Rui Ma, Yuting Ping, Jiafeng Zou, Hongxia Tang, Yongping Zhang, Xiuling Xu & Fanzhu Li
Pages: 5937-5952
Published online: 02 Oct 2018
AbstractforA novel RGDyC/PEG co-modified PAMAM dendrimer-loaded arsenic trioxide of glioma targeting delivery system | Full Text | References | PDF (9.9 MB)
  • 75 Views
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Review

Review Article
A review of using green chemistry methods for biomaterials in tissue engineering
Hossein Jahangirian, Ensieh Ghasemian Lemraski, Roshanak Rafiee-Moghaddam & Thomas J Webster
Pages: 5953-5969
Published online: 04 Oct 2018
AbstractforA review of using green chemistry methods for biomaterials in tissue engineering | Full Text | References | PDF (3.5 MB)
  • 329 Views
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Original Research

Article
Prior anti-CAFs break down the CAFs barrier and improve accumulation of docetaxel micelles in tumor
Ning Pang, Ji Li, Aning Sun, Zhenzhen Yang, Shixuan Cheng & Xian-Rong Qi
Pages: 5971-5990
Published online: 04 Oct 2018
AbstractforPrior anti-CAFs break down the CAFs barrier and improve accumulation of docetaxel micelles in tumor | Full Text | References | PDF (10.8 MB)
  • 75 Views
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Article
Graphene quantum dots-gated hollow mesoporous carbon nanoplatform for targeting drug delivery and synergistic chemo-photothermal therapy
Junfeng Fang, Yanqing Liu, Yiwen Chen, Dimei Ouyang, Guangji Yang & Tao Yu
Pages: 5991-6007
Published online: 04 Oct 2018
AbstractforGraphene quantum dots-gated hollow mesoporous carbon nanoplatform for targeting drug delivery and synergistic chemo-photothermal therapy | Full Text | References | PDF (7.9 MB)
  • 245 Views
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Article
Transferrin and folic acid co-modified bufalin-loaded nanoliposomes: preparation, characterization, and application in anticancer activity
Qiankun Chen & Ji Liu
Pages: 6009-6018
Published online: 05 Oct 2018
AbstractforTransferrin and folic acid co-modified bufalin-loaded nanoliposomes: preparation, characterization, and application in anticancer activity | Full Text | References | PDF (2.2 MB)
  • 69 Views
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Article
Probing the intracellular refractive index and molecular interaction of gold nanoparticles in HeLa cells using single particle spectroscopy
Abu S M Mohsin & Mariam B Salim
Pages: 6019-6028
Published online: 04 Oct 2018
AbstractforProbing the intracellular refractive index and molecular interaction of gold nanoparticles in HeLa cells using single particle spectroscopy | Full Text | References | PDF (4 MB)
  • 100 Views
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Article
Identification of mycolic acid forms using surface-enhanced Raman scattering as a fast detection method for tuberculosis
Jayakumar Perumal, US Dinish, Anne K Bendt, Agne Kazakeviciute, Chit Yaw Fu, Irvine Lian Hao Ong & Malini Olivo
Pages: 6029-6038
Published online: 04 Oct 2018
AbstractforIdentification of mycolic acid forms using surface-enhanced Raman scattering as a fast detection method for tuberculosis | Full Text | References | PDF (2 MB)
  • 128 Views
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Article
Promoting vascular healing using nanofibrous ticagrelor-eluting stents
Cheng-Hung Lee, Ming-Jer Hsieh, Kuo-Sheng Liu, Che-Wei Cheng, Shang-Hung Chang, Shih-Jung Liu, Chao-Jan Wang, Ming-Yi Hsu, Kuo-Chun Hung, Yung-Hsin Yeh, Wei-Jan Chen, I-Chang Hsieh, Jyuhn-Huarng Juang & Ming-Shien Wen
Pages: 6039-6048
Published online: 05 Oct 2018
AbstractforPromoting vascular healing using nanofibrous ticagrelor-eluting stents | Full Text | References | PDF (3.7 MB)
  • 70 Views
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Review

Review Article
Overcoming tumor hypoxia as a barrier to radiotherapy, chemotherapy and immunotherapy in cancer treatment
Kaitlin Graham & Evan Unger
Pages: 6049-6058
Published online: 04 Oct 2018
AbstractforOvercoming tumor hypoxia as a barrier to radiotherapy, chemotherapy and immunotherapy in cancer treatment | Full Text | References | PDF (1.3 MB)
  • 579 Views
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Original Research

Article
Controlled quercetin release from high-capacity-loading hyperbranched polyglycerol-functionalized graphene oxide
Matin Islami, Ali Zarrabi, Seiichi Tada, Masuki Kawamoto, Takashi Isoshima & Yoshihiro Ito
Pages: 6059-6071
Published online: 05 Oct 2018
AbstractforControlled quercetin release from high-capacity-loading hyperbranched polyglycerol-functionalized graphene oxide | Full Text | References | PDF (2 MB)
  • 190 Views
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Article
Highly efficient transfection of human induced pluripotent stem cells using magnetic nanoparticles
Megan A Yamoah, Maryam Moshref, Janhavi Sharma, Wei Chun Chen, Hannah A Ledford, Jeong Han Lee, Karen S Chavez, Wenying Wang, Javier E López, Deborah K Lieu, Padmini Sirish & Xiao-Dong Zhang
Pages: 6073-6078
Published online: 28 Feb 2023
AbstractforHighly efficient transfection of human induced pluripotent stem cells using magnetic nanoparticles | Full Text | References | PDF (3.2 MB)
  • 196 Views
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Article
Different aggregation and shape characteristics of carbon materials affect biological responses in RAW264 cells
Chika Kuroda, Katsuya Ueda, Hisao Haniu, Haruka Ishida, Satomi Okano, Takashi Takizawa, Atsushi Sobajima, Takayuki Kamanaka, Kazushige Yoshida, Masanori Okamoto, Tamotsu Tsukahara, Yoshikazu Matsuda, Kaoru Aoki, Hiroyuki Kato & Naoto Saito
Pages: 6079-6088
Published online: 05 Oct 2018
AbstractforDifferent aggregation and shape characteristics of carbon materials affect biological responses in RAW264 cells | Full Text | References | PDF (2.7 MB)
  • 63 Views
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Article
In vitro evaluation of the antitumor effect of bismuth lipophilic nanoparticles (BisBAL NPs) on breast cancer cells
Rene Hernandez-Delgadillo, Claudia María García-Cuéllar, Yesennia Sánchez-Pérez, Nayely Pineda-Aguilar, Marco Antonio Martínez-Martínez, Eyra Elvyra Rangel-Padilla, Sergio Eduardo Nakagoshi-Cepeda, Juan Manuel Solís-Soto, Rosa Isela Sánchez-Nájera, María Argelia Akemi Nakagoshi-Cepeda, Shankararaman Chellam & Claudio Cabral-Romero
Pages: 6089-6097
Published online: 05 Oct 2018
AbstractforIn vitro evaluation of the antitumor effect of bismuth lipophilic nanoparticles (BisBAL NPs) on breast cancer cells | Full Text | References | PDF (1.7 MB)
  • 196 Views
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Article
A new SERS strategy for quantitative analysis of trace microalbuminuria based on immunorecognition and graphene oxide nanoribbon catalysis
Guiqing Wen, Qi Jing, Aihui Liang & Zhiliang Jiang
Pages: 6099-6107
Published online: 05 Oct 2018
AbstractforA new SERS strategy for quantitative analysis of trace microalbuminuria based on immunorecognition and graphene oxide nanoribbon catalysis | Full Text | References | PDF (1.7 MB)
  • 70 Views
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Review

Review Article
Microfluidization trends in the development of nanodelivery systems and applications in chronic disease treatments
Palanivel Ganesan, Govindarajan Karthivashan, Shin Young Park, Joonsoo Kim & Dong-Kug Choi
Pages: 6109-6121
Published online: 09 Oct 2018
AbstractforMicrofluidization trends in the development of nanodelivery systems and applications in chronic disease treatments | Full Text | References | PDF (2.2 MB)
  • 238 Views
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Original Research

Article
Argon plasma improves the tissue integration and angiogenesis of subcutaneous implants by modifying surface chemistry and topography
Michelle Griffin, Robert Palgrave, Víctor G Baldovino-Medrano, Peter E Butler & Deepak M Kalaskar
Pages: 6123-6141
Published online: 08 Oct 2018
AbstractforArgon plasma improves the tissue integration and angiogenesis of subcutaneous implants by modifying surface chemistry and topography | Full Text | References | PDF (16.5 MB)
  • 87 Views
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Review

Review Article
Nanotechnology, from quantum mechanical calculations up to drug delivery
Beata Szefler
Pages: 6143-6176
Published online: 09 Oct 2018
AbstractforNanotechnology, from quantum mechanical calculations up to drug delivery | Full Text | References | PDF (15.1 MB)
  • 211 Views
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Original Research

Article
MnO nanoparticles with potential application in magnetic resonance imaging and drug delivery for myocardial infarction
Yuanyuan Zheng, Hong Zhang, Yuping Hu, Lu Bai & Jingyi Xue
Pages: 6177-6188
Published online: 08 Oct 2018
AbstractforMnO nanoparticles with potential application in magnetic resonance imaging and drug delivery for myocardial infarction | Full Text | References | PDF (2.9 MB)
  • 109 Views
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Article
Pure paclitaxel nanoparticles: preparation, characterization, and antitumor effect for human liver cancer SMMC-7721 cells
Chao Wu, Yu Gao, Ying Liu & XiaoYan Xu
Pages: 6189-6198
Published online: 09 Oct 2018
AbstractforPure paclitaxel nanoparticles: preparation, characterization, and antitumor effect for human liver cancer SMMC-7721 cells | Full Text | References | PDF (6.4 MB)
  • 91 Views
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Article
Synthesis and study of cell-penetrating peptide-modified gold nanoparticles
Félix Boussoufi, Sandra M Navarro Gallón, Run Chang & Thomas Jay Webster
Pages: 6199-6205
Published online: 09 Oct 2018
AbstractforSynthesis and study of cell-penetrating peptide-modified gold nanoparticles | Full Text | References | PDF (1.8 MB)
  • 88 Views
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Article
Gold nanoparticles enhance cisplatin delivery and potentiate chemotherapy by decompressing colorectal cancer vessels
Xiaoxu Zhao, Jinghua Pan, Wei Li, Wende Yang, Li Qin & Yunlong Pan
Pages: 6207-6221
Published online: 09 Oct 2018
AbstractforGold nanoparticles enhance cisplatin delivery and potentiate chemotherapy by decompressing colorectal cancer vessels | Full Text | References | PDF (13.2 MB)
  • 122 Views
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Article
Laminin functionalized biomimetic apatite to regulate the adhesion and proliferation behaviors of neural stem cells
Dandan Luo, Shichao Ruan, Aiping Liu, Xiangdong Kong, In-Seop Lee & Cen Chen
Pages: 6223-6233
Published online: 09 Oct 2018
AbstractforLaminin functionalized biomimetic apatite to regulate the adhesion and proliferation behaviors of neural stem cells | Full Text | References | PDF (4.4 MB)
  • 74 Views
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Article
Nanocomposite plasters for the treatment of superficial tumors by chemo-photothermal combination therapy
Wei Qi, Jing Yan, Haifeng Sun & Hua Wang
Pages: 6235-6247
Published online: 09 Oct 2018
AbstractforNanocomposite plasters for the treatment of superficial tumors by chemo-photothermal combination therapy | Full Text | References | PDF (5.4 MB)
  • 63 Views
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Article
Synthesis of ginsenoside Re-based carbon dots applied for bioimaging and effective inhibition of cancer cells
Hua Yao, Jing Li, Yubin Song, Hong Zhao, Zhenhong Wei, Xiuying Li, Yongri Jin, Bai Yang & Jinlan Jiang
Pages: 6249-6264
Published online: 09 Oct 2018
AbstractforSynthesis of ginsenoside Re-based carbon dots applied for bioimaging and effective inhibition of cancer cells | Full Text | References | PDF (4.1 MB)
  • 177 Views
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Article
Polycaprolactone electrospun fiber scaffold loaded with iPSCs-NSCs and ASCs as a novel tissue engineering scaffold for the treatment of spinal cord injury
XianHu Zhou, GuiDong Shi, BaoYou Fan, Xin Cheng, XiaoLei Zhang, Xu Wang, Shen Liu, Yan Hao, ZhiJian Wei, LianYong Wang & ShiQing Feng
Pages: 6265-6277
Published online: 10 Oct 2018
AbstractforPolycaprolactone electrospun fiber scaffold loaded with iPSCs-NSCs and ASCs as a novel tissue engineering scaffold for the treatment of spinal cord injury | Full Text | References | PDF (11 MB)
  • 242 Views
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Review

Review Article
Drug delivery systems for elemene, its main active ingredient β-elemene, and its derivatives in cancer therapy
Bingtao Zhai, Yiying Zeng, Zhaowu Zeng, Nana Zhang, Chenxi Li, Yijun Zeng, Yu You, Shuling Wang, Xiabin Chen, Xinbing Sui & Tian Xie
Pages: 6279-6296
Published online: 10 Oct 2018
AbstractforDrug delivery systems for elemene, its main active ingredient β-elemene, and its derivatives in cancer therapy | Full Text | References | PDF (2.8 MB)
  • 256 Views
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Original Research

Article
Insights into the antibacterial mechanism of PEGylated nano-bacitracin A against Streptococcus pneumonia: both penicillin-sensitive and penicillin-resistant strains
Wei Hong, Lipeng Liu, Zehui Zhang, Yining Zhao, Dexian Zhang & Mingchun Liu
Pages: 6297-6309
Published online: 10 Oct 2018
AbstractforInsights into the antibacterial mechanism of PEGylated nano-bacitracin A against Streptococcus pneumonia: both penicillin-sensitive and penicillin-resistant strains | Full Text | References | PDF (4.8 MB)
  • 77 Views
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Article
Effect of quercetin-conjugated superparamagnetic iron oxide nanoparticles on diabetes-induced learning and memory impairment in rats
Shiva Ebrahimpour, Abolghasem Esmaeili & Siamak Beheshti
Pages: 6311-6324
Published online: 11 Oct 2018
AbstractforEffect of quercetin-conjugated superparamagnetic iron oxide nanoparticles on diabetes-induced learning and memory impairment in rats | Full Text | References | PDF (17.9 MB)
  • 206 Views
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Article
In situ misemgel as a multifunctional dual-absorption platform for nasal delivery of raloxifene hydrochloride: formulation, characterization, and in vivo performance
Osama AA Ahmed & Shaimaa M Badr-Eldin
Pages: 6325-6335
Published online: 11 Oct 2018
AbstractforIn situ misemgel as a multifunctional dual-absorption platform for nasal delivery of raloxifene hydrochloride: formulation, characterization, and in vivo performance | Full Text | References | PDF (4.3 MB)
  • 98 Views
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Article
Personalized nanomedicine: a rapid, sensitive, and selective UV–vis spectrophotometry method for the quantification of nanostructured PEG-asparaginase activity in children’s plasma
Yong Zhang, Yongren Wang, Ru Wang, Yan Shen, Jing Xu, Thomas J Webster & Yongjun Fang
Pages: 6337-6344
Published online: 15 Oct 2018
AbstractforPersonalized nanomedicine: a rapid, sensitive, and selective UV–vis spectrophotometry method for the quantification of nanostructured PEG-asparaginase activity in children’s plasma | Full Text | References | PDF (710.2 KB)
  • 105 Views
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Article
Involvement of complement activation in the pulmonary vasoactivity of polystyrene nanoparticles in pigs: unique surface properties underlying alternative pathway activation and instant opsonization
Tamás Mészáros, Gergely Tibor Kozma, Taro Shimizu, Koga Miyahara, Keren Turjeman, Tatsuhiro Ishida, Yechezkel Barenholz, Rudolf Urbanics & János Szebeni
Pages: 6345-6357
Published online: 11 Oct 2018
AbstractforInvolvement of complement activation in the pulmonary vasoactivity of polystyrene nanoparticles in pigs: unique surface properties underlying alternative pathway activation and instant opsonization | Full Text | References | PDF (3.1 MB)
  • 75 Views
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Article
Nanolayered composite with enhanced ultraviolet ray absorption properties from simultaneous intercalation of sunscreen molecules
Sumaiyah Megat Nabil Mohsin, Mohd Zobir Hussein, Siti Halimah Sarijo, Sharida Fakurazi, Palanisamy Arulselvan & Yun Hin Taufiq-Yap
Pages: 6359-6374
Published online: 28 Feb 2023
AbstractforNanolayered composite with enhanced ultraviolet ray absorption properties from simultaneous intercalation of sunscreen molecules | Full Text | References | PDF (4.6 MB)
  • 95 Views
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Article
Short duration cancer treatment: inspired by a fast bio-resorbable smart nano-fiber device containing NIR lethal polydopamine nanospheres for effective chemo–photothermal cancer therapy
Francis O Obiweluozor, Gladys A Emechebe, Arjun Prasad Tiwari, Ju Yeon Kim, Chan Hee Park & Cheol Sang Kim
Pages: 6375-6390
Published online: 12 Oct 2018
AbstractforShort duration cancer treatment: inspired by a fast bio-resorbable smart nano-fiber device containing NIR lethal polydopamine nanospheres for effective chemo–photothermal cancer therapy | Full Text | References | PDF (10.5 MB)
  • 129 Views
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Article
Biomimetic quantum dot-labeled B16F10 murine melanoma cells as a tool to monitor early steps of lung metastasis by in vivo imaging
Víctor Manuel Díaz-García, Simón Guerrero, Natalia Díaz-Valdivia, Lorena Lobos-González, Marcelo Kogan, José Manuel Pérez-Donoso & Andrew FG Quest
Pages: 6391-6412
Published online: 16 Oct 2018
AbstractforBiomimetic quantum dot-labeled B16F10 murine melanoma cells as a tool to monitor early steps of lung metastasis by in vivo imaging | Full Text | References | PDF (6 MB)
  • 93 Views
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Article
Photothermal exposure of polydopamine-coated branched Au–Ag nanoparticles induces cell cycle arrest, apoptosis, and autophagy in human bladder cancer cells
Xiaoming Zhao, Tianyang Qi, Chenfei Kong, Miao Hao, Yuqian Wang, Jing Li, Baocai Liu, Yiyao Gao & Jinlan Jiang
Pages: 6413-6428
Published online: 12 Oct 2018
AbstractforPhotothermal exposure of polydopamine-coated branched Au–Ag nanoparticles induces cell cycle arrest, apoptosis, and autophagy in human bladder cancer cells | Full Text | References | PDF (17.3 MB)
  • 129 Views
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Article
Cancer drug therapy and stochastic modeling of “nano-motors”
Lubna Sherin, Shabieh Farwa, Ayesha Sohail, Zhiwu Li & O Anwar Bég
Pages: 6429-6440
Published online: 15 Oct 2018
AbstractforCancer drug therapy and stochastic modeling of “nano-motors” | Full Text | References | PDF (2.6 MB)
  • 60 Views
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Article
Effect of CCR2 inhibitor-loaded lipid micelles on inflammatory cell migration and cardiac function after myocardial infarction
Jinli Wang, Min Jeong Seo, Michael B Deci, Brian R Weil, John M Canty & Juliane Nguyen
Pages: 6441-6451
Published online: 15 Oct 2018
AbstractforEffect of CCR2 inhibitor-loaded lipid micelles on inflammatory cell migration and cardiac function after myocardial infarction | Full Text | References | PDF (2.8 MB)
  • 127 Views
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Article
Nanohybrid hydrogels designed for transbuccal anesthesia
Lígia Nunes de Morais Ribeiro, Michelle Franz-Montan, Márcia Cristina Breitkreitz, Gustavo Henrique Rodrigues da Silva, Simone Ramos de Castro, Viviane Aparecida Guilherme, Daniele Ribeiro de Araújo & Eneida de Paula
Pages: 6453-6463
Published online: 15 Oct 2018
AbstractforNanohybrid hydrogels designed for transbuccal anesthesia | Full Text | References | PDF (5.3 MB)
  • 115 Views
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Article
Development of a kojic monooleate-enriched oil-in-water nanoemulsion as a potential carrier for hyperpigmentation treatment
Sharifah Nurfadhlin Afifah Syed Azhar, Siti Efliza Ashari & Norazlinaliza Salim
Pages: 6465-6479
Published online: 15 Oct 2018
AbstractforDevelopment of a kojic monooleate-enriched oil-in-water nanoemulsion as a potential carrier for hyperpigmentation treatment | Full Text | References | PDF (2 MB)
  • 283 Views
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Article
CAIX aptamer-functionalized targeted nanobubbles for ultrasound molecular imaging of various tumors
Lianhua Zhu, Luofu Wang, Yu Liu, Dan Xu, Kejing Fang & Yanli Guo
Pages: 6481-6495
Published online: 28 Feb 2023
AbstractforCAIX aptamer-functionalized targeted nanobubbles for ultrasound molecular imaging of various tumors | Full Text | References | PDF (6.8 MB)
  • 89 Views
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Corrigendum

Correction
Antibacterial properties and toxicity from metallic nanomaterials [Corrigendum]
Page: 6497
Published online: 16 Oct 2018
CitationforAntibacterial properties and toxicity from metallic nanomaterials [Corrigendum] | Full Text | PDF (144.4 KB)
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Original Research

Article
pH and redox dual-responsive copolymer micelles with surface charge reversal for co-delivery of all-trans-retinoic acid and paclitaxel for cancer combination chemotherapy
Yanqiu Zhang, Lianjun Peng, Jiahui Chu, Ming Zhang, Lizhu Sun, Bin Zhong & Qiyong Wu
Pages: 6499-6515
Published online: 16 Oct 2018
AbstractforpH and redox dual-responsive copolymer micelles with surface charge reversal for co-delivery of all-trans-retinoic acid and paclitaxel for cancer combination chemotherapy | Full Text | References | PDF (9.6 MB)
  • 134 Views
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Article
Inducing angiogenesis with the controlled release of nitric oxide from biodegradable and biocompatible copolymeric nanoparticles
Chungmo Yang, Hae Hyun Hwang, Soohyun Jeong, Deokwon Seo, Yoon Jeong, Dong Yun Lee & Kangwon Lee
Pages: 6517-6530
Published online: 28 Feb 2023
AbstractforInducing angiogenesis with the controlled release of nitric oxide from biodegradable and biocompatible copolymeric nanoparticles | Full Text | References | PDF (6.3 MB)
  • 158 Views
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Article
Coated electrospun alginate-containing fibers as novel delivery systems for regenerative purposes
Barbara Vigani, Silvia Rossi, Giuseppina Sandri, Maria Cristina Bonferoni, Giulia Milanesi, Giovanna Bruni & Franca Ferrari
Pages: 6531-6550
Published online: 17 Oct 2018
AbstractforCoated electrospun alginate-containing fibers as novel delivery systems for regenerative purposes | Full Text | References | PDF (10.7 MB)
  • 86 Views
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Review

Review Article
Hypoxia-activated prodrugs and redox-responsive nanocarriers
Yun Zeng, Jingwen Ma, Yonghua Zhan, Xinyi Xu, Qi Zeng, Jimin Liang & Xueli Chen
Pages: 6551-6574
Published online: 18 Oct 2018
AbstractforHypoxia-activated prodrugs and redox-responsive nanocarriers | Full Text | References | PDF (5.9 MB)
  • 194 Views
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Original Research

Article
Silver-coated gold nanorods as a promising antimicrobial agent in the treatment of cancer-related infections
Junyan Zhang, Mian Wang & Thomas J Webster
Pages: 6575-6583
Published online: 17 Oct 2018
AbstractforSilver-coated gold nanorods as a promising antimicrobial agent in the treatment of cancer-related infections | Full Text | References | PDF (7.4 MB)
  • 44 Views
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Article
Self-nanoemulsifying drug-delivery systems for potentiated anti-inflammatory activity of diacerein
Amal Ahmed Eltobshi, Elham Abdelmonem Mohamed, Galal Mahmoud Abdelghani & Ahmed Talaat Nouh
Pages: 6585-6602
Published online: 18 Oct 2018
AbstractforSelf-nanoemulsifying drug-delivery systems for potentiated anti-inflammatory activity of diacerein | Full Text | References | PDF (3.7 MB)
  • 167 Views
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Methodology

Article
Highly efficient siRNA transfection in macrophages using apoptotic body-mimic Ca-PS lipopolyplex
Yueyang Lai, Xuebo Xu, Zhenyu Zhu & Zichun Hua
Pages: 6603-6623
Published online: 24 Oct 2018
AbstractforHighly efficient siRNA transfection in macrophages using apoptotic body-mimic Ca-PS lipopolyplex | Full Text | References | PDF (8.3 MB)
  • 102 Views
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Original Research

Article
Evaluation of the internal fixation effect of nano-calcium-deficient hydroxyapatite/poly-amino acid composite screws for intraarticular fractures in rabbits
Zhenyu Dai, Yue Li, Yonggang Yan, Ruijie Wan, Qiang Ran, Weizhong Lu, Bo Qiao & Hong Li
Pages: 6625-6636
Published online: 28 Feb 2023
AbstractforEvaluation of the internal fixation effect of nano-calcium-deficient hydroxyapatite/poly-amino acid composite screws for intraarticular fractures in rabbits | Full Text | References | PDF (3.3 MB)
  • 66 Views
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Article
Protein nanoparticles with ligand-binding and enzymatic activities
Olga V Morozova, Elizaveta R Pavlova, Dmitry V Bagrov, Nikolay A Barinov, Kirill A Prusakov, Elena I Isaeva, Victor V Podgorsky, Dmitry V Basmanov & Dmitry V Klinov
Pages: 6637-6646
Published online: 18 Oct 2018
AbstractforProtein nanoparticles with ligand-binding and enzymatic activities | Full Text | References | PDF (2.3 MB)
  • 135 Views
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Article
Artificially controlled degradable nanoparticles for contrast switch MRI and programmed cancer therapy
Tianyang Yun, Yuxin Liu, Shaoqiong Yi, Qi Jia, Yang Liu & Jing Zhou
Pages: 6647-6659
Published online: 24 Oct 2018
AbstractforArtificially controlled degradable nanoparticles for contrast switch MRI and programmed cancer therapy | Full Text | References | PDF (5.5 MB)
  • 54 Views
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Article
pH-sensitive PEGylation of RIPL peptide-conjugated nanostructured lipid carriers: design and in vitro evaluation
Chang Hyun Kim, Cheol-Ki Sa, Min Su Goh, Eun Seok Lee, Tae Hoon Kang, Ho Yub Yoon, Gantumur Battogtokh, Young Tag Ko & Young Wook Choi
Pages: 6661-6675
Published online: 28 Feb 2023
AbstractforpH-sensitive PEGylation of RIPL peptide-conjugated nanostructured lipid carriers: design and in vitro evaluation | Full Text | References | PDF (2.3 MB)
  • 99 Views
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Article
From 3D spheroids to tumor bearing mice: efficacy and distribution studies of trastuzumab-docetaxel immunoliposome in breast cancer
Anne Rodallec, Guillaume Sicard, Sarah Giacometti, Manon Carré, Bertrand Pourroy, Fanny Bouquet, Ariel Savina, Bruno Lacarelle, Joseph Ciccolini & Raphaelle Fanciullino
Pages: 6677-6688
Published online: 23 Oct 2018
AbstractforFrom 3D spheroids to tumor bearing mice: efficacy and distribution studies of trastuzumab-docetaxel immunoliposome in breast cancer | Full Text | References | PDF (2.9 MB)
  • 127 Views
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Article
Magnetic resonance sentinel lymph node imaging and magnetometer-guided intraoperative detection in prostate cancer using superparamagnetic iron oxide nanoparticles
Alexander Winter, Tobias Kowald, Tina Susanne Paulo, Philipp Goos, Svenja Engels, Holger Gerullis, Jonas Schiffmann, Ajay Chavan & Friedhelm Wawroschek
Pages: 6689-6698
Published online: 28 Feb 2023
AbstractforMagnetic resonance sentinel lymph node imaging and magnetometer-guided intraoperative detection in prostate cancer using superparamagnetic iron oxide nanoparticles | Full Text | References | PDF (3.2 MB)
  • 61 Views
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Article
Liposomal nanoparticle-based conserved peptide influenza vaccine and monosodium urate crystal adjuvant elicit protective immune response in pigs
Santosh Dhakal, Xingguo Cheng, John Salcido, Sankar Renu, Kathy Bondra, Yashavantha Shaan Lakshmanappa, Christina Misch, Shristi Ghimire, Ninoshkaly Feliciano-Ruiz, Bradley Hogshead, Steven Krakowka, Kenneth Carson, Joseph McDonough, Chang Won Lee & Gourapura J Renukaradhya
Pages: 6699-6715
Published online: 24 Oct 2018
AbstractforLiposomal nanoparticle-based conserved peptide influenza vaccine and monosodium urate crystal adjuvant elicit protective immune response in pigs | Full Text | References | PDF (1.8 MB)
  • 137 Views
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Article
Amino acid composition of nanofibrillar self-assembling peptide hydrogels affects responses of periodontal tissue cells in vitro
Franziska Koch, Anne Wolff, Stephanie Mathes, Uwe Pieles, Sina S Saxer, Bernd Kreikemeyer & Kirsten Peters
Pages: 6717-6733
Published online: 23 Oct 2018
AbstractforAmino acid composition of nanofibrillar self-assembling peptide hydrogels affects responses of periodontal tissue cells in vitro | Full Text | References | PDF (3.3 MB)
  • 85 Views
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Article
Immunotoxicity of titanium dioxide nanoparticles via simultaneous induction of apoptosis and multiple toll-like receptors signaling through ROS-dependent SAPK/JNK and p38 MAPK activation
Madhusmita Dhupal, Jae-Min Oh, Dipti Ranjan Tripathy, Soo-Ki Kim, Sang Baek Koh & Kyu-Sang Park
Pages: 6735-6750
Published online: 23 Oct 2018
AbstractforImmunotoxicity of titanium dioxide nanoparticles via simultaneous induction of apoptosis and multiple toll-like receptors signaling through ROS-dependent SAPK/JNK and p38 MAPK activation | Full Text | References | PDF (8.1 MB)
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Article
Loading icariin on titanium surfaces by phase-transited lysozyme priming and layer-by-layer self-assembly of hyaluronic acid/chitosan to improve surface osteogenesis ability
Yunjia Song, Aobo Ma, Jia Ning, Xue Zhong, Qian Zhang, Xu Zhang, Guang Hong, Ying Li, Keiichi Sasaki & Changyi Li
Pages: 6751-6767
Published online: 23 Oct 2018
AbstractforLoading icariin on titanium surfaces by phase-transited lysozyme priming and layer-by-layer self-assembly of hyaluronic acid/chitosan to improve surface osteogenesis ability | Full Text | References | PDF (10.2 MB)
  • 101 Views
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Article
Decreased Porphyromonas gingivalis adhesion and improved biocompatibility on tetracycline-loaded TiO2 nanotubes: an in vitro study
Lei Sun, Jiliang Xu, Zihuan Sun, Fang Zheng, Chun Liu, Chao Wang, Xiaoye Hu, Lunguo Xia, Zhou Liu & Rong Xia
Pages: 6769-6777
Published online: 24 Oct 2018
AbstractforDecreased Porphyromonas gingivalis adhesion and improved biocompatibility on tetracycline-loaded TiO2 nanotubes: an in vitro study | Full Text | References | PDF (2.3 MB)
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Article
Plasma membrane is the target of rapid antibacterial action of silver nanoparticles in Escherichia coli and Pseudomonas aeruginosa
Olesja M Bondarenko, Mariliis Sihtmäe, Julia Kuzmičiova, Lina Ragelienė, Anne Kahru & Rimantas Daugelavičius
Pages: 6779-6790
Published online: 26 Oct 2018
AbstractforPlasma membrane is the target of rapid antibacterial action of silver nanoparticles in Escherichia coli and Pseudomonas aeruginosa | Full Text | References | PDF (2.2 MB)
  • 297 Views
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Article
The therapeutic effect in gliomas of nanobubbles carrying siRNA combined with ultrasound-targeted destruction
Wenbin Cai, Wei Lv, Yang Feng, Hengli Yang, Yajun Zhang, Guodong Yang, Yunyou Duan & Jia Wang
Pages: 6791-6807
Published online: 24 Oct 2018
AbstractforThe therapeutic effect in gliomas of nanobubbles carrying siRNA combined with ultrasound-targeted destruction | Full Text | References | PDF (8.7 MB)
  • 87 Views
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Article
Oridonin-loaded and GPC1-targeted gold nanoparticles for multimodal imaging and therapy in pancreatic cancer
Wenli Qiu, Rong Chen, Xiao Chen, Huifeng Zhang, Lina Song, Wenjing Cui, Jingjing Zhang, Dandan Ye, Yifen Zhang & Zhongqiu Wang
Pages: 6809-6827
Published online: 24 Oct 2018
AbstractforOridonin-loaded and GPC1-targeted gold nanoparticles for multimodal imaging and therapy in pancreatic cancer | Full Text | References | PDF (9.4 MB)
  • 346 Views
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Article
Chitosan-microcapsulated insulin alleviates mesenteric microcirculation dysfunction via modulating COX-2 and VCAM-1 expression in rats with diabetes mellitus
Jun Xu, Lijun Cao, Yuan Suo, Xiaoqin Xu, Hui Sun, Songao Xu, Xiangyun Zhu, Huijie Yu & Weizhong Cao
Pages: 6829-6837
Published online: 25 Oct 2018
AbstractforChitosan-microcapsulated insulin alleviates mesenteric microcirculation dysfunction via modulating COX-2 and VCAM-1 expression in rats with diabetes mellitus | Full Text | References | PDF (2.2 MB)
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Article
Gold nanorods/siRNA complex administration for knockdown of PARP-1: a potential treatment for perinatal asphyxia
Valentina Vio, Ana L Riveros, Andrea Tapia-Bustos, Carolyne Lespay-Rebolledo, Ronald Perez-Lobos, Luis Muñoz, Paola Pismante, Paola Morales, Eyleen Araya, Natalia Hassan, Mario Herrera-Marschitz & Marcelo J Kogan
Pages: 6839-6854
Published online: 28 Feb 2023
AbstractforGold nanorods/siRNA complex administration for knockdown of PARP-1: a potential treatment for perinatal asphyxia | Full Text | References | PDF (2.6 MB)
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Article
Codelivery of doxorubicin and elacridar to target both liver cancer cells and stem cells by polylactide-co-glycolide/d-alpha-tocopherol polyethylene glycol 1000 succinate nanoparticles
Dazhong Chen, Xiaoli Pan, Fangyuan Xie, Ying Lu, Hao Zou, Chuan Yin, Yu Zhang & Jie Gao
Pages: 6855-6870
Published online: 25 Oct 2018
AbstractforCodelivery of doxorubicin and elacridar to target both liver cancer cells and stem cells by polylactide-co-glycolide/d-alpha-tocopherol polyethylene glycol 1000 succinate nanoparticles | Full Text | References | PDF (3.6 MB)
  • 101 Views
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Article
Biophysical, bioinformatical, cellular, and molecular investigations on the effects of graphene oxide nanosheets on the hemoglobin structure and lymphocyte cell cytotoxicity
Mohammad Mahdi Nejadi Babadaei, Mina Feli Moghaddam, Sara Solhvand, Ehsan Alizadehmollayaghoob, Farnoosh Attar, Elham Rajabbeigi, Keivan Akhtari, Soyar Sari & Mojtaba Falahati
Pages: 6871-6884
Published online: 26 Oct 2018
AbstractforBiophysical, bioinformatical, cellular, and molecular investigations on the effects of graphene oxide nanosheets on the hemoglobin structure and lymphocyte cell cytotoxicity | Full Text | References | PDF (4.2 MB)
  • 83 Views
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Article
pH-responsive hybrid nanoparticle with enhanced dissociation characteristic for siRNA delivery
Menghao Shi, Xiufeng Zhao, Jiulong Zhang, Shuang Pan, Chunrong Yang, Ying Wei, Haiyang Hu, Mingxi Qiao, Dawei Chen & Xiuli Zhao
Pages: 6885-6902
Published online: 26 Oct 2018
AbstractforpH-responsive hybrid nanoparticle with enhanced dissociation characteristic for siRNA delivery | Full Text | References | PDF (7.4 MB)
  • 51 Views
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Article
Ultrasmall superparamagnetic Fe3O4 nanoparticles: honey-based green and facile synthesis and in vitro viability assay
Elisa Rasouli, Wan Jeffrey Basirun, Majid Rezayi, Kamyar Shameli, Esmail Nourmohammadi, Roshanak Khandanlou, Zahra Izadiyan & Hoda Khoshdel Sarkarizi
Pages: 6903-6911
Published online: 26 Oct 2018
AbstractforUltrasmall superparamagnetic Fe3O4 nanoparticles: honey-based green and facile synthesis and in vitro viability assay | Full Text | References | PDF (2.7 MB)
  • 181 Views
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Article
Peptide T7-modified polypeptide with disulfide bonds for targeted delivery of plasmid DNA for gene therapy of prostate cancer
Yue Lu, Wenjun Jiang, Xin Wu, Saixu Huang, Zhiyong Huang, Yamin Shi, Qi Dai, Jianming Chen, Fuzheng Ren & Shen Gao
Pages: 6913-6927
Published online: 30 Oct 2018
AbstractforPeptide T7-modified polypeptide with disulfide bonds for targeted delivery of plasmid DNA for gene therapy of prostate cancer | Full Text | References | PDF (10.1 MB)
  • 70 Views
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Article
Functionalized selenium nanoparticles for targeted delivery of doxorubicin to improve non-small-cell lung cancer therapy
Yu Xia, Yi Chen, Liang Hua, Mingqi Zhao, Tiantian Xu, Changbing Wang, Yinghua Li & Bing Zhu
Pages: 6929-6939
Published online: 30 Oct 2018
AbstractforFunctionalized selenium nanoparticles for targeted delivery of doxorubicin to improve non-small-cell lung cancer therapy | Full Text | References | PDF (3.7 MB)
  • 313 Views
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Article
Functionalization-dependent effects of cellulose nanofibrils on tolerogenic mechanisms of human dendritic cells
Sergej Tomić, Nataša Ilić, Vanja Kokol, Alisa Gruden-Movsesijan, Dušan Mihajlović, Marina Bekić, Ljiljana Sofronić-Milosavljević, Miodrag Čolić & Dragana Vučević
Pages: 6941-6960
Published online: 31 Oct 2018
AbstractforFunctionalization-dependent effects of cellulose nanofibrils on tolerogenic mechanisms of human dendritic cells | Full Text | References | PDF (14.2 MB)
  • 89 Views
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Article
Doxorubicin-loaded protease-activated near-infrared fluorescent polymeric nanoparticles for imaging and therapy of cancer
Tugba Yildiz, Renpeng Gu, Stefan Zauscher & Tania Betancourt
Pages: 6961-6986
Published online: 31 Oct 2018
AbstractforDoxorubicin-loaded protease-activated near-infrared fluorescent polymeric nanoparticles for imaging and therapy of cancer | Full Text | References | PDF (6.9 MB)
  • 138 Views
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Article
Biosafety evaluation of Janus Fe3O4-TiO2 nanoparticles in Sprague Dawley rats after intravenous injection
Hong Su, Xin Song, Juan Li, Muhammad Zubair Iqbal, Samuel Selorm Fiati Kenston, Zhen Li, Aiguo Wu, Min Ding & Jinshun Zhao
Pages: 6987-7001
Published online: 31 Oct 2018
AbstractforBiosafety evaluation of Janus Fe3O4-TiO2 nanoparticles in Sprague Dawley rats after intravenous injection | Full Text | References | PDF (20.3 MB)
  • 74 Views
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Article
Macroporous nanofibrous vascular scaffold with improved biodegradability and smooth muscle cells infiltration prepared by dual phase separation technique
Weizhong Wang, Wei Nie, Dinghua Liu, Haibo Du, Xiaojun Zhou, Liang Chen, Hongsheng Wang, Xiumei Mo, Lei Li & Chuanglong He
Pages: 7003-7018
Published online: 01 Nov 2018
AbstractforMacroporous nanofibrous vascular scaffold with improved biodegradability and smooth muscle cells infiltration prepared by dual phase separation technique | Full Text | References | PDF (15.9 MB)
  • 91 Views
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Article
Injectable hydrogel composite containing modified gold nanoparticles: implication in bone tissue regeneration
Donghyun Lee, Dong Nyoung Heo, Ha Ram Nah, Sang Jin Lee, Wan-Kyu Ko, Jae Seo Lee, Ho-Jin Moon, Jae Beum Bang, Yu-Shik Hwang, Rui L Reis & Il Keun Kwon
Pages: 7019-7031
Published online: 01 Nov 2018
AbstractforInjectable hydrogel composite containing modified gold nanoparticles: implication in bone tissue regeneration | Full Text | References | PDF (3.1 MB)
  • 223 Views
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Article
Inverse opal substrate-loaded mesenchymal stem cells contribute to decreased myocardial remodeling after transplantation into acute myocardial infarction mice
Wenbin Lu, JingJing Ji, Genshan Ma, Qiming Dai, Lijuan Chen, Pengfei Zuo & Yuanjin Zhao
Pages: 7033-7046
Published online: 28 Feb 2023
AbstractforInverse opal substrate-loaded mesenchymal stem cells contribute to decreased myocardial remodeling after transplantation into acute myocardial infarction mice | Full Text | References | PDF (5.2 MB)
  • 46 Views
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Article
Synthesis of gold nanoparticles with Solanum xanthocarpum extract and their in vitro anticancer potential on nasopharyngeal carcinoma cells
Pengfei Zhang, Peicheng Wang, Lei Yan & Lifeng Liu
Pages: 7047-7059
Published online: 01 Nov 2018
AbstractforSynthesis of gold nanoparticles with Solanum xanthocarpum extract and their in vitro anticancer potential on nasopharyngeal carcinoma cells | Full Text | References | PDF (3.1 MB)
  • 190 Views
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Article
Pulmonary impact of titanium dioxide nanorods: examination of nanorod-exposed rat lungs and human alveolar cells
Tamara Horváth, András Papp, Nóra Igaz, Dávid Kovács, Gábor Kozma, Vivien Trenka, László Tiszlavicz, Zsolt Rázga, Zoltán Kónya, Mónika Kiricsi & Tünde Vezér
Pages: 7061-7077
Published online: 02 Nov 2018
AbstractforPulmonary impact of titanium dioxide nanorods: examination of nanorod-exposed rat lungs and human alveolar cells | Full Text | References | PDF (7 MB)
  • 67 Views
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Article
Stearyl polyethylenimine complexed with plasmids as the core of human serum albumin nanoparticles noncovalently bound to CRISPR/Cas9 plasmids or siRNA for disrupting or silencing PD-L1 expression for immunotherapy
Wei-Jie Cheng, Ling-Chun Chen, Hsiu-O Ho, Hong-Liang Lin & Ming-Thau Sheu
Pages: 7079-7094
Published online: 02 Nov 2018
AbstractforStearyl polyethylenimine complexed with plasmids as the core of human serum albumin nanoparticles noncovalently bound to CRISPR/Cas9 plasmids or siRNA for disrupting or silencing PD-L1 expression for immunotherapy | Full Text | References | PDF (8 MB)
  • 174 Views
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Article
Orlistat-loaded solid SNEDDS for the enhanced solubility, dissolution, and in vivo performance
Dae Hun Kim, Jae Yeol Kim, Rae Man Kim, Pooja Maharjan, Yu-Geun Ji, Dong-Jin Jang, Kyoung Ah Min, Tae-Sung Koo & Kwan Hyung Cho
Pages: 7095-7106
Published online: 05 Nov 2018
AbstractforOrlistat-loaded solid SNEDDS for the enhanced solubility, dissolution, and in vivo performance | Full Text | References | PDF (2 MB)
  • 220 Views
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Article
Cationic vesicles for efficient shRNA transfection in the MCF-7 breast cancer cell line
Pardis Mokhtary, Bita Javan, Mahrokh Sharbatkhari, Alireza Soltani & Vahid Erfani-Moghadam
Pages: 7107-7121
Published online: 06 Nov 2018
AbstractforCationic vesicles for efficient shRNA transfection in the MCF-7 breast cancer cell line | Full Text | References | PDF (4.5 MB)
  • 147 Views
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Article
Nitroxide-radicals–modified gold nanorods for in vivo CT/MRI-guided photothermal cancer therapy
Luyao Xia, Chao Zhang, Min Li, Kaiyu Wang, Yushan Wang, Peipei Xu & Yong Hu
Pages: 7123-7134
Published online: 06 Nov 2018
AbstractforNitroxide-radicals–modified gold nanorods for in vivo CT/MRI-guided photothermal cancer therapy | Full Text | References | PDF (3.1 MB)
  • 89 Views
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Article
A novel disulfide bond-mediated cleavable RGD-modified PAMAM nanocomplex containing nuclear localization signal HMGB1 for enhancing gene transfection efficiency
Ji Li, Yuting Han, Yue Lu, Baohui Song, Ming Zhao, Haiyang Hu & Dawei Chen
Pages: 7135-7153
Published online: 06 Nov 2018
AbstractforA novel disulfide bond-mediated cleavable RGD-modified PAMAM nanocomplex containing nuclear localization signal HMGB1 for enhancing gene transfection efficiency | Full Text | References | PDF (6 MB)
  • 77 Views
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Article
Synthesis and characterization of a polyurethane carrier used for a prolonged transmembrane transfer of a chili pepper extract
Livia-Cristina Borcan, Zoltan Dudas, Adel Len, Janos Fuzi, Florin Borcan & Mirela Cleopatra Tomescu
Pages: 7155-7166
Published online: 06 Nov 2018
AbstractforSynthesis and characterization of a polyurethane carrier used for a prolonged transmembrane transfer of a chili pepper extract | Full Text | References | PDF (4.3 MB)
  • 84 Views
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Article
Small molecules modified biomimetic gelatin/hydroxyapatite nanofibers constructing an ideal osteogenic microenvironment with significantly enhanced cranial bone formation
Daowei Li, Kai Zhang, Ce Shi, Lijun Liu, Guangxing Yan, Cangwei Liu, Yijun Zhou, Yue Hu, Hongchen Sun & Bai Yang
Pages: 7167-7181
Published online: 06 Nov 2018
AbstractforSmall molecules modified biomimetic gelatin/hydroxyapatite nanofibers constructing an ideal osteogenic microenvironment with significantly enhanced cranial bone formation | Full Text | References | PDF (10.8 MB)
  • 111 Views
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Article
Reinforcement of calcium phosphate cement using alkaline-treated silk fibroin
Muli Hu, Zhiwei He, Fengxuan Han, Chen Shi, Pinghui Zhou, Feng Ling, Xuesong Zhu, Huilin Yang & Bin Li
Pages: 7183-7193
Published online: 09 Nov 2018
AbstractforReinforcement of calcium phosphate cement using alkaline-treated silk fibroin | Full Text | References | PDF (4.9 MB)
  • 94 Views
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Article
Enhancement of wound healing by single-wall/multi-wall carbon nanotubes complexed with chitosan
Naim Kittana, Mohyeddin Assali, Hanood Abu-Rass, Susanne Lutz, Rama Hindawi, Lina Ghannam, Marah Zakarneh & Ahmad Mousa
Pages: 7195-7206
Published online: 08 Nov 2018
AbstractforEnhancement of wound healing by single-wall/multi-wall carbon nanotubes complexed with chitosan | Full Text | References | PDF (7.3 MB)
  • 136 Views
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Article
A Geant4-based Monte Carlo study of a benchtop multi-pinhole X-ray fluorescence computed tomography imaging
Luzhen Deng, Biao Wei, Peng He, Yi Zhang & Peng Feng
Pages: 7207-7216
Published online: 08 Nov 2018
AbstractforA Geant4-based Monte Carlo study of a benchtop multi-pinhole X-ray fluorescence computed tomography imaging | Full Text | References | PDF (3.1 MB)
  • 126 Views
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Article
Nanotopographic cues and stiffness control of tendon-derived stem cells from diverse conditions
Sun Jeong Kim, Philip D Tatman, Da-Hyun Song, Albert O Gee, Deok-Ho Kim & Sang Jun Kim
Pages: 7217-7227
Published online: 08 Nov 2018
AbstractforNanotopographic cues and stiffness control of tendon-derived stem cells from diverse conditions | Full Text | References | PDF (2.8 MB)
  • 57 Views
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Article
pH-triggered charge-reversal and redox-sensitive drug-release polymer micelles codeliver doxorubicin and triptolide for prostate tumor therapy
Chen Xu, Ri-jin Song, Pei Lu, Jian-chun Chen, Yong-qiang Zhou, Gang Shen, Min-jun Jiang & Wei Zhang
Pages: 7229-7249
Published online: 08 Nov 2018
AbstractforpH-triggered charge-reversal and redox-sensitive drug-release polymer micelles codeliver doxorubicin and triptolide for prostate tumor therapy | Full Text | References | PDF (5.4 MB)
  • 176 Views
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Article
Gelatin–epigallocatechin gallate nanoparticles with hyaluronic acid decoration as eye drops can treat rabbit dry-eye syndrome effectively via inflammatory relief
Hsin-Yi Huang, Ming-Chen Wang, Zhi-Yu Chen, Wen-Ying Chiu, Ko-Hua Chen, I-Chan Lin, Wei-Chung Vivian Yang, Chi-Chang Wu & Ching-Li Tseng
Pages: 7251-7273
Published online: 08 Nov 2018
AbstractforGelatin–epigallocatechin gallate nanoparticles with hyaluronic acid decoration as eye drops can treat rabbit dry-eye syndrome effectively via inflammatory relief | Full Text | References | PDF (6 MB)
  • 255 Views
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Article
A Tf-modified tripterine-loaded coix seed oil microemulsion enhances anti-cervical cancer treatment
Yunyan Chen, Ding Qu, Rongping Fu, Mengfei Guo, Yue Qin, Jian Guo & Yan Chen
Pages: 7275-7287
Published online: 08 Nov 2018
AbstractforA Tf-modified tripterine-loaded coix seed oil microemulsion enhances anti-cervical cancer treatment | Full Text | References | PDF (2 MB)
  • 89 Views
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Article
Cetuximab-modified CuS nanoparticles integrating near-infrared-II-responsive photothermal therapy and anti-vessel treatment
Bin Li, Zhongyin Jiang, Diya Xie, Yiqing Wang & Xingzhen Lao
Pages: 7289-7302
Published online: 28 Feb 2023
AbstractforCetuximab-modified CuS nanoparticles integrating near-infrared-II-responsive photothermal therapy and anti-vessel treatment | Full Text | References | PDF (7.1 MB)
  • 128 Views
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Article
Silica nanoparticles trigger hepatic lipid-metabolism disorder in vivo and in vitro
Junchao Duan, Shuang Liang, Lin Feng, Yang Yu & Zhiwei Sun
Pages: 7303-7318
Published online: 09 Nov 2018
AbstractforSilica nanoparticles trigger hepatic lipid-metabolism disorder in vivo and in vitro | Full Text | References | PDF (5 MB)
  • 136 Views
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Article
Mechanisms of deformable nanovesicles based on insulin-phospholipid complex for enhancing buccal delivery of insulin
You Xu, Xing Zhang, Yun Zhang, Jun Ye, Hong-Liang Wang, Xuejun Xia & Yuling Liu
Pages: 7319-7331
Published online: 09 Nov 2018
AbstractforMechanisms of deformable nanovesicles based on insulin-phospholipid complex for enhancing buccal delivery of insulin | Full Text | References | PDF (10.9 MB)
  • 112 Views
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Review

Review Article
A review on nanosystems as an effective approach against infections of Staphylococcus aureus
Kaixiang Zhou, Chao Li, Dongmei Chen, Yuanhu Pan, Yanfei Tao, Wei Qu, Zhenli Liu, Xiaofang Wang & Shuyu Xie
Pages: 7333-7347
Published online: 09 Nov 2018
AbstractforA review on nanosystems as an effective approach against infections of Staphylococcus aureus | Full Text | References | PDF (2.5 MB)
  • 271 Views
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Review Article
Nanotechnology, an alternative with promising prospects and advantages for the treatment of cardiovascular diseases
Tao Li, Weitao Liang, Xijun Xiao & Yongjun Qian
Pages: 7349-7362
Published online: 09 Nov 2018
AbstractforNanotechnology, an alternative with promising prospects and advantages for the treatment of cardiovascular diseases | Full Text | References | PDF (378.3 KB)
  • 482 Views
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Original Research

Article
Curcumin nanoemulsion as a novel chemical for the treatment of acute and chronic toxoplasmosis in mice
Sanaz Jafarpour Azami, Aref Teimouri, Hossein Keshavarz, Amir Amani, Fariba Esmaeili, Hamid Hasanpour, Samira Elikaee, Hamid Salehiniya & Saeedeh Shojaee
Pages: 7363-7374
Published online: 09 Nov 2018
AbstractforCurcumin nanoemulsion as a novel chemical for the treatment of acute and chronic toxoplasmosis in mice | Full Text | References | PDF (1.7 MB)
  • 221 Views
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Article
Aerosol-synthesized siliceous nanoparticles: impact of morphology and functionalization on biodistribution
Philipp Diebolder, Miguel Vazquez-Pufleau, Nilantha Bandara, Cedric Mpoy, Ramesh Raliya, Elijah Thimsen, Pratim Biswas & Buck E Rogers
Pages: 7375-7393
Published online: 28 Feb 2023
AbstractforAerosol-synthesized siliceous nanoparticles: impact of morphology and functionalization on biodistribution | Full Text | References | PDF (1.6 MB)
  • 64 Views
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Article
Nanoparticle-modified chitosan-agarose-gelatin scaffold for sustained release of SDF-1 and BMP-2
Bin Wang, Yuanwei Guo, Xiaofeng Chen, Chao Zeng, Qikang Hu, Wei Yin, Wei Li, Hui Xie, Bingyu Zhang, Xingchun Huang & Fenglei Yu
Pages: 7395-7408
Published online: 12 Nov 2018
AbstractforNanoparticle-modified chitosan-agarose-gelatin scaffold for sustained release of SDF-1 and BMP-2 | Full Text | References | PDF (10.1 MB)
  • 253 Views
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Article
Peritumoral implantation of hydrogel-containing nanoparticles and losartan for enhanced nanoparticle penetration and antitumor effect
Haijun Shen, Qianqian Gao, Qi Ye, Shiyun Yang, Yuqian Wu, Qin Huang, Xiaona Wang & Zhenhua Sun
Pages: 7409-7426
Published online: 13 Nov 2018
AbstractforPeritumoral implantation of hydrogel-containing nanoparticles and losartan for enhanced nanoparticle penetration and antitumor effect | Full Text | References | PDF (9.6 MB)
  • 134 Views
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Article
A niosome formulation modulates the Th1/Th2 bias immune response in mice and also provides protection against anthrax spore challenge
Himanshu Gogoi, Rajesh Mani & Rakesh Bhatnagar
Pages: 7427-7440
Published online: 14 Nov 2018
AbstractforA niosome formulation modulates the Th1/Th2 bias immune response in mice and also provides protection against anthrax spore challenge | Full Text | References | PDF (3.1 MB)
  • 73 Views
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Article
Regulation of in vivo behavior of TAT-modified liposome by associated protein corona and avidity to tumor cells
Mohamadreza Amin, Mahsa Bagheri, Mercedeh Mansourian, Mahmoud Reza Jaafari & Timo LM ten Hagen
Pages: 7441-7455
Published online: 15 Nov 2018
AbstractforRegulation of in vivo behavior of TAT-modified liposome by associated protein corona and avidity to tumor cells | Full Text | References | PDF (3.6 MB)
  • 101 Views
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Article
Redox-responsive hyaluronic acid-functionalized graphene oxide nanosheets for targeted delivery of water-insoluble cancer drugs
Jian Liu, Doudou Zhang, Shu Lian, Junxia Zheng, Bifei Li, Tao Li & Lee Jia
Pages: 7457-7472
Published online: 14 Nov 2018
AbstractforRedox-responsive hyaluronic acid-functionalized graphene oxide nanosheets for targeted delivery of water-insoluble cancer drugs | Full Text | References | PDF (3.9 MB)
  • 94 Views
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Review

Review Article
Selenium as a pleiotropic agent for medical discovery and drug delivery
Baozhang Guan, Ruiling Yan, Ruiman Li & Xingwang Zhang
Pages: 7473-7490
Published online: 28 Feb 2023
AbstractforSelenium as a pleiotropic agent for medical discovery and drug delivery | Full Text | References | PDF (5.5 MB)
  • 316 Views
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Original Research

Article
Controlled and sustained drug release performance of calcium sulfate cement porous TiO2 microsphere composites
Wei Luo, Zhen Geng, Zhaoyang Li, Shuilin Wu, Zhenduo Cui, Shengli Zhu, Yanqin Liang & Xianjin Yang
Pages: 7491-7501
Published online: 14 Nov 2018
AbstractforControlled and sustained drug release performance of calcium sulfate cement porous TiO2 microsphere composites | Full Text | References | PDF (8.5 MB)
  • 64 Views
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Article
Biomimetic intrafibrillar mineralized collagen promotes bone regeneration via activation of the Wnt signaling pathway
Zhen Zhang, Zheyi Li, Chengyao Zhang, Jiannan Liu, Yuxing Bai, Song Li & Chenping Zhang
Pages: 7503-7516
Published online: 21 Nov 2018
AbstractforBiomimetic intrafibrillar mineralized collagen promotes bone regeneration via activation of the Wnt signaling pathway | Full Text | References | PDF (5.3 MB)
  • 71 Views
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Article
A666-conjugated nanoparticles target prestin of outer hair cells preventing cisplatin-induced hearing loss
Xueling Wang, Yuming Chen, Yong Tao, Yunge Gao, Dehong Yu & Hao Wu
Pages: 7517-7531
Published online: 14 Nov 2018
AbstractforA666-conjugated nanoparticles target prestin of outer hair cells preventing cisplatin-induced hearing loss | Full Text | References | PDF (5 MB)
  • 84 Views
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Study Protocol

Article
Bufalin-loaded vitamin E succinate-grafted-chitosan oligosaccharide/RGD conjugated TPGS mixed micelles demonstrated improved antitumor activity against drug-resistant colon cancer
Zeting Yuan, Yuxia Yuan, Lin Han, Yanyan Qiu, Xiaqin Huang, Feng Gao, Guohua Fan, Yixi Zhang, Xueyao Tang, Xue He, Ke Xu & Peihao Yin
Pages: 7533-7548
Published online: 28 Feb 2023
AbstractforBufalin-loaded vitamin E succinate-grafted-chitosan oligosaccharide/RGD conjugated TPGS mixed micelles demonstrated improved antitumor activity against drug-resistant colon cancer | Full Text | References | PDF (5.1 MB)
  • 93 Views
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Original Research

Article
Enhanced anticancer activity and intracellular uptake of paclitaxel-containing solid lipid nanoparticles in multidrug-resistant breast cancer cells
Wenting Xu, Eun Ju Bae & Mi-Kyung Lee
Pages: 7549-7563
Published online: 15 Nov 2018
AbstractforEnhanced anticancer activity and intracellular uptake of paclitaxel-containing solid lipid nanoparticles in multidrug-resistant breast cancer cells | Full Text | References | PDF (4.1 MB)
  • 176 Views
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Article
Reverse micelle-lipid nanocapsules: a novel strategy for drug delivery of the plectasin derivate AP138 antimicrobial peptide
Anne-Claire Groo, Nada Matougui, Anita Umerska & Patrick Saulnier
Pages: 7565-7574
Published online: 15 Nov 2018
AbstractforReverse micelle-lipid nanocapsules: a novel strategy for drug delivery of the plectasin derivate AP138 antimicrobial peptide | Full Text | References | PDF (830.8 KB)
  • 143 Views
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Review

Review Article
Nanodelivery systems and stabilized solid-drug nanoparticles for orally administered medicine: current landscape
Ali Kermanizadeh, Leagh G Powell, Vicki Stone & Peter Møller
Pages: 7575-7605
Published online: 16 Nov 2018
AbstractforNanodelivery systems and stabilized solid-drug nanoparticles for orally administered medicine: current landscape | Full Text | References | PDF (606.7 KB)
  • 159 Views
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Original Research

Article
Fabricating polydopamine-coated MoSe2-wrapped hollow mesoporous silica nanoplatform for controlled drug release and chemo-photothermal therapy
Song Chai, Shifeng Kan, Ran Sun, Ruijuan Zhou, Yi Sun, Wenhua Chen & Bo Yu
Pages: 7607-7621
Published online: 28 Feb 2023
AbstractforFabricating polydopamine-coated MoSe2-wrapped hollow mesoporous silica nanoplatform for controlled drug release and chemo-photothermal therapy | Full Text | References | PDF (10.9 MB)
  • 204 Views
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Article
Enhanced photo/chemo combination efficiency against bladder tumor by encapsulation of DOX and ZnPC into in situ-formed thermosensitive polymer hydrogel
Zhongming Huang, He Xiao, Xiangyun Lu, Weigang Yan & Zhigang Ji
Pages: 7623-7631
Published online: 28 Feb 2023
AbstractforEnhanced photo/chemo combination efficiency against bladder tumor by encapsulation of DOX and ZnPC into in situ-formed thermosensitive polymer hydrogel | Full Text | References | PDF (1.4 MB)
  • 106 Views
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Article
Tailor-made PL-UC-C3 nanoparticles for fluorescence/computed tomography imaging-guided cascade amplified photothermal therapy
Xinhui Xie, Jialei Song, Yili Hu, Suyang Zhuang, Yuntao Wang, Yunlei Zhao & Qian Lu
Pages: 7633-7646
Published online: 19 Nov 2018
AbstractforTailor-made PL-UC-C3 nanoparticles for fluorescence/computed tomography imaging-guided cascade amplified photothermal therapy | Full Text | References | PDF (15.7 MB)
  • 62 Views
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Article
Folate receptor targeting of radiolabeled liposomes reduces intratumoral liposome accumulation in human KB carcinoma xenografts
Esben Christensen, Jonas R Henriksen, Jesper T Jørgensen, Yasmine Amitay, Hilary Shmeeda, Alberto A Gabizon, Andreas Kjær, Thomas L Andresen & Anders E Hansen
Pages: 7647-7656
Published online: 19 Nov 2018
AbstractforFolate receptor targeting of radiolabeled liposomes reduces intratumoral liposome accumulation in human KB carcinoma xenografts | Full Text | References | PDF (4.4 MB)
  • 53 Views
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Article
Initial osteoblast adhesion and subsequent differentiation on zirconia surfaces are regulated by integrins and heparin-sensitive molecule
Feng Luo, Guang Hong, Hiroyuki Matsui, Kosei Endo, Qianbing Wan & Keiichi Sasaki
Pages: 7657-7667
Published online: 19 Nov 2018
AbstractforInitial osteoblast adhesion and subsequent differentiation on zirconia surfaces are regulated by integrins and heparin-sensitive molecule | Full Text | References | PDF (9 MB)
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Article
Decapeptide functionalized targeted mesoporous silica nanoparticles with doxorubicin exhibit enhanced apoptotic effect in breast and prostate cancer cells
Prajakta Tambe, Pramod Kumar, Kishore M Paknikar & Virendra Gajbhiye
Pages: 7669-7680
Published online: 19 Nov 2018
AbstractforDecapeptide functionalized targeted mesoporous silica nanoparticles with doxorubicin exhibit enhanced apoptotic effect in breast and prostate cancer cells | Full Text | References | PDF (3.3 MB)
  • 151 Views
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Article
Novel pH-sensitive zinc phthalocyanine assembled with albumin for tumor targeting and treatment
Ying Wang, Ke Zheng, Guangshan Xuan, Mingdong Huang & Jinping Xue
Pages: 7681-7695
Published online: 28 Feb 2023
AbstractforNovel pH-sensitive zinc phthalocyanine assembled with albumin for tumor targeting and treatment | Full Text | References | PDF (3 MB)
  • 92 Views
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Article
Redox/pH dual-controlled release of chlorhexidine and silver ions from biodegradable mesoporous silica nanoparticles against oral biofilms
Meng-meng Lu, Yuran Ge, Jing Qiu, Dan Shao, Yue Zhang, Jing Bai, Xiao Zheng, Zhi-min Chang, Zheng Wang, Wen-fei Dong & Chun-bo Tang
Pages: 7697-7709
Published online: 19 Nov 2018
AbstractforRedox/pH dual-controlled release of chlorhexidine and silver ions from biodegradable mesoporous silica nanoparticles against oral biofilms | Full Text | References | PDF (9.8 MB)
  • 195 Views
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Article
Lipid surface modifications increase mesoporous silica nanoparticle labeling properties in mesenchymal stem cells
Roger Rosenbrand, David Barata, Pichaporn Sutthavas, Ronny Mohren, Berta Cillero-Pastor, Pamela Habibovic & Sabine van Rijt
Pages: 7711-7725
Published online: 20 Nov 2018
AbstractforLipid surface modifications increase mesoporous silica nanoparticle labeling properties in mesenchymal stem cells | Full Text | References | PDF (2.5 MB)
  • 89 Views
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Article
Exosome-mediated delivery of functionally active miRNA-142-3p inhibitor reduces tumorigenicity of breast cancer in vitro and in vivo
Zahra Naseri, Reza Kazemi Oskuee, Mahmoud Reza Jaafari & Mehdi Forouzandeh Moghadam
Pages: 7727-7747
Published online: 20 Nov 2018
AbstractforExosome-mediated delivery of functionally active miRNA-142-3p inhibitor reduces tumorigenicity of breast cancer in vitro and in vivo | Full Text | References | PDF (7.9 MB)
  • 536 Views
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Review

Review Article
Recent advances in ultrasound-based transdermal drug delivery
Brenden Cheong-Qi Seah & Boon Mian Teo
Pages: 7749-7763
Published online: 20 Nov 2018
AbstractforRecent advances in ultrasound-based transdermal drug delivery | Full Text | References | PDF (5.1 MB)
  • 684 Views
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Original Research

Article
Effects of quercetin and arginine on the nephrotoxicity and lipid peroxidation induced by gold nanoparticles in vivo
Mohamed Anwar K Abdelhalim, Huda AY Qaid, Yanallah Al-Mohy & Mohammed Suliman Al-Ayed
Pages: 7765-7770
Published online: 21 Nov 2018
AbstractforEffects of quercetin and arginine on the nephrotoxicity and lipid peroxidation induced by gold nanoparticles in vivo | Full Text | References | PDF (533.8 KB)
  • 86 Views
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Article
Nitric oxide-releasing nanoparticles improve doxorubicin anticancer activity
Houman Alimoradi, Khaled Greish, Anita Barzegar-Fallah, Lama Alshaibani & Valeria Pittalà
Pages: 7771-7787
Published online: 20 Nov 2018
AbstractforNitric oxide-releasing nanoparticles improve doxorubicin anticancer activity | Full Text | References | PDF (4.1 MB)
  • 131 Views
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Article
Biogenic pentagonal silver nanoparticles for safer and more effective antibacterial therapeutics
Salman Khan, Khurshid Ahmad, Ajaz Ahmad, Mohammad Raish, Basit L Jan, Altaf Khan & Mohd Sajid Khan
Pages: 7789-7799
Published online: 21 Nov 2018
AbstractforBiogenic pentagonal silver nanoparticles for safer and more effective antibacterial therapeutics | Full Text | References | PDF (2.9 MB)
  • 125 Views
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Article
A 89Zr-labeled lipoplex nanosystem for image-guided gene delivery: design, evaluation of stability and in vivo behavior
Istvan Hajdu, Amal Makhlouf, Viswas Raja Solomon, Deborah Michel, Mays Al-Dulaymi, Kishor M Wasan, Humphrey Fonge & Ildiko Badea
Pages: 7801-7818
Published online: 21 Nov 2018
AbstractforA 89Zr-labeled lipoplex nanosystem for image-guided gene delivery: design, evaluation of stability and in vivo behavior | Full Text | References | PDF (3.2 MB)
  • 70 Views
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Article
Co-exposure subacute toxicity of silica nanoparticles and lead acetate on cardiovascular system
Lin Feng, Xiaozhe Yang, Yanfeng Shi, Shuang Liang, Tong Zhao, Junchao Duan & Zhiwei Sun
Pages: 7819-7834
Published online: 21 Nov 2018
AbstractforCo-exposure subacute toxicity of silica nanoparticles and lead acetate on cardiovascular system | Full Text | References | PDF (9.5 MB)
  • 144 Views
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Article
Dimethyl 2,2′-[2,2′-(ethane-1,1-diyl)bis(1H-indole-3,2-diyl)]-diacetate: a small molecule capable of nano-scale assembly, inhibiting venous thrombosis and inducing no bleeding side effect
Yaonan Wang, Haiyan Chen, Xiaoyi Zhang, Lin Gui, Jianhui Wu, Qiqi Feng, Shiqi Peng & Ming Zhao
Pages: 7835-7844
Published online: 22 Nov 2018
AbstractforDimethyl 2,2′-[2,2′-(ethane-1,1-diyl)bis(1H-indole-3,2-diyl)]-diacetate: a small molecule capable of nano-scale assembly, inhibiting venous thrombosis and inducing no bleeding side effect | Full Text | References | PDF (5.1 MB)
  • 46 Views
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Article
Mechanism research on a bioactive resveratrol– PLA–gelatin porous nano-scaffold in promoting the repair of cartilage defect
Fei Yu, Ming Li, Zhipeng Yuan, Feng Rao, Xingxing Fang, Baoguo Jiang, Yongqiang Wen & Peixun Zhang
Pages: 7845-7858
Published online: 22 Nov 2018
AbstractforMechanism research on a bioactive resveratrol– PLA–gelatin porous nano-scaffold in promoting the repair of cartilage defect | Full Text | References | PDF (2.6 MB)
  • 149 Views
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Article
Targeted delivery of reduced graphene oxide nanosheets using multifunctional ultrasound nanobubbles for visualization and enhanced photothermal therapy
Zhao Liu, Jia Zhang, Yuhang Tian, Lei Zhang, Xue Han, Qiucheng Wang & Wen Cheng
Pages: 7859-7872
Published online: 22 Nov 2018
AbstractforTargeted delivery of reduced graphene oxide nanosheets using multifunctional ultrasound nanobubbles for visualization and enhanced photothermal therapy | Full Text | References | PDF (6.8 MB)
  • 96 Views
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Article
Fabrication and evaluation of a γ-PGA-based self-assembly transferrin receptor-targeting anticancer drug carrier
Li Zhang, Xiaoyu Zhu, Shijia Wu, Yazhou Chen, Shiming Tan, Yingjie Liu, Wenzheng Jiang & Jing Huang
Pages: 7873-7889
Published online: 22 Nov 2018
AbstractforFabrication and evaluation of a γ-PGA-based self-assembly transferrin receptor-targeting anticancer drug carrier | Full Text | References | PDF (4.4 MB)
  • 73 Views
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Article
Electrospun nanofiber blend with improved mechanical and biological performance
Anderson Oliveira Lobo, Samson Afewerki, Mirian Michele Machado de Paula, Paria Ghannadian, Fernanda Roberta Marciano, Yu Shrike Zhang, Thomas Jay Webster & Ali Khademhosseini
Pages: 7891-7903
Published online: 22 Nov 2018
AbstractforElectrospun nanofiber blend with improved mechanical and biological performance | Full Text | References | PDF (8.2 MB)
  • 299 Views
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Article
Macrophage uptake switches on OCT contrast of superparamagnetic nanoparticles for imaging of atherosclerotic plaques
Angela Ariza de Schellenberger, Wolfram C Poller, Verena Stangl, Ulf Landmesser & Eyk Schellenberger
Pages: 7905-7913
Published online: 23 Nov 2018
AbstractforMacrophage uptake switches on OCT contrast of superparamagnetic nanoparticles for imaging of atherosclerotic plaques | Full Text | References | PDF (2.7 MB)
  • 66 Views
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Review

Review Article
Vascular targeted nanotherapeutic approach for obesity treatment
Nicole Remaliah Samantha Sibuyi, Mervin Meyer, Martin Opiyo Onani, Amanda Skepu & Abram Madimabe Madiehe
Pages: 7915-7929
Published online: 23 Nov 2018
AbstractforVascular targeted nanotherapeutic approach for obesity treatment | Full Text | References | PDF (1.2 MB)
  • 166 Views
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Original Research

Article
Potential effects of different natural antioxidants on inflammatory damage and oxidative-mediated hepatotoxicity induced by gold nanoparticles
Mohamed Anwar K Abdelhalim, Sherif A Abdelmottaleb Moussa, Huda AY Qaid & Mohammed Suliman Al-Ayed
Pages: 7931-7938
Published online: 23 Nov 2018
AbstractforPotential effects of different natural antioxidants on inflammatory damage and oxidative-mediated hepatotoxicity induced by gold nanoparticles | Full Text | References | PDF (926.1 KB)
  • 124 Views
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Article
Silica–gentamicin nanohybrids: combating antibiotic resistance, bacterial biofilms, and in vivo toxicity
Dina A Mosselhy, Wei He, Ulla Hynönen, Yaping Meng, Pezhman Mohammadi, Airi Palva, Qingling Feng, Simo-Pekka Hannula, Katrina Nordström & Markus B Linder
Pages: 7939-7957
Published online: 28 Nov 2018
AbstractforSilica–gentamicin nanohybrids: combating antibiotic resistance, bacterial biofilms, and in vivo toxicity | Full Text | References | PDF (8.3 MB)
  • 94 Views
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Review

Review Article
Novel application of trimethyl chitosan as an adjuvant in vaccine delivery
Anshu Malik, Manish Gupta, Vatika Gupta, Himanshu Gogoi & Rakesh Bhatnagar
Pages: 7959-7970
Published online: 23 Nov 2018
AbstractforNovel application of trimethyl chitosan as an adjuvant in vaccine delivery | Full Text | References | PDF (2.2 MB)
  • 174 Views
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Original Research

Article
Safe decontamination of cytostatics from the nitrogen mustards family. Part one: cyclophosphamide and ifosfamide
Irena R Štenglová Netíková, Luboš Petruželka, Martin Šťastný & Václav Štengl
Pages: 7971-7985
Published online: 26 Nov 2018
AbstractforSafe decontamination of cytostatics from the nitrogen mustards family. Part one: cyclophosphamide and ifosfamide | Full Text | References | PDF (3.4 MB)
  • 55 Views
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Article
Sub-10 nm Cu5FeS4 cube for magnetic resonance imaging-guided photothermal therapy of cancer
Dan Wang, Yuwen Zhang & Qi Guo
Pages: 7987-7996
Published online: 26 Nov 2018
AbstractforSub-10 nm Cu5FeS4 cube for magnetic resonance imaging-guided photothermal therapy of cancer | Full Text | References | PDF (3.6 MB)
  • 74 Views
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Article
Apically targeted oral micelles exhibit highly efficient intestinal uptake and oral absorption
Jinling Wang, Lifang Wang, Ying Li, Xiaohui Wang & Pengfei Tu
Pages: 7997-8012
Published online: 26 Nov 2018
AbstractforApically targeted oral micelles exhibit highly efficient intestinal uptake and oral absorption | Full Text | References | PDF (5.3 MB)
  • 106 Views
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Article
Selective cytotoxicity of green synthesized silver nanoparticles against the MCF-7 tumor cell line and their enhanced antioxidant and antimicrobial properties
Sadegh Khorrami, Ali Zarrabi, Moj Khaleghi, Marziyeh Danaei & MR Mozafari
Pages: 8013-8024
Published online: 27 Nov 2018
AbstractforSelective cytotoxicity of green synthesized silver nanoparticles against the MCF-7 tumor cell line and their enhanced antioxidant and antimicrobial properties | Full Text | References | PDF (3.3 MB)
  • 773 Views
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Article
Synergistic photoactivated antimicrobial effects of carbon dots combined with dye photosensitizers
Xiuli Dong, Ambrose E Bond, Nengyu Pan, Montrez Coleman, Yongan Tang, Ya-Ping Sun & Liju Yang
Pages: 8025-8035
Published online: 27 Nov 2018
AbstractforSynergistic photoactivated antimicrobial effects of carbon dots combined with dye photosensitizers | Full Text | References | PDF (882.9 KB)
  • 165 Views
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Article
A comparative study of toxicity of TiO2, ZnO, and Ag nanoparticles to human aortic smooth-muscle cells
Maolin Wang, Qianyu Yang, Jimin Long, Yanghuai Ding, Xiaoqing Zou, Guochao Liao & Yi Cao
Pages: 8037-8049
Published online: 27 Nov 2018
AbstractforA comparative study of toxicity of TiO2, ZnO, and Ag nanoparticles to human aortic smooth-muscle cells | Full Text | References | PDF (6.3 MB)
  • 81 Views
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Article
Chemiplasmonics for high-throughput biosensors
Achyut J Raghavendra, Jingyi Zhu, Wren Gregory, Fengjiao Case, Pradyumna Mulpur, Shahzad Khan, Anurag Srivastava & Ramakrishna Podila
Pages: 8051-8062
Published online: 27 Nov 2018
AbstractforChemiplasmonics for high-throughput biosensors | Full Text | References | PDF (5.8 MB)
  • 56 Views
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Article
Intraperitoneal delivery of NanoOlaparib for disseminated late-stage cancer treatment
Paige Baldwin, Anders W Ohman, Shifalika Tangutoori, Daniela M Dinulescu & Srinivas Sridhar
Pages: 8063-8074
Published online: 29 Nov 2018
AbstractforIntraperitoneal delivery of NanoOlaparib for disseminated late-stage cancer treatment | Full Text | References | PDF (2.7 MB)
  • 87 Views
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Article
A TEM-traceable physiologically functional gold nanoprobe that permeates non-endocytic cells
Maria Victoria Berberian, Cristian A Pocognoni & Luis S Mayorga
Pages: 8075-8086
Published online: 28 Nov 2018
AbstractforA TEM-traceable physiologically functional gold nanoprobe that permeates non-endocytic cells | Full Text | References | PDF (4.9 MB)
  • 44 Views
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Article
Novel BUF2-magnetite nanobioconjugates with cell-penetrating abilities
Monica Cuellar, Javier Cifuentes, Jessica Perez, Alejandra Suarez-Arnedo, Julian A Serna, Helena Groot, Carolina Muñoz-Camargo & Juan C Cruz
Pages: 8087-8094
Published online: 28 Nov 2018
AbstractforNovel BUF2-magnetite nanobioconjugates with cell-penetrating abilities | Full Text | References | PDF (1.1 MB)
  • 149 Views
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Article
Exosome-encapsulated antibiotic against intracellular infections of methicillin-resistant Staphylococcus aureus
Xiaohong Yang, Gongming Shi, Jian Guo, Chenhui Wang & Yun He
Pages: 8095-8104
Published online: 29 Nov 2018
AbstractforExosome-encapsulated antibiotic against intracellular infections of methicillin-resistant Staphylococcus aureus | Full Text | References | PDF (1.5 MB)
  • 459 Views
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Article
Liposomal drug delivery in an in vitro 3D bone marrow model for multiple myeloma
Maaike VJ Braham, Anil K Deshantri, Monique C Minnema, F Cumhur Öner, Raymond M Schiffelers, Marcel HAM Fens & Jacqueline Alblas
Pages: 8105-8118
Published online: 29 Nov 2018
AbstractforLiposomal drug delivery in an in vitro 3D bone marrow model for multiple myeloma | Full Text | References | PDF (8.8 MB)
  • 164 Views
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Article
Functional chlorin gold nanorods enable to treat breast cancer by photothermal/photodynamic therapy
Lei Liu, Hong-Jun Xie, Li-Min Mu, Rui Liu, Zhan-Bo Su, Yi-Nuo Cui, Ying Xie & Wan-Liang Lu
Pages: 8119-8135
Published online: 29 Nov 2018
AbstractforFunctional chlorin gold nanorods enable to treat breast cancer by photothermal/photodynamic therapy | Full Text | References | PDF (5 MB)
  • 115 Views
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Article
Gold nanoparticles – an optical biosensor for RNA quantification for cancer and neurologic disorders diagnosis
Sherif M Shawky, Ahmed M Awad, Arwa A Abugable & Sherif F El-Khamisy
Pages: 8137-8151
Published online: 29 Nov 2018
AbstractforGold nanoparticles – an optical biosensor for RNA quantification for cancer and neurologic disorders diagnosis | Full Text | References | PDF (2.9 MB)
  • 126 Views
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Article
RETRACTED ARTICLE: Activation of polymeric nanoparticle intracellular targeting overcomes chemodrug resistance in human primary patient breast cancer cells
Amoura M Abou-El-Naga, Ghada Mutawa, Ibrahim M El-Sherbiny & Shaker A Mousa
Pages: 8153-8164
Published online: 29 Nov 2018
AbstractforRETRACTED ARTICLE: Activation of polymeric nanoparticle intracellular targeting overcomes chemodrug resistance in human primary patient breast cancer cells | PDF (2.4 MB)
  • 46 Views
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Article
The role of the ERK1/2 pathway in simvastatin-loaded nanomicelles and simvastatin in regulating the osteogenic effect in MG63 cells
Mao Niu, Xianling Feng & Lei Zhou
Pages: 8165-8178
Published online: 05 Dec 2018
AbstractforThe role of the ERK1/2 pathway in simvastatin-loaded nanomicelles and simvastatin in regulating the osteogenic effect in MG63 cells | Full Text | References | PDF (12 MB)
  • 40 Views
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Article
Polydopamine-induced hydroxyapatite coating facilitates hydroxyapatite/polyamide 66 implant osteogenesis: an in vitro and in vivo evaluation
Yanan Xu, Hong Li, Jieming Wu, Qiming Yang, Dianming Jiang & Bo Qiao
Pages: 8179-8193
Published online: 30 Nov 2018
AbstractforPolydopamine-induced hydroxyapatite coating facilitates hydroxyapatite/polyamide 66 implant osteogenesis: an in vitro and in vivo evaluation | Full Text | References | PDF (9.4 MB)
  • 157 Views
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Article
Surface engineered polyanhydride-based oral Salmonella subunit nanovaccine for poultry
Sankar Renu, Ashley D Markazi, Santosh Dhakal, Yashavanth S Lakshmanappa, Suren R Gourapura, Revathi Shanmugasundaram, Sujata Senapati, Balaji Narasimhan, Ramesh K Selvaraj & Gourapura J Renukaradhya
Pages: 8195-8215
Published online: 28 Feb 2023
AbstractforSurface engineered polyanhydride-based oral Salmonella subunit nanovaccine for poultry | Full Text | References | PDF (11.5 MB)
  • 179 Views
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Article
Enhancement of osteoblast activity on nanostructured NiTi/hydroxyapatite coatings on additive manufactured NiTi metal implants by nanosecond pulsed laser sintering
Biwei Deng, Angela Bruzzaniti & Gary J Cheng
Pages: 8217-8230
Published online: 30 Nov 2018
AbstractforEnhancement of osteoblast activity on nanostructured NiTi/hydroxyapatite coatings on additive manufactured NiTi metal implants by nanosecond pulsed laser sintering | Full Text | References | PDF (4.7 MB)
  • 90 Views
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Article
Encapsulation of chloroquine and doxorubicin by MPEG-PLA to enhance anticancer effects by lysosomes inhibition in ovarian cancer
Ming Shao, Weitao Zhu, Xianping Lv, Qiankun Yang, Xin Liu, Ying Xie, Ping Tang & Ling Sun
Pages: 8231-8245
Published online: 03 Dec 2018
AbstractforEncapsulation of chloroquine and doxorubicin by MPEG-PLA to enhance anticancer effects by lysosomes inhibition in ovarian cancer | Full Text | References | PDF (5.2 MB)
  • 138 Views
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Article
Highly stable RGD/disulfide bridge-bearing star-shaped biodegradable nanocarriers for enhancing drug-loading efficiency, rapid cellular uptake, and on-demand cargo release
Jianqin Yan, Hai Zhang, Furong Cheng, Yanmei He, Ting Su, Xuequan Zhang, Man Zhang, Yutong Zhu, Congrui Li, Jun Cao & Bin He
Pages: 8247-8268
Published online: 04 Dec 2018
AbstractforHighly stable RGD/disulfide bridge-bearing star-shaped biodegradable nanocarriers for enhancing drug-loading efficiency, rapid cellular uptake, and on-demand cargo release | Full Text | References | PDF (5.6 MB)
  • 76 Views
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Article
Bacterial magnetosomes-based nanocarriers for co-delivery of cancer therapeutics in vitro
Rui-Min Long, Qing-Lei Dai, Xia Zhou, Duan-Hua Cai, Ya-Zhen Hong, Shi-Bin Wang & Yuan-Gang Liu
Pages: 8269-8279
Published online: 04 Dec 2018
AbstractforBacterial magnetosomes-based nanocarriers for co-delivery of cancer therapeutics in vitro | Full Text | References | PDF (3.1 MB)
  • 81 Views
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Article
Stability, safety, and transcorneal mechanistic studies of ophthalmic lyophilized cyclosporine-loaded polymeric micelles
Yan Shen, Yinglan Yu, Birendra Chaurasiya, Xiaolian Li, Ying Xu, Thomas J Webster, Jiasheng Tu & Runing Sun
Pages: 8281-8296
Published online: 05 Dec 2018
AbstractforStability, safety, and transcorneal mechanistic studies of ophthalmic lyophilized cyclosporine-loaded polymeric micelles | Full Text | References | PDF (14.2 MB)
  • 110 Views
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Article
Surface nanocavitation of titanium modulates macrophage activity
Marianne B Ariganello, Dainelys Guadarrama Bello, Alejandra Rodriguez-Contreras, Shayan Sadeghi, Gaetano Isola, Fabio Variola & Antonio Nanci
Pages: 8297-8308
Published online: 05 Dec 2018
AbstractforSurface nanocavitation of titanium modulates macrophage activity | Full Text | References | PDF (15.3 MB)
  • 65 Views
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Article
Curcumin-loaded galactosylated BSA nanoparticles as targeted drug delivery carriers inhibit hepatocellular carcinoma cell proliferation and migration
Yike Huang, Lu Hu, Shan Huang, Wanjun Xu, Jingyuan Wan, Dandan Wang, Guocan Zheng & Zhining Xia
Pages: 8309-8323
Published online: 06 Dec 2018
AbstractforCurcumin-loaded galactosylated BSA nanoparticles as targeted drug delivery carriers inhibit hepatocellular carcinoma cell proliferation and migration | Full Text | References | PDF (9.2 MB)
  • 245 Views
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Review

Review Article
Nanotechnology-enabled materials for hemostatic and anti-infection treatments in orthopedic surgery
Haolin Sun, Lu Lv, Yanjie Bai, Huilin Yang, Huan Zhou, Chunde Li & Lei Yang
Pages: 8325-8338
Published online: 06 Dec 2018
AbstractforNanotechnology-enabled materials for hemostatic and anti-infection treatments in orthopedic surgery | Full Text | References | PDF (4.2 MB)
  • 212 Views
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Original Research

Article
Transferrin receptor-targeted HMSN for sorafenib delivery in refractory differentiated thyroid cancer therapy
You Ke & Cheng Xiang
Pages: 8339-8354
Published online: 28 Feb 2023
AbstractforTransferrin receptor-targeted HMSN for sorafenib delivery in refractory differentiated thyroid cancer therapy | Full Text | References | PDF (5.1 MB)
  • 96 Views
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Article
Extended pain relief achieved by analgesic-eluting biodegradable nanofibers in the Nuss procedure: in vitro and in vivo studies
Kuo-Sheng Liu, Wei-Hsun Chen, Cheng-Hung Lee, Yong-Fong Su & Shih-Jung Liu
Pages: 8355-8364
Published online: 07 Dec 2018
AbstractforExtended pain relief achieved by analgesic-eluting biodegradable nanofibers in the Nuss procedure: in vitro and in vivo studies | Full Text | References | PDF (3.9 MB)
  • 58 Views
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Article
A flow cytometric analysis of macrophage– nanoparticle interactions in vitro: induction of altered Toll-like receptor expression
Joyce M Njoroge, Jeffrey J Yourick & Mary Ann Principato
Pages: 8365-8378
Published online: 12 Dec 2018
AbstractforA flow cytometric analysis of macrophage– nanoparticle interactions in vitro: induction of altered Toll-like receptor expression | Full Text | References | PDF (2.5 MB)
  • 73 Views
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Article
A high bioavailability and sustained-release nano-delivery system for nintedanib based on electrospray technology
Hongfei Liu, Kunyu Du, Dongli Li, Yi Du, Jumei Xi, Ying Xu, Yan Shen, Tao Jiang & Thomas J Webster
Pages: 8379-8393
Published online: 10 Dec 2018
AbstractforA high bioavailability and sustained-release nano-delivery system for nintedanib based on electrospray technology | Full Text | References | PDF (14 MB)
  • 425 Views
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Article
Mixing lipids to manipulate the ionization status of lipid nanoparticles for specific tissue targeting
Nour Shobaki, Yusuke Sato & Hideyoshi Harashima
Pages: 8395-8410
Published online: 10 Dec 2018
AbstractforMixing lipids to manipulate the ionization status of lipid nanoparticles for specific tissue targeting | Full Text | References | PDF (2.8 MB)
  • 247 Views
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Article
A personalized and long-acting local therapeutic platform combining photothermal therapy and chemotherapy for the treatment of multidrug-resistant colon tumor
Beibei Wang, Sunyi Wu, Zhiqiang Lin, Yajun Jiang, Yan Chen, Zhe-Sheng Chen, Xiaoying Yang & Wei Gao
Pages: 8411-8427
Published online: 10 Dec 2018
AbstractforA personalized and long-acting local therapeutic platform combining photothermal therapy and chemotherapy for the treatment of multidrug-resistant colon tumor | Full Text | References | PDF (3.7 MB)
  • 83 Views
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Article
Exposure to high-frequency electromagnetic field triggers rapid uptake of large nanosphere clusters by pheochromocytoma cells
Palalle G Tharushi Perera, The Hong Phong Nguyen, Chaitali Dekiwadia, Jason V Wandiyanto, Igor Sbarski, Olga Bazaka, Kateryna Bazaka, Russell J Crawford, Rodney J Croft & Elena P Ivanova
Pages: 8429-8442
Published online: 10 Dec 2018
AbstractforExposure to high-frequency electromagnetic field triggers rapid uptake of large nanosphere clusters by pheochromocytoma cells | Full Text | References | PDF (2.4 MB)
  • 99 Views
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Article
Drug delivery to atherosclerotic plaques using superparamagnetic iron oxide nanoparticles
Jasmin Matuszak, Barbara Lutz, Aleksander Sekita, Jan Zaloga, Christoph Alexiou, Stefan Lyer & Iwona Cicha
Pages: 8443-8460
Published online: 11 Dec 2018
AbstractforDrug delivery to atherosclerotic plaques using superparamagnetic iron oxide nanoparticles | Full Text | References | PDF (1.9 MB)
  • 174 Views
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Article
Olaparib nanoparticles potentiated radiosensitization effects on lung cancer
Min Wu, Jing Liu, ChuanFei Hu, Dong Li, Juan Yang, ZhouXue Wu, LingLin Yang, Yue Chen, ShaoZhi Fu & JingBo Wu
Pages: 8461-8472
Published online: 11 Dec 2018
AbstractforOlaparib nanoparticles potentiated radiosensitization effects on lung cancer | Full Text | References | PDF (3.6 MB)
  • 145 Views
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Review

Review Article
Nanoparticle-conjugated nutraceuticals exert prospectively palliative of amyloid aggregation
Kiran Reddy Kanubaddi, Shin-Han Yang, Li-Wei Wu, Chia-Hung Lee & Ching-Feng Weng
Pages: 8473-8485
Published online: 11 Dec 2018
AbstractforNanoparticle-conjugated nutraceuticals exert prospectively palliative of amyloid aggregation | Full Text | References | PDF (820.3 KB)
  • 80 Views
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Review Article
Potential adverse effects of nanoparticles on the reproductive system
Ruolan Wang, Bin Song, Junrong Wu, Yanli Zhang, Aijie Chen & Longquan Shao
Pages: 8487-8506
Published online: 11 Dec 2018
AbstractforPotential adverse effects of nanoparticles on the reproductive system | Full Text | References | PDF (510.6 KB)
  • 543 Views
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Review Article
Liposome delivery systems for the treatment of Alzheimer’s disease
Callum Ross, Mark Taylor, Nigel Fullwood & David Allsop
Pages: 8507-8522
Published online: 12 Dec 2018
AbstractforLiposome delivery systems for the treatment of Alzheimer’s disease | Full Text | References | PDF (3.7 MB)
  • 591 Views
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Original Research

Article
Detection of Mycobacterium tuberculosis purified ESAT-6 (Rv3875) by magnetic bead-coupled gold nanoparticle-based immuno-PCR assay
Netrapal Singh, Bhawna Dahiya, Venkatraman Srinivasan Radhakrishnan, Tulika Prasad & Promod K Mehta
Pages: 8523-8535
Published online: 28 Feb 2023
AbstractforDetection of Mycobacterium tuberculosis purified ESAT-6 (Rv3875) by magnetic bead-coupled gold nanoparticle-based immuno-PCR assay | Full Text | References | PDF (3.1 MB)
  • 134 Views
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Article
Eco-friendly synthesis, characterization, in vitro and in vivo anti-inflammatory activity of silver nanoparticle-mediated Selaginella myosurus aqueous extract
Philippe Belle Ebanda Kedi, Francois Eya’ane Meva, Lebogang Kotsedi, Edwige Laure Nguemfo, Calvin Bogning Zangueu, Agnes Antoinette Ntoumba, Hamza Elsayed Ahmed Mohamed, Alain Bertrand Dongmo & Malik Maaza
Pages: 8537-8548
Published online: 28 Feb 2023
AbstractforEco-friendly synthesis, characterization, in vitro and in vivo anti-inflammatory activity of silver nanoparticle-mediated Selaginella myosurus aqueous extract | Full Text | References | PDF (2.4 MB)
  • 620 Views
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Article
Multispectral optoacoustic tomography (MSOT) for imaging the particle size-dependent intratumoral distribution of polymeric micelles
Zhaoqing Cong, Feifei Yang, Li Cao, Han Wen, Taotao Fu, Siqi Ma, Chunyu Liu, Lihui Quan & Yonghong Liao
Pages: 8549-8560
Published online: 12 Dec 2018
AbstractforMultispectral optoacoustic tomography (MSOT) for imaging the particle size-dependent intratumoral distribution of polymeric micelles | Full Text | References | PDF (5 MB)
  • 81 Views
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Article
Nanostructures of diamond, graphene oxide and graphite inhibit CYP1A2, CYP2D6 and CYP3A4 enzymes and downregulate their genes in liver cells
Barbara Strojny, Ewa Sawosz, Marta Grodzik, Sławomir Jaworski, Jarosław Szczepaniak, Malwina Sosnowska, Mateusz Wierzbicki, Marta Kutwin, Sylwia Orlińska & André Chwalibog
Pages: 8561-8575
Published online: 13 Dec 2018
AbstractforNanostructures of diamond, graphene oxide and graphite inhibit CYP1A2, CYP2D6 and CYP3A4 enzymes and downregulate their genes in liver cells | Full Text | References | PDF (5.1 MB)
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Erratum

Correction
Silica–gentamicin nanohybrids: combating antibiotic resistance, bacterial biofilms, and in vivo toxicity
Pages: 8577-8578
Published online: 28 Feb 2023
CitationforSilica–gentamicin nanohybrids: combating antibiotic resistance, bacterial biofilms, and in vivo toxicity | Full Text | PDF (1.9 MB)
  • 38 Views
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Original Research

Article
Antiviral efficacy of nanoparticulate vacuolar ATPase inhibitors against influenza virus infection
Che-Ming Jack Hu, You-Ting Chen, Zih-Syun Fang, Wei-Shan Chang & Hui-Wen Chen
Pages: 8579-8593
Published online: 14 Dec 2018
AbstractforAntiviral efficacy of nanoparticulate vacuolar ATPase inhibitors against influenza virus infection | Full Text | References | PDF (9.5 MB)
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