Pharmaceutical Development and Technology, Volume 18, Issue 2 (2013)

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Pharmaceutical Development and Technology, Volume 18, Issue 2 (2013)

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Review Article

Review Article
Formulation approaches in mitigating toxicity of orally administrated drugs
Irina Kadiyala & Elijah Tan
Pages: 305-312
Published online: 14 Jan 2013
AbstractforFormulation approaches in mitigating toxicity of orally administrated drugs | Full Text | References | PDF (619.1 KB)
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Research Article

Article
Inclusion complex of colchicine in hydroxypropyl-β-cyclodextrin tenders better solubility and improved pharmacokinetics
Ritu Chauhan, Jitender Madan, Dinesh Kaushik, Satish Sardana, Ravi Shankar Pandey & Rakesh Sharma
Pages: 313-322
Published online: 23 Jun 2011
AbstractforInclusion complex of colchicine in hydroxypropyl-β-cyclodextrin tenders better solubility and improved pharmacokinetics | Full Text | References | PDF (926.8 KB)
  • 224 Views
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Article
Preparation and Characterization of Tablet Formulation based on Solid Dispersion of Glimepiride and Poly(ester amide) Hyperbranched Polymer
Sebastjan Reven, Miha Homar, Luka Peternel, Julijana Kristl & Ema Žagar
Pages: 323-332
Published online: 03 Aug 2011
AbstractforPreparation and Characterization of Tablet Formulation based on Solid Dispersion of Glimepiride and Poly(ester amide) Hyperbranched Polymer | Full Text | References | PDF (911.5 KB)
  • 306 Views
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Article
Utilizing quantitative certificate of analysis data to assess the amount of excipient lot-to-lot variability sampled during drug product development
Joseph Kushner IV
Pages: 333-342
Published online: 30 Aug 2011
AbstractforUtilizing quantitative certificate of analysis data to assess the amount of excipient lot-to-lot variability sampled during drug product development | Full Text | References | PDF (864.4 KB)
  • 515 Views
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Article
The influence of HPMC viscosity as FRC parameter on the release of low soluble drug from hydrophylic matrix tablets
S. Devjak Novak, V. Kuhelj, F. Vrečer & S. Baumgartner
Pages: 343-347
Published online: 14 Sep 2011
AbstractforThe influence of HPMC viscosity as FRC parameter on the release of low soluble drug from hydrophylic matrix tablets | Full Text | References | PDF (680.2 KB)
  • 214 Views
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Article
Efficient throughput method for hygroscopicity classification of active and inactive pharmaceutical ingredients by water vapor sorption analysis
Vasudha Murikipudi, Piyush Gupta & Vaibhav Sihorkar
Pages: 348-358
Published online: 10 Oct 2011
AbstractforEfficient throughput method for hygroscopicity classification of active and inactive pharmaceutical ingredients by water vapor sorption analysis | Full Text | References | PDF (834.5 KB)
  • 702 Views
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Article
Formulation and process design for a solid dosage form containing a spray-dried amorphous dispersion of ibipinabant
Michael M. Leane, Wayne Sinclair, Feng Qian, Raja Haddadin, Alan Brown, Mike Tobyn & Andrew B. Dennis
Pages: 359-366
Published online: 23 Jan 2012
AbstractforFormulation and process design for a solid dosage form containing a spray-dried amorphous dispersion of ibipinabant | Full Text | References | PDF (887.8 KB)
  • 595 Views
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Article
Formulation and development of taste masked fast-disintegrating tablets (FDTs) of Chlorpheniramine maleate using ion-exchange resins
Chetan P. Yewale, Mohan N. Rathi, Girish G. Kore, Ganesh V. Jadhav & Milind P. Wagh
Pages: 367-376
Published online: 24 Oct 2011
AbstractforFormulation and development of taste masked fast-disintegrating tablets (FDTs) of Chlorpheniramine maleate using ion-exchange resins | Full Text | References | PDF (1 MB)
  • 291 Views
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Article
Influence of surfactants on the release behaviour and structural properties of sol-gel derived silica xerogels embedded with metronidazole
Katarzyna Czarnobaj & Wiesław Sawicki
Pages: 377-383
Published online: 22 Nov 2011
AbstractforInfluence of surfactants on the release behaviour and structural properties of sol-gel derived silica xerogels embedded with metronidazole | Full Text | References | PDF (819.6 KB)
  • 78 Views
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Article
Formulation study of directly compressible chewable polymers containing ascorbic acid
P. Kása, I. Jójárt, A. Kelemen & K. Pintye-Hódi
Pages: 384-389
Published online: 10 Jan 2012
AbstractforFormulation study of directly compressible chewable polymers containing ascorbic acid | Full Text | References | PDF (806.3 KB)
  • 196 Views
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Article
Development of a novel tablet-in-capsule formulation of mesalamine for inflammatory bowel disease
Mayur M. Patel & Avani F. Amin
Pages: 390-400
Published online: 05 Feb 2012
AbstractforDevelopment of a novel tablet-in-capsule formulation of mesalamine for inflammatory bowel disease | Full Text | References | PDF (1.5 MB)
  • 378 Views
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Article
Design and evaluation of enteric-coated tablets for rifampicin and isoniazid combinations
Yongjun Wang, Hongzhuo Liu, Kai Liu, Jin Sun & Zhonggui He
Pages: 401-406
Published online: 18 Feb 2012
AbstractforDesign and evaluation of enteric-coated tablets for rifampicin and isoniazid combinations | Full Text | References | PDF (925 KB)
  • 243 Views
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Article
Rapidly absorbed orodispersible tablet containing molecularly dispersed felodipine for management of hypertensive crisis: Development, optimization and in vitro/in vivo studies
Emad B. Basalious, Wessam El-Sebaie & Omaima El-Gazayerly
Pages: 407-416
Published online: 18 Feb 2012
AbstractforRapidly absorbed orodispersible tablet containing molecularly dispersed felodipine for management of hypertensive crisis: Development, optimization and in vitro/in vivo studies | Full Text | References | PDF (949.1 KB)
  • 213 Views
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Article
Formulation factors affecting the release of ezetimibe from different liquisolid compacts
M. Khanfar, M. Sheikh Salem & R. Hawari
Pages: 417-427
Published online: 24 Apr 2012
AbstractforFormulation factors affecting the release of ezetimibe from different liquisolid compacts | Full Text | References | PDF (1.3 MB)
  • 186 Views
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Article
Solid dosage forms for active antiretroviral therapy (HAART): dissolution profile study of nevirapine by experimental factorial design
G. G. G. de Oliveira, H. Ferraz, P. Severino & E. B. Souto
Pages: 428-433
Published online: 21 Apr 2012
AbstractforSolid dosage forms for active antiretroviral therapy (HAART): dissolution profile study of nevirapine by experimental factorial design | Full Text | References | PDF (855.2 KB)
  • 114 Views
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Article
Enhanced dissolution and systemic availability of albendazole formulated as solid dispersions
Silvina G. Castro, Sergio F. Sanchez Bruni, Lucía P. Urbizu, Alejandra Confalonieri, Laura Ceballos, Carlos E. Lanusse, Daniel A. Allemandi & Santiago D. Palma
Pages: 434-442
Published online: 07 Jun 2012
AbstractforEnhanced dissolution and systemic availability of albendazole formulated as solid dispersions | Full Text | References | PDF (1.1 MB)
  • 198 Views
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Article
Hydrochloride salt co-crystals: preparation, characterization and physicochemical studies
Vijaykumar K. Parmar & Shailesh A. Shah
Pages: 443-453
Published online: 11 Jun 2012
AbstractforHydrochloride salt co-crystals: preparation, characterization and physicochemical studies | Full Text | References | PDF (1.4 MB)
  • 536 Views
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Article
Development and optimization of dextromethorphan hydrobromide oral disintegrating tablets: effect of formulation and process variables
Haitham Fady Mostafa, Mohamed Abbas Ibrahim & Adel Sakr
Pages: 454-463
Published online: 13 Aug 2012
AbstractforDevelopment and optimization of dextromethorphan hydrobromide oral disintegrating tablets: effect of formulation and process variables | Full Text | References | PDF (1.1 MB)
  • 331 Views
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Article
Evaluation of co-processed excipients used for direct compression of orally disintegrating tablets (ODT) using novel disintegration apparatus
Witold Brniak, Renata Jachowicz, Anna Krupa, Tomasz Skorka & Krzysztof Niwinski
Pages: 464-474
Published online: 13 Aug 2012
AbstractforEvaluation of co-processed excipients used for direct compression of orally disintegrating tablets (ODT) using novel disintegration apparatus | Full Text | References | PDF (1.1 MB)
  • 698 Views
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Article
Enhanced dissolution performance of curcumin with the use of supersaturatable formulations
Saujanya Gosangari & Tatyana Dyakonov
Pages: 475-480
Published online: 13 Aug 2012
AbstractforEnhanced dissolution performance of curcumin with the use of supersaturatable formulations | Full Text | References | PDF (812.8 KB)
  • 387 Views
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Article
Solid-state compatibility screening of excipients suitable for development of indapamide sustained release solid-dosage formulation
Packa Antovska, Gjorgji Petruševski & Petre Makreski
Pages: 481-489
Published online: 24 Sep 2012
AbstractforSolid-state compatibility screening of excipients suitable for development of indapamide sustained release solid-dosage formulation | Full Text | References | PDF (1 MB) | Supplemental
  • 161 Views
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Article
Understanding and optimizing the dual excipient functionality of sodium lauryl sulfate in tablet formulation of poorly water soluble drug: wetting and lubrication
Ahmad Aljaberi, Ashish Chatterji, Zedong Dong, Navnit H. Shah, Waseem Malick, Dharmendra Singhal & Harpreet K. Sandhu
Pages: 490-503
Published online: 26 Sep 2012
AbstractforUnderstanding and optimizing the dual excipient functionality of sodium lauryl sulfate in tablet formulation of poorly water soluble drug: wetting and lubrication | Full Text | References | PDF (2.3 MB)
  • 635 Views
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Article
Characterization, quantification and stability of differently prepared amorphous forms of some oral hypoglycaemic agents
Renu Chadha, Swati Bhandari, Poonam Arora & Rekha Chhikara
Pages: 504-514
Published online: 15 Oct 2012
AbstractforCharacterization, quantification and stability of differently prepared amorphous forms of some oral hypoglycaemic agents | Full Text | References | PDF (1.3 MB) | Supplemental
  • 145 Views
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Article
Design and statistical optimization of osmotically driven capsule based on push-pull technology
Wasim Shaikh, Prashant K. Deshmukh, Ganesh B. Patil, Vivekanand K. Chatap & Sanjay B. Bari
Pages: 515-524
Published online: 04 Oct 2012
AbstractforDesign and statistical optimization of osmotically driven capsule based on push-pull technology | Full Text | References | PDF (1.3 MB)
  • 115 Views
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Article
Solid-state characterization and dissolution properties of Fluvastatin sodium salt hydrates
Silvia H. M. Borgmann, Larissa S. Bernardi, Gabriela S. Rauber, Paulo R. Oliveira, Carlos E. M. Campos, Gustavo Monti, Silvia L. Cuffini & Simone G. Cardoso
Pages: 525-534
Published online: 04 Oct 2012
AbstractforSolid-state characterization and dissolution properties of Fluvastatin sodium salt hydrates | Full Text | References | PDF (913.9 KB)
  • 219 Views
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Technical Note

New immediate release formulation for deterring abuse of methadone
A. O. Betancourt, P. M. Gosselin & R. K. Vinson
Pages: 535-543
Published online: 27 Apr 2012
AbstractforNew immediate release formulation for deterring abuse of methadone | Full Text | References | PDF (708.2 KB)
  • 253 Views
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Book Review

Book Review
Handbook of Pharmaceutical Excipients – 7th Edition
Page: 544
Published online: 14 Jan 2013
CitationforHandbook of Pharmaceutical Excipients – 7th Edition | Full Text | PDF (543.3 KB)
  • 7816 Views
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