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Volume 16, Issue 12

Expert Opinion on Drug Discovery

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Expert Opinion on Drug Discovery, Volume 16, Issue 12 (2021)

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Expert Opinion on Drug Discovery, Volume 16, Issue 12 (2021)

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Vol 19, 2024 Vol 18, 2023 Vol 17, 2022 Volume 16, 2021 Vol 15, 2020 Vol 14, 2019 Vol 13, 2018 Vol 12, 2017 Vol 11, 2016 Vol 10, 2015 Vol 9, 2014 Vol 8, 2013 Vol 7, 2012 Vol 6, 2011 Vol 5, 2010 Vol 4, 2009 Vol 3, 2008 Vol 2, 2007 Vol 1, 2006

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Editorial

How necessary are animal models for modern drug discovery?

Vijay K Singh & Thomas M Seed

Pages: 1391-1397

Published online: 03 Sep 2021

First Page PreviewforHow necessary are animal models for modern drug discovery? | Full Text | References | PDF (812.1 KB) | EPUB

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Editorial

How can we improve peptide drug discovery? Learning from the past

David J. Craik & Meng-Wei Kan

Pages: 1399-1402

Published online: 04 Aug 2021

First Page PreviewforHow can we improve peptide drug discovery? Learning from the past | Full Text | References | PDF (171.1 KB) | EPUB

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Drug Discovery Case History

Article

An overview of the preclinical discovery and development of bamlanivimab for the treatment of novel coronavirus infection (COVID-19): reasons for limited clinical use and lessons for the future

Marco Tuccori, Irma Convertino, Sara Ferraro, Giulia Valdiserra, Emiliano Cappello, Elisabetta Fini & Daniele Focosi

Pages: 1403-1414

Published online: 30 Jul 2021

AbstractforAn overview of the preclinical discovery and development of bamlanivimab for the treatment of novel coronavirus infection (COVID-19): reasons for limited clinical use and lessons for the future | Full Text | References | PDF (354 KB) | EPUB

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Perspective

Article

What is the gold standard model for Alzheimer’s disease drug discovery and development?

Ramón Cacabelos, Iván Carrera, Olaia Martínez-Iglesias, Natalia Cacabelos & Vinogran Naidoo

Pages: 1415-1440

Published online: 25 Aug 2021

AbstractforWhat is the gold standard model for Alzheimer’s disease drug discovery and development? | Full Text | References | PDF (2 MB) | EPUB

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Review

Article

Evolution of the drug-target residence time model

Robert A. Copeland

Pages: 1441-1451

Published online: 01 Jul 2021

AbstractforEvolution of the drug-target residence time model | Full Text | References | PDF (737.3 KB) | EPUB

708 Views
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An update on the importance of plasma protein binding in drug discovery and development

Li Di

Pages: 1453-1465

Published online: 17 Aug 2021

AbstractforAn update on the importance of plasma protein binding in drug discovery and development | Full Text | References | PDF (1 MB) | EPUB

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Recent advances in proteolytic stability for peptide, protein, and antibody drug discovery

Xianyin Lai, Jason Tang & Mohamed E.H. ElSayed

Pages: 1467-1482

Published online: 30 Jun 2021

AbstractforRecent advances in proteolytic stability for peptide, protein, and antibody drug discovery | Full Text | References | PDF (2 MB) | EPUB

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Article

Drug discovery strategies for novel leukotriene A4 hydrolase inhibitors

Till A Röhn, Shin Numao, Heike Otto, Christian Loesche & Gebhard Thoma

Pages: 1483-1495

Published online: 16 Jul 2021

AbstractforDrug discovery strategies for novel leukotriene A4 hydrolase inhibitors | Full Text | References | PDF (2 MB) | EPUB

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Glycyrrhetinic acid: a promising scaffold for the discovery of anticancer agents

Hidayat Hussain, Iftikhar Ali, Daijie Wang, Faruck L. Hakkim, Bernhard Westermann, Ishtiaq Ahmed, Ahmed M. Ashour, Amjad Khan, Amjad Hussain, Ivan R. Green & Syed Tasadaque Ali Shah

Pages: 1497-1516

Published online: 30 Jul 2021

AbstractforGlycyrrhetinic acid: a promising scaffold for the discovery of anticancer agents | Full Text | References | PDF (3.2 MB) | EPUB

4367 Views
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Open Access

Retinoic acid-related orphan receptor gamma t (RORγt) inverse agonists/antagonists for the treatment of inflammatory diseases – where are we presently?

Christian Gege

Pages: 1517-1535

Published online: 07 Jul 2021

AbstractforRetinoic acid-related orphan receptor gamma t (RORγt) inverse agonists/antagonists for the treatment of inflammatory diseases – where are we presently? | Full Text | References | PDF (2 MB) | EPUB

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Expert Opinion on Drug Discovery (Vol.16, Iss.12, 2021)

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