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The history of pneumococcal conjugate vaccine development: dose selection

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Pages 1379-1394 | Published online: 09 Jan 2014

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Bruce A. Mungall, Bernard Hoet, Javier Nieto Guevara & Lamine Soumahoro. (2022) A systematic review of invasive pneumococcal disease vaccine failures and breakthrough with higher-valency pneumococcal conjugate vaccines in children. Expert Review of Vaccines 21:2, pages 201-214.
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Abiel Mascareñas de Los Santos, Miguel Angel Rodríguez-Weber, Pedro Sánchez-Márquez, Magali Traskine, Roberto Carreño-Manjarrez, María Yolanda Cervantes-Apolinar, Ana Strezova, Javier Ruiz-Guiñazú, Eduardo Ortega-Barria & Dorota Borys. (2020) Can two different pneumococcal conjugate vaccines be used to complete the infant vaccination series? A randomized trial exploring interchangeability of the 13-valent pneumococcal conjugate vaccine and the pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine. Expert Review of Vaccines 19:11, pages 995-1010.
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Theano Lagousi, Paraskevi Basdeki, Marien I De Jonge & Vana Spoulou. (2020) Understanding host immune responses to pneumococcal proteins in the upper respiratory tract to develop serotype-independent pneumococcal vaccines. Expert Review of Vaccines 19:10, pages 959-972.
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Nicolas Lecrenier, Alen Marijam, Jan Olbrecht, Lamine Soumahoro, Javier Nieto Guevara & Bruce Mungall. (2020) Ten years of experience with the pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (Synflorix) in children. Expert Review of Vaccines 19:3, pages 247-265.
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R. Rupp, D. Hurley, S. Grayson, J. Li, K. Nolan, R.D. McFetridge, J. Hartzel, C. Abeygunawardana, M. Winters, H. Pujar, P. Benner & L. Musey. (2019) A dose ranging study of 2 different formulations of 15-valent pneumococcal conjugate vaccine (PCV15) in healthy infants. Human Vaccines & Immunotherapeutics 15:3, pages 549-559.
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Nicola Principi & Susanna Esposito. (2018) Development of pneumococcal vaccines over the last 10 years. Expert Opinion on Biological Therapy 18:1, pages 7-17.
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Enrico D'Amelio, Simonetta Salemi & Raffaele D'Amelio. (2016) Anti-Infectious Human Vaccination in Historical Perspective. International Reviews of Immunology 35:3, pages 260-290.
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Ho Namkoong, Makoto Ishii, Yohei Funatsu, Yoshifumi Kimizuka, Kazuma Yagi, Takahiro Asami, Takanori Asakura, Shoji Suzuki, Testuro Kamo, Hiroshi Fujiwara, Sadatomo Tasaka, Tomoko Betsuyaku & Naoki Hasegawa. (2016) Theory and strategy for Pneumococcal vaccines in the elderly. Human Vaccines & Immunotherapeutics 12:2, pages 336-343.
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Articles from other publishers (22)

Victor Morais & Norma Suarez. (2022) Conjugation Mechanism for Pneumococcal Glycoconjugate Vaccines: Classic and Emerging Methods. Bioengineering 9:12, pages 774.
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Emily J. Kay, Marta Mauri, Sam J. Willcocks, Timothy A. Scott, Jon Cuccui & Brendan W. Wren. (2022) Engineering a suite of E. coli strains for enhanced expression of bacterial polysaccharides and glycoconjugate vaccines. Microbial Cell Factories 21:1.
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Robert M. F. van der Put, Carolien Smitsman, Alex de Haan, Martin Hamzink, Hans Timmermans, Joost Uittenbogaard, Janny Westdijk, Michiel Stork, Olga Ophorst, Françoise Thouron, Catherine Guerreiro, Philippe J. Sansonetti, Armelle Phalipon & Laurence A. Mulard. (2022) The First-in-Human Synthetic Glycan-Based Conjugate Vaccine Candidate against Shigella . ACS Central Science 8:4, pages 449-460.
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Theano Lagousi, Ioanna Papadatou, Petros Strempas, Elena Chatzikalil & Vana Spoulou. (2021) Pneumococcal Immunization Strategies for High-Risk Pediatric Populations Worldwide: One Size Does Not Fit All. Vaccines 9:12, pages 1390.
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R.K. Lucinde, G. Ong'ayo, C. Houlihan, C. Bottomley, D Goldblatt, J.A.G. Scott & K.E. Gallagher. (2021) Pneumococcal conjugate vaccine dose-ranging studies in humans: A systematic review. Vaccine 39:36, pages 5095-5105.
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Javed & Pintu Kumar Mandal. (2021) Bacterial surface capsular polysaccharides from Streptococcus pneumoniae: A systematic review on structures, syntheses, and glycoconjugate vaccines. Carbohydrate Research 502, pages 108277.
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Hyesung Lee, Ju Hwan Kim, Young June Choe & Ju-Young Shin. (2020) Safety Surveillance of Pneumococcal Vaccine Using Three Algorithms: Disproportionality Methods, Empirical Bayes Geometric Mean, and Tree-Based Scan Statistic. Vaccines 8:2, pages 242.
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Malihe Masomian, Zuleeza Ahmad, Lai Ti Gew & Chit Laa Poh. (2020) Development of Next Generation Streptococcus pneumoniae Vaccines Conferring Broad Protection. Vaccines 8:1, pages 132.
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Zinaida Polonskaya, Paul B Savage, M.G. Finn & Luc Teyton. (2019) High-affinity anti-glycan antibodies: challenges and strategies. Current Opinion in Immunology 59, pages 65-71.
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Hong Wang, Siqiang Li, Chenghe Xiong, Guoxia Jin, Zonggang Chen, Guofeng Gu & Zhongwu Guo. (2019) Biochemical studies of a β-1,4-rhamnoslytransferase from Streptococcus pneumonia serotype 23F . Organic & Biomolecular Chemistry 17:5, pages 1071-1075.
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Theano Lagousi, Paraskevi Basdeki, John Routsias & Vana Spoulou. (2019) Novel Protein-Based Pneumococcal Vaccines: Assessing the Use of Distinct Protein Fragments Instead of Full-Length Proteins as Vaccine Antigens. Vaccines 7:1, pages 9.
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Fadil A. Bidmos, Sara Siris, Camilla A. Gladstone & Paul R. Langford. (2018) Bacterial Vaccine Antigen Discovery in the Reverse Vaccinology 2.0 Era: Progress and Challenges. Frontiers in Immunology 9.
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Thorsten Verch, Jeremiah J Trausch & Mary Shank-Retzlaff. (2018) Principles of vaccine potency assays. Bioanalysis 10:3, pages 163-180.
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Ana Lucia Andrade, Eliane T. Afonso, Ruth Minamisava, Ana Luiza Bierrenbach, Elier B. Cristo, Otaliba L. Morais-Neto, Gabriela M. Policena, Carla M. A. S. Domingues & Cristiana M. Toscano. (2017) Direct and indirect impact of 10-valent pneumococcal conjugate vaccine introduction on pneumonia hospitalizations and economic burden in all age-groups in Brazil: A time-series analysis. PLOS ONE 12:9, pages e0184204.
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Jan Hendriks & Stuart Blume. (2016) Why might regional vaccinology networks fail? The case of the Dutch-Nordic Consortium. Globalization and Health 12:1.
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Johannes Trück, Sena Jawad, David Goldblatt, Lucy Roalfe, Matthew D. Snape, Merryn Voysey & Andrew J. Pollard. (2016) The Antibody Response Following a Booster With Either a 10- or 13-valent Pneumococcal Conjugate Vaccine in Toddlers Primed With a 13-valent Pneumococcal Conjugate Vaccine in Early Infancy. Pediatric Infectious Disease Journal 35:7, pages 787-793.
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Germie P.J.M. van den Dobbelsteen, Kellen C. Faé, Jan Serroyen, Ingrid M. van den Nieuwenhof, Martin Braun, Micha A. Haeuptle, Dominique Sirena, Joerg Schneider, Cristina Alaimo, Gerd Lipowsky, Veronica Gambillara-Fonck, Michael Wacker & Jan T. Poolman. (2016) Immunogenicity and safety of a tetravalent E. coli O-antigen bioconjugate vaccine in animal models. Vaccine 34:35, pages 4152-4160.
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Marco Tamborrini, Nina Geib, Aniebrys Marrero-Nodarse, Maja Jud, Julia Hauser, Celestine Aho, Araceli Lamelas, Armando Zuniga, Gerd Pluschke, Arin Ghasparian & John Robinson. (2015) A Synthetic Virus-Like Particle Streptococcal Vaccine Candidate Using B-Cell Epitopes from the Proline-Rich Region of Pneumococcal Surface Protein A. Vaccines 3:4, pages 850-874.
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Els van Westen, Alienke J. Wijmenga-Monsuur, Harry H. van Dijken, Jacqueline A. M. van Gaans-van den Brink, Betsy Kuipers, Mirjam J. Knol, Guy A. M. Berbers, Elisabeth A. M. Sanders, Nynke Y. Rots & Cécile A. C. M. van Els. (2015) Differential B-Cell Memory Around the 11-Month Booster in Children Vaccinated With a 10- or 13-Valent Pneumococcal Conjugate Vaccine. Clinical Infectious Diseases 61:3, pages 342-349.
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K. Aaron Geno, Gwendolyn L. Gilbert, Joon Young Song, Ian C. Skovsted, Keith P. Klugman, Christopher Jones, Helle B. Konradsen & Moon H. Nahm. (2015) Pneumococcal Capsules and Their Types: Past, Present, and Future. Clinical Microbiology Reviews 28:3, pages 871-899.
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D. Tien Nguyen, Rogier Louwen, Karin Elberse, Geert van Amerongen, Selma Yüksel, Ad Luijendijk, Albert D. M. E. Osterhaus, W. Paul Duprex & Rik L. de Swart. (2015) Streptococcus pneumoniae Enhances Human Respiratory Syncytial Virus Infection In Vitro and In Vivo. PLOS ONE 10:5, pages e0127098.
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Joon Young Song & Hee Jin Cheong. (2014) Pneumococcal vaccine. Journal of the Korean Medical Association 57:9, pages 780.
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