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Cell Growth and Development

RhoE Binds to ROCK I and Inhibits Downstream Signaling

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Pages 4219-4229 | Received 01 Oct 2002, Accepted 26 Feb 2003, Published online: 27 Mar 2023

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Léo Piquet, Terezinha Robbe, Véronique Neaud, Sara Basbous, Stéphanie Rosciglione, Frédéric Saltel & Violaine Moreau. (2018) Rnd3/RhoE expression is regulated by G-actin through MKL1-SRF signaling pathway. Experimental Cell Research 370:2, pages 227-236.
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Yetao Xu, Dan Wu, Jie Liu, Shiyun Huang, Qing Zuo, Xi Xia, Ying Jiang, Sailan Wang, Yanzi Chen, Tianjun Wang & Lizhou Sun. (2018) Downregulated lncRNA HOXA11-AS Affects Trophoblast Cell Proliferation and Migration by Regulating RND3 and HOXA7 Expression in PE. Molecular Therapy - Nucleic Acids 12, pages 195-206.
Crossref
Zhongwei Liu & Raouf A. Khalil. (2018) Evolving mechanisms of vascular smooth muscle contraction highlight key targets in vascular disease. Biochemical Pharmacology 153, pages 91-122.
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Vitor R. Muñoz, Rafael C. Gaspar, Gabriel K. Kuga, Alisson L. da Rocha, Barbara M. Crisol, José D. Botezelli, Igor L. Baptista, Rania A. Mekary, Adelino S. R. da Silva, Dennys E. Cintra, Leandro P. de Moura, Eduardo R. Ropelle & José R. Pauli. (2018) Exercise increases Rho-kinase activity and insulin signaling in skeletal muscle. Journal of Cellular Physiology 233:6, pages 4791-4800.
Crossref
Duy Trong Vien Diep, Kyungki Hong, Triyeng Khun, Mei Zheng, Asad ul-Haq, Hee-Sook Jun, Young-Bum Kim & Kwang-Hoon Chun. (2018) Anti-adipogenic effects of KD025 (SLx-2119), a ROCK2-specific inhibitor, in 3T3-L1 cells. Scientific Reports 8:1.
Crossref
Ye Tu, Lichao Zhang, Lingchang Tong, Yue Wang, Su Zhang, Rongmei Wang, Ling Li & Zhibin Wang. (2018) EFhd2/swiprosin-1 regulates LPS-induced macrophage recruitment via enhancing actin polymerization and cell migration. International Immunopharmacology 55, pages 263-271.
Crossref
Yuan Dai, Weijia Luo & Jiang Chang. (2018) Rho kinase signaling and cardiac physiology. Current Opinion in Physiology 1, pages 14-20.
Crossref
Alexander D. Rhys, Pedro Monteiro, Christopher Smith, Malti Vaghela, Teresa Arnandis, Takuya Kato, Birgit Leitinger, Erik Sahai, Andrew McAinsh, Guillaume Charras & Susana A. Godinho. (2018) Loss of E-cadherin provides tolerance to centrosome amplification in epithelial cancer cells. Journal of Cell Biology 217:1, pages 195-209.
Crossref
Michael S. Samuel & Michael F. Olson. 2018. Encyclopedia of Signaling Molecules. Encyclopedia of Signaling Molecules 4746 4751 .
Huimin Dong, Xi Lin, Yuntao Li, Ronghua Hu, Yang Xu, Xiaojie Guo, Qiong La, Shun Wang, Congcong Fang, Junli Guo, Qi Li, Shanping Mao & Baohui Liu. (2017) Genetic deletion of Rnd3 in neural stem cells promotes proliferation via upregulation of Notch signaling . Oncotarget 8:53, pages 91112-91122.
Crossref
Daniel Brandwein & Zhixiang Wang. (2017) Interaction between Rho GTPases and 14-3-3 Proteins. International Journal of Molecular Sciences 18:10, pages 2148.
Crossref
Yetao Xu, Zhiping Ge, Erbao Zhang, Qing Zuo, Shiyun Huang, Nana Yang, Dan Wu, Yuanyuan Zhang, Yanzi Chen, Haoqin Xu, Huan Huang, Zhiyan Jiang & Lizhou Sun. (2017) The lncRNA TUG1 modulates proliferation in trophoblast cells via epigenetic suppression of RND3. Cell Death & Disease 8:10, pages e3104-e3104.
Crossref
Kaushal Asrani, Akshay Sood, Alba Torres, Dan Georgess, Pornima Phatak, Harsimar Kaur, Amber Dubin, C. Conover TalbotJr.Jr., Loubna Elhelu, Andrew J. Ewald, Bo Xiao, Paul Worley & Tamara L. Lotan. (2017) mTORC1 loss impairs epidermal adhesion via TGF-β/Rho kinase activation. Journal of Clinical Investigation 127:11, pages 4001-4017.
Crossref
Masashi Fujitani, Ryohei Sato & Toshihide Yamashita. (2017) Loss of p73 in ependymal cells during the perinatal period leads to aqueductal stenosis. Scientific Reports 7:1.
Crossref
Yuansheng GaoYuansheng Gao. 2017. Biology of Vascular Smooth Muscle: Vasoconstriction and Dilatation. Biology of Vascular Smooth Muscle: Vasoconstriction and Dilatation 155 167 .
Baohui Liu, Huimin Dong, Xi Lin, Xiangsheng Yang, Xiaojing Yue, Jian Yang, Yuntao Li, Liquan Wu, Xiaonan Zhu, Shenqi Zhang, Daofeng Tian, Junmin Wang, Qiang Cai, Shanping Mao, Qianxue Chen & Jiang Chang. (2016) RND3 promotes Snail 1 protein degradation and inhibits glioblastoma cell migration and invasion. Oncotarget 7:50, pages 82411-82423.
Crossref
Min Shi, Jue Wei, Wen-Ying Meng, Na Wang, Ting Wang & Yu-Gang Wang. (2016) Effects of phased joint intervention on Rho/ROCK expression levels in patients with portal hypertension. Experimental and Therapeutic Medicine 12:3, pages 1618-1624.
Crossref
Sylvie Thuault, Franck Comunale, Jessy Hasna, Mathieu Fortier, Damien Planchon, Nabila Elarouci, Aurélien De Reynies, Stéphane Bodin, Anne Blangy & Cécile Gauthier-Rouvière. (2016) The RhoE/ROCK/ARHGAP25 signaling pathway controls cell invasion by inhibition of Rac activity. Molecular Biology of the Cell 27:17, pages 2653-2661.
Crossref
Lei Wei, Michelle Surma, Stephanie Shi, Nathan Lambert-Cheatham & Jianjian Shi. (2016) Novel Insights into the Roles of Rho Kinase in Cancer. Archivum Immunologiae et Therapiae Experimentalis 64:4, pages 259-278.
Crossref
Jerome W. Breslin, Dayle A. Daines, Travis M. Doggett, Kristine H. Kurtz, Flavia M. Souza‐Smith, Xun E. Zhang, Mack H. Wu & Sarah Y. Yuan. (2016) Rnd3 as a Novel Target to Ameliorate Microvascular Leakage. Journal of the American Heart Association 5:4.
Crossref
Xiaojing YueXi LinTingli YangXiangsheng YangXin YiXuejun JiangXiaoyan LiTianfa LiJunli GuoYuan DaiJianjian ShiLei WeiKeith A. YoukerGuillermo Torre-AmioneYanhong YuKelsey C. AndradeJiang Chang. (2016) Rnd3/RhoE Modulates Hypoxia-Inducible Factor 1α/Vascular Endothelial Growth Factor Signaling by Stabilizing Hypoxia-Inducible Factor 1α and Regulates Responsive Cardiac Angiogenesis. Hypertension 67:3, pages 597-605.
Crossref
Junfeng Tong, Laiji Li, Barbara Ballermann & Zhixiang Wang. (2016) Phosphorylation and Activation of RhoA by ERK in Response to Epidermal Growth Factor Stimulation. PLOS ONE 11:1, pages e0147103.
Crossref
Hiroaki ShimokawaShinichiro SunamuraKimio Satoh. (2016) RhoA/Rho-Kinase in the Cardiovascular System. Circulation Research 118:2, pages 352-366.
Crossref
CHAO SHANG, YANG HONG, YAN GUO, YUN-HUI LIU & YI-XUE XUE. (2016) miR-128 regulates the apoptosis and proliferation of glioma cells by targeting RhoE. Oncology Letters 11:1, pages 904-908.
Crossref
Brad McColl, Ritu Garg, Philippe Riou, Kirsi Riento & Anne J. Ridley. (2016) Rnd3-induced cell rounding requires interaction with Plexin-B2. Journal of Cell Science.
Crossref
Johannes W. Duess, Prem Puri & Jennifer Thompson. (2015) Impaired cytoskeletal arrangements and failure of ventral body wall closure in chick embryos treated with rock inhibitor (Y-27632). Pediatric Surgery International 32:1, pages 45-58.
Crossref
Corey E. Tabit, Qing Mei Wang, Robert Y. L. Zee & James K. Liao. 2016. Biomarkers in Cardiovascular Disease. Biomarkers in Cardiovascular Disease 739 769 .
Michael S. Samuel & Michael F. Olson. 2017. Encyclopedia of Signaling Molecules. Encyclopedia of Signaling Molecules 1 7 .
Wei Jie, Kelsey C. Andrade, Xi Lin, Xiangsheng Yang, Xiaojing Yue & Jiang Chang. 2011. Comprehensive Physiology. Comprehensive Physiology 169 186 .
Katarína Vaškovičová, Emilia Szabadosová, Vladimír Čermák, Aneta Gandalovičová, Lenka Kasalová, Daniel Rösel & Jan Brábek. (2015) PKCα promotes the mesenchymal to amoeboid transition and increases cancer cell invasiveness. BMC Cancer 15:1.
Crossref
Svenja Hartmann, Anne J. Ridley & Susanne Lutz. (2015) The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease. Frontiers in Pharmacology 6.
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Begoña Ballester-Lurbe, Susana González-Granero, Enric Mocholí, Enric Poch, María García-Manzanares, Mara Dierssen, Ignacio Pérez-Roger, José M. García-Verdugo, Rosa M. Guasch & José Terrado. (2014) RhoE deficiency alters postnatal subventricular zone development and the number of calbindin-expressing neurons in the olfactory bulb of mouse. Brain Structure and Function 220:6, pages 3113-3130.
Crossref
Baohui Liu, Xi Lin, Xiangsheng Yang, Huimin Dong, Xiaojing Yue, Kelsey C. Andrade, Zhentao Guo, Jian Yang, Liquan Wu, Xiaonan Zhu, Shenqi Zhang, Daofeng Tian, Junmin Wang, Qiang Cai, Qizuan Chen, Shanping Mao, Qianxue Chen & Jiang Chang. (2015) Downregulation of RND 3/RhoE in glioblastoma patients promotes tumorigenesis through augmentation of notch transcriptional complex activity . Cancer Medicine 4:9, pages 1404-1416.
Crossref
Sarah Van de Velde, Lies De Groef, Ingeborg Stalmans, Lieve Moons & Inge Van Hove. (2015) Towards axonal regeneration and neuroprotection in glaucoma: Rho kinase inhibitors as promising therapeutics. Progress in Neurobiology 131, pages 105-119.
Crossref
Marta Hernández-Sánchez, Enric Poch, Rosa M. Guasch, Joaquín Ortega, Inmaculada López-Almela, Ignacio Palmero & Ignacio Pérez-Roger. (2015) RhoE is required for contact inhibition and negatively regulates tumor initiation and progression. Oncotarget 6:19, pages 17479-17490.
Crossref
Kim Clarke, Thomas Daubon, Nil Turan, Fabienne Soulet, Maihafizah Mohd Zahari, Katie R. Ryan, Sarah Durant, Shan He, John Herbert, John Ankers, John K. Heath, Rolf Bjerkvig, Roy Bicknell, Neil A. Hotchin, Andreas Bikfalvi & Francesco Falciani. (2015) Inference of Low and High-Grade Glioma Gene Regulatory Networks Delineates the Role of Rnd3 in Establishing Multiple Hallmarks of Cancer. PLOS Genetics 11:7, pages e1005325.
Crossref
Simone Schuller, Kjell Sergeant, Jenny Renaut, John J. Callanan, Caitriona Scaife & Jarlath E. Nally. (2015) Comparative proteomic analysis of lung tissue from guinea pigs with leptospiral pulmonary haemorrhage syndrome (LPHS) reveals a decrease in abundance of host proteins involved in cytoskeletal and cellular organization. Journal of Proteomics 122, pages 55-72.
Crossref
Mykhaylo V. Artamonov, Li Jin, Aaron S. Franke, Ko Momotani, Ruoya Ho, Xiu Rong Dong, Mark W. Majesky & Avril V. Somlyo. (2015) Signaling Pathways That Control Rho Kinase Activity Maintain the Embryonic Epicardial Progenitor State. Journal of Biological Chemistry 290:16, pages 10353-10367.
Crossref
Roberta Azzarelli, François Guillemot & Emilie Pacary. (2015) Function and regulation of Rnd proteins in cortical projection neuron migration. Frontiers in Neuroscience 9.
Crossref
Xiangsheng YangTiannan WangXi LinXiaojing YueQiongling WangGuoliang WangQin FuXun AiDavid Y. ChiangChristina Y. MiyakeXander H.T. WehrensJiang Chang. (2015) Genetic Deletion of Rnd3/RhoE Results in Mouse Heart Calcium Leakage Through Upregulation of Protein Kinase A Signaling. Circulation Research 116:1.
Crossref
James K. Liao, Qing Mei Wang, Robert Y. L. Zee & Corey E. Tabit. 2015. Biomarkers in Cardiovascular Disease. Biomarkers in Cardiovascular Disease 1 31 .
Ramesh C. Nayak, Kyung-Hee Chang & Jose A. Cancelas. 2015. The Cytoskeleton in Health and Disease. The Cytoskeleton in Health and Disease 63 85 .
Marjon A Smit, Gianluca Maddalo, Kylie Greig, Linsey M Raaijmakers, Patricia A Possik, Bas van Breukelen, Salvatore Cappadona, Albert JR Heck, AF Maarten Altelaar & Daniel S Peeper. (2014) ROCK 1 is a potential combinatorial drug target for BRAF mutant melanoma . Molecular Systems Biology 10:12.
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Xiangchen Kong, Dan Yan, Jiangming Sun, Xuerui Wu, Hindrik Mulder, Xianxin Hua & Xiaosong Ma. (2014) Glucagon-Like Peptide 1 Stimulates Insulin Secretion via Inhibiting RhoA/ROCK Signaling and Disassembling Glucotoxicity-Induced Stress Fibers. Endocrinology 155:12, pages 4676-4685.
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Olga Gómez, Begoña Ballester-Lurbe, Rosa M. Guasch, Ignacio Pérez-Roger, Empar García-Roselló & José Terrado. (2014) Analysis of RhoE expression in the testis, epididymis and ductus deferens, and the effects of its deficiency in mice. Journal of Anatomy 225:6, pages 583-590.
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Yongjun Tang, Chengping Hu, Huaping Yang, Liming Cao, Yuanyuan Li, Pengbo Deng & Li Huang. (2014) Rnd3 Regulates Lung Cancer Cell Proliferation through Notch Signaling. PLoS ONE 9:11, pages e111897.
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Fang Ke, Lingyun Zhang, Zhaoyuan Liu, Jinlin Liu, Sha Yan, Zhenyao Xu, Jing Bai, Huiyuan Zhu, Fangzhou Lou, Hong Wang, Yufang Shi, Yong Jiang, Bing Su & Honglin Wang. (2014) Autocrine Interleukin-6 Drives Skin-Derived Mesenchymal Stem Cell Trafficking via Regulating Voltage-Gated Ca2+ Channels. Stem Cells 32:10, pages 2799-2810.
Crossref
Ravi K. Singh, Zheng Xia, Christopher S. Bland, Auinash Kalsotra, Marissa A. Scavuzzo, Tomaz Curk, Jernej Ule, Wei Li & Thomas A. Cooper. (2014) Rbfox2-Coordinated Alternative Splicing of Mef2d and Rock2 Controls Myoblast Fusion during Myogenesis. Molecular Cell 55:4, pages 592-603.
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X Yue, X Yang, X Lin, T Yang, X Yi, Y Dai, J Guo, T Li, J Shi, L Wei, G-C Fan, C Chen & J Chang. (2014) Rnd3 haploinsufficient mice are predisposed to hemodynamic stress and develop apoptotic cardiomyopathy with heart failure. Cell Death & Disease 5:6, pages e1284-e1284.
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Bhavin Shah & Andreas W. Püschel. (2014) In vivo functions of small GTPases in neocortical development . Biological Chemistry 395:5, pages 465-476.
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Mari Løset, Matthew P. Johnson, Phillip E. Melton, Wei Ang, Rae-Chi Huang, Trevor A. Mori, Lawrence J. Beilin, Craig Pennell, Linda T. Roten, Ann-Charlotte Iversen, Rigmor Austgulen, Christine E. East, John Blangero, Shaun P. Brennecke & Eric K. Moses. (2014) Preeclampsia and cardiovascular disease share genetic risk factors on chromosome 2q22. Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health 4:2, pages 178-185.
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Atsuko Ishikawa, Waka Omata, William E. AckermanIVIV, Toshiyuki Takeshita, Dale D. Vandré & John M. Robinson. (2014) Cell fusion mediates dramatic alterations in the actin cytoskeleton, focal adhesions, and E-cadherin in trophoblastic cells. Cytoskeleton 71:4, pages 241-256.
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YAJIE ZHU, JITAO ZHOU, HONGWEI XIA, XIANGZHENG CHEN, MENG QIU, JUAN HUANG, SURUI LIU, QIULIN TANG, NAN LANG, ZHEN LIU, MING LIU, YI ZHENG & FENG BI. (2014) The Rho GTPase RhoE is a p53-regulated candidate tumor suppressor in cancer cells. International Journal of Oncology 44:3, pages 896-904.
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Seung-Hwan LeeHu Huang, Kangduk ChoiDae Ho LeeJianjian Shi, Tiemin LiuKwang Hoon ChunJi A. SeoInes S. LimaJanice M. ZabolotnyLei Wei & Young-Bum Kim. (2014) ROCK1 isoform-specific deletion reveals a role for diet-induced insulin resistance. American Journal of Physiology-Endocrinology and Metabolism 306:3, pages E332-E343.
Crossref
Dan Georgess, Marlène Mazzorana, José Terrado, Christine Delprat, Christophe Chamot, Rosa M. Guasch, Ignacio Pérez-Roger, Pierre Jurdic & Irma Machuca-Gayet. (2014) Comparative transcriptomics reveals RhoE as a novel regulator of actin dynamics in bone-resorbing osteoclasts. Molecular Biology of the Cell 25:3, pages 380-396.
Crossref
Rui Mauricio Santos de Araujo, Yasuo Oba, Shingo Kuroda, Eiji Tanaka & Keiji Moriyama. (2014) RhoE regulates actin cytoskeleton organization in human periodontal ligament cells under mechanical stress. Archives of Oral Biology 59:2, pages 187-192.
Crossref
Chi-Ming Liu, Ya-Chin Fan, Yi-Ching Lo, Bin-Nan Wu, Jwu-Lai Yeh & Ing-Jun Chen. (2014) Cyclic guanosine monophosphate-enhancing reduces androgenic extracellular regulated protein kinases-phosphorylation/Rho kinase II-activation in benign prostate hyperplasia. International Journal of Urology 21:1, pages 87-92.
Crossref
A. Nihal Sari, Meltem Kacan, Demet Unsal, Seyhan Sahan Firat, C. Kemal Buharalioglu, Ozden Vezir, Belma Korkmaz, Tuba Cuez, Necmiye Canacankatan, Nehir Sucu, Lokman Ayaz, Lulufer Tamer Gumus, Aysegul Gorur & Bahar Tunctan. (2014) Contribution of RhoA/Rho-kinase/MEK1/ERK1/2/iNOS pathway to ischemia/reperfusion-induced oxidative/nitrosative stress and inflammation leading to distant and target organ injury in rats. European Journal of Pharmacology 723, pages 234-245.
Crossref
Ehsan Amin, Badri Nath Dubey, Si-Cai Zhang, Lothar Gremer, Radovan Dvorsky, Jens M. Moll, Mohamed S. Taha, Luitgard Nagel-Steger, Roland P. Piekorz, Avril V. Somlyo & Mohammad R. Ahmadian. (2013) Rho-kinase: regulation, (dys)function, and inhibition. bchm 394:11, pages 1399-1410.
Crossref
Ramesh C. Nayak, Kyung-Hee Chang, Nataraja-Sarma Vaitinadin & Jose A. Cancelas. (2013) Rho GTPases control specific cytoskeleton-dependent functions of hematopoietic stem cells. Immunological Reviews 256:1, pages 255-268.
Crossref
Jianjian Shi & Lei Wei. (2013) Rho Kinases in Cardiovascular Physiology and Pathophysiology. Journal of Cardiovascular Pharmacology 62:4, pages 341-354.
Crossref
Marta Lonjedo, Enric Poch, Enric Mocholí, Marta Hernández-Sánchez, Carmen Ivorra, Thomas F. Franke, Rosa M. Guasch & Ignacio Pérez-Roger. (2013) The Rho Family Member RhoE Interacts with Skp2 and Is Degraded at the Proteasome during Cell Cycle Progression. Journal of Biological Chemistry 288:43, pages 30872-30882.
Crossref
Marie Morgan-Fisher, John R. Couchman & Atsuko Yoneda. (2013) Phosphorylation and mRNA Splicing of Collapsin Response Mediator Protein-2 Determine Inhibition of Rho-associated Protein Kinase (ROCK) II Function in Carcinoma Cell Migration and Invasion. Journal of Biological Chemistry 288:43, pages 31229-31240.
Crossref
Jonathan DeGeer & Nathalie Lamarche-Vane. (2013) Rho GTPases in neurodegeneration diseases. Experimental Cell Research 319:15, pages 2384-2394.
Crossref
Yizhuo Zhou, Shanshan Li, Qiongping Huang, Lele Xie & Xueliang Zhu. (2013) Nanog suppresses cell migration by downregulating thymosin β4 and Rnd3. Journal of Molecular Cell Biology 5:4, pages 239-249.
Crossref
Xi LinBaohui Liu, Xiangsheng YangXiaojing YueLixia Diao, Jing Wang & Jiang Chang. (2013) Genetic deletion of Rnd3 results in aqueductal stenosis leading to hydrocephalus through up-regulation of Notch signaling. Proceedings of the National Academy of Sciences 110:20, pages 8236-8241.
Crossref
Philippe Riou, Svend Kjær, Ritu Garg, Andrew Purkiss, Roger George, Robert J. Cain, Ganka Bineva, Nicolas Reymond, Brad McColl, Andrew J. Thompson, Nicola O’Reilly, Neil Q. McDonald, Peter J. Parker & Anne J. Ridley. (2013) 14-3-3 Proteins Interact with a Hybrid Prenyl-Phosphorylation Motif to Inhibit G Proteins. Cell 153:3, pages 640-653.
Crossref
Marie Morgan-FisherUlla M. WewerAtsuko Yoneda. (2012) Regulation of ROCK Activity in Cancer. Journal of Histochemistry & Cytochemistry 61:3, pages 185-198.
Crossref
Sy Duong-Quy, Yihua Bei, Zhongmin Liu & Anh Tuan Dinh-Xuan. (2013) Role of Rho-kinase and its inhibitors in pulmonary hypertension. Pharmacology & Therapeutics 137:3, pages 352-364.
Crossref
Undine Gottesbühren, Ritu Garg, Philippe Riou, Brad McColl, Daniel Brayson & Anne J. Ridley. (2013) Rnd3 induces stress fibres in endothelial cells through RhoB. Biology Open 2:2, pages 210-216.
Crossref
Wei Ma, Carmen Chak-Lui Wong, Edmund Kwok-Kwan Tung, Chun Ming Wong & Irene Oi-Lin Ng. (2013) RhoE is frequently down-regulated in hepatocellular carcinoma (HCC) and suppresses HCC invasion through antagonizing the Rho/Rho-Kinase/Myosin phosphatase target pathway. Hepatology 57:1, pages 152-161.
Crossref
Nicola Rath & Michael F Olson. (2012) Rho‐associated kinases in tumorigenesis: re‐considering ROCK inhibition for cancer therapy. EMBO reports 13:10, pages 900-908.
Crossref
Davina Tondeleir, Anja Lambrechts, Matthias Müller, Veronique Jonckheere, Thierry Doll, Drieke Vandamme, Karima Bakkali, Davy Waterschoot, Marianne Lemaistre, Olivier Debeir, Christine Decaestecker, Boris Hinz, An Staes, Evy Timmerman, Niklaas Colaert, Kris Gevaert, Joël Vandekerckhove & Christophe Ampe. (2012) Cells Lacking β-Actin are Genetically Reprogrammed and Maintain Conditional Migratory Capacity*. Molecular & Cellular Proteomics 11:8, pages 255-271.
Crossref
Kensuke Noma, Yasuki Kihara & Yukihito Higashi. (2012) Striking crosstalk of ROCK signaling with endothelial function. Journal of Cardiology 60:1, pages 1-6.
Crossref
Blanca Peris, Susana Gonzalez-Granero, Begoña Ballester-Lurbe, Jose-Manuel García-Verdugo, Ignacio Pérez-Roger, Consuelo Guerri, José Terrado & Rosa M. Guasch. (2012) Neuronal polarization is impaired in mice lacking RhoE expression. Journal of Neurochemistry 121:6, pages 903-914.
Crossref
Manish K. Rana & Rebecca A. Worthylake. (2012) Novel Mechanism for Negatively Regulating Rho-Kinase (ROCK) Signaling through Coronin1B Protein in Neuregulin 1 (NRG-1)-induced Tumor Cell Motility. Journal of Biological Chemistry 287:26, pages 21836-21845.
Crossref
Florence Grise, Sandra Sena, Aurélien Bidaud-Meynard, Jessica Baud, Jean-Baptiste Hiriart, Kassem Makki, Nathalie Dugot-Senant, Cathy Staedel, Paulette Bioulac-Sage, Jessica Zucman-Rossi, Jean Rosenbaum & Violaine Moreau. (2012) Rnd3/RhoE Is down-regulated in hepatocellular carcinoma and controls cellular invasion. Hepatology 55:6, pages 1766-1775.
Crossref
Izumi Oinuma, Kana Kawada, Kiyoka Tsukagoshi & Manabu Negishi. (2012) Rnd1 and Rnd3 targeting to lipid raft is required for p190 RhoGAP activation. Molecular Biology of the Cell 23:8, pages 1593-1604.
Crossref
Yasuyuki Hosono, Tomoya Yamaguchi, Eri Mizutani, Kiyoshi Yanagisawa, Chinatsu Arima, Shuta Tomida, Yukako Shimada, Michiyo Hiraoka, Seiichi Kato, Kohei Yokoi, Motoshi Suzuki & Takashi Takahashi. (2012) MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis. The EMBO Journal 31:2, pages 481-493.
Crossref
Minoru Seto. (2012) Development of Rho kinase inhibitors for pulmonary arterial hypertension. Folia Pharmacologica Japonica 139:6, pages 251-255.
Crossref
Michiro Iizuka, Kazushi Kimura, Shujie Wang, Katsuhiro Kato, Mutsuki Amano, Kozo Kaibuchi & Akira Mizoguchi. (2012) Distinct Distribution and Localization of Rho-kinase in Mouse Epithelial, Muscle and Neural Tissues. Cell Structure and Function 37:2, pages 155-175.
Crossref
Katie R. Ryan, Frances E. Lock, John K. Heath & Neil A. Hotchin. (2012) Plakoglobin-dependent regulation of keratinocyte APOPTOSIS by Rnd3. Journal of Cell Science.
Crossref
Daniela Alfano, Pia Ragno, M. Patrizia Stoppelli & Anne J. Ridley. (2012) RhoB regulates uPAR signalling. Journal of Cell Science.
Crossref
Laura Montani, Damaris Bausch-Fluck, Ana Filipa Domingues, Bernd Wollscheid & João Bettencourt Relvas. 2012. Rho GTPases. Rho GTPases 305 317 .
Nandini V. L. Hayes, Lyne Jossé, C. Mark Smales & Martin J. Carden. (2011) Modulation of Phosducin-Like Protein 3 (PhLP3) Levels Promotes Cytoskeletal Remodelling in a MAPK and RhoA-Dependent Manner. PLoS ONE 6:12, pages e28271.
Crossref
Christophe Guilluy, Rafael Garcia-Mata & Keith Burridge. (2011) Rho protein crosstalk: another social network?. Trends in Cell Biology 21:12, pages 718-726.
Crossref
Yohei Wakita, Tetsuhiro Kakimoto, Hironori Katoh & Manabu Negishi. (2011) The F-BAR Protein Rapostlin Regulates Dendritic Spine Formation in Hippocampal Neurons. Journal of Biological Chemistry 286:37, pages 32672-32683.
Crossref
Kimio Satoh, Yoshihiro Fukumoto & Hiroaki Shimokawa. (2011) Rho-kinase: important new therapeutic target in cardiovascular diseases. American Journal of Physiology-Heart and Circulatory Physiology 301:2, pages H287-H296.
Crossref
Omid Veiseh, Forrest M. Kievit, Richard G. Ellenbogen & Miqin Zhang. (2011) Cancer Cell Invasion: Treatment and Monitoring Opportunities in Nanomedicine. Advanced Drug Delivery Reviews 63:8, pages 582-596.
Crossref
Eve-Ellen Govek, Mary E. Hatten & Linda Van Aelst. (2011) The role of Rho GTPase proteins in CNS neuronal migration. Developmental Neurobiology 71:6, pages 528-553.
Crossref
Pragati Katiyar & Andrew E. Aplin. (2011) FOXD3 Regulates Migration Properties and Rnd3 Expression in Melanoma Cells. Molecular Cancer Research 9:5, pages 545-552.
Crossref
Enric Mocholí, Begoña Ballester-Lurbe, Gloria Arqué, Enric Poch, Blanca Peris, Consuelo Guerri, Mara Dierssen, Rosa M. Guasch, José Terrado & Ignacio Pérez-Roger. (2011) RhoE Deficiency Produces Postnatal Lethality, Profound Motor Deficits and Neurodevelopmental Delay in Mice. PLoS ONE 6:4, pages e19236.
Crossref
Daniel R Croft, Diane Crighton, Michael S Samuel, Filipe C Lourenco, June Munro, Jenifer Wood, Karim Bensaad, Karen H Vousden, Owen J Sansom, Kevin M Ryan & Michael F Olson. (2010) p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival. Cell Research 21:4, pages 666-682.
Crossref
Kwang-Hoon ChunKang-Duk ChoiDae-Ho LeeYoonShin Jung, Robert R. Henry, Theodore P. Ciaraldi & Young-Bum Kim. (2011) In vivo activation of ROCK1 by insulin is impaired in skeletal muscle of humans with type 2 diabetes. American Journal of Physiology-Endocrinology and Metabolism 300:3, pages E536-E542.
Crossref
Emilie Pacary, Julian Heng, Roberta Azzarelli, Philippe Riou, Diogo Castro, Mélanie Lebel-Potter, Carlos Parras, Donald M. Bell, Anne J. Ridley, Maddy Parsons & François Guillemot. (2011) Proneural Transcription Factors Regulate Different Steps of Cortical Neuron Migration through Rnd-Mediated Inhibition of RhoA Signaling. Neuron 69:6, pages 1069-1084.
Crossref
Jianjian Shi, Lumin Zhang & Lei Wei. (2011) Rho-Kinase in Development and Heart Failure: Insights From Genetic Models. Pediatric Cardiology 32:3, pages 297-304.
Crossref
Stéphane Ory & Stéphane Gasman. (2011) Rho GTPases and exocytosis: What are the molecular links?. Seminars in Cell & Developmental Biology 22:1, pages 27-32.
Crossref
Suzanne F.G. van Helden & Peter L. Hordijk. (2011) Podosome regulation by Rho GTPases in myeloid cells. European Journal of Cell Biology 90:2-3, pages 189-197.
Crossref
R Matthew Klein & Paul J Higgins. (2011) A switch in RND3-RHOA signaling is critical for melanoma cell invasion following mutant-BRAF inhibition. Molecular Cancer 10:1, pages 114.
Crossref
Cristina Hidalgo-Carcedo, Steven Hooper, Shahid I. Chaudhry, Peter Williamson, Kevin Harrington, Birgit Leitinger & Erik Sahai. (2010) Collective cell migration requires suppression of actomyosin at cell–cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6. Nature Cell Biology 13:1, pages 49-59.
Crossref
Angela Wirth. (2010) Rho kinase and hypertension. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1802:12, pages 1276-1284.
Crossref
Esben Pedersen & Cord Brakebusch. 2001. eLS. eLS.
Mutsuki Amano, Masanori Nakayama & Kozo Kaibuchi. (2010) Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity. Cytoskeleton 67:9, pages 545-554.
Crossref
Liuh Ling Goh & Ed Manser. (2010) The RhoA GEF Syx Is a Target of Rnd3 and Regulated via a Raf1-Like Ubiquitin-Related Domain. PLoS ONE 5:8, pages e12409.
Crossref
Sarah J. Heasman, Leo M. Carlin, Susan Cox, Tony Ng & Anne J. Ridley. (2010) Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration. Journal of Cell Biology 190:4, pages 553-563.
Crossref
V Sauzeau, I M Berenjeno, C Citterio & X R Bustelo. (2010) A transcriptional cross-talk between RhoA and c-Myc inhibits the RhoA/Rock-dependent cytoskeleton. Oncogene 29:26, pages 3781-3792.
Crossref
Raouf A. Khalil. (2010) Regulation of Vascular Smooth Muscle Function. Colloquium Series on Integrated Systems Physiology: From Molecule to Function 2:1, pages 1-62.
Crossref
Raquel Talens-Visconti, Blanca Peris, Consuelo Guerri & Rosa M. Guasch. (2010) RhoE stimulates neurite-like outgrowth in PC12 cells through inhibition of the RhoA/ROCK-I signalling. Journal of Neurochemistry 112:4, pages 1074-1087.
Crossref
Julian Ik-Tsen Heng, Alain Chariot & Laurent Nguyen. (2010) Molecular layers underlying cytoskeletal remodelling during cortical development. Trends in Neurosciences 33:1, pages 38-47.
Crossref
C. Hahmann & T. Schroeter. (2009) Rho-kinase inhibitors as therapeutics: from pan inhibition to isoform selectivity. Cellular and Molecular Life Sciences 67:2, pages 171-177.
Crossref
Marouan Zarrouk, David Killock & Aleksandar Ivetic. 2010. T-Cell Trafficking. T-Cell Trafficking 83 95 .
Grant R Wickman, Michael S. Samuel, Pamela A Lochhead & Michael F Olson. 2010. The Rho GTPases in Cancer. The Rho GTPases in Cancer 163 192 .
Priam Villalonga, Silvia Fernández de Mattos & Anne J. Ridley. (2009) RhoE Inhibits 4E-BP1 Phosphorylation and eIF4E Function Impairing Cap-dependent Translation. Journal of Biological Chemistry 284:51, pages 35287-35296.
Crossref
J LARTEY & A LÓPEZ BERNAL. (2009) RHO PROTEINS, PREGNANCY AND LABOUR. Fetal and Maternal Medicine Review 20:4, pages 283-299.
Crossref
B. Ballester-Lurbe, E. Poch, E. Mocholí, R.M. Guasch, I. Pérez-Roger & J. Terrado. (2009) RhoE is spatiotemporally regulated in the postnatal mouse CNS. Neuroscience 163:2, pages 586-593.
Crossref
J Lartey & A López Bernal. (2009) RHO protein regulation of contraction in the human uterus. REPRODUCTION 138:3, pages 407-424.
Crossref
Christine T. Brew, Ida Aronchik, Karena Kosco, Jasmine McCammon, Leonard F. Bjeldanes & Gary L. Firestone. (2009) Indole-3-carbinol inhibits MDA-MB-231 breast cancer cell motility and induces stress fibers and focal adhesion formation by activation of Rho kinase activity. International Journal of Cancer 124:10, pages 2294-2302.
Crossref
Jorge A. Pereira, Yves Benninger, Reto Baumann, Ana Filipa Gonçalves, Murat Özçelik, Tina Thurnherr, Nicolas Tricaud, Dies Meijer, Reinhard Fässler, Ueli Suter & João B. Relvas. (2009) Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system. Journal of Cell Biology 185:1, pages 147-161.
Crossref
Florence Grise, Aurélien Bidaud & Violaine Moreau. (2009) Rho GTPases in hepatocellular carcinoma. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1795:2, pages 137-151.
Crossref
R. Matthew Klein & Andrew E. Aplin. (2009) Rnd3 Regulation of the Actin Cytoskeleton Promotes Melanoma Migration and Invasive Outgrowth in Three Dimensions. Cancer Research 69:6, pages 2224-2233.
Crossref
Yuepeng WangXiaoyu Rayne ZhengNadeene RiddickMeredith BrydenWendy BaurXin ZhangHoward K. Surks. (2009) ROCK Isoform Regulation of Myosin Phosphatase and Contractility in Vascular Smooth Muscle Cells. Circulation Research 104:4, pages 531-540.
Crossref
Phyllus Y. Mong & Qin Wang. (2009) Activation of Rho Kinase Isoforms in Lung Endothelial Cells during Inflammation. The Journal of Immunology 182:4, pages 2385-2394.
Crossref
Michael R. Dohn, Meredith V. Brown & Albert B. Reynolds. (2009) An essential role for p120-catenin in Src- and Rac1-mediated anchorage-independent cell growth. Journal of Cell Biology 184:3, pages 437-450.
Crossref
Kai Li, Yuanyuan Lu, Jie Liang, Guanhong Luo, Gui Ren, Xin Wang & Daiming Fan. (2009) RhoE enhances multidrug resistance of gastric cancer cells by suppressing Bax. Biochemical and Biophysical Research Communications 379:2, pages 212-216.
Crossref
Ying-Hua Li, Sharang Ghavampur, Percy Bondallaz, Lena Will, Gabriele Grenningloh & Andreas W. Pu¨schel. (2009) Rnd1 Regulates Axon Extension by Enhancing the Microtubule Destabilizing Activity of SCG10. Journal of Biological Chemistry 284:1, pages 363-371.
Crossref
David Komander, Ritu Garg, Paul T C Wan, Anne J Ridley & David Barford. (2008) Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure. The EMBO Journal 27:23, pages 3175-3185.
Crossref
Inmaculada M. Berenjeno & Xosé R. Bustelo. (2008) Identification of the Rock-dependent transcriptome in rodent fibroblasts. Clinical and Translational Oncology 10:11, pages 726-738.
Crossref
M Fortier, F Comunale, J Kucharczak, A Blangy, S Charrasse & C Gauthier-Rouvière. (2008) RhoE controls myoblast alignment prior fusion through RhoA and ROCK. Cell Death & Differentiation 15:8, pages 1221-1231.
Crossref
Hsiao-Hui Lee & Zee-Fen Chang. (2008) Regulation of RhoA-dependent ROCKII activation by Shp2. Journal of Cell Biology 181:6, pages 999-1012.
Crossref
Michelle J. Muessel, Karen S. Scott, Peter Friedl, Peter Bradding & Andrew J. Wardlaw. (2008) CCL11 and GM-CSF Differentially Use the Rho GTPase Pathway to Regulate Motility of Human Eosinophils in a Three-Dimensional Microenvironment. The Journal of Immunology 180:12, pages 8354-8360.
Crossref
Marieluise Kirchner & Darren E. Higgins. (2008) Inhibition of ROCK activity allows InlF-mediated invasion and increased virulence of Listeria monocytogenes. Molecular Microbiology 68:3, pages 749-767.
Crossref
Ritu GargKirsi RientoNicholas KeepJonathan D. H. MorrisAnne J. Ridley. (2008) N-terminus-mediated dimerization of ROCK-I is required for RhoE binding and actin reorganization. Biochemical Journal 411:2, pages 407-414.
Crossref
Michael F Olson. (2008) Applications for ROCK kinase inhibition. Current Opinion in Cell Biology 20:2, pages 242-248.
Crossref
R. Matthew Klein, Laurie S. Spofford, Ethan V. Abel, Arisa Ortiz & Andrew E. Aplin. (2008) B-RAF Regulation of Rnd3 Participates in Actin Cytoskeletal and Focal Adhesion Organization. Molecular Biology of the Cell 19:2, pages 498-508.
Crossref
Sophie Pinner & Erik Sahai. (2008) PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE. Nature Cell Biology 10:2, pages 127-137.
Crossref
Robert N. Correll, Chunyan Pang, Dana M. Niedowicz, Brian S. Finlin & Douglas A. Andres. (2008) The RGK family of GTP-binding proteins: Regulators of voltage-dependent calcium channels and cytoskeleton remodeling. Cellular Signalling 20:2, pages 292-300.
Crossref
Stéphanie Pellegrin & Harry Mellor. (2007) Actin stress fibres. Journal of Cell Science 120:20, pages 3491-3499.
Crossref
Arthur R. FramptonJr.Jr., Donna B. Stolz, Hiroaki Uchida, William F. Goins, Justus B. Cohen & Joseph C. Glorioso. (2007) Equine Herpesvirus 1 Enters Cells by Two Different Pathways, and Infection Requires the Activation of the Cellular Kinase ROCK1. Journal of Virology 81:20, pages 10879-10889.
Crossref
André Schmandke, Antonio Schmandke & Stephen M. Strittmatter. (2016) ROCK and Rho: Biochemistry and Neuronal Functions of Rho-Associated Protein Kinases. The Neuroscientist 13:5, pages 454-469.
Crossref
Rosa M. Guasch, Ana M. Blanco, Amparo Pérez-Aragó, Rebeca Miñambres, Raquel Talens-Visconti, Blanca Peris & Consuelo Guerri. (2007) RhoE participates in the stimulation of the inflammatory response induced by ethanol in astrocytes. Experimental Cell Research 313:17, pages 3779-3788.
Crossref
J. Lartey, M. Smith, J. Pawade, B. Strachan, H. Mellor & A. López Bernal. (2007) Up-Regulation of Myometrial RHO Effector Proteins (PKN1 and DIAPH1) and CPI-17 (PPP1R14A) Phosphorylation in Human Pregnancy Is Associated with Increased GTP-RHOA in Spontaneous Preterm Labor1. Biology of Reproduction 76:6, pages 971-982.
Crossref
Anastassia Hatzoglou, Isabelle Ader, Anne Splingard, James Flanders, Evelyne Saade, Ingrid Leroy, Sabine Traver, Sandra Aresta & Jean de Gunzburg. (2007) Gem Associates with Ezrin and Acts via the Rho-GAP Protein Gmip to Down-Regulate the Rho Pathway. Molecular Biology of the Cell 18:4, pages 1242-1252.
Crossref
Shunsuke TAWARA & Hiroaki SHIMOKAWA. (2007) Progress of the Study of Rho-kinase and Future Perspective of the InhibitorRhoキナーゼ研究の進展と阻害剤の将来展望. YAKUGAKU ZASSHI 127:3, pages 501-514.
Crossref
Nicola M. Rubenstein, Joseph A. Callahan, Daniel H. Lo & Gary L. Firestone. (2007) Selective glucocorticoid control of Rho kinase isoforms regulate cell–cell interactions. Biochemical and Biophysical Research Communications 354:2, pages 603-607.
Crossref
Martin Vogelsgesang, Alexander Pautsch & Klaus Aktories. (2006) C3 exoenzymes, novel insights into structure and action of Rho-ADP-ribosylating toxins. Naunyn-Schmiedeberg's Archives of Pharmacology 374:5-6, pages 347-360.
Crossref
Michael B. FesslerPatrick G. ArndtIngo JustJerry A. NickKenneth C. Malcolm & G. Scott Worthen. (2006) Dual role for RhoA in suppression and induction of cytokines in the human neutrophil. Blood 109:3, pages 1248-1256.
Crossref
Sarah A. Boswell, Pat P. Ongusaha, Paul Nghiem & Sam W. Lee. (2007) The Protective Role of a Small GTPase RhoE against UVB-induced DNA Damage in Keratinocytes. Journal of Biological Chemistry 282:7, pages 4850-4858.
Crossref
Enric Poch, Rebeca Miñambres, Enric Mocholí, Carmen Ivorra, Amparo Pérez-Aragó, Consuelo Guerri, Ignacio Pérez-Roger & Rosa M. Guasch. (2007) RhoE interferes with Rb inactivation and regulates the proliferation and survival of the U87 human glioblastoma cell line. Experimental Cell Research 313:4, pages 719-731.
Crossref
Cynthia Marie-Claire, Julie Salzmann, Alexandre David, Cindie Courtin, Corinne Canestrelli & Florence Noble. (2007) Rnd family genes are differentially regulated by 3,4-methylenedioxymethamphetamine and cocaine acute treatment in mice brain. Brain Research 1134, pages 12-17.
Crossref
Stephen G. Ball, C. Adrian Shuttleworth & Cay M. Kielty. (2007) Platelet-derived growth factor receptor-α is a key determinant of smooth muscle α-actin filaments in bone marrow-derived mesenchymal stem cells. The International Journal of Biochemistry & Cell Biology 39:2, pages 379-391.
Crossref
Matthew G Gold, David Barford & David Komander. (2006) Lining the pockets of kinases and phosphatases. Current Opinion in Structural Biology 16:6, pages 693-701.
Crossref
Pat P. Ongusaha, Hyung-Gu Kim, Sarah A. Boswell, Anne J. Ridley, Channing J. Der, G. Paolo Dotto, Young-Bum Kim, Stuart A. Aaronson & Sam W. Lee. (2006) RETRACTED: RhoE Is a Pro-Survival p53 Target Gene that Inhibits ROCK I-Mediated Apoptosis in Response to Genotoxic Stress. Current Biology 16:24, pages 2466-2472.
Crossref
Anne J. Ridley. (2006) Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking. Trends in Cell Biology 16:10, pages 522-529.
Crossref
J. Lartey, A. Gampel, J. Pawade, H. Mellor & A. López Bernal. (2006) Expression of RND Proteins in Human Myometrium1. Biology of Reproduction 75:3, pages 452-461.
Crossref
Peter J.M. Stroeken, Belén Alvarez, Jacco van Rheenen, Yvonne M. Wijnands, Dirk Geerts, Kees Jalink & Ed Roos. (2006) Integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the ROCK-I kinase at the plasma membrane. Journal of Cellular Physiology 208:3, pages 620-628.
Crossref

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