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Studies in Humans

Effect of broccoli sprouts on insulin resistance in type 2 diabetic patients: a randomized double-blind clinical trial

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Pages 767-771 | Published online: 26 Apr 2012

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Caroline R. Hill, Armaghan Shafaei, Lois Balmer, Joshua R. Lewis, Jonathan M. Hodgson, A. Harvey Millar & Lauren C. Blekkenhorst. (2023) Sulfur compounds: From plants to humans and their role in chronic disease prevention. Critical Reviews in Food Science and Nutrition 63:27, pages 8616-8638.
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Jiaying Wu, Shumao Cui, Junsheng Liu, Xin Tang, Jianxin Zhao, Hao Zhang, Bingyong Mao & Wei Chen. (2023) The recent advances of glucosinolates and their metabolites: Metabolism, physiological functions and potential application strategies. Critical Reviews in Food Science and Nutrition 63:20, pages 4217-4234.
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Ali Ali Redha, Luciana Torquati, Faye Langston, Geoffrey R. Nash, Michael J. Gidley & Daniel Cozzolino. (2023) Determination of glucosinolates and isothiocyanates in glucosinolate-rich vegetables and oilseeds using infrared spectroscopy: A systematic review. Critical Reviews in Food Science and Nutrition 0:0, pages 1-17.
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Azza M. El-Wakf, Abeer E. Abdrabouh & Azza M. Elgarieb. (2019) Effectiveness of steamed and cooked broccoli to attenuate bone marrow injury and suppressed haemopoiesis in male rats exposed to petrol vapours. International Journal of Environmental Studies 76:1, pages 102-117.
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Munawar Abbas, Farhan Saeed, Faqir Muhammad Anjum, Muhammad Afzaal, Tabussam Tufail, Muhammad Shakeel Bashir, Adnan Ishtiaq, Shahzad Hussain & Hafiz Ansar Rasul Suleria. (2017) Natural polyphenols: An overview. International Journal of Food Properties 20:8, pages 1689-1699.
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Sho-Ichi Yamagishi & Takanori Matsui. (2016) Protective role of sulphoraphane against vascular complications in diabetes. Pharmaceutical Biology 54:10, pages 2329-2339.
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Venkidasamy Baskar, Se Won Park & Shivraj Hariram Nile. (2016) An Update on Potential Perspectives of Glucosinolates on Protection against Microbial Pathogens and Endocrine Dysfunctions in Humans. Critical Reviews in Food Science and Nutrition 56:13, pages 2231-2249.
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Arantxa Rodriguez-Casado. (2016) The Health Potential of Fruits and Vegetables Phytochemicals: Notable Examples. Critical Reviews in Food Science and Nutrition 56:7, pages 1097-1107.
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Daniel Villarreal-García, Pedro A. Alanís-Garza, María del Rosario Cuéllar-Villarreal, Mónica Redondo-Gil, José Luis Mora-Nieves & Daniel A. Jacobo-Velázquez. (2015) Effects of different defrosting methods on the stability of bioactive compounds and consumer acceptability of frozen broccoli. CyTA - Journal of Food 13:2, pages 312-320.
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Crossref
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Crossref
RAKESH SHARMA, SUNAKSHI GAUTAM & HAMID HAMID. (2021) Effect of MAP on shelf-life of broccoli and cabbage grown under natural farming. The Indian Journal of Agricultural Sciences 91:9.
Crossref
Aisha Gambo, Indres Moodley, Musa Babashani & Tesleem K. Babalola. (2021) Impact of Moringa Oleifera leaves supplementation on quality of life of people living with HIV: A double-blind randomized controlled trial. Quality of Life Research 30:9, pages 2563-2571.
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Sarah Hartwick BjorkmanRenata Oliveira Pereira. (2021) The Interplay Between Mitochondrial Reactive Oxygen Species, Endoplasmic Reticulum Stress, and Nrf2 Signaling in Cardiometabolic Health. Antioxidants & Redox Signaling 35:4, pages 252-269.
Crossref
Gil Zandani, Sarit Anavi-Cohen, Nina Tsybina-Shimshilashvili, Noa Sela, Abraham Nyska & Zecharia Madar. (2021) Broccoli Florets Supplementation Improves Insulin Sensitivity and Alters Gut Microbiome Population—A Steatosis Mice Model Induced by High-Fat Diet. Frontiers in Nutrition 8.
Crossref
Ahmed Ismaeel, K. Leigh Greathouse, Nathan Newton, Dimitrios Miserlis, Evlampia Papoutsi, Robert S. Smith, Jack L. Eidson, David L. Dawson, Craig W. Milner, Robert J. Widmer, William T. Bohannon & Panagiotis Koutakis. (2021) Phytochemicals as Therapeutic Interventions in Peripheral Artery Disease. Nutrients 13:7, pages 2143.
Crossref
Peter RosePhilip Keith MooreMatthew WhitemanCharlotte KirkYi-Zhun Zhu. (2021) Diet and Hydrogen Sulfide Production in Mammals. Antioxidants & Redox Signaling 34:17, pages 1378-1393.
Crossref
Qi Wang & Yongping Bao. (2021) Nanodelivery of natural isothiocyanates as a cancer therapeutic. Free Radical Biology and Medicine 167, pages 125-140.
Crossref
Jed W. Fahey & Thomas W. Kensler. (2021) The Challenges of Designing and Implementing Clinical Trials With Broccoli Sprouts… and Turning Evidence Into Public Health Action. Frontiers in Nutrition 8.
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Andrea Da Porto, Alessandro Cavarape, GianLuca Colussi, Viviana Casarsa, Cristiana Catena & Leonardo A. Sechi. (2021) Polyphenols Rich Diets and Risk of Type 2 Diabetes. Nutrients 13:5, pages 1445.
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Eugenia Piragine, Lorenzo Flori, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Eleonora Pagnotta, Roberto Matteo, Luca Lazzeri, Alma Martelli, Vincenzo Miragliotta, Andrea Pirone, Lara Testai & Vincenzo Calderone. (2020) Eruca sativa Mill . seed extract promotes anti‐obesity and hypoglycemic effects in mice fed with a high‐fat diet . Phytotherapy Research 35:4, pages 1983-1990.
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Mirjana Mihailović, Svetlana Dinić, Jelena Arambašić Jovanović, Aleksandra Uskoković, Nevena Grdović & Melita Vidaković. (2021) The Influence of Plant Extracts and Phytoconstituents on Antioxidant Enzymes Activity and Gene Expression in the Prevention and Treatment of Impaired Glucose Homeostasis and Diabetes Complications. Antioxidants 10:3, pages 480.
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Crossref
Haiyan Gao. 2021. Handbook of Dietary Phytochemicals. Handbook of Dietary Phytochemicals 1369 1400 .
Albino Carrizzo, Carmine Izzo, Maurizio Forte, Eduardo Sommella, Paola Di Pietro, Eleonora Venturini, Michele Ciccarelli, Gennaro Galasso, Speranza Rubattu, Petro Campiglia, Sebastiano Sciarretta, Giacomo Frati & Carmine Vecchione. (2020) A Novel Promising Frontier for Human Health: The Beneficial Effects of Nutraceuticals in Cardiovascular Diseases. International Journal of Molecular Sciences 21:22, pages 8706.
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Ewa Szczesny-Malysiak, Marta Stojak, Roberto Campagna, Marek Grosicki, Marek Jamrozik, Patrycja Kaczara & Stefan Chlopicki. (2020) Bardoxolone Methyl Displays Detrimental Effects on Endothelial Bioenergetics, Suppresses Endothelial ET-1 Release, and Increases Endothelial Permeability in Human Microvascular Endothelium. Oxidative Medicine and Cellular Longevity 2020, pages 1-16.
Crossref
Wael El-Shahat, Mohamed EL-Adl, Mohamed Hamed & Youssef El-Saedy. (2020) The protective effect of sulforaphane in rats fed on high cholesterol high fructose diets. Mansoura Veterinary Medical Journal 21:3, pages 85-90.
Crossref
Montserrat Esteve. (2020) Mechanisms Underlying Biological Effects of Cruciferous Glucosinolate-Derived Isothiocyanates/Indoles: A Focus on Metabolic Syndrome. Frontiers in Nutrition 7.
Crossref
Sylvia Maina, Gerald Misinzo, Gaymary Bakari & Ho-Youn Kim. (2020) Human, Animal and Plant Health Benefits of Glucosinolates and Strategies for Enhanced Bioactivity: A Systematic Review. Molecules 25:16, pages 3682.
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Yoko Yagishita, Tonibelle N. Gatbonton-Schwager, Melissa L. McCallum & Thomas W. Kensler. (2020) Current Landscape of NRF2 Biomarkers in Clinical Trials. Antioxidants 9:8, pages 716.
Crossref
Junduo Wu, Xiaodan Sun, Ziping Jiang, Jun Jiang, Linlin Xu, Ao Tian, Xuechun Sun, Huali Meng, Ying Li, Wenlin Huang, Ye Jia & Hao Wu. (2020) Protective role of NRF2 in macrovascular complications of diabetes. Journal of Cellular and Molecular Medicine 24:16, pages 8903-8917.
Crossref
Thanh Ninh Le, Chiu-Hsia Chiu & Pao-Chuan Hsieh. (2020) Bioactive Compounds and Bioactivities of Brassica oleracea L. var. Italica Sprouts and Microgreens: An Updated Overview from a Nutraceutical Perspective. Plants 9:8, pages 946.
Crossref
Giulia Apprato, Camilla Fiz, Isabella Fusano, Loredana Bergandi & Francesca Silvagno. (2020) Natural Epigenetic Modulators of Vitamin D Receptor. Applied Sciences 10:12, pages 4096.
Crossref
Khara Lucius. (2020) Botanical Medicine and Phytochemicals in Healthy Aging and Longevity—Part 2. Alternative and Complementary Therapies 26:2, pages 70-78.
Crossref
Sarai Quirante-Moya, Paula García-Ibañez, Francisco Quirante-Moya, Débora Villaño & Diego A. Moreno. (2020) The Role of Brassica Bioactives on Human Health: Are We Studying It the Right Way?. Molecules 25:7, pages 1591.
Crossref
Nadia Mazarakis, Kenneth Snibson, Paul V. Licciardi & Tom C. Karagiannis. (2020) The potential use of l-sulforaphane for the treatment of chronic inflammatory diseases: A review of the clinical evidence. Clinical Nutrition 39:3, pages 664-675.
Crossref
Alma MartelliValentina CitiLara TestaiSimone BrogiVincenzo Calderone. (2020) Organic Isothiocyanates as Hydrogen Sulfide Donors. Antioxidants & Redox Signaling 32:2, pages 110-144.
Crossref
Geetha Shree Nagraj, Anita Chouksey, Swarna Jaiswal & Amit K. Jaiswal. 2020. Nutritional Composition and Antioxidant Properties of Fruits and Vegetables. Nutritional Composition and Antioxidant Properties of Fruits and Vegetables 5 17 .
Haiyan Gao. 2020. Handbook of Dietary Phytochemicals. Handbook of Dietary Phytochemicals 1 33 .
Kyeong-Mi Choi & Hwan-Soo Yoo. (2019) Amelioration of Hyperglycemia-Induced Nephropathy by 3,3′-Diindolylmethane in Diabetic Mice. Molecules 24:24, pages 4474.
Crossref
Zahra Bahadoran, Parvin Mirmiran, Khosrow Kashfi & Asghar Ghasemi. (2019) The Principles of Biomedical Scientific Writing: Title. International Journal of Endocrinology and Metabolism 17:4.
Crossref
Christine A. Houghton. (2019) Sulforaphane: Its “Coming of Age” as a Clinically Relevant Nutraceutical in the Prevention and Treatment of Chronic Disease. Oxidative Medicine and Cellular Longevity 2019, pages 1-27.
Crossref
Yoko Yagishita, Jed W. Fahey, Albena T. Dinkova-Kostova & Thomas W. Kensler. (2019) Broccoli or Sulforaphane: Is It the Source or Dose That Matters?. Molecules 24:19, pages 3593.
Crossref
Paula Aranaz, David Navarro-Herrera, Ana Romo-Hualde, María Zabala, Miguel López-Yoldi, Carolina González-Ferrero, Ana Gloria Gil, J. Alfredo Martinez, José Luis Vizmanos, Fermín I. Milagro & Carlos J. González-Navarro. (2019) Broccoli extract improves high fat diet-induced obesity, hepatic steatosis and glucose intolerance in Wistar rats. Journal of Functional Foods 59, pages 319-328.
Crossref
Annette Petersen, Christoph Crocoll & Barbara Ann Halkier. (2019) De novo production of benzyl glucosinolate in Escherichia coli. Metabolic Engineering 54, pages 24-34.
Crossref
Zhi-Dong Ge, Qingquan Lian, Xiaowen Mao & Zhengyuan Xia. (2019) Current Status and Challenges of NRF2 as a Potential Therapeutic Target for Diabetic Cardiomyopathy. International Heart Journal 60:3, pages 512-520.
Crossref
Bong-Shin KwakDahyun HwangSue Jung LeeHyuk-Jun ChoiHo-Young ParkKwang-Soon Shin. (2019) Rhamnogalacturonan-I-Type Polysaccharide Purified from Broccoli Exerts Anti-Metastatic Activities Via Innate Immune Cell Activation. Journal of Medicinal Food 22:5, pages 451-459.
Crossref
Rupbansraaj Bathmanath, Yasmin Amira Che Yahya, Mashitah Mohd Yusoff & Jaya Vejayan. (2019) Utilizing Coagulant Plants in the Development of Functional Dairy Foods and Beverages: A Mini Review. Journal of Biological Sciences 19:3, pages 259-271.
Crossref
Hoai Tran, Monika Schreiner, Nina Schlotz & Evelyn Lamy. (2019) Short-Term Dietary Intervention with Cooked but Not Raw Brassica Leafy Vegetables Increases Telomerase Activity in CD8+ Lymphocytes in a Randomized Human Trial. Nutrients 11:4, pages 786.
Crossref
Ángel Abellán, Raúl Domínguez-Perles, Diego Moreno & Cristina García-Viguera. (2019) Sorting out the Value of Cruciferous Sprouts as Sources of Bioactive Compounds for Nutrition and Health. Nutrients 11:2, pages 429.
Crossref
Emine KOÇYİĞİT & Eda KÖKSAL. (2019) Sülforafan, Potansiyel Etki Mekanizması ve Sağlıkla İlişkisi. Sağlık Bilimleri ve Meslekleri Dergisi.
Crossref
Noha M. Shawky, George S.G. Shehatou, Ghada M. Suddek & Nariman M. Gameil. (2019) Comparison of the effects of sulforaphane and pioglitazone on insulin resistance and associated dyslipidemia, hepatosteatosis, and endothelial dysfunction in fructose-fed rats. Environmental Toxicology and Pharmacology 66, pages 43-54.
Crossref
Hassan Rasouli, Seyed Mohammad-Bagher Hosseini-Ghazvini & Reza Khodarahmi. 2019. 85 122 .
S. Esakkimuthu, S. Sylvester Darvin, S. Mutheeswaran, M. Gabriel Paulraj, P. Pandikumar, S. Ignacimuthu & N. A. Al-Dhabi. (2018) A study on food-medicine continuum among the non-institutionally trained siddha practitioners of Tiruvallur district, Tamil Nadu, India. Journal of Ethnobiology and Ethnomedicine 14:1.
Crossref
Annette Petersen, Cuiwei Wang, Christoph Crocoll & Barbara Ann Halkier. (2018) Biotechnological approaches in glucosinolate production. Journal of Integrative Plant Biology 60:12, pages 1231-1248.
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Paulina Ormazabal, Beatrice Scazzocchio, Rosaria Varì, Carmela Santangelo, Massimo D’Archivio, Gianfranco Silecchia, Annunziata Iacovelli, Claudio Giovannini & Roberta Masella. (2018) Effect of protocatechuic acid on insulin responsiveness and inflammation in visceral adipose tissue from obese individuals: possible role for PTP1B. International Journal of Obesity 42:12, pages 2012-2021.
Crossref
Manuel Matzinger, Katrin Fischhuber & Elke H. Heiss. (2018) Activation of Nrf2 signaling by natural products-can it alleviate diabetes?. Biotechnology Advances 36:6, pages 1738-1767.
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María Iñiguez, Patricia Pérez-Matute, María Jesús Villanueva-Millán, Emma Recio-Fernández, Irene Roncero-Ramos, Margarita Pérez-Clavijo & José-Antonio Oteo. (2018) Agaricus bisporus supplementation reduces high-fat diet-induced body weight gain and fatty liver development. Journal of Physiology and Biochemistry 74:4, pages 635-646.
Crossref
Marc Sim, Lauren C. Blekkenhorst, Joshua R. Lewis, Catherine P. Bondonno, Amanda Devine, Kun Zhu, Richard J. Woodman, Richard L. Prince & Jonathan M. Hodgson. (2018) Vegetable and fruit intake and injurious falls risk in older women: a prospective cohort study. British Journal of Nutrition 120:8, pages 925-934.
Crossref
Antonia Wiegering, Ulrich Rüther & Christoph Gerhardt. (2018) The ciliary protein Rpgrip1l in development and disease. Developmental Biology 442:1, pages 60-68.
Crossref
Shanshan Zhou, Jiqun Wang, Xia Yin, Ying Xin, Zhiguo Zhang, Taixing Cui, Jun Cai, Yang Zheng, Quan Liu & Lu Cai. (2018) Nrf2 expression and function, but not MT expression, is indispensable for sulforaphane-mediated protection against intermittent hypoxia-induced cardiomyopathy in mice. Redox Biology 19, pages 11-21.
Crossref
Lauren Housley, Armando Alcazar Magana, Anna Hsu, Laura M. Beaver, Carmen P. Wong, Jan F. Stevens, Jaewoo Choi, Yuan Jiang, Deborah Bella, David E. Williams, Claudia S. Maier, Jackilen Shannon, Roderick H. Dashwood & Emily Ho. (2018) Untargeted Metabolomic Screen Reveals Changes in Human Plasma Metabolite Profiles Following Consumption of Fresh Broccoli Sprouts. Molecular Nutrition & Food Research 62:19.
Crossref
Teresa Oliviero, Ruud Verkerk & Matthijs Dekker. (2018) Isothiocyanates from Brassica Vegetables—Effects of Processing, Cooking, Mastication, and Digestion . Molecular Nutrition & Food Research 62:18.
Crossref
Dushani L. Palliyaguru, Jian‐Min Yuan, Thomas W. Kensler & Jed W. Fahey. (2018) Isothiocyanates: Translating the Power of Plants to People. Molecular Nutrition & Food Research 62:18.
Crossref
Bijal Patel, Giovanni E. Mann & Sarah J. Chapple. (2018) Concerted redox modulation by sulforaphane alleviates diabetes and cardiometabolic syndrome. Free Radical Biology and Medicine 122, pages 150-160.
Crossref
Le Ma, Gang Liu, Laura Sampson, Walter C Willett, Frank B Hu & Qi Sun. (2018) Dietary glucosinolates and risk of type 2 diabetes in 3 prospective cohort studies. The American Journal of Clinical Nutrition 107:4, pages 617-625.
Crossref
Qin M. Chen & Anthony J. Maltagliati. (2018) Nrf2 at the heart of oxidative stress and cardiac protection. Physiological Genomics 50:2, pages 77-97.
Crossref
Yan Xu, Jian-Fei Fu, Jia-Hui Chen, Zhuang-Wei Zhang, Zu-Quan Zou, Li-Yuan Han, Qi-Hang Hua, Jin-Shun Zhao, Xiao-Hong Zhang & Yu-Juan Shan. (2018) Sulforaphane ameliorates glucose intolerance in obese mice via the upregulation of the insulin signaling pathway . Food & Function 9:9, pages 4695-4701.
Crossref
Débora Z. do Prado, Bruna L. Capoville, Clarissa H.O. Delgado, Julia C.A. Heliodoro, Mayara R. Pivetta, Milene S. Pereira, Mirella R. Zanutto, Paula K. Novelli, Valesca C.B. Francisco & Luciana F. Fleuri. 2018. Alternative and Replacement Foods. Alternative and Replacement Foods 95 140 .
Shelley Suter & Mark Lucock. (2017) Xenohormesis: Applying Evolutionary Principles to Contemporary Health Issues. Exploratory Research and Hypothesis in Medicine 2:4, pages 1-7.
Crossref
Albena T. Dinkova-Kostova, Jed W. Fahey, Rumen V. Kostov & Thomas W. Kensler. (2017) KEAP1 and done? Targeting the NRF2 pathway with sulforaphane. Trends in Food Science & Technology 69, pages 257-269.
Crossref
Edoardo Capuano, Matthijs Dekker, Ruud Verkerk & Teresa Oliviero. (2017) Food as Pharma? The Case of Glucosinolates. Current Pharmaceutical Design 23:19, pages 2697-2721.
Crossref
Pilar Buil-Cosiales, Miguel Martinez-Gonzalez, Miguel Ruiz-Canela, Javier Díez-Espino, Ana García-Arellano & Estefania Toledo. (2017) Consumption of Fruit or Fiber-Fruit Decreases the Risk of Cardiovascular Disease in a Mediterranean Young Cohort. Nutrients 9:3, pages 295.
Crossref
Zhenxian Han, Qian Xu, Changfu Li & Hong Zhao. (2017) Effects of sulforaphane on neural stem cell proliferation and differentiation. genesis 55:3, pages e23022.
Crossref
Hendrik Gremmels, Olivier G. de Jong, Diënty H. Hazenbrink, Joost O. Fledderus & Marianne C. Verhaar. (2017) The Transcription Factor Nrf2 Protects Angiogenic Capacity of Endothelial Colony-Forming Cells in High-Oxygen Radical Stress Conditions. Stem Cells International 2017, pages 1-11.
Crossref
Bingdi Yan, Jin Ren, Qinghua Zhang, Rong Gao, Fenglian Zhao, Junduo Wu & Junling Yang. (2017) Antioxidative Effects of Natural Products on Diabetic Cardiomyopathy. Journal of Diabetes Research 2017, pages 1-13.
Crossref
Valentina Guzmán-Pérez, Christiane Bumke-Vogt, Monika Schreiner, Inga Mewis, Andrea Borchert & Andreas F. H. Pfeiffer. (2016) Benzylglucosinolate Derived Isothiocyanate from Tropaeolum majus Reduces Gluconeogenic Gene and Protein Expression in Human Cells. PLOS ONE 11:9, pages e0162397.
Crossref
Xiujuan Jia, Lina Zhong, Yan Song, Yi Hu, Guimei Wang & Shuqin Sun. (2016) Consumption of citrus and cruciferous vegetables with incident type 2 diabetes mellitus based on a meta-analysis of prospective study. Primary Care Diabetes 10:4, pages 272-280.
Crossref
Noha M. Shawky, Prahalathan Pichavaram, George S.G. Shehatou, Ghada M. Suddek, Nariman M. Gameil, John Y. Jun & Lakshman Segar. (2016) Sulforaphane improves dysregulated metabolic profile and inhibits leptin-induced VSMC proliferation: Implications toward suppression of neointima formation after arterial injury in western diet-fed obese mice. The Journal of Nutritional Biochemistry 32, pages 73-84.
Crossref
M. Okulicz & I. Hertig. (2016) Acute sulforaphane action exhibits hormonal and metabolic activities in the rat: in vivo and in vitro studies. Czech Journal of Animal Science 61:1, pages 22-31.
Crossref
Yusuke UshidaChutinan Boonyapichest, Hiroyuki SuganumaMitsuru Tanaka & Toshiro Matsui. (2016) Paracellular Transport of Sulforaphane across Caco-2 Cell Monolayers. Food Science and Technology Research 22:1, pages 127-134.
Crossref
Allison J Greaney, Nolan K Maier, Stephen H Leppla & Mahtab Moayeri. (2016) Sulforaphane inhibits multiple inflammasomes through an Nrf2-independent mechanism. Journal of Leukocyte Biology 99:1, pages 189-199.
Crossref
Yoko Yagishita, Akira Uruno & Masayuki Yamamoto. 2016. Molecular Nutrition and Diabetes. Molecular Nutrition and Diabetes 331 348 .
Arezou Rezaei, Azad Farzadfard, Atefe Amirahmadi, Maasoomeh Alemi & Mitra Khademi. (2015) Diabetes mellitus and its management with medicinal plants: A perspective based on Iranian research. Journal of Ethnopharmacology 175, pages 567-616.
Crossref
Shanshan Zhou, Jingpeng Jin, Tao Bai, Leroy R. SachlebenJrJr, Lu Cai & Yang Zheng. (2015) Potential drugs which activate nuclear factor E2-related factor 2 signaling to prevent diabetic cardiovascular complications: A focus on fumaric acid esters. Life Sciences 134, pages 56-62.
Crossref
Angélica Saraí Jiménez-Osorio, Susana González-Reyes & José Pedraza-Chaverri. (2015) Natural Nrf2 activators in diabetes. Clinica Chimica Acta 448, pages 182-192.
Crossref
Beatrice Scazzocchio, Rosaria Varì, Carmelina Filesi, Ilaria Del Gaudio, Massimo D'Archivio, Carmela Santangelo, Annunziata Iacovelli, Fabio Galvano, Francesca Romana Pluchinotta, Claudio Giovannini & Roberta Masella. (2015) Protocatechuic acid activates key components of insulin signaling pathway mimicking insulin activity. Molecular Nutrition & Food Research 59:8, pages 1472-1481.
Crossref
V. Nagaveni & S. Prabhakar. (2015) Insights into the binding sites of sulforaphane on insulin studied by electrospray ionization mass spectrometry. Rapid Communications in Mass Spectrometry 29:12, pages 1155-1164.
Crossref
Guoguo Shang, Xinjun Tang, Pan Gao, Fanli Guo, Hongpeng Liu, Zhonghua Zhao, Qi Chen, Tao Jiang, Nong Zhang & Hui Li. (2015) Sulforaphane attenuation of experimental diabetic nephropathy involves GSK-3 beta/Fyn/Nrf2 signaling pathway. The Journal of Nutritional Biochemistry 26:6, pages 596-606.
Crossref
Carrie Waterman, Patricio Rojas-Silva, Tugba Boyunegmez Tumer, Peter Kuhn, Allison J. Richard, Shawna Wicks, Jacqueline M. Stephens, Zhong Wang, Randy Mynatt, William Cefalu & Ilya Raskin. (2015) Isothiocyanate-rich Moringa oleifera extract reduces weight gain, insulin resistance, and hepatic gluconeogenesis in mice . Molecular Nutrition & Food Research 59:6, pages 1013-1024.
Crossref
Jeong-Hwa HanHye-Jin LeeTae-Seok KimMyung-Hee Kang. (2015) The effect of glutathione S-transferase M1 and T1 polymorphisms on blood pressure, blood glucose, and lipid profiles following the supplementation of kale ( Brassica oleracea acephala ) juice in South Korean subclinical hypertensive patients . Nutrition Research and Practice 9:1, pages 49.
Crossref
Alessandra Masci, Roberto Mattioli, Paolo Costantino, Simona Baima, Giorgio Morelli, Pasqualina Punzi, Cesare Giordano, Alessandro Pinto, Lorenzo Maria Donini, Maria d’Erme & Luciana Mosca. (2015) Neuroprotective Effect of Brassica oleracea Sprouts Crude Juice in a Cellular Model of Alzheimer’s Disease . Oxidative Medicine and Cellular Longevity 2015, pages 1-17.
Crossref
Chiara Cipollina. (2015) Endogenous Generation and Signaling Actions of Omega-3 Fatty Acid Electrophilic Derivatives. BioMed Research International 2015, pages 1-13.
Crossref
Bernhard HJ Juurlink, Haya J Azouz, Alaa MZ Aldalati, Basmah MH AlTinawi & Paul Ganguly. (2014) Hydroxybenzoic acid isomers and the cardiovascular system. Nutrition Journal 13:1.
Crossref
Xin Jiang, Yang Bai, Zhiguo Zhang, Ying Xin & Lu Cai. (2014) Protection by sulforaphane from type 1 diabetes-induced testicular apoptosis is associated with the up-regulation of Nrf2 expression and function. Toxicology and Applied Pharmacology 279:2, pages 198-210.
Crossref
Francis Berenbaum. (2014) Les brocolis protègent-ils de l’arthrose ?. Revue du Rhumatisme 81:4, pages 278-280.
Crossref
Francis Berenbaum. (2014) Does broccoli protect from osteoarthritis?. Joint Bone Spine 81:4, pages 284-286.
Crossref
Zahra Bahadoran, Parvin Mirmiran & Fereidoun Azizi. (2013) Dietary polyphenols as potential nutraceuticals in management of diabetes: a review. Journal of Diabetes & Metabolic Disorders 12:1.
Crossref
Zahra BahadoranParvin MirmiranFereidoun Azizi. (2013) Potential Efficacy of Broccoli Sprouts as a Unique Supplement for Management of Type 2 Diabetes and Its Complications. Journal of Medicinal Food 16:5, pages 375-382.
Crossref
Aisha Gambo, Nceba Gqaleni & Tesleem Kayode Babalola. (2021) Dietary Diversity and Impact of <i>Moringa oleifera</i> Lam. Leaves Supplemented – Diet on the Nutritional Status and CD4 Cell Counts of Patients Receiving Antiretroviral Therapy in Nigeria: A Double - Blind Randomized Trial. SSRN Electronic Journal.
Crossref

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