Cancer Biology & Therapy, Volume 16, Issue 12 (2015)

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Cancer Biology & Therapy, Volume 16, Issue 12 (2015)

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Review

Anaplastic lymphoma kinase: Role in cancer and therapy perspective
Zhihong Zhao, Vivek Verma & Mutian Zhang
Pages: 1691-1701
Published online: 19 Jan 2016
AbstractforAnaplastic lymphoma kinase: Role in cancer and therapy perspective | Full Text | References | PDF (478.1 KB)
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Journal Club

Article
New bigenic mouse model increases the understanding of genetic synergism in the progression of prostate cancer
David J. Polman, Douglas K. Price & William D. Figg
Pages: 1702-1703
Published online: 19 Jan 2016
AbstractforNew bigenic mouse model increases the understanding of genetic synergism in the progression of prostate cancer | Full Text | References | PDF (53.2 KB)
  • 578 Views
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Bedside to Bench Report

Is the skin a sanctuary for breast cancer cells during treatment with anti-HER2 antibodies?
Vincenzo Graziano, Maria Teresa Scognamiglio, Marinella Zilli, Jamara Giampietro, Patrizia Vici, Clara Natoli & Antonino Grassadonia
Pages: 1704-1709
Published online: 19 Jan 2016
AbstractforIs the skin a sanctuary for breast cancer cells during treatment with anti-HER2 antibodies? | Full Text | References | PDF (514.3 KB)
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Regorafenib with a fluoropyrimidine for metastatic colorectal cancer after progression on multiple 5-FU-containing combination therapies and regorafenib monotherapy
Eric I. Marks, Carlyn Tan, Jun Zhang, Lanlan Zhou, Zhaohai Yang, Angelique Scicchitano & Wafik S. El-Deiry
Pages: 1710-1719
Published online: 19 Jan 2016
AbstractforRegorafenib with a fluoropyrimidine for metastatic colorectal cancer after progression on multiple 5-FU-containing combination therapies and regorafenib monotherapy | Full Text | References | PDF (1.1 MB)
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An exceptional overall survival using bevacizumab beyond progression in a patient with non-small cell lung cancer
Giandomenico Roviello, Edoardo Francini, Armando Perrella, Letizia Laera, Maria Antonietta Mazzei, Susanna Guerrini & Roberto Petrioli
Pages: 1720-1725
Published online: 19 Jan 2016
AbstractforAn exceptional overall survival using bevacizumab beyond progression in a patient with non-small cell lung cancer | Full Text | References | PDF (497.9 KB)
  • 605 Views
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Clinical Study

Article
Molecular profiling of 6,892 colorectal cancer samples suggests different possible treatment options specific to metastatic sites
Wafik S. El-Deiry, Namrata Vijayvergia, Joanne Xiu, Angelique Scicchitano, Bora Lim, Nelson S. Yee, Harold A. Harvey, Zoran Gatalica & Sandeep Reddy
Pages: 1726-1737
Published online: 19 Jan 2016
AbstractforMolecular profiling of 6,892 colorectal cancer samples suggests different possible treatment options specific to metastatic sites | Full Text | References | PDF (867.8 KB) | Supplemental
  • 4284 Views
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Article
Special AT-rich sequence binding protein 1 expression correlates with response to preoperative radiotherapy and clinical outcome in rectal cancer
Wen-Jian Meng, Surajit Pathak, Zhen-Yu Ding, Hong Zhang, Gunnar Adell, Birgitta Holmlund, Yuan Li, Zong-Guang Zhou & Xiao-Feng Sun
Pages: 1738-1745
Published online: 19 Jan 2016
AbstractforSpecial AT-rich sequence binding protein 1 expression correlates with response to preoperative radiotherapy and clinical outcome in rectal cancer | Full Text | References | PDF (504.8 KB) | Supplemental
  • 1041 Views
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Article
A phase II study of capecitabine plus cisplatin in metastatic triple-negative breast cancer patients pretreated with anthracyclines and taxanes
Qiao Li, Qing Li, Pin Zhang, Peng Yuan, Jiayu Wang, Fei Ma, Yang Luo, Ying Fan, Ruigang Cai & Binghe Xu
Pages: 1746-1753
Published online: 19 Jan 2016
AbstractforA phase II study of capecitabine plus cisplatin in metastatic triple-negative breast cancer patients pretreated with anthracyclines and taxanes | Full Text | References | PDF (239.9 KB)
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Research Paper

Article
microRNA-622 acts as a tumor suppressor in hepatocellular carcinoma
Wei-Hua Song, Xiao-Jun Feng, Shao-Juan Gong, Jian-Ming Chen, Shou-Mei Wang, Dong-Juan Xing, Ming-Hua Zhu, Shu-Hui Zhang & Ai-Min Xu
Pages: 1754-1763
Published online: 19 Jan 2016
AbstractformicroRNA-622 acts as a tumor suppressor in hepatocellular carcinoma | Full Text | References | PDF (1 MB) | Supplemental
  • 1280 Views
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Article
A bivalent recombinant immunotoxin with high potency against tumors with EGFR and EGFRvIII expression
Jie Meng, Yuanyi Liu, Shuying Gao, Stephen Lin, Xinbin Gu, Martin G Pomper, Paul C Wang & Liang Shan
Pages: 1764-1774
Published online: 19 Jan 2016
AbstractforA bivalent recombinant immunotoxin with high potency against tumors with EGFR and EGFRvIII expression | Full Text | References | PDF (619.7 KB)
  • 1260 Views
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Article
CXCL4 mediates tumor regrowth after chemotherapy by suppression of antitumor immunity
Yang Zhang, Jing Gao, Xia Wang, Shaorong Deng, Hao Ye, Wen Guan, Mingyuan Wu, Shunying Zhu, Yan Yu & Wei Han
Pages: 1775-1783
Published online: 19 Jan 2016
AbstractforCXCL4 mediates tumor regrowth after chemotherapy by suppression of antitumor immunity | Full Text | References | PDF (885 KB) | Supplemental
  • 1649 Views
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Article
Synergistic anti-leukemic interactions between panobinostat and MK-1775 in acute myeloid leukemia ex vivo
Wenxiu Qi, Wenbo Zhang, Holly Edwards, Roland Chu, Gerard J Madlambayan, Jeffrey W Taub, Zhihong Wang, Yue Wang, Chunhuai Li, Hai Lin & Yubin Ge
Pages: 1784-1793
Published online: 19 Jan 2016
AbstractforSynergistic anti-leukemic interactions between panobinostat and MK-1775 in acute myeloid leukemia ex vivo | Full Text | References | PDF (1 MB) | Supplemental
  • 1438 Views
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Article
Reversal effects of Raloxifene on paclitaxel resistance in 2 MDR breast cancer cells
Liang Xu, Jingyu Lei, Donghai Jiang, Lin Zhou, Shu Wang & Weimin Fan
Pages: 1794-1801
Published online: 19 Jan 2016
AbstractforReversal effects of Raloxifene on paclitaxel resistance in 2 MDR breast cancer cells | Full Text | References | PDF (764.3 KB)
  • 924 Views
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Article
Thrombin inhibition and cyclophosphamide synergistically block tumor progression and metastasis
Eric T Alexander, Allyson R Minton, Candace S Hayes, Ashley Goss, Joanne Van Ryn & Susan K Gilmour
Pages: 1802-1811
Published online: 19 Jan 2016
AbstractforThrombin inhibition and cyclophosphamide synergistically block tumor progression and metastasis | Full Text | References | PDF (473.3 KB)
  • 1572 Views
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Article
Development of a radiofrequency ablation platform in a clinically relevant murine model of hepatocellular cancer
Xiaoqiang Qi, Guangfu Li, Dai Liu, Anjan Motamarry, Xiangwei Huang, A. Marissa Wolfe, Kristi L. Helke, Dieter Haemmerich, Kevin F Staveley-O'Carroll & Eric T Kimchi
Pages: 1812-1819
Published online: 19 Jan 2016
AbstractforDevelopment of a radiofrequency ablation platform in a clinically relevant murine model of hepatocellular cancer | Full Text | References | PDF (812.8 KB)
  • 1012 Views
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Research Papers

Article
Antiproliferative and proapoptotic effects of a pyrrole containing arylthioindole in human Jurkat leukemia cell line and multidrug-resistant Jurkat/A4 cells
Alex A Philchenkov, Michael P Zavelevich, Volodymyr P Tryndyak, Ludmila M Kuiava, Dmitry Yu Blokhin, Koh Miura, Romano Silvestri & Igor P Pogribny
Pages: 1820-1829
Published online: 19 Jan 2016
AbstractforAntiproliferative and proapoptotic effects of a pyrrole containing arylthioindole in human Jurkat leukemia cell line and multidrug-resistant Jurkat/A4 cells | Full Text | References | PDF (719.2 KB) | Supplemental
  • 978 Views
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Research Paper

Article
Sphingosine kinase inhibitors decrease viability and induce cell death in natural killer-large granular lymphocyte leukemia
Francis R LeBlanc, Xin Liu, Jeremy Hengst, Todd Fox, Valerie Calvert, Emanuel F Petricoin III, Jong Yun, David J Feith & Thomas P Loughran Jr
Pages: 1830-1840
Published online: 19 Jan 2016
AbstractforSphingosine kinase inhibitors decrease viability and induce cell death in natural killer-large granular lymphocyte leukemia | Full Text | References | PDF (777.1 KB) | Supplemental
  • 1410 Views
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