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DNA Methylation Inhibitor 5-Aza-2′-Deoxycytidine Induces Reversible Genome-Wide DNA Damage That Is Distinctly Influenced by DNA Methyltransferases 1 and 3B

Stela S. PaliiDepartment of Biochemistry and Molecular Biology and University of Florida Shands Cancer Center Program in Cancer Genetics, Epigenetics and Tumor Virology, University of Florida, Box 100245, Gainesville, Florida32610
,
Beth O. Van EmburghDepartment of Biochemistry and Molecular Biology and University of Florida Shands Cancer Center Program in Cancer Genetics, Epigenetics and Tumor Virology, University of Florida, Box 100245, Gainesville, Florida32610
,
Umesh T. SankpalDepartment of Biochemistry and Molecular Biology and University of Florida Shands Cancer Center Program in Cancer Genetics, Epigenetics and Tumor Virology, University of Florida, Box 100245, Gainesville, Florida32610
,
Kevin D. BrownDepartment of Biochemistry and Molecular Biology and University of Florida Shands Cancer Center Program in Cancer Genetics, Epigenetics and Tumor Virology, University of Florida, Box 100245, Gainesville, Florida32610
&
Keith D. RobertsonDepartment of Biochemistry and Molecular Biology and University of Florida Shands Cancer Center Program in Cancer Genetics, Epigenetics and Tumor Virology, University of Florida, Box 100245, Gainesville, Florida32610Correspondence[email protected]
Pages 752-771 | Received 02 Oct 2007, Accepted 25 Oct 2007, Published online: 27 Mar 2023

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