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COPD: Journal of Chronic Obstructive Pulmonary Disease Volume 14, 2017 - Issue 3
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Original Research

Resting Physiological Correlates of Reduced Exercise Capacity in Smokers with Mild Airway Obstruction

Amany F. ElbehairyDepartment of Medicine, Respiratory Investigation Unit, Queen's University and Kingston General Hospital, Kingston, ON, Canada;Department of Chest Diseases, Faculty of Medicine, Alexandria University, Alexandria, Egypt
, MD, PhD,
Azmy FaisalFaculty of Physical Education for Men, Alexandria University, Alexandria, Egypt;School of Health Sport and Bioscience, University of East London, United Kingdom
, PhD,
Jordan A. GuenetteDepartment of Physical Therapy and UBC Centre for Heart Lung Innovation, University of British Columbia and St. Paul's Hospital, Vancouver, BC, Canada
, PhD,
Dennis JensenDepartment of Kinesiology & Physical Education, McGill University, Montreal, QC, Canada
, PhD,
Katherine A. WebbDepartment of Medicine, Respiratory Investigation Unit, Queen's University and Kingston General Hospital, Kingston, ON, Canada
, MSc,
Rashid AhmedCollege of Nursing and Professional Disciplines, University of North Dakota, Grand Forks, North Dakota, United States
, PhD,
J. Alberto NederDepartment of Medicine, Respiratory Investigation Unit, Queen's University and Kingston General Hospital, Kingston, ON, Canada
, MD, PhD,
Denis E. O'DonnellDepartment of Medicine, Respiratory Investigation Unit, Queen's University and Kingston General Hospital, Kingston, ON, CanadaCorrespondence[email protected]
, MD & on behalf of Canadian Respiratory Research Network (CRRN) show all
Pages 267-275 | Received 11 Oct 2016, Accepted 06 Jan 2017, Published online: 03 Apr 2017

Citations (25)

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Read on this site (5)

Amany F. Elbehairy, Sandra G. Vincent, Devin B. Phillips, Matthew D. James, Jenna Veugen, Grace Parraga, Denis E. O’Donnell & J. Alberto Neder. (2023) Pulmonary Vascular Volume by Quantitative CT in Dyspneic Smokers with Minor Emphysema. COPD: Journal of Chronic Obstructive Pulmonary Disease 20:1, pages 135-143.
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Matthew D. James, Devin B. Phillips, Amany F. Elbehairy, Kathryn M. Milne, Sandra G. Vincent, Nicolle J. Domnik, Juan P. de Torres, J. Alberto Neder & Denis E. O’Donnell. (2021) Mechanisms of Exertional Dyspnea in Patients with Mild COPD and a Low Resting DLCO . COPD: Journal of Chronic Obstructive Pulmonary Disease 18:5, pages 501-510.
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J. Alberto Neder, Juan P. de Torres & Denis E. O’Donnell. (2021) Recent Advances in the Physiological Assessment of Dyspneic Patients with Mild COPD. COPD: Journal of Chronic Obstructive Pulmonary Disease 18:3, pages 374-384.
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Alan S Bell, Philip J Lawrence, Dave Singh & Alexander Horsley. (2018) Feasibility and challenges of using multiple breath washout in COPD. International Journal of Chronic Obstructive Pulmonary Disease 13, pages 2113-2119.
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Amany F. Elbehairy, Grace Parraga, Katherine A. Webb, J Alberto Neder & Denis E. O’Donnell. (2017) Mild chronic obstructive pulmonary disease: why spirometry is not sufficient!. Expert Review of Respiratory Medicine 11:7, pages 549-563.
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Articles from other publishers (20)

D. Shlomi, T. Beck, R. Reuveny & M.J. Segel. (2023) Prediction of exercise respiratory limitation from pulmonary function tests. Pulmonology.
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Devin B. Phillips, Matthew D. James, Conor D. O’Donnell, Sandra G. Vincent, Katherine A. Webb, Juan P. de-Torres, J. Alberto Neder & Denis E. O’Donnell. (2022) Physiological predictors of morbidity and mortality in COPD: the relative importance of reduced inspiratory capacity and inspiratory muscle strength. Journal of Applied Physiology 133:3, pages 679-688.
Crossref
Devin B. PhillipsAmany F. Elbehairy, Matthew D. JamesSandra G. VincentKathryn M. MilneJuan P. de-TorresJ. Alberto NederMiranda KirbyDennis JensenMichael K. SticklandJordan A. GuenetteBenjamin M. Smith, Shawn D. Aaron, Wan C. TanJean Bourbeau, Denis E. O’Donnell, Jonathon Samet, Milo Puhan, James C. Hogg, Qutayba Hamid, Dany Doiron, Palmina Mancino, Pei-Zhi Li, Zhi Song, Yvan Fortier, Kenneth Chapman, Patricia McClean, Jane Duke, Andrea S. Gershon, Teresa Toh, Mohsen Sadatsafavi, Don Sin, J. Mark Fitzgerald, Jeremy Road, Christine Lo, Sarah Cheng, Elena Un, Michael Cheng, Cynthia Fung, Faize Faroon, Olga Radivojevic, Sally Chung, Carl Zou, Rena Choi, Joe Comeau, Harvey Coxson, Miranda Kirby, Jonathon Leipsic, Cameron Hague, Brandie Walker, Curtis Dumonceaux, Paul Hernandez, Scott Fulton, Kathy Vandemheen, Matthew McNeil, Kate Whelan, Francois Maltais, Cynthia Brouillard, Darcy Marciniuk, Ron Clemens & Janet Baran. (2022) Impaired Ventilatory Efficiency, Dyspnea, and Exercise Intolerance in Chronic Obstructive Pulmonary Disease: Results from the CanCOLD Study. American Journal of Respiratory and Critical Care Medicine 205:12, pages 1391-1402.
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Takudzwa Mkorombindo & Mark T. Dransfield. (2022) Pre-chronic obstructive pulmonary disease: a pathophysiologic process or an opinion term?. Current Opinion in Pulmonary Medicine 28:2, pages 109-114.
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J. Alberto Neder, Danilo C. Berton, Devin B. Phillips & Denis E. O'Donnell. (2021) Exertional ventilation/carbon dioxide output relationship in COPD: from physiological mechanisms to clinical applications. European Respiratory Review 30:161, pages 200190.
Crossref
J. Alberto Neder, Juan Pablo de-Torres & Denis E. O’Donnell. (2021) Exposing Pre–Chronic Obstructive Pulmonary Disease: When Physiology Matters!. American Journal of Respiratory and Critical Care Medicine 204:1, pages 110-111.
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Thibaud Soumagne, Alicia Guillien, Nicolas Roche, Jean-Charles Dalphin & Bruno Degano. (2020) Never-smokers with occupational COPD have better exercise capacities and ventilatory efficiency than matched smokers with COPD. Journal of Applied Physiology 129:6, pages 1257-1266.
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Devin B. Phillips, Sophie É. Collins & Michael K. Stickland. (2020) Measurement and Interpretation of Exercise Ventilatory Efficiency. Frontiers in Physiology 11.
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Aparna Balasubramanian, Neil R. MacIntyre, Robert J. Henderson, Robert L. Jensen, Gregory Kinney, William W. Stringer, Craig P. Hersh, Russell P. Bowler, Richard Casaburi, MeiLan K. Han, Janos Porszasz, R. Graham Barr, Barry J. Make, Robert A. Wise & Meredith C. McCormack. (2019) Diffusing Capacity of Carbon Monoxide in Assessment of COPD. Chest 156:6, pages 1111-1119.
Crossref
Amany F. Elbehairy, Conor D. O'Donnell, Asmaa Abd Elhameed, Sandra G. Vincent, Kathryn M. Milne, Matthew D. James, Katherine A. Webb, J. Alberto Neder & Denis E. O’Donnell. (2019) Low resting diffusion capacity, dyspnea, and exercise intolerance in chronic obstructive pulmonary disease. Journal of Applied Physiology 127:4, pages 1107-1116.
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Paulo de Tarso Muller, Gisele Walter Barbosa, Denis E. O’Donnell & J Alberto Neder. (2019) Cardiopulmonary and Muscular Interactions: Potential Implications for Exercise (In)tolerance in Symptomatic Smokers Without Chronic Obstructive Pulmonary Disease. Frontiers in Physiology 10.
Crossref
Denis E. O’Donnell, Matthew D. James, Kathryn M. Milne & J. Alberto Neder. (2019) The Pathophysiology of Dyspnea and Exercise Intolerance in Chronic Obstructive Pulmonary Disease. Clinics in Chest Medicine 40:2, pages 343-366.
Crossref
J. Alberto Neder, Danilo C. Berton, Paulo T. Muller & Denis E. O’Donnell. (2019) Incorporating Lung Diffusing Capacity for Carbon Monoxide in Clinical Decision Making in Chest Medicine. Clinics in Chest Medicine 40:2, pages 285-305.
Crossref
Pierantonio Laveneziana & Paolo Palange. 2019. Exercise and Sports Pulmonology. Exercise and Sports Pulmonology 71 87 .
Denis E. O'Donnell, Amany F. Elbehairy, Nicolle J. Domnik, Sandra Vincent, Jordan A. Guenette, Katherine A. Webb & J. Alberto Neder. 2018. Clinical Exercise Testing. Clinical Exercise Testing 107 127 .
Amany F. Elbehairy, Katherine A. Webb, Pierantonio Laveneziana, Nicolle J. Domnik, J. Alberto Neder & Denis E. O’Donnell. (2018) Acute bronchodilator therapy does not reduce wasted ventilation during exercise in COPD. Respiratory Physiology & Neurobiology 252-253, pages 64-71.
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Mehrdad Arjomandi, Siyang Zeng, Jeroen Geerts, Rachel K Stiner, Bruce Bos, Ian van Koeverden, Jason Keene, Brett Elicker, Paul D Blanc & Warren M Gold. (2018) Lung volumes identify an at-risk group in persons with prolonged secondhand tobacco smoke exposure but without overt airflow obstruction. BMJ Open Respiratory Research 5:1, pages e000284.
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Joel T. Zelt, Joshua H. Jones, Daniel M. Hirai, Trevor J. King, Danilo C. Berton, Kyra E. Pyke, Denis E. O'Donnell & J. Alberto Neder. (2018) Systemic vascular dysfunction is associated with emphysema burden in mild COPD. Respiratory Medicine 136, pages 29-36.
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Helgo Magnussen, Marco Canepa, Peter Emilio Zambito, Vito Brusasco, Thomas Meinertz & Stephan Rosenkranz. (2017) What can we learn from pulmonary function testing in heart failure?. European Journal of Heart Failure 19:10, pages 1222-1229.
Crossref
J. Alberto Neder, Danilo C. Berton, Paulo de Tarso Müller, Amany F. Elbehairy, Alcides Rocha, Paolo Palange & Denis E. O’Donnell. (2017) Ventilatory Inefficiency and Exertional Dyspnea in Early Chronic Obstructive Pulmonary Disease. Annals of the American Thoracic Society 14:Supplement_1, pages S22-S29.
Crossref

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