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Research Article

Formulation and development of release modulated colon targeted system of meloxicam for potential application in the prophylaxis of colorectal cancer

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Pages 281-293 | Received 13 Jul 2010, Accepted 04 Nov 2010, Published online: 07 Dec 2010

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Preksha Vinchhi & Mayur M. Patel. (2021) Triumph against cancer: invading colorectal cancer with nanotechnology. Expert Opinion on Drug Delivery 18:9, pages 1169-1192.
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Zhang Julia Zhang, Tomasz Osmałek & Bozena Michniak-Kohn. (2020) Deformable Liposomal Hydrogel for Dermal and Transdermal Delivery of Meloxicam. International Journal of Nanomedicine 15, pages 9319-9335.
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Gurpreet Kaur Sinhmar, Neel N. Shah, Shruti U. Rawal, Nimitt V. Chokshi, Hiren N. Khatri, Bhoomika M. Patel & Mayur M. Patel. (2018) Surface engineered lipid nanoparticle-mediated site-specific drug delivery system for the treatment of inflammatory bowel disease. Artificial Cells, Nanomedicine, and Biotechnology 46:sup2, pages 565-578.
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Gurpreet Kaur Sinhmar, Neel N. Shah, Nimitt V. Chokshi, Hiren N. Khatri & Mayur M. Patel. (2018) Process, optimization, and characterization of budesonide-loaded nanostructured lipid carriers for the treatment of inflammatory bowel disease. Drug Development and Industrial Pharmacy 44:7, pages 1078-1089.
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Mansi Upadhyay, Sandeep Kumar Reddy Adena, Harsh Vardhan, Sureshwar Pandey & Brahmeshwar Mishra. (2018) Development and optimization of locust bean gum and sodium alginate interpenetrating polymeric network of capecitabine. Drug Development and Industrial Pharmacy 44:3, pages 511-521.
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Tomasz Osmałek, Bartłomiej Milanowski, Anna Froelich, Mirosław Szybowicz, Wojciech Białowąs, Marcin Kapela, Piotr Gadziński & Katarzyna Ancukiewicz. (2017) Design and characteristics of gellan gum beads for modified release of meloxicam. Drug Development and Industrial Pharmacy 43:8, pages 1314-1329.
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Jianmin Chen & Yunhua Gao. (2016) Strategies for meloxicam delivery to and across the skin: a review. Drug Delivery 23:8, pages 3146-3156.
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Mayur M Patel. (2015) Colon: a gateway for chronotherapeutic drug delivery systems. Expert Opinion on Drug Delivery 12:9, pages 1389-1395.
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Ying Huang, Qinghe Yao, Chune Zhu, Xuan Zhang, Lingzhen Qin, Qinruo Wang, Xin Pan & Chuanbin Wu. (2015) Comparison of novel granulated pellet-containing tablets and traditional pellet-containing tablets by artificial neural networks. Pharmaceutical Development and Technology 20:6, pages 670-675.
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Amit Kumar Singh & Kamla Pathak. (2015) Colon specific CODES based Piroxicam tablet for colon targeting: statistical optimization, in vivo roentgenography and stability assessment. Pharmaceutical Development and Technology 20:2, pages 237-245.
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Mayur M Patel. (2014) Getting into the colon: approaches to target colorectal cancer. Expert Opinion on Drug Delivery 11:9, pages 1343-1350.
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Mayur M. Patel & Avani F. Amin. (2013) Development of a novel tablet-in-capsule formulation of mesalamine for inflammatory bowel disease. Pharmaceutical Development and Technology 18:2, pages 390-400.
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Yellela S. R. Krishnaiah & Mansoor A. Khan. (2012) Strategies of targeting oral drug delivery systems to the colon and their potential use for the treatment of colorectal cancer. Pharmaceutical Development and Technology 17:5, pages 521-540.
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Mayur M Patel. (2011) Cutting-edge technologies in colon-targeted drug delivery systems. Expert Opinion on Drug Delivery 8:10, pages 1247-1258.
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Arti A. Bagada, Priya V. Patel & Jalpa S. Paun. 2023. Regenerated Cellulose and Composites. Regenerated Cellulose and Composites 313 346 .
Eva Navarro-Ruíz, Covadonga Álvarez-Álvarez, M Ángeles Peña, Carlos Torrado-Salmerón, Zaid Dahma & Paloma Marina de la Torre-Iglesias. (2022) Multiparticulate Systems of Meloxicam for Colonic Administration in Cancer or Autoimmune Diseases. Pharmaceutics 14:7, pages 1504.
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Prathmesh Kenjale & Varsha Pokharkar. (2022) Risk Assessment and QbD-Based Optimization of Sorafenib Tosylate Colon Targeted Bilayer Tablet: In Vitro Characterization, In Vivo Pharmacokinetic, and In Vivo Roentgenography Studies. AAPS PharmSciTech 23:6.
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Khaled M. Hosny, Hala M. Alkhalidi, Waleed S. Alharbi, Shadab Md, Amal M. Sindi, Sarah A. Ali, Rana B. Bakhaidar, Alshaimaa M. Almehmady, Eman Alfayez & Mallesh Kurakula. (2021) Recent Trends in Assessment of Cellulose Derivatives in Designing Novel and Nanoparticulate-Based Drug Delivery Systems for Improvement of Oral Health. Polymers 14:1, pages 92.
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Yanshan Sheng, Jun Gao, Zheng-Zhi Yin, Jing Kang & Yong Kong. (2021) Dual-drug delivery system based on the hydrogels of alginate and sodium carboxymethyl cellulose for colorectal cancer treatment. Carbohydrate Polymers 269, pages 118325.
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Darya A. Kuznetsova, Leysan A. Vasileva, Gulnara A. Gaynanova, Elmira A. Vasilieva, Oksana A. Lenina, Irek R. Nizameev, Marsil K. Kadirov, Konstantin A. Petrov, Lucia Ya. Zakharova & Oleg G. Sinyashin. (2021) Cationic liposomes mediated transdermal delivery of meloxicam and ketoprofen: Optimization of the composition, in vitro and in vivo assessment of efficiency. International Journal of Pharmaceutics 605, pages 120803.
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Nilesh Rarokar, Ravikumar C, Shailendra Gurav & Pramod Khedekar. (2020) Meloxicam encapsulated nanostructured colloidal self‐assembly for evaluating antitumor and anti‐inflammatory efficacy in 3D printed scaffolds. Journal of Biomedical Materials Research Part A 109:8, pages 1441-1456.
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Nimitt V. Chokshi, Shruti Rawal, Dhruvi Solanki, Saumitra Gajjar, Vivek Bora, Bhoomika M. Patel & Mayur M. Patel. (2021) Fabrication and Characterization of Surface Engineered Rifampicin Loaded Lipid Nanoparticulate Systems for the Potential Treatment of Tuberculosis: An In Vitro and In Vivo Evaluation. Journal of Pharmaceutical Sciences 110:5, pages 2221-2232.
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Annemarie Broesder, Anne-Marijke M.A.C. Kosta, Herman J. Woerdenbag, Duong N. Nguyen, Henderik W. Frijlink & Wouter L.J. Hinrichs. (2020) pH-dependent ileocolonic drug delivery, part II: preclinical evaluation of novel drugs and novel excipients. Drug Discovery Today 25:8, pages 1374-1388.
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Manoj Kumar Sarangi, M.E. Bhanoji Rao, Versha Parcha & Aadesh Upadhyay. (2020) Tailoring of Colon Targeting with Sodium Alginate‐Assam Bora Rice Starch Based Multi Particulate System Containing Naproxen. Starch - Stärke 72:7-8, pages 1900307.
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Julia Zhang, Anna Froelich & Bozena Michniak-Kohn. (2020) Topical Delivery of Meloxicam using Liposome and Microemulsion Formulation Approaches. Pharmaceutics 12:3, pages 282.
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Muhammad Naeem, Uzma Azeem Awan, Fazli Subhan, Jiafu Cao, Shwe Phyu Hlaing, Juho Lee, Eunok Im, Yunjin Jung & Jin-Wook Yoo. (2020) Advances in colon-targeted nano-drug delivery systems: challenges and solutions. Archives of Pharmacal Research 43:1, pages 153-169.
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Muhammad Zaman, Muhammad Hanif & Zaib Ali Shaheryar. (2018) Development of Tizanidine HCl-Meloxicam loaded mucoadhesive buccal films: In-vitro and in-vivo evaluation. PLOS ONE 13:3, pages e0194410.
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Mayur M. Patel. (2017) Formulation and development of di-dependent microparticulate system for colon-specific drug delivery. Drug Delivery and Translational Research 7:2, pages 312-324.
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Mohammad Mahdi Hasani-Sadrabadi, Shahrouz Taranejoo, Erfan Dashtimoghadam, Ghasem Bahlakeh, Fatemeh Sadat Majedi, Jules John VanDersarl, Mohsen Janmaleki, Fatemeh Sharifi, Arnaud Bertsch, Kerry Hourigan, Lobat Tayebi, Philippe Renaud & Karl I. Jacob. (2016) Microfluidic Manipulation of Core/Shell Nanoparticles for Oral Delivery of Chemotherapeutics: A New Treatment Approach for Colorectal Cancer. Advanced Materials 28:21, pages 4134-4141.
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Arvind Gulbake. (2016) Insight to drug delivery aspects for colorectal cancer. World Journal of Gastroenterology 22:2, pages 582.
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Jyoti Wadhwa, Abhay Asthana, Sumeet Gupta, Gyati Shilkari Asthana & Ranjit Singh. (2014) Development and Optimization of Polymeric Self-Emulsifying Nanocapsules for Localized Drug Delivery: Design of Experiment Approach. The Scientific World Journal 2014, pages 1-12.
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Mayur M. Patel & Avani F. Amin. (2011) Process, optimization and characterization of mebeverine hydrochloride loaded guar gum microspheres for irritable bowel syndrome. Carbohydrate Polymers 86:2, pages 536-545.
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Rakesh Kumar Dev, Vikas Bali & Kamla Pathak. (2011) Novel microbially triggered colon specific delivery system of 5-Fluorouracil: Statistical optimization, in vitro, in vivo, cytotoxic and stability assessment. International Journal of Pharmaceutics 411:1-2, pages 142-151.
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