Modern Rheumatology, Volume 25, Issue 1 (2015)

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Modern Rheumatology, Volume 25, Issue 1 (2015)

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Review Article

Review Article
Pathogenesis of systemic inflammatory diseases in childhood: “Lessons from clinical trials of anti-cytokine monoclonal antibodies for Kawasaki disease, systemic onset juvenile idiopathic arthritis, and cryopyrin-associated periodic fever syndrome”
Shumpei Yokota, Masako Kikuchi, Tomo Nozawa, Taichi Kanetaka, Tomomi Sato, Kazuko Yamazaki, Nodoka Sakurai, Ryoki Hara & Masaaki Mori
Pages: 1-10
Published online: 20 May 2014
AbstractforPathogenesis of systemic inflammatory diseases in childhood: “Lessons from clinical trials of anti-cytokine monoclonal antibodies for Kawasaki disease, systemic onset juvenile idiopathic arthritis, and cryopyrin-associated periodic fever syndrome” | Full Text | References | PDF (216.7 KB)
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Original Article

Article
Early response to certolizumab pegol predicts long-term outcomes in patients with active rheumatoid arthritis: results from the Japanese studies
Tsutomu Takeuchi, Kazuhiko Yamamoto, Hisashi Yamanaka, Naoki Ishiguro, Yoshiya Tanaka, Katsumi Eguchi, Akira Watanabe, Hideki Origasa, Toshiharu Shoji, Nobuyuki Miyasaka & Takao Koike
Pages: 11-20
Published online: 20 May 2014
AbstractforEarly response to certolizumab pegol predicts long-term outcomes in patients with active rheumatoid arthritis: results from the Japanese studies | Full Text | References | PDF (927.2 KB) | Supplemental
  • 1702 Views
  • 10 CrossRef citations
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Open Access
Article
Efficacy and safety of mavrilimumab in Japanese subjects with rheumatoid arthritis: Findings from a Phase IIa study
Tsutomu Takeuchi, Yoshiya Tanaka, David Close, Alex Godwood, Chi-Yuan Wu & Didier Saurigny
Pages: 21-30
Published online: 11 Apr 2014
AbstractforEfficacy and safety of mavrilimumab in Japanese subjects with rheumatoid arthritis: Findings from a Phase IIa study | Full Text | References | PDF (1.7 MB)
  • 620 Views
  • 34 CrossRef citations
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Article
Tocilizumab is clinically, functionally, and radiographically effective and safe either with or without low-dose methotrexate in active rheumatoid arthritis patients with inadequate responses to DMARDs and/or TNF inhibitors: A single-center retrospective cohort study (KEIO-TCZ study) at week 52
Keisuke Izumi, Yuko Kaneko, Hidekata Yasuoka, Noriyuki Seta, Hideto Kameda, Masataka Kuwana & Tsutomu Takeuchi
Pages: 31-37
Published online: 01 Apr 2014
AbstractforTocilizumab is clinically, functionally, and radiographically effective and safe either with or without low-dose methotrexate in active rheumatoid arthritis patients with inadequate responses to DMARDs and/or TNF inhibitors: A single-center retrospective cohort study (KEIO-TCZ study) at week 52 | Full Text | References | PDF (736.3 KB)
  • 649 Views
  • 15 CrossRef citations
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Article
Remarkable efficacy of tocilizumab for treating rheumatoid arthritis in patients with high platelet counts
Hiroaki Matsuno
Pages: 38-42
Published online: 22 Dec 2014
AbstractforRemarkable efficacy of tocilizumab for treating rheumatoid arthritis in patients with high platelet counts | Full Text | References | PDF (629.6 KB)
  • 1197 Views
  • 7 CrossRef citations
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Open Access
Article
Obstacles to the implementation of the treat-to-target strategy for rheumatoid arthritis in clinical practice in Japan
Yuko Kaneko, Takao Koike, Hiromi Oda, Kazuhiko Yamamoto, Nobuyuki Miyasaka, Masayoshi Harigai, Hisashi Yamanaka, Naoki Ishiguro, Yoshiya Tanaka & Tsutomu Takeuchi
Pages: 43-49
Published online: 20 Jun 2014
AbstractforObstacles to the implementation of the treat-to-target strategy for rheumatoid arthritis in clinical practice in Japan | Full Text | References | PDF (1.6 MB) | Supplemental
  • 376 Views
  • 10 CrossRef citations
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Article
Inhibition of radiographic joint damage in rheumatoid arthritis patients in DAS28 remission using single- or combined with methotrexate non biological disease-modifying antirheumatic drug therapy in routine clinical practice
Kou Katayama, Takanobu Okubo, Toshikazu Sato, Hiroshi Ito, Richio Fukai & Hisashi Baba
Pages: 50-55
Published online: 01 Jul 2014
AbstractforInhibition of radiographic joint damage in rheumatoid arthritis patients in DAS28 remission using single- or combined with methotrexate non biological disease-modifying antirheumatic drug therapy in routine clinical practice | Full Text | References | PDF (327.2 KB)
  • 257 Views
  • 4 CrossRef citations
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Article
Severe low back pain in patients with rheumatoid arthritis is associated with Disease Activity Score but not with radiological findings on plain X-rays
Kentaro Yamada, Akinobu Suzuki, Shinji Takahashi, Hiroyuki Yasuda, Tatsuya Koike & Hiroaki Nakamura
Pages: 56-61
Published online: 19 Jun 2014
AbstractforSevere low back pain in patients with rheumatoid arthritis is associated with Disease Activity Score but not with radiological findings on plain X-rays | Full Text | References | PDF (294.4 KB)
  • 219 Views
  • 16 CrossRef citations
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Article
Long-term outcome of 114 adult JIA patients in a non-pediatric rheumatology institute in Japan
Takako Miyamae, Eiichi Tanaka, Takayuki Kishi, Tsuyoshi Matsuyama, Tohru Igarashi, Satoshi Fujikawa, Atsuo Taniguchi, Shigeki Momohara & Hisashi Yamanaka
Pages: 62-66
Published online: 14 Jul 2014
AbstractforLong-term outcome of 114 adult JIA patients in a non-pediatric rheumatology institute in Japan | Full Text | References | PDF (543.2 KB)
  • 255 Views
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Article
Association of polymorphisms in SPARC and NLRP2 genes with rheumatoid arthritis in a Chinese Han population
Xing-lin Yang, Zhong-dan Hu, Qian Wu, Xi Liu, Qi-ji Liu, Yuan-chao Zhang & Qing-rui Yang
Pages: 67-71
Published online: 23 Apr 2014
AbstractforAssociation of polymorphisms in SPARC and NLRP2 genes with rheumatoid arthritis in a Chinese Han population | Full Text | References | PDF (177.2 KB)
  • 139 Views
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Article
TNFα, PDGF, and TGFβ synergistically induce synovial lining hyperplasia via inducible PI3Kδ
Hideyuki Shibuya, Hiroyuki Yoshitomi, Koichi Murata, Shio Kobayashi, Moritoshi Furu, Masahiro Ishikawa, Takayuki Fujii, Hiromu Ito & Shuichi Matsuda
Pages: 72-78
Published online: 09 Apr 2014
AbstractforTNFα, PDGF, and TGFβ synergistically induce synovial lining hyperplasia via inducible PI3Kδ | Full Text | References | PDF (1.4 MB) | Supplemental
  • 272 Views
  • 15 CrossRef citations
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Article
Effects of anti-IL-6 receptor antibody on human monocytes
Toshihiro Tono, Satoko Aihara, Takayuki Hoshiyama, Yoshiyuki Arinuma, Tatsuo Nagai & Shunsei Hirohata
Pages: 79-84
Published online: 20 May 2014
AbstractforEffects of anti-IL-6 receptor antibody on human monocytes | Full Text | References | PDF (947 KB)
  • 352 Views
  • 11 CrossRef citations
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Article
Serum interferon-α is a useful biomarker in patients with anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis
Yoshiro Horai, Tomohiro Koga, Keita Fujikawa, Ayuko Takatani, Ayako Nishino, Yoshikazu Nakashima, Takahisa Suzuki, Shin-ya Kawashiri, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Hiroaki Ida, Tomoyuki Kakugawa, Noriho Sakamoto, Yuji Ishimatsu, Hiroshi Mukae, Yasuhito Hamaguchi, Manabu Fujimoto, Masataka Kuwana, Tomoki Origuchi, Shigeru Kohno & Atsushi Kawakami
Pages: 85-89
Published online: 09 Apr 2014
AbstractforSerum interferon-α is a useful biomarker in patients with anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis | Full Text | References | PDF (523.5 KB)
  • 743 Views
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Article
Decreased expression of Runx1 and lowered proportion of Foxp3+ CD25+ CD4+ regulatory T cells in systemic sclerosis
Hiroshi Kataoka, Shinsuke Yasuda, Shinji Fukaya, Kenji Oku, Tetsuya Horita, Tatsuya Atsumi & Takao Koike
Pages: 90-95
Published online: 09 Apr 2014
AbstractforDecreased expression of Runx1 and lowered proportion of Foxp3+ CD25+ CD4+ regulatory T cells in systemic sclerosis | Full Text | References | PDF (1.1 MB)
  • 173 Views
  • 23 CrossRef citations
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Article
Genetic variants of DNMT3A and systemic lupus erythematosus susceptibility
Piotr Piotrowski, Malwina K. Grobelna, Mariusz Wudarski, Marzena Olesińska & Paweł P. Jagodziński
Pages: 96-99
Published online: 09 Apr 2014
AbstractforGenetic variants of DNMT3A and systemic lupus erythematosus susceptibility | Full Text | References | PDF (1.1 MB) | Supplemental
  • 107 Views
  • 4 CrossRef citations
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Article
Efficient diagnosis of Sjögren's syndrome to reduce the burden on patients
Asumi J. Niikura, Shigeo Yamachika, Ken Yamamoto, Mariko R. Okamoto, Yuko F. Ikeda, Sachika Nakamura, Etsuko Oda, Takahiro K. Imamura, Ichiro Saito & Yoichi Nakagawa
Pages: 100-104
Published online: 12 Jun 2014
AbstractforEfficient diagnosis of Sjögren's syndrome to reduce the burden on patients | Full Text | References | PDF (203 KB)
  • 222 Views
  • 2 CrossRef citations
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Article
Clinical features of patients with IgG4-related disease complicated with perivascular lesions
Hiroshi Ebe, Hiroto Tsuboi, Chihiro Hagiya, Hiroyuki Takahashi, Masahiro Yokosawa, Shinya Hagiwara, Tomoya Hirota, Yuko Kurashima, Chinatsu Takai, Haruka Miki, Hiromitsu Asashima, Naoto Umeda, Yuya Kondo, Hiroshi Ogishima, Takeshi Suzuki, Yusuke Chino, Isao Matsumoto & Takayuki Sumida
Pages: 105-109
Published online: 23 Apr 2014
AbstractforClinical features of patients with IgG4-related disease complicated with perivascular lesions | Full Text | References | PDF (769.3 KB) | Supplemental
  • 281 Views
  • 18 CrossRef citations
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Article
Increased frequency of circulating follicular helper T cells in patients with ankylosing spondylitis
Shanshan Wu, Ting Yang, Faming Pan, Guo Xia, Yanting Hu, Li Liu, Dazhi Fan, Zhenhua Duan, Ning Ding, Shengqian Xu, Guoqi Cai & Li Wang
Pages: 110-115
Published online: 09 Apr 2014
AbstractforIncreased frequency of circulating follicular helper T cells in patients with ankylosing spondylitis | Full Text | References | PDF (2.1 MB)
  • 202 Views
  • 14 CrossRef citations
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Article
Validation and additional support for an experimental animal model of fibromyalgia
Sergio Montserrat-de la Paz, M. Dolores García-Giménez, Maria Ángel-Martín & Angeles Fernández-Arche
Pages: 116-122
Published online: 01 Jul 2014
AbstractforValidation and additional support for an experimental animal model of fibromyalgia | Full Text | References | PDF (325.7 KB)
  • 257 Views
  • 13 CrossRef citations
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Article
Changes of plasma concentration of osteoprotegerin and its association with endothelial dysfunction before and after hypouricemic therapy in patients with hyperuricemia
Hao-hua Wang & Guang-da Xiang
Pages: 123-127
Published online: 20 Jun 2014
AbstractforChanges of plasma concentration of osteoprotegerin and its association with endothelial dysfunction before and after hypouricemic therapy in patients with hyperuricemia | Full Text | References | PDF (474.3 KB)
  • 144 Views
  • 9 CrossRef citations
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Article
Ultrasonographic assessment of pes anserinus tendon and pes anserinus tendinitis bursitis syndrome in patients with knee osteoarthritis
Hasan Toktas, Umit Dundar, Sevda Adar, Ozlem Solak & Alper Murat Ulasli
Pages: 128-133
Published online: 18 Jul 2014
AbstractforUltrasonographic assessment of pes anserinus tendon and pes anserinus tendinitis bursitis syndrome in patients with knee osteoarthritis | Full Text | References | PDF (818.9 KB)
  • 362 Views
  • 11 CrossRef citations
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Case Report

Case Report
Expansion of range of joint motion following treatment of systemic sclerosis with tocilizumab
Yoshihito Shima, Naoki Hosen, Toru Hirano, Junsuke Arimitsu, Sumiyuki Nishida, Keisuke Hagihara, Masashi Narazaki, Atsushi Ogata, Toshio Tanaka, Tadamitsu Kishimoto & Atsushi Kumanogoh
Pages: 134-137
Published online: 18 Feb 2014
AbstractforExpansion of range of joint motion following treatment of systemic sclerosis with tocilizumab | Full Text | References | PDF (794.6 KB)
  • 1366 Views
  • 23 CrossRef citations
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Open Access
Case Report
Tocilizumab improves systemic rheumatoid vasculitis with necrotizing crescentic glomerulonephritis
Takashi Iijima, Tatsuya Suwabe, Keiichi Sumida, Noriko Hayami, Rikako Hiramatsu, Eiko Hasegawa, Masayuki Yamanouchi, Junichi Hoshino, Naoki Sawa, Kenmei Takaichi, Kenichi Oohashi, Takeshi Fujii & Yoshifumi Ubara
Pages: 138-142
Published online: 18 Feb 2014
AbstractforTocilizumab improves systemic rheumatoid vasculitis with necrotizing crescentic glomerulonephritis | Full Text | References | PDF (2.8 MB)
  • 495 Views
  • 22 CrossRef citations
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Case Report
Two cases of refractory polymyositis accompanied with steroid myopathy
Yasumori Izumi, Taiichiro Miyashita, Tsubasa Kitajima, Shunsuke Yoshimura, Atsushi Takeoka, Katsumi Eguchi, Masakatsu Motomura, Atsushi Kawakami & Kiyoshi Migita
Pages: 143-149
Published online: 18 Feb 2014
AbstractforTwo cases of refractory polymyositis accompanied with steroid myopathy | Full Text | References | PDF (786.5 KB)
  • 276 Views
  • 7 CrossRef citations
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Case Report
A case of catastrophic antiphospholipid syndrome, which presented an acute interstitial pneumonia-like image on chest CT scan
Tomohiro Kameda, Hiroaki Dobashi, Kentaro Susaki, Junichi Danjo, Shusaku Nakashima, Hiromi Shimada, Miharu Izumikawa, Yohei Takeuchi, Hiroki Mitsunaka, Shuji Bandoh, Osamu Imataki, Masato Nose & Takuya Matsunaga
Pages: 150-153
Published online: 18 Feb 2014
AbstractforA case of catastrophic antiphospholipid syndrome, which presented an acute interstitial pneumonia-like image on chest CT scan | Full Text | References | PDF (658.2 KB)
  • 163 Views
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Case Report
Successful leukocytapheresis therapy in a patient with rheumatoid arthritis on maintenance hemodialysis
Keisuke Maeshima, Masataka Torigoe, Mikako Iwakura, Kunitoshi Yamanaka & Koji Ishii
Pages: 154-157
Published online: 11 Feb 2014
AbstractforSuccessful leukocytapheresis therapy in a patient with rheumatoid arthritis on maintenance hemodialysis | Full Text | References | PDF (252.1 KB)
  • 131 Views
  • 1 CrossRef citations
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Rapid Communication

Rapid Communication
M3 muscarinic acetylcholine receptor reactive IL-17 producing T cells promotes development of Sjögren's syndrome like sialadenitis
Mana Iizuka, Hiroto Tsuboi, Hiromitsu Asashima, Tomoya Hirota, Yuya Kondo, Minoru Matsui, Isao Matsumoto & Takayuki Sumida
Pages: 158-160
Published online: 04 Mar 2014
First Page PreviewforM3 muscarinic acetylcholine receptor reactive IL-17 producing T cells promotes development of Sjögren's syndrome like sialadenitis | Full Text | References | PDF (4.7 MB)
  • 212 Views
  • 8 CrossRef citations
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Rapid Communication
Clinical characteristics of Japanese patients with reactive arthritis following intravesical BCG therapy for bladder cancer
Yoshinori Taniguchi, Takashi Karashima, Yasuhiko Yoshinaga, Taro Shuin, Shimpei Fujimoto & Yoshio Terada
Pages: 161-163
Published online: 20 Jun 2014
First Page PreviewforClinical characteristics of Japanese patients with reactive arthritis following intravesical BCG therapy for bladder cancer | Full Text | References | PDF (3 MB)
  • 224 Views
  • 7 CrossRef citations
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Letter

Letter
Ultrasound examination of wrist compartments in swollen wrists of patients with rheumatoid arthritis
Jae Ho Lee, Seung-Ki Kwok, Ji Hyeon Ju, Sung-Hwan Park & Kyung-Su Park
Pages: 164-165
Published online: 28 Jan 2014
CitationforUltrasound examination of wrist compartments in swollen wrists of patients with rheumatoid arthritis | Full Text | References | PDF (296.2 KB)
  • 137 Views
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Letter
Epstein-Barr virus-related MTX-LPD in rheumatoid arthritis patients exhibits a viral pattern of the CD64 and CD35 expression on neutrophils: Three case reports
Sho Mokuda, Tatsuhiko Miyazaki, Yukari Saeki, Junya Masumoto, Masamoto Kanno & Kiyoshi Takasugi
Pages: 166-168
Published online: 05 Feb 2014
First Page PreviewforEpstein-Barr virus-related MTX-LPD in rheumatoid arthritis patients exhibits a viral pattern of the CD64 and CD35 expression on neutrophils: Three case reports | Full Text | References | PDF (621 KB)
  • 245 Views
  • 5 CrossRef citations
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Lists of Reviewers

List of reviewers
Pages: 169-172
Published online: 22 Dec 2014
First Page PreviewforList of reviewers | Full Text | PDF (537.3 KB)
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