Expert Opinion on Drug Discovery, Volume 13, Issue 8 (2018)

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Expert Opinion on Drug Discovery, Volume 13, Issue 8 (2018)

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Editorial

Editorial
Challenges with biomarkers in cancer drug discovery and development
Ecaterina Ileana Dumbrava, Funda Meric-Bernstam & Timothy A. Yap
Pages: 685-690
Published online: 24 May 2018
First Page PreviewforChallenges with biomarkers in cancer drug discovery and development | Full Text | References | PDF (1,018.6 KB)
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Editorial
What’s happened over the last five years with high-throughput protein crystallization screening?
Yibin Lin
Pages: 691-695
Published online: 20 Apr 2018
First Page PreviewforWhat’s happened over the last five years with high-throughput protein crystallization screening? | Full Text | References | PDF (609.3 KB)
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Review

Review
Challenges with the precise prediction of ABC-transporter interactions for improved drug discovery
Donna A. Volpe & Hisham Qosa
Pages: 697-707
Published online: 09 Jul 2018
AbstractforChallenges with the precise prediction of ABC-transporter interactions for improved drug discovery | Full Text | References | PDF (1.1 MB)
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Review
Strategies for improving the specificity of siRNAs for enhanced therapeutic potential
Aditya Kiran Gatta, Raghu Chandrashekhar Hariharapura, Nayanabhirama Udupa, Meka Sreenivasa Reddy & Venkata Rao Josyula
Pages: 709-725
Published online: 14 Jun 2018
AbstractforStrategies for improving the specificity of siRNAs for enhanced therapeutic potential | Full Text | References | PDF (1.8 MB)
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Review
Developments with investigating descriptors for antimicrobial AApeptides and their derivatives
Olapeju Bolarinwa & Jianfeng Cai
Pages: 727-739
Published online: 22 Jun 2018
AbstractforDevelopments with investigating descriptors for antimicrobial AApeptides and their derivatives | Full Text | References | PDF (1.3 MB)
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Review
Recent advances in models for screening potential osteoporosis drugs
D. Merlotti, M. Materozzi, T. Picchioni, S. Bianciardi, M. Alessandri, R. Nuti & L. Gennari
Pages: 741-752
Published online: 05 Jun 2018
AbstractforRecent advances in models for screening potential osteoporosis drugs | Full Text | References | PDF (1.1 MB)
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Review
Introduction to biological complexity as a missing link in drug discovery
Gary A. Gintant & Christopher H. George
Pages: 753-763
Published online: 06 Jun 2018
AbstractforIntroduction to biological complexity as a missing link in drug discovery | Full Text | References | PDF (1.5 MB)
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Review
Proteomic approaches for novel systemic lupus erythematosus (SLE) drug discovery
Yaxi Li & Tianfu Wu
Pages: 765-777
Published online: 04 Jun 2018
AbstractforProteomic approaches for novel systemic lupus erythematosus (SLE) drug discovery | Full Text | References | PDF (1 MB)
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Drug Discovery Case History

Article
The preclinical discovery and development of cariprazine for the treatment of schizophrenia
Anna Wesołowska, Anna Partyka, Magdalena Jastrzębska-Więsek & Marcin Kołaczkowski
Pages: 779-790
Published online: 03 May 2018
AbstractforThe preclinical discovery and development of cariprazine for the treatment of schizophrenia | Full Text | References | PDF (927.4 KB)
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