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Research Article

Clodronate prevents prosthetic migration: A randomized radiostereometric study of 50 total knee patients

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Pages 553-557 | Published online: 08 Jul 2009

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Read on this site (17)

Wen-bin Liu, Wen-tao Zhao, Peng Shen & Fu-jiang Zhang. (2018) The effects of bisphosphonates on osteoporotic patients after lumbar fusion: a meta-analysis. Drug Design, Development and Therapy 12, pages 2233-2240.
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Håkan Ledin, Lars Good & Per Aspenberg. (2017) Denosumab reduces early migration in total knee replacement. Acta Orthopaedica 88:3, pages 255-258.
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Håkan Ledin, Lars Good, Torsten Johansson & Per Aspenberg. (2017) No effect of teriparatide on migration in total knee replacement. Acta Orthopaedica 88:3, pages 259-262.
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Rami Madanat, Tatu J Mäkinen, Hannu T Aro, Charles Bragdon & Henrik Malchau. (2014) Adherence of hip and knee arthroplasty studies to RSA standardization guidelines. Acta Orthopaedica 85:5, pages 447-455.
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Håkan Ledin, Per Aspenberg & Lars Good. (2012) Tourniquet use in total knee replacement does not improve fixation, but appears to reduce final range of motion. Acta Orthopaedica 83:5, pages 499-503.
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Anna Fahlgren, Mathias PG Bostrom, Xu Yang, Lars Johansson, Ulf Edlund, Fredrik Agholme & Per Aspenberg. (2010) Fluid pressure and flow as a cause of bone resorption. Acta Orthopaedica 81:4, pages 508-516.
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Theis Muncholm Thillemann. (2009) Use of medications and risk of revision after primary total hip arthroplasty. Acta Orthopaedica 80:338, pages 1-36.
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Per Aspenberg. (2009) Bisphosphonates and implants. Acta Orthopaedica 80:1, pages 119-123.
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Andreas Meunier, Per Aspenberg & Lars Good. (2009) Celecoxib does not appear to affect prosthesis fixation in total knee replacement. Acta Orthopaedica 80:1, pages 46-50.
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Ulrik Hansson, Sören Toksvig-Larsen, Leif Ryd & Per Aspenberg. (2009) Once-weekly oral medication with alendronate does not prevent migration of knee prostheses. Acta Orthopaedica 80:1, pages 41-45.
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Karin Wermelin, Pentti Tengvall & Per Aspenberg. (2007) Surface-bound bisphosphonates enhance screw fixation in rats—increasing effect up to 8 weeks after insertion. Acta Orthopaedica 78:3, pages 385-392.
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Magnus Tägil, Per Aspenberg & Jörgen Åstrand. (2006) Systemic zoledronate precoating of a bone graft reduces bone resorption during remodeling. Acta Orthopaedica 77:1, pages 23-26.
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M. J. Phillips, P. Duncanson, K. Wilson, J. A. Darr, D. V. Griffiths & I. Rehman. (2005) Surface modification of bioceramics by grafting of tailored allyl phosphonic acid. Advances in Applied Ceramics 104:5, pages 261-267.
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Per Aspenberg. (2005) Postoperative Cox inhibitors and late prosthetic loosening—suspicion increases!. Acta Orthopaedica 76:6, pages 733-734.
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Per Aspenberg. (2002) Avoid cox inhibitors after skeletal surgery!. Acta Orthopaedica Scandinavica 73:5, pages 489-490.
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Abigail E. Niesen & Maury L. Hull. (2023) State of the Art in Radiostereometric Analysis for Tibial Baseplate Migration and Future Research Directions. Journal of Biomechanical Engineering 145:12.
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Luigi Molfetta, Andrea Casabella, Sergio Rosini, Gianantonio Saviola & Augusto Palermo. (2022) Role of the Osteochondral Unit in the Pathogenesis of Osteoarthritis: Focus on the Potential Use of Clodronate. Current Rheumatology Reviews 18:1, pages 2-11.
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Jukka Kiuttu, Petri Lehenkari, Hannu-Ville Leskelä, Olli Yrjämä, Pasi Ohtonen & Maarit Valkealahti. (2021) Intra-operative Clodronate Rinsing Improves the Integration of the Femoral Stem in a Prospective, Double-blinded, Randomized, Placebo-controlled Clinical RSA-study. The Open Orthopaedics Journal 15:1, pages 1-12.
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Jahan Abtahi, Benjamin Klintström & Eva Klintström. (2021) Ibandronate Reduces the Surface Bone Resorption of Mandibular Bone Grafts: A Randomized Trial With Internal Controls. JBMR Plus 5:3.
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Mohammed Mahri, Nicole Shen, Francisco Berrizbeitia, Rania Rodan, Ammar Daer, Matthew Faigan, Doaa Taqi, Kevin Yang Wu, Motahareh Ahmadi, Maxime Ducret, Elham Emami & Faleh Tamimi. (2021) Osseointegration Pharmacology: A Systematic Mapping Using Artificial Intelligence. Acta Biomaterialia 119, pages 284-302.
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Gianantonio Saviola, Paolo Ferrari, Ernesto Niccolò, Andrea Casabella, Francesco Ghellere, Sonia Bonazzi, Abdi-Ali Lul, Laura Comini & Luigi Molfetta. (2020) Use of clodronate for painful knee prosthesis in osteoarthritis patients: a 6-month pilot study. Minerva Medica 111:6.
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J. Mark Wilkinson. (2020) The use of bisphosphonates to meet orthopaedic challenges. Bone 137, pages 115443.
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Siwar Mosbahi, Hassane Oudadesse, Claire Roiland, Bertrand Lefeuvre, Lotfi Slimani & Hassib Keskes. (2019) Risedronate Effects on the In Vivo Bioactive Glass Behavior: Nuclear Magnetic Resonance and Histopathological Studies. BioMed Research International 2019, pages 1-16.
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Benjamin A. McArthur, Ryan Scully, F. Patrick Ross, Mathias P. G. Bostrom & Anna Falghren. (2018) Mechanically Induced Periprosthetic Osteolysis: A Systematic Review. HSS Journal ® 15:3, pages 286-296.
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Liqing Yang. (2018) The efficiency of risedronate in reducing bone resorption after total hip arthroplasty: a meta-analysis of randomized control trials at a minimum of 6 months’ follow-up. Journal of Orthopaedic Surgery and Research 13:1.
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Rasmus Cleemann, Joan E. Bechtold, Mette Sorensen, Kjeld Soballe & Jorgen Baas. (2018) Dose-Dependent Resorption of Allograft by rhBMP-2 Uncompensated by New Bone Formation—A Canine Study With Implants and Zoledronate. The Journal of Arthroplasty 33:4, pages 1215-1221.e1.
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Ralf Skripitz, Andreas Roth, Klaus M. Peters, Gerald Zimmermann, Hans Goost, Thomas Randau, Marcus Jäger, Ulrich Nöth & Marcel Haversath. 2018. Fortbildung Osteologie 4. Fortbildung Osteologie 4 33 69 .
Sebastian S. Mukka, Göran N. Andersson, Kjell R. Hultenby, Olof G. Sköldenberg, Joakim P. Nordahl & Thomas M. Eisler. (2017) Osteoclasts in Periprosthetic Osteolysis: The Charnley Arthroplasty Revisited. The Journal of Arthroplasty 32:10, pages 3219-3227.
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J. Abtahi, G. Henefalk & P. Aspenberg. (2016) Randomised trial of bisphosphonate-coated dental implants: Radiographic follow-up after five years of loading. International Journal of Oral and Maxillofacial Surgery 45:12, pages 1564-1569.
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Ashir Ejaz, Anders C. Laursen, Thomas Jakobsen, Sten Rasmussen, Poul Torben Nielsen & Mogens B. Laursen. (2015) Absence of a Tourniquet Does Not Affect Fixation of Cemented TKA: A Randomized RSA Study of 70 Patients. The Journal of Arthroplasty 30:12, pages 2128-2132.
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R. Skripitz, A. Kurth & A. Roth. (2015) Medikamentöse Verbesserung der ImplantateinheilungSupportive drugs for improved implant healing. Der Orthopäde 44:9, pages 703-709.
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A. V. J. JaromaT. A. SoininvaaraH. Kröger. (2015) Effect of one-year post-operative alendronate treatment on periprosthetic bone after total knee arthroplasty. The Bone & Joint Journal 97-B:3, pages 337-345.
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D. Wang, G. Wu, X. Lin & Y. Liu. 2015. Surface Coating and Modification of Metallic Biomaterials. Surface Coating and Modification of Metallic Biomaterials 345 358 .
Joerg Arnoldi, Antoine Alves & Philip Procter. (2014) Early tissue responses to zoledronate, locally delivered by bone screw, into a compromised cancellous bone site: a pilot study. BMC Musculoskeletal Disorders 15:1.
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N. M. C. Mathijssen, P. Buma & G. Hannink. (2013) Combining bisphosphonates with allograft bone for implant fixation. Cell and Tissue Banking 15:3, pages 329-336.
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Łukasz Matuszewski, Grażyna Olchowik, Tomasz Mazurkiewicz, Bartłomiej Kowalczyk, Agata Zdrojewska, Anna Matuszewska, Andrzej Ciszewski, Małgorzata Gospodarek & Iwona Morawik. (2013) Biomechanical parameters of the BP-enriched bone cement. European Journal of Orthopaedic Surgery & Traumatology 24:4, pages 435-441.
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Mats Molt, Andreas Harsten & Sören Toksvig-Larsen. (2014) The effect of tourniquet use on fixation quality in cemented total knee arthroplasty a prospective randomized clinical controlled RSA trial. The Knee 21:2, pages 396-401.
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Tuuli M. Saari, Georgios Digas & Johan N. Kärrholm. (2018) Risedronate does not Enhance Fixation or BMD in Revision Cups: Randomised Study with Three Years follow-up. HIP International 24:1, pages 49-55.
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Lars Rasmusson & Jahan Abtahi. (2014) Bisphosphonate Associated Osteonecrosis of the Jaw: An Update on Pathophysiology, Risk Factors, and Treatment. International Journal of Dentistry 2014, pages 1-9.
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John Irish, Amarjit S. Virdi, Kotaro Sena, Margaret A. McNulty & Dale R. Sumner. (2012) Implant placement increases bone remodeling transiently in a rat model. Journal of Orthopaedic Research 31:5, pages 800-806.
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M. MoltP. LjungS. Toksvig-Larsen. (2012) Does a new knee design perform as well as the design it replaces?. Bone & Joint Research 1:12, pages 315-323.
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Nina MC Mathijssen, Gerjon Hannink, Peter Pilot, B Wim Schreurs, Rolf M Bloem & Pieter Buma. (2012) Impregnation of bone chips with alendronate and cefazolin, combined with demineralized bone matrix: a bone chamber study in goats. BMC Musculoskeletal Disorders 13:1.
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Juan Pablo CattaliniAldo R. BoccacciniSilvia LucangioliViviana Mouriño. (2012) Bisphosphonate-Based Strategies for Bone Tissue Engineering and Orthopedic Implants. Tissue Engineering Part B: Reviews 18:5, pages 323-340.
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Kyriakos A Papavasiliou, Aggeliki Nikopoulou, Eustathios I Kenanidis, Michael E Potoupnis, Margaritis J Kyrkos, Fares E Sayegh & George A Kapetanos. (2012) Serum Intact-Parathyroid Hormone Level following Total Knee Arthroplasty. Journal of Orthopaedic Surgery 20:1, pages 27-31.
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Olof Gustaf Sköldenberg, Mats Olof Salemyr, Henrik Stefan Bodén, Torbjörn Efraim Ahl & Per Yngve Adolphson. (2011) The Effect of Weekly Risedronate on Periprosthetic Bone Resorption Following Total Hip Arthroplasty. Journal of Bone and Joint Surgery 93:20, pages 1857-1864.
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J. Mark Wilkinson & David G. Little. (2011) Bisphosphonates in orthopedic applications. Bone 49:1, pages 95-102.
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Kimberly McKenzie, J. Dennis Bobyn, Jacintha Roberts, Dorota Karabasz & Michael Tanzer. (2010) Bisphosphonate Remains Highly Localized After Elution From Porous Implants. Clinical Orthopaedics and Related Research? 469:2, pages 514-522.
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Eustathios I Kenanidis, Michael E Potoupnis, Kyriakos A Papavasilioul, Fares E Sayegh, George E Petsatodis & George A Kapetanos. (2010) Serum Levels of Bone Turnover Markers following Total Joint Arthroplasty. Journal of Orthopaedic Surgery 18:3, pages 290-295.
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Theis M. Thillemann, Alma B. Pedersen, Frank Mehnert, Søren P. Johnsen & Kjeld Søballe. (2010) Postoperative use of bisphosphonates and risk of revision after primary total hip arthroplasty: A nationwide population-based study. Bone 46:4, pages 946-951.
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Qingyun Xue, Haisheng Li, Xuenong Zou, Michel Dalstra, Martin Lind, Finn B. Christensen & Cody Bünger. (2009) Alendronate treatment improves bone–pedicle screw interface fixation in posterior lateral spine fusion: An experimental study in a porcine model. International Orthopaedics 34:3, pages 447-451.
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Kyriakos A Papavasiliou, Eustathios I Kenanidis, Michael E Potoupnis, Ioannis K Sarris, John M Kirkos & George A Kapetanos. (2009) Incidence of Secondary Hyperparathyroidism among Postmenopausal Women with End-Stage Knee Osteoarthritis. Journal of Orthopaedic Surgery 17:3, pages 310-312.
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Svetlana Semenovna Rodionova, T N Turgumbaev, S S Rodionova & T N Turgumbaev. (2009) Use of Alendronate in Postoperative Period for Prevention of Hip Implant Aseptic Instability. N.N. Priorov Journal of Traumatology and Orthopedics 16:3, pages 36-44.
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Sanjeev Kakar, David Little & Thomas A Einhorn. (2009) Can We Improve Fixation and Outcomes in the Treatment of Femoral Neck Fractures? The Use of Pharmaceuticals. Journal of Orthopaedic Trauma 23:6, pages 413-421.
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Ulrik Hansson, Leif Ryd & S?ren Toksvig-Larsen. (2008) A randomised RSA study of Peri-Apatite? HA coating of a total knee prosthesis. The Knee 15:3, pages 211-216.
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K. Wermelin, F. Suska, P. Tengvall, P. Thomsen & P. Aspenberg. (2008) Stainless steel screws coated with bisphosphonates gave stronger fixation and more surrounding bone. Histomorphometry in rats. Bone 42:2, pages 365-371.
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Adam M. Kaufman, Claude I. Alabre, Harry E. Rubash & Arun S. Shanbhag. (2007) Human macrophage response to UHMWPE, TiAlV, CoCr, and alumina particles: Analysis of multiple cytokines using protein arrays. Journal of Biomedical Materials Research Part A 84A:2, pages 464-474.
Crossref
L RYD. 2008. Joint Replacement Technology. Joint Replacement Technology 286 311 .
Saba Haque, Ihtesham Rehman & Jawwad A. Darr. (2007) Synthesis and Characterization of Grafted Nanohydroxyapatites Using Functionalized Surface Agents. Langmuir 23:12, pages 6671-6676.
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Crossref
Jonathan M. Labovitz & Kate Revill. (2007) Osteoporosis: Pathogenesis, New Therapies and Surgical Implications. Clinics in Podiatric Medicine and Surgery 24:2, pages 311-332.
Crossref
Thomas Jakobsen, Søren Kold, Joan. E. Bechtold, Brian Elmengaard & Kjeld Søballe. (2006) Local alendronate increases fixation of implants inserted with bone compaction: 12‐week canine study. Journal of Orthopaedic Research 25:4, pages 432-441.
Crossref
C. Eberhardt, B. Habermann & A.A. Kurth. (2007) Anwendungsmöglichkeiten der Bisphosphonate in der EndoprothetikThe use of bisphosphonates in arthroplasty. Der Orthopäde 36:2, pages 141-145.
Crossref
Reiner Bartl, Bertha Frisch, Emmo von Tresckow & Christoph Bartl. 2007. Bisphosphonates in Medical Practice. Bisphosphonates in Medical Practice 235 258 .
Jörgen Åstrand, Anna Kajsa Harding, Per Aspenberg & Magnus Tägil. (2006) Systemic zoledronate treatment both prevents resorption of allograft bone and increases the retention of new formed bone during revascularization and remodelling. A bone chamber study in rats. BMC Musculoskeletal Disorders 7:1.
Crossref
A H Glassman, J D Bobyn & M Tanzer. (2006) New Femoral Designs. Clinical Orthopaedics & Related Research 453, pages 64-74.
Crossref
Johan K??rrholm, Richie H S Gill & Edward R Valstar. (2006) The History and Future of Radiostereometric Analysis. Clinical Orthopaedics and Related Research 448, pages 10-21.
Crossref
Arun S. Shanbhag. (2006) Use of Bisphosphonates to Improve the Durability of Total Joint Replacements. Journal of the American Academy of Orthopaedic Surgeons 14:4, pages 215-225.
Crossref
Thomas Jakobsen, Søren Kold, Joan E Bechtold, Brian Elmengaard & Kjeld Søballe. (2006) Effect of Topical Alendronate Treatment on Fixation of Implants Inserted with Bone Compaction. Clinical Orthopaedics & Related Research 444, pages 229-234.
Crossref
Maarit Kellinsalmi, Hannu Mönkkönen, Jukka Mönkkönen, Hannu‐Ville Leskelä, Vilhelmiina Parikka, Martti Hämäläinen & Petri Lehenkari. (2005) In vitro Comparison of Clodronate, Pamidronate and Zoledronic Acid Effects on Rat Osteoclasts and Human Stem Cell‐Derived Osteoblasts . Basic & Clinical Pharmacology & Toxicology 97:6, pages 382-391.
Crossref
Michael Tanzer, Dorota Karabasz, Jan J Krygier, Robert Cohen & J Dennis Bobyn. (2005) THE OTTO AUFRANC AWARD: Bone Augmentation around and within Porous Implants by Local Bisphosphonate Elution. Clinical Orthopaedics and Related Research 441:&NA;, pages 30-39.
Crossref
Per Aspenberg. 2005. Joint Replacement and Bone Resorption. Joint Replacement and Bone Resorption 399 411 .
J Bobyn, M Tanzer & A Glassman. 2005. Joint Replacement and Bone Resorption. Joint Replacement and Bone Resorption 375 397 .
MOHIT BHANDARI, SOHAIL BAJAMMAL, GORDON H. GUYATT, LAUREN GRIFFITH, JASON W. BUSSE, HOLGER SCHÜNEMANN & THOMAS A. EINHORN. (2005) EFFECT OF BISPHOSPHONATES ON PERIPROSTHETIC BONE MINERAL DENSITY AFTER TOTAL JOINT ARTHROPLASTY. The Journal of Bone and Joint Surgery-American Volume 87:2, pages 293-301.
Crossref
B. Peter, D.P. Pioletti, S. Laïb, B. Bujoli, P. Pilet, P. Janvier, J. Guicheux, P.-Y. Zambelli, J.-M. Bouler & O. Gauthier. (2005) Calcium phosphate drug delivery system: influence of local zoledronate release on bone implant osteointegration. Bone 36:1, pages 52-60.
Crossref
Beatrice Sommer, Rolf Felix, Christoph Sprecher, Michael Leunig, Reinhold Ganz & Willy Hofstetter. (2004) Wear particles and surface topographies are modulators of osteoclastogenesis in vitro . Journal of Biomedical Materials Research Part A 72A:1, pages 67-76.
Crossref
Björn Skoglund, Jonas Holmertz & Per Aspenberg. (2006) Systemic and local ibandronate enhance screw fixation. Journal of Orthopaedic Research 22:5, pages 1108-1113.
Crossref
Jörgen Åstrand & Per Aspenberg. (2006) Topical, single dose bisphosphonate treatment reduced bone resorption in a rat model for prosthetic loosening. Journal of Orthopaedic Research 22:2, pages 244-249.
Crossref
Reiner Bartl & Christoph BartlReiner Bartl & Christoph Bartl. 2004. Osteoporose-Manual. Osteoporose-Manual 149 198 .
J??rgen ??strand, Ralf Skripitz, Bj??rn Skoglund & Per Aspenberg. (2003) A Rat Model for Testing Pharmacologic Treatments of Pressure-Related Bone Loss. Clinical Orthopaedics and Related Research 409, pages 296-305.
Crossref

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