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Review

Application of supercritical antisolvent method in drug encapsulation: a review

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Pages 1429-1442 | Published online: 06 Jul 2011

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Nurul Amirah Mohd Zaid, Mahendran Sekar, Srinivasa Reddy Bonam, Siew Hua Gan, Pei Teng Lum, M Yasmin Begum, Nur Najihah Izzati Mat Rani, Jaishree Vaijanathappa, Yuan Seng Wu, Vetriselvan Subramaniyan, Neeraj Kumar Fuloria & Shivkanya Fuloria. (2022) Promising Natural Products in New Drug Design, Development, and Therapy for Skin Disorders: An Overview of Scientific Evidence and Understanding Their Mechanism of Action. Drug Design, Development and Therapy 16, pages 23-66.
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Ranjith Kumar Kankala, Biao-Qi Chen, Chen-Guang Liu, Han-Xiao Tang, Shi-Bin Wang & Ai-Zheng Chen. (2018) Solution-enhanced dispersion by supercritical fluids: an ecofriendly nanonization approach for processing biomaterials and pharmaceutical compounds. International Journal of Nanomedicine 13, pages 4227-4245.
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Nguyen Hoai An Le, Hoang Van Phan, Jiaqi Yu, Hak-Kim Chan, Adrian Neild & Tuncay Alan. (2018) Acoustically enhanced microfluidic mixer to synthesize highly uniform nanodrugs without the addition of stabilizers. International Journal of Nanomedicine 13, pages 1353-1359.
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Zheng Zhao, Maobin Xie, Yi Li, Aizheng Chen, Gang Li, Jing Zhang, Huawen Hu, Xinyu Wang & Shipu Li. (2015) Formation of curcumin nanoparticles via solution-enhanced dispersion by supercritical CO2. International Journal of Nanomedicine 10, pages 3171-3181.
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Julieta C. Imperiale, Gabriela Bevilacqua, Paulo de Tarso Vieira e Rosa & Alejandro Sosnik. (2014) Production of pure indinavir free base nanoparticles by a supercritical anti-solvent (SAS) method. Drug Development and Industrial Pharmacy 40:12, pages 1607-1615.
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Shiping Zhan, Liyun Cui, Qicheng Zhao, Jingchang Wang, Shuhua Chen & Shiqiang Ding. (2014) Formation of PLLA-PEG-PLLA Microparticles by Supercritical Antisolvent Process. Particulate Science and Technology 32:1, pages 61-69.
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Claudia Y. Acevedo-Morantes, María T. Acevedo-Morantes, David Suleiman-Rosado & Jaime E. Ramírez-Vick. (2013) Evaluation of the cytotoxic effect of camptothecin solid lipid nanoparticles on MCF7 cells. Drug Delivery 20:8, pages 338-348.
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Ai-Zheng Chen, Guang-Ya Wang, Shi-Bin Wang, Li Li, Yuan-Gang Liu & Chen Zhao. (2012) Formation of methotrexate-PLLA-PEG-PLLA composite microspheres by microencapsulation through a process of suspension-enhanced dispersion by supercritical CO2. International Journal of Nanomedicine 7, pages 3013-3022.
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Mahshid Kalani & Robiah Yunus. (2012) Effect of supercritical fluid density on nanoencapsulated drug particle size using the supercritical antisolvent method. International Journal of Nanomedicine 7, pages 2165-2172.
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Min-Soo Kim, Jeong-Soo Kim, Hee Jun Park, Won Kyung Cho, Kwang-Ho Cha & Sung-Joo Hwang. (2011) Enhanced bioavailability of sirolimus via preparation of solid dispersion nanoparticles using a supercritical antisolvent process. International Journal of Nanomedicine 6, pages 2997-3009.
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Thuany Naiara Silva Laurintino, Evertan Antonio Rebelatto, Jônatas L. Dias, J. Vladimir Oliveira & Ariovaldo Bolzan. (2022) Precipitation of Methionine and Ethyl Cellulose in Carbon Dioxide + Ethanol + Acetic Acid Systems at High Pressures: Phase Equilibrium Data for the GAS Antisolvent Process. SSRN Electronic Journal.
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