Autophagy, Volume 7, Issue 10 (2011)

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Autophagy, Volume 7, Issue 10 (2011)

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Editor's Corner

Editorial
For the last time, it is GFP-Atg8, not Atg8-GFP (and the same goes for LC3)
Daniel J Klionsky
Pages: 1093-1094
Published online: 01 Oct 2011
CitationforFor the last time, it is GFP-Atg8, not Atg8-GFP (and the same goes for LC3) | Full Text | References | PDF (380.1 KB)
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Autophagic Flux

Editorial
Highlights from this issue
Andriy Nemchenko
Pages: 1095-1097
Published online: 01 Oct 2011
First Page PreviewforHighlights from this issue | PDF (667.9 KB)
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Review

Review Article
GABARAPL1 (GEC1): Original or copycat?
Jaclyn Nicole Le Grand, Fatima Zahra Chakrama, Stéphanie Seguin-Py, Annick Fraichard, Régis Delage-Mourroux, Michèle Jouvenot & Michaël Boyer-Guittaut
Pages: 1098-1107
Published online: 01 Oct 2011
AbstractforGABARAPL1 (GEC1): Original or copycat? | PDF (2.6 MB)
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Translational Brief Report

Brief Report
ATRA-induced upregulation of Beclin 1 prolongs the life span of differentiated acute promyelocytic leukemia cells
Aurore Trocoli, Julie Mathieu, Muriel Priault, Josy Reiffers, Sylvie Souquère, Gérard Pierron, Françoise Besançon & Mojgan Djavaheri-Mergny
Pages: 1108-1114
Published online: 01 Oct 2011
AbstractforATRA-induced upregulation of Beclin 1 prolongs the life span of differentiated acute promyelocytic leukemia cells | Full Text | References | PDF (1.2 MB)
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Basic Research Paper

Article
Beclin 1-independent autophagy contributes to apoptosis in cortical neurons
Yulia Grishchuk, Vanessa Ginet, Anita C. Truttmann, Peter G.H. Clarke & Julien Puyal
Pages: 1115-1131
Published online: 01 Oct 2011
AbstractforBeclin 1-independent autophagy contributes to apoptosis in cortical neurons | PDF (3.7 MB) | Supplemental
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Article
PML-RARα enhances constitutive autophagic activity through inhibiting the Akt/mTOR pathway
Ying Huang, Jia-Kai Hou, Ting-Ting Chen, Xu-Yun Zhao, Zhao-Wen Yan, Jing Zhang, Jie Yang, Scott C. Kogan & Guo-Qiang Chen
Pages: 1132-1144
Published online: 01 Oct 2011
AbstractforPML-RARα enhances constitutive autophagic activity through inhibiting the Akt/mTOR pathway | Full Text | References | PDF (3.4 MB) | Supplemental
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Article
Identification and functional analysis of Joka2, a tobacco member of the family of selective autophagy cargo receptors
Katarzyna Zientara-Rytter, Jolanta Łukomska, Grzegorz Moniuszko, Rafał Gwozdecki, Przemysław Surowiecki, Małgorzata Lewandowska, Frantz Liszewska, Anna Wawrzyńska & Agnieszka Sirko
Pages: 1145-1158
Published online: 01 Oct 2011
AbstractforIdentification and functional analysis of Joka2, a tobacco member of the family of selective autophagy cargo receptors | Full Text | References | PDF (2.1 MB) | Supplemental
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Open Access
Article
Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis
Ying-Hong Shi, Zhen-Bin Ding, Jian Zhou, Bo Hui, Guo-Ming Shi, Ai-Wu Ke, Xiao-Ying Wang, Zhi Dai, Yuan-Fei Peng, Cheng-Yu Gu, Shuang-Jian Qiu & Jia Fan
Pages: 1159-1172
Published online: 01 Oct 2011
AbstractforTargeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis | PDF (3.2 MB) | Supplemental
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Article
Impaired autophagy due to constitutive mTOR activation sensitizes TSC2-null cells to cell death under stress
Shukie Ng, You-Tong Wu, Bo Chen, Jing Zhou & Han-Ming Shen
Pages: 1173-1186
Published online: 01 Oct 2011
AbstractforImpaired autophagy due to constitutive mTOR activation sensitizes TSC2-null cells to cell death under stress | PDF (6.6 MB)
  • 1948 Views
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Article
Involvement of mitophagy in oncogenic K-Ras-induced transformation
Overcoming a cellular energy deficit from glucose deficiency
June-Hyung Kim, Hee Young Kim, Young-Kyoung Lee, Young-Sil Yoon, Wei Guang Xu, Joon-Kee Yoon, Sung-E Choi, Young-Gyu Ko, Min-Jung Kim, Su-Jae Lee, Hee-Jung Wang & Gyesoon Yoon
Pages: 1187-1198
Published online: 01 Oct 2011
AbstractforInvolvement of mitophagy in oncogenic K-Ras-induced transformation | Full Text | References | PDF (2.4 MB) | Supplemental
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Article
cAMP induces autophagy via a novel pathway involving ERK, cyclin E and Beclin 1
Hege Ugland, Soheil Naderi, Andreas Brech, Philippe Collas & Heidi Kiil Blomhoff
Pages: 1199-1211
Published online: 01 Oct 2011
AbstractforcAMP induces autophagy via a novel pathway involving ERK, cyclin E and Beclin 1 | PDF (3 MB)
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Article
ULK1 inhibits the kinase activity of mTORC1 and cell proliferation
Chang Hwa Jung, Minchul Seo, Neil Michael Otto & Do-Hyung Kim
Pages: 1212-1221
Published online: 01 Oct 2011
AbstractforULK1 inhibits the kinase activity of mTORC1 and cell proliferation | Full Text | References | PDF (2.5 MB) | Supplemental
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Translational Research Paper

Article
Prognostic significance of Beclin 1 in intrahepatic cholangiocellular carcinoma
Li-Wei Dong, Yu-Jie Hou Hou, Ye-Xiong Tan, Liang Tang, Yu-Fei Pan, Min Wang & Hong-Yang Wang
Pages: 1222-1229
Published online: 01 Oct 2011
AbstractforPrognostic significance of Beclin 1 in intrahepatic cholangiocellular carcinoma | PDF (1.6 MB)
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Toolbox

Article
Spatiotemporally controlled initiation of Parkin-mediated mitophagy within single cells
Jin-Yi Yang & Wei Yuan Yang
Pages: 1230-1238
Published online: 01 Oct 2011
AbstractforSpatiotemporally controlled initiation of Parkin-mediated mitophagy within single cells | PDF (2.8 MB) | Supplemental
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Autophagic Punctum

Article Commentary
Cleaving Beclin 1 to suppress autophagy in chemotherapy-induced apoptosis
Hua Li, Peng Wang, Jian Yu & Lin Zhang
Pages: 1239-1241
Published online: 01 Oct 2011
AbstractforCleaving Beclin 1 to suppress autophagy in chemotherapy-induced apoptosis | Full Text | PDF (428.2 KB)
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Article Commentary
A critical role for UVRAG in apoptosis
Xiaocheng Yin, Lizhi Cao, Yanhui Peng, Yanfang Tan, Min Xie, Rui Kang, Kristen M. Livesey & Daolin Tang
Pages: 1242-1244
Published online: 01 Oct 2011
AbstractforA critical role for UVRAG in apoptosis | Full Text | PDF (439.7 KB)
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Article Commentary
A role for mitochondria in autophagy regulation
Martin Graef & Jodi Nunnari
Pages: 1245-1246
Published online: 01 Oct 2011
AbstractforA role for mitochondria in autophagy regulation | PDF (190.2 KB)
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Article Commentary
Antidepressants encounter autophagy in neural cells
Jürgen Zschocke & Theo Rein
Pages: 1247-1248
Published online: 01 Oct 2011
AbstractforAntidepressants encounter autophagy in neural cells | PDF (191.7 KB)
  • 587 Views
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Article Commentary
Membrane curvature response in autophagy
Livia Wilz, Weiliang Fan & Qing Zhong
Pages: 1249-1250
Published online: 01 Oct 2011
AbstractforMembrane curvature response in autophagy | Full Text | PDF (212.7 KB)
  • 703 Views
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Article Commentary
Mitochondrial elongation during autophagy
A stereotypical response to survive in difficult times
Ligia C. Gomes & Luca Scorrano
Pages: 1251-1253
Published online: 01 Oct 2011
AbstractforMitochondrial elongation during autophagy | Full Text | PDF (565.3 KB)
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Article Commentary
AMP-activated protein kinase modulates cardiac autophagy in diabetic cardiomyopathy
Zhonglin Xie, Chaoyong He & Ming-Hui Zou
Pages: 1254-1255
Published online: 01 Oct 2011
AbstractforAMP-activated protein kinase modulates cardiac autophagy in diabetic cardiomyopathy | Full Text | PDF (191.4 KB)
  • 1547 Views
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Article Commentary
Metabolic regulation by HMGB1-mediated autophagy and mitophagy
Rui Kang, Kristen M. Livesey, Herbert J. Zeh, III, Michael T. Loze & Daolin Tang
Pages: 1256-1258
Published online: 01 Oct 2011
AbstractforMetabolic regulation by HMGB1-mediated autophagy and mitophagy | PDF (528 KB)
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Article Commentary
Autophagy and proteotoxicity in cardiomyocytes
J. Scott Pattison & Jeffrey Robbins
Pages: 1259-1260
Published online: 01 Oct 2011
AbstractforAutophagy and proteotoxicity in cardiomyocytes | PDF (193 KB)
  • 466 Views
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Article Commentary
Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells
M. Danielle Bareford, Hossein A. Hamed, Yong Tang, Nichola Cruickshanks, Matthew E. Burow, Paul B. Fisher, Richard G. Moran, Kenneth P. Nephew, Steven Grant & Paul Dent
Pages: 1261-1262
Published online: 01 Oct 2011
AbstractforSorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells | Full Text | PDF (196.9 KB)
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Views and Commentaries

Autophagy anomalies in the diabetic myocardium
Kimberley M. Mellor, Melissa E. Reichelt & Lea M.D. Delbridge
Pages: 1263-1267
Published online: 01 Oct 2011
AbstractforAutophagy anomalies in the diabetic myocardium | PDF (534.6 KB)
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