Citations (47)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (11)
Simone Giovannuzzi, Chad S. Hewitt, Alessio Nocentini, Clemente Capasso, Gabriele Costantino, Daniel P. Flaherty & Claudiu T. Supuran. (2022) Inhibition studies of bacterial α-carbonic anhydrases with phenols. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 666-671.
Read now
Read now
Run-Hui Zhang, Hong-Yan Guo, Hao Deng, Jinzi Li & Zhe-Shan Quan. (2021) Piperazine skeleton in the structural modification of natural products: a review. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 1165-1197.
Read now
Read now
Alejandro I. Lorenzo-Pouso, Mercedes Gallas-Torreira, Mario Pérez-Sayáns, Cintia M. Chamorro-Petronacci, Oscar Alvarez-Calderon, Bahi Takkouche, Claudiu T. Supuran & Abel García-García. (2020) Prognostic value of CAIX expression in oral squamous cell carcinoma: a systematic review and meta-analysis. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1258-1266.
Read now
Read now
Anu Rani, Amit Anand, Kewal Kumar & Vipan Kumar. (2019) Recent developments in biological aspects of chalcones: the odyssey continues. Expert Opinion on Drug Discovery 14:3, pages 249-288.
Read now
Read now
Sinan Bilginer, Halise Inci Gul, Feyza Sena Erdal, Hiroshi Sakagami, Serkan Levent, Ilhami Gulcin & Claudiu T. Supuran. (2019) Synthesis, cytotoxicities, and carbonic anhydrase inhibition potential of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolones. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1722-1729.
Read now
Read now
Bernhard Biersack, Khursheed Ahmed, Subhash Padhye & Rainer Schobert. (2018) Recent developments concerning the application of the Mannich reaction for drug design. Expert Opinion on Drug Discovery 13:1, pages 39-49.
Read now
Read now
Morteza Abdoli, Andrea Angeli, Murat Bozdag, Fabrizio Carta, Ali Kakanejadifard, Hamid Saeidian & Claudiu T. Supuran. (2017) Synthesis and carbonic anhydrase I, II, VII, and IX inhibition studies with a series of benzo[d]thiazole-5- and 6-sulfonamides. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 1071-1078.
Read now
Read now
Murat Bozdag, Silvia Bua, Sameh M. Osman, Zeid AlOthman & Claudiu T. Supuran. (2017) Carbonic anhydrase I, II, IV and IX inhibition with a series of 7-amino-3,4-dihydroquinolin-2(1H)-one derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 885-892.
Read now
Read now
Zhengxing Zhang, Joseph Lau, Chengcheng Zhang, Nadine Colpo, Alessio Nocentini, Claudiu T. Supuran, François Bénard & Kuo-Shyan Lin. (2017) Design, synthesis and evaluation of 18F-labeled cationic carbonic anhydrase IX inhibitors for PET imaging. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 722-730.
Read now
Read now
Marco Bragagni, Fabrizio Carta, Sameh M. Osman, Zeid AlOthman & Claudiu T. Supuran. (2017) Synthesis of an acridine orange sulfonamide derivative with potent carbonic anhydrase IX inhibitory action. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 701-706.
Read now
Read now
Halise Inci Gul, Cem Yamali, Fatma Yesilyurt, Hiroshi Sakagami, Kaan Kucukoglu, Ilhami Gulcin, Mustafa Gul & Claudiu T. Supuran. (2017) Microwave-assisted synthesis and bioevaluation of new sulfonamides. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 369-374.
Read now
Read now
Articles from other publishers (36)
Van‐Son Nguyen, Vo Thanh Cong & Tran Nguyen Minh An. (2023) A Review of the Synthesis and Biological Activity of Flavonoid Mannich Base Derivatives. ChemistrySelect 8:46.
Crossref
Crossref
Cem Yamali, Sedat Sevin, Merve Nenni, Mehtap Tugrak Sakarya, Recep Uyar, Abdurrahman Aygul, Mahmut Ulger, Recep Ilhan, Serkan Levent & Halise Inci Gul. (2023) Design, synthesis, and assessment of pharmacological properties of indole-based fluorinated chalcones and their benzenesulfonamide analogs. Chemical Papers 77:12, pages 7903-7918.
Crossref
Crossref
Alessandro Bonardi, Claudiu T. Supuran & Alessio Nocentini. 2022. Flavonoids and Phenolics. Flavonoids and Phenolics
330
383
.
Said Moshawih, Parham Hadikhani, Ayesha Fatima, Hui Poh Goh, Nurolaini Kifli, Vijay Kotra, Khang Wen Goh & Long Chiau Ming. (2022) Comparative analysis of an anthraquinone and chalcone derivatives-based virtual combinatorial library. A cheminformatics “proof-of-concept” study. Journal of Molecular Graphics and Modelling 117, pages 108307.
Crossref
Crossref
Gheorghe Roman. (2022) Anticancer Activity of Mannich Bases: A Review of Recent Literature. ChemMedChem 17:16.
Crossref
Crossref
Neha V. Bhilare, Vinayak S. Marulkar, Pramodkumar J. Shirote, Shailaja A. Dombe, Vilas J. Pise, Pallavi L. Salve, Shantakumar M. Biradar, Vishal D. Yadav, Prakash D. Jadhav, Anjali A. Bodhe, Smita P. Borkar, Prachi M. Ghadge, Pournima A. Shelar, Apurva V. Jadhav & Kirti C. Godse. (2022) Mannich Bases: Centrality in Cytotoxic Drug Design. Medicinal Chemistry 18:7, pages 735-756.
Crossref
Crossref
Shaik Ammaji, Shaik Masthanamma, Richie R. Bhandare, Sivakumar Annadurai & Afzal Basha Shaik. (2022) Antitubercular and antioxidant activities of hydroxy and chloro substituted chalcone analogues: Synthesis, biological and computational studies. Arabian Journal of Chemistry 15:2, pages 103581.
Crossref
Crossref
Cem Yamali, Halise Inci Gul, Gulsen Ozli, Andrea Angeli, Petek Ballar Kirmizibayrak, Burcu Erbaykent Tepedelen, Hiroshi Sakagami, Silvia Bua & Claudiu T. Supuran. (2021) Exploring of tumor-associated carbonic anhydrase isoenzyme IX and XII inhibitory effects and cytotoxicities of the novel N-aryl-1-(4-sulfamoylphenyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxamides. Bioorganic Chemistry 115, pages 105194.
Crossref
Crossref
Yang Ouyang, Juanjuan Li, Xinyue Chen, Xiaoyu Fu, Si Sun & Qi Wu. (2021) Chalcone Derivatives: Role in Anticancer Therapy. Biomolecules 11:6, pages 894.
Crossref
Crossref
Cem Yamali, Hiroshi Sakagami, Yoshihiro Uesawa, Kota Kurosaki, Keitaro Satoh, Yoshiko Masuda, Satoshi Yokose, Abdulilah Ece, Silvia Bua, Andrea Angeli, Claudiu T. Supuran & Halise Inci Gul. (2021) Comprehensive study on potent and selective carbonic anhydrase inhibitors: Synthesis, bioactivities and molecular modelling studies of 4-(3-(2-arylidenehydrazine-1-carbonyl)-5-(thiophen-2-yl)-1H-pyrazole-1-yl) benzenesulfonamides. European Journal of Medicinal Chemistry 217, pages 113351.
Crossref
Crossref
Cem YAMALI & Halise İnci GÜL. (2021) Cytotoxic effects of Mannich bases via induction of caspase-3 pathway on human oral squamous cell carcinoma. Journal of the Turkish Chemical Society Section A: Chemistry 8:1, pages 187-194.
Crossref
Crossref
Cem Yamali, Feyza Sena Engin, Sinan Bilginer, Mehtap Tugrak, Dilan Ozmen Ozgun, Gulsen Ozli, Serkan Levent, Begum Nurpelin Saglik, Yusuf Ozkay & Halise Inci Gul. (2020) Phenothiazine‐based chalcones as potential dual‐target inhibitors toward cholinesterases (AChE, BuChE) and monoamine oxidases (MAO‐A, MAO‐B). Journal of Heterocyclic Chemistry 58:1, pages 161-171.
Crossref
Crossref
Mehtap TUĞRAK, Cem YAMALI, Halise İnci GÜL & Yeliz DEMİR. (2020) Inhibitory effects of the chalcones towards carbonic anhydrase I, II and acetylcholinesterase enzymesŞalkonların karbonik anhidraz I, II ve asetilkolinesteraz enzimlerine karşı inhibisyon etkileri. Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi 13:3, pages 1138-1146.
Crossref
Crossref
K. Kucukoglu, H. I. Gul & H. Sakagami. (2020) Evaluation of Cytotoxic Properties of N,N'-bis[(1-aryl-3-heteroaryl)propylidene]-hydrazine dihydrochlorides. Pharmaceutical Chemistry Journal 54:8, pages 784-787.
Crossref
Crossref
Cem Yamali, Halise Inci Gul, Tahir Cakir, Yeliz Demir & Ilhami Gulcin. (2020) Aminoalkylated Phenolic Chalcones: Investigation of Biological Effects on Acetylcholinesterase and Carbonic Anhydrase I and II as Potential Lead Enzyme Inhibitors. Letters in Drug Design & Discovery 17:10, pages 1283-1292.
Crossref
Crossref
Mehtap TUĞRAK, Halise İnci GÜL, Barış ANIL & Hülya AKINCIOĞLU. (2020) Piperonal Artığı Taşıyan Şalkonların Dizaynı, Sentezi ve Biyolojik AktiviteleriDesign, Synthesis and Biological Activities of Chalcones with Piperonal Moiety. Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi 13:2, pages 620-630.
Crossref
Crossref
Sinan Bilginer, Halise I. Gul, Feyza S. Erdal, Hiroshi Sakagami & Ilhami Gulcin. (2020)
New halogenated chalcones with cytotoxic and carbonic anhydrase inhibitory properties: 6‐(3‐Halogenated phenyl‐2‐propen‐1‐oyl)‐2(3
H
)‐benzoxazolones
. Archiv der Pharmazie 353:6, pages 1900384.
Crossref
Crossref
Sinan BİLGİNER. (2020) Benzoksazolon Türevi Şalkon Bileşiklerinin Sentezi ve Biyoaktivitelerinin AraştırılmasıSynthesis and Bioactivities of Benzoxazolone Derivative Chalcone Compounds. Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi 13:1, pages 334-347.
Crossref
Crossref
Vishnu A. Adole, Ravindra H. Waghchaure, Thansing B. Pawar, Bapu S. Jagdale & Kailas H. Kapadnis. (2020) Synthesis, Molecular Structure, HOMO-LUMO and Spectroscopic Investigation of
(E)-1-(2,4-Dichloro-5-fluorophenyl)-3-(2,6-dichlorophenyl)prop-2-en-1-one:
A DFT Based Computational Exploration. Asian Journal of Organic & Medicinal Chemistry 5:3, pages 242-248.
Crossref
Crossref
Azize Gizem Uslu, Tuğçe Gür Maz, Alessio Nocentini, Erden Banoglu, Claudiu T. Supuran & Burcu Çalışkan. (2020) Benzimidazole derivatives as potent and isoform selective tumor-associated carbonic anhydrase IX/XII inhibitors. Bioorganic Chemistry 95, pages 103544.
Crossref
Crossref
Cem Yamali, Halise Inci Gul, Abdulilah Ece, Silvia Bua, Andrea Angeli, Hiroshi Sakagami, Ertan Sahin & Claudiu T. Supuran. (2019) Synthesis, biological evaluation and in silico modelling studies of 1,3,5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors. Bioorganic Chemistry 92, pages 103222.
Crossref
Crossref
Mehtap Tugrak, Halise Inci Gul, Kenjiro Bandow, Hiroshi Sakagami, Ilhami Gulcin, Yusuf Ozkay & Claudiu T. Supuran. (2019) Synthesis and biological evaluation of some new mono Mannich bases with piperazines as possible anticancer agents and carbonic anhydrase inhibitors. Bioorganic Chemistry 90, pages 103095.
Crossref
Crossref
Halise Inci Gul, Mehtap Tugrak, Mustafa Gul, Sertac Mazlumoglu, Hiroshi Sakagami, Ilhami Gulcin & Claudiu T. Supuran. (2019) New phenolic Mannich bases with piperazines and their bioactivities. Bioorganic Chemistry 90, pages 103057.
Crossref
Crossref
Alejandro I. Lorenzo-Pouso, Mario Pérez-Sayáns, Samuel Rodríguez-Zorrilla, Cintia Chamorro-Petronacci & Abel García-García. (2019) Dissecting the Proton Transport Pathway in Oral Squamous Cell Carcinoma: State of the Art and Theranostics Implications. International Journal of Molecular Sciences 20:17, pages 4222.
Crossref
Crossref
Kaan Kucukoglu, Halise Inci Gul, Parham Taslimi, Ilhami Gulcin & Claudiu T. Supuran. (2019) Investigation of inhibitory properties of some hydrazone compounds on hCA I, hCA II and AChE enzymes. Bioorganic Chemistry 86, pages 316-321.
Crossref
Crossref
Dilan Ozmen Ozgun, Halise Inci Gul, Cem Yamali, Hiroshi Sakagami, Ilhami Gulcin, Murat Sukuroglu & Claudiu T. Supuran. (2019) Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity. Bioorganic Chemistry 84, pages 511-517.
Crossref
Crossref
Mehtap Tugrak, Halise Inci Gul, Hiroshi Sakagami, Ilhami Gulcin & Claudiu T. Supuran. (2018) New azafluorenones with cytotoxic and carbonic anhydrase inhibitory properties: 2-Aryl-4-(4-hydroxyphenyl)-5H-indeno[1,2-b]pyridin-5-ones. Bioorganic Chemistry 81, pages 433-439.
Crossref
Crossref
Halise Inci Gul, Cem Yamali, Gulsen Gunesacar, Hiroshi Sakagami, Noriyuki Okudaira, Yoshihiro Uesawa & Hajime Kagaya. (2018) Cytotoxicity, apoptosis, and QSAR studies of phenothiazine derived methoxylated chalcones as anticancer drug candidates. Medicinal Chemistry Research 27:10, pages 2366-2378.
Crossref
Crossref
Kaan Kucukoglu, Mustafa Gul, Halise Inci Gul, Rengul Cetin-Atalay & Bernard Geny. (2018) Cytotoxicities of novel hydrazone compounds with pyrrolidine moiety: inhibition of mitochondrial respiration may be a possible mechanism of action for the cytotoxicity of new hydrazones. Medicinal Chemistry Research 27:9, pages 2116-2124.
Crossref
Crossref
Claudiu T. Supuran, Vincenzo Alterio, Anna Di Fiore, Katia D’ Ambrosio, Fabrizio Carta, Simona Maria Monti & Giuseppina De Simone. (2018) Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one. Medicinal Research Reviews 38:6, pages 1799-1836.
Crossref
Crossref
Halise Inci Gul, Cem Yamali, Merve Bulbuller, Petek Ballar Kirmizibayrak, Mustafa Gul, Andrea Angeli, Silvia Bua & Claudiu T. Supuran. (2018) Anticancer effects of new dibenzenesulfonamides by inducing apoptosis and autophagy pathways and their carbonic anhydrase inhibitory effects on hCA I, hCA II, hCA IX, hCA XII isoenzymes. Bioorganic Chemistry 78, pages 290-297.
Crossref
Crossref
Gamal Badr, Halise Inci Gul, Cem Yamali, Amal A.M. Mohamed, Badr M. Badr, Mustafa Gul, Ahmad Abo Markeb & Nagwa Abo El-Maali. (2018) Curcumin analogue 1,5-bis(4-hydroxy-3-((4-methylpiperazin-1-yl)methyl)phenyl)penta-1,4-dien-3-one mediates growth arrest and apoptosis by targeting the PI3K/AKT/mTOR and PKC-theta signaling pathways in human breast carcinoma cells. Bioorganic Chemistry 78, pages 46-57.
Crossref
Crossref
Mudasir Nabi Peerzada, Parvez Khan, Kamal Ahmad, Md Imtaiyaz Hassan & Amir Azam. (2018) Synthesis, characterization and biological evaluation of tertiary sulfonamide derivatives of pyridyl-indole based heteroaryl chalcone as potential carbonic anhydrase IX inhibitors and anticancer agents. European Journal of Medicinal Chemistry 155, pages 13-23.
Crossref
Crossref
Cem Yamali, Halise Inci Gul, Abdulilah Ece, Parham Taslimi & Ilhami Gulcin. (2018)
Synthesis, molecular modeling, and biological evaluation of 4-[5-aryl-3-(thiophen-2-yl)-4,5-dihydro-1
H
-pyrazol-1-yl] benzenesulfonamides toward acetylcholinesterase, carbonic anhydrase I and II enzymes
. Chemical Biology & Drug Design 91:4, pages 854-866.
Crossref
Crossref
Halise Inci Gul, Cem Yamali, Hiroshi Sakagami, Andrea Angeli, Janis Leitans, Andris Kazaks, Kaspars Tars, Dilan Ozmen Ozgun & Claudiu T. Supuran. (2018) New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors. Bioorganic Chemistry 77, pages 411-419.
Crossref
Crossref
Cem Yamali, Dilan Ozmen Ozgun, Halise Inci Gul, Hiroshi Sakagami, Cavit Kazaz & Noriyuki Okudaira. (2017) Synthesis and structure elucidation of 1-(2,5/3,5-difluorophenyl)-3-(2,3/2,4/2,5/3,4-dimethoxyphenyl)-2-propen-1-ones as anticancer agents. Medicinal Chemistry Research 26:9, pages 2015-2023.
Crossref
Crossref