Molecular and Cellular Biology, Volume 24, Issue 22 (2004)

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Molecular and Cellular Biology, Volume 24, Issue 22 (2004)

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Cell Growth and Development

Article
Proteasome Inhibitor PS-341 Induces Apoptosis through Induction of Endoplasmic Reticulum Stress-Reactive Oxygen Species in Head and Neck Squamous Cell Carcinoma Cells
Andrew Fribley, Qinghua Zeng & Cun-Yu Wang
Pages: 9695-9704
Published online: 27 Mar 2023
AbstractforProteasome Inhibitor PS-341 Induces Apoptosis through Induction of Endoplasmic Reticulum Stress-Reactive Oxygen Species in Head and Neck Squamous Cell Carcinoma Cells | Full Text | References | PDF (428.5 KB)
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Article
Retinoid X Receptor Regulates Nur77/Thyroid Hormone Receptor 3-Dependent Apoptosis by Modulating Its Nuclear Export and Mitochondrial Targeting
Xihua Cao, Wen Liu, Feng Lin, Hui Li, Siva Kumar Kolluri, Bingzhen Lin, Young-hoon Han, Marcia I. Dawson & Xiao-kun Zhang
Pages: 9705-9725
Published online: 27 Mar 2023
AbstractforRetinoid X Receptor Regulates Nur77/Thyroid Hormone Receptor 3-Dependent Apoptosis by Modulating Its Nuclear Export and Mitochondrial Targeting | Full Text | References | PDF (2.4 MB)
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Article
Involvement of Insulin Receptor Substrate 2 in Mammary Tumor Metastasis
Julie A. Nagle, Zhefu Ma, Maura A. Byrne, Morris F. White & Leslie M. Shaw
Pages: 9726-9735
Published online: 27 Mar 2023
AbstractforInvolvement of Insulin Receptor Substrate 2 in Mammary Tumor Metastasis | Full Text | References | PDF (1.1 MB)
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Article
Essential Requirement of CCAAT/Enhancer Binding Proteins in Embryogenesis
Valérie Bégay, Jeske Smink & Achim Leutz
Pages: 9744-9751
Published online: 27 Mar 2023
AbstractforEssential Requirement of CCAAT/Enhancer Binding Proteins in Embryogenesis | Full Text | References | PDF (852.4 KB)
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Article
The TBC (Tre-2/Bub2/Cdc16) Domain Protein TRE17 Regulates Plasma Membrane-Endosomal Trafficking through Activation of Arf6
Lenka Martinu, Jeffrey M. Masuda-Robens, Sarah E. Robertson, Lorraine C. Santy, James E. Casanova & Margaret M. Chou
Pages: 9752-9762
Published online: 27 Mar 2023
AbstractforThe TBC (Tre-2/Bub2/Cdc16) Domain Protein TRE17 Regulates Plasma Membrane-Endosomal Trafficking through Activation of Arf6 | Full Text | References | PDF (588.9 KB) | Supplemental
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Article
Calcium Binding of ARC Mediates Regulation of Caspase 8 and Cell Death
Dong-Gyu Jo, Joon-Il Jun, Jae-Woong Chang, Yeon-Mi Hong, Sungmin Song, Dong-Hyung Cho, Sang Mi Shim, Ho-June Lee, Chunghee Cho, Do Han Kim & Yong-Keun Jung
Pages: 9763-9770
Published online: 27 Mar 2023
AbstractforCalcium Binding of ARC Mediates Regulation of Caspase 8 and Cell Death | Full Text | References | PDF (527 KB) | Supplemental
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Article
Amino Acid Signaling in Yeast: Casein Kinase I and the Ssy5 Endoprotease Are Key Determinants of Endoproteolytic Activation of the Membrane-Bound Stp1 Transcription Factor
Fadi Abdel-Sater, Mohamed El Bakkoury, Antonio Urrestarazu, Stephan Vissers & Bruno André
Pages: 9771-9785
Published online: 27 Mar 2023
AbstractforAmino Acid Signaling in Yeast: Casein Kinase I and the Ssy5 Endoprotease Are Key Determinants of Endoproteolytic Activation of the Membrane-Bound Stp1 Transcription Factor | Full Text | References | PDF (598.9 KB)
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Article
ETO/MTG8 Is an Inhibitor of C/EBPβ Activity and a Regulator of Early Adipogenesis
Justin J. Rochford, Robert K. Semple, Matthias Laudes, Keith B. Boyle, Constantinos Christodoulides, Claire Mulligan, Christopher J. Lelliott, Sven Schinner, Dirk Hadaschik, Meera Mahadevan, Jaswinder K. Sethi, Antonio Vidal-Puig & Stephen O'Rahilly
Pages: 9863-9872
Published online: 27 Mar 2023
AbstractforETO/MTG8 Is an Inhibitor of C/EBPβ Activity and a Regulator of Early Adipogenesis | Full Text | References | PDF (568.7 KB)
  • 51 Views
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Article
Novel Functional Dissection of the Localization-Specific Roles of Budding Yeast Polo Kinase Cdc5p
Jung-Eun Park, Chong J. Park, Krisada Sakchaisri, Tatiana Karpova, Satoshi Asano, James McNally, Yangil Sunwoo, Sun-Hee Leem & Kyung S. Lee
Pages: 9873-9886
Published online: 27 Mar 2023
AbstractforNovel Functional Dissection of the Localization-Specific Roles of Budding Yeast Polo Kinase Cdc5p | Full Text | References | PDF (806.8 KB)
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Article
Inactivation of the Mgat1 Gene in Oocytes Impairs Oogenesis, but Embryos Lacking Complex and Hybrid N-Glycans Develop and Implant
Shaolin Shi, Suzannah A. Williams, Antti Seppo, Henry Kurniawan, Wei Chen, Zhengyi Ye, Jamey D. Marth & Pamela Stanley
Pages: 9920-9929
Published online: 27 Mar 2023
AbstractforInactivation of the Mgat1 Gene in Oocytes Impairs Oogenesis, but Embryos Lacking Complex and Hybrid N-Glycans Develop and Implant | Full Text | References | PDF (803.5 KB)
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Article
Inducible Gene Trapping with Drug-Selectable Markers and Cre/loxP To Identify Developmentally Regulated Genes
You-Tzung Chen, Pentao Liu & Allan Bradley
Pages: 9930-9941
Published online: 27 Mar 2023
AbstractforInducible Gene Trapping with Drug-Selectable Markers and Cre/loxP To Identify Developmentally Regulated Genes | Full Text | References | PDF (917.3 KB)
  • 6 Views
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Article
Telomeric DNA in ALT Cells Is Characterized by Free Telomeric Circles and Heterogeneous t-Loops
Anthony J. Cesare & Jack D. Griffith
Pages: 9948-9957
Published online: 27 Mar 2023
AbstractforTelomeric DNA in ALT Cells Is Characterized by Free Telomeric Circles and Heterogeneous t-Loops | Full Text | References | PDF (564.8 KB)
  • 87 Views
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Article
NAD+ Modulates p53 DNA Binding Specificity and Function
Kevin G. McLure, Masatoshi Takagi & Michael B. Kastan
Pages: 9958-9967
Published online: 27 Mar 2023
AbstractforNAD+ Modulates p53 DNA Binding Specificity and Function | Full Text | References | PDF (332.2 KB)
  • 25 Views
  • 65 CrossRef citations
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Article
Xenopus Cds1 Is Regulated by DNA-Dependent Protein Kinase and ATR during the Cell Cycle Checkpoint Response to Double-Stranded DNA Ends
Troy D. McSherry & Paul R. Mueller
Pages: 9968-9985
Published online: 27 Mar 2023
AbstractforXenopus Cds1 Is Regulated by DNA-Dependent Protein Kinase and ATR during the Cell Cycle Checkpoint Response to Double-Stranded DNA Ends | Full Text | References | PDF (740.5 KB)
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Article
Mechanism of B-Cell Receptor-Induced Phosphorylation and Activation of Phospholipase C-γ2
Yeun Ju Kim, Fujio Sekiya, Benoit Poulin, Yun Soo Bae & Sue Goo Rhee
Pages: 9986-9999
Published online: 27 Mar 2023
AbstractforMechanism of B-Cell Receptor-Induced Phosphorylation and Activation of Phospholipase C-γ2 | Full Text | References | PDF (543.5 KB)
  • 156 Views
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Article
Extracellular Signal-Regulated Kinase 1c (ERK1c), a Novel 42-Kilodalton ERK, Demonstrates Unique Modes of Regulation, Localization, and Function
Daniel M. Aebersold, Yoav D. Shaul, Yuval Yung, Nirit Yarom, Zhong Yao, Tamar Hanoch & Rony Seger
Pages: 10000-10015
Published online: 27 Mar 2023
AbstractforExtracellular Signal-Regulated Kinase 1c (ERK1c), a Novel 42-Kilodalton ERK, Demonstrates Unique Modes of Regulation, Localization, and Function | Full Text | References | PDF (756.6 KB) | Supplemental
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
Neonatal Lethality of LGR5 Null Mice Is Associated with Ankyloglossia and Gastrointestinal Distension
Hiroki Morita, Sabine Mazerbourg, Donna M. Bouley, Ching-Wei Luo, Kazuhiro Kawamura, Yoshimitsu Kuwabara, Helene Baribault, Hui Tian & Aaron J. W. Hsueh
Pages: 9736-9743
Published online: 27 Mar 2023
AbstractforNeonatal Lethality of LGR5 Null Mice Is Associated with Ankyloglossia and Gastrointestinal Distension | Full Text | References | PDF (1 MB)
  • 84 Views
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Article
Neuroprotective Role of the Reaper-Related Serine Protease HtrA2/Omi Revealed by Targeted Deletion in Mice
L. Miguel Martins, Alastair Morrison, Kristina Klupsch, Valentina Fedele, Nicoleta Moisoi, Peter Teismann, Alejandro Abuin, Evelyn Grau, Martin Geppert, George P. Livi, Caretha L. Creasy, Alison Martin, Iain Hargreaves, Simon J. Heales, Hitoshi Okada, Sebastian Brandner, Jörg B. Schulz, Tak Mak & Julian Downward
Pages: 9848-9862
Published online: 27 Mar 2023
AbstractforNeuroprotective Role of the Reaper-Related Serine Protease HtrA2/Omi Revealed by Targeted Deletion in Mice | Full Text | References | PDF (795.5 KB)
  • 43 Views
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Article
The Wt1+/R394W Mouse Displays Glomerulosclerosis and Early-Onset Renal Failure Characteristic of Human Denys-Drash Syndrome
Fei Gao, Sourindra Maiti, Guizhi Sun, Nelson G. Ordonez, Malini Udtha, Jian Min Deng, Richard R. Behringer & Vicki Huff
Pages: 9899-9910
Published online: 27 Mar 2023
AbstractforThe Wt1+/R394W Mouse Displays Glomerulosclerosis and Early-Onset Renal Failure Characteristic of Human Denys-Drash Syndrome | Full Text | References | PDF (1.6 MB)
  • 63 Views
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Article
Carbonic Anhydrase III Is Not Required in the Mouse for Normal Growth, Development, and Life Span
Geumsoo Kim, Tae-Hoon Lee, Petra Wetzel, Cornelia Geers, Mary Ann Robinson, Timothy G. Myers, Jennie W. Owens, Nancy B. Wehr, Michael W. Eckhaus, Gerolf Gros, Anthony Wynshaw-Boris & Rodney L. Levine
Pages: 9942-9947
Published online: 27 Mar 2023
AbstractforCarbonic Anhydrase III Is Not Required in the Mouse for Normal Growth, Development, and Life Span | Full Text | References | PDF (132.6 KB)
  • 30 Views
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Dna Dynamics and Chromosome Structure

Article
Kinetochore Targeting of Fission Yeast Mad and Bub Proteins Is Essential for Spindle Checkpoint Function but Not for All Chromosome Segregation Roles of Bub1p
Vincent Vanoosthuyse, Rebekka Valsdottir, Jean-Paul Javerzat & Kevin G. Hardwick
Pages: 9786-9801
Published online: 27 Mar 2023
AbstractforKinetochore Targeting of Fission Yeast Mad and Bub Proteins Is Essential for Spindle Checkpoint Function but Not for All Chromosome Segregation Roles of Bub1p | Full Text | References | PDF (1,013.2 KB) | Supplemental
  • 12 Views
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Article
Tankyrase Polymerization Is Controlled by Its Sterile Alpha Motif and Poly(ADP-Ribose) Polymerase Domains
Manu De Rycker & Carolyn M. Price
Pages: 9802-9812
Published online: 27 Mar 2023
AbstractforTankyrase Polymerization Is Controlled by Its Sterile Alpha Motif and Poly(ADP-Ribose) Polymerase Domains | Full Text | References | PDF (695.4 KB)
  • 28 Views
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Article
Biochemical Interactions between Proteins and mat1 cis-Acting Sequences Required for Imprinting in Fission Yeast
Bum-Soo Lee, Shiv I. S. Grewal & Amar J. S. Klar
Pages: 9813-9822
Published online: 27 Mar 2023
AbstractforBiochemical Interactions between Proteins and mat1 cis-Acting Sequences Required for Imprinting in Fission Yeast | Full Text | References | PDF (499.1 KB)
  • 8 Views
  • 26 CrossRef citations
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Article
Architectural Role of Mitochondrial Transcription Factor A in Maintenance of Human Mitochondrial DNA
Tomotake Kanki, Kippei Ohgaki, Martina Gaspari, Claes M. Gustafsson, Atsushi Fukuoh, Narie Sasaki, Naotaka Hamasaki & Dongchon Kang
Pages: 9823-9834
Published online: 27 Mar 2023
AbstractforArchitectural Role of Mitochondrial Transcription Factor A in Maintenance of Human Mitochondrial DNA | Full Text | References | PDF (726.6 KB)
  • 99 Views
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Article
Ty1 Mobilizes Subtelomeric Y′ Elements in Telomerase-Negative Saccharomyces cerevisiae Survivors
Patrick H. Maxwell, Candice Coombes, Alison E. Kenny, Joseph F. Lawler, Jef D. Boeke & M. Joan Curcio
Pages: 9887-9898
Published online: 27 Mar 2023
AbstractforTy1 Mobilizes Subtelomeric Y′ Elements in Telomerase-Negative Saccharomyces cerevisiae Survivors | Full Text | References | PDF (614.5 KB)
  • 12 Views
  • 35 CrossRef citations
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Article
Requirement of the Mre11 Complex and Exonuclease 1 for Activation of the Mec1 Signaling Pathway
Daisuke Nakada, Yukinori Hirano & Katsunori Sugimoto
Pages: 10016-10025
Published online: 27 Mar 2023
AbstractforRequirement of the Mre11 Complex and Exonuclease 1 for Activation of the Mec1 Signaling Pathway | Full Text | References | PDF (384.4 KB)
  • 33 Views
  • 95 CrossRef citations
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Article
Global Chromatin Structure of 45,000 Base Pairs of Chromosome III in a- and α-Cell Yeast and during Mating-Type Switching
Sevinc Ercan & Robert T. Simpson
Pages: 10026-10035
Published online: 27 Mar 2023
AbstractforGlobal Chromatin Structure of 45,000 Base Pairs of Chromosome III in a- and α-Cell Yeast and during Mating-Type Switching | Full Text | References | PDF (409.5 KB)
  • 2 Views
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Article
Functional Role of Extranucleosomal DNA and the Entry Site of the Nucleosome in Chromatin Remodeling by ISW2
Martin Zofall, Jim Persinger & Blaine Bartholomew
Pages: 10047-10057
Published online: 27 Mar 2023
AbstractforFunctional Role of Extranucleosomal DNA and the Entry Site of the Nucleosome in Chromatin Remodeling by ISW2 | Full Text | References | PDF (476.1 KB)
  • 26 Views
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Transcriptional Regulation

Article
Differential Regulation of Hand1 Homodimer and Hand1-E12 Heterodimer Activity by the Cofactor FHL2
Alison A. Hill & Paul R. Riley
Pages: 9835-9847
Published online: 27 Mar 2023
AbstractforDifferential Regulation of Hand1 Homodimer and Hand1-E12 Heterodimer Activity by the Cofactor FHL2 | Full Text | References | PDF (727.1 KB)
  • 8 Views
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Article
FoxO3a and BCR-ABL Regulate cyclin D2 Transcription through a STAT5/BCL6-Dependent Mechanism
Silvia Fernández de Mattos, Abdelkader Essafi, Inês Soeiro, Alexandra M. Pietersen, Kim U. Birkenkamp, Corinne S. Edwards, Anthony Martino, Brad H. Nelson, Julia M. Francis, Marius C. Jones, Jan J. Brosens, Paul J. Coffer & Eric W.-F. Lam
Pages: 10058-10071
Published online: 27 Mar 2023
AbstractforFoxO3a and BCR-ABL Regulate cyclin D2 Transcription through a STAT5/BCL6-Dependent Mechanism | Full Text | References | PDF (617.8 KB)
  • 29 Views
  • 134 CrossRef citations
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Article
NC2α Interacts with BTAF1 and Stimulates Its ATP-Dependent Association with TATA-Binding Protein
Marcin P. Klejman, Lloyd A. Pereira, Hester J. T. van Zeeburg, Siv Gilfillan, Michael Meisterernst & H. T. Marc Timmers
Pages: 10072-10082
Published online: 27 Mar 2023
AbstractforNC2α Interacts with BTAF1 and Stimulates Its ATP-Dependent Association with TATA-Binding Protein | Full Text | References | PDF (408.1 KB)
  • 50 Views
  • 23 CrossRef citations
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Article
Interferon Regulatory Factor 1 Binding to p300 Stimulates DNA-Dependent Acetylation of p53
David Dornan, Mirjam Eckert, Maura Wallace, Harumi Shimizu, Eleanor Ramsay, Ted R. Hupp & Kathryn L. Ball
Pages: 10083-10098
Published online: 27 Mar 2023
AbstractforInterferon Regulatory Factor 1 Binding to p300 Stimulates DNA-Dependent Acetylation of p53 | Full Text | References | PDF (828.3 KB)
  • 44 Views
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Gene Expression

Article
In Vivo Requirement of the RNA Polymerase II Elongation Factor Elongin A for Proper Gene Expression and Development
Mark Gerber, Joel C. Eissenberg, Stephanie Kong, Kristen Tenney, Joan Weliky Conaway, Ronald C. Conaway & Ali Shilatifard
Pages: 9911-9919
Published online: 27 Mar 2023
AbstractforIn Vivo Requirement of the RNA Polymerase II Elongation Factor Elongin A for Proper Gene Expression and Development | Full Text | References | PDF (1.2 MB)
  • 24 Views
  • 29 CrossRef citations
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Article
Regulation of Cell Cycle-Specific Gene Expression through Cyclin-Dependent Kinase-Mediated Phosphorylation of the Forkhead Transcription Factor Fkh2p
Aline Pic-Taylor, Zoulfia Darieva, Brian A. Morgan & Andrew D. Sharrocks
Pages: 10036-10046
Published online: 27 Mar 2023
AbstractforRegulation of Cell Cycle-Specific Gene Expression through Cyclin-Dependent Kinase-Mediated Phosphorylation of the Forkhead Transcription Factor Fkh2p | Full Text | References | PDF (462 KB)
  • 25 Views
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Errata

Correction
Characterization of Karyopherin Cargoes Reveals Unique Mechanisms of Kap121p-Mediated Nuclear Import
Page: 10099
Published online: 27 Mar 2023
CitationforCharacterization of Karyopherin Cargoes Reveals Unique Mechanisms of Kap121p-Mediated Nuclear Import | Full Text | PDF (17 KB)
  • 96 Views
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