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Nucleocytoplasmic Communication

Evidence for Distinct Substrate Specificities of Importin α Family Members in Nuclear Protein Import

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Pages 7782-7791 | Received 03 Mar 1999, Accepted 03 Aug 1999, Published online: 28 Mar 2023

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Crossref
Birgit Cabot & Ryan A Cabot. (2018) Chromatin remodeling in mammalian embryos. Reproduction 155:3, pages R147-R158.
Crossref
Katinka Döhner, Ana Ramos-Nascimento, Dagmara Bialy, Fenja Anderson, Ana Hickford-Martinez, Franziska Rother, Thalea Koithan, Kathrin Rudolph, Anna Buch, Ute Prank, Anne Binz, Stefanie Hügel, Robert Jan Lebbink, Rob C. Hoeben, Enno Hartmann, Michael Bader, Rudolf Bauerfeind & Beate Sodeik. (2018) Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons. PLOS Pathogens 14:1, pages e1006823.
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Natália E. Bernardes, Agnes A.S. Takeda, Thiago R. Dreyer, Fernanda B. Cupertino, Stela Virgilio, Nelly Pante, Maria Célia Bertolini & Marcos R.M. Fontes. (2017) Nuclear transport of the Neurospora crassa NIT-2 transcription factor is mediated by importin-α . Biochemical Journal 474:24, pages 4091-4104.
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Rajeshwer S. Sankhala, Ravi K. Lokareddy, Salma Begum, Ruth A. Pumroy, Richard E. Gillilan & Gino Cingolani. (2017) Three-dimensional context rather than NLS amino acid sequence determines importin α subtype specificity for RCC1. Nature Communications 8:1.
Crossref
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Crossref
Noriko Yasuhara & Yoshihiro Yoneda. (2017) Reprint of: Importins in the maintenance and lineage commitment of ES cells. Neurochemistry International 106, pages 14-23.
Crossref
Anthony A. Stephenson, David J. Taggart & Zucai Suo. (2017) Noncatalytic, N-terminal Domains of DNA Polymerase Lambda Affect Its Cellular Localization and DNA Damage Response. Chemical Research in Toxicology 30:5, pages 1240-1249.
Crossref
Noriko Yasuhara & Yoshihiro Yoneda. (2017) Importins in the maintenance and lineage commitment of ES cells. Neurochemistry International 105, pages 32-41.
Crossref
Benjamin M. Laitman, John N. Mariani, Chi Zhang, Setsu Sawai & Gareth R. John. (2017) Karyopherin Alpha Proteins Regulate Oligodendrocyte Differentiation. PLOS ONE 12:1, pages e0170477.
Crossref
Elisa M. Vuorinen, Nina K. Rajala, Hanna E. Rauhala, Anssi T. Nurminen, Vesa P. Hytönen & Anne Kallioniemi. (2017) Search for KPNA7 cargo proteins in human cells reveals MVP and ZNF414 as novel regulators of cancer cell growth. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1863:1, pages 211-219.
Crossref
Khwansiri Ninpan, Ornpreya Suptawiwat, Chompunuch Boonarkart, Peerayuht Phuangphung, Sakda Sathirareuangchai, Mongkol Uiprasertkul & Prasert Auewarakul. (2016) Expression of importin-α isoforms in human nasal mucosa: implication for adaptation of avian influenza A viruses to human host. Virology Journal 13:1.
Crossref
Yan Xu, Jie Chen, Lan Xiao, Hee Kyoung Chung, Yuan Zhang, Joseph C. Robinson, Jaladanki N. Rao & Jian-Ying Wang. (2016) Transcriptional regulation of importin-α 1 by JunD modulates subcellular localization of RNA-binding protein HuR in intestinal epithelial cells . American Journal of Physiology-Cell Physiology 311:6, pages C874-C883.
Crossref
Hyo-Jung Choo, Alicia Cutler, Franziska Rother, Michael Bader & Grace K. Pavlath. (2016) Karyopherin Alpha 1 Regulates Satellite Cell Proliferation and Survival by Modulating Nuclear Import. Stem Cells 34:11, pages 2784-2797.
Crossref
Hyeon Gyu Seo, Han Byeol Kim, Min Jueng Kang, Joo Hwan Ryum, Eugene C. Yi & Jin Won Cho. (2016) Identification of the nuclear localisation signal of O-GlcNAc transferase and its nuclear import regulation. Scientific Reports 6:1.
Crossref
Jose M. Pimiento, Kevin G. Neill, Evita Henderson-Jackson, Steven A. Eschrich, Dung-Tsa Chen, Kazim Husain, David Shibata, Domenico Coppola & Mokenge P. Malafa. (2016) Knockdown of CSE1L Gene in Colorectal Cancer Reduces Tumorigenesis in Vitro. The American Journal of Pathology 186:10, pages 2761-2768.
Crossref
Jihui Duan, Zhiqin Tang, Hong Mu & Guojun Zhang. (2016) Nuclear import of prototype foamy virus transactivator Bel1 is mediated by KPNA1, KPNA6 and KPNA7. International Journal of Molecular Medicine 38:2, pages 399-406.
Crossref
Ruth E. Watkinson & Benhur Lee. (2016) Nipah virus matrix protein: expert hacker of cellular machines. FEBS Letters 590:15, pages 2494-2511.
Crossref
Mary Christie, Chiung-Wen Chang, Gergely Róna, Kate M. Smith, Alastair G. Stewart, Agnes A.S. Takeda, Marcos R.M. Fontes, Murray Stewart, Beáta G. Vértessy, Jade K. Forwood & Bostjan Kobe. (2016) Structural Biology and Regulation of Protein Import into the Nucleus. Journal of Molecular Biology 428:10, pages 2060-2090.
Crossref
Vincent R. Roggero, Jibo Zhang, Laura E. Parente, Yazdi Doshi, Rose C. Dziedzic, Emma L. McGregor, Arev D. Varjabedian, Sara E. Schad, Cornelius Bondzi & Lizabeth A. Allison. (2016) Nuclear import of the thyroid hormone receptor α1 is mediated by importin 7, importin β1, and adaptor importin α1. Molecular and Cellular Endocrinology 419, pages 185-197.
Crossref
Stephen A. Adam. 2016. The Nuclear Envelope. The Nuclear Envelope 479 487 .
R Shrestha, H Tatsukawa, R Shrestha, N Ishibashi, T Matsuura, H Kagechika, S Kose, K Hitomi, N Imamoto & S Kojima. (2015) Molecular mechanism by which acyclic retinoid induces nuclear localization of transglutaminase 2 in human hepatocellular carcinoma cells. Cell Death & Disease 6:12, pages e2002-e2002.
Crossref
Aihua Dai, Xiaorong Liu, Yu Zhang, Lijian Han, Liang Zhu, Haidan Ni, Rongrong Chen & Maohong Cao. (2015) RETRACTED ARTICLE: Up-Regulation of KPNB1 Involves in Neuronal Apoptosis Following Intracerebral Hemorrhage in Adult Rats. Neurochemical Research 40:11, pages 2177-2187.
Crossref
Nam-Hee Kim, Tetsuro Yoshimaru, Yi-An Chen, Taisuke Matsuo, Masato Komatsu, Yasuo Miyoshi, Eiji Tanaka, Mitsunori Sasa, Kenji Mizuguchi & Toyomasa Katagiri. (2015) BIG3 Inhibits the Estrogen-Dependent Nuclear Translocation of PHB2 via Multiple Karyopherin-Alpha Proteins in Breast Cancer Cells. PLOS ONE 10:6, pages e0127707.
Crossref
Linlin Yang, Baoying Hu, Yixin Zhang, Songlin Qiang, Jin Cai, Wei Huang, Chen Gong, Tingting Zhang, ShuSen Zhang, Pan Xu, Xuming Wu & Jibin Liu. (2015) Suppression of the nuclear transporter-KPNβ1 expression inhibits tumor proliferation in hepatocellular carcinoma. Medical Oncology 32:4.
Crossref
Ruth A. PumroyGino Cingolani. (2015) Diversification of importin-α isoforms in cellular trafficking and disease states. Biochemical Journal 466:1, pages 13-28.
Crossref
Ruth A. Pumroy, Song Ke, Darren J. Hart, Ulrich Zachariae & Gino Cingolani. (2015) Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin α Isoforms 3 and 7. Structure 23:2, pages 374-384.
Crossref
Yanfang Li, Ki-Eun Park & Ryan A. Cabot. (2015) Dynamic changes in nuclear import of a nuclear localisation signal-bearing substrate in 8-cell stage porcine embryos. Reproduction, Fertility and Development 27:2, pages 385.
Crossref
Andrei Surguchov. 2015. 103 169 .
Lisanework E. Ayalew, Amit Gaba, Pankaj Kumar & Suresh K. Tikoo. (2014) Conserved regions of bovine adenovirus-3 pVIII contain functional domains involved in nuclear localization and packaging in mature infectious virions. Journal of General Virology 95:8, pages 1743-1754.
Crossref
Vikas Kulshreshtha, Lisanework E. Ayalew, Azharul Islam & Suresh K. Tikoo. (2014) Conserved Arginines of Bovine Adenovirus-3 33K Protein Are Important for Transportin-3 Mediated Transport and Virus Replication. PLoS ONE 9:7, pages e101216.
Crossref
Stefanie Hügel, Reinhard Depping, Gunnar Dittmar, Franziska Rother, Ryan Cabot, Matthias D. Sury, Enno Hartmann & Michael Bader. (2014) Identification of Importin α 7 Specific Transport Cargoes Using a Proteomic Screening Approach. Molecular & Cellular Proteomics 13:5, pages 1286-1298.
Crossref
Sarah C. Nicolson & R. Jude Samulski. (2014) Recombinant Adeno-Associated Virus Utilizes Host Cell Nuclear Import Machinery To Enter the Nucleus. Journal of Virology 88:8, pages 4132-4144.
Crossref
Xinghui Sun, Alan Sit & Mark W. Feinberg. (2014) Role of miR-181 family in regulating vascular inflammation and immunity. Trends in Cardiovascular Medicine 24:3, pages 105-112.
Crossref
Ankita Aggarwal & Devendra K. Agrawal. (2014) Importins and Exportins Regulating Allergic Immune Responses. Mediators of Inflammation 2014, pages 1-14.
Crossref
Saijo Thomas, Jagdish Rai, Lijo John, Stephan Schaefer, Brigitte M Pützer & Ottmar Herchenröder. (2013) Chikungunya virus capsid protein contains nuclear import and export signals. Virology Journal 10:1.
Crossref
Xiao-Lei Li, Lan-Ling Jia, Mu-Mu Shi, Xin Li, Zhong-Hua Li, Hui-Feng Li, En-Hua Wang & Xin-Shan Jia. (2013) Downregulation of KPNA2 in non-small-cell lung cancer is associated with Oct4 expression. Journal of Translational Medicine 11:1.
Crossref
Peter Kitzmann, Jonas Schwirz, Christian Schmitt-Engel & Gregor Bucher. (2013) RNAi phenotypes are influenced by the genetic background of the injected strain. BMC Genomics 14:1.
Crossref
Xinghui Sun, Nathan Belkin & Mark W. Feinberg. (2013) Endothelial MicroRNAs and Atherosclerosis. Current Atherosclerosis Reports 15:12.
Crossref
Jozef Zienkiewicz, Amy Armitage & Jacek Hawiger. (2013) Targeting Nuclear Import Shuttles, Importins/Karyopherins alpha by a Peptide Mimicking the NFκB1/p50 Nuclear Localization Sequence. Journal of the American Heart Association 2:5.
Crossref
Peizhou Liang, Haiyan Zhang, Guoxin Wang, Suping Li, Shujie Cong, Yingyun Luo & Biliang Zhang. (2013) KPNB1 , XPO7 and IPO8 Mediate the Translocation ofNF-κB/p65 into the Nucleus . Traffic, pages n/a-n/a.
Crossref
Makoto Kimura, Nobuaki Okumura, Shingo Kose, Toshifumi Takao & Naoko Imamoto. (2013) Identification of Cargo Proteins Specific for Importin-β with Importin-α Applying a Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC)-based in Vitro Transport System*. Journal of Biological Chemistry 288:34, pages 24540-24549.
Crossref
Noriko Yasuhara, Ryosuke Yamagishi, Yoshiyuki Arai, Rashid Mehmood, Chihiro Kimoto, Toshiharu Fujita, Kenichi Touma, Azumi Kaneko, Yasunao Kamikawa, Tetsuji Moriyama, Toshio Yanagida, Hiroki Kaneko & Yoshihiro Yoneda. (2013) Importin Alpha Subtypes Determine Differential Transcription Factor Localization in Embryonic Stem Cells Maintenance. Developmental Cell 26:2, pages 123-135.
Crossref
Hicham Mahboubi, Evangeline Seganathy, Dekun Kong & Ursula Stochaj. (2013) Identification of Novel Stress Granule Components That Are Involved in Nuclear Transport. PLoS ONE 8:6, pages e68356.
Crossref
Chelsi J. Snow, Ashraf Dar, Anindya Dutta, Ralph H. Kehlenbach & Bryce M. Paschal. (2013) Defective nuclear import of Tpr in Progeria reflects the Ran sensitivity of large cargo transport. Journal of Cell Biology 201:4, pages 541-557.
Crossref
Martin Bierbaum & Philippe I.H. Bastiaens. (2013) Cell Cycle-Dependent Binding Modes of the Ran Exchange Factor RCC1 to Chromatin. Biophysical Journal 104:8, pages 1642-1651.
Crossref
Ha Youn Shin & Nancy C. Reich. (2013) Dynamic Trafficking of STAT5 Depends on an Unconventional Nuclear Localization Signal. Journal of Cell Science.
Crossref
Kosuke Okazaki, Naomi Nakayama, Yuko Nariai, Kentaro Nakayama, Kohji Miyazaki, Riruke Maruyama, Hiroaki Kato, Shunichi Kosugi, Takeshi Urano & Gyosuke Sakashita. (2012) Nuclear localization signal in a cancer-related transcriptional regulator protein NAC1. Carcinogenesis 33:10, pages 1854-1862.
Crossref
Carolyn P. Paterson, Lisanework E. Ayalew & Suresh K. Tikoo. (2012) Mapping of nuclear import signal and importin α3 binding regions of 52K protein of bovine adenovirus-3. Virology 432:1, pages 63-72.
Crossref
Oliver Taltynov, Belete A. Desimmie, Jonas Demeulemeester, Frauke Christ & Zeger Debyser. (2012) Cellular Cofactors of Lentiviral Integrase: From Target Validation to Drug Discovery. Molecular Biology International 2012, pages 1-16.
Crossref
Kallie B. Foust, Yanfang Li, Kieun Park, Xin Wang, Shihong Liu & Ryan A. Cabot. (2012) The polycomb group protein EED varies in its ability to access the nucleus in porcine oocytes and cleavage stage embryos. Animal Reproduction Science 133:3-4, pages 198-204.
Crossref
Ki-Eun Park, H. Dorota Inerowicz, Xin Wang, Yanfang Li, Stephanie Koser & Ryan A. Cabot. (2012) Identification of Karyopherin α1 and α7 Interacting Proteins in Porcine Tissue. PLoS ONE 7:6, pages e38990.
Crossref
Yoichi Miyamoto, Peter R. Boag, Gary R. Hime & Kate L. Loveland. (2012) Regulated nucleocytoplasmic transport during gametogenesis. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1819:6, pages 616-630.
Crossref
Xinghui Sun, Basak Icli, Akm Khyrul Wara, Nathan Belkin, Shaolin He, Lester Kobzik, Gary M. Hunninghake, Miguel Pinilla Vera, Timothy S. Blackwell, Rebecca M. Baron & Mark W. Feinberg. (2012) MicroRNA-181b regulates NF-κB–mediated vascular inflammation. Journal of Clinical Investigation.
Crossref
Yoshinari Yasuda, Yoichi Miyamoto, Tomoko Yamashiro, Munehiro Asally, Ayumi Masui, Chin Wong, Kate L Loveland & Yoshihiro Yoneda. (2012) Nuclear retention of importin α coordinates cell fate through changes in gene expression. The EMBO Journal 31:1, pages 83-94.
Crossref
Erika Virágh, Mátyás Gorjánácz, István Török, Tolga Eichhorn, Sowjanya Kallakuri, Tamás Szlanka, István Kiss & Bernard M Mechler. (2012) Specific Cooperation Between Imp-α2 and Imp-β/Ketel in Spindle Assembly During Drosophila Early Nuclear Divisions . G3 Genes|Genomes|Genetics 2:1, pages 1-14.
Crossref
Ruth A. Pumroy, Jonathan D. Nardozzi, Darren J. Hart, Michael J. Root & Gino Cingolani. (2012) Nucleoporin Nup50 Stabilizes Closed Conformation of Armadillo repeat 10 in Importin α5. Journal of Biological Chemistry 287:3, pages 2022-2031.
Crossref
Xin Wang, Ki-Eun Park, Stephanie Koser, Shihong Liu, Luca Magnani & Ryan A. Cabot. (2012) KPNA7, an oocyte- and embryo-specific karyopherin?subtype, is required for porcine embryo development. Reproduction, Fertility and Development 24:2, pages 382.
Crossref
Rashid Mehmood, Noriko Yasuhara, Masahiro Fukumoto, Souichi Oe, Taro Tachibana & Yoshihiro Yoneda. (2011) Cross-talk between distinct nuclear import pathways enables efficient nuclear import of E47 in conjunction with its partner transcription factors. Molecular Biology of the Cell 22:19, pages 3715-3724.
Crossref
Monica N. Hall, Christine A. Griffin, Adriana Simionescu, Anita H. Corbett & Grace K. Pavlath. (2011) Distinct roles for classical nuclear import receptors in the growth of multinucleated muscle cells. Developmental Biology 357:1, pages 248-258.
Crossref
Joseph Esfandiar Hannon Bozorgmehr. (2011) An ancient frame-shifting event in the highly conserved KPNA gene family has undergone extensive compensation by natural selection in vertebrates. Biosystems 105:3, pages 210-215.
Crossref
Wenduo Ye, Wenbo Lin, Alan M. Tartakoff & Tao Tao. (2011) Karyopherins in nuclear transport of homeodomain proteins during development. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1813:9, pages 1654-1662.
Crossref
Mary Marfori, Andrew Mynott, Jonathan J. Ellis, Ahmed M. Mehdi, Neil F.W. Saunders, Paul M. Curmi, Jade K. Forwood, Mikael Bodén & Bostjan Kobe. (2011) Molecular basis for specificity of nuclear import and prediction of nuclear localization. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1813:9, pages 1562-1577.
Crossref
Kaylen Lott & Gino Cingolani. (2011) The importin β binding domain as a master regulator of nucleocytoplasmic transport. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1813:9, pages 1578-1592.
Crossref
Leda Raptis, Rozanne Arulanandam, Mulu Geletu & James Turkson. (2011) The R(h)oads to Stat3: Stat3 activation by the Rho GTPases. Experimental Cell Research 317:13, pages 1787-1795.
Crossref
Chun‐I. Wang, Chih‐Liang Wang, Chih‐Wei Wang, Chi‐De Chen, Chih‐Ching Wu, Ying Liang, Ying‐Huang Tsai, Yu‐Sun Chang, Jau‐Song Yu & Chia‐Jung Yu. (2010) Importin subunit alpha‐2 is identified as a potential biomarker for non‐small cell lung cancer by integration of the cancer cell secretome and tissue transcriptome. International Journal of Cancer 128:10, pages 2364-2372.
Crossref
Franziska Rother, Tatiana Shmidt, Elena Popova, Alexander Krivokharchenko, Stefanie Hügel, Larissa Vilianovich, Michael Ridders, Katja Tenner, Natalia Alenina, Matthias Köhler, Enno Hartmann & Michael Bader. (2011) Importin α7 Is Essential for Zygotic Genome Activation and Early Mouse Development. PLoS ONE 6:3, pages e18310.
Crossref
Gülsah Gabriel, Karin Klingel, Anna Otte, Swantje Thiele, Ben Hudjetz, Gökhan Arman-Kalcek, Martina Sauter, Tatiana Shmidt, Franziska Rother, Sigrid Baumgarte, Björn Keiner, Enno Hartmann, Michael Bader, George G. Brownlee, Ervin Fodor & Hans-Dieter Klenk. (2011) Differential use of importin-α isoforms governs cell tropism and host adaptation of influenza virus. Nature Communications 2:1.
Crossref
Monica N. Hall, Anita H. Corbett & Grace K. Pavlath. 2011. Myogenesis. Myogenesis 273 302 .
Joshua B Kelley, Ashley M Talley, Adam Spencer, Daniel Gioeli & Bryce M Paschal. (2010) Karyopherin α7 (KPNA7), a divergent member of the importin α family of nuclear import receptors. BMC Cell Biology 11:1.
Crossref
Rafał Pawłowski, Eeva Kaisa Rajakylä, Maria K Vartiainen & Richard Treisman. (2010) An actin-regulated importin α/β-dependent extended bipartite NLS directs nuclear import of MRTF-A. The EMBO Journal 29:20, pages 3448-3458.
Crossref
Zhujun Ao, Kallesh Danappa Jayappa, Binchen Wang, Yingfeng Zheng, Sam Kung, Eric Rassart, Reinhard Depping, Matthias Kohler, Eric A. Cohen & Xiaojian Yao. (2010) Importin α3 Interacts with HIV-1 Integrase and Contributes to HIV-1 Nuclear Import and Replication. Journal of Virology 84:17, pages 8650-8663.
Crossref
Jonathan Nardozzi, Nikola Wenta, Noriko Yasuhara, Uwe Vinkemeier & Gino Cingolani. (2010) Molecular Basis for the Recognition of Phosphorylated STAT1 by Importin α5. Journal of Molecular Biology 402:1, pages 83-100.
Crossref
Kerstin Huenniger, Andreas Krämer, Malle Soom, Iree Chang, Matthias Köhler, Reinhard Depping, Ralph H. Kehlenbach & Christoph Kaether. (2010) Notch1 signaling is mediated by importins alpha 3, 4, and 7. Cellular and Molecular Life Sciences 67:18, pages 3187-3196.
Crossref
Mohanad Mossalam, Andrew S Dixon & Carol S Lim. (2010) Controlling subcellular delivery to optimize therapeutic effect. Therapeutic Delivery 1:1, pages 169-193.
Crossref
Hui-Chen Chen & Nancy C. Reich. (2010) Live Cell Imaging Reveals Continuous STAT6 Nuclear Trafficking. The Journal of Immunology 185:1, pages 64-70.
Crossref
Agnes L. Nishimura, Vera Župunski, Claire Troakes, Claudia Kathe, Pietro Fratta, Michael Howell, Jean–Marc Gallo, Tibor Hortobágyi, Christopher E. Shaw & Boris Rogelj. (2010) Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration. Brain 133:6, pages 1763-1771.
Crossref
Sundy N.Y. Yang, Agnes A.S. Takeda, Marcos R.M. Fontes, Jonathan M. Harris, David A. Jans & Boštjan Kobe. (2010) Probing the Specificity of Binding to the Major Nuclear Localization Sequence-binding Site of Importin-α Using Oriented Peptide Library Screening. Journal of Biological Chemistry 285:26, pages 19935-19946.
Crossref
S. P. Chumakov & V. S. Prassolov. (2010) Organization and regulation of nucleocytoplasmic transport. Molecular Biology 44:2, pages 186-201.
Crossref
Feng-Qian LiAdaobi Mofunanya, Victoria Fischer, Jason HallKen-Ichi Takemaru. (2010) Nuclear-Cytoplasmic Shuttling of Chibby Controls β-Catenin Signaling. Molecular Biology of the Cell 21:2, pages 311-322.
Crossref
Aldo Giudice, Claudio Arra & Maria C. Turco. 2010. Transcription Factors. Transcription Factors 37 74 .
Virginie W Gautier, Lili Gu, Niaobh O'Donoghue, Stephen Pennington, Noreen Sheehy & William W Hall. (2009) In vitro nuclear interactome of the HIV-1 Tat protein. Retrovirology 6:1.
Crossref
Arianne L. Theiss, Aaron K. Jenkins, Ngozi I. Okoro, Jan-Michael A. Klapproth, Didier Merlin & Shanthi V. Sitaraman. (2009) Prohibitin Inhibits Tumor Necrosis Factor alpha–induced Nuclear Factor-kappa B Nuclear Translocation via the Novel Mechanism of Decreasing Importin α3 Expression. Molecular Biology of the Cell 20:20, pages 4412-4423.
Crossref
Amrei Steinhoff, Friederike Katharina Pientka, Sylvia Möckel, Antje Kettelhake, Enno Hartmann, Matthias Köhler & Reinhard Depping. (2009) Cellular oxygen sensing: Importins and exportins are mediators of intracellular localisation of prolyl-4-hydroxylases PHD1 and PHD2. Biochemical and Biophysical Research Communications 387:4, pages 705-711.
Crossref
Mirna N. Chahine & Grant N. Pierce. (2009) Therapeutic Targeting of Nuclear Protein Import in Pathological Cell Conditions. Pharmacological Reviews 61:3, pages 358-372.
Crossref
Stefan Maas & Willemijn M. Gommans. (2009) Identification of a selective nuclear import signal in adenosine deaminases acting on RNA. Nucleic Acids Research 37:17, pages 5822-5829.
Crossref
Christopher F. BaslerGaya K. Amarasinghe. (2009) Evasion of Interferon Responses by Ebola and Marburg Viruses. Journal of Interferon & Cytokine Research 29:9, pages 511-520.
Crossref
Jyothsna Tejomurtula, Kyung-Bon Lee, Swamy K. Tripurani, George W. Smith & Jianbo Yao. (2009) Role of Importin Alpha8, a New Member of the Importin Alpha Family of Nuclear Transport Proteins, in Early Embryonic Development in Cattle1. Biology of Reproduction 81:2, pages 333-342.
Crossref
Noriko Yasuhara, Masahiro Oka & Yoshihiro Yoneda. (2009) The role of the nuclear transport system in cell differentiation. Seminars in Cell & Developmental Biology 20:5, pages 590-599.
Crossref
C. Itman, Y. Miyamoto, J. Young, D.A. Jans & K.L. Loveland. (2009) Nucleocytoplasmic transport as a driver of mammalian gametogenesis. Seminars in Cell & Developmental Biology 20:5, pages 607-619.
Crossref
Stephen A. Adam. (2009) The nuclear transport machinery in Caenorhabditis elegans: A central role in morphogenesis. Seminars in Cell & Developmental Biology 20:5, pages 576-581.
Crossref
Pauline J. van der Watt, Christopher P. Maske, Denver T. Hendricks, M. Iqbal Parker, Lynette Denny, Dhirendra Govender, Michael J. Birrer & Virna D. Leaner. (2009) The Karyopherin proteins, Crm1 and Karyopherin β1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation. International Journal of Cancer 124:8, pages 1829-1840.
Crossref
Cristina Gontan, Thomas Güttler, Erik Engelen, Jeroen Demmers, Maarten Fornerod, Frank G. Grosveld, Dick Tibboel, Dirk Görlich, Raymond A. Poot & Robbert J. Rottier. (2009) Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors. Journal of Cell Biology 185:1, pages 27-34.
Crossref
Xiangyun Lu, Jimin Shao, Hongjuan Li & Yingnian Yu. (2009) Early whole-genome transcriptional response induced by benzo[a]pyrene diol epoxide in a normal human cell line. Genomics 93:4, pages 332-342.
Crossref
Yukiko Horiike, Hideki Kobayashi & Takeshi Sekiguchi. (2008) Ran GTPase guanine nucleotide exchange factor RCC1 is phosphorylated on serine 11 by cdc2 kinase in vitro. Molecular Biology Reports 36:4, pages 717-723.
Crossref
Shunichi Kosugi, Masako Hasebe, Nobutaka Matsumura, Hideaki Takashima, Etsuko Miyamoto-Sato, Masaru Tomita & Hiroshi Yanagawa. (2009) Six Classes of Nuclear Localization Signals Specific to Different Binding Grooves of Importin α. Journal of Biological Chemistry 284:1, pages 478-485.
Crossref
Kwok-On Lai, Dan Wang & Kelsey C. Martin. 2009. Intracellular Traffic and Neurodegenerative Disorders. Intracellular Traffic and Neurodegenerative Disorders 71 85 .
Klaus-Dieter Spindler, Katarzyna Betanńska, Claudia Nieva, Tomasz Gwóźoanna, Joanna Dutko-Gwóźdź, Andrzej Ożyhar & Margarethe Spindler-Barth. 2009. Ecdysone: Structures and Functions. Ecdysone: Structures and Functions 389 409 .
K. Hosokawa, M. Nishi, H. Sakamoto, Y. Tanaka & M. Kawata. (2008) Regional distribution of importin subtype mRNA expression in the nervous system: Study of early postnatal and adult mouse. Neuroscience 157:4, pages 864-877.
Crossref
Koichiro Gen, Sonoko Yamaguchi, Koichi Okuzawa, Hirohiko Kagawa & Md. Samsul Alam. (2008) Novel expression of importin α homologue in marine teleost, Pagrus major. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 151:4, pages 420-427.
Crossref
Andreas Marg, Thomas Meyer, Marc Vigneron & Uwe Vinkemeier. (2008) Microinjected antibodies interfere with protein nucleocytoplasmic shuttling by distinct molecular mechanisms. Cytometry Part A 73A:12, pages 1128-1140.
Crossref
Christopher F. Basler. 2008. Cellular Signaling and Innate Immune Responses to RNA Virus Infections. Cellular Signaling and Innate Immune Responses to RNA Virus Infections 229 246 .
Taro TachibanaNaoko SakaguchiYoichi MiyamotoToshihiro SekimotoYoshihiro YonedaMasayuki Azuma. (2008) Generation and Characterization of a Monoclonal Antibody Against NPI-1 Subfamily of Importin α . Hybridoma 27:4, pages 285-289.
Crossref
Riku Fagerlund, Krister Melén, Xinmin Cao & Ilkka Julkunen. (2008) NF-κB p52, RelB and c-Rel are transported into the nucleus via a subset of importin α molecules. Cellular Signalling 20:8, pages 1442-1451.
Crossref
Sutha Sangiambut, Poonsook Keelapang, John Aaskov, Chunya Puttikhunt, Watchara Kasinrerk, Prida Malasit & Nopporn Sittisombut. (2008) Multiple regions in dengue virus capsid protein contribute to nuclear localization during virus infection. Journal of General Virology 89:5, pages 1254-1264.
Crossref
Melanie Theodore, Yumiko Kawai, Jianqi Yang, Yuliya Kleshchenko, Sekhar P. Reddy, Fernando Villalta & Ifeanyi J. Arinze. (2008) Multiple Nuclear Localization Signals Function in the Nuclear Import of the Transcription Factor Nrf2. Journal of Biological Chemistry 283:14, pages 8984-8994.
Crossref
Cristiana Iosef, Theofanis Gkourasas, Christina Y. H. Jia, Shawn S.-C. Li & Victor K. M. Han. (2008) A Functional Nuclear Localization Signal in Insulin-Like Growth Factor Binding Protein-6 Mediates Its Nuclear Import. Endocrinology 149:3, pages 1214-1226.
Crossref
Fabio Parmeggiani, Riccardo Pellarin, Anders Peter Larsen, Gautham Varadamsetty, Michael T. Stumpp, Oliver Zerbe, Amedeo Caflisch & Andreas Plückthun. (2008) Designed Armadillo Repeat Proteins as General Peptide-Binding Scaffolds: Consensus Design and Computational Optimization of the Hydrophobic Core. Journal of Molecular Biology 376:5, pages 1282-1304.
Crossref
Reinhard Depping, Amrei Steinhoff, Susann G. Schindler, Beate Friedrich, Riku Fagerlund, Eric Metzen, Enno Hartmann & Matthias Köhler. (2008) Nuclear translocation of hypoxia-inducible factors (HIFs): Involvement of the classical importin α/β pathway. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1783:3, pages 394-404.
Crossref
R Ratan, D A Mason, B Sinnot, D S Goldfarb & R J Fleming. (2008) Drosophila Importin α1 Performs Paralog-Specific Functions Essential For Gametogenesis. Genetics 178:2, pages 839-850.
Crossref
Percy Luk Yeung, Liuh-Yow Chen, Shih-Chieh Tsai, Aihua Zhang & J. Don Chen. (2008) Daxx contains two nuclear localization signals and interacts with importin α3. Journal of Cellular Biochemistry 103:2, pages 456-470.
Crossref
Tongtong ZouLan LiuJaladanki N. RaoBernard S. MarasaJie ChenLan XiaoHuiping ZhouMyriam GorospeJian-Ying Wang. (2007) Polyamines modulate the subcellular localization of RNA-binding protein HuR through AMP-activated protein kinase-regulated phosphorylation and acetylation of importin α1. Biochemical Journal 409:2, pages 389-398.
Crossref
St. Patrick Reid, Charalampos Valmas, Osvaldo Martinez, Freddy Mauricio Sanchez & Christopher F. Basler. (2007) Ebola Virus VP24 Proteins Inhibit the Interaction of NPI-1 Subfamily Karyopherin α Proteins with Activated STAT1. Journal of Virology 81:24, pages 13469-13477.
Crossref
Laura J. TerryEric B. ShowsSusan R. Wente. (2007) Crossing the Nuclear Envelope: Hierarchical Regulation of Nucleocytoplasmic Transport. Science 318:5855, pages 1412-1416.
Crossref
Fiona E. Hood & Paul R. Clarke. (2007) RCC1 isoforms differ in their affinity for chromatin, molecular interactions and regulation by phosphorylation. Journal of Cell Science 120:19, pages 3436-3445.
Crossref
Youhei Saito, Nobuyuki Yamagishi & Takumi Hatayama. (2007) Different localization of Hsp105 family proteins in mammalian cells. Experimental Cell Research 313:17, pages 3707-3717.
Crossref
Patricia Buse, Anita C. Maiyar, Kim L. Failor, Susan Tran, Meredith L.L. Leong & Gary L. Firestone. (2007) The stimulus-dependent co-localization of serum- and glucocorticoid-regulated protein kinase (Sgk) and Erk/MAPK in mammary tumor cells involves the mutual interaction with the importin-alpha nuclear import protein. Experimental Cell Research 313:15, pages 3261-3275.
Crossref
Cathryn A. Hogarth, David A. Jans & Kate L. Loveland. (2007) Subcellular distribution of importins correlates with germ cell maturation. Developmental Dynamics 236:8, pages 2311-2320.
Crossref
Dianbo Qu, Yi Zhang, Jing Ma, Ke Guo, Rong Li, Yijun Yin, Xinmin Cao & David S Park. (2007) The nuclear localization of SET mediated by imp?3/imp? attenuates its cytosolic toxicity in neurons. Journal of Neurochemistry 0:0, pages 070702072507005-???.
Crossref
Krister Melén, Leena Kinnunen, Riku Fagerlund, Niina Ikonen, Karen Y. Twu, Robert M. Krug & Ilkka Julkunen. (2007) Nuclear and Nucleolar Targeting of Influenza A Virus NS1 Protein: Striking Differences between Different Virus Subtypes. Journal of Virology 81:11, pages 5995-6006.
Crossref
Noriko Umegaki, Katsuto Tamai, Hajime Nakano, Ryuta Moritsugu, Takehiko Yamazaki, Katsumi Hanada, Ichiro Katayama & Yasufumi Kaneda. (2007) Differential Regulation of Karyopherin α 2 Expression by TGF-β1 and IFN-γ in Normal Human Epidermal Keratinocytes: Evident Contribution of KPNA2 for Nuclear Translocation of IRF-1. Journal of Investigative Dermatology 127:6, pages 1456-1464.
Crossref
Yuko Nitahara-Kasahara, Masakazu Kamata, Takuya Yamamoto, Xianfeng Zhang, Yoichi Miyamoto, Koho Muneta, Sayuki Iijima, Yoshihiro Yoneda, Yasuko Tsunetsugu-Yokota & Yoko Aida. (2007) Novel Nuclear Import of Vpr Promoted by Importin α Is Crucial for Human Immunodeficiency Virus Type 1 Replication in Macrophages. Journal of Virology 81:10, pages 5284-5293.
Crossref
Paul R. Clarke. (2007) Anchoring RCC1 by the tail. Nature Cell Biology 9:5, pages 485-487.
Crossref
Thirumala-Devi Kanneganti, Xiaodong Bai, Chi-Wei Tsai, Joe Win, Tea Meulia, Michael Goodin, Sophien Kamoun & Saskia A. Hogenhout. (2007) A functional genetic assay for nuclear trafficking in plants. The Plant Journal 50:1, pages 149-158.
Crossref
Nina Østergaard Knudsen, Finn Cilius Nielsen, Lena Vinther, Ronni Bertelsen, Steen Holten-Andersen, Sascha Emilie Liberti, Robert Hofstra, Krista Kooi & Lene Juel Rasmussen. (2007) Nuclear localization of human DNA mismatch repair protein exonuclease 1 (hEXO1). Nucleic Acids Research 35:8, pages 2609-2619.
Crossref
Nickett S. Donaldson, Yasmin Daniel, Kevin F. Kelly, Monica Graham & Juliet M. Daniel. (2007) Nuclear trafficking of the POZ-ZF protein Znf131. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1773:4, pages 546-555.
Crossref
Xue-Lin Bian, Germán Rosas-Acosta, Yu-Chieh Wu & Van G. Wilson. (2007) Nuclear Import of Bovine Papillomavirus Type 1 E1 Protein Is Mediated by Multiple Alpha Importins and Is Negatively Regulated by Phosphorylation near a Nuclear Localization Signal. Journal of Virology 81:6, pages 2899-2908.
Crossref
Shelagh E.L. Mirski, Kathryn E. Sparks, Beate Friedrich, Matthias Köhler, Yin-Yuan Mo, William T. Beck & Susan P.C. Cole. (2007) Topoisomerase II binds importin α isoforms and exportin/CRM1 but does not shuttle between the nucleus and cytoplasm in proliferating cells. Experimental Cell Research 313:3, pages 627-637.
Crossref
Yoshiki Sasai. (2007) A Matter of Some Importins: Nuclear Transport Factors in ES Cell Maintenance and Differentiation. Developmental Cell 12:2, pages 172-174.
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Noriko Yasuhara, Noriko Shibazaki, Shinya Tanaka, Masahiro Nagai, Yasunao Kamikawa, Souichi Oe, Munehiro Asally, Yusuke Kamachi, Hisato Kondoh & Yoshihiro Yoneda. (2006) Triggering neural differentiation of ES cells by subtype switching of importin-α. Nature Cell Biology 9:1, pages 72-79.
Crossref
James R. Davis, Mudit Kakar & Carol S. Lim. (2006) Controlling Protein Compartmentalization to Overcome Disease. Pharmaceutical Research 24:1, pages 17-27.
Crossref
Jianhua Zhang, Hidefumi Ito, Reika Wate, Shizuo Ohnishi, Satoshi Nakano & Hirofumi Kusaka. (2006) Altered distributions of nucleocytoplasmic transport-related proteins in the spinal cord of a mouse model of amyotrophic lateral sclerosis. Acta Neuropathologica 112:6, pages 673-680.
Crossref
Kathryn E. Plant, David M. Everett, G. Gordon Gibson, Jon Lyon & Nick J. Plant. (2006) Transcriptomic and phylogenetic analysis of Kpna genes: a family of nuclear import factors modulated in xenobiotic-mediated liver growth. Pharmacogenetics and Genomics 16:9, pages 647-658.
Crossref
Nancy C. Reich & Ling Liu. (2006) Tracking STAT nuclear traffic. Nature Reviews Immunology 6:8, pages 602-612.
Crossref
Jing Ma & Xinmin Cao. (2006) Regulation of Stat3 nuclear import by importin α5 and importin α7 via two different functional sequence elements. Cellular Signalling 18:8, pages 1117-1126.
Crossref
Klara Olofsdotter Otis, Kimberly R Thompson & Kelsey C Martin. (2006) Importin-mediated nuclear transport in neurons. Current Opinion in Neurobiology 16:3, pages 329-335.
Crossref
Gen-Der Chen, Chih-Ming Chou, Sheng-Ping L. Hwang, Fung-Fang Wang, Yi-Chung Chen, Chin-Chun Hung, Jeou-Yuan Chen & Chang-Jen Huang. (2006) Requirement of nuclear localization and transcriptional activity of p53 for its targeting to the yolk syncytial layer (YSL) nuclei in zebrafish embryo and its use for apoptosis assay. Biochemical and Biophysical Research Communications 344:1, pages 272-282.
Crossref
Mayumi Nishi & Mitsuhiro Kawata. (2016) Brain Corticosteroid Receptor Dynamics and Trafficking: Implications from Live Cell Imaging. The Neuroscientist 12:2, pages 119-133.
Crossref
Mátyás Gorjánácz, István Török, István Pomozi, Győző Garab, Tamás Szlanka, István Kiss & Bernard M. Mechler. (2006) Domains of Importin-α2 required for ring canal assembly during Drosophila oogenesis. Journal of Structural Biology 154:1, pages 27-41.
Crossref
Marc Arnold, Annegret Nath, Daniel Wohlwend & Ralph H. Kehlenbach. (2006) Transportin Is a Major Nuclear Import Receptor for c-Fos. Journal of Biological Chemistry 281:9, pages 5492-5499.
Crossref
Marieke A. E. M. van der Aa, Enrico Mastrobattista, Ronald S. Oosting, Wim E. Hennink, Gerben A. Koning & Daan J. A. Crommelin. (2006) The Nuclear Pore Complex: The Gateway to Successful Nonviral Gene Delivery. Pharmaceutical Research 23:3, pages 447-459.
Crossref
Christina L. Stallings, Gregory J. Duigou, Anne A. Gershon, Michael D. Gershon & Saul J. Silverstein. (2006) The Cellular Localization Pattern of Varicella-Zoster Virus ORF29p Is Influenced by Proteasome-Mediated Degradation. Journal of Virology 80:3, pages 1497-1512.
Crossref
Sanjay Kumar, Mallampati Saradhi, Nagendra K. Chaturvedi & Rakesh K. Tyagi. (2006) Intracellular localization and nucleocytoplasmic trafficking of steroid receptors: An overview. Molecular and Cellular Endocrinology 246:1-2, pages 147-156.
Crossref
Satoko Aratani, Takayuki Oishi, Hidetoshi Fujita, Minako Nakazawa, Ryouji Fujii, Naoko Imamoto, Yoshihiro Yoneda, Akiyoshi Fukamizu & Toshihiro Nakajima. (2006) The nuclear import of RNA helicase A is mediated by importin-α3. Biochemical and Biophysical Research Communications 340:1, pages 125-133.
Crossref
Tanja Ilmarinen, Krister Melen, Hannele Kangas, Ilkka Julkunen, Ismo Ulmanen & Petra Eskelin. (2006) The monopartite nuclear localization signal of autoimmune regulator mediates its nuclear import and interaction with multiple importin alpha molecules. FEBS Journal 273:2, pages 315-324.
Crossref
Cathryn A. Hogarth, Sophina Calanni, David A. Jans & Kate L. Loveland. (2006) Importin α mRNAs have distinct expression profiles during spermatogenesis. Developmental Dynamics 235:1, pages 253-262.
Crossref
Christina L. Stallings & Saul Silverstein. (2005) Dissection of a Novel Nuclear Localization Signal in Open Reading Frame 29 of Varicella-Zoster Virus. Journal of Virology 79:20, pages 13070-13081.
Crossref
Cathryn Hogarth, Catherine Itman, David A. Jans & Kate L. Loveland. (2005) Regulated nucleocytoplasmic transport in spermatogenesis: a driver of cellular differentiation?. BioEssays 27:10, pages 1011-1025.
Crossref
Makoto Umeda, Shahed Izaddoost, Ian Cushman, Mary Shannon Moore & Shelley Sazer. (2005) The Fission Yeast Schizosaccharomyces pombe Has Two Importin-α Proteins, Imp1p and Cut15p, Which Have Common and Unique Functions in Nucleocytoplasmic Transport and Cell Cycle Progression . Genetics 171:1, pages 7-21.
Crossref
Ling Liu, Kevin M. McBride & Nancy C. Reich. (2005) STAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-α3. Proceedings of the National Academy of Sciences 102:23, pages 8150-8155.
Crossref
Kristoffer Palma, Yuelin Zhang & Xin Li. (2005) An Importin α Homolog, MOS6, Plays an Important Role in Plant Innate Immunity. Current Biology 15:12, pages 1129-1135.
Crossref
Marcos R.M. Fontes, Trazel Teh, Ryan D. Riell, Seung Bum Park, Robert F. Standaert & Bostjan Kobe. (2005) Crystallization and preliminary X-ray diffraction analysis of importin-α complexed with NLS peptidomimetics. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1750:1, pages 9-13.
Crossref
Ryosuke Ushijima, Naoko Sakaguchi, Arihiro Kano, Atsushi Maruyama, Yoichi Miyamoto, Toshihiro Sekimoto, Yoshihiro Yoneda, Kenji Ogino & Taro Tachibana. (2005) Extracellular signal-dependent nuclear import of STAT3 is mediated by various importin αs. Biochemical and Biophysical Research Communications 330:3, pages 880-886.
Crossref
Riku Fagerlund, Leena Kinnunen, Matthias Köhler, Ilkka Julkunen & Krister Melén. (2005) NF-κB Is Transported into the Nucleus by Importin α3 and Importin α4. Journal of Biological Chemistry 280:16, pages 15942-15951.
Crossref
Yoko Sakakida, Yoichi Miyamoto, Emi Nagoshi, Makoto Akashi, Takahiro J. Nakamura, Takayoshi Mamine, Megumi Kasahara, Yasuhiro Minami, Yoshihiro Yoneda & Toru Takumi. (2005) Importin α/β Mediates Nuclear Transport of a Mammalian Circadian Clock Component, mCRY2, Together with mPER2, through a Bipartite Nuclear Localization Signal. Journal of Biological Chemistry 280:14, pages 13272-13278.
Crossref
David Pasdeloup, Nicolas Poisson, Hélène Raux, Yves Gaudin, Rob W.H. Ruigrok & Danielle Blondel. (2005) Nucleocytoplasmic shuttling of the rabies virus P protein requires a nuclear localization signal and a CRM1-dependent nuclear export signal. Virology 334:2, pages 284-293.
Crossref
Richard J. Sessler & Noa Noy. (2005) A Ligand-Activated Nuclear Localization Signal in Cellular Retinoic Acid Binding Protein-II. Molecular Cell 18:3, pages 343-353.
Crossref
Ivan K. H. Poon & David A. Jans. (2005) Regulation of Nuclear Transport: Central Role in Development and Transformation?. Traffic 6:3, pages 173-186.
Crossref
Hualin Zhong, Akiko Takeda, Reza Nazari, Helen Shio, Günter Blobel & Nabeel R. Yaseen. (2005) Carrier-independent Nuclear Import of the Transcription Factor PU.1 via RanGTP-stimulated Binding to Nup153. Journal of Biological Chemistry 280:11, pages 10675-10682.
Crossref
Micah M. Bhatti & William J. SullivanJr.Jr.. (2005) Histone Acetylase GCN5 Enters the Nucleus via Importin-α in Protozoan Parasite Toxoplasma gondii. Journal of Biological Chemistry 280:7, pages 5902-5908.
Crossref
David A. Jans & Jade K. Forwood. 2005. Nuclear Import and Export in Plants and Animals. Nuclear Import and Export in Plants and Animals 137 160 .

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