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Review

Modulation of neurotrophic signaling pathways by polyphenols

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Pages 23-42 | Published online: 21 Dec 2015

Keep up to date with the latest research on this topic with citation updates for this article.

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Danyue Zhao, James E. Simon & Qingli Wu. (2020) A critical review on grape polyphenols for neuroprotection: Strategies to enhance bioefficacy. Critical Reviews in Food Science and Nutrition 60:4, pages 597-625.
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
Mario Caruana, Ruben Cauchi & Neville Vassallo. (2016) Putative Role of Red Wine Polyphenols against Brain Pathology in Alzheimer’s and Parkinson’s Disease. Frontiers in Nutrition 3.
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