Drug Development and Industrial Pharmacy, Volume 45, Issue 1 (2019)

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Drug Development and Industrial Pharmacy, Volume 45, Issue 1 (2019)

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Review Article

Review Article
The utility of 3D-printed airway stents to improve treatment strategies for central airway obstructions
Jesse Xu, Hui X. Ong, Daniela Traini, Michael Byrom, Jonathan Williamson & Paul M. Young
Pages: 1-10
Published online: 25 Sep 2018
AbstractforThe utility of 3D-printed airway stents to improve treatment strategies for central airway obstructions | Full Text | References | PDF (1.4 MB) | EPUB
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Research Article

Article
Inhalable liposomes of Glycyrrhiza glabra extract for use in tuberculosis: formulation, in vitro characterization, in vivo lung deposition, and in vivo pharmacodynamic studies
Vivek Viswanathan, Rajesh Pharande, Anilkumar Bannalikar, Pushpa Gupta, Umesh Gupta & Alka Mukne
Pages: 11-20
Published online: 07 Sep 2018
AbstractforInhalable liposomes of Glycyrrhiza glabra extract for use in tuberculosis: formulation, in vitro characterization, in vivo lung deposition, and in vivo pharmacodynamic studies | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 357 Views
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Article
Scavenger receptor class BI (SR-BI) mediates uptake of CPX-351 into K562 leukemia cells
Yunyun Di, Ellen K. Wasan, Jacqueline Cawthray & Kishor M. Wasan
Pages: 21-26
Published online: 05 Sep 2018
AbstractforScavenger receptor class BI (SR-BI) mediates uptake of CPX-351 into K562 leukemia cells | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 203 Views
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Article
Inhibitory effect of resveratrol on the pharmacokinetic of ibrutinib by UPLC–MS/MS
Jian Wen, Su-Su Bao, Bo-Wen Zhang, Teng-Hui Liu, Qiu-Geng Ou-Yang, Jian-Ping Cai & Hong-Yu Zhou
Pages: 27-31
Published online: 28 Jan 2019
AbstractforInhibitory effect of resveratrol on the pharmacokinetic of ibrutinib by UPLC–MS/MS | Full Text | References | PDF (1.1 MB) | EPUB
  • 182 Views
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Article
Application of liquisolid technology for promoting the renoprotective efficacy of walnut extracts in chronic renal failure rat model
Sahar Youssef Al-Okbi, Doha Abdou Mohamed, Thanaa El-Sayed Hamed, Sameh Hosam Abd El-Alim, Ahmed Alaa Kassem & Dina Mahmoud Mostafa
Pages: 32-42
Published online: 11 Sep 2018
AbstractforApplication of liquisolid technology for promoting the renoprotective efficacy of walnut extracts in chronic renal failure rat model | Full Text | References | PDF (1.9 MB) | EPUB
  • 92 Views
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Article
Development of hydrophilic gels containing coenzyme Q10-loaded liposomes: characterization, stability and rheology measurements
Nina Dragicevic, Danina Krajisnik, Jela Milic, Alfred Fahr & Howard Maibach
Pages: 43-54
Published online: 11 Sep 2018
AbstractforDevelopment of hydrophilic gels containing coenzyme Q10-loaded liposomes: characterization, stability and rheology measurements | Full Text | References | PDF (2.2 MB) | EPUB
  • 336 Views
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Article
Fabrication of rosuvastatin-loaded polymeric nanocapsules: a promising modality for treating hepatic cancer delineated by apoptotic and cell cycle arrest assessment
Saed Aldalaen, Riham I. El-Gogary & Maha Nasr
Pages: 55-62
Published online: 16 Sep 2018
AbstractforFabrication of rosuvastatin-loaded polymeric nanocapsules: a promising modality for treating hepatic cancer delineated by apoptotic and cell cycle arrest assessment | Full Text | References | PDF (1.4 MB) | EPUB
  • 321 Views
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Article
SCC4 cell monolayers as an alternative sublingual barrier model: influence of nanoencapsulation on carvedilol transport
Paula dos Santos Chaves, Fernanda Visioli, Andréia Buffon, Adriana Raffin Pohlmann, Sílvia Stanisçuaski Guterres & Ruy Carlos Ruver Beck
Pages: 63-66
Published online: 19 Sep 2018
AbstractforSCC4 cell monolayers as an alternative sublingual barrier model: influence of nanoencapsulation on carvedilol transport | Full Text | References | PDF (790.1 KB) | EPUB
  • 128 Views
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Article
Complexation of novel thiomers and insulin to protect against in vitro enzymatic degradation – towards oral insulin delivery
C.O. Ibie, R.M. Knott & C.J. Thompson
Pages: 67-75
Published online: 25 Sep 2018
AbstractforComplexation of novel thiomers and insulin to protect against in vitro enzymatic degradation – towards oral insulin delivery | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 214 Views
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Article
Development and in vitro characterization of chitosan-coated polymeric nanoparticles for oral delivery and sustained release of the immunosuppressant drug mycophenolate mofetil
Munawar Mohammed, Holly Mansell, Ahmed Shoker, Kishor M. Wasan & Ellen K. Wasan
Pages: 76-87
Published online: 25 Sep 2018
AbstractforDevelopment and in vitro characterization of chitosan-coated polymeric nanoparticles for oral delivery and sustained release of the immunosuppressant drug mycophenolate mofetil | Full Text | References | PDF (2.9 MB) | EPUB
  • 345 Views
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Article
Targeted thrombolysis by using c-RGD-modified N,N,N-Trimethyl Chitosan nanoparticles loaded with lumbrokinase
Jie Liao, Xiaoting Ren, Bowen Yang, Hou Li, Yuexin Zhang & Zongning Yin
Pages: 88-95
Published online: 08 Oct 2018
AbstractforTargeted thrombolysis by using c-RGD-modified N,N,N-Trimethyl Chitosan nanoparticles loaded with lumbrokinase | Full Text | References | PDF (1.3 MB) | EPUB
  • 259 Views
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Article
Low molecular weight chitosan-based conjugates for efficient Rhein oral delivery: synthesis, characterization, and pharmacokinetics
Jingwen Luo, Jiang Sun, Xiaoting Luo, Yinghui Wei, Hangsheng Zheng, Chaofeng Mu & Wenjie Yao
Pages: 96-104
Published online: 26 Sep 2018
AbstractforLow molecular weight chitosan-based conjugates for efficient Rhein oral delivery: synthesis, characterization, and pharmacokinetics | Full Text | References | PDF (1.6 MB) | EPUB
  • 159 Views
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Article
Proof-of-concept preparation and characterization of dual-drug amorphous nanoparticle complex as fixed-dose combination of poorly soluble drugs
Hong Yu, Li Ming Lim, Bingxue Dong & Kunn Hadinoto
Pages: 105-116
Published online: 25 Sep 2018
AbstractforProof-of-concept preparation and characterization of dual-drug amorphous nanoparticle complex as fixed-dose combination of poorly soluble drugs | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 120 Views
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Article
Influence of punch geometry (head-flat diameter) and tooling type (‘B’ or ‘D’) on the physical–mechanical properties of formulation tablets
Harsh G. Shah, Rohit P. Dugar, HongHao Li, Vivek S. Dave & Rutesh H. Dave
Pages: 117-123
Published online: 24 Oct 2018
AbstractforInfluence of punch geometry (head-flat diameter) and tooling type (‘B’ or ‘D’) on the physical–mechanical properties of formulation tablets | Full Text | References | PDF (1.3 MB) | EPUB
  • 224 Views
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Article
Mechanism of enhanced oral absorption of akebia saponin D by a self-nanoemulsifying drug delivery system loaded with phospholipid complex
Yuhui Wang, Jinyang Shen, Xiaolin Yang, Ye Jin, Zhonglin Yang, Rufeng Wang, Fuming Zhang & Robert J. Linhardt
Pages: 124-129
Published online: 26 Oct 2018
AbstractforMechanism of enhanced oral absorption of akebia saponin D by a self-nanoemulsifying drug delivery system loaded with phospholipid complex | Full Text | References | PDF (992.1 KB) | EPUB
  • 246 Views
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Article
Dissolution or disintegration – substitution of dissolution by disintegration testing for a fixed dose combination product
Achim Grube, Claudia Gerlitzki & Michael Brendel
Pages: 130-138
Published online: 16 Oct 2018
AbstractforDissolution or disintegration – substitution of dissolution by disintegration testing for a fixed dose combination product | Full Text | References | PDF (1.4 MB) | EPUB
  • 540 Views
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Article
Assessment of lisdexamfetamine dimesylate stability and identification of its degradation product by NMR spectroscopy
Graciela Carlos, Alvicler Magalhães, Ana Cristina Isler, Eloisa Comiran & Pedro Eduardo Fröehlich
Pages: 139-146
Published online: 01 Nov 2018
AbstractforAssessment of lisdexamfetamine dimesylate stability and identification of its degradation product by NMR spectroscopy | Full Text | References | PDF (2.2 MB) | EPUB
  • 330 Views
  • 1 CrossRef citations
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Article
Brain targeting of chitosan-based diazepam mucoadhesive microemulsions via nasal route: formulation optimization, characterization, pharmacokinetic and pharmacodynamic evaluation
Srividya Ramreddy & Krishnaveni Janapareddi
Pages: 147-158
Published online: 24 Oct 2018
AbstractforBrain targeting of chitosan-based diazepam mucoadhesive microemulsions via nasal route: formulation optimization, characterization, pharmacokinetic and pharmacodynamic evaluation | Full Text | References | PDF (2.6 MB) | EPUB
  • 298 Views
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Article
Research on the relationship between cephalosporin structure, solution clarity, and rubber closure compatibility using volatile components profile of butyl rubber closures
Xiao-Meng Chong, Xin Dong, Shang-Chen Yao & Chang-Qin Hu
Pages: 159-167
Published online: 24 Oct 2018
AbstractforResearch on the relationship between cephalosporin structure, solution clarity, and rubber closure compatibility using volatile components profile of butyl rubber closures | Full Text | References | PDF (2.1 MB) | EPUB
  • 81 Views
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Article
Physicochemical characterization and thermal behavior of hexosomes containing ketoconazole as potential topical antifungal delivery system
César Gazga-Urioste, Ernesto Rivera-Becerril, Gerardo Pérez-Hernández, Norma Angélica Noguez-Méndez, Abraham Faustino-Vega & Carlos Tomás Quirino-Barreda
Pages: 168-176
Published online: 17 Oct 2018
AbstractforPhysicochemical characterization and thermal behavior of hexosomes containing ketoconazole as potential topical antifungal delivery system | Full Text | References | PDF (1.5 MB) | EPUB
  • 213 Views
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