Citations (56)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (6)
Shovonlal Bhowmick, Kunal Roy & Achintya Saha. (2022) Exploring CIP2A modulators using multiple molecular modeling approaches. Journal of Biomolecular Structure and Dynamics 40:3, pages 1048-1063.
Read now
Read now
Shu-Hui Lin, Hsin-Kai Wang, Kun-Tu Yeh, Hui-Chun Tai, Hui-Yi Wang, Lan-Ru Huang, Chun-Wen Chiu, Chia-Min Chung & Bharath Kumar Velmurugan. (2019) c-MYC expression in T (III/IV) stage oral squamous cell carcinoma (OSCC) patients. Cancer Management and Research 11, pages 5163-5169.
Read now
Read now
Shijie Li, Tu Hu, Ting Yuan, Dongdong Cheng & Qingcheng Yang. (2018) Nucleoside diphosphate kinase B promotes osteosarcoma proliferation through c-Myc. Cancer Biology & Therapy 19:7, pages 565-572.
Read now
Read now
Geqi Cha, Jianyu Xu, Xiangying Xu, Bin Li, Shan Lu, Abiyasi Nanding, Songliu Hu & Shilong Liu. (2017) High expression of CIP2A protein is associated with tumor aggressiveness in stage I–III NSCLC and correlates with poor prognosis. OncoTargets and Therapy 10, pages 5907-5914.
Read now
Read now
Kaisa Ahopelto, Camilla Böckelman, Jaana Hagström, Selja Koskensalo & Caj Haglund. (2016) Transketolase-like protein 1 expression predicts poor prognosis in colorectal cancer. Cancer Biology & Therapy 17:2, pages 163-168.
Read now
Read now
Rajash Pallai, Aishwarya Bhaskar, Valerie Sodi & Lyndi M. Rice. (2012) Ets1 and Elk1 transcription factors regulate cancerous inhibitor of protein phosphatase 2A expression in cervical and endometrial carcinoma cells. Transcription 3:6, pages 323-335.
Read now
Read now
Articles from other publishers (50)
Kiran Jot, Vivek Nayyar, Varun Surya, Ajoy Roychoudhury & Deepika Mishra. (2023) Clinicopathological comparison and assessment of Ki67, p53 and c-myc immunoexpression in carcinoma cuniculatum, verrucous carcinoma and microinvasive squamous cell carcinoma of the oral cavity. Oral Oncology Reports 8, pages 100109.
Crossref
Crossref
Suyasha Roy & Lalit Batra. (2023) Protein Phosphatase 2A: Role in T Cells and Diseases. Journal of Immunology Research 2023, pages 1-11.
Crossref
Crossref
Beibei Chen, Huihui Hu & Xiaobing Chen. (2023) From Basic Science to Clinical Practice: The Role of Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A)/p90 in Cancer. Frontiers in Genetics 14.
Crossref
Crossref
Elham Kashani & Erik Vassella. (2022) Pleiotropy of PP2A Phosphatases in Cancer with a Focus on Glioblastoma IDH Wildtype. Cancers 14:21, pages 5227.
Crossref
Crossref
Li Tan, Dong Peng & Yong Cheng. (2022) Significant position of C-myc in colorectal cancer: a promising therapeutic target. Clinical and Translational Oncology 24:12, pages 2295-2304.
Crossref
Crossref
Mohammad M. Tarek, Ahmed Yahia, Mostafa M. El-Nakib & Mahmoud Elhefnawi. (2021) Integrative assessment of CIP2A overexpression and mutational effects in human malignancies identifies possible deleterious variants. Computers in Biology and Medicine 139, pages 104986.
Crossref
Crossref
Ekaterina Mikhailovna Stasevich, Matvey Mikhailovich Murashko, Lyudmila Sergeevna Zinevich, Denis Eriksonovich Demin & Anton Markovich Schwartz. (2021) The Role of Non-Coding RNAs in the Regulation of the Proto-Oncogene MYC in Different Types of Cancer. Biomedicines 9:8, pages 921.
Crossref
Crossref
Hyo‐Eun Son & Won‐Gu Jang. (2021)
Cip2A
modulates osteogenic differentiation via the
ERK‐Runx2
pathway in
MG63
cells
. BioFactors 47:4, pages 658-664.
Crossref
Crossref
Wei Chen, Jing-Lin Liang, Kai Zhou, Qing-Li Zeng, Jun-Wen Ye & Mei-Jin Huang. (2020) Effect of CIP2A and its mechanism of action in the malignant biological behavior of colorectal cancer. Cell Communication and Signaling 18:1.
Crossref
Crossref
Katja Kaipio, Ping Chen, Pia Roering, Kaisa Huhtinen, Piia Mikkonen, Päivi Östling, Laura Lehtinen, Naziha Mansuri, Taina Korpela, Swapnil Potdar, Johanna Hynninen, Annika Auranen, Seija Grénman, Krister Wennerberg, Sampsa Hautaniemi & Olli Carpén. (2019) ALDH1A1‐related stemness in high‐grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR‐PI3K/aurora kinase inhibitors. The Journal of Pathology 250:2, pages 159-169.
Crossref
Crossref
Song Hee Kim, Won Hyeok Lee, Daseul Seong, Jae Hee An, Hyoung Uk Je, Hae Yun Nam, Sang Yoon Kim, Seong Who Kim & Myung Woul Han. (2019) The role of CIP2A as a therapeutic target of rapamycin in radioresistant head and neck cancer with TP53 mutation. Head & Neck 41:9, pages 3362-3371.
Crossref
Crossref
Khadija Slik, Sami Blom, Riku Turkki, Katja Välimäki, Samu Kurki, Harri Mustonen, Caj Haglund, Olli Carpén, Olli Kallioniemi, Eija Korkeila, Jari Sundström & Teijo Pellinen. (2019) Combined epithelial marker analysis of tumour budding in stage II colorectal cancer. The Journal of Pathology: Clinical Research 5:1, pages 63-78.
Crossref
Crossref
Hirota Fujiki, Eisaburo Sueoka, Tatsuro Watanabe & Masami Suganuma. (2018) The concept of the okadaic acid class of tumor promoters is revived in endogenous protein inhibitors of protein phosphatase 2A, SET and CIP2A, in human cancers. Journal of Cancer Research and Clinical Oncology 144:12, pages 2339-2349.
Crossref
Crossref
Wei-Ling He, Xiang-Tao Weng, Jue-Lian Wang, Yong-Kai Lin, Tian-Wen Liu, Qian-Yi Zhou, Yue Hu, Yunbao Pan & Xin-Lin Chen. (2018) Association Between c-Myc and Colorectal Cancer Prognosis: A Meta-Analysis. Frontiers in Physiology 9.
Crossref
Crossref
Chun‐Yu Liu, Chia‐Chi Hsu, Tzu‐Ting Huang, Chia‐Han Lee, Ji‐Lin Chen, Shung‐Haur Yang, Jeng‐Kai Jiang, Wei‐Shone Chen, Kuan‐Der Lee & Hao‐Wei Teng. (2018)
ER
stress‐related
ATF
6 upregulates
CIP
2A and contributes to poor prognosis of colon cancer
. Molecular Oncology 12:10, pages 1706-1717.
Crossref
Crossref
Ning Wang, Fang Zhou, Jinhui Guo, Huaiyuan Zhu, Shanshui Luo & Jingjing Cao. (2018) Euxanthone suppresses tumor growth and metastasis in colorectal cancer via targeting CIP2A/PP2A pathway. Life Sciences 209, pages 498-506.
Crossref
Crossref
Min Tang, Jiao-Feng Shen, Ping Li, Li-Na Zhou, Ping Zeng, Xi-Xi Cui, Min-Bin Chen & Ye Tian. (2018) Prognostic significance of CIP2A expression in solid tumors: A meta-analysis. PLOS ONE 13:7, pages e0199675.
Crossref
Crossref
Eva-Maria Birkman, Adam Elzagheid, Terhi Jokilehto, Tuulia Avoranta, Eija Korkeila, Jarmo Kulmala, Kari Syrjänen, Jukka Westermarck & Jari Sundström. (2018) Protein phosphatase 2A (PP2A) inhibitor CIP2A indicates resistance to radiotherapy in rectal cancer. Cancer Medicine 7:3, pages 698-706.
Crossref
Crossref
Ning Yu, TingGuo Zhang, DaHua Zhao, Zhang Cao, Jing Du & Qian Zhang. (2018) CIP2A is overexpressed in human endometrioid adenocarcinoma and regulates cell proliferation, invasion and apoptosis. Pathology - Research and Practice 214:2, pages 233-239.
Crossref
Crossref
Chun-Yu Liu, Feng-Shu Hsieh, Pei-Yi Chu, Wen-Chun Tsai, Chun-Teng Huang, Yuan-Bin Yu, Tzu-Ting Huang, Po-Shen Ko, Man-Hsin Hung, Wan-Lun Wang, Chung-Wai Shiau & Kuen-Feng Chen. (2017) Carfilzomib induces leukaemia cell apoptosis via inhibiting ELK1/KIAA1524 (Elk-1/CIP2A) and activating PP2A not related to proteasome inhibition. British Journal of Haematology 177:5, pages 726-740.
Crossref
Crossref
Weimin Wang, Jianliang Deng, Qianqian Wang, Qiang Yao, Wenjiao Chen, Yongfei Tan, Zhijun Ge, Jianwei Zhou & Yan Zhou. (2017) Synergistic role of Cul1 and c-Myc: Prognostic and predictive biomarkers in colorectal cancer. Oncology Reports.
Crossref
Crossref
H Liu, H Qiu, Y Song, Y Liu, H Wang, M Lu, M Deng, Y Gu, J Yin, K Luo, Z Zhang, X Jia, G Zheng & Z He. (2016) Cip2a promotes cell cycle progression in triple-negative breast cancer cells by regulating the expression and nuclear export of p27Kip1. Oncogene 36:14, pages 1952-1964.
Crossref
Crossref
JUAN LI, SHU-WEI WANG, DONG-SHENG ZHANG, YE SUN, CHUN-YAN ZHU, QIANG FEI, JUN HU, CHUAN ZHANG & YUE-MING SUN. (2016) FTY720-induced enhancement of autophagy protects cells from FTY720 cytotoxicity in colorectal cancer. Oncology Reports 35:5, pages 2833-2842.
Crossref
Crossref
Jaya Sangodkar, Caroline C. Farrington, Kimberly McClinch, Matthew D. Galsky, David B. Kastrinsky & Goutham Narla. (2016) All roads lead to PP2A: exploiting the therapeutic potential of this phosphatase. FEBS Journal 283:6, pages 1004-1024.
Crossref
Crossref
Dale L. Ang, Benjamin W. J. Harper, Leticia Cubo, Oscar Mendoza, Ramon Vilar & Janice Aldrich‐Wright. (2015) Quadruplex DNA‐Stabilising Dinuclear Platinum(II) Terpyridine Complexes with Flexible Linkers. Chemistry – A European Journal 22:7, pages 2317-2325.
Crossref
Crossref
Anchit Khanna & John E. Pimanda. (2016) Clinical significance of cancerous inhibitor of protein phosphatase 2A in human cancers. International Journal of Cancer 138:3, pages 525-532.
Crossref
Crossref
Miia Seppälä, Sanni Tervo, Konsta Pohjola, Jussi Laranne, Heini Huhtala, Sanna Toppila-Salmi & Timo Paavonen. (2015) The association and prognostic relevance of cancerous inhibitor of protein phosphatase 2A and inflammation in tongue squamous cell carcinoma. APMIS 123:12, pages 1007-1015.
Crossref
Crossref
Rajash Pallai, Aishwarya Bhaskar, Natalie Barnett-Bernodat, Christina Gallo-Ebert, Michelle Pusey, Joseph T. Nickels & Lyndi M. Rice. (2015) Leucine-rich repeat-containing protein 59 mediates nuclear import of cancerous inhibitor of PP2A in prostate cancer cells. Tumor Biology 36:8, pages 6383-6390.
Crossref
Crossref
Vivi Ann Flørenes, Elisabeth Emilsen, Hiep Phuc Dong, Mette Førsund, Ruth Holm & Ana Slipicevic. (2015) Cellular localization of CIP2A determines its prognostic impact in superficial spreading and nodular melanoma. Cancer Medicine 4:6, pages 903-913.
Crossref
Crossref
Tuomas Kaprio, Tero Satomaa, Annamari Heiskanen, Cornelis H. Hokke, André M. Deelder, Harri Mustonen, Jaana Hagström, Olli Carpen, Juhani Saarinen & Caj Haglund. (2015) N-glycomic Profiling as a Tool to Separate Rectal Adenomas from Carcinomas*. Molecular & Cellular Proteomics 14:2, pages 277-288.
Crossref
Crossref
Yi Wu, Ting-Ting Gu & Peng-Sheng Zheng. (2015) CIP2A cooperates with H-Ras to promote epithelial–mesenchymal transition in cervical-cancer progression. Cancer Letters 356:2, pages 646-655.
Crossref
Crossref
Tuomas Kaprio, Jaana Hagström, Harri Mustonen, Selja Koskensalo, Leif C. Andersson & Caj Haglund. (2014) REG4 Independently Predicts Better Prognosis in Non-Mucinous Colorectal Cancer. PLoS ONE 9:10, pages e109600.
Crossref
Crossref
HYE-RIM LEE, KYUNG-A HWANG & KYUNG-CHUL CHOI. (2014) The estrogen receptor signaling pathway activated by phthalates is linked with transforming growth factor-β in the progression of LNCaP prostate cancer models. International Journal of Oncology 45:2, pages 595-602.
Crossref
Crossref
Pradip De, Jennifer Carlson, Brian Leyland-Jones & Nandini Dey. (2014) Oncogenic nexus of cancerous inhibitor of protein phosphatase 2A (CIP2A): An oncoprotein with many hands. Oncotarget 5:13, pages 4581-4602.
Crossref
Crossref
Yayun Ding, Yueguo Wang, Shaoqing Ju, Xinghua� Wu, Wencai Zhu, Feng Shi & Liping Mao. (2014) Role of CIP2A in the antitumor effect of bortezomib in colon cancer. Molecular Medicine Reports.
Crossref
Crossref
Ion Cristóbal, Rebeca Manso, Raúl Rincón, Cristina Caramés, Clara Senin, Aurea Borrero, Javier Martínez-Useros, María Rodriguez, Sandra Zazo, Oscar Aguilera, Juan Madoz-Gúrpide, Federico Rojo & Jesús García-Foncillas. (2014) PP2A Inhibition Is a Common Event in Colorectal Cancer and Its Restoration Using FTY720 Shows Promising Therapeutic Potential. Molecular Cancer Therapeutics 13:4, pages 938-947.
Crossref
Crossref
Hsei-Wei Wang, Shung-Haur Yang, Guan-Da Huang, Jen-Kou Lin, Wei-Shone Chen, Jeng-Kai Jiang, Yuan-Tzu Lan, Chun-Chi Lin, Wei-Lun Hwang, Cheng-Hwai Tzeng, Anna Fen-Yau Li, Chueh-Chuan Yen & Hao-Wei Teng. (2014) Temsirolimus enhances the efficacy of cetuximab in colon cancer through a CIP2A-dependent mechanism. Journal of Cancer Research and Clinical Oncology 140:4, pages 561-571.
Crossref
Crossref
Xinxin Liu, Yurong Chai, Jitian Li, Pengfei Ren, Mei Liu, Liping Dai, Wei Qian, Wenjie Li & Jian-Ying Zhang. (2014) Autoantibody response to a novel tumor-associated antigen p90/CIP2A in breast cancer immunodiagnosis. Tumor Biology 35:3, pages 2661-2667.
Crossref
Crossref
Mo Zhai, Lin Cong, Yaxin Han & Guanjun Tu. (2013) CIP2A is overexpressed in osteosarcoma and regulates cell proliferation and invasion. Tumor Biology 35:2, pages 1123-1128.
Crossref
Crossref
Y. A. Choi, J. S. Koo, J. S. Park, M. Y. Park, A. L. Jeong, K.-S. Oh & Y. Yang. (2013) Estradiol enhances CIP2A expression by the activation of p70 S6 kinase. Endocrine Related Cancer 21:2, pages 189-202.
Crossref
Crossref
Ae Lee Jeong, Sunyi Lee, Jeong Su Park, Sora Han, Chang-Young Jang, Jong-Seok Lim, Myung Sok Lee & Young Yang. (2014) Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A) Protein Is Involved in Centrosome Separation through the Regulation of NIMA (Never In Mitosis Gene A)-related Kinase 2 (NEK2) Protein Activity. Journal of Biological Chemistry 289:1, pages 28-40.
Crossref
Crossref
Armin Wiegering, Christina Pfann, Friedrich Wilhelm Uthe, Christoph Otto, Lukas Rycak, Uwe Mäder, Martin Gasser, Anna-Maria Waaga-Gasser, Martin Eilers & Christoph-Thomas Germer. (2013) CIP2A Influences Survival in Colon Cancer and Is Critical for Maintaining Myc Expression. PLoS ONE 8:10, pages e75292.
Crossref
Crossref
Laura Lilja, Kirsi-Maria Haapasaari, Risto Bloigu, Tarja Salonen, Ari Ristimäki, Taina Turpeenniemi-Hujanen & Outi Kuittinen. (2013) Increased expression of CIP2A in aggressive subtypes of B-cell lymphoma. Histopathology 63:3, pages 438-439.
Crossref
Crossref
Tuomo Rantanen, Tuuli Kauttu, Jonne Åkerla, Teemu Honkanen, Leena Krogerus, Jarmo Salo, Timo Paavonen & Niku Oksala. (2013) CIP2A expression and prognostic role in patients with esophageal adenocarcinoma. Medical Oncology 30:3.
Crossref
Crossref
Guangzhe Yu, Guohong Liu, Juan Dong & Yingyu Jin. (2013) Clinical implications of CIP2A protein expression in breast cancer. Medical Oncology 30:2.
Crossref
Crossref
FUXIN YI, WEIMIN NI, WEIXIAN LIU, JINYANG BAI & WENBIN LI. (2013) Expression and biological role of CIP2A in human astrocytoma. Molecular Medicine Reports 7:5, pages 1376-1380.
Crossref
Crossref
Danilo Perrotti & Paolo Neviani. (2013) Protein phosphatase 2A: a target for anticancer therapy. The Lancet Oncology 14:6, pages e229-e238.
Crossref
Crossref
Yijun Xue, Gengqing Wu, Xiaoning Wang, Xiaofeng Zou, Guoxi Zhang, Rihai Xiao, Yuanhu Yuan, Dazhi Long, Jun Yang, Yuting Wu, Hui Xu, Folin Liu & Min Liu. (2012) CIP2A is a predictor of survival and a novel therapeutic target in bladder urothelial cell carcinoma. Medical Oncology 30:1.
Crossref
Crossref
Anchit Khanna. (2013) Regulation of Cancerous inhibitor of PP2A (CIP2A) by small molecule inhibitor for c-Jun NH2-Terminal Kinases (JNKs), SP600125, in Human Fibrosarcoma (HT1080) cells . F1000Research 2, pages 174.
Crossref
Crossref
Yuanyuan Fang, Zhengtao Li, Xiuxia Wang & Shulan Zhang. (2012) CIP2A is overexpressed in human ovarian cancer and regulates cell proliferation and apoptosis. Tumor Biology 33:6, pages 2299-2306.
Crossref
Crossref