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Cell Growth and Development

Cyclin D1 Is Required for Transformation by Activated Neu and Is Induced through an E2F-Dependent Signaling Pathway

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Pages 672-683 | Received 16 Jun 1999, Accepted 11 Oct 1999, Published online: 28 Mar 2023

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Crossref
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Crossref
Marcelo Cruz, Tomás Reinert & Massimo Cristofanilli. (2018) Emerging Innovative Therapeutic Approaches Leveraging Cyclin‐Dependent Kinase Inhibitors to Treat Advanced Breast Cancer. Clinical Pharmacology & Therapeutics 103:6, pages 1009-1019.
Crossref
Mark D. PegramYu ZongClinton YamMatthew P. GoetzStacy L. Moulder. (2018) Innovative Strategies: Targeting Subtypes in Metastatic Breast Cancer. American Society of Clinical Oncology Educational Book:38, pages 65-77.
Crossref
Nicholas LX Syn, Ian Wee, Andrea Li-Ann Wong, Robby M Goh, Samuel Guan-Wei Ow, Matteo Lambertini & Soo-Chin Lee. (2018) Cyclin-dependent kinase (CDK) inhibitors for hormone receptor-positive advanced breast cancer. Cochrane Database of Systematic Reviews.
Crossref
Claudio Valenzuela & Nelson E. Brown. 2018. D-type Cyclins and Cancer. D-type Cyclins and Cancer 111 131 .
Gabriele Di Sante, Mathew C. Casimiro, Zhiping Li, Adam Ertel, Peter Tompa & Richard G. Pestell. 2018. D-type Cyclins and Cancer. D-type Cyclins and Cancer 61 90 .
Luis Fernando Méndez-López, Jose Davila-Velderrain, Elisa Domínguez-Hüttinger, Christian Enríquez-Olguín, Juan Carlos Martínez-García & Elena R. Alvarez-Buylla. (2017) Gene regulatory network underlying the immortalization of epithelial cells. BMC Systems Biology 11:1.
Crossref
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Crossref
Shaymaa M.M. Yahya, Abdou O. Abdelhamid, Mervat M. Abd-Elhalim, Ghada H. Elsayed & Emad F. Eskander. (2017) The effect of newly synthesized progesterone derivatives on apoptotic and angiogenic pathway in MCF-7 breast cancer cells. Steroids 126, pages 15-23.
Crossref
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Farrukh Aqil, Jeyaprakash Jeyabalan, Radha Munagala, Srivani Ravoori, Manicka Vadhanam, David Schultz & Ramesh Gupta. (2017) Chemoprevention of Rat Mammary Carcinogenesis by Apiaceae Spices. International Journal of Molecular Sciences 18:2, pages 425.
Crossref
Nageswara Rao Reddy Neelapu. 2017. Role of Transcription Factors in Gastrointestinal Malignancies. Role of Transcription Factors in Gastrointestinal Malignancies 107 130 .
Mathew C. Casimiro, Richard G. Pestell & Erik S. Knudsen. 2017. Cancer Therapeutic Targets. Cancer Therapeutic Targets 989 996 .
Shuo Qie & J. Alan Diehl. (2016) Cyclin D1, cancer progression, and opportunities in cancer treatment. Journal of Molecular Medicine 94:12, pages 1313-1326.
Crossref
Xiaoming Ju, Xuanmao Jiao, Adam Ertel, Mathew C. Casimiro, Gabriele Di Sante, Shengqiong Deng, Zhiping Li, Agnese Di Rocco, Tingting Zhan, Adam Hawkins, Tanya Stoyanova, Sebastiano Andò, Alessandro Fatatis, Michael P. Lisanti, Leonard G. Gomella, Lucia R. Languino & Richard G. Pestell. (2016) v-Src Oncogene Induces Trop2 Proteolytic Activation via Cyclin D1. Cancer Research 76:22, pages 6723-6734.
Crossref
Gamal A. Elmegeed, Shaymaa M.M. Yahya, Mervat M. Abd-Elhalim, Mervat S. Mohamed, Rafat M. Mohareb & Ghada H. Elsayed. (2016) Evaluation of heterocyclic steroids and curcumin derivatives as anti-breast cancer agents: Studying the effect on apoptosis in MCF-7 breast cancer cells. Steroids 115, pages 80-89.
Crossref
Tamás Kovács, Gyula Batta, Tímea Hajdu, Ágnes Szabó, Tímea Váradi, Florina Zákány, István Csomós, János Szöllősi & Peter Nagy. (2016) The Dipole Potential Modifies the Clustering and Ligand Binding Affinity of ErbB Proteins and Their Signaling Efficiency. Scientific Reports 6:1.
Crossref
Ben O'Leary, Richard S. Finn & Nicholas C. Turner. (2016) Treating cancer with selective CDK4/6 inhibitors. Nature Reviews Clinical Oncology 13:7, pages 417-430.
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Mathew C. Casimiro, Gabriele Di Sante, Xiaoming Ju, Zhiping Li, Ke Chen, Marco Crosariol, Ismail Yaman, Michael Gormley, Hui Meng, Michael P. Lisanti & Richard G. Pestell. (2016) Cyclin D1 Promotes Androgen-Dependent DNA Damage Repair in Prostate Cancer Cells. Cancer Research 76:2, pages 329-338.
Crossref
Mathew C. Casimiro, Richard G. Pestell & Erik S. Knudsen. 2016. Cancer Therapeutic Targets. Cancer Therapeutic Targets 1 8 .
R I Cordo Russo, W Béguelin, M C Díaz Flaqué, C J Proietti, L Venturutti, N Galigniana, M Tkach, P Guzmán, J C Roa, N A O'Brien, E H Charreau, R Schillaci & P V Elizalde. (2014) Targeting ErbB-2 nuclear localization and function inhibits breast cancer growth and overcomes trastuzumab resistance. Oncogene 34:26, pages 3413-3428.
Crossref
Mathew C. Casimiro, Gabriele Di Sante, Marco Crosariol, Emanuele Loro, William Dampier, Adam Ertel, Zuoren Yu, Elizabeth A. Saria, Alexandros Papanikolaou, Zhiping Li, Chenguang Wang, Sankar Addya, Michael P. Lisanti, Paolo Fortina, Robert D. Cardiff, Aydin Tozeren, Erik S. Knudsen, Andrew Arnold & Richard G. Pestell. (2015) Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis. Oncotarget 6:11, pages 8525-8538.
Crossref
Maria Schwaederlé, Gregory A. Daniels, David E. Piccioni, Paul T. Fanta, Richard B. Schwab, Kelly A. Shimabukuro, Barbara A. Parker & Razelle Kurzrock. (2014) Cyclin alterations in diverse cancers: outcome and co-amplification network. Oncotarget 6:5, pages 3033-3042.
Crossref
E R Andrechek. (2013) HER2/Neu tumorigenesis and metastasis is regulated by E2F activator transcription factors. Oncogene 34:2, pages 217-225.
Crossref
Heather L. LehmanDouglas B. Stairs. (2015) Single and Multiple Gene Manipulations in Mouse Models of Human Cancer. Cancer Growth and Metastasis 8s1, pages CGM.S21217.
Crossref
Mathew C. Casimiro, Richard G. Pestell & Erik S. Knudsen. 2015. Cancer Therapeutic Targets. Cancer Therapeutic Targets 1 8 .
Xiaopeng Zhang. (2014) Depression of testes-specific protease 50 (TSP50) inhibits cell proliferation and induces apoptosis in laryngocarcinoma. Tumor Biology 35:11, pages 10781-10788.
Crossref
Zhiping Li, Ke Chen, Xuanmao Jiao, Chenguang Wang, Nicole E. Willmarth, Mathew C. Casimiro, Weihua Li, Xiaoming Ju, Sung Hoon Kim, Michael P. Lisanti, John A. Katzenellenbogen & Richard G. Pestell. (2014) Cyclin D1 Integrates Estrogen-Mediated DNA Damage Repair Signaling. Cancer Research 74:14, pages 3959-3970.
Crossref
HongBin Wang, Alvaro Gutierrez-Uzquiza, Rachana Garg, Laura Barrio-Real, Mahlet B. Abera, Cynthia Lopez-Haber, Cinthia Rosemblit, Huaisheng Lu, Martin Abba & Marcelo G. Kazanietz. (2014) Transcriptional Regulation of Oncogenic Protein Kinase Cϵ (PKCϵ) by STAT1 and Sp1 Proteins. Journal of Biological Chemistry 289:28, pages 19823-19838.
Crossref
Zuoren Yu, Zengguang Xu, Gabriele DiSante, Jennifer Wright, Min Wang, Yuan Li, Qian Zhao, Tao Ren, Xiaoming Ju, Ellen Gutman, Guangxue Wang, Sankar Addya, Tieyan Li, Zhendong Xiang, Chenguang Wang, Xiongfei yang, Xiaolai Yang & Richard Pestell. (2014) miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1 . Oncotarget 5:4, pages 1083-1090.
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Ditte Brix, Knut Clemmensen & Tuula Kallunki. (2014) When Good Turns Bad: Regulation of Invasion and Metastasis by ErbB2 Receptor Tyrosine Kinase. Cells 3:1, pages 53-78.
Crossref
Chenguang Wang, Xuemin Zhang, Lifeng Tian & Richard G. Pestell. 2015. Molecular Oncology. Molecular Oncology 392 402 .
Sinan Zhu, Ryan T. Mott, Elizabeth A. Fry, Pankaj Taneja, George Kulik, Guangchao Sui & Kazushi Inoue. (2013) Cooperation between Dmp1 Loss and Cyclin D1 Overexpression in Breast Cancer. The American Journal of Pathology 183:4, pages 1339-1350.
Crossref
Travis B. Salisbury, Gary Z. Morris, Justin K. Tomblin, Ateeq R. Chaudhry, Carla R. Cook & Nalini Santanam. (2013) Aryl Hydrocarbon Receptor Ligands Inhibit IGF-II and Adipokine Stimulated Breast Cancer Cell Proliferation. ISRN Endocrinology 2013, pages 1-9.
Crossref
Kongming Wu, Zhaoming Li, Shaoxin Cai, Lifeng Tian, Ke Chen, Jing Wang, Junbo Hu, Ye Sun, Xue Li, Adam Ertel & Richard G. Pestell. (2013) EYA1 Phosphatase Function Is Essential to Drive Breast Cancer Cell Proliferation through Cyclin D1. Cancer Research 73:14, pages 4488-4499.
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Meiou Dai, Amal A Al-Odaini, Nadège Fils-Aimé, Manuel A Villatoro, Jimin Guo, Ani Arakelian, Shafaat A Rabbani, Suhad Ali & Jean Jacques Lebrun. (2013) Cyclin D1 cooperates with p21 to regulate TGFβ-mediated breast cancer cell migration and tumor local invasion. Breast Cancer Research 15:3.
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Mary Kathryn Harrison Pitner & Harold I. Saavedra. (2013) Cdk4 and Nek2 Signal Binucleation and Centrosome Amplification in a Her2+ Breast Cancer Model. PLoS ONE 8:6, pages e65971.
Crossref
Lin Yue, Leilei Li, Fangfang Liu, Nan Hu, Weiying Zhang, Xiao Bai, Yinghui Li, Yingyi Zhang, Li Fu, Xiaodong Zhang & Lihong Ye. (2013) The oncoprotein HBXIP activates transcriptional coregulatory protein LMO4 via Sp1 to promote proliferation of breast cancer cells. Carcinogenesis 34:4, pages 927-935.
Crossref
Da Mi, Catherine B. Carr, Petrina A. Georgala, Yu-Ting Huang, Martine N. Manuel, Emily Jeanes, Emi Niisato, Stephen N. Sansom, Frederick J. Livesey, Thomas Theil, Kerstin Hasenpusch-Theil, T. Ian Simpson, John O. Mason & David J. Price. (2013) Pax6 Exerts Regional Control of Cortical Progenitor Proliferation via Direct Repression of Cdk6 and Hypophosphorylation of pRb. Neuron 78:2, pages 269-284.
Crossref
Zuoren Yu, Aydin Tozeren & Richard G. Pestell. 2013. MicroRNA in Cancer. MicroRNA in Cancer 13 27 .
Chenguang Wang, Timothy G. Pestell & Richard G. Pestell. 2013. Cell and Molecular Biology of Breast Cancer. Cell and Molecular Biology of Breast Cancer 289 304 .
Xinfeng Yu, Xuemei Zhang, Ishwori B Dhakal, Marjorie Beggs, Susan Kadlubar & Dali Luo. (2012) Induction of cell proliferation and survival genes by estradiol-repressed microRNAs in breast cancer cells. BMC Cancer 12:1.
Crossref
Anthony Mazurek, Weijun Luo, Alexander Krasnitz, James Hicks, R. Scott Powers & Bruce Stillman. (2012) DDX5 Regulates DNA Replication and Is Required for Cell Proliferation in a Subset of Breast Cancer Cells. Cancer Discovery 2:9, pages 812-825.
Crossref
Jinghua Han, Fei Zhang, Man Yu, Peiqi Zhao, Wei Ji, Haichang Zhang, Bing Wu, Yuqing Wang & Ruifang Niu. (2012) RNA interference-mediated silencing of NANOG reduces cell proliferation and induces G0/G1 cell cycle arrest in breast cancer cells. Cancer Letters 321:1, pages 80-88.
Crossref
Zuoren Yu & Richard G. Pestell. (2012) Small Non-coding RNAs Govern Mammary Gland Tumorigenesis. Journal of Mammary Gland Biology and Neoplasia 17:1, pages 59-64.
Crossref
Aldema Sas-Chen, Roi Avraham & Yosef Yarden. (2012) A Crossroad of microRNAs and Immediate Early Genes (IEGs) Encoding Oncogenic Transcription Factors in Breast Cancer. Journal of Mammary Gland Biology and Neoplasia 17:1, pages 3-14.
Crossref
William P. Clafshenkel, Tracy L. King, Mary P. Kotlarczyk, J. Mark Cline, Warren G. Foster, Vicki L. Davis & Paula A. Witt-Enderby. (2012) Morinda citrifolia (Noni) Juice Augments Mammary Gland Differentiation and Reduces Mammary Tumor Growth in Mice Expressing the Unactivated c- erb B2 Transgene . Evidence-Based Complementary and Alternative Medicine 2012, pages 1-15.
Crossref
Neill Patani, Lesley-Ann Martin, Jorge S. Reis-Filho & Mitch Dowsett. (2011) The role of caveolin-1 in human breast cancer. Breast Cancer Research and Treatment 131:1, pages 1-15.
Crossref
Gloria Bonuccelli & Michael P. Lisanti. 2012. Caveolins in Cancer Pathogenesis, Prevention and Therapy. Caveolins in Cancer Pathogenesis, Prevention and Therapy 91 104 .
Mary K Harrison, Arsene M Adon & Harold I Saavedra. (2011) The G1 phase Cdks regulate the centrosome cycle and mediate oncogene-dependent centrosome amplification. Cell Division 6:1.
Crossref
Shinji Mizuarai, Takumitsu Machida, Tsutomu Kobayashi, Hideya Komatani, Hiraku Itadani & Hidehito Kotani. (2011) Expression ratio of CCND1 to CDKN2A mRNA predicts RB1 status of cultured cancer cell lines and clinical tumor samples. Molecular Cancer 10:1.
Crossref
Doyel Mitra, Partha M. Das, Felicia C. Huynh & Frank E. Jones. (2011) Jumonji/ARID1 B (JARID1B) Protein Promotes Breast Tumor Cell Cycle Progression through Epigenetic Repression of MicroRNA let-7e. Journal of Biological Chemistry 286:47, pages 40531-40535.
Crossref
Elizabeth A. Musgrove, C. Elizabeth Caldon, Jane Barraclough, Andrew Stone & Robert L. Sutherland. (2011) Cyclin D as a therapeutic target in cancer. Nature Reviews Cancer 11:8, pages 558-572.
Crossref
Zhi-yi Guo, Xiao-hui Hao, Fei-Fei Tan, Xin Pei, Li-Mei Shang, Xue-lian Jiang & Fang Yang. (2011) The elements of human cyclin D1 promoter and regulation involved. Clinical Epigenetics 2:2, pages 63-76.
Crossref
Marco A Velasco-Velázquez, Zhiping Li, Mathew Casimiro, Emanuele Loro, Nora Homsi & Richard G Pestell. (2011) Examining the role of cyclin D1 in breast cancer. Future Oncology 7:6, pages 753-765.
Crossref
Zhen-Bo Song, Yong-Li Bao, Yu Zhang, Xu-Guang Mi, Ping Wu, Yin Wu, Chun-Lei Yu, Ying Sun, Li-Hua Zheng, Yan-Xin Huang, Biao Liu & Yu-Xin Li. (2011) Testes-specific protease 50 (TSP50) promotes cell proliferation through the activation of the nuclear factor κB (NF-κB) signalling pathway. Biochemical Journal 436:2, pages 457-467.
Crossref
Xi Wang, Shuang Feng, Hong Zhang, Yang Wang, Yuying Cui, Zhaoyi Wang, Jing Liu & Wei Zou. (2010) RNA inference-mediated caveolin-1 down-regulation decrease estrogen receptor alpha (ERα) signaling in human mammary epithelial cells. Molecular Biology Reports 38:2, pages 761-768.
Crossref
Manran Liu, Toshiyuki Sakamaki, Mathew C. Casimiro, Nicole E. Willmarth, Andrew A. Quong, Xiaoming Ju, John Ojeifo, Xuanmao Jiao, Wen-Shuz Yeow, Sanjay Katiyar, L. Andrew Shirley, David Joyce, Michael P. Lisanti, Christopher Albanese & Richard G. Pestell. (2010) The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion. Cancer Research 70:24, pages 10464-10473.
Crossref
Maria Soledad Sosa, Cynthia Lopez-Haber, Chengfeng Yang, HongBin Wang, Mark A. Lemmon, John M. Busillo, Jiansong Luo, Jeffrey L. Benovic, Andres Klein-Szanto, Hiroshi Yagi, J. Silvio Gutkind, Ramon E. Parsons & Marcelo G. Kazanietz. (2010) Identification of the Rac-GEF P-Rex1 as an Essential Mediator of ErbB Signaling in Breast Cancer. Molecular Cell 40:6, pages 877-892.
Crossref
Dhan V. Kalvakolanu, Shreeram C. Nallar & Sudhakar Kalakonda. (2010) Cytokine-induced tumor suppressors: A GRIM story. Cytokine 52:1-2, pages 128-142.
Crossref
M. Lanzino, D. Sisci, C. Morelli, C. Garofalo, S. Catalano, I. Casaburi, C. Capparelli, C. Giordano, F. Giordano, M. Maggiolini & S. Ando. (2010) Inhibition of cyclin D1 expression by androgen receptor in breast cancer cells--identification of a novel androgen response element. Nucleic Acids Research 38:16, pages 5351-5365.
Crossref
W-L Yang, X Zhang & H-K Lin. (2010) Emerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer development. Oncogene 29:32, pages 4493-4503.
Crossref
E A Mittendorf, Y Liu, S L Tucker, T McKenzie, N Qiao, S Akli, A Biernacka, Y Liu, L Meijer, K Keyomarsi & K K Hunt. (2010) A novel interaction between HER2/neu and cyclin E in breast cancer. Oncogene 29:27, pages 3896-3907.
Crossref
Fabrício F T Barros, Desmond G Powe, Ian O Ellis & Andrew R Green. (2010) Understanding the HER family in breast cancer: interaction with ligands, dimerization and treatments. Histopathology 56:5, pages 560-572.
Crossref
Zuoren Yu, Renato Baserga, Lide Chen, Chenguang Wang, Michael P. Lisanti & Richard G. Pestell. (2010) microRNA, Cell Cycle, and Human Breast Cancer. The American Journal of Pathology 176:3, pages 1058-1064.
Crossref
Wen Wen, Jin Ding, Wen Sun, Kun Wu, Beifang Ning, Wenfeng Gong, Guoping He, Shanna Huang, Xinyu Ding, Peipei Yin, Lei Chen, Qiong Liu, Weifen Xie & Hongyang Wang. (2010) Suppression of Cyclin D1 by Hypoxia-Inducible Factor-1 via Direct Mechanism Inhibits the Proliferation and 5-Fluorouracil–Induced Apoptosis of A549 Cells. Cancer Research 70:5, pages 2010-2019.
Crossref
Xiao Wang, Lan Chao, Xin Li, Guohui Ma, Liansheng Chen, Yixiu Zang & Gengyin Zhou. (2010) Elevated expression of phosphorylated c-Jun NH2-terminal kinase in basal-like and “triple-negative” breast cancers. Human Pathology 41:3, pages 401-406.
Crossref
Jun-Yuan Ji & Nicholas J. Dyson. 2010. Cell Cycle Deregulation in Cancer. Cell Cycle Deregulation in Cancer 23 41 .
Elise L. Ma, Yoon Jeong Choi, Jinyoung Choi, Charalabos Pothoulakis, Sang Hoon Rhee & Eunok Im. (2010) The anticancer effect of probiotic Bacillus polyfermenticus on human colon cancer cells is mediated through ErbB2 and ErbB3 inhibition . International Journal of Cancer, pages NA-NA.
Crossref
Sharon J Sequeira, Huei Chi Wen, Alvaro Avivar-Valderas, Eduardo F Farias & Julio A Aguirre-Ghiso. (2009) Inhibition of eIF2α dephosphorylation inhibits ErbB2-induced deregulation of mammary acinar morphogenesis. BMC Cell Biology 10:1.
Crossref
Zhiyi Guo, Jinshan Wang, Jun Yang, Ning-hua Wu, Ye Zhang & Yu-fei Shen. (2009) An inhibitory role of p53 via NF-κB element on the cyclin D1 gene under heat shock. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1789:11-12, pages 758-762.
Crossref
M E Montañez-Wiscovich, D D Seachrist, M D Landis, J Visvader, B Andersen & R A Keri. (2009) LMO4 is an essential mediator of ErbB2/HER2/Neu-induced breast cancer cell cycle progression. Oncogene 28:41, pages 3608-3618.
Crossref
Vladimir M. Popov, Jie Zhou, L. Andrew Shirley, Judy Quong, Wen-Shuz Yeow, Jennifer A. Wright, Kongming Wu, Hallgeir Rui, Ratna K. Vadlamudi, Jie Jiang, Rakesh Kumar, Chenguang Wang & Richard G. Pestell. (2009) The Cell Fate Determination Factor DACH1 Is Expressed in Estrogen Receptor-α–Positive Breast Cancer and Represses Estrogen Receptor-α Signaling. Cancer Research 69:14, pages 5752-5760.
Crossref
Vikram B. Wali, Sunitha V. Bachawal & Paul W. Sylvester. (2009) Combined Treatment of γ-Tocotrienol with Statins Induce Mammary Tumor Cell Cycle Arrest in G1. Experimental Biology and Medicine 234:6, pages 639-650.
Crossref
Hu HuangYi-de HuNa LiYong Zhu. (2009) Inhibition of Tumor Growth and Metastasis by Non–Small Cell Lung Cancer Cells Transfected With Cyclin D1–Targeted siRNA. Oligonucleotides 19:2, pages 151-161.
Crossref
Paola Rojas, Fernando Benavides, Jorge Blando, Carlos Perez, Kim Cardenas, Ellen Richie, Erik S. Knudsen, David G. Johnson, Adrian M. Senderowicz, Marcelo L. Rodriguez-Puebla & Claudio J. Conti. (2009) Enhanced skin carcinogenesis and lack of thymus hyperplasia in transgenic mice expressing human cyclin D1b ( CCND1b ) . Molecular Carcinogenesis 48:6, pages 508-516.
Crossref
Manran Liu, Xiaoming Ju, Nicole E. Willmarth, Mathew C. Casimiro, John Ojeifo, Toshiyuki Sakamaki, Sanjay Katiyar, Xuanmao Jiao, Vladimir M. Popov, Zuoren Yu, Kongming Wu, David Joyce, Chenguang Wang & Richard G. Pestell. (2009) Nuclear Factor-κB Enhances ErbB2-Induced Mammary Tumorigenesis and Neoangiogenesis in Vivo. The American Journal of Pathology 174:5, pages 1910-1920.
Crossref
Francesco Marampon, Gianluca Bossi, Carmela Ciccarelli, Agnese Di Rocco, Ada Sacchi, Richard G. Pestell & Bianca M. Zani. (2009) MEK/ERK inhibitor U0126 affects in vitro and in vivo growth of embryonal rhabdomyosarcoma . Molecular Cancer Therapeutics 8:3, pages 543-551.
Crossref
Rosanna Sestito & Paola Palozza. 2009. Lycopene. Lycopene 133 158 .
Zuoren Yu, Chenguang Wang, Min Wang, Zhiping Li, Mathew C. Casimiro, Manran Liu, Kongming Wu, James Whittle, Xiaoming Ju, Terry Hyslop, Peter McCue & Richard G. Pestell. (2008) A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. Journal of Cell Biology 182:3, pages 509-517.
Crossref
Ian N. Fleming, Morag Hogben, Sheelagh Frame, Steven J. McClue & Simon R. Green. (2008) Synergistic Inhibition of ErbB Signaling by Combined Treatment with Seliciclib and ErbB-Targeting Agents. Clinical Cancer Research 14:13, pages 4326-4335.
Crossref
Naomi Y. Jiang, Bruce A. Woda, Barbara F. Banner, Giles F. Whalen, Karen A. Dresser & Di Lu. (2008) Sp1, a New Biomarker That Identifies a Subset of Aggressive Pancreatic Ductal Adenocarcinoma. Cancer Epidemiology, Biomarkers & Prevention 17:7, pages 1648-1652.
Crossref
Irina Neganova & Majlinda Lako. (2008) G1 to S phase cell cycle transition in somatic and embryonic stem cells. Journal of Anatomy 213:1, pages 30-44.
Crossref
Mark P. Fereshteh, Maddalena T. Tilli, Sung Eun Kim, Jianming Xu, Bert W. O'Malley, Anton Wellstein, Priscilla A. Furth & Anna T. Riegel. (2008) The Nuclear Receptor Coactivator Amplified in Breast Cancer-1 Is Required for Neu (ErbB2/HER2) Activation, Signaling, and Mammary Tumorigenesis in Mice . Cancer Research 68:10, pages 3697-3706.
Crossref
Kongming Wu, Sanjay Katiyar, Anping Li, Manran Liu, Xiaoming Ju, Vladimir M. Popov, Xuanmao Jiao, Michael P. Lisanti, Antonella Casola & Richard G. Pestell. (2008) Dachshund inhibits oncogene-induced breast cancer cellular migration and invasion through suppression of interleukin-8. Proceedings of the National Academy of Sciences 105:19, pages 6924-6929.
Crossref
Robert A. Jones, Craig I. Campbell, James J. Petrik & Roger A. Moorehead. (2008) Characterization of a Novel Primary Mammary Tumor Cell Line Reveals that Cyclin D1 Is Regulated by the Type I Insulin-Like Growth Factor Receptor. Molecular Cancer Research 6:5, pages 819-828.
Crossref
Ye LUO, Yu HAO, Tai-ping SHI, Wei-wei DENG & Na LI. (2008) Berberine inhibits cyclin D1 expression via suppressed binding of AP-1 transcription factors to CCND1 AP-1 motif. Acta Pharmacologica Sinica 29:5, pages 628-633.
Crossref
Jennifer F. Raven, Dionissios Baltzis, Shuo Wang, Zineb Mounir, Andreas I. Papadakis, Hong Qing Gao & Antonis E. Koromilas. (2008) PKR and PKR-like Endoplasmic Reticulum Kinase Induce the Proteasome-dependent Degradation of Cyclin D1 via a Mechanism Requiring Eukaryotic Initiation Factor 2α Phosphorylation. Journal of Biological Chemistry 283:6, pages 3097-3108.
Crossref
Chad D. Knights & Richard G. Pestell. 2008. Molecular Targeting in Oncology. Molecular Targeting in Oncology 3 32 .
Valerie Stone Hawthorne & Dihua Yu. 2008. Regulation of Gene Expression in the Tumor Environment. Regulation of Gene Expression in the Tumor Environment 43 56 .
Alison J. Butt, C. Elizabeth Caldon, Catriona M. McNeil, Alexander Swarbrick, Elizabeth A. Musgrove & Robert L. Sutherland. 2008. Innovative Endocrinology of Cancer. Innovative Endocrinology of Cancer 189 205 .
M M Moasser. (2007) The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis. Oncogene 26:45, pages 6469-6487.
Crossref
Romaine Fernando, James S. Foster, Amber Bible, Anders Ström, Richard G. Pestell, Mahadev Rao, Arnold Saxton, Seung Joon Baek, Kiyoshi Yamaguchi, Robert Donnell, Maria Cekanova & Jay Wimalasena. (2007) Breast Cancer Cell Proliferation Is Inhibited by BAD. Journal of Biological Chemistry 282:39, pages 28864-28873.
Crossref
Kamini Singh, Devraj Mogare, Ramprasad Obula Giridharagopalan, Rajinikanth Gogiraju, Gopal Pande & Samit Chattopadhyay. (2007) p53 Target Gene SMAR1 Is Dysregulated in Breast Cancer: Its Role in Cancer Cell Migration and Invasion. PLoS ONE 2:8, pages e660.
Crossref
Kazuhito Sakamoto, Bradley A. Creamer, Aleata A. Triplett & Kay-Uwe Wagner. (2007) The Janus Kinase 2 Is Required for Expression and Nuclear Accumulation of Cyclin D1 in Proliferating Mammary Epithelial Cells. Molecular Endocrinology 21:8, pages 1877-1892.
Crossref
C Berthet & P Kaldis. (2007) Cell-specific responses to loss of cyclin-dependent kinases. Oncogene 26:31, pages 4469-4477.
Crossref
Shishir Shishodia, Madan M. Chaturvedi & Bharat B. Aggarwal. (2007) Role of Curcumin in Cancer Therapy. Current Problems in Cancer 31:4, pages 243-305.
Crossref
Mathew Casimiro, Olga Rodriguez, Llana Pootrakul, Maral Aventian, Nadia Lushina, Caroline Cromelin, Georgina Ferzli, Kevin Johnson, Stanley Fricke, Fantahun Diba, Bhaskar Kallakury, Chioma Ohanyerenwa, Maxine Chen, Michael Ostrowski, Mien-Chie Hung, Shafaat A. Rabbani, Ram Datar, Richard Cote, Richard Pestell & Chris Albanese. (2007) ErbB-2 Induces the Cyclin D1 Gene in Prostate Epithelial Cells In vitro and In vivo . Cancer Research 67:9, pages 4364-4372.
Crossref
Xiaoming Ju, Sanjay Katiyar, Chenguang WangManran Liu, Xuanmao Jiao, Shengwen Li, Jie Zhou, Jacob Turner, Michael P. Lisanti, Robert G. Russell, Susette C. Mueller, John Ojeifo, William S. Chen, Nissim Hay & Richard G. Pestell. (2007) Akt1 governs breast cancer progression in vivo . Proceedings of the National Academy of Sciences 104:18, pages 7438-7443.
Crossref
Patrick Corsino, Bradley Davis, Mary Law, Anna Chytil, Elizabeth Forrester, Peter Nørgaard, Nicole Teoh & Brian Law. (2007) Tumors Initiated by Constitutive Cdk2 Activation Exhibit Transforming Growth Factor β Resistance and Acquire Paracrine Mitogenic Stimulation during Progression. Cancer Research 67:7, pages 3135-3144.
Crossref
Andrea Kröger, Anja Stirnweiss, Julia Elisabeth Pulverer, Katjana Klages, Martina Grashoff, Jörg Reimann & Hansjörg Hauser. (2007) Tumor Suppression by IFN Regulatory Factor-1 Is Mediated by Transcriptional Down-regulation of Cyclin D1. Cancer Research 67:7, pages 2972-2981.
Crossref
Kongming WuManran LiuAnping LiHoward DonningerMahadev Rao, Xuanmao JiaoMichael P. LisantiAles Cvekl, Michael BirrerRichard G. Pestell. (2007) Cell Fate Determination Factor DACH1 Inhibits c-Jun–induced Contact-independent Growth. Molecular Biology of the Cell 18:3, pages 755-767.
Crossref
Sofi G Julien, Nadia Dubé, Michelle Read, Janice Penney, Marilene Paquet, Yongxin Han, Brian P Kennedy, William J Muller & Michel L Tremblay. (2007) Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis. Nature Genetics 39:3, pages 338-346.
Crossref
Chuanwei Yang, Sally Trent, Viviana Ionescu-Tiba, Lan Lan, Toshi Shioda, Dennis Sgroi & Emmett V. Schmidt. (2006) Identification of Cyclin D1– and Estrogen-Regulated Genes Contributing to Breast Carcinogenesis and Progression. Cancer Research 66:24, pages 11649-11658.
Crossref
Paola Mussi, Chundong Yu, Bert W. O’Malley & Jianming Xu. (2006) Stimulation of Steroid Receptor Coactivator-3 (SRC-3) Gene Overexpression by a Positive Regulatory Loop of E2F1 and SRC-3. Molecular Endocrinology 20:12, pages 3105-3119.
Crossref
Federica Sotgia, Hallgeir Rui, Gloria Bonuccelli, Isabelle Mercier, Richard G. Pestell & Michael P. Lisanti. (2006) Caveolin-1, Mammary Stem Cells, and Estrogen-Dependent Breast Cancers. Cancer Research 66:22, pages 10647-10651.
Crossref
Terence M. Williams, Federica Sotgia, Hyangkyu Lee, Ghada Hassan, Dolores Di Vizio, Gloria Bonuccelli, Franco Capozza, Isabelle Mercier, Hallgeir Rui, Richard G. Pestell & Michael P. Lisanti. (2006) Stromal and Epithelial Caveolin-1 Both Confer a Protective Effect Against Mammary Hyperplasia and Tumorigenesis. The American Journal of Pathology 169:5, pages 1784-1801.
Crossref
Kang Liu, Jason C Paik, Bing Wang, Fang-Tsyr Lin & Weei-Chin Lin. (2006) Regulation of TopBP1 oligomerization by Akt/PKB for cell survival. The EMBO Journal 25:20, pages 4795-4807.
Crossref
Aurora Aiello, Giuseppe Pandini, Francesco Frasca, Enrico Conte, Antonella Murabito, Antonella Sacco, Marco Genua, Riccardo Vigneri & Antonino Belfiore. (2006) Peroxisomal Proliferator-Activated Receptor-γ Agonists Induce Partial Reversion of Epithelial-Mesenchymal Transition in Anaplastic Thyroid Cancer Cells. Endocrinology 147:9, pages 4463-4475.
Crossref
James Hulit, Richard J. Lee, Zhiping Li, Chenguang Wang, Sanjay Katiyar, Jianguo Yang, Andrew A. Quong, Kongming Wu, Chris Albanese, Robert Russell, Dolores Di Vizio, Andrew Koff, Saiinder Thummala, Hui Zhang, Jennifer Harrell, Hong Sun, William J. Muller, Giorgio Inghirami, Michael P. Lisanti & Richard G. Pestell. (2006) p27Kip1 Repression of ErbB2-Induced Mammary Tumor Growth in Transgenic Mice Involves Skp2 and Wnt/β-Catenin Signaling . Cancer Research 66:17, pages 8529-8541.
Crossref
Anja Jaeschke, Maria Karasarides, Juan-Jose Ventura, Anka Ehrhardt, Chao Zhang, Richard A. Flavell, Kevan M. Shokat & Roger J. Davis. (2006) JNK2 Is a Positive Regulator of the cJun Transcription Factor. Molecular Cell 23:6, pages 899-911.
Crossref
Mark Stahl, Changhui Ge, Shaolin Shi, Richard G. Pestell & Pamela Stanley. (2006) Notch1-Induced Transformation of RKE-1 Cells Requires Up-regulation of Cyclin D1. Cancer Research 66:15, pages 7562-7570.
Crossref
Yao-Tsung Yeh, Ming-Feng Hou, Yueh-Fang Chung, Yi-Jiun Chen, Sheau-Fang Yang, Da-Chung Chen, Jinu-Huang Su & Shyng-Shiou F. Yuan. (2006) Decreased expression of phosphorylated JNK in breast infiltrating ductal carcinoma is associated with a better overall survival. International Journal of Cancer 118:11, pages 2678-2684.
Crossref
Weiming Ouyang, Jingxia Li, Qian Ma & Chuanshu Huang. (2006) Essential roles of PI-3K/Akt/IKKβ/NFκB pathway in cyclin D1 induction by arsenite in JB6 Cl41 cells. Carcinogenesis 27:4, pages 864-873.
Crossref
Marina Konopleva, Weiguo Zhang, Yue-Xi Shi, Teresa McQueen, Twee Tsao, Maen Abdelrahim, Mark F. Munsell, Mary Johansen, Dihua Yu, Timothy Madden, Stephen H. Safe, Mien-Chie Hung & Michael Andreeff. (2006) Synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest in HER2-overexpressing breast cancer cells. Molecular Cancer Therapeutics 5:2, pages 317-328.
Crossref
Mark W. Landis, Basil S. Pawlyk, Tiansen Li, Piotr Sicinski & Philip W. Hinds. (2006) Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis. Cancer Cell 9:1, pages 13-22.
Crossref
Qunyan Yu, Ewa Sicinska, Yan Geng, Marie Ahnström, Agnieszka Zagozdzon, Yinxin Kong, Humphrey Gardner, Hiroaki Kiyokawa, Lyndsay N. Harris, Olle Stål & Piotr Sicinski. (2006) Requirement for CDK4 kinase function in breast cancer. Cancer Cell 9:1, pages 23-32.
Crossref
Stacey M. Ivanchuk & James T. Rutka. 2006. Handbook of Brain Tumor Chemotherapy. Handbook of Brain Tumor Chemotherapy 123 140 .
Mary Grillo, Matthew J. Bott, Neha Khandke, John P. McGinnis, Miriam Miranda, Muthupalaniappan Meyyappan, Edward C. Rosfjord & Sridhar K. Rabindran. (2005) Validation of cyclin D1/CDK4 as an anticancer drug target in MCF-7 breast cancer cells: Effect of regulated overexpression of cyclin D1 and siRNA-mediated inhibition of endogenous cyclin D1 and CDK4 expression. Breast Cancer Research and Treatment 95:2, pages 185-194.
Crossref
Qunyan Yu, Maria A Ciemerych & Piotr Sicinski. (2005) Ras and Myc can drive oncogenic cell proliferation through individual D-cyclins. Oncogene 24:47, pages 7114-7119.
Crossref
Weiming Ouyang, Qian Ma, Jingxia Li, Dongyun Zhang, Zheng-gang Liu, Anil K. Rustgi & Chuanshu Huang. (2005) Cyclin D1 Induction through IκB Kinase β/Nuclear Factor-κB Pathway Is Responsible for Arsenite-Induced Increased Cell Cycle G1-S Phase Transition in Human Keratinocytes. Cancer Research 65:20, pages 9287-9293.
Crossref
Melissa D Landis, Darcie D Seachrist, Marjorie E Montañez-Wiscovich, David Danielpour & Ruth A Keri. (2005) Gene expression profiling of cancer progression reveals intrinsic regulation of transforming growth factor-β signaling in ErbB2/Neu-induced tumors from transgenic mice. Oncogene 24:33, pages 5173-5190.
Crossref
Chenguang Wang, Saijun Fan, Zhiping Li, Maofu Fu, Mahadev Rao, Yongxian Ma, Michael P. Lisanti, Chris Albanese, Benita S. Katzenellenbogen, Peter J. Kushner, Barbara Weber, Eliot M. Rosen & Richard G. Pestell. (2005) Cyclin D1 Antagonizes BRCA1 Repression of Estrogen Receptor α Activity. Cancer Research 65:15, pages 6557-6567.
Crossref
Takeshi Shimamura, April M. Lowell, Jeffrey A. Engelman & Geoffrey I. Shapiro. (2005) Epidermal Growth Factor Receptors Harboring Kinase Domain Mutations Associate with the Heat Shock Protein 90 Chaperone and Are Destabilized following Exposure to Geldanamycins. Cancer Research 65:14, pages 6401-6408.
Crossref
Peter M. BurchNicholas H. Heintz. (2005) Redox Regulation of Cell-Cycle Re-entry: Cyclin D1 as a Primary Target for the Mitogenic Effects of Reactive Oxygen and Nitrogen Species. Antioxidants & Redox Signaling 7:5-6, pages 741-751.
Crossref
Garabet Yeretssian, Michèle Lecocq, Guillaume Lebon, Helen C. Hurst & Vehary Sakanyan. (2005) Competition on Nitrocellulose-immobilized Antibody Arrays. Molecular & Cellular Proteomics 4:5, pages 605-617.
Crossref
Marie Ahnström, Bo Nordenskjöld, Lars Erik Rutqvist, Lambert Skoog & Olle Stål. (2005) Role of cyclin D1 in ErbB2-positive breast cancer and tamoxifen resistance. Breast Cancer Research and Treatment 91:2, pages 145-151.
Crossref
Jui-Wen Huang, Chung-Wai Shiau, Ya-Ting Yang, Samuel K. Kulp, Kuen-Feng Chen, Robert W. Brueggemeier, Charles L. Shapiro & Ching-Shih Chen. (2005) Peroxisome Proliferator-Activated Receptor γ-Independent Ablation of Cyclin D1 by Thiazolidinediones and Their Derivatives in Breast Cancer Cells. Molecular Pharmacology 67:4, pages 1342-1348.
Crossref
Xia Bu, Hava Karsenty Avraham, Xiaoyu Li, Bing Lim, Shuxian Jiang, Yigong Fu, Richard G Pestell & Shalom Avraham. (2005) Mayven induces c-Jun expression and cyclin D1 activation in breast cancer cells. Oncogene 24:14, pages 2398-2409.
Crossref
Huiling Yang, Ruiying Zhao, Heng-Yin Yang & Mong-Hong Lee. (2005) Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1 stability, and suppresses HER2-mediated tumorigenicity. Oncogene 24:11, pages 1924-1935.
Crossref
Toula Bouras, Maofu Fu, Anthony A. Sauve, Fang Wang, Andrew A. Quong, Neil D. Perkins, Ronald T. Hay, Wei Gu & Richard G. Pestell. (2005) SIRT1 Deacetylation and Repression of p300 Involves Lysine Residues 1020/1024 within the Cell Cycle Regulatory Domain 1. Journal of Biological Chemistry 280:11, pages 10264-10276.
Crossref
Musaffe Tuna, Arturo Chavez-Reyes & Ana M Tari. (2005) HER2/neu increases the expression of Wilms' Tumor 1 (WT1) protein to stimulate S-phase proliferation and inhibit apoptosis in breast cancer cells. Oncogene 24:9, pages 1648-1652.
Crossref
Yang Guo, Jyoti Harwalkar, Dennis W Stacey & Masahiro Hitomi. (2004) Destabilization of cyclin D1 message plays a critical role in cell cycle exit upon mitogen withdrawal. Oncogene 24:6, pages 1032-1042.
Crossref
Jinbo Yang, Moitreyee Chatterjee-Kishore, Susan M. Staugaitis, Hannah Nguyen, Karni Schlessinger, David E. Levy & George R. Stark. (2005) Novel Roles of Unphosphorylated STAT3 in Oncogenesis and Transcriptional Regulation. Cancer Research 65:3, pages 939-947.
Crossref
Tatjana M. Trost, Ekkehart U. Lausch, Stephan A. Fees, Steffen Schmitt, Thorsten Enklaar, Dirk Reutzel, Lili R. Brixel, Peter Schmidtke, Marko Maringer, Ilka B. Schiffer, Carolin K. Heimerdinger, Jan G. Hengstler, Gerhard Fritz, Ernst O. Bockamp, Dirk Prawitt, Bernhard U. Zabel & Christian Spangenberg. (2005) Premature Senescence Is a Primary Fail-safe Mechanism of ERBB2-Driven Tumorigenesis in Breast Carcinoma Cells. Cancer Research 65:3, pages 840-849.
Crossref
Zhuo Zhang, Mao Li, Elizabeth R Rayburn, Donald L Hill, Ruiwen Zhang & Hui Wang. (2005) Oncogenes as Novel Targets for Cancer Therapy (Part I). American Journal of PharmacoGenomics 5:3, pages 173-190.
Crossref
Maofu Fu, Chenguang Wang, Zhiping Li, Toshiyuki Sakamaki & Richard G. Pestell. (2004) Minireview: Cyclin D1: Normal and Abnormal Functions. Endocrinology 145:12, pages 5439-5447.
Crossref
Yujiang Zhang, Heng-Yin Yang, Xiao-Chun Zhang, Huiling Yang, Mayli Tsai & Mong-Hong Lee. (2004) Tumor suppressor ARF inhibits HER-2/neu-mediated oncogenic growth. Oncogene 23:42, pages 7132-7143.
Crossref
Gerburg Wulf, Priti Garg, Yih-Cherng Liou, Dirk Iglehart & Kun Ping Lu. (2004) Modeling breast cancer in vivo and ex vivo reveals an essential role of Pin1 in tumorigenesis. The EMBO Journal 23:16, pages 3397-3407.
Crossref
Darren J Fernandes, Claire E Ravenhall, Trudi Harris, Thai Tran, Ross Vlahos & Alastair G Stewart. (2004) Contribution of the p38 MAPK signalling pathway to proliferation in human cultured airway smooth muscle cells is mitogen-specific . British Journal of Pharmacology 142:7, pages 1182-1190.
Crossref
Koichi Okumura, Yuko Hosoe & Noboru Nakajima. (2004) c-Jun and Sp1 family are critical for retinoic acid induction of the lamin A/C retinoic acid-responsive element. Biochemical and Biophysical Research Communications 320:2, pages 487-492.
Crossref
Mark D’Amico, Kongming Wu, Maofu Fu, Mahadev Rao, Chris Albanese, Robert G. Russell, Hanzhou Lian, David Bregman, Michael A. White & Richard G. Pestell. (2004) The Inhibitor of Cyclin-Dependent Kinase 4a/Alternative Reading Frame ( INK4a/ARF ) Locus Encoded Proteins p16INK4a and p19ARF Repress Cyclin D1 Transcription through Distinct cis Elements . Cancer Research 64:12, pages 4122-4130.
Crossref
Michael Hedvat, Anjali Jain, Dennis A Carson, Lorenzo M Leoni, Ganghua Huang, Stuart Holden, Desheng Lu, Maripat Corr, William Fox & David B Agus. (2004) Inhibition of HER-kinase activation prevents ERK-mediated degradation of PPARγ. Cancer Cell 5:6, pages 565-574.
Crossref
Keishi Makino, Chi-Ping Day, Shao-Chun Wang, Yan M Li & Mien-Chie Hung. (2004) Upregulation of IKKα/IKKβ by integrin-linked kinase is required for HER2/neu-induced NF-κB antiapoptotic pathway. Oncogene 23:21, pages 3883-3887.
Crossref
Hye Jin Lee, Sol Kim, Jerry Pelletier & Jungho Kim. (2004) Stimulation of hTAF II 68 (NTD)-mediated transactivation by v-Src . FEBS Letters 564:1-2, pages 188-198.
Crossref
Stacey M. Ivanchuk & James T. Rutka. (2004) The Cell Cycle: Accelerators, Brakes, and Checkpoints. Neurosurgery 54:3, pages 692-700.
Crossref

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