Autophagy, Volume 15, Issue 3 (2019)

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Autophagy, Volume 15, Issue 3 (2019)

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Editor’s Corner

Editorial
Regulation of JMY’s actin nucleation activity by TTC5/STRAP and LC3 during autophagy
Xu Liu & Daniel J. Klionsky
Pages: 373-374
Published online: 06 Jan 2019
AbstractforRegulation of JMY’s actin nucleation activity by TTC5/STRAP and LC3 during autophagy | Full Text | References | PDF (355.1 KB) | EPUB
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Research Paper - Basic Science

Article
MITF-MIR211 axis is a novel autophagy amplifier system during cellular stress
Deniz Gulfem Ozturk, Muhammed Kocak, Arzu Akcay, Kubilay Kinoglu, Erdogan Kara, Yalcin Buyuk, Hilal Kazan & Devrim Gozuacik
Pages: 375-390
Published online: 16 Oct 2018
AbstractforMITF-MIR211 axis is a novel autophagy amplifier system during cellular stress | Full Text | References | PDF (3.1 MB) | EPUB | Supplemental
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Research Paper

Article
Identification of compound CA-5f as a novel late-stage autophagy inhibitor with potent anti-tumor effect against non-small cell lung cancer
Lu Zhang, PengFei Qiang, JingTing Yu, YiMing Miao, ZhiQiang Chen, Ju Qu, QianBing Zhao, Zhuo Chen, Yachao Liu, Xin Yao, Bin Liu, LiuQing Cui, HongJuan Jing & Gangchun Sun
Pages: 391-406
Published online: 06 Sep 2018
AbstractforIdentification of compound CA-5f as a novel late-stage autophagy inhibitor with potent anti-tumor effect against non-small cell lung cancer | Full Text | References | PDF (3.6 MB) | EPUB | Supplemental
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Article
Autophagy regulates glucose-mediated root meristem activity by modulating ROS production in Arabidopsis
Li Huang, Lu-Jun Yu, Xue Zhang, Biao Fan, Feng-Zhu Wang, Yang-Shuo Dai, Hua Qi, Ying Zhou, Li-Juan Xie & Shi Xiao
Pages: 407-422
Published online: 22 Sep 2018
AbstractforAutophagy regulates glucose-mediated root meristem activity by modulating ROS production in Arabidopsis | Full Text | References | PDF (2.9 MB) | EPUB | Supplemental
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Research Paper - Basic Science

Article
A nuclear membrane-derived structure associated with Atg8 is involved in the sequestration of selective cargo, the Cvt complex, during autophagosome formation in yeast
Misuzu Baba, Sachihiko Tomonaga, Masato Suzuki, Maeda Gen, Eigo Takeda, Akira Matsuura, Yoshiaki Kamada & Norio Baba
Pages: 423-437
Published online: 11 Oct 2018
AbstractforA nuclear membrane-derived structure associated with Atg8 is involved in the sequestration of selective cargo, the Cvt complex, during autophagosome formation in yeast | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
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Article
A cancer associated somatic mutation in LC3B attenuates its binding to E1-like ATG7 protein and subsequent lipidation
Gal Chaim Nuta, Yuval Gilad, Moran Gershoni, Arielle Sznajderman, Tomer Schlesinger, Shani Bialik, Miriam Eisenstein, Shmuel Pietrokovski & Adi Kimchi
Pages: 438-452
Published online: 08 Oct 2018
AbstractforA cancer associated somatic mutation in LC3B attenuates its binding to E1-like ATG7 protein and subsequent lipidation | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
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Research Paper

Article
CERKL regulates autophagy via the NAD-dependent deacetylase SIRT1
Xuebin Hu, Zhaojing Lu, Shanshan Yu, James Reilly, Fei Liu, Danna Jia, Yayun Qin, Shanshan Han, Xiliang Liu, Zhen Qu, Yuexia Lv, Jingzhen Li, Yuwen Huang, Tao Jiang, Haibo Jia, Qing Wang, Jingyu Liu, Xinhua Shu, Zhaohui Tang & Mugen Liu
Pages: 453-465
Published online: 25 Sep 2018
AbstractforCERKL regulates autophagy via the NAD-dependent deacetylase SIRT1 | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
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Article
RAB30 regulates PI4KB (phosphatidylinositol 4-kinase beta)-dependent autophagy against group A Streptococcus
Koji Nakajima, Takashi Nozawa, Atsuko Minowa-Nozawa, Hirotaka Toh, Shunsuke Yamada, Chihiro Aikawa & Ichiro Nakagawa
Pages: 466-477
Published online: 18 Oct 2018
AbstractforRAB30 regulates PI4KB (phosphatidylinositol 4-kinase beta)-dependent autophagy against group A Streptococcus | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
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Research Paper - Basic Science

Article
Mir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1
Yan Li, Dongmei Zhou, Yinghui Ren, Zimu Zhang, Xiangdong Guo, MingKun Ma, Zhenyi Xue, Jienv Lv, Hongkun Liu, Qing Xi, Long Jia, Lijuan Zhang, Ying Liu, Qi Zhang, Jun Yan, Yurong Da, Fei Gao, Jianbo Yue, Zhi Yao & Rongxin Zhang
Pages: 478-492
Published online: 22 Sep 2018
AbstractforMir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1 | Full Text | References | PDF (3.1 MB) | EPUB | Supplemental
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Article
Neuronal-targeted TFEB rescues dysfunction of the autophagy-lysosomal pathway and alleviates ischemic injury in permanent cerebral ischemia
Yueyang Liu, Xue Xue, Haotian Zhang, Xiaohang Che, Jing Luo, Ping Wang, Jiaoyan Xu, Zheng Xing, Linlin Yuan, Yinglu Liu, Xiaoxiao Fu, Dongmei Su, Shibo Sun, Haonan Zhang, Chunfu Wu & Jingyu Yang
Pages: 493-509
Published online: 18 Oct 2018
AbstractforNeuronal-targeted TFEB rescues dysfunction of the autophagy-lysosomal pathway and alleviates ischemic injury in permanent cerebral ischemia | Full Text | References | PDF (3.9 MB) | EPUB | Supplemental
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Research Paper

Article
PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis
Jun Araya, Kazuya Tsubouchi, Nahoko Sato, Saburo Ito, Shunsuke Minagawa, Hiromichi Hara, Yusuke Hosaka, Akihiro Ichikawa, Nayuta Saito, Tsukasa Kadota, Masahiro Yoshida, Yu Fujita, Hirofumi Utsumi, Kenji Kobayashi, Haruhiko Yanagisawa, Mitsuo Hashimoto, Hiroshi Wakui, Takeo Ishikawa, Takanori Numata, Yumi Kaneko, Hisatoshi Asano, Makoto Yamashita, Makoto Odaka, Toshiaki Morikawa, Stephen L Nishimura, Katsutoshi Nakayama & Kazuyoshi Kuwano
Pages: 510-526
Published online: 13 Oct 2018
AbstractforPRKN-regulated mitophagy and cellular senescence during COPD pathogenesis | Full Text | References | PDF (3.6 MB) | EPUB
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Research Paper - Basic Science

Article
A non-canonical autophagy-dependent role of the ATG16L1T300A variant in urothelial vesicular trafficking and uropathogenic Escherichia coli persistence
Caihong Wang, Kyle A. Bauckman, Adam S. B. Ross, Jane W. Symington, Marianne M. Ligon, Gael Scholtes, Akhil Kumar, Hao-Wei Chang, Joy Twentyman, Bisiayo E. Fashemi, Ramnik J. Xavier & Indira U. Mysorekar
Pages: 527-542
Published online: 08 Nov 2018
AbstractforA non-canonical autophagy-dependent role of the ATG16L1T300A variant in urothelial vesicular trafficking and uropathogenic Escherichia coli persistence | Full Text | References | PDF (3 MB) | EPUB | Supplemental
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Research Paper

Article
Transgenic expression of a ratiometric autophagy probe specifically in neurons enables the interrogation of brain autophagy in vivo
Ju-Hyun Lee, Mala V. Rao, Dun-Sheng Yang, Philip Stavrides, Eunju Im, Anna Pensalfini, Chunfeng Huo, Pallabi Sarkar, Tamotsu Yoshimori & Ralph A. Nixon
Pages: 543-557
Published online: 26 Oct 2018
AbstractforTransgenic expression of a ratiometric autophagy probe specifically in neurons enables the interrogation of brain autophagy in vivo | Full Text | References | PDF (3 MB) | EPUB
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Autophagic Punctum

Article Commentary
Methionine restriction for improving progeria: another autophagy-inducing anti-aging strategy?
Clea Bárcena, Carlos López-Otín & Guido Kroemer
Pages: 558-559
Published online: 18 Oct 2018
AbstractforMethionine restriction for improving progeria: another autophagy-inducing anti-aging strategy? | Full Text | References | PDF (466.5 KB) | EPUB
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