Advanced search
Publication Cover
Autophagy Volume 8, 2012 - Issue 5
Submit an article Journal homepage
6,936
Views
198
CrossRef citations to date
0
Altmetric
Basic Research Paper

Curcumin induces autophagy to protect vascular endothelial cell survival from oxidative stress damage

Jing Han State Key Laboratory of Natural and Biomimetic Drugs; and Department of Pharmacology; School of Basic Medical Sciences; Peking University; Beijing, China
,
Xue-Yang Pan State Key Laboratory of Natural and Biomimetic Drugs; and Department of Pharmacology; School of Basic Medical Sciences; Peking University; Beijing, China
,
Yan Xu State Key Laboratory of Natural and Biomimetic Drugs; and Department of Pharmacology; School of Basic Medical Sciences; Peking University; Beijing, China
,
Yuan Xiao State Key Laboratory of Natural and Biomimetic Drugs; and Department of Pharmacology; School of Basic Medical Sciences; Peking University; Beijing, China
,
Yu An State Key Laboratory of Natural and Biomimetic Drugs; and Department of Pharmacology; School of Basic Medical Sciences; Peking University; Beijing, China
,
Lu Tie State Key Laboratory of Natural and Biomimetic Drugs; and Department of Pharmacology; School of Basic Medical Sciences; Peking University; Beijing, China
,
Yan Pan State Key Laboratory of Natural and Biomimetic Drugs; and Department of Pharmacology; School of Basic Medical Sciences; Peking University; Beijing, China
&
Xue-Jun Li State Key Laboratory of Natural and Biomimetic Drugs; and Department of Pharmacology; School of Basic Medical Sciences; Peking University; Beijing, ChinaCorrespondence[email protected]
 show all
Pages 812-825 | Received 07 Sep 2011, Accepted 24 Jan 2012, Published online: 01 May 2012

Citations (198)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (11)

Jin Zhang, Luxin Li, Jing Yu, Fan Zhang, Jiayi Shi, Meiyun LI, Jianyong Liu, Haitao Li, Jie Gao & Yan Wu. (2023) Autophagy-Modulated Biomaterial: A Robust Weapon for Modulating the Wound Environment to Promote Skin Wound Healing. International Journal of Nanomedicine 18, pages 2567-2588.
Read now
Jing Wang, Yi Zhang, Jin Cao, Yi Wang, Nadia Anwar, Zihan Zhang, Dingmei Zhang, Yaping Ma, Yin Xiao, Lan Xiao & Xin Wang. (2023) The role of autophagy in bone metabolism and clinical significance. Autophagy 19:9, pages 2409-2427.
Read now
Dorien G De Munck, Guido RY De Meyer & Wim Martinet. (2020) Autophagy as an emerging therapeutic target for age-related vascular pathologies. Expert Opinion on Therapeutic Targets 24:2, pages 131-145.
Read now
Manoj Paul, Mahadevappa Hemshekhar, Kempaiah Kemparaju & Kesturu S. Girish. (2019) Aggregation is impaired in starved platelets due to enhanced autophagy and cellular energy depletion. Platelets 30:4, pages 487-497.
Read now
Lu Zhang, PengFei Qiang, JingTing Yu, YiMing Miao, ZhiQiang Chen, Ju Qu, QianBing Zhao, Zhuo Chen, Yachao Liu, Xin Yao, Bin Liu, LiuQing Cui, HongJuan Jing & Gangchun Sun. (2019) Identification of compound CA-5f as a novel late-stage autophagy inhibitor with potent anti-tumor effect against non-small cell lung cancer. Autophagy 15:3, pages 391-406.
Read now
Ming Shen, Yi Jiang, Zhiqiang Guan, Yan Cao, Liechuan Li, Honglin Liu & Shao-chen Sun. (2017) Protective mechanism of FSH against oxidative damage in mouse ovarian granulosa cells by repressing autophagy. Autophagy 13:8, pages 1364-1385.
Read now
Ju-Xian Song, Yue-Ru Sun, Ivana Peluso, Yu Zeng, Xing Yu, Jia-Hong Lu, Zheng Xu, Ming-Zhong Wang, Liang-Feng Liu, Ying-Yu Huang, Lei-Lei Chen, Siva Sundara Kumar Durairajan, Hong-Jie Zhang, Bo Zhou, Hong-Qi Zhang, Aiping Lu, Andrea Ballabio, Diego L. Medina, Zhihong Guo & Min Li. (2016) A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition. Autophagy 12:8, pages 1372-1389.
Read now
Jianbin Zhang, Shukie Ng, Jigang Wang, Jing Zhou, Shi-Hao Tan, Naidi Yang, Qingsong Lin, Dajing Xia & Han-Ming Shen. (2015) Histone deacetylase inhibitors induce autophagy through FOXO1-dependent pathways. Autophagy 11:4, pages 629-642.
Read now
Khaled Radad, Rudolf Moldzio, Mubarak Al-Shraim, Barbara Kranner, Christopher Krewenka & Wolf-Dieter Rausch. (2015) Recent advances in autophagy-based neuroprotection. Expert Review of Neurotherapeutics 15:2, pages 195-205.
Read now
Ming-liang Chen, Long Yi, Xin Jin, Xin-yu Liang, Yong Zhou, Ting Zhang, Qi Xie, Xi Zhou, Hui Chang, Yu-jie Fu, Jun-dong Zhu, Qian-yong Zhang & Man-tian Mi. (2013) Resveratrol attenuates vascular endothelial inflammation by inducing autophagy through the cAMP signaling pathway. Autophagy 9:12, pages 2033-2045.
Read now
D. Neves. (2013) Advanced glycation end-products: a common pathway in diabetes and age-related erectile dysfunction. Free Radical Research 47:sup1, pages 49-69.
Read now

Articles from other publishers (187)

Gloria Lazzeri, Francesca Biagioni, Michela Ferrucci, Stefano Puglisi-Allegra, Paola Lenzi, Carla Letizia Busceti, Francesco Giannessi & Francesco Fornai. (2023) The Relevance of Autophagy within Inner Ear in Baseline Conditions and Tinnitus-Related Syndromes. International Journal of Molecular Sciences 24:23, pages 16664.
Crossref
Muna Barakat, Nabeel Kashan Syed, Eliza Hasen, Shaymaa B. Abdulrazzaq, Samar Thiab, Mohammad A.A. Al-Najjar, Amin Omar, Tanzima Tarannum Lucy, A.N.M. Mamun-Or-Rashid, Masayuki Yagi & Yoshikazu Yonei. (2023) The effect of natural products on inflammatory cytokines production and secretion. Phytomedicine Plus 3:4, pages 100488.
Crossref
Fei Tang, Dong Liu, Li Zhang, Li-Yue Xu, Jing-Nan Zhang, Xiao-Lan Zhao, Hui Ao & Cheng Peng. (2023) Targeting endothelial cells with golden spice curcumin: A promising therapy for cardiometabolic multimorbidity. Pharmacological Research 197, pages 106953.
Crossref
Jialing Shen, Cheng Zhang, Yong Liu, Ming Zhao, Qianqian Wang, Pengyun Li, Runyu Liu, Vincent Kam Wai Wong, Chunxiang Zhang & Xiaolei Sun. (2023) L-type calcium ion channel-mediated activation of autophagy in vascular smooth muscle cells via thonningianin A (TA) alleviates vascular calcification in type 2 diabetes mellitus. European Journal of Pharmacology 959, pages 176084.
Crossref
Jing-Juan Yang, Sheng-Lan Zhao, Xi Zhang, Ya-Ge Ma & Jian-Guo Jiang. (2023) Polygonatum kingianum saponins delay cellular senescence through SASP down-regulation and prolong the healthy lifespan of Caenorhabditis elegans by activating sir-2.1/autophagy. Industrial Crops and Products 201, pages 116903.
Crossref
Tammy R. Hoffman, Sarah A. Emsley, Jenna C. Douglas, Kaela R. Reed, Abigail R. Esquivel, Marc J. Koyack, Brie E. Paddock & Patrick Videau. (2023) Assessing Curcumin Uptake and Clearance and Their Influence on Superoxide Dismutase Activity in Drosophila melanogaster. BioTech 12:3, pages 58.
Crossref
Magdalena Bielawska, Marta Warszyńska, Monika Stefańska & Przemysław Błyszczuk. (2023) Autophagy in Heart Failure: Insights into Mechanisms and Therapeutic Implications. Journal of Cardiovascular Development and Disease 10:8, pages 352.
Crossref
Chenchen Zhao, Bing Wu, Jinxia Li, Qianming Jiang, Juan J. Loor, Menglin Liu, Linfang Chen, Yiwei Zhu, Wenwen Gao, Xiliang Du, Yuxiang Song, Guowen Liu, Lin Lei & Xinwei Li. (2023) AdipoRon alleviates fatty acid–induced lipid accumulation and mitochondrial dysfunction in bovine hepatocytes by promoting autophagy. Journal of Dairy Science 106:8, pages 5763-5774.
Crossref
SeungHoon Lee, Haeyun Jeong, Hayeon Wi, Jin-Gu No, Whi-Cheul Lee, Seokho Kim, Hyeon Yang, Sung June Byun, Sejin Park & Jong Gug Kim. (2023) Autophagic activation in porcine oocytes is independent of meiotic progression. Zygote, pages 1-6.
Crossref
Dehua Liao, Danggang Shangguan, Yi Wu, Yun Chen, Ni Liu, Jingyi Tang, Dunwu Yao & Yingrui Shi. (2023) Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways. Psychopharmacology 240:5, pages 1179-1190.
Crossref
Jiani Yang, Chao Wang, Yue Zhang, Shanshan Cheng, Meixuan Wu, Sijia Gu, Shilin Xu, Yongsong Wu & Yu Wang. (2023) A novel autophagy-related gene signature associated with prognosis and immune microenvironment in ovarian cancer. Journal of Ovarian Research 16:1.
Crossref
Bing Jiang, Xuan Zhou, Tao Yang, Linlin Wang, Longfei Feng, Zheng Wang, Jin Xu, Weiyao Jing, Tao Wang, Haixiang Su, GuoWei Yang & Zheng Zhang. (2023) The role of autophagy in cardiovascular disease: Cross-interference of signaling pathways and underlying therapeutic targets. Frontiers in Cardiovascular Medicine 10.
Crossref
Fengjuan Jiao, Bojie Zhou & Lingyan Meng. (2022) The regulatory mechanism and therapeutic potential of transcription factor EB in neurodegenerative diseases . CNS Neuroscience & Therapeutics 29:1, pages 37-59.
Crossref
Renxu Chang, Xudong Sun, Hongdou Jia, Qiushi Xu, Zhihao Dong, Yan Tang, Shengbin Luo, Qianming Jiang, Juan J. Loor & Chuang Xu. (2022) Inhibiting nuclear factor erythroid 2 related factor 2-mediated autophagy in bovine mammary epithelial cells induces oxidative stress in response to exogenous fatty acids. Journal of Animal Science and Biotechnology 13:1.
Crossref
Yuexuan Wang, Suifeng Xu, Chengzong Han, Youhua Huang, Jingguang Wei, Shina Wei & Qiwei Qin. (2022) Modulatory effects of curcumin on Singapore grouper iridovirus infection-associated apoptosis and autophagy in vitro. Fish & Shellfish Immunology 131, pages 84-94.
Crossref
Taegum Lee, Yeonji Oh, Mi Kyoung Kim & Youhoon Chong. (2022) Green Tea Catechol (−)-Epigallocatechin Gallate (EGCG) Conjugated with Phenylalanine Shows Enhanced Autophagy Stimulating Activity in Human Aortic Endothelial Cells. Planta Medica.
Crossref
Pengyu Tao, Wenxin Xu, Simeng Gu, Haiyan Shi, Qian Wang & Yuzhen Xu. (2022) Traditional Chinese medicine promotes the control and treatment of dementia. Frontiers in Pharmacology 13.
Crossref
Cheng Zhao, Zi-yi Yang, Jian Zhang, Ou Li, Shi-lei Liu, Chen Cai, Yi-jun Shu, Li-jia Pan, Wei Gong & Ping Dong. (2022) Inhibition of XPO1 with KPT-330 induces autophagy-dependent apoptosis in gallbladder cancer by activating the p53/mTOR pathway. Journal of Translational Medicine 20:1.
Crossref
Pengfei PangShirong Zhang. (2022) Dasatinib enhances curcumin-induced cytotoxicity, apoptosis and protective autophagy in human schwannoma cells HEI-193: The role of Akt/mTOR/p70S6K signalling pathway. Acta Pharmaceutica 72:3, pages 403-414.
Crossref
Guang Lu, Yu Wang, Yin Shi, Zhe Zhang, Canhua Huang, Weifeng He, Chuang Wang & Han‐Ming Shen. (2022) Autophagy in health and disease: From molecular mechanisms to therapeutic target. MedComm 3:3.
Crossref
Douglas B. Kell & Etheresia Pretorius. (2022) The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and therapeutic implications. Biochemical Journal 479:16, pages 1653-1708.
Crossref
Ming Zhang, Peina Ji, Zhongzhen Li, Zaiqiao Sun, Ngoc Tuan Tran & Shengkang Li. (2022) Catalase regulates the homeostasis of hemolymph microbiota and autophagy of the hemocytes in mud crab (Scylla paramamosain). Aquaculture Reports 25, pages 101237.
Crossref
Priyanka Joshi, Akansha Bisht, Sushil Joshi, Deepak Semwal, Neelesh Kumar Nema, Jaya Dwivedi & Swapnil Sharma. (2022) Ameliorating potential of curcumin and its analogue in central nervous system disorders and related conditions: A review of molecular pathways. Phytotherapy Research 36:8, pages 3143-3180.
Crossref
Qi-Hui Jin, Xu-Jun Hu & Hai-Yan Zhao. (2022) Curcumin activates autophagy and attenuates high glucose‑induced apoptosis in HUVECs through the ROS/NF‑κB signaling pathway. Experimental and Therapeutic Medicine 24:3.
Crossref
Lei He, Cheng-Lin Zhang, Qinghua Chen, Li Wang & Yu Huang. (2022) Endothelial shear stress signal transduction and atherogenesis: From mechanisms to therapeutics. Pharmacology & Therapeutics 235, pages 108152.
Crossref
Xuesong Li, Ruigong Zhu, Hong Jiang, Quanwen Yin, Jiaming Gu, Jiajing Chen, Xian Ji, Xuan Wu, Haiping Fu, Hui Wang, Xin Tang, Yuanqing Gao, Bingjian Wang, Yong Ji & Hongshan Chen. (2022) Autophagy enhanced by curcumin ameliorates inflammation in atherogenesis via the TFEB–P300–BRD4 axis. Acta Pharmaceutica Sinica B 12:5, pages 2280-2299.
Crossref
Pengyu Tao, Jing Ji, Simeng Gu, Qian Wang & Yuzhen Xu. (2022) Progress in the Mechanism of Autophagy and Traditional Chinese Medicine Herb Involved in Dementia. Frontiers in Pharmacology 12.
Crossref
Fiona Frederike Cox, Angelina Misiou, Annika Vierkant, Niloofar Ale-Agha, Maria Grandoch, Judith Haendeler & Joachim Altschmied. (2022) Protective Effects of Curcumin in Cardiovascular Diseases—Impact on Oxidative Stress and Mitochondria. Cells 11:3, pages 342.
Crossref
Fang Cui, Min Shi, Hao-Fei Hu, Yan-Ming Tian, Chen-Ming Zhou, Hai-Chao Mi, Shuo Gu, Zan Guo, Xiang-Jian Zhang & Yi Zhang. (2022) Adenosine mono-phosphate-activated protein kinase-mammalian target of rapamycin signaling participates in the protective effect of chronic intermittent hypobaric hypoxia on vascular endothelium of metabolic syndrome rats. Chinese Journal of Physiology 65:2, pages 53.
Crossref
Y. Karamalakova, E. Georgieva, V. Ivanov, K Parlapanska & G. Nikolova. (2022) ANTIOXIDANTLY-MODULATIVE, CHEMOPREVENTIVE AND ANTI-SARS-COVID 19 ACTION OF MEDICINAL PLANTS. Trakia Journal of Sciences 20:4, pages 267-282.
Crossref
Shan Liang, Yun-Shan Wu, Dong-Yi Li, Ji-Xin Tang & Hua-Feng Liu. (2022) Autophagy and Renal Fibrosis. Aging and disease 13:3, pages 712.
Crossref
Parinaz Zivarpour, Željko Reiner, Jamal Hallajzadeh, Liaosadat Mirsafaei & Zatollah Asemi. (2020) The effect of nutraceuticals on multiple signaling pathways in cardiac fibrosis injury and repair. Heart Failure Reviews 27:1, pages 321-336.
Crossref
Jiayin Lu, Jiaqiang Huang, Shisu Zhao, Wenjiao Xu, Yaoxing Chen, Yuanyuan Li, Zixu Wang, Yanjun Dong, Renrong You, Jing Cao & Yulan Dong. (2021) FOXO1 Is a Critical Switch Molecule for Autophagy and Apoptosis of Sow Endometrial Epithelial Cells Caused by Oxidative Stress. Oxidative Medicine and Cellular Longevity 2021, pages 1-24.
Crossref
Xudong Sun, Renxu Chang, Yan Tang, Shengbin Luo, Chunhui Jiang, Hongdou Jia, Qiushi Xu, Zhihao Dong, Yusheng Liang, Juan J. Loor & Chuang Xu. (2021) Transcription factor EB (TFEB)-mediated autophagy protects bovine mammary epithelial cells against H2O2-induced oxidative damage in vitro. Journal of Animal Science and Biotechnology 12:1.
Crossref
Shujuan Zhou, Lan Sun, Shanhu Qian, Yongyong Ma, Ruye Ma, Yuqing Dong, Yifen Shi, Songfu Jiang, Haige Ye, Zhijian Shen, Shenghui Zhang, Jianping Shen, Kang Yu & Siqian Wang. (2021) Iron overload adversely effects bone marrow haematogenesis via SIRT-SOD2-mROS in a process ameliorated by curcumin. Cellular & Molecular Biology Letters 26:1.
Crossref
Jiaqiang Deng, Ping Ouyang, Weiyao Li, Lijun Zhong, Congwei Gu, Liuhong Shen, Suizhong Cao, Lizi Yin, Zhihua Ren, Zhicai Zuo, Junliang Deng, Qigui Yan & Shumin Yu. (2021) Curcumin Alleviates the Senescence of Canine Bone Marrow Mesenchymal Stem Cells during In Vitro Expansion by Activating the Autophagy Pathway. International Journal of Molecular Sciences 22:21, pages 11356.
Crossref
Arun Upadhyay. (2021) Natural compounds in the regulation of proteostatic pathways: An invincible artillery against stress, ageing, and diseases. Acta Pharmaceutica Sinica B 11:10, pages 2995-3014.
Crossref
Wamidh H. Talib, Ahmad Riyad Alsayed, Muna Barakat, May Ibrahim Abu-Taha & Asma Ismail Mahmod. (2021) Targeting Drug Chemo-Resistance in Cancer Using Natural Products. Biomedicines 9:10, pages 1353.
Crossref
Hui Ding, Hengjuan Guo & Jie Cao. (2021) The importance of autophagy regulation in obstructive sleep apnea. Sleep and Breathing 25:3, pages 1211-1218.
Crossref
Gailan WangYing ZhuKaiting LiBo LiaoFang WangLan ShaoLiyi HuangDingqun Bai. (2021) Curcumin-mediated Photodynamic Therapy Inhibits the Phenotypic Transformation, Migration, and Foaming of Oxidized Low-density Lipoprotein-treated Vascular Smooth Muscle Cells by Promoting Autophagy. Journal of Cardiovascular Pharmacology 78:2, pages 308-318.
Crossref
Shuhan Bu & Krishna K. Singh. (2021) Epigenetic Regulation of Autophagy in Cardiovascular Pathobiology. International Journal of Molecular Sciences 22:12, pages 6544.
Crossref
Rengasamy Balakrishnan, Shofiul Azam, Duk-Yeon Cho, In Su-Kim & Dong-Kug Choi. (2021) Natural Phytochemicals as Novel Therapeutic Strategies to Prevent and Treat Parkinson’s Disease: Current Knowledge and Future Perspectives. Oxidative Medicine and Cellular Longevity 2021, pages 1-32.
Crossref
MD Khurshidul ZahidHazera Binte SufianMahua ChoudhuryMasao Yamasaki, Ahmed Al-Harrasi, Naima Moustaid-MoussaShaikh Mizanoor Rahman. (2021) Role of macrophage autophagy in atherosclerosis: modulation by bioactive compounds. Biochemical Journal 478:7, pages 1359-1375.
Crossref
Ali Mohammad Pourbagher-Shahri, Tahereh Farkhondeh, Milad Ashrafizadeh, Marjan Talebi & Saeed Samargahndian. (2021) Curcumin and cardiovascular diseases: Focus on cellular targets and cascades. Biomedicine & Pharmacotherapy 136, pages 111214.
Crossref
Jiaxing Sun, Shi Tai, Liang Tang, Hui Yang, Mingxian Chen, Yichao Xiao, Xuping Li, Zhaowei Zhu & Shenghua Zhou. (2021) Acetylation Modification During Autophagy and Vascular Aging. Frontiers in Physiology 12.
Crossref
Ju-Xian Song, Jia Liu, Yimin Jiang, Zi-Ying Wang & Min Li. (2021) Transcription factor EB: an emerging drug target for neurodegenerative disorders. Drug Discovery Today 26:1, pages 164-172.
Crossref
Milad Ashrafizadeh, Shima Tavakol, Reza Mohammadinejad, Zahra Ahmadi, Habib Yaribeygi, Tannaz Jamialahmadi, Thomas P. Johnston & Amirhossein Sahebkar. 2021. Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health. Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health 137 160 .
Karima Ait-Aissa, Quynh My Nguyen, Mohanad Gabani, Adam Kassan, Santosh Kumar, Soo-Kyoung Choi, Alexis A. Gonzalez, Tahsin Khataei, Amal M. Sahyoun, Cheng Chen & Modar Kassan. (2020) MicroRNAs and obesity-induced endothelial dysfunction: key paradigms in molecular therapy. Cardiovascular Diabetology 19:1.
Crossref
Haoyi Zheng, Haitao Feng, Wenzhong Zhang, Yantao Han & Wenwen Zhao. (2020) Targeting autophagy by natural product Ursolic acid for prevention and treatment of osteoporosis. Toxicology and Applied Pharmacology 409, pages 115271.
Crossref
Abigail R. Esquivel, Jenna C. Douglas, Rachel M. Loughran, Thomas E. Rezendes, Kaela R. Reed, Tobias H. L. Cains, Sarah A. Emsley, William A. Paddock, Patrick Videau, Marc J. Koyack & Brie E. Paddock. (2020) Assessing the influence of curcumin in sex-specific oxidative stress, survival and behavior in Drosophila melanogaster . Journal of Experimental Biology 223:22.
Crossref
Mengmeng You, Zhuoning Miao, Jing Tian & Fuliang Hu. (2019) Trans-10-hydroxy-2-decenoic acid protects against LPS-induced neuroinflammation through FOXO1-mediated activation of autophagy. European Journal of Nutrition 59:7, pages 2875-2892.
Crossref
Nimmy Varghese, Selina Werner, Amandine Grimm & Anne Eckert. (2020) Dietary Mitophagy Enhancer: A Strategy for Healthy Brain Aging?. Antioxidants 9:10, pages 932.
Crossref
Jitendra Kumar, Chandana Haldar & Rakesh Verma. (2019) Fluoride Compromises Testicular Redox Sensor, Gap Junction Protein, and Metabolic Status: Amelioration by Melatonin. Biological Trace Element Research 196:2, pages 552-564.
Crossref
Zhi-Gang Mei, Ya-Guang Huang, Zhi-Tao Feng, Ya-Nan Luo, Song-Bai Yang, Li-Peng Du, Kang Jiang, Xiao-Lu Liu, Xian-Yun Fu, Yi-Hui Deng & Hua-Jun Zhou. (2020) Electroacupuncture ameliorates cerebral ischemia/reperfusion injury by suppressing autophagy via the SIRT1-FOXO1 signaling pathway. Aging 12:13, pages 13187-13205.
Crossref
Sergio Davinelli, Diego De Stefani, Immaculata De Vivo & Giovanni Scapagnini. (2020) Polyphenols as Caloric Restriction Mimetics Regulating Mitochondrial Biogenesis and Mitophagy. Trends in Endocrinology & Metabolism 31:7, pages 536-550.
Crossref
Ahmad Tamaddoni, Elahe Mohammadi, Fatemeh Sedaghat, Durdi Qujeq & Atefeh As’Habi. (2020) The anticancer effects of curcumin via targeting the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway. Pharmacological Research 156, pages 104798.
Crossref
Minghui Ou, Xia Li, Shichao Cui, Shibo Zhao & Jie Tu. (2020) Emerging roles of let‑7d in attenuating pulmonary arterial hypertension via suppression of pulmonary artery endothelial cell autophagy and endothelin synthesis through ATG16L1 downregulation. International Journal of Molecular Medicine.
Crossref
Hossein Kargar Jahromi, Ali Farzin, Elham Hasanzadeh, Somayeh Ebrahimi Barough, Narges Mahmoodi, Mohammad Reza H. Najafabadi, Morteza Sagharjoghi Farahani, Korosh Mansoori, Sadegh Shirian & Jafar Ai. (2020) Enhanced sciatic nerve regeneration by poly-L-lactic acid/multi-wall carbon nanotube neural guidance conduit containing Schwann cells and curcumin encapsulated chitosan nanoparticles in rat. Materials Science and Engineering: C 109, pages 110564.
Crossref
Kristen L. Nowak & Charles L. Edelstein. (2020) Apoptosis and autophagy in polycystic kidney disease (PKD). Cellular Signalling 68, pages 109518.
Crossref
Katrin Spengler, Nderim Kryeziu, Silke Große, Alexander S. Mosig & Regine Heller. (2020) VEGF Triggers Transient Induction of Autophagy in Endothelial Cells via AMPKα1. Cells 9:3, pages 687.
Crossref
Li-Tao Yi, Shu-Qi Dong, Shuang-Shuang Wang, Min Chen, Cheng-Fu Li, Di Geng, Ji-Xiao Zhu, Qing Liu & Jie Cheng. (2020) Curcumin attenuates cognitive impairment by enhancing autophagy in chemotherapy. Neurobiology of Disease 136, pages 104715.
Crossref
Yasmina M. Abd El-Hakim, Walaa El-Houseiny, Abd Elhakeem EL-Murr, Lamiaa L.M. Ebraheim, Amr A. Moustafa & Amany Abdel Rahman Mohamed. (2020) Melamine and curcumin enriched diets modulate the haemato-immune response, growth performance, oxidative stress, disease resistance, and cytokine production in oreochromis niloticus. Aquatic Toxicology 220, pages 105406.
Crossref
Qian Zhao, Cheng Peng, Chuan Zheng, Xiang-Hong He, Wei Huang & Bo Han. (2020) Recent Advances in Characterizing Natural Products that Regulate Autophagy. Anti-Cancer Agents in Medicinal Chemistry 19:18, pages 2177-2196.
Crossref
Guangyao Shi, Dinghui Liu, Bin Zhou, Yong Liu, Baoshun Hao, Shujie Yu, Lin Wu, Min Wang, Zhiming Song, Chaodong Wu, Jieming Zhu & Xiaoxian Qian. (2020) Ginsenoside Rb1 Alleviates Oxidative Low-Density Lipoprotein–Induced Vascular Endothelium Senescence via the SIRT1/Beclin-1/Autophagy Axis. Journal of Cardiovascular Pharmacology 75:2, pages 155-167.
Crossref
Ana Sanches-Silva, Lara Testai, Seyed Fazel Nabavi, Maurizio Battino, Kasi Pandima Devi, Silvia Tejada, Antoni Sureda, Suowen Xu, Bahman Yousefi, Maryam Majidinia, Gian Luigi Russo, Thomas Efferth, Seyed Mohammad Nabavi & Mohammad Hossein Farzaei. (2020) Therapeutic potential of polyphenols in cardiovascular diseases: Regulation of mTOR signaling pathway. Pharmacological Research 152, pages 104626.
Crossref
Dan-Yang Zhao, Dong-Dong Yu, Li Ren & Guo-Rong Bi. (2020) Ligustilide protects PC12 cells from oxygen-glucose deprivation/reoxygenation-induced apoptosis via the LKB1-AMPK-mTOR signaling pathway. Neural Regeneration Research 15:3, pages 473.
Crossref
Dianshan Ke, Yu Wang, Yunlong Yu, Yongxuan Wang, Wang Zheng, Xiaomin Fu, Junyong Han, Guoyou Zhang & Jie Xu. (2020) Curcumin-activated autophagy plays a negative role in its anti-osteoclastogenic effect. Molecular and Cellular Endocrinology 500, pages 110637.
Crossref
Rosa Anna Milella, Marica Gasparro, Fiammetta Alagna, Maria Francesca Cardone, Silvia Rotunno, Concetta Tiziana Ammollo, Fabrizio Semeraro, Apollonia Tullo, Flaviana Marzano, Domenico Catalano, Donato Antonacci, Mario Colucci & Domenica D'Elia. (2020) Gene expression signature induced by grape intake in healthy subjects reveals wide-spread beneficial effects on peripheral blood mononuclear cells. Journal of Functional Foods 64, pages 103705.
Crossref
Xiaolei Sun, Anguo Wu, Betty Yuen Kwan Law, Chaolin Liu, Wu Zeng, Alena Cong Ling Qiu, Yu Han, Yanzheng He & Vincent Kam Wai Wong. (2020) The active components derived from Penthorum chinense Pursh protect against oxidative-stress-induced vascular injury via autophagy induction. Free Radical Biology and Medicine 146, pages 160-180.
Crossref
Simeng Gu & Xuejun Li. 2020. Autophagy: Biology and Diseases. Autophagy: Biology and Diseases 731 736 .
Maria Mrakovcic & Leopold F. Fröhlich. (2019) Molecular Determinants of Cancer Therapy Resistance to HDAC Inhibitor-Induced Autophagy. Cancers 12:1, pages 109.
Crossref
Bahareh Kardideh, Zahra Samimi, Fatemeh Norooznezhad, Sarah Kiani & Kamran Mansouri. (2019) Autophagy, cancer and angiogenesis: where is the link?. Cell & Bioscience 9:1.
Crossref
Yu Wan, Yingxia Liang, Feng Liang, Nolan Shen, Kenneth Shinozuka, Jin-Tai Yu, Chongzhao Ran, Qimin Quan, Rudolph E. Tanzi & Can Zhang. (2019) A Curcumin Analog Reduces Levels of the Alzheimer’s Disease-Associated Amyloid-β Protein by Modulating AβPP Processing and Autophagy. Journal of Alzheimer's Disease 72:3, pages 761-771.
Crossref
Havovi ChichgerSharon RoundsElizabeth O. Harrington. (2019) Endosomes and Autophagy: Regulators of Pulmonary Endothelial Cell Homeostasis in Health and Disease. Antioxidants & Redox Signaling 31:13, pages 994-1008.
Crossref
Feng Tang & Chunhua Ling. (2019) Curcumin ameliorates chronic obstructive pulmonary disease by modulating autophagy and endoplasmic reticulum stress through regulation of SIRT1 in a rat model. Journal of International Medical Research 47:10, pages 4764-4774.
Crossref
Yangwu Chen, Yubin Xie, Mengfei Liu, Jiajie Hu, Chenqi Tang, Jiayun Huang, Tian Qin, Xiao Chen, Weishan Chen, Weiliang Shen & Zi Yin. (2019) Controlled-release curcumin attenuates progression of tendon ectopic calcification by regulating the differentiation of tendon stem/progenitor cells. Materials Science and Engineering: C 103, pages 109711.
Crossref
Sánchez-Álvarez, Strippoli, Donadelli, Bazhin & Cordani. (2019) Sestrins as a Therapeutic Bridge between ROS and Autophagy in Cancer. Cancers 11:10, pages 1415.
Crossref
Zhiyong Cheng. (2019) The FoxO–Autophagy Axis in Health and Disease. Trends in Endocrinology & Metabolism 30:9, pages 658-671.
Crossref
Yefan Wang, Shengjun Fan, Xin Li, Yilixiati Xiaokaiti, Yan Pan, Lu Tie & Xuejun Li. (2019) The novel small molecular BH3 mimetics SM3 and its regulation of cell apoptosis and autophagy. Biochemical and Biophysical Research Communications 517:1, pages 15-22.
Crossref
Jimei Duan, Jiuju Du, Rongrong Jin, Wencheng Zhu, Li Liu, Li Yang, Mengye Li, Qiyong Gong, Bin Song, James M Anderson & Hua Ai. (2019) Iron oxide nanoparticles promote vascular endothelial cells survival from oxidative stress by enhancement of autophagy. Regenerative Biomaterials 6:4, pages 221-229.
Crossref
Luigi Minafra, Nunziatina Porcino, Valentina Bravatà, Daniela Gaglio, Marcella Bonanomi, Erika Amore, Francesco Paolo Cammarata, Giorgio Russo, Carmelo Militello, Gaetano Savoca, Margherita Baglio, Boris Abbate, Giuseppina Iacoviello, Giovanna Evangelista, Maria Carla Gilardi, Maria Luisa Bondì & Giusi Irma Forte. (2019) Radiosensitizing effect of curcumin-loaded lipid nanoparticles in breast cancer cells. Scientific Reports 9:1.
Crossref
Fiona Limanaqi, Francesca Biagioni, Carla Letizia Busceti, Larisa Ryskalin, Maico Polzella, Alessandro Frati & Francesco Fornai. (2019) Phytochemicals Bridging Autophagy Induction and Alpha-Synuclein Degradation in Parkinsonism. International Journal of Molecular Sciences 20:13, pages 3274.
Crossref
Abolfazl Shakeri, Arrigo F. G. Cicero, Yunes Panahi, Mohammad Mohajeri & Amirhossein Sahebkar. (2018) Curcumin: A naturally occurring autophagy modulator. Journal of Cellular Physiology 234:5, pages 5643-5654.
Crossref
Lynn M. Martin, Nallathambi Jeyabalan, Ratnakar Tripathi, Trailokyanath Panigrahi, Philip J. Johnson, Arkasubhra Ghosh & Rajiv R. Mohan. (2019) Autophagy in corneal health and disease: A concise review. The Ocular Surface 17:2, pages 186-197.
Crossref
Jinfeng Xie, Jiling Liang & Ning Chen. (2019) Autophagy-associated signal pathways of functional foods for chronic diseases. Food Science and Human Wellness 8:1, pages 25-33.
Crossref
Yun Luo, Shan Lu, Qidi Ai, Ping Zhou, Meng Qin, Guibo Sun & Xiaobo Sun. (2019) SIRT1/AMPK and Akt/eNOS signaling pathways are involved in endothelial protection of total aralosides of Aralia elata ( Miq ) S eem against high‐fat diet‐induced atherosclerosis in ApoE −/− mice . Phytotherapy Research 33:3, pages 768-778.
Crossref
Keshuai He, Haoliang Sun, Junjie Zhang, Rui Zheng, Jiaxi Gu, Ming Luo & Yongfeng Shao. (2019) Rab7‑mediated autophagy regulates phenotypic transformation and behavior of smooth muscle cells via the Ras/Raf/MEK/ERK signaling pathway in human aortic dissection. Molecular Medicine Reports.
Crossref
Zhen Luo, Xue Xu, Takami Sho, Jing Zhang, Weina Xu, Jianbo Yao & Jianxiong Xu. (2019) ROS-induced autophagy regulates porcine trophectoderm cell apoptosis, proliferation, and differentiation. American Journal of Physiology-Cell Physiology 316:2, pages C198-C209.
Crossref
Cindy Valentine, Kohta Ohnishi, Kazuhiro Irie & Akira Murakami. (2019) Curcumin may induce lipolysis via proteo-stress in Huh7 human hepatoma cells. Journal of Clinical Biochemistry and Nutrition 65:2, pages 91-98.
Crossref
Xin Jiang, Xiaoli Niu, Qingjun Guo, Yanhong Dong, Jing Xu, Nan Yin, Qianqian Qi, Yanqiu Jia, Liwei Gao, Qihui He & Peiyuan Lv. (2019) FoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia. Behavioural Brain Research 356, pages 98-106.
Crossref
Mehdi Hassanpour, Aysa Rezabakhsh, Masoud Pezeshkian, Reza Rahbarghazi & Mohammad Nouri. (2018) Distinct role of autophagy on angiogenesis: highlights on the effect of autophagy in endothelial lineage and progenitor cells. Stem Cell Research & Therapy 9:1.
Crossref
Cong Lan, Xinjian Chen, Yuxun Zhang, Wei Wang, Wei Eric Wang, Yukai Liu, Yue Cai, Hongmei Ren, Shuo Zheng, Lin Zhou & Chunyu Zeng. (2018) Curcumin prevents strokes in stroke-prone spontaneously hypertensive rats by improving vascular endothelial function. BMC Cardiovascular Disorders 18:1.
Crossref
Linghuan Li, Jiameng Qi & Hanbing Li. (2018) Natural Products Modulating Autophagy Pathway Against the Pathogenesis of Diabetes Mellitus. Current Drug Targets 20:1, pages 96-110.
Crossref
Jing-Bo Hu, Di Liu, Jing Qi, Kong-jun Lu, Fei-yang Jin, Xiao-Ying Ying, Jian You & Yong-Zhong Du. (2018) An E-selectin targeting and MMP-2-responsive dextran–curcumin polymeric prodrug for targeted therapy of acute kidney injury. Biomaterials Science 6:12, pages 3397-3409.
Crossref
Pei Zhang, Jie Zhang, Yexin Zhang, Shuai Wang, Shuchao Pang & Bo Yan. (2018) Functional variants of the ATG 7 gene promoter in acute myocardial infarction . Molecular Genetics & Genomic Medicine 6:6, pages 1209-1219.
Crossref
Hanxiao Ou, Chuhao Liu, Wenjie Feng, Xinwen Xiao, Shengsong Tang & Zhongcheng Mo. (2018) Role of AMPK in atherosclerosis via autophagy regulation. Science China Life Sciences 61:10, pages 1212-1221.
Crossref
Richard Greil, Sigrun Greil-Ressler, Lukas Weiss, Charlotte Schönlieb, Teresa Magnes, Bianca Radl, Gordon T. Bolger, Brigitta Vcelar & Peter P. Sordillo. (2018) A phase 1 dose-escalation study on the safety, tolerability and activity of liposomal curcumin (Lipocurc™) in patients with locally advanced or metastatic cancer. Cancer Chemotherapy and Pharmacology 82:4, pages 695-706.
Crossref
Ricky H. Bhogal, Christopher J. Weston, Susanne Velduis, Henri G. D. Leuvenink, Gary M. Reynolds, Scott Davies, Luu Nyguet‐Thin, Mohammed Alfaifi, Emma L. Shepard, Yuri Boteon, Lorraine Wallace, Ye H. Oo, David H. Adams, Darius F. Mirza, Hynek Mergental, Gillian Muirhead, Barnaby T. F. Stephenson & Simon C. Afford. (2018) The Reactive Oxygen Species–Mitophagy Signaling Pathway Regulates Liver Endothelial Cell Survival During Ischemia/Reperfusion Injury. Liver Transplantation 24:10, pages 1437-1452.
Crossref
Yoona Kim & Peter Clifton. (2018) Curcumin, Cardiometabolic Health and Dementia. International Journal of Environmental Research and Public Health 15:10, pages 2093.
Crossref
Jing-Bo Hu, Shu-Juan Li, Xu-Qi Kang, Jing Qi, Jia-Hui Wu, Xiao-Juan Wang, Xiao-Ling Xu, Xiao-Ying Ying, Sai-Ping Jiang, Jian You & Yong-Zhong Du. (2018) CD44-targeted hyaluronic acid-curcumin prodrug protects renal tubular epithelial cell survival from oxidative stress damage. Carbohydrate Polymers 193, pages 268-280.
Crossref
Tian-ru Jin. (2018) Curcumin and dietary polyphenol research: beyond drug discovery. Acta Pharmacologica Sinica 39:5, pages 779-786.
Crossref
Jun-Xia Zhang, Xin-Liang Qu, Peng Chu, Du-Jiang Xie, Lin-Lin Zhu, Yue-Lin Chao, Li Li, Jun-Jie Zhang & Shao-Liang Chen. (2018) Low shear stress induces vascular eNOS uncoupling via autophagy-mediated eNOS phosphorylation. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1865:5, pages 709-720.
Crossref
Haipeng Yin, Qiang Guo, Xin Li, Tiantian Tang, Cuiling Li, Hengxiao Wang, Yuanxin Sun, Qi Feng, Chunhong Ma, Chengjiang Gao, Fan Yi & Jun Peng. (2018) Curcumin Suppresses IL-1β Secretion and Prevents Inflammation through Inhibition of the NLRP3 Inflammasome. The Journal of Immunology 200:8, pages 2835-2846.
Crossref
Candice E. Van Skike, Jordan B. Jahrling, Angela B. Olson, Naomi L. Sayre, Stacy A. Hussong, Zoltan Ungvari, James D. Lechleiter & Veronica Galvan. (2018) Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer’s disease and vascular cognitive impairment. American Journal of Physiology-Heart and Circulatory Physiology 314:4, pages H693-H703.
Crossref
Ying Tang, Hong Wu, Bozhong Shao, Yeqing Wang, Chong Liu & Meili Guo. (2018) Celosins inhibit atherosclerosis in ApoE-/- mice and promote autophagy flow. Journal of Ethnopharmacology 215, pages 74-82.
Crossref
Cheng-kun Wang, Muhammad Masood Ahmed, Quan Jiang, Nan-nan Lu, Chao Tan, Yin-ping Gao, Qaisar Mahmood, Dan-yang Chen, Kohji Fukunaga, Mei Li, Zhong Chen, Christopher S. Wilcox, Ying-mei Lu, Zheng-hong Qin & Feng Han. (2017) Melatonin ameliorates hypoglycemic stress-induced brain endothelial tight junction injury by inhibiting protein nitration of TP53-induced glycolysis and apoptosis regulator. Journal of Pineal Research 63:4, pages e12440.
Crossref
Ying Wei, Jiaqi Gao, Lingling Qin, Yunling Xu, Haoxia Shi, Lingxia Qu, Yongqiao Liu, Tunhai Xu & Tonghua Liu. (2017) Curcumin suppresses AGEs induced apoptosis in tubular epithelial cells via protective autophagy. Experimental and Therapeutic Medicine.
Crossref
Zhiwei Zhao, Xiaoling Li & Qing Li. (2017) Curcumin accelerates the repair of sciatic nerve injury in rats through reducing Schwann cells apoptosis and promoting myelinization. Biomedicine & Pharmacotherapy 92, pages 1103-1110.
Crossref
C Yang, X Zhang, J Gao, M Wang & Z Yang. (2017) Arginine vasopressin ameliorates spatial learning impairments in chronic cerebral hypoperfusion via V1a receptor and autophagy signaling partially. Translational Psychiatry 7:7, pages e1174-e1174.
Crossref
Wensi Fan, Dong Han, Zhongchan Sun, Sai Ma, Lei Gao, Jiangwei Chen, Xiang Li, Xiujuan Li, Miaomiao Fan, Congye Li, Dahai Hu, Yabin Wang & Feng Cao. (2017) Endothelial deletion of mTORC1 protects against hindlimb ischemia in diabetic mice via activation of autophagy, attenuation of oxidative stress and alleviation of inflammation. Free Radical Biology and Medicine 108, pages 725-740.
Crossref
Rachel Botchlett, Shih-Lung Woo, Mengyang Liu, Ya Pei, Xin Guo, Honggui Li & Chaodong Wu. (2017) Nutritional approaches for managing obesity-associated metabolic diseases. Journal of Endocrinology 233:3, pages R145-R171.
Crossref
Yun Luo, Xiangbao Meng, Ping Zhou, Shan Lu, Meng Qin, Xudong Xu, Guibo Sun & Xiaobo Sun. (2017) Elatoside C protects against ox-LDL-induced HUVECs injury by FoxO1-mediated autophagy induction. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1863:6, pages 1654-1665.
Crossref
Yu-Ning Zhu, Wen-Jing Fan, Chi Zhang, Fang Guo, Wei Li, Yu-Fei Wang, Zhi-Sheng Jiang & Shun-Lin Qu. (2017) Role of autophagy in advanced atherosclerosis. Molecular Medicine Reports 15:5, pages 2903-2908.
Crossref
Mahmoud Hashemzaei, Reza Entezari Heravi, Ramin Rezaee, Ali Roohbakhsh & Gholamreza Karimi. (2017) Regulation of autophagy by some natural products as a potential therapeutic strategy for cardiovascular disorders. European Journal of Pharmacology 802, pages 44-51.
Crossref
Chao Lin, Ying Lu, Xiaojing Yan, Xiang Wu, Meiyu Kuai, Xin Sun, Qi Chen, Xueyun Kong, Zhaoguo Liu, Yuping Tang, Yi Jing, Yu Li, Qichun Zhang & Huimin Bian. (2017) Catalpol protects glucose-deprived rat embryonic cardiac cells by inducing mitophagy and modulating estrogen receptor. Biomedicine & Pharmacotherapy 89, pages 973-982.
Crossref
Lu Zhang, Fang Dai, LiuQing Cui, Bo Zhou & YuQi Guo. (2017) Up-regulation of the active form of small GTPase Rab13 promotes macroautophagy in vascular endothelial cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1864:4, pages 613-624.
Crossref
Mao Ye, Hong Qiu, Yingkang Cao, Min Zhang, Yan Mi, Jing Yu & Changhua Wang. (2017) Curcumin Improves Palmitate-Induced Insulin Resistance in Human Umbilical Vein Endothelial Cells by Maintaining Proteostasis in Endoplasmic Reticulum. Frontiers in Pharmacology 8.
Crossref
Peiqi Wang, Lingjuan Zhu, Dejuan Sun, Feihong Gan, Suyu Gao, Yuanyuan Yin & Lixia Chen. (2016) Natural products as modulator of autophagy with potential clinical prospects. Apoptosis 22:3, pages 325-356.
Crossref
Yuanzhou He, Xiaopei Cao, Pujian Guo, Xiaochen Li, Huihui Shang, Jin Liu, Min Xie, Yongjian Xu & Xiansheng Liu. (2017) Quercetin induces autophagy via FOXO1-dependent pathways and autophagy suppression enhances quercetin-induced apoptosis in PASMCs in hypoxia. Free Radical Biology and Medicine 103, pages 165-176.
Crossref
Sin-Hye Park, Min-Kyung Kang, Yean-Jung Choi, Yun-Ho Kim, Lucia Dwi Antika, Dong Yeon Kim, Eun-Jung Lee, Soon Sung Lim & Young-Hee Kang. (2017) α-Asarone blocks 7β-hydroxycholesterol-exposed macrophage injury through blocking elF2α phosphorylation and prompting beclin-1-dependent autophagy. Oncotarget 8:5, pages 7370-7383.
Crossref
Jingyuan Li, Tongshuai Chen, Ming Xiao, Na Li, Shujian Wang, Hongyan Su, Xiaobin Guo, Hui Liu, Fangying Yan, Yi Yang, Yun Zhang & Peili Bu. (2016) Mouse Sirt3 promotes autophagy in AngII-induced myocardial hypertrophy through the deacetylation of FoxO1. Oncotarget 7:52, pages 86648-86659.
Crossref
Dan Li, Jun Wang, Jincai Hou, Jianhua Fu, Dennis Chang, Alan Bensoussan & Jianxun Liu. (2016) Ginsenoside Rg1 protects starving H9c2 cells by dissociation of Bcl-2-Beclin1 complex. BMC Complementary and Alternative Medicine 16:1.
Crossref
Jianbin Zhang, Jigang Wang, Jian Xu, Yuanqiang Lu, Jiukun Jiang, Liming Wang, Han-Ming Shen & Dajing Xia. (2016) Curcumin targets the TFEB-lysosome pathway for induction of autophagy. Oncotarget 7:46, pages 75659-75671.
Crossref
Fan Jiang. (2016) Autophagy in vascular endothelial cells. Clinical and Experimental Pharmacology and Physiology 43:11, pages 1021-1028.
Crossref
Rob De Vreese, Charlotte Grootaert, Sander D’hoore, Atiruj Theppawong, Sam Van Damme, Maarten Van Bogaert, John Van Camp & Matthias D’hooghe. (2016) Synthesis of novel curcuminoids accommodating a central β-enaminone motif and their impact on cell growth and oxidative stress. European Journal of Medicinal Chemistry 123, pages 727-736.
Crossref
Ahmed Abdal Dayem, Hye Choi, Gwang-Mo Yang, Kyeongseok Kim, Subbroto Saha & Ssang-Goo Cho. (2016) The Anti-Cancer Effect of Polyphenols against Breast Cancer and Cancer Stem Cells: Molecular Mechanisms. Nutrients 8:9, pages 581.
Crossref
Shaopeng Wang, Xiance Sun, Liping Jiang, Xiaofang Liu, Min Chen, Xiaofeng Yao, Qinghua Sun & Guang Yang. (2016) 6-Gingerol induces autophagy to protect HUVECs survival from apoptosis. Chemico-Biological Interactions 256, pages 249-256.
Crossref
Bin Wang, Wei Ding, Minmin Zhang, Hongmei Li, Honglei Guo, Lilu Lin, Jing Chen & Yong Gu. (2016) Role of FOXO1 in aldosterone-induced autophagy: A compensatory protective mechanism related to podocyte injury. Oncotarget 7:29, pages 45331-45351.
Crossref
Hanna Lewandowska, Monika Kalinowska, Włodzimierz Lewandowski, Tomasz M. Stępkowski & Kamil Brzóska. (2016) The role of natural polyphenols in cell signaling and cytoprotection against cancer development. The Journal of Nutritional Biochemistry 32, pages 1-19.
Crossref
Jun GuoYaxiong SangTao YinBo WangWenping YangXue Li, Huan Li & Yan Kang. (2016) miR-1273g-3p participates in acute glucose fluctuation-induced autophagy, dysfunction, and proliferation attenuation in human umbilical vein endothelial cells. American Journal of Physiology-Endocrinology and Metabolism 310:9, pages E734-E743.
Crossref
Mireia Casasampere, Yadira F. Ordoñez, Ana Pou & Josefina Casas. (2016) Inhibitors of dihydroceramide desaturase 1: Therapeutic agents and pharmacological tools to decipher the role of dihydroceramides in cell biology. Chemistry and Physics of Lipids 197, pages 33-44.
Crossref
Hua Ning, Zongxiang Sun, Yunyun Liu, Lei Liu, Liuyi Hao, Yaxin Ye, Rennan Feng, Jie Li, Ying Li, Xia Chu, Songtao Li & Changhao Sun. (2016) Insulin Protects Hepatic Lipotoxicity by Regulating ER Stress through the PI3K/Akt/p53 Involved Pathway Independently of Autophagy Inhibition. Nutrients 8:4, pages 227.
Crossref
N. K. Zenkov, A. V. Chechushkov, P. M. Kozhin, N. V. Kandalintseva, G. G. Martinovich & E. B. Menshchikova. (2016) Plant phenols and autophagy. Biochemistry (Moscow) 81:4, pages 297-314.
Crossref
Jessica L. Fetterman, Monica Holbrook, Nir Flint, Bihua Feng, Rosa Bretόn-Romero, Erika A. Linder, Brittany D. Berk, Mai-Ann Duess, Melissa G. Farb, Noyan Gokce, Orian S. Shirihai, Naomi M. Hamburg & Joseph A. Vita. (2016) Restoration of autophagy in endothelial cells from patients with diabetes mellitus improves nitric oxide signaling. Atherosclerosis 247, pages 207-217.
Crossref
Jiaxiang Shao, Xiao Yang, Tengyuan Liu, Tingting Zhang, Qian Reuben Xie & Weiliang Xia. (2016) Autophagy induction by SIRT6 is involved in oxidative stress-induced neuronal damage. Protein & Cell 7:4, pages 281-290.
Crossref
Shutao Yin, Xiao Guo, Jinghua Li, Linghong Fan & Hongbo Hu. (2015) Fumonisin B1 induces autophagic cell death via activation of ERN1-MAPK8/9/10 pathway in monkey kidney MARC-145 cells. Archives of Toxicology 90:4, pages 985-996.
Crossref
Yun Luo, Shan Lu, Ping Zhou, Qi-Di Ai, Gui-Bo Sun & Xiao-Bo Sun. (2016) Autophagy. Journal of Cardiovascular Pharmacology 67:3, pages 266-274.
Crossref
WENBIN DONG, SHIGENG XIAO, MIN CHENG, XIAODI YE & GAOLI ZHENG. (2016) Minocycline induces protective autophagy in vascular endothelial cells exposed to an in vitro model of ischemia/reperfusion-induced injury. Biomedical Reports 4:2, pages 173-177.
Crossref
Jigang Wang, Jianbin Zhang, Chong-Jing Zhang, Yin Kwan Wong, Teck Kwang Lim, Zi-Chun Hua, Bin Liu, Steven R. Tannenbaum, Han-Ming Shen & Qingsong Lin. (2016) In situ Proteomic Profiling of Curcumin Targets in HCT116 Colon Cancer Cell Line. Scientific Reports 6:1.
Crossref
Yunkyoung Lee, Hee-Sook Jun & Yoon Sin Oh. (2016) Protective Effect of Psoralea corylifolia L. Seed Extract against Palmitate-Induced Neuronal Apoptosis in PC12 Cells . Evidence-Based Complementary and Alternative Medicine 2016, pages 1-11.
Crossref
Chih-Yang Chang, Po-Han Chen, Shang-Chieh Lu, Ming-Chu Hsieh, Chia-Wei Lin, Hui-Ming Lee, Bruno Jawan & Ying-Hsien Kao. (2015) Propofol-enhanced autophagy increases motility and angiogenic capacity of cultured human umbilical vascular endothelial cells. Life Sciences 142, pages 49-59.
Crossref
Monika Bhardwaj, Souren Paul, Rekha Jakhar & Sun Chul Kang. (2015) Potential role of vitexin in alleviating heat stress-induced cytotoxicity: Regulatory effect of Hsp90 on ER stress-mediated autophagy. Life Sciences 142, pages 36-48.
Crossref
Xiaochun Ma, Rongfang Qiu, Jie Dang, Jiangxia Li, Qin Hu, Shan Shan, Qian Xin, Wenying Pan, Xianli Bian, Qianqian Yuan, Feng Long, Na Liu, Yan Li, Fei Gao, Chengwei Zou, Yaoqin Gong & Qiji Liu. (2015) ORMDL3 contributes to the risk of atherosclerosis in Chinese Han population and mediates oxidized low-density lipoprotein-induced autophagy in endothelial cells. Scientific Reports 5:1.
Crossref
Feng Hao, Jinsen Kang, Yajun Cao, Shengjun Fan, Haopeng Yang, Yu An, Yan Pan, Lu Tie & Xuejun Li. (2015) Curcumin attenuates palmitate-induced apoptosis in MIN6 pancreatic β-cells through PI3K/Akt/FoxO1 and mitochondrial survival pathways. Apoptosis 20:11, pages 1420-1432.
Crossref
Delinaer Wuerkenbieke, Jing Wang, Yan Li & Cailing Ma. (2015) miRNA-150 downregulation promotes pertuzumab resistance in ovarian cancer cells via AKT activation. Archives of Gynecology and Obstetrics 292:5, pages 1109-1116.
Crossref
Jianhua Xiong. (2015) Atg7 in development and disease: panacea or Pandora’s Box?. Protein & Cell 6:10, pages 722-734.
Crossref
J Liu, X Bi, T Chen, Q Zhang, S-X Wang, J-J Chiu, G-S Liu, Y Zhang, P Bu & F Jiang. (2015) Shear stress regulates endothelial cell autophagy via redox regulation and Sirt1 expression. Cell Death & Disease 6:7, pages e1827-e1827.
Crossref
Yu-Juei Hsu, Shih-Che Hsu, Shih-Ming Huang, Herng-Sheng Lee, Shih-Hua Lin, Chien-Sung Tsai, Chun-Che Shih & Chih-Yuan Lin. (2015) Hyperphosphatemia induces protective autophagy in endothelial cells through the inhibition of Akt/mTOR signaling. Journal of Vascular Surgery 62:1, pages 210-221.e2.
Crossref
Xiaolong Hou, Qing Tong, Wenqing Wang, Wei Xiong, Chunyang Shi & Jianguo Fang. (2015) Dihydromyricetin protects endothelial cells from hydrogen peroxide-induced oxidative stress damage by regulating mitochondrial pathways. Life Sciences 130, pages 38-46.
Crossref
Chi-Cheng Lu & Gow-Chin Yen. (2015) Antioxidative and anti-inflammatory activity of functional foods. Current Opinion in Food Science 2, pages 1-8.
Crossref
TAO MA, LU YANG & JIN ZHANG. (2015) miRNA-542-3p downregulation promotes trastuzumab resistance in breast cancer cells via AKT activation. Oncology Reports 33:3, pages 1215-1220.
Crossref
Lu Zhang, Fang Dai, LiuQing Cui, Hongjuan Jing, Pei Fan, Xiaorong Tan, YuQi Guo & GuangZhou Zhou. (2015) Novel role for TRPC4 in regulation of macroautophagy by a small molecule in vascular endothelial cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1853:2, pages 377-387.
Crossref
Qian Ding, Jiaolin Bao, Wenwen Zhao, Yangyang Hu, Jinjian Lu & Xiuping Chen. (2014) Natural autophagy regulators in cancer therapy: a review. Phytochemistry Reviews 14:1, pages 137-154.
Crossref
Guido R.Y. De MeyerMandy O.J. GrootaertCédéric F. MichielsAmmar KurdiDorien M. SchrijversWim Martinet. (2015) Autophagy in Vascular Disease. Circulation Research 116:3, pages 468-479.
Crossref
Chenjun Hao, Zhengpeng Yang, Bo Gao, Ming Lu, Xianzhi Meng, Xin Qiao, Dongbo Xue & Weihui Zhang. (2014) Database screening of herbal monomers regulating autophagy by constructing a "disease-gene-drug" network. BMC Complementary and Alternative Medicine 14:1.
Crossref
Yingbo Li, Jinxi Wang, Xing Gao, Weihua Han, Yongxiang Zheng, Huan Xu, Chuanling Zhang, Qiuchen He, Lihe Zhang, Zhongxin Li & Demin Zhou. (2014) c-Met Targeting Enhances the Effect of Irradiation and Chemical Agents against Malignant Colon Cells Harboring a KRAS Mutation. PLoS ONE 9:11, pages e113186.
Crossref
Hong-Feng Gu, Ya-Xiong Nie, Qiao-Zhen Tong, Ya-Ling Tang, Yang Zeng, Kai-Quan Jing, Xi-Long Zheng & Duan-Fang Liao. (2014) Epigallocatechin-3-Gallate Attenuates Impairment of Learning and Memory in Chronic Unpredictable Mild Stress-Treated Rats by Restoring Hippocampal Autophagic Flux. PLoS ONE 9:11, pages e112683.
Crossref
N Hasima & B Ozpolat. (2014) Regulation of autophagy by polyphenolic compounds as a potential therapeutic strategy for cancer. Cell Death & Disease 5:11, pages e1509-e1509.
Crossref
Kuan-Wei Lee, Varadharajan Thiyagarajan, Huei-Wun Sie, Ming-Fan Cheng, May-Jywan Tsai, Yi-Chen Chia & Ching-Feng Weng. (2014) Synergistic effect of natural compounds on the fatty acid-induced autophagy of activated hepatic stellate cells. The Journal of Nutritional Biochemistry 25:9, pages 903-913.
Crossref
Xiao-Li Tian & Yang Li. (2014) Endothelial Cell Senescence and Age-Related Vascular Diseases. Journal of Genetics and Genomics 41:9, pages 485-495.
Crossref
Lei Yang, Xuping Wang & Xiaolan Yang. (2014) Possible Antioxidant Mechanism of Melanoidins Extract from Shanxi Aged Vinegar in Mitophagy-Dependent and Mitophagy-Independent Pathways. Journal of Agricultural and Food Chemistry 62:34, pages 8616-8622.
Crossref
SeungHoon Lee, Yuuki Hiradate, Yumi Hoshino, Kentaro Tanemura & Eimei Sato. (2013) Quantitative analysis in LC3-II protein in vitro maturation of porcine oocyte . Zygote 22:3, pages 404-410.
Crossref
Hee Ju Kim, Joonki Kim, Ki Sung Kang, Keun Taik Lee & Hyun Ok Yang. (2014) Neuroprotective Effect of Chebulagic Acid via Autophagy Induction in SH-SY5Y Cells. Biomolecules & Therapeutics 22:4, pages 275-281.
Crossref
Yingxin Pang, Manfei Si, Bin Sun, Leilei Niu, Xia Xu, Tao Lu, Huiqing Yuan & Hongxiang Lou. (2014) DHA2, a synthesized derivative of bisbibenzyl, exerts antitumor activity against ovarian cancer through inhibition of XIAP and Akt/mTOR pathway. Food and Chemical Toxicology 69, pages 163-174.
Crossref
Sina Kardeh, Soheil Ashkani-Esfahani & Ali Mohammad Alizadeh. (2014) Paradoxical action of reactive oxygen species in creation and therapy of cancer. European Journal of Pharmacology 735, pages 150-168.
Crossref
Jia Xu, Kexin Meng, Rui Zhang, He Yang, Chang Liao, Wenliang Zhu & Jundong Jiao. (2014) The Use of Functional Chemical-Protein Associations to Identify Multi-Pathway Renoprotectants. PLoS ONE 9:5, pages e97906.
Crossref
X Ao, L Zou & Y Wu. (2014) Regulation of autophagy by the Rab GTPase network. Cell Death & Differentiation 21:3, pages 348-358.
Crossref
Rama Malaviya, Jeffrey D. Laskin & Debra L. Laskin. (2014) Oxidative stress-induced autophagy: Role in pulmonary toxicity. Toxicology and Applied Pharmacology 275:2, pages 145-151.
Crossref
Tomasz Urbanek, Wacław Kuczmik, Agnieszka Basta-Kaim & Bożena Gabryel. (2014) Rapamycin induces of protective autophagy in vascular endothelial cells exposed to oxygen–glucose deprivation. Brain Research 1553, pages 1-11.
Crossref
H He, X Liu, L Lv, H Liang, B Leng, D Zhao, Y Zhang, Z Du, X Chen, S Li, Y Lu & H Shan. (2014) Calcineurin suppresses AMPK-dependent cytoprotective autophagy in cardiomyocytes under oxidative stress. Cell Death & Disease 5:1, pages e997-e997.
Crossref
Jia-Ching Wu, Mei-Ling Tsai, Ching-Shu Lai, Ying-Jan Wang, Chi-Tang Ho & Min-Hsiung Pan. (2014) Chemopreventative effects of tetrahydrocurcumin on human diseases. Food Funct. 5:1, pages 12-17.
Crossref
Kameswaran Ravichandran & Charles L. Edelstein. (2014) Polycystic Kidney Disease: A Case of Suppressed Autophagy?. Seminars in Nephrology 34:1, pages 27-33.
Crossref
Kris Nys, Séverine Vermeire & Patrizia Agostinis. 2014. Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging 69 77 .
Fan Jiang. 2014. Polyphenols in Human Health and Disease. Polyphenols in Human Health and Disease 947 962 .
Matheus Correa-Costa & Leo E. Otterbein. 2014. Pharma-Nutrition. Pharma-Nutrition 243 256 .
Jai-Sing Yang. (2013) Curcumin-loaded nanoparticles enhance apoptotic cell death of U2OS human osteosarcoma cells through the Akt-Bad signaling pathway. International Journal of Oncology.
Crossref
Keping Yang, Chenhong Xu, Xin Li & Hong Jiang. (2013) Combination of D942 With Curcumin Protects Cardiomyocytes From Ischemic Damage Through Promoting Autophagy. Journal of Cardiovascular Pharmacology and Therapeutics 18:6, pages 570-581.
Crossref
Yi-Bo Zhang, Wei Zhao & Rui-Xia Zeng. (2013) Autophagic Degradation of Caspase-8 Protects U87MG Cells Against H 2 O 2 -induced Oxidative Stress . Asian Pacific Journal of Cancer Prevention 14:7, pages 4095-4099.
Crossref
Kris Nys, Patrizia Agostinis & Séverine Vermeire. (2013) Autophagy: a new target or an old strategy for the treatment of Crohn's disease?. Nature Reviews Gastroenterology & Hepatology 10:7, pages 395-401.
Crossref
Yong-Ning Deng, Jie Shi, Jie Liu & Qiu-Min Qu. (2013) Celastrol protects human neuroblastoma SH-SY5Y cells from rotenone-induced injury through induction of autophagy. Neurochemistry International 63:1, pages 1-9.
Crossref
Dima A. Youssef, Alan N. Peiris, Jim L. Kelley & William B. Grant. (2013) The possible roles of vitamin D and curcumin in treating gonorrhea. Medical Hypotheses 81:1, pages 131-135.
Crossref
Mi Zhou & Renxiao Wang. (2013) Small‐Molecule Regulators of Autophagy and Their Potential Therapeutic Applications. ChemMedChem 8:5, pages 694-707.
Crossref
Yang Yang, Weixun Duan, Zhenxin Liang, Wei Yi, Juanjuan Yan, Ning Wang, Yue Li, Wensheng Chen, Shiqiang Yu, Zhenxiao Jin & Dinghua Yi. (2013) Curcumin attenuates endothelial cell oxidative stress injury through Notch signaling inhibition. Cellular Signalling 25:3, pages 615-629.
Crossref
Akira Murakami. (2013) Modulation of protein quality control systems by food phytochemicals. Journal of Clinical Biochemistry and Nutrition 52:3, pages 215-227.
Crossref
Anchalee Prasansuklab & Tewin Tencomnao. (2013) Amyloidosis in Alzheimer’s Disease: The Toxicity of Amyloid Beta (A β ), Mechanisms of Its Accumulation and Implications of Medicinal Plants for Therapy . Evidence-Based Complementary and Alternative Medicine 2013, pages 1-10.
Crossref
Xiwen Xiong, Rongya Tao, Ronald A. DePinho & X.Charlie Dong. (2012) The Autophagy-related Gene 14 (Atg14) Is Regulated by Forkhead Box O Transcription Factors and Circadian Rhythms and Plays a Critical Role in Hepatic Autophagy and Lipid Metabolism. Journal of Biological Chemistry 287:46, pages 39107-39114.
Crossref
Lei He, Cheng-Lin Zhang, Qinghua Chen, Li Wang & Yu Huang. (2021) Endothelial Shear Stress and Atherosclerosis: From Mechanisms to Therapeutics. SSRN Electronic Journal.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.