Molecular and Cellular Biology, Volume 27, Issue 21 (2007)

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Molecular and Cellular Biology, Volume 27, Issue 21 (2007)

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Articles

Article
Phosphorylation of TPL-2 on Serine 400 Is Essential for Lipopolysaccharide Activation of Extracellular Signal-Regulated Kinase in Macrophages
M. J. Robinson, S. Beinke, A. Kouroumalis, P. N. Tsichlis & S. C. Ley
Pages: 7355-7364
Published online: 27 Mar 2023
AbstractforPhosphorylation of TPL-2 on Serine 400 Is Essential for Lipopolysaccharide Activation of Extracellular Signal-Regulated Kinase in Macrophages | Full Text | References | PDF (425.3 KB)
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Article
An Intronic Locus Control Region Plays an Essential Role in the Establishment of an Autonomous Hepatic Chromatin Domain for the Human Vitamin D-Binding Protein Gene
Tomoko Hiroki, Stephen A. Liebhaber & Nancy E. Cooke
Pages: 7365-7380
Published online: 27 Mar 2023
AbstractforAn Intronic Locus Control Region Plays an Essential Role in the Establishment of an Autonomous Hepatic Chromatin Domain for the Human Vitamin D-Binding Protein Gene | Full Text | References | PDF (758.4 KB)
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Article
Hypoxia-Inducible Factor 1 and Dysregulated c-Myc Cooperatively Induce Vascular Endothelial Growth Factor and Metabolic Switches Hexokinase 2 and Pyruvate Dehydrogenase Kinase 1
Jung-whan Kim, Ping Gao, Yen-Chun Liu, Gregg L. Semenza & Chi V. Dang
Pages: 7381-7393
Published online: 27 Mar 2023
AbstractforHypoxia-Inducible Factor 1 and Dysregulated c-Myc Cooperatively Induce Vascular Endothelial Growth Factor and Metabolic Switches Hexokinase 2 and Pyruvate Dehydrogenase Kinase 1 | Full Text | References | PDF (626.9 KB) | Supplemental
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Article
FADD Negatively Regulates Lipopolysaccharide Signaling by Impairing Interleukin-1 Receptor-Associated Kinase 1-MyD88 Interaction
Rachel Zhande, Shauna M. Dauphinee, James A. Thomas, Masahiro Yamamoto, Shizuo Akira & Aly Karsan
Pages: 7394-7404
Published online: 27 Mar 2023
AbstractforFADD Negatively Regulates Lipopolysaccharide Signaling by Impairing Interleukin-1 Receptor-Associated Kinase 1-MyD88 Interaction | Full Text | References | PDF (581.9 KB)
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Article
Inhibition of Mammalian Target of Rapamycin Induces Phosphatidylinositol 3-Kinase-Dependent and Mnk-Mediated Eukaryotic Translation Initiation Factor 4E Phosphorylation
Xuerong Wang, Ping Yue, Chi-Bun Chan, Keqiang Ye, Takeshi Ueda, Rie Watanabe-Fukunaga, Rikiro Fukunaga, Haian Fu, Fadlo R. Khuri & Shi-Yong Sun
Pages: 7405-7413
Published online: 27 Mar 2023
AbstractforInhibition of Mammalian Target of Rapamycin Induces Phosphatidylinositol 3-Kinase-Dependent and Mnk-Mediated Eukaryotic Translation Initiation Factor 4E Phosphorylation | Full Text | References | PDF (366.7 KB) | Supplemental
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Article
Heme Levels Switch the Function of Hap1 of Saccharomyces cerevisiae between Transcriptional Activator and Transcriptional Repressor
Mark J. Hickman & Fred Winston
Pages: 7414-7424
Published online: 27 Mar 2023
AbstractforHeme Levels Switch the Function of Hap1 of Saccharomyces cerevisiae between Transcriptional Activator and Transcriptional Repressor | Full Text | References | PDF (1.1 MB) | Supplemental
  • 88 Views
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Article
The Pu.1 Locus Is Differentially Regulated at the Level of Chromatin Structure and Noncoding Transcription by Alternate Mechanisms at Distinct Developmental Stages of Hematopoiesis
Maarten Hoogenkamp, Hanna Krysinska, Richard Ingram, Gang Huang, Rachael Barlow, Deborah Clarke, Alexander Ebralidze, Pu Zhang, Hiromi Tagoh, Peter N. Cockerill, Daniel G. Tenen & Constanze Bonifer
Pages: 7425-7438
Published online: 27 Mar 2023
AbstractforThe Pu.1 Locus Is Differentially Regulated at the Level of Chromatin Structure and Noncoding Transcription by Alternate Mechanisms at Distinct Developmental Stages of Hematopoiesis | Full Text | References | PDF (1.7 MB)
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Article
The Human F-Box DNA Helicase FBH1 Faces Saccharomyces cerevisiae Srs2 and Postreplication Repair Pathway Roles
Irene Chiolo, Marco Saponaro, Anastasia Baryshnikova, Jeong-Hoon Kim, Yeon-Soo Seo & Giordano Liberi
Pages: 7439-7450
Published online: 27 Mar 2023
AbstractforThe Human F-Box DNA Helicase FBH1 Faces Saccharomyces cerevisiae Srs2 and Postreplication Repair Pathway Roles | Full Text | References | PDF (1.3 MB)
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Article
IκB Kinase β Phosphorylates the K63 Deubiquitinase A20 To Cause Feedback Inhibition of the NF-κB Pathway
Jessica E. Hutti, Benjamin E. Turk, John M. Asara, Averil Ma, Lewis C. Cantley & Derek W. Abbott
Pages: 7451-7461
Published online: 27 Mar 2023
AbstractforIκB Kinase β Phosphorylates the K63 Deubiquitinase A20 To Cause Feedback Inhibition of the NF-κB Pathway | Full Text | References | PDF (535.4 KB)
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Article
Acetylation-Induced Transcription Is Required for Active DNA Demethylation in Methylation-Silenced Genes
Ana C. D'Alessio, Ian C. G. Weaver & Moshe Szyf
Pages: 7462-7474
Published online: 27 Mar 2023
AbstractforAcetylation-Induced Transcription Is Required for Active DNA Demethylation in Methylation-Silenced Genes | Full Text | References | PDF (745.5 KB)
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Article
The DNA Binding and Catalytic Domains of Poly(ADP-Ribose) Polymerase 1 Cooperate in the Regulation of Chromatin Structure and Transcription
David A. Wacker, Donald D. Ruhl, Ehsan H. Balagamwala, Kristine M. Hope, Tong Zhang & W. Lee Kraus
Pages: 7475-7485
Published online: 27 Mar 2023
AbstractforThe DNA Binding and Catalytic Domains of Poly(ADP-Ribose) Polymerase 1 Cooperate in the Regulation of Chromatin Structure and Transcription | Full Text | References | PDF (695.5 KB)
  • 28 Views
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Article
A Regulatory Circuit Mediating Convergence between Nurr1 Transcriptional Regulation and Wnt Signaling
Hirochika Kitagawa, William J. Ray, Helmut Glantschnig, Pascale V. Nantermet, Yuanjiang Yu, Chih-Tai Leu, Shun-ichi Harada, Shigeaki Kato & Leonard P. Freedman
Pages: 7486-7496
Published online: 27 Mar 2023
AbstractforA Regulatory Circuit Mediating Convergence between Nurr1 Transcriptional Regulation and Wnt Signaling | Full Text | References | PDF (891.5 KB)
  • 46 Views
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Article
Conditional Deletion of Activating Protein 2α (AP-2α) in the Developing Retina Demonstrates Non-Cell-Autonomous Roles for AP-2α in Optic Cup Development
Erin A. Bassett, Giuseppe F. Pontoriero, Weiguo Feng, Till Marquardt, M. Elizabeth Fini, Trevor Williams & Judith A. West-Mays
Pages: 7497-7510
Published online: 27 Mar 2023
AbstractforConditional Deletion of Activating Protein 2α (AP-2α) in the Developing Retina Demonstrates Non-Cell-Autonomous Roles for AP-2α in Optic Cup Development | Full Text | References | PDF (1.8 MB)
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Article
Different Electrostatic Potentials Define ETGE and DLG Motifs as Hinge and Latch in Oxidative Stress Response
Kit I. Tong, Balasundaram Padmanabhan, Akira Kobayashi, Chengwei Shang, Yosuke Hirotsu, Shigeyuki Yokoyama & Masayuki Yamamoto
Pages: 7511-7521
Published online: 27 Mar 2023
AbstractforDifferent Electrostatic Potentials Define ETGE and DLG Motifs as Hinge and Latch in Oxidative Stress Response | Full Text | References | PDF (822.5 KB)
  • 135 Views
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Article
Cardiac-Myocyte-Specific Excision of the Vinculin Gene Disrupts Cellular Junctions, Causing Sudden Death or Dilated Cardiomyopathy
Alice E. Zemljic-Harpf, Joel C. Miller, Scott A. Henderson, Adam T. Wright, Ana Maria Manso, Laila Elsherif, Nancy D. Dalton, Andrea K. Thor, Guy A. Perkins, Andrew D. McCulloch & Robert S. Ross
Pages: 7522-7537
Published online: 27 Mar 2023
AbstractforCardiac-Myocyte-Specific Excision of the Vinculin Gene Disrupts Cellular Junctions, Causing Sudden Death or Dilated Cardiomyopathy | Full Text | References | PDF (1.5 MB)
  • 105 Views
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Article
Activation of the RalGEF/Ral Pathway Promotes Prostate Cancer Metastasis to Bone
JuanJuan Yin, Claire Pollock, Kirsten Tracy, Monika Chock, Philip Martin, Michael Oberst & Kathleen Kelly
Pages: 7538-7550
Published online: 27 Mar 2023
AbstractforActivation of the RalGEF/Ral Pathway Promotes Prostate Cancer Metastasis to Bone | Full Text | References | PDF (580.3 KB) | Supplemental
  • 35 Views
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Article
Wnt/β-Catenin Is Essential for Intestinal Homeostasis and Maintenance of Intestinal Stem Cells
Tea Fevr, Sylvie Robine, Daniel Louvard & Joerg Huelsken
Pages: 7551-7559
Published online: 27 Mar 2023
AbstractforWnt/β-Catenin Is Essential for Intestinal Homeostasis and Maintenance of Intestinal Stem Cells | Full Text | References | PDF (860.1 KB) | Supplemental
  • 324 Views
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Article
PITX2 and β-Catenin Interactions Regulate Lef-1 Isoform Expression
Melanie Amen, Xiaoming Liu, Usha Vadlamudi, Gabriela Elizondo, Evan Diamond, John F. Engelhardt & Brad A. Amendt
Pages: 7560-7573
Published online: 27 Mar 2023
AbstractforPITX2 and β-Catenin Interactions Regulate Lef-1 Isoform Expression | Full Text | References | PDF (814.7 KB)
  • 41 Views
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Article
DLGH1 Is a Negative Regulator of T-Lymphocyte Proliferation
Linda M. Stephenson, Bénédicte Sammut, Daniel B. Graham, Joaquim Chan-Wang, Karry L. Brim, Alan S. Huett, Ana V. Miletic, Tracie Kloeppel, Aimee Landry, Ramnik Xavier & Wojciech Swat
Pages: 7574-7581
Published online: 27 Mar 2023
AbstractforDLGH1 Is a Negative Regulator of T-Lymphocyte Proliferation | Full Text | References | PDF (549 KB) | Supplemental
  • 9 Views
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Article
G Protein-Coupled Receptor Ca2+-Linked Mitochondrial Reactive Oxygen Species Are Essential for Endothelial/Leukocyte Adherence
Brian J. Hawkins, Laura A. Solt, Ibrul Chowdhury, Altaf S. Kazi, M. Ruhul Abid, William C. Aird, Michael J. May, J. Kevin Foskett & Muniswamy Madesh
Pages: 7582-7593
Published online: 27 Mar 2023
AbstractforG Protein-Coupled Receptor Ca2+-Linked Mitochondrial Reactive Oxygen Species Are Essential for Endothelial/Leukocyte Adherence | Full Text | References | PDF (1.7 MB) | Supplemental
  • 25 Views
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Article
Structural Changes in Mcm5 Protein Bypass Cdc7-Dbf4 Function and Reduce Replication Origin Efficiency in Saccharomyces cerevisiae
Margaret L. Hoang, Ronald P. Leon, Luis Pessoa-Brandao, Sonia Hunt, M. K. Raghuraman, Walton L. Fangman, Bonita J. Brewer & Robert A. Sclafani
Pages: 7594-7602
Published online: 27 Mar 2023
AbstractforStructural Changes in Mcm5 Protein Bypass Cdc7-Dbf4 Function and Reduce Replication Origin Efficiency in Saccharomyces cerevisiae | Full Text | References | PDF (430.6 KB)
  • 31 Views
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Article
Activation of p53 Function by Human Transcriptional Coactivator PC4: Role of Protein-Protein Interaction, DNA Bending, and Posttranslational Modifications
Kiran Batta & Tapas K. Kundu
Pages: 7603-7614
Published online: 27 Mar 2023
AbstractforActivation of p53 Function by Human Transcriptional Coactivator PC4: Role of Protein-Protein Interaction, DNA Bending, and Posttranslational Modifications | Full Text | References | PDF (694.9 KB)
  • 36 Views
  • 42 CrossRef citations
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Article
Skp2B Stimulates Mammary Gland Development by Inhibiting REA, the Repressor of the Estrogen Receptor
Karina Umanskaya, Susanne Radke, Harish Chander, Rosie Monardo, Xinsong Xu, Zhen-Qiang Pan, Matthew J. O'Connell & Doris Germain
Pages: 7615-7622
Published online: 27 Mar 2023
AbstractforSkp2B Stimulates Mammary Gland Development by Inhibiting REA, the Repressor of the Estrogen Receptor | Full Text | References | PDF (737.8 KB)
  • 10 Views
  • 14 CrossRef citations
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Article
Nemo-Like Kinase-Myocyte Enhancer Factor 2A Signaling Regulates Anterior Formation in Xenopus Development
Kiyotoshi Satoh, Junji Ohnishi, Atsushi Sato, Michio Takeyama, Shun-ichiro Iemura, Tohru Natsume & Hiroshi Shibuya
Pages: 7623-7630
Published online: 27 Mar 2023
AbstractforNemo-Like Kinase-Myocyte Enhancer Factor 2A Signaling Regulates Anterior Formation in Xenopus Development | Full Text | References | PDF (584.4 KB)
  • 14 Views
  • 20 CrossRef citations
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Article
The Tom1L1-Clathrin Heavy Chain Complex Regulates Membrane Partitioning of the Tyrosine Kinase Src Required for Mitogenic and Transforming Activities
Guillaume Collin, Mélanie Franco, Valérie Simon, Christine Bénistant & Serge Roche
Pages: 7631-7640
Published online: 27 Mar 2023
AbstractforThe Tom1L1-Clathrin Heavy Chain Complex Regulates Membrane Partitioning of the Tyrosine Kinase Src Required for Mitogenic and Transforming Activities | Full Text | References | PDF (961.2 KB)
  • 14 Views
  • 16 CrossRef citations
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Article
Regulation of Gene Transcription by the Histone H2A N-Terminal Domain
Michael A. Parra & John J. Wyrick
Pages: 7641-7648
Published online: 27 Mar 2023
AbstractforRegulation of Gene Transcription by the Histone H2A N-Terminal Domain | Full Text | References | PDF (3.4 MB) | Supplemental
  • 9 Views
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Article
CUB Domain-Containing Protein 1 Is a Novel Regulator of Anoikis Resistance in Lung Adenocarcinoma
Takamasa Uekita, Lin Jia, Mako Narisawa-Saito, Jun Yokota, Tohru Kiyono & Ryuichi Sakai
Pages: 7649-7660
Published online: 27 Mar 2023
AbstractforCUB Domain-Containing Protein 1 Is a Novel Regulator of Anoikis Resistance in Lung Adenocarcinoma | Full Text | References | PDF (615.1 KB) | Supplemental
  • 23 Views
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Article
A Hox-Eya-Pax Complex Regulates Early Kidney Developmental Gene Expression
Ke-Qin Gong, Alisha R. Yallowitz, Hanshi Sun, Gregory R. Dressler & Deneen M. Wellik
Pages: 7661-7668
Published online: 27 Mar 2023
AbstractforA Hox-Eya-Pax Complex Regulates Early Kidney Developmental Gene Expression | Full Text | References | PDF (569.4 KB) | Supplemental
  • 22 Views
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Article
Mutation at the Polymerase Active Site of Mouse DNA Polymerase δ Increases Genomic Instability and Accelerates Tumorigenesis
Ranga N. Venkatesan, Piper M. Treuting, Evan D. Fuller, Robert E. Goldsby, Thomas H. Norwood, Ted A. Gooley, Warren C. Ladiges, Bradley D. Preston & Lawrence A. Loeb
Pages: 7669-7682
Published online: 27 Mar 2023
AbstractforMutation at the Polymerase Active Site of Mouse DNA Polymerase δ Increases Genomic Instability and Accelerates Tumorigenesis | Full Text | References | PDF (1.2 MB)
  • 34 Views
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Article
Essential Role of Endothelial Smad4 in Vascular Remodeling and Integrity
Yu Lan, Bing Liu, Huiyu Yao, Fangfei Li, Tujun Weng, Guan Yang, Wenlong Li, Xuan Cheng, Ning Mao & Xiao Yang
Pages: 7683-7692
Published online: 27 Mar 2023
AbstractforEssential Role of Endothelial Smad4 in Vascular Remodeling and Integrity | Full Text | References | PDF (1.3 MB)
  • 59 Views
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Article
Maf1 Is Involved in Coupling Carbon Metabolism to RNA Polymerase III Transcription
Małgorzata Cieśla, Joanna Towpik, Damian Graczyk, Danuta Oficjalska-Pham, Olivier Harismendy, Audrey Suleau, Karol Balicki, Christine Conesa, Olivier Lefebvre & Magdalena Boguta
Pages: 7693-7702
Published online: 27 Mar 2023
AbstractforMaf1 Is Involved in Coupling Carbon Metabolism to RNA Polymerase III Transcription | Full Text | References | PDF (370 KB) | Supplemental
  • 69 Views
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Article
E-Cadherin Is Required for Caveolin-1-Mediated Down-Regulation of the Inhibitor of Apoptosis Protein Survivin via Reduced β-Catenin-Tcf/Lef-Dependent Transcription
Vicente A. Torres, Julio C. Tapia, Diego A. Rodriguez, Alvaro Lladser, Cristian Arredondo, Lisette Leyton & Andrew F. G. Quest
Pages: 7703-7717
Published online: 27 Mar 2023
AbstractforE-Cadherin Is Required for Caveolin-1-Mediated Down-Regulation of the Inhibitor of Apoptosis Protein Survivin via Reduced β-Catenin-Tcf/Lef-Dependent Transcription | Full Text | References | PDF (878.4 KB) | Supplemental
  • 40 Views
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Article
EWI-2/CD316 Is an Inducible Receptor of HSPA8 on Human Dendritic Cells
Sandra Kettner, Frank Kalthoff, Philipp Graf, Elisabeth Priller, Franz Kricek, Ivan Lindley & Tamás Schweighoffer
Pages: 7718-7726
Published online: 27 Mar 2023
AbstractforEWI-2/CD316 Is an Inducible Receptor of HSPA8 on Human Dendritic Cells | Full Text | References | PDF (349.5 KB)
  • 12 Views
  • 20 CrossRef citations
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Article
Improved Glucose Homeostasis in Mice with Muscle-Specific Deletion of Protein-Tyrosine Phosphatase 1B
Mirela Delibegovic, Kendra K. Bence, Nimesh Mody, Eun-Gyoung Hong, Hwi Jin Ko, Jason K. Kim, Barbara B. Kahn & Benjamin G. Neel
Pages: 7727-7734
Published online: 27 Mar 2023
AbstractforImproved Glucose Homeostasis in Mice with Muscle-Specific Deletion of Protein-Tyrosine Phosphatase 1B | Full Text | References | PDF (331.5 KB)
  • 28 Views
  • 132 CrossRef citations
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Article
Restricting Conformational Flexibility of the Switch II Region Creates a Dominant-Inhibitory Phenotype in Obg GTPase Nog1
Yevgeniya R. Lapik, Julia M. Misra, Lester F. Lau & Dimitri G. Pestov
Pages: 7735-7744
Published online: 27 Mar 2023
AbstractforRestricting Conformational Flexibility of the Switch II Region Creates a Dominant-Inhibitory Phenotype in Obg GTPase Nog1 | Full Text | References | PDF (763.7 KB)
  • 17 Views
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Article
Break-Induced Loss of Heterozygosity in Fission Yeast: Dual Roles for Homologous Recombination in Promoting Translocations and Preventing De Novo Telomere Addition
Jason K. Cullen, Sharon P. Hussey, Carol Walker, John Prudden, Boon-Yu Wee, Anoushka Davé, James S. Findlay, Andrew P. Savory & Timothy C. Humphrey
Pages: 7745-7757
Published online: 27 Mar 2023
AbstractforBreak-Induced Loss of Heterozygosity in Fission Yeast: Dual Roles for Homologous Recombination in Promoting Translocations and Preventing De Novo Telomere Addition | Full Text | References | PDF (341.9 KB) | Supplemental
  • 23 Views
  • 26 CrossRef citations
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Article
Requirement of RAD52 Group Genes for Postreplication Repair of UV-Damaged DNA in Saccharomyces cerevisiae
Venkateswarlu Gangavarapu, Satya Prakash & Louise Prakash
Pages: 7758-7764
Published online: 27 Mar 2023
AbstractforRequirement of RAD52 Group Genes for Postreplication Repair of UV-Damaged DNA in Saccharomyces cerevisiae | Full Text | References | PDF (376 KB)
  • 17 Views
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