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Research Article

Formulation of intranasal mucoadhesive temperature-mediated in situ gel containing ropinirole and evaluation of brain targeting efficiency in rats

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Pages 223-234 | Received 21 Jul 2009, Accepted 27 Sep 2009, Published online: 23 Dec 2009

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Crossref
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Crossref
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Michelly Cristina Galdioli Pellá, Hugo Henrique Carline de Lima, Andrelson Wellington Rinaldi, André Ricardo Fajardo, Ernandes Taveira Tenório-Neto, Marcos Rogério Guilherme, Adley Forti Rubira & Michele Karoline Lima-Tenório. 2019. Functional Chitosan. Functional Chitosan 163 190 .
Michael J. Majcher & Todd Hoare. 2019. Functional Biopolymers. Functional Biopolymers 453 490 .
Nancy Abdel Hamid Abou Youssef, Abeer Ahmed Kassem, Ragwa Mohamed Farid, Fatma Ahmed Ismail, Magda Abd Elsamea EL-Massik & Nabila Ahmed Boraie. (2018) A novel nasal almotriptan loaded solid lipid nanoparticles in mucoadhesive in situ gel formulation for brain targeting: Preparation, characterization and in vivo evaluation. International Journal of Pharmaceutics 548:1, pages 609-624.
Crossref
Shagufta KhanSonali WaradeDilesh J. Singhavi. (2018) Improvement in Ocular Bioavailability and Prolonged Delivery of Tobramycin Sulfate Following Topical Ophthalmic Administration of Drug-Loaded Mucoadhesive Microparticles Incorporated in Thermosensitive In Situ Gel . Journal of Ocular Pharmacology and Therapeutics 34:3, pages 287-297.
Crossref
Blessing Aderibigbe. (2018) In Situ-Based Gels for Nose to Brain Delivery for the Treatment of Neurological Diseases. Pharmaceutics 10:2, pages 40.
Crossref
Dalia M.N. Abouhussein, Abeer Khattab, Noha A. Bayoumi, Ashgan F. Mahmoud & Tamer M. Sakr. (2018) Brain targeted rivastigmine mucoadhesive thermosensitive In situ gel: Optimization, in vitro evaluation, radiolabeling, in vivo pharmacokinetics and biodistribution. Journal of Drug Delivery Science and Technology 43, pages 129-140.
Crossref
Mohammed Hassan Elkomy, Shahira F. El-Menshawe, Adel Ahmed Ali, Abdelkhalik Ali Halawa & Ahmed S. G. Srag El-Din. (2017) Betahistine dihydrochloride transdermal delivery via optimized thermosensitive gels: percutaneous absorption evaluation using rat growth as a biomarker. Drug Delivery and Translational Research 8:1, pages 165-177.
Crossref
Atul P. Sherje & Vaishali Londhe. (2017) Development and Evaluation of pH-Responsive Cyclodextrin-Based in situ Gel of Paliperidone for Intranasal Delivery. AAPS PharmSciTech 19:1, pages 384-394.
Crossref
Paola Mura, Natascia Mennini, Cristina Nativi & Barbara Richichi. (2018) In situ mucoadhesive-thermosensitive liposomal gel as a novel vehicle for nasal extended delivery of opiorphin. European Journal of Pharmaceutics and Biopharmaceutics 122, pages 54-61.
Crossref
Michael J. Majcher & Todd Hoare. 2018. Cellulose-Based Superabsorbent Hydrogels. Cellulose-Based Superabsorbent Hydrogels 1 39 .
Asha Paul, K.M .Fathima & Sreeja C. Nair. (2017) Intra Nasal In situ Gelling System of Lamotrigine Using Ion Activated Mucoadhesive Polymer. The Open Medicinal Chemistry Journal 11:1, pages 222-244.
Crossref
Abdur Rauf Khan, Mengrui Liu, Muhammad Wasim Khan & Guangxi Zhai. (2017) Progress in brain targeting drug delivery system by nasal route. Journal of Controlled Release 268, pages 364-389.
Crossref
Alejandro Sosnik & Katia Seremeta. (2017) Polymeric Hydrogels as Technology Platform for Drug Delivery Applications. Gels 3:3, pages 25.
Crossref
Emine Sekerdag. 2017. Nanotechnology Methods for Neurological Diseases and Brain Tumors. Nanotechnology Methods for Neurological Diseases and Brain Tumors 103 113 .
Li Liu, Qi Gao, Xuemin Lu & Huifang Zhou. (2016) In situ forming hydrogels based on chitosan for drug delivery and tissue regeneration. Asian Journal of Pharmaceutical Sciences 11:6, pages 673-683.
Crossref
Zachary N. Warnken, Hugh D.C. Smyth, Alan B. Watts, Steve Weitman, John G. Kuhn & Robert O. WilliamsIIIIII. (2016) Formulation and device design to increase nose to brain drug delivery. Journal of Drug Delivery Science and Technology 35, pages 213-222.
Crossref
Xingjin Yan, Shouwei Zhao, Wenwen Zhu, Jing Rao, Li Kang, Jiaqiang Xu, Dan Li, Lixia Qin, Lihui Qiu, Gao Li, Jiangeng Huang & Luqin Si. (2016) LC–MS/MS assay of ropinirole in rat biological matrices: elimination of lysoglycerophosphocholines-based matrix effect. Bioanalysis 8:17, pages 1823-1835.
Crossref
Sneha R. Salunke & Sanjay B. Patil. (2016) Ion activated in situ gel of gellan gum containing salbutamol sulphate for nasal administration. International Journal of Biological Macromolecules 87, pages 41-47.
Crossref
Giovanna Rassu, Elena Soddu, Massimo Cossu, Elisabetta Gavini, Paolo Giunchedi & Alessandro Dalpiaz. (2016) Particulate formulations based on chitosan for nose-to-brain delivery of drugs. A review. Journal of Drug Delivery Science and Technology 32, pages 77-87.
Crossref
Christina Karavasili, Nikolaos Bouropoulos, Lamprini Sygellou, Elsa P. Amanatiadou, Ioannis S. Vizirianakis & Dimitrios G. Fatouros. (2016) PLGA/DPPC/trimethylchitosan spray-dried microparticles for the nasal delivery of ropinirole hydrochloride: in vitro , ex vivo and cytocompatibility assessment. Materials Science and Engineering: C 59, pages 1053-1062.
Crossref
Naimat Kalim Bari, Mohammad Fazil, Md Quamrul Hassan, Md Rafi Haider, Bharti Gaba, Jasjeet K. Narang, Sanjula Baboota & Javed Ali. (2015) Brain delivery of buspirone hydrochloride chitosan nanoparticles for the treatment of general anxiety disorder. International Journal of Biological Macromolecules 81, pages 49-59.
Crossref
Weilin Guo, Gao Li, Yanxia Yang, Conglian Yang, Luqin Si & Jiangeng Huang. (2015) LC-MS/MS analysis of pramipexole in mouse plasma and tissues: Elimination of lipid matrix effects using weak cation exchange mode based solid-phase extraction. Journal of Chromatography B 988, pages 157-165.
Crossref
Anjita Singh, Roshni Ubrane, Pallavi Prasad & Suman Ramteke. (2015) Preparation and Characterization of Rizatriptan Benzoate Loaded Solid Lipid Nanoparticles for Brain Targeting. Materials Today: Proceedings 2:9, pages 4521-4543.
Crossref
Mohd Yasir & Udai Vir Singh Sara. (2014) Solid lipid nanoparticles for nose to brain delivery of haloperidol: in vitro drug release and pharmacokinetics evaluation. Acta Pharmaceutica Sinica B 4:6, pages 454-463.
Crossref
Yasmine M. Gabal, Amany O. Kamel, Omaima A. Sammour & Ahmed H. Elshafeey. (2014) Effect of surface charge on the brain delivery of nanostructured lipid carriers in situ gels via the nasal route. International Journal of Pharmaceutics 473:1-2, pages 442-457.
Crossref
Anuja Naik & Hema Nair. (2014) Formulation and Evaluation of Thermosensitive Biogels for Nose to Brain Delivery of Doxepin. BioMed Research International 2014, pages 1-10.
Crossref
Shadabul Haque, Shadab Md, Jasjeet Kaur Sahni, Javed Ali & Sanjula Baboota. (2014) Development and evaluation of brain targeted intranasal alginate nanoparticles for treatment of depression. Journal of Psychiatric Research 48:1, pages 1-12.
Crossref
Matthias van Woensel, Nathalie Wauthoz, Rémi Rosière, Karim Amighi, Véronique Mathieu, Florence Lefranc, Stefaan van Gool & Steven de Vleeschouwer. (2013) Formulations for Intranasal Delivery of Pharmacological Agents to Combat Brain Disease: A New Opportunity to Tackle GBM?. Cancers 5:4, pages 1020-1048.
Crossref
Shadab Md, Rashid A. Khan, Gulam Mustafa, Krishna Chuttani, Sanjula Baboota, Jasjeet K. Sahni & Javed Ali. (2013) Bromocriptine loaded chitosan nanoparticles intended for direct nose to brain delivery: Pharmacodynamic, Pharmacokinetic and Scintigraphy study in mice model. European Journal of Pharmaceutical Sciences 48:3, pages 393-405.
Crossref
John Tsibouklis, Andrew M. Middleton, Nisha Patel & Jonathan Pratten. (2013) Toward mucoadhesive hydrogel formulations for the management of xerostomia: The physicochemical, biological, and pharmacological considerations. Journal of Biomedical Materials Research Part A, pages n/a-n/a.
Crossref
Mohammad Fazil, Shadab Md, Shadabul Haque, Manish Kumar, Sanjula Baboota, Jasjeet kaur Sahni & Javed Ali. (2012) Development and evaluation of rivastigmine loaded chitosan nanoparticles for brain targeting. European Journal of Pharmaceutical Sciences 47:1, pages 6-15.
Crossref
Ana Serralheiro, Gilberto Alves & Amílcar Falcão. (2012) Bioanalysis of small-molecule drugs in nasal and paranasal tissues and secretions: Current status and perspectives. Open Chemistry 10:3, pages 686-702.
Crossref
Shadabul Haque, Shadab Md, Mohammad Fazil, Manish Kumar, Jasjeet Kaur Sahni, Javed Ali & Sanjula Baboota. (2012) Venlafaxine loaded chitosan NPs for brain targeting: Pharmacokinetic and pharmacodynamic evaluation. Carbohydrate Polymers 89:1, pages 72-79.
Crossref
Hamde Nazar, Marta Roldo, Dimitrios G Fatouros, Susanna M van der Merwe & John Tsibouklis. (2012) Hydrogels in mucosal delivery. Therapeutic Delivery 3:4, pages 535-555.
Crossref

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