Future Medicinal Chemistry, Volume 2, Issue 5 (2010)

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Future Medicinal Chemistry, Volume 2, Issue 5 (2010)

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Special Focus Issue: Ion Channels: Key Therapeutic Targets - Foreword

Introduction
Welcome to “Ion Channels: Key Therapeutic Targets”
Gerald W Zamponi
Pages: 689-690
Published online: 12 May 2010
CitationforWelcome to “Ion Channels: Key Therapeutic Targets” | Full Text | References | PDF (372 KB)
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Editorial

Editorial
Renaissance of Ion Channel Research and Drug Discovery by Patch Clamp Automation
Niels Fertig & Cecilia Farre
Pages: 691-695
Published online: 12 May 2010
First Page PreviewforRenaissance of Ion Channel Research and Drug Discovery by Patch Clamp Automation | Full Text | References | PDF (1.5 MB)
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Editorial
Understanding Ion Channels Using Computational Approaches
Marcel J de Groot
Pages: 697-701
Published online: 12 May 2010
First Page PreviewforUnderstanding Ion Channels Using Computational Approaches | Full Text | References | PDF (416.1 KB)
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News & Analysis

News
News & Analysis
Pages: 703-706
Published online: 12 May 2010
First Page PreviewforNews & Analysis | Full Text | PDF (394.3 KB)
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Methodology

Article
Immunofluorescence-Based Assay to Identify Modulators of the Number of Plasma Membrane Kca3.1 Channels
Corina M Balut, Yajuan Gao, Cliff Luke & Daniel C Devor
Pages: 707-713
Published online: 12 May 2010
AbstractforImmunofluorescence-Based Assay to Identify Modulators of the Number of Plasma Membrane Kca3.1 Channels | Full Text | References | PDF (572.6 KB)
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Review

Review Article
Screening Technologies for Ion Channel Drug Discovery
Georg C Terstappen, Renza Roncarati, John Dunlop & Ravikumar Peri
Pages: 715-730
Published online: 12 May 2010
AbstractforScreening Technologies for Ion Channel Drug Discovery | Full Text | References | PDF (5.2 MB)
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Review Article
Natural Products and Ion Channel Pharmacology
Russell W Teichert & Baldomero M Olivera
Pages: 731-744
Published online: 12 May 2010
AbstractforNatural Products and Ion Channel Pharmacology | Full Text | References | PDF (2.5 MB)
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Review Article
K+ Channels as Therapeutic Targets in Oncology
Walter Stühmer & Luis A Pardo
Pages: 745-755
Published online: 12 May 2010
AbstractforK+ Channels as Therapeutic Targets in Oncology | Full Text | References | PDF (3.4 MB)
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Review Article
Small-Molecule Modulators of Inward Rectifier K+ Channels: Recent Advances and Future Possibilities
Gautam Bhave, Daniel Lonergan, Brian A Chauder & Jerod S Denton
Pages: 757-774
Published online: 12 May 2010
AbstractforSmall-Molecule Modulators of Inward Rectifier K+ Channels: Recent Advances and Future Possibilities | Full Text | References | PDF (3.7 MB)
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Review Article
Isoform-Selective Voltage-Gated Na+ Channel Modulators as Next-Generation Analgesics
Steve England & David Rawson
Pages: 775-790
Published online: 12 May 2010
AbstractforIsoform-Selective Voltage-Gated Na+ Channel Modulators as Next-Generation Analgesics | Full Text | References | PDF (3 MB)
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Review Article
Evolving Therapeutic Indications for N-Type Calcium Channel Blockers: From Chronic Pain to Alcohol Abuse
Francesco Belardetti
Pages: 791-802
Published online: 12 May 2010
AbstractforEvolving Therapeutic Indications for N-Type Calcium Channel Blockers: From Chronic Pain to Alcohol Abuse | Full Text | References | PDF (675.1 KB)
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Review Article
Ion Channel Blockers for the Treatment of Neuropathic Pain
Elena Colombo, Simona Francisconi, Laura Faravelli, Emanuela Izzo & Paolo Pevarello
Pages: 803-842
Published online: 12 May 2010
AbstractforIon Channel Blockers for the Treatment of Neuropathic Pain | Full Text | References | PDF (3 MB)
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Review Article
Recent Advances in the Biology and Medicinal Chemistry of Trpa1
Jason C Rech, William A Eckert, Michael P Maher, Tue Banke, Anindya Bhattacharya & Alan D Wickenden
Pages: 843-858
Published online: 12 May 2010
AbstractforRecent Advances in the Biology and Medicinal Chemistry of Trpa1 | Full Text | References | PDF (4.2 MB)
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Review Article
Insights into the Structure and Pharmacology of GABAA Receptors
Chris R J Carter, Janna L Kozuska & Susan M J Dunn
Pages: 859-875
Published online: 12 May 2010
AbstractforInsights into the Structure and Pharmacology of GABAA Receptors | Full Text | References | PDF (1 MB)
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Review Article
The Ampa Receptor as a Therapeutic Target: Current Perspectives and Emerging Possibilities
Ian R Mellor
Pages: 877-891
Published online: 12 May 2010
AbstractforThe Ampa Receptor as a Therapeutic Target: Current Perspectives and Emerging Possibilities | Full Text | References | PDF (2.6 MB)
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Erratum

Correction
Erratum
Page: 902
Published online: 22 Oct 2009
CitationforErratum | Full Text | PDF (139.2 KB)
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