5,440
Views
321
CrossRef citations to date
0
Altmetric
Review Article

Sirtuins: The ‘magnificent seven’, function, metabolism and longevity

, , , , &
Pages 335-345 | Published online: 08 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (17)

Ying-Nan Ni, Liang Kong, Xue-Tao Li, Hong-He Xiao, Yu-Tong Wu, Xi-Cai Liang, Ying Lin, Wan-Yi Li, Yan Deng, Yan Li, Yue Shi, Lan Cheng, Hong-Yan Li, Rui-Jun Ju & Jing-Xian Yang. (2021) Multifunctional osthole liposomes and brain targeting functionality with potential applications in a mouse model of Alzheimer’s disease. Journal of Liposome Research 31:3, pages 267-278.
Read now
Xiaolin Wang, Yuanqiang Dai, Xiaoxiu Zhang, Ke Pan, Yu Deng, Jiafeng Wang & Tao Xu. (2021) CXCL6 regulates cell permeability, proliferation, and apoptosis after ischemia–reperfusion injury by modulating Sirt3 expression via AKT/FOXO3a activation. Cancer Biology & Therapy 22:1, pages 30-39.
Read now
Yu-Ting Wu, Kun-Ting Chi, Yueh-Wen Lan, Jui-Chi Chan, Yi-Shing Ma & Yau-Huei Wei. (2018) Depletion of Sirt3 leads to the impairment of adipogenic differentiation and insulin resistance via interfering mitochondrial function of adipose-derived human mesenchymal stem cells. Free Radical Research 52:11-12, pages 1398-1415.
Read now
Somayyeh Asghari, Mohammad Asghari-Jafarabadi, Mohammad-Hossein Somi, Seyed-Mostafa Ghavami & Maryam Rafraf. (2018) Comparison of Calorie-Restricted Diet and Resveratrol Supplementation on Anthropometric Indices, Metabolic Parameters, and Serum Sirtuin-1 Levels in Patients With Nonalcoholic Fatty Liver Disease: A Randomized Controlled Clinical Trial. Journal of the American College of Nutrition 37:3, pages 223-233.
Read now
Abdul Hameed, Mariya Al-Rashida, Rima D. Alharthy, Maliha Uroos, Ehsan Ullah Mughal, Syed Abid Ali & Khalid Mohammed Khan. (2017) Small molecules as activators in medicinal chemistry (2000–2016). Expert Opinion on Therapeutic Patents 27:10, pages 1089-1110.
Read now
P.F. Surai & V.I. Fisinin. (2016) Vitagenes in poultry production: Part 3. Vitagene concept development. World's Poultry Science Journal 72:4, pages 793-804.
Read now
Cristina Carvalho, Sónia C Correia, Susana Cardoso, Ana I Plácido, Emanuel Candeias, Ana I Duarte & Paula I Moreira. (2015) The role of mitochondrial disturbances in Alzheimer, Parkinson and Huntington diseases. Expert Review of Neurotherapeutics 15:8, pages 867-884.
Read now
Takeshi Kurose, Takanori Hyo, Daisuke Yabe & Yutaka Seino. (2014) The role of chronobiology and circadian rhythms in type 2 diabetes mellitus: implications for management of diabetes. ChronoPhysiology and Therapy 4, pages 41-49.
Read now
Ayesha Murshid, Takanori Eguchi & Stuart K. Calderwood. (2013) Stress proteins in aging and life span. International Journal of Hyperthermia 29:5, pages 442-447.
Read now
Nassim Dali-Youcef, Mustapha Mecili, Roméo Ricci & Emmanuel Andrès. (2013) Metabolic inflammation: Connecting obesity and insulin resistance. Annals of Medicine 45:3, pages 242-253.
Read now
Cameron B Williams & Brendon J Gurd. (2012) Skeletal muscle SIRT1 and the genetics of metabolic health: therapeutic activation by pharmaceuticals and exercise. The Application of Clinical Genetics 5, pages 81-91.
Read now
Martin V. Bennetzen, Guillermo Mariño, Dennis Pultz, Eugenia Morselli, Nils J. Færgeman, Guido Kroemer & Jens S. Andersen. (2012) Phosphoproteomic analysis of cells treated with longevity-related autophagy inducers. Cell Cycle 11:9, pages 1827-1840.
Read now
Hassina Massudi, Ross Grant, Gilles J Guillemin & Nady Braidy. (2012) NAD+ metabolism and oxidative stress: the golden nucleotide on a crown of thorns. Redox Report 17:1, pages 28-46.
Read now
Nilanjan Ghosh, Rituparna Ghosh & Subhash C. Mandal. (2011) Antioxidant protection: A promising therapeutic intervention in neurodegenerative disease. Free Radical Research 45:8, pages 888-905.
Read now
Urs Albrecht. (2010) Circadian clocks in mood-related behaviors. Annals of Medicine 42:4, pages 241-251.
Read now
Philip Hallenborg, Søren Feddersen, Lise Madsen & Karsten Kristiansen. (2009) The tumor suppressors pRB and p53 as regulators of adipocyte differentiation and function. Expert Opinion on Therapeutic Targets 13:2, pages 235-246.
Read now

Articles from other publishers (304)

Arnold Bhebhe, Shabana S. Meyering & Sabita N. Saldanha. 2024. Epigenetics in Human Disease. Epigenetics in Human Disease 207 257 .
John S. Harrington, Stefan W. Ryter, Maria Plataki, David R. Price & Augustine M. K. Choi. (2023) Mitochondria in health, disease, and aging. Physiological Reviews 103:4, pages 2349-2422.
Crossref
Jennifer N. Baumgartner, Bramaramba Kowtha, Gabriela Riscuta, Anil Wali & Yunling Gao. (2023) Molecular underpinnings of physical activity and resilience: A brief overview of the state‐of‐science and research design needs. Stress and Health.
Crossref
Sara E. Hamza, Sara A. Wahdan & Ebtehal El‐Demerdash. (2023) Effect of phylloquinone on indomethacin‐induced gastric ulceration in rats: Role of SIRT ‐1 . Clinical and Experimental Pharmacology and Physiology 50:5, pages 369-379.
Crossref
Alison F Ermisch, Katie L Bidne, Scott G Kurz, Kerri A Bochantin & Jennifer R Wood. (2023) Ovarian inflammation mediated by Toll-like receptor 4 increased transcripts of maternal effect genes and decreased embryo development. Biology of Reproduction 108:3, pages 423-436.
Crossref
Michele Aventaggiato, Federica Barreca, Laura Vitiello, Simone Vespa, Sergio Valente, Dante Rotili, Antonello Mai, Lavinia Vittoria Lotti, Luigi Sansone, Matteo A. Russo, Mariano Bizzarri, Elisabetta Ferretti & Marco Tafani. (2023) Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery. Cells 12:5, pages 691.
Crossref
Xiaofang Guo, Xiwen Xiong, Lijun Zhao, Genshen Zhong & Xiaofei Zhu. 2023. Anti-Aging Pharmacology. Anti-Aging Pharmacology 305 327 .
Neha Rawal, Anupam Mittal & Madhu Khullar. 2023. The Renin Angiotensin System in Cardiovascular Disease. The Renin Angiotensin System in Cardiovascular Disease 275 289 .
Patrycja Ziętara, Marta Dziewięcka & Maria Augustyniak. (2022) Why Is Longevity Still a Scientific Mystery? Sirtuins—Past, Present and Future. International Journal of Molecular Sciences 24:1, pages 728.
Crossref
Charles Brenner. (2022) Sirtuins are not conserved longevity genes. Life Metabolism 1:2, pages 122-133.
Crossref
Su-Youn Cho & Hee-Tae Roh. (2022) Effects of Exercise Training on Neurotrophic Factors and Blood–Brain Barrier Permeability in Young-Old and Old-Old Women. International Journal of Environmental Research and Public Health 19:24, pages 16896.
Crossref
Seong-Gon Kim. (2022) 4-Hexylresorcinol: pharmacologic chaperone and its application for wound healing. Maxillofacial Plastic and Reconstructive Surgery 44:1.
Crossref
Elena Sidorova-Darmos, Merrick S. Fallah, Richard Logan, Cheng Yu Lin & James H. Eubanks. (2022) Mitochondrial brain proteome acetylation levels and behavioural responsiveness to amphetamine are altered in mice lacking Sirt3. Frontiers in Physiology 13.
Crossref
Tiziana Schioppa, Hoang Oanh Nguyen, Laura Tiberio, Francesca Sozio, Carolina Gaudenzi, Mauro Passari, Annalisa Del Prete, Daniela Bosisio & Valentina Salvi. (2022) Inhibition of Class I Histone Deacetylase Activity Blocks the Induction of TNFAIP3 Both Directly and Indirectly via the Suppression of Endogenous TNF-α. International Journal of Molecular Sciences 23:17, pages 9752.
Crossref
Dan Zhou, Lanfang Zhang, Liwei Mao, Jingyu Cao & Jiaqiang Gao. (2022) Biological Mechanism on SIRT1/NLRP3/IL-18 Signaling Pathway of Acupuncture for Treatment of Ischemic Stroke with Center Poststroke Pain. Computational Intelligence and Neuroscience 2022, pages 1-10.
Crossref
Borut Poljšak, Vito Kovač & Irina Milisav. (2022) Current Uncertainties and Future Challenges Regarding NAD+ Boosting Strategies. Antioxidants 11:9, pages 1637.
Crossref
Eun-Joo Lee, Myeong-Mi Lee, SunYoung Park & Kyu-Shik Jeong. (2022) Sirt2 positively regulates muscle regeneration after Notexin-induced muscle injury. Experimental and Molecular Pathology 127, pages 104798.
Crossref
Michele Aventaggiato, Federica Barreca, Luigi Sansone, Laura Pellegrini, Matteo A. Russo, Marco Cordani & Marco Tafani. (2022) Sirtuins and Hypoxia in EMT Control. Pharmaceuticals 15:6, pages 737.
Crossref
Muhammad Usman Arif, Muhammad Kashif Iqbal Khan, Sana Riaz, Akmal Nazir, Abid Aslam Maan, Usman Amin, Farhan Saeed & Muhammad Afzaal. (2022) Role of fruits in aging and age-related disorders. Experimental Gerontology 162, pages 111763.
Crossref
Shalie Malik, James Stokes III, Upender Manne, Rajesh Singh & Manoj K. Mishra. (2022) Understanding the significance of biological clock and its impact on cancer incidence. Cancer Letters 527, pages 80-94.
Crossref
Hongsheng Fang, Yizhou Huang, Yang Luo, Jiayin Tang, Minhao Yu, Yan Zhang & Ming Zhong. (2022) SIRT1 induces the accumulation of TAMs at colorectal cancer tumor sites via the CXCR4/CXCL12 axis. Cellular Immunology 371, pages 104458.
Crossref
Julia Brenmoehl, Christina Walz, Caroline Caffier, Elli Brosig, Michael Walz, Daniela Ohde, Nares Trakooljul, Martina Langhammer, Siriluck Ponsuksili, Klaus Wimmers, Uwe K. Zettl & Andreas Hoeflich. (2021) Central Suppression of the GH/IGF Axis and Abrogation of Exercise-Related mTORC1/2 Activation in the Muscle of Phenotype-Selected Male Marathon Mice (DUhTP). Cells 10:12, pages 3418.
Crossref
Alyson M. Curry, Ian Cohen, Song Zheng, Jessica Wohlfahrt, Dawanna S. White, Dickson Donu & Yana Cen. (2021) Profiling sirtuin activity using Copper-free click chemistry. Bioorganic Chemistry 117, pages 105413.
Crossref
Aliki-Alexandra Papageorgiou, Andreas Goutas, Varvara Trachana & Aspasia Tsezou. (2021) Dual Role of SIRT1 in Autophagy and Lipid Metabolism Regulation in Osteoarthritic Chondrocytes. Medicina 57:11, pages 1203.
Crossref
Min Kyung Song, Yoon Ju Kim, Sang Hoon Kim, Seung Geun Yeo & Youn-Jung Kim. (2021) Environmental enrichment modulates silent information regulator 1 (SIRT1) activity to attenuate central presbycusis in a rat model of normal aging. Experimental Gerontology 155, pages 111552.
Crossref
Md Jamal Uddin, Mithila Farjana, Akhi Moni, Khandkar Shaharina Hossain, Md. Abdul Hannan & Hunjoo Ha. (2021) Prospective Pharmacological Potential of Resveratrol in Delaying Kidney Aging. International Journal of Molecular Sciences 22:15, pages 8258.
Crossref
Rihan Hai, Liuer He, Guang Shu & Gang Yin. (2021) Characterization of Histone Deacetylase Mechanisms in Cancer Development. Frontiers in Oncology 11.
Crossref
Nora Junker & Toni I. Gossmann. (2021) Adaptation-Driven Evolution of Sirtuin 1 (SIRT1), a Key Regulator of Metabolism and Aging, in Marmot Species. Frontiers in Ecology and Evolution 9.
Crossref
Ji H. Kang, Ji E. Park, Jason Dagoon, Stewart W. C. Masson, Troy L. Merry, Shannon N. Bremner, Jessica R. Dent & Simon Schenk. (2021) Sirtuin 1 is not required for contraction-stimulated glucose uptake in mouse skeletal muscle. Journal of Applied Physiology 130:6, pages 1893-1902.
Crossref
Michele Aventaggiato, Enza Vernucci, Federica Barreca, Matteo A. Russo & Marco Tafani. (2021) Sirtuins' control of autophagy and mitophagy in cancer. Pharmacology & Therapeutics 221, pages 107748.
Crossref
Jan Frohlich, George N. Chaldakov & Manlio Vinciguerra. (2021) Cardio- and Neurometabolic Adipobiology: Consequences and Implications for Therapy. International Journal of Molecular Sciences 22:8, pages 4137.
Crossref
Peter F. Surai, Ivan I. Kochish & Vladimir I. Fisinin. 2021. Sirtuin Biology in Medicine. Sirtuin Biology in Medicine 353 372 .
George N. Chaldakov, Luigi Aloe, Gorana Rancic, Rouzha Z. Pancheva, Marcia Hiriart, Marco Fiore & Stanislav Yanev. 2021. Cellular and Biochemical Mechanisms of Obesity. Cellular and Biochemical Mechanisms of Obesity 297 312 .
Rosa María Tordera & María Cortés-Erice. 2021. Reviews of Physiology, Biochemistry and Pharmacology. Reviews of Physiology, Biochemistry and Pharmacology 1 47 .
Alyson M. Curry, Elizabeth Barton, Wenjia Kang, Daniel V. Mongeluzi & Yana Cen. (2020) Development of Second Generation Activity-Based Chemical Probes for Sirtuins. Molecules 26:1, pages 11.
Crossref
Borut Poljsak, Vito Kovač & Irina Milisav. (2020) Healthy Lifestyle Recommendations: Do the Beneficial Effects Originate from NAD+ Amount at the Cellular Level?. Oxidative Medicine and Cellular Longevity 2020, pages 1-12.
Crossref
Peter F. Surai. 2020. Vitagenes in avian biology and poultry health. Vitagenes in avian biology and poultry health 259 296 .
Maria V. Deligiorgi, Charis Liapi & Dimitrios T. Trafalis. (2020) How Far Are We from Prescribing Fasting as Anticancer Medicine?. International Journal of Molecular Sciences 21:23, pages 9175.
Crossref
Zi-Ning Kao, Chun-Hung Liu, Wang-Jing Liu, Ramya Kumar, Jiann-Horng Leu & Han-Ching Wang. (2020) Shrimp SIRT1 activates of the WSSV IE1 promoter independently of the NF-κB binding site. Fish & Shellfish Immunology 106, pages 910-919.
Crossref
Marwa Elamin, David N. Ruskin, Paola Sacchetti & Susan A. Masino. (2020) A unifying mechanism of ketogenic diet action: The multiple roles of nicotinamide adenine dinucleotide. Epilepsy Research 167, pages 106469.
Crossref
Déborah Cardoso & Antoine Muchir. (2020) Need for NAD+: Focus on Striated Muscle Laminopathies. Cells 9:10, pages 2248.
Crossref
Chin-Chang Chen, Zi-Yu Chang, Fuu-Jen Tsai & Shih-Yin Chen. (2020) Resveratrol Pretreatment Ameliorates Concanavalin A-Induced Advanced Renal Glomerulosclerosis in Aged Mice through Upregulation of Sirtuin 1-Mediated Klotho Expression. International Journal of Molecular Sciences 21:18, pages 6766.
Crossref
Ji-Duo Shen, Yue-Wen Zhang, Bao-Ying Wang, Li Bai, Shuai-Fei Lu, Lei-Lei Zhu, Ming Bai, Yu-Cheng Li & Er-Ping Xu. (2020) Effects of resveratrol on the levels of ATP, 5-HT and GAP-43 in the hippocampus of mice exposed to chronic unpredictable mild stress. Neuroscience Letters 735, pages 135232.
Crossref
Li Li Ji, Dongwook Yeo, Chounghun Kang & Tianou Zhang. (2020) The role of mitochondria in redox signaling of muscle homeostasis. Journal of Sport and Health Science 9:5, pages 386-393.
Crossref
Zsolt Radak, Katsuhiko Suzuki, Aniko Posa, Zita Petrovszky, Erika Koltai & Istvan Boldogh. (2020) The systemic role of SIRT1 in exercise mediated adaptation. Redox Biology 35, pages 101467.
Crossref
Mario Mehmel, Nina Jovanović & Urs Spitz. (2020) Nicotinamide Riboside—The Current State of Research and Therapeutic Uses. Nutrients 12:6, pages 1616.
Crossref
Tanira Matutino Bastos, Milena Botelho Pereira Soares, Caio Haddad Franco, Laura Alcântara, Lorenzo Antonini, Manuela Sabatino, Nicola Mautone, Lucio Holanda Freitas-Junior, Carolina Borsoi Moraes, Rino Ragno, Dante Rotili, Sergio Schenkman, Antonello Mai & Nilmar Silvio Moretti. (2020) Identification of Inhibitors to Trypanosoma cruzi Sirtuins Based on Compounds Developed to Human Enzymes. International Journal of Molecular Sciences 21:10, pages 3659.
Crossref
Brígida A.A. Spagnol, Tathiana F.S. Antunes, Oeber F. Quadros, A. Alberto R. Fernandes & Patricia M.B. Fernandes. (2020) Differences in gene modulation in Saccharomyces cerevisiae indicate that maturity plays an important role in the high hydrostatic pressure stress response and resistance. Fungal Biology 124:5, pages 440-446.
Crossref
Mouhamed Idrissou, Anna Sanchez, Frédérique Penault-Llorca, Yves-Jean Bignon & Dominique Bernard-Gallon. (2020) Epi-drugs as triple-negative breast cancer treatment. Epigenomics 12:8, pages 725-742.
Crossref
Menizibeya O. Welcome. (2020) The bitterness of genitourinary infections: Properties, ligands of genitourinary bitter taste receptors and mechanisms linking taste sensing to inflammatory processes in the genitourinary tract. European Journal of Obstetrics & Gynecology and Reproductive Biology 247, pages 101-110.
Crossref
Ambra A. Grolla, Riccardo Miggiano, Daniele Di Marino, Michele Bianchi, Alessandro Gori, Giuseppe Orsomando, Federica Gaudino, Ubaldina Galli, Erika Del Grosso, Francesca Mazzola, Carlo Angeletti, Martina Guarneri, Simone Torretta, Marta Calabrò, Sara Boumya, Xiaorui Fan, Giorgia Colombo, Cristina Travelli, Francesca Rocchio, Eleonora Aronica, James A. Wohlschlegel, Silvia Deaglio, Menico Rizzi, Armando A. Genazzani & Silvia Garavaglia. (2020) A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus. Journal of Biological Chemistry 295:11, pages 3635-3651.
Crossref
Jieting Liu, Shali Chen, Saumik Biswas, Niharika Nagrani, Yanhui Chu, Subrata Chakrabarti & Biao Feng. (2020) Glucose‐induced oxidative stress and accelerated aging in endothelial cells are mediated by the depletion of mitochondrial SIRTs. Physiological Reports 8:3.
Crossref
Carmela Farias da Silva Tagliari, Cáren Nunes de Oliveira, Greice Meyer Vogel, Patrícia Baptista da Silva, Rafael Linden, Rosmeri Kuhmmer Lazzaretti, Regina Kuhmmer Notti, Eduardo Sprinz & Vanessa Suñé Mattevi. (2020) Investigation of SIRT1 gene variants in HIV-associated lipodystrophy and metabolic syndrome. Genetics and Molecular Biology 43:1.
Crossref
Xiao lin Lin, Kai Li, Zhuo Yang, Baogui Chen & Tao Zhang. (2020) Dulcitol suppresses proliferation and migration of hepatocellular carcinoma via regulating SIRT1/p53 pathway. Phytomedicine 66, pages 153112.
Crossref
Yi Wang & Wing-Fu Lai. 2020. Systemic Delivery Technologies in Anti-Aging Medicine: Methods and Applications. Systemic Delivery Technologies in Anti-Aging Medicine: Methods and Applications 3 37 .
Shu IURA, Yuusei OJIMA, Yoshiaki AMAKURA, Morio YOSHIMURA, Atsushi SAWAMOTO, Satoshi OKUYAMA, Yoshiko FURUKAWA & Mitsunari NAKAJIMA. (2019) T-cell activation-inhibitory assay: a proposed novel method for screening caloric restriction mimetics. Biomedical Research 40:6, pages 235-241.
Crossref
Cuiping Wang, Xia Sun, Zhi Qiu & Anyong Chen. (2020) RETRACTED ARTICLE: MiR-138-5p exacerbates hypoxia/reperfusion-induced heart injury through the inactivation of SIRT1-PGC-1α. Inflammation Research 68:10, pages 867-876.
Crossref
Jia LiuXuan LiQingguo LuDi RenXiaodong SunThomas RousselleJi Li & Jiyan Leng. (2019) AMPK: a balancer of the renin–angiotensin system. Bioscience Reports 39:9.
Crossref
Esmaeil Yousefi Rad, Somayeh Saboori, Mahmoud Djalali, Ebrahim Falahi, Sanaz Gholamhosseini & Ebrahim Nematipour. (2019) Omega-3 fatty acids and vitamin E supplementation can affect gene expressions of SIRT1, FOXO1 and UCP-2 in coronary artery disease patients. Obesity Medicine 15, pages 100116.
Crossref
Surai, Kochish, Fisinin & Kidd. (2019) Antioxidant Defence Systems and Oxidative Stress in Poultry Biology: An Update. Antioxidants 8:7, pages 235.
Crossref
Itay Bentov, Stephen J. Kaplan, Tam N. Pham & May J. Reed. (2019) Frailty assessment: from clinical to radiological tools. British Journal of Anaesthesia 123:1, pages 37-50.
Crossref
Katya Vargas-Ortiz, Victoriano Pérez-Vázquez & Maciste H. Macías-Cervantes. (2019) Exercise and Sirtuins: A Way to Mitochondrial Health in Skeletal Muscle. International Journal of Molecular Sciences 20:11, pages 2717.
Crossref
Chongyuan Lin, Mengdi Liu, Xiaojing Zhu, Mengmeng Zhang, Shanliang Xu, Danli Wang & Yunlong Zhao. (2019) Cloning and expression of the lifespan-associated protein Sir2 from Daphnia pulex. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 231, pages 1-10.
Crossref
Dong Ryeol Ryu, Mi Ra Yu, Kyoung Hye Kong, Hyoungnae Kim, Soon Hyo Kwon, Jin Seok Jeon, Dong Cheol Han & Hyunjin Noh. (2019) Sirt1-hypoxia-inducible factor-1α interaction is a key mediator of tubulointerstitial damage in the aged kidney. Aging Cell 18:2, pages e12904.
Crossref
Qiangsheng Hu, Yi Qin, Shunrong Ji, Wenyan Xu, Wensheng Liu, Qiqing Sun, Zheng Zhang, Mengqi Liu, Quanxing Ni, Xianjun Yu & Xiaowu Xu. (2019) UHRF1 promotes aerobic glycolysis and proliferation via suppression of SIRT4 in pancreatic cancer. Cancer Letters.
Crossref
Swip Draijer, Inês Chaves & Marco F.M. Hoekman. (2019) The circadian clock in adult neural stem cell maintenance. Progress in Neurobiology 173, pages 41-53.
Crossref
Samantha S. Romanick, Kristen Morrill, Andrew Hostler, Levi W. Evans, Yiqiu Shen, Allison Matsumura, Haleigh Piotrowski, Lorrayny G. Silva, Antonio P. Faciola & Bradley S. Ferguson. (2018) HDAC1/2‐mediated regulation of JNK and ERK phosphorylation in bovine mammary epithelial cells in response to TNF‐α. Journal of Cellular Physiology 234:2, pages 1088-1098.
Crossref
Jixiang Zhang & Hui-Lin Pan. 2019. Epigenetics of Chronic Pain. Epigenetics of Chronic Pain 85 98 .
Lin-sheng Gui, Sayed Haidar Abbas Raza, Matthew Garcia, Yong-gang Sun, Irfan Ullah & Yin-cang Han. (2018) Genetic variants in the SIRT6 transcriptional regulatory region affect gene activity and carcass quality traits in indigenous Chinese beef cattle (Bos taurus). BMC Genomics 19:1.
Crossref
Rachel S Fletcher & Gareth G Lavery. (2018) The emergence of the nicotinamide riboside kinases in the regulation of NAD+ metabolism. Journal of Molecular Endocrinology 61:3, pages R107-R121.
Crossref
Raúl A. Salazar-González, Eneida Turiján-Espinoza, David W. Hein, Rosa C. Milán-Segovia, Edith E. Uresti-Rivera & Diana P. Portales-Pérez. (2018) Expression and genotype-dependent catalytic activity of N-acetyltransferase 2 (NAT2) in human peripheral blood mononuclear cells and its modulation by Sirtuin 1. Biochemical Pharmacology 156, pages 340-347.
Crossref
Ananth K Vellimana, Deepti Diwan, Julian Clarke, Jeffrey M Gidday & Gregory J Zipfel. (2018) SIRT1 Activation. Neurosurgery 65:CN_suppl_1, pages 1-5.
Crossref
B. Poljsak & I. Milisav. (2018) Vitamin B3 forms as precursors to NAD+: Are they safe?. Trends in Food Science & Technology 79, pages 198-203.
Crossref
Menizibeya O. Welcome & Nikos E. Mastorakis. (2018) Emerging Concepts in Brain Glucose Metabolic Functions: From Glucose Sensing to How the Sweet Taste of Glucose Regulates Its Own Metabolism in Astrocytes and Neurons. NeuroMolecular Medicine 20:3, pages 281-300.
Crossref
In-Bong Song, Hyejung Gu, Hye-Ju Han, Na-Young Lee, Ji-Yun Cha, Yeon-Kyong Son & Jungkee Kwon. (2018) Omega-7 inhibits inflammation and promotes collagen synthesis through SIRT1 activation. Applied Biological Chemistry 61:4, pages 433-439.
Crossref
Tiantian Qin, Weihua Liu, Junfeng Huo, Leilei Li, Xueyan Zhang, Xiaoli Shi, Jinlei Zhou & Cong Wang. (2018) SIRT1 expression regulates the transformation of resistant esophageal cancer cells via the epithelial-mesenchymal transition. Biomedicine & Pharmacotherapy 103, pages 308-316.
Crossref
H. Li, L. Hao, Y. Li & Rong Wang. (2018) Reducing CXCR4 Resulted in Impairing Proliferation and Promoting Aging. The journal of nutrition, health & aging 22:7, pages 785-789.
Crossref
Nana Liu, Jing Chen, Dongmei Gao, Wenhua Li & Di Zheng. (2018) Astaxanthin attenuates contrast agent-induced acute kidney injury in vitro and in vivo via the regulation of SIRT1/FOXO3a expression. International Urology and Nephrology 50:6, pages 1171-1180.
Crossref
Zahra Arab Sadeghabadi, Mitra Nourbakhsh, Parvin Pasalar, Solaleh Emamgholipour, Abolfazl Golestani, Bagher Larijani & Maryam Razzaghy-Azar. (2018) Reduced gene expression of sirtuins and active AMPK levels in children and adolescents with obesity and insulin resistance. Obesity Research & Clinical Practice 12:2, pages 167-173.
Crossref
Kana Tanabe, Jiaan Liu, Daiki Kato, Hitoshi Kurumizaka, Kenzo Yamatsugu, Motomu Kanai & Shigehiro A. Kawashima. (2018) LC–MS/MS-based quantitative study of the acyl group- and site-selectivity of human sirtuins to acylated nucleosomes. Scientific Reports 8:1.
Crossref
Liu Xu, Shuang Xu, Lifang Lin, Xi Gu, Congcong Fu, Yingying Fang, Xiaowen Li & Xuemin Wang. (2018) High-fat Diet Mediates Anxiolytic-like Behaviors in a Time-dependent Manner Through the Regulation of SIRT1 in the Brain. Neuroscience 372, pages 237-245.
Crossref
Nurul Fatihah Mohamad Nasir, Azalina Zainuddin & Shaharum Shamsuddin. (2017) Emerging Roles of Sirtuin 6 in Alzheimer’s Disease. Journal of Molecular Neuroscience 64:2, pages 157-161.
Crossref
Sabita N. Saldanha & Trygve O. Tollefsbol. 2018. Epigenetics in Human Disease. Epigenetics in Human Disease 219 247 .
Xiaoru Sun, Zhihong Chen & Xiangdong Wang. 2018. Genomic Approach to Asthma. Genomic Approach to Asthma 243 275 .
Yi-Rong Li, Shiming Li & Chi-Chien Lin. (2018) Effect of resveratrol and pterostilbene on aging and longevity. BioFactors 44:1, pages 69-82.
Crossref
Khaldoun Rifaï, Gaëlle Judes, Mouhamed Idrissou, Marine Daures, Yves-Jean Bignon, Frédérique Penault-Llorca & Dominique Bernard-Gallon. (2017) Dual SIRT1 expression patterns strongly suggests its bivalent role in human breast cancer. Oncotarget 8:67, pages 110922-110930.
Crossref
Laura C. D. Pomatto & Kelvin J. A. Davies. (2017) The role of declining adaptive homeostasis in ageing. The Journal of Physiology 595:24, pages 7275-7309.
Crossref
Hongyan Li & Rong Wang. (2017) Blocking SIRT1 inhibits cell proliferation and promotes aging through the PI3K/AKT pathway. Life Sciences 190, pages 84-90.
Crossref
Lina Xu, Longbin Jia, Qingyun Wang, Jing Hou, Shifang Li & Junfang Teng. (2017) Salidroside attenuates hypoxia/reoxygenation‑induced human brain vascular smooth muscle cell injury by activating the SIRT1/FOXO3α pathway. Experimental and Therapeutic Medicine.
Crossref
Liang Chang, Liang Xi, Yubin Liu, Rui Liu, Zhongshi Wu & Zhixiang Jian. (2017) SIRT5 promotes cell proliferation and invasion in hepatocellular carcinoma by targeting E2F1. Molecular Medicine Reports.
Crossref
Silvia Carloni, Giulia Riparini, Giuseppe Buonocore & Walter Balduini. (2017) Rapid modulation of the silent information regulator 1 by melatonin after hypoxia-ischemia in the neonatal rat brain. Journal of Pineal Research 63:3, pages e12434.
Crossref
Wei Yang, Xiaomin Kang, Na Qin, Feng Li, Xinxin Jin, Zhengmin Ma, Zhuang Qian & Shufang Wu. (2017) Melatonin protects chondrocytes from impairment induced by glucocorticoids via NAD + -dependent SIRT1. Steroids 126, pages 24-29.
Crossref
Young Hyun Jung, Hyun Jik Lee, Jun Sung Kim, Sei-Jung Lee & Ho Jae Han. (2017) EphB2 signaling-mediated Sirt3 expression reduces MSC senescence by maintaining mitochondrial ROS homeostasis. Free Radical Biology and Medicine 110, pages 368-380.
Crossref
Alireza Hasaninejad, Fatemeh Mandegani, Maryam Beyrati, Ammar Maryamabadi & Gholamhossein Mohebbi. (2017) Highly Efficient Synthesis of Spirooxindole, Spiroacenaphthylene and Bisbenzo[b]pyran Derivatives and Evaluation of Their Inhibitory Activity against Sirtuin 2. ChemistrySelect 2:23, pages 6784-6796.
Crossref
Thea van den Bosch, Marcel Kwiatkowski, Rainer Bischoff & Frank J Dekker. (2017) Targeting transcription factor lysine acetylation in inflammatory airway diseases. Epigenomics 9:7, pages 1013-1028.
Crossref
Yasir S. Elhassan, Andrew A. Philp & Gareth G. Lavery. (2017) Targeting NAD+ in Metabolic Disease: New Insights Into an Old Molecule. Journal of the Endocrine Society 1:7, pages 816-835.
Crossref
Morena MartucciRita OstanFiammetta BiondiElena BellavistaCristina FabbriClaudia BertarelliStefano SalvioliMiriam CapriClaudio FranceschiAurelia Santoro. (2017) Mediterranean diet and inflammaging within the hormesis paradigm. Nutrition Reviews 75:6, pages 442-455.
Crossref
Sanjay Guleria, Jingwen Zhou & Mattheos A.G. Koffas. 2017. Industrial Biotechnology. Industrial Biotechnology 309 336 .
Helin Feng, Jin Wang, Jianfa Xu, Congcong Xie, Fulu Gao & Zhiyong Li. (2017) The expression of SIRT1 regulates the metastaticplasticity of chondrosarcoma cells by inducing epithelial-mesenchymal transition. Scientific Reports 7:1.
Crossref
K. Kainz, J. Tadic, A. Zimmermann, T. Pendl, D. Carmona-Gutierrez, C. Ruckenstuhl, T. Eisenberg & F. Madeo. 2017. Molecular Characterization of Autophagic Responses, Part B. Molecular Characterization of Autophagic Responses, Part B 367 394 .
Sharmistha Dey. 2017. Topics in Biomedical Gerontology. Topics in Biomedical Gerontology 57 66 .
Punita Jain, Priyanka Sharma, Anju Shrivastava & Shweta Saran. 2017. Topics in Biomedical Gerontology. Topics in Biomedical Gerontology 35 55 .
Renu Yadav, Soram Idiyasan Chanu, Kritika Raj, Nisha & Surajit Sarkar. 2017. Topics in Biomedical Gerontology. Topics in Biomedical Gerontology 3 33 .
Hui Dong, Sihan Yang, Qiping Zhao, Hongyu Han, Shunhai Zhu, Xuelong Zhu, Cong Li, Ziwen Wang, Weili Xia, Qifei Men, Liangyu Yang & Bing Huang. (2016) Molecular characterization and protective efficacy of silent information regulator 2A from Eimeria tenella. Parasites & Vectors 9:1.
Crossref
Graziamaria Corbi, Valeria Conti, Sergio Davinelli, Giovanni Scapagnini, Amelia Filippelli & Nicola Ferrara. (2016) Dietary Phytochemicals in Neuroimmunoaging: A New Therapeutic Possibility for Humans?. Frontiers in Pharmacology 7.
Crossref
Wei YangXiaomin KangJiali LiuHuixia LiZhengmin MaXinxin JinZhuang QianTianping XieNa QinDongxu FengWenjie PanQian Chen, Hongzhi SunShufang Wu. (2016) Clock Gene Bmal1 Modulates Human Cartilage Gene Expression by Crosstalk With Sirt1. Endocrinology 157:8, pages 3096-3107.
Crossref
Samik Bindu, Vinodkumar B. Pillai & Mahesh P. Gupta. (2016) Role of Sirtuins in Regulating Pathophysiology of the Heart. Trends in Endocrinology & Metabolism 27:8, pages 563-573.
Crossref
Niek GJ Leus, Martijn RH Zwinderman & Frank J Dekker. (2016) Histone deacetylase 3 (HDAC 3) as emerging drug target in NF-κB-mediated inflammation. Current Opinion in Chemical Biology 33, pages 160-168.
Crossref
Hye Kim. (2016) Protective Effect of Garlic on Cellular Senescence in UVB-Exposed HaCaT Human Keratinocytes. Nutrients 8:8, pages 464.
Crossref
Oscar V. Torres, Bruce Ladenheim, Subramaniam Jayanthi, Michael T. McCoy, Irina N. Krasnova, Francois A. Vautier & Jean Lud Cadet. (2015) An Acute Methamphetamine Injection Downregulates the Expression of Several Histone Deacetylases (HDACs) in the Mouse Nucleus Accumbens: Potential Regulatory Role of HDAC2 Expression. Neurotoxicity Research 30:1, pages 32-40.
Crossref
Yulong Cai, Le Xu, Haiwei Xu & Xiaotang Fan. (2015) SIRT1 and Neural Cell Fate Determination. Molecular Neurobiology 53:5, pages 2815-2825.
Crossref
Yi-Chao Hsu, Yu-Ting Wu, Ting-Hsien Yu & Yau-Huei Wei. (2016) Mitochondria in mesenchymal stem cell biology and cell therapy: From cellular differentiation to mitochondrial transfer. Seminars in Cell & Developmental Biology 52, pages 119-131.
Crossref
Balamurugan Ramatchandirin, Mohanraj Sadasivam, Arun Kannan & Chidambaram Prahalathan. (2015) Sirtuin 4 Regulates Lipopolysaccharide Mediated Leydig Cell Dysfunction. Journal of Cellular Biochemistry 117:4, pages 904-916.
Crossref
Sherine M. Rizk, Nancy N. Shahin & Olfat G. Shaker. (2016) Association between SIRT1 Gene Polymorphisms and Breast Cancer in Egyptians. PLOS ONE 11:3, pages e0151901.
Crossref
P.F. Surai & V.I. Fisinin. 2016. Handbook of cholesterol. Handbook of cholesterol 451 482 .
Irene Maeve Rea, Margaret Dellet & Ken I. Mills. (2015) Living long and ageing well: is epigenomics the missing link between nature and nurture?. Biogerontology 17:1, pages 33-54.
Crossref
Luca Perico, Marina Morigi & Ariela Benigni. (2016) Mitochondrial Sirtuin 3 and Renal Diseases. Nephron 134:1, pages 14-19.
Crossref
Gi-Su Oh, Hyung-Jin Kim, AiHua Shen, Su-Bin Lee, Sei-Hoon Yang, Hyeok Shim, Eun-Young Cho, Kang-Beom Kwon, Tae Hwan Kwak & Hong-Seob So. (2016) New Therapeutic Concept of NAD Redox Balance for Cisplatin Nephrotoxicity. BioMed Research International 2016, pages 1-12.
Crossref
Raffaele Palmirotta, Mauro Cives, David Della-Morte, Barbara Capuani, Davide Lauro, Fiorella Guadagni & Franco Silvestris. (2016) Sirtuins and Cancer: Role in the Epithelial-Mesenchymal Transition. Oxidative Medicine and Cellular Longevity 2016, pages 1-9.
Crossref
Mingyu Lee, Dae Woo Kim, Haejin Yoon, Daeho So, Roza Khalmuratova, Chae-Seo Rhee, Jong-Wan Park & Hyun-Woo Shin. (2016) Sirtuin 1 attenuates nasal polypogenesis by suppressing epithelial-to-mesenchymal transition. Journal of Allergy and Clinical Immunology 137:1, pages 87-98.e7.
Crossref
Thea van den Bosch, Niek G.J. Leus, Tirza Timmerman & Frank J. Dekker. 2016. Drug Discovery in Cancer Epigenetics. Drug Discovery in Cancer Epigenetics 191 208 .
Jimin Lin, Yanchao Pan & Jiangyun Wang. (2016) NAD + and its precursors in human longevity . Quantitative Biology 3:4, pages 193-198.
Crossref
Junfeng Han, Meilin Wei, Qianqian Wang, Xu Li, Chaoyu Zhu, Yueqin Mao, Li Wei, Yongning Sun & Weiping Jia. (2015) Association of Genetic Variants of SIRT1 With Type 2 Diabetes Mellitus . Gene Expression 16:4, pages 177-185.
Crossref
Chuanhui Dong, David Della-Morte, Digna Cabral, Liyong Wang, Susan H. Blanton, Chaturvedi Seemant, Ralph L. Sacco & Tatjana Rundek. (2015) Sirtuin/Uncoupling Protein Gene Variants and Carotid Plaque Area and Morphology. International Journal of Stroke 10:8, pages 1247-1252.
Crossref
Wei Hong, Xiao-ya Xu, Zhao-hui Qiu, Jian-jun Gao, Zhan-ying Wei, Li Zhen, Xiao-li Zhang & Zhi-bing Ye. (2015) Sirt1 is involved in decreased bone formation in aged apolipoprotein E-deficient mice. Acta Pharmacologica Sinica 36:12, pages 1487-1496.
Crossref
Anthony J. Donato, R. Garrett Morgan, Ashley E. Walker & Lisa A. Lesniewski. (2015) Cellular and molecular biology of aging endothelial cells. Journal of Molecular and Cellular Cardiology 89, pages 122-135.
Crossref
Neil Copes, Clare Edwards, Dale Chaput, Mariam Saifee, Iosif Barjuca, Daniel Nelson, Alyssa Paraggio, Patrick Saad, David Lipps, Stanley M. StevensJrJr & Patrick C. Bradshaw. (2015) Metabolome and proteome changes with aging in Caenorhabditis elegans. Experimental Gerontology 72, pages 67-84.
Crossref
Dutt Way Wong, Tomoko Soga & Ishwar S. Parhar. (2015) Aging and chronic administration of serotonin-selective reuptake inhibitor citalopram upregulate Sirt4 gene expression in the preoptic area of male mice. Frontiers in Genetics 6.
Crossref
Ellen K. Quarles, Dao-Fu Dai, Autumn Tocchi, Nathan Basisty, Lemuel Gitari & Peter S. Rabinovitch. (2015) Quality control systems in cardiac aging. Ageing Research Reviews 23, pages 101-115.
Crossref
Hyung-Jin Kim, Gi-Su Oh, AiHua Shen, Su-Bin Lee, Dipendra Khadka, Arpana Pandit, Hyeok Shim, Sei-Hoon Yang, Eun-Young Cho, Jeho Song, Tae Hwan Kwak, Seong-Kyu Choe, Raekil Park & Hong-Seob So. (2015) Nicotinamide adenine dinucleotide: An essential factor in preserving hearing in cisplatin-induced ototoxicity. Hearing Research 326, pages 30-39.
Crossref
Luca Perico, Giuseppe Remuzzi & Ariela Benigni. (2015) Sirtuin 3 in acute kidney injury. Oncotarget 6:19, pages 16814-16815.
Crossref
Ferdinando ChiaradonnaIros BarozziClaudia MiccoloGabriele BucciRoberta PaloriniLorenzo FornasariOronza A. BotrugnoGiancarlo PruneriMichele MasulloAlfonso PassafaroViviana E. GalimbertiValeria R. FantinVictoria M. RichonSalvatore PeceGiuseppe VialePier Paolo Di FioreGiulio DraettaPier Giuseppe PelicciSaverio MinucciSusanna Chiocca. (2015) Redox-Mediated Suberoylanilide Hydroxamic Acid Sensitivity in Breast Cancer. Antioxidants & Redox Signaling 23:1, pages 15-29.
Crossref
Rosaria BenedettiMariarosaria ConteLucia Altucci. (2015) Targeting Histone Deacetylases in Diseases: Where Are We?. Antioxidants & Redox Signaling 23:1, pages 99-126.
Crossref
Jun Hyun Jeong, Hee Geun Park, Young Ran Lee & Wang Lok Lee. (2015) Moderate exercise training is more effective than resveratrol supplementation for ameliorating lipid metabolic complication in skeletal muscle of high fat diet-induced obese mice. Journal of Exercise Nutrition and Biochemistry 19:2, pages 131-137.
Crossref
Wonchung Lim, Myeong Kuk Shim, Sikwan Kim & YoungJoo Lee. (2015) Red ginseng represses hypoxia-induced cyclooxygenase-2 through sirtuin1 activation. Phytomedicine 22:6, pages 597-604.
Crossref
Nady Braidy, Anne Poljak, Ross Grant, Tharusha Jayasena, Hussein Mansour, Tailoi Chan-Ling, George Smythe, Perminder Sachdev & Gilles J. Guillemin. (2015) Differential expression of sirtuins in the aging rat brain. Frontiers in Cellular Neuroscience 9.
Crossref
Belém Sampaio-Marques & Paula Ludovico. (2015) Sirtuins and Proteolytic Systems: Implications for Pathogenesis of Synucleinopathies. Biomolecules 5:2, pages 735-757.
Crossref
Xinlei Xia, Ji Guo, Feizhou Lu & Jianyuan Jiang. (2015) SIRT1 Plays a Protective Role in Intervertebral Disc Degeneration in a Puncture-induced Rodent Model. Spine 40:9, pages E515-E524.
Crossref
Nassim Dali-Youcef, Sébastien Froelich, François-Marie Moussallieh, Salvatore Chibbaro, Georges Noël, Izzie J. Namer, Sami Heikkinen & Johan Auwerx. (2015) Gene Expression Mapping of Histone Deacetylases and Co-factors and Correlation with Survival Time and 1H-HRMAS Metabolomic Profile in Human Gliomas. Scientific Reports 5:1.
Crossref
Gillian Margaret Tannahill, Nunzio Iraci, Edoardo Gaude, Christian Frezza & Stefano Pluchino. (2015) Metabolic Reprograming of Mononuclear Phagocytes in Progressive Multiple Sclerosis. Frontiers in Immunology 6.
Crossref
David Della-Morte, Chuanhui Dong, Ashley Beecham, Liyong Wang, Digna Cabral, Matthew S. Markert, Susan H. Blanton, Ralph L. Sacco & Tatjana Rundek. (2015) Relationship between sirtuin and mitochondrial uncoupling protein genes and carotid artery stiffness. Translational Research 165:2, pages 358-359.
Crossref
Li Li Ji & Chounghun Kang. (2015) Role of PGC-1α in Sarcopenia: Etiology and Potential Intervention - A Mini-Review. Gerontology 61:2, pages 139-148.
Crossref
Taki Sakai, Yotaro Matsumoto, Minoru Ishikawa, Kazuyuki Sugita, Yuichi Hashimoto, Nobuhiko Wakai, Akio Kitao, Era Morishita, Chikashi Toyoshima, Tomoatsu Hayashi & Tetsu Akiyama. (2015) Design, synthesis and structure–activity relationship studies of novel sirtuin 2 (SIRT2) inhibitors with a benzamide skeleton. Bioorganic & Medicinal Chemistry 23:2, pages 328-339.
Crossref
Sabita N. Saldanha & Louis Patrick Watanabe. 2015. Epigenetics and Dermatology. Epigenetics and Dermatology 379 406 .
Li Li Ji. 2015. Nutrition, Exercise and Epigenetics: Ageing Interventions. Nutrition, Exercise and Epigenetics: Ageing Interventions 101 125 .
Chong Hao, Peng-Xi Zhu, Xue Yang, Zhi-Peng Han, Jing-Hua Jiang, Chen Zong, Xu-Guang Zhang, Wen-Ting Liu, Qiu-Dong Zhao, Ting-Ting Fan, Li Zhang & Li-Xin Wei. (2014) Overexpression of SIRT1 promotes metastasis through epithelial-mesenchymal transition in hepatocellular carcinoma. BMC Cancer 14:1.
Crossref
InYoung Kim & Yu-Ying He. (2014) Ultraviolet radiation-induced non-melanoma skin cancer: Regulation of DNA damage repair and inflammation. Genes & Diseases 1:2, pages 188-198.
Crossref
Monica Colitti & Stefano Grasso. (2014) Nutraceuticals and regulation of adipocyte life: Premises or promises. BioFactors 40:4, pages 398-418.
Crossref
Douglas R. Seals, Rachelle E. Kaplon, Rachel A. Gioscia-Ryan & Thomas J. LaRocca. (2014) You're Only as Old as Your Arteries: Translational Strategies for Preserving Vascular Endothelial Function with Aging. Physiology 29:4, pages 250-264.
Crossref
George A. Porter, William R. Urciuoli, Paul S. Brookes & Sergiy M. Nadtochiy. (2014) SIRT3 deficiency exacerbates ischemia-reperfusion injury: implication for aged hearts. American Journal of Physiology-Heart and Circulatory Physiology 306:12, pages H1602-H1609.
Crossref
VINCENT GRANDPERRET, VALÉRIE NICOLAS-FRANCÈS, DAVID WENDEHENNE & STÉPHANE BOURQUE. (2014) Type-II histone deacetylases: elusive plant nuclear signal transducers. Plant, Cell & Environment 37:6, pages 1259-1269.
Crossref
Marianne R. Smith, Adeela Syed, Tamas Lukacsovich, Judy Purcell, Brett A. Barbaro, Shane A. Worthge, Stephen R. Wei, Giuseppe Pollio, Letizia Magnoni, Carla Scali, Luisa Massai, Davide Franceschini, Michela Camarri, Marco Gianfriddo, Enrica Diodato, Russell Thomas, Ozgun Gokce, S.J. Tabrizi, Andrea Caricasole, Bernard Landwehrmeyer, Liliana Menalled, Carol Murphy, Sylvie Ramboz, Ruth Luthi-Carter, Goran Westerberg & J. Lawrence Marsh. (2014) A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease. Human Molecular Genetics 23:11, pages 2995-3007.
Crossref
Leopold Rehan, Krystyna Laszki-Szcząchor, Małgorzata Sobieszczańska & Dorota Polak-Jonkisz. (2014) SIRT1 and NAD as regulators of ageing. Life Sciences 105:1-2, pages 1-6.
Crossref
Shigeru Katayama, Rie Imai, Haruka Sugiyama & Soichiro Nakamura. (2014) Oral Administration of Soy Peptides Suppresses Cognitive Decline by Induction of Neurotrophic Factors in SAMP8 Mice. Journal of Agricultural and Food Chemistry 62:16, pages 3563-3569.
Crossref
Alba Rebollo, Núria Roglans, Miguel Baena, Rosa M. Sánchez, Manel Merlos, Marta Alegret & Juan C. Laguna. (2014) Liquid fructose downregulates Sirt1 expression and activity and impairs the oxidation of fatty acids in rat and human liver cells. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1841:4, pages 514-524.
Crossref
Lionel Sacconnay, Melissa Angleviel, Giuseppe Marco Randazzo, Marcos Marçal Ferreira Queiroz, Emerson Ferreira Queiroz, Jean-Luc Wolfender, Pierre-Alain Carrupt & Alessandra Nurisso. (2014) Computational Studies on Sirtuins from Trypanosoma cruzi: Structures, Conformations and Interactions with Phytochemicals. PLoS Neglected Tropical Diseases 8:2, pages e2689.
Crossref
Lingling Zeng, Yang Yang, Yujuan Hu, Yu Sun, Zhengde Du, Zhen Xie, Tao Zhou & Weijia Kong. (2014) Age-Related Decrease in the Mitochondrial Sirtuin Deacetylase Sirt3 Expression Associated with ROS Accumulation in the Auditory Cortex of the Mimetic Aging Rat Model. PLoS ONE 9:2, pages e88019.
Crossref
Insung ParkYool LeeHee-Dae KimKyungjin Kim. (2014) Effect of Resveratrol, a SIRT1 Activator, on the Interactions of the CLOCK/BMAL1 Complex. Endocrinology and Metabolism 29:3, pages 379.
Crossref
Haejin Yoon, Seung-Hyun Shin, Dong Hoon Shin, Yang-Sook Chun & Jong-Wan Park. (2014) Differential roles of Sirt1 in HIF-1α and HIF-2α mediated hypoxic responses. Biochemical and Biophysical Research Communications 444:1, pages 36-43.
Crossref
Mitchell H. Rosner, Dinna N. Cruz & Claudio Ronco. 2014. Managing Renal Injury in the Elderly Patient. Managing Renal Injury in the Elderly Patient 33 46 .
Patricia K. Farris. 2013. Cosmeceuticals and Cosmetic Practice. Cosmeceuticals and Cosmetic Practice 165 172 .
Carolin Cornelius, Angela Trovato Salinaro, Maria Scuto, Vincenzo Fronte, Maria Teresa Cambria, Manuela Pennisi, Rita Bella, Pietro Milone, Antonio Graziano, Rosalia Crupi, Salvatore Cuzzocrea, Giovanni Pennisi & Vittorio Calabrese. (2013) Cellular stress response, sirtuins and UCP proteins in Alzheimer disease: role of vitagenes. Immunity & Ageing 10:1.
Crossref
David Della-MorteCamillo Ricordi & Tatjana Rundek. (2013) The fountain of youth: role of sirtuins in aging and regenerative medicine. Regenerative Medicine 8:6, pages 681-683.
Crossref
Chounghun Kang, Eunhee Chung, Gary Diffee & Li Li Ji. (2013) Exercise training attenuates aging-associated mitochondrial dysfunction in rat skeletal muscle: Role of PGC-1α. Experimental Gerontology 48:11, pages 1343-1350.
Crossref
Josef Brandauer, Sara G. Vienberg, Marianne A. Andersen, Stine Ringholm, Steve Risis, Per S. Larsen, Jonas M. Kristensen, Christian Frøsig, Lotte Leick, Joachim Fentz, Sebastian Jørgensen, Bente Kiens, Jørgen F. P. Wojtaszewski, Erik A. Richter, Juleen R. Zierath, Laurie J. Goodyear, Henriette Pilegaard & Jonas T. Treebak. (2013) AMP‐activated protein kinase regulates nicotinamide phosphoribosyl transferase expression in skeletal muscle. The Journal of Physiology 591:20, pages 5207-5220.
Crossref
Anthony J. Donato, Ashley E. Walker, Katherine A. Magerko, R. Colton Bramwell, Alex D. Black, Grant D. Henson, Brooke R. Lawson, Lisa A. Lesniewski & Douglas R. Seals. (2013) Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice. Aging Cell 12:5, pages 772-783.
Crossref
Jun Mori, Liyan Zhang, Gavin Y. Oudit & Gary D. Lopaschuk. (2013) Impact of the renin–angiotensin system on cardiac energy metabolism in heart failure. Journal of Molecular and Cellular Cardiology 63, pages 98-106.
Crossref
Silvia Jesús, Pilar Gómez-Garre, Fátima Carrillo, María T. Cáceres-Redondo, Ismael Huertas-Fernández, Inmaculada Bernal-Bernal, Marta Bonilla-Toribio, Laura Vargas-González, Manuel Carballo & Pablo Mir. (2013) Genetic association of sirtuin genes and Parkinson’s disease. Journal of Neurology 260:9, pages 2237-2241.
Crossref
Alejandro Martin-MontalvoRafael de Cabo. (2013) Mitochondrial Metabolic Reprogramming Induced by Calorie Restriction. Antioxidants & Redox Signaling 19:3, pages 310-320.
Crossref
Alessandra Berry & Francesca Cirulli. (2013) The p66Shc gene paves the way for healthspan: Evolutionary and mechanistic perspectives. Neuroscience & Biobehavioral Reviews 37:5, pages 790-802.
Crossref
Brendan C. Dickson, Nicole D. Riddle, John S. Brooks, Theresa L. Pasha & Paul J. Zhang. (2013) Sirtuin 1 (SIRT1): a potential immunohistochemical marker and therapeutic target in soft tissue neoplasms with myoid differentiation. Human Pathology 44:6, pages 1125-1130.
Crossref
N. Dali-Youcef. (2013) « SIRTuinement vôtre » : fonctions métaboliques et perspectives thérapeutiques des sirtuines. Médecine des Maladies Métaboliques 7:3, pages 237-246.
Crossref
M.M. Essa, N. Braidy, M.I. Waly, Y.M. Al-Farsi, M. Al-Sharbati, S. Subash, A. Amanat, M.A. Al-Shaffaee & G.J. Guillemin. (2013) Impaired antioxidant status and reduced energy metabolism in autistic children. Research in Autism Spectrum Disorders 7:5, pages 557-565.
Crossref
Stephanie F. MacCallum, Michael J. Groves, John James, Karen Murray, Virginia Appleyard, Alan R. Prescott, Abed A. Drbal, Anna Nicolaou, Joan Cunningham, Sally Haydock, Ian G. Ganley, Nicholas J. Westwood, Philip J. Coates, Sonia Lain & Sudhir Tauro. (2013) Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6. Scientific Reports 3:1.
Crossref
Andrea Bednářová, Dalibor Kodrík & Natraj Krishnan. (2013) Nature’s Timepiece—Molecular Coordination of Metabolism and Its Impact on Aging. International Journal of Molecular Sciences 14:2, pages 3026-3049.
Crossref
Sonja Körner, Sebastian Böselt, Nadine Thau, Klaus Jan Rath, Reinhard Dengler & Susanne Petri. (2013) Differential Sirtuin Expression Patterns in Amyotrophic Lateral Sclerosis (ALS) Postmortem Tissue: Neuroprotective or Neurotoxic Properties of Sirtuins in ALS?. Neurodegenerative Diseases 11:3, pages 141-152.
Crossref
Weihai Ying. (2013) Roles of NAD + , PARP-1, and Sirtuins in Cell Death, Ischemic Brain Injury, and Synchrotron Radiation X-Ray-Induced Tissue Injury . Scientifica 2013, pages 1-11.
Crossref
Y. Ghinis-Hozumi, A. Antaramian, F. Villarroya, E. Piña & O. Mora. (2013) Potential role of sirtuins in livestock production. Animal 7:1, pages 101-108.
Crossref
Naoya Hayakawa, Motoko Shiozaki, Masahiro Shibata, Masato Koike, Yasuo Uchiyama, Nariaki Matsuura & Takahiro Gotow. (2013) Resveratrol affects undifferentiated and differentiated PC12 cells differently, particularly with respect to possible differences in mitochondrial and autophagic functions. European Journal of Cell Biology 92:1, pages 30-43.
Crossref
Wing-Fu Lai. (2013) Nucleic acid delivery: Roles in biogerontological interventions. Ageing Research Reviews 12:1, pages 310-315.
Crossref
Kristofer S. Fritz. 2013. Sirtuins. Sirtuins 191 201 .
Mu-Jun Chang, Jun-Hua Xiao, Yong Wang, Yong-Li Yan, Jun Yang & Jia-Ling Wang. (2012) 2, 3, 5, 4′-Tetrahydroxystilbene-2-O-Beta-D-Glucoside Improves Gastrointestinal Motility Disorders in STZ-Induced Diabetic Mice. PLoS ONE 7:12, pages e50291.
Crossref
Hayley R. Inglis, Judith M. Greer & Pamela A. McCombe. (2012) Gene Expression in the Spinal Cord in Female Lewis Rats with Experimental Autoimmune Encephalomyelitis Induced with Myelin Basic Protein. PLoS ONE 7:11, pages e48555.
Crossref

Displaying 200 of 321 citing articles. Use the download link below to view the full list of citing articles.

Download full citations list

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.