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International Journal of Hyperthermia Volume 31, 2015 - Issue 2: (Ultra)sound therapies : harnessing heat and bubbles for therapeutic benefit
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Research Article

Hyperthermia-mediated doxorubicin release from thermosensitive liposomes using MR-HIFU: Therapeutic effect in rabbit Vx2 tumours

Robert M. StaruchPhysical Sciences Platform, Sunnybrook Research Institute, Toronto, Ontario, Canada, ;Department of Medical Biophysics, University of Toronto, Ontario, Canada, and Correspondence[email protected]
,
Kullervo HynynenPhysical Sciences Platform, Sunnybrook Research Institute, Toronto, Ontario, Canada, ;Department of Medical Biophysics, University of Toronto, Ontario, Canada, and
&
Rajiv ChopraPhysical Sciences Platform, Sunnybrook Research Institute, Toronto, Ontario, Canada, ;Department of Medical Biophysics, University of Toronto, Ontario, Canada, and ;Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
Pages 118-133 | Received 13 Aug 2014, Accepted 24 Nov 2014, Published online: 13 Jan 2015

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Muhammad Zubair, Matthew S. Adams & Chris J. Diederich. (2021) Deployable ultrasound applicators for endoluminal delivery of volumetric hyperthermia. International Journal of Hyperthermia 38:1, pages 1188-1204.
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Lukas Christian Sebeke, Pia Rademann, Alexandra Claudia Maul, Sin Yuin Yeo, Juan Daniel Castillo Gómez, Daniel A. Deenen, Patrick Schmidt, Bram de Jager, W. P. M. H. Heemels, Holger Grüll & Edwin Heijman. (2021) Visualization of thermal washout due to spatiotemporally heterogenous perfusion in the application of a model-based control algorithm for MR-HIFU mediated hyperthermia. International Journal of Hyperthermia 38:1, pages 1174-1187.
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Bingbing Cheng, Chenchen Bing, Robert M. Staruch, Sumbul Shaikh, Michelle Wodzak Staruch, Debra Szczepanski, Noelle S. Williams, Theodore W. Laetsch & Rajiv Chopra. (2020) The effect of injected dose on localized tumor accumulation and cardiac uptake of doxorubicin in a Vx2 rabbit tumor model using MR-HIFU mild hyperthermia and thermosensitive liposomes. International Journal of Hyperthermia 37:1, pages 1052-1059.
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Yuk-Wah Tsang, Kwan-Hwa Chi, Cheng-Chung Huang, Mau-Shin Chi, Hsin-Chien Chiang, Kai-Lin Yang, Wen-Tyng Li & Yu-Shan Wang. (2019) Modulated electro-hyperthermia-enhanced liposomal drug uptake by cancer cells. International Journal of Nanomedicine 14, pages 1269-1279.
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Chenchen Bing, Bingbing Cheng, Robert M. Staruch, Joris Nofiele, Michelle Wodzak Staruch, Debra Szczepanski, Alan Farrow-Gillespie, Adeline Yang, Theodore W. Laetsch & Rajiv Chopra. (2019) Breath-hold MR-HIFU hyperthermia: phantom and in vivo feasibility. International Journal of Hyperthermia 36:1, pages 1083-1096.
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Chenchen Bing, Pratik Patel, Robert M. Staruch, Sumbul Shaikh, Joris Nofiele, Michelle Wodzak Staruch, Debra Szczepanski, Noelle S. Williams, Theodore Laetsch & Rajiv Chopra. (2019) Longer heating duration increases localized doxorubicin deposition and therapeutic index in Vx2 tumors using MR-HIFU mild hyperthermia and thermosensitive liposomal doxorubicin. International Journal of Hyperthermia 36:1, pages 195-202.
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Laurence Ho, Mehrdad Bokharaei & Shyh-Dar Li. (2018) Current update of a thermosensitive liposomes composed of DPPC and Brij78. Journal of Drug Targeting 26:5-6, pages 407-419.
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Chenchen Bing, Robert M. Staruch, Matti Tillander, Max O. Köhler, Charles Mougenot, Mika Ylihautala, Theodore W. Laetsch & Rajiv Chopra. (2016) Drift correction for accurate PRF-shift MR thermometry during mild hyperthermia treatments with MR-HIFU. International Journal of Hyperthermia 32:6, pages 673-687.
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Chenchen Bing, Joris Nofiele, Robert Staruch, Michelle Ladouceur-Wodzak, Yonatan Chatzinoff, Ashish Ranjan & Rajiv Chopra. (2015) Localised hyperthermia in rodent models using an MRI-compatible high-intensity focused ultrasound system. International Journal of Hyperthermia 31:8, pages 813-822.
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Gail ter Haar. (2015) Ultrasound: The versatile energy source. International Journal of Hyperthermia 31:2, pages 75-76.
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