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Hemoglobin
international journal for hemoglobin research
Volume 32, 2008 - Issue 4
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Review Article

Unstable and Thalassemic α Chain Hemoglobin Variants: A Cause of Hb H Disease and Thalassemia Intermedia

Henri Wajcman INSERM U841, 94010, Créteil, FranceCorrespondence[email protected]
,
Jan Traeger-Synodinos Laboratory of Medical Genetics, University of Athens, “Aghia Sophia” Children's Hospital, Athens, Greece
,
Ioannis Papassotiriou Department of Clinical Biochemistry, “Aghia Sophia” Children's Hospital, Athens, Greece
,
Piero C. Giordano Departments of Human and Clinical Genetics and The Hemoglobinopathies Laboratory, Leiden University Medical Center, Leiden, The Netherlands
,
Cornelis L. Harteveld Departments of Human and Clinical Genetics and The Hemoglobinopathies Laboratory, Leiden University Medical Center, Leiden, The Netherlands
,
Véronique Baudin-Creuza INSERM U779, 94275 Le Kremlin-Bicêtre Cedex, France
&
John Old National Haemoglobinopathy Reference Laboratory, Oxford Haemophilia Centre, Churchill Hospital, Oxford, United Kingdom
 show all
Pages 327-349 | Received 08 Jan 2008, Accepted 03 Feb 2008, Published online: 07 Jul 2009

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Can Liao, Jian-Ying Zhou, Xing-Mei Xie, Ying-Na Liu, Li-He Chen & Dong-Zhi Li. (2011) Identification of a New α Chain Variant at Codons 22–25 (–9 nts) Using the Sebia Capillarys 2 Electrophoresis System. Hemoglobin 35:2, pages 166-170.
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Inusha Panigrahi, Ram K. Marwaha & Ketan Kulkarni. (2009) The expanding spectrum of thalassemia intermedia. Hematology 14:6, pages 311-314.
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Philippe Joly, Philippe Lacan, Martine Bererd, Caroline Garcia, Isabelle Zanella-Cleon, Michel Becchi, Martine Aubry, Nicole Couprie & Alain Francina. (2009) Description of Two New α Variants: Hb Canuts [α85(F6)Asp→His (α1)] and Hb Ambroise Pare [α117(GH5)Phe→Ile (α2)]; Two New β Variants: Hb Beaujolais [β84(EF8)Thr→Asn] and Hb Monplaisir [β147 (Tyr-Lys-Leu-Ala-Phe-Phe-Leu-Leu-Ser-Asn-Phe-Tyr-158-COOH)] and One New δ Variant: Hb A2-North Africa [δ59(E3)Lys→Met]. Hemoglobin 33:3-4, pages 196-205.
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