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Clinical and Experimental Optometry Volume 98, 2015 - Issue 1
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Review

Biomechanical properties of the keratoconic cornea: a review

Hans R VellaraDepartment of Ophthalmology, New Zealand National Eye Centre, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand,
, BOptom &
Dipika V PatelDepartment of Ophthalmology, New Zealand National Eye Centre, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand,
, PhD MRCOphth
Pages 31-38 | Received 29 May 2014, Accepted 21 Jun 2014, Published online: 15 Apr 2021

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Samantha M. Bradford, Donald J. Brown, Tibor Juhasz, Eric Mikula & James V. Jester. (2016) Nonlinear optical corneal collagen crosslinking of ex vivo rabbit eyes. Journal of Cataract and Refractive Surgery 42:11, pages 1660-1665.
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Charles N. J. McGhee, Bia Z. Kim & Peter J. Wilson. (2015) Contemporary Treatment Paradigms in Keratoconus. Cornea 34:Supplement 10, pages S16-S23.
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