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Original Article

Evidence of the involvement of caspase-1 under physiologic and pathologic cellular stress during human pregnancy: A link between the inflammasome and parturition

, , MD, , , , , , , , , , , , , , , , & show all
Pages 605-616 | Received 01 Jan 2008, Accepted 21 Mar 2008, Published online: 07 Jul 2009

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Read on this site (20)

Sun Min Kim, Roberto Romero, JoonHo Lee, Piya Chaemsaithong, Min-Woo Lee, Noppadol Chaiyasit, Hyo-Jin Lee & Bo Hyun Yoon. (2023) About one-half of early spontaneous preterm deliveries can be identified by a rapid matrix metalloproteinase-8 (MMP-8) bedside test at the time of mid-trimester genetic amniocentesis*. The Journal of Maternal-Fetal & Neonatal Medicine 29:15, pages 2414-2422.
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Lami Yeo, Roberto Romero, Tinnakorn Chaiworapongsa, Robert Para, Jeffrey Johnson, David Kmak, Eunjung Jung, Bo Hyun Yoon & Chaur-Dong Hsu. (2022) Resolution of acute cervical insufficiency after antibiotics in a case with amniotic fluid sludge. The Journal of Maternal-Fetal & Neonatal Medicine 35:25, pages 5416-5426.
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Hassendrini N. Peiris, Roberto Romero, Kanchan Vaswani, Sarah Reed, Nardhy Gomez-Lopez, Adi L. Tarca, Dereje W. Gudicha, Offer Erez, Eli Maymon & Murray D. Mitchell. (2021) Preterm labor is characterized by a high abundance of amniotic fluid prostaglandins in patients with intra-amniotic infection or sterile intra-amniotic inflammation. The Journal of Maternal-Fetal & Neonatal Medicine 34:24, pages 4009-4024.
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Nardhy Gomez-Lopez, Roberto Romero, Bogdan Panaitescu, Derek Miller, Chengrui Zou, Dereje W. Gudicha, Adi L. Tarca, Robert Para, Percy Pacora, Sonia S. Hassan & Chaur-Dong Hsu. (2021) Gasdermin D: in vivo evidence of pyroptosis in spontaneous labor at term. The Journal of Maternal-Fetal & Neonatal Medicine 34:4, pages 569-579.
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Bogdan Panaitescu, Roberto Romero, Nardhy Gomez-Lopez, Yi Xu, Yaozhu Leng, Eli Maymon, Percy Pacora, Offer Erez, Lami Yeo, Sonia S. Hassan & Chaur-Dong Hsu. (2019) In vivo evidence of inflammasome activation during spontaneous labor at term. The Journal of Maternal-Fetal & Neonatal Medicine 32:12, pages 1978-1991.
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Kyung Joon Oh, Joon-Seok Hong, Roberto Romero & Bo Hyun Yoon. (2019) The frequency and clinical significance of intra-amniotic inflammation in twin pregnancies with preterm labor and intact membranes. The Journal of Maternal-Fetal & Neonatal Medicine 32:4, pages 527-541.
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Piya Chaemsaithong, Roberto Romero, Steven J. Korzeniewski, Alicia Martinez-Varea, Zhong Dong, Bo Hyun Yoon, Sonia S. Hassan, Tinnakorn Chaiworapongsa & Lami Yeo. (2016) A rapid interleukin-6 bedside test for the identification of intra-amniotic inflammation in preterm labor with intact membranes. The Journal of Maternal-Fetal & Neonatal Medicine 29:3, pages 349-359.
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Sun Min Kim, Roberto Romero, Jeong Woo Park, Kyung Joon Oh, Jong Kwan Jun & Bo Hyun Yoon. (2015) The relationship between the intensity of intra-amniotic inflammation and the presence and severity of acute histologic chorioamnionitis in preterm gestation. The Journal of Maternal-Fetal & Neonatal Medicine 28:13, pages 1500-1509.
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Yeon Mee Kim, Piya Chaemsaithong, Roberto Romero, Majid Shaman, Chong Jai Kim, Jung-Sun Kim, Faisal Qureshi, Suzanne M. Jacques, Ahmed I. Ahmed, Tinnakorn Chaiworapongsa, Sonia S. Hassan, Lami Yeo & Steven J. Korzeniewski. (2015) Placental lesions associated with acute atherosis. The Journal of Maternal-Fetal & Neonatal Medicine 28:13, pages 1554-1562.
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Roberto Romero, Jezid Miranda, Piya Chaemsaithong, Tinnakorn Chaiworapongsa, Juan P. Kusanovic, Zhong Dong, Ahmed I. Ahmed, Majid Shaman, Kia Lannaman, Bo Hyun Yoon, Sonia S. Hassan, Chong Jai Kim, Steven Jai Korzeniewski, Lami Yeo & Yeon Mee Kim. (2015) Sterile and microbial-associated intra-amniotic inflammation in preterm prelabor rupture of membranes. The Journal of Maternal-Fetal & Neonatal Medicine 28:12, pages 1394-1409.
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Roberto Romero, Jezid Miranda, Tinnakorn Chaiworapongsa, Piya Chaemsaithong, Francesca Gotsch, Zhong Dong, Ahmed I. Ahmed, Bo Hyun Yoon, Sonia S. Hassan, Chong J. Kim, Steven J. Korzeniewski, Lami Yeo & Yeon Mee Kim. (2015) Sterile intra-amniotic inflammation in asymptomatic patients with a sonographic short cervix: prevalence and clinical significance. The Journal of Maternal-Fetal & Neonatal Medicine 28:11, pages 1343-1359.
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Vanessa Topping, Roberto Romero, Nandor Gabor Than, Adi L. Tarca, Zhonghui Xu, Sun Young Kim, Bing Wang, Lami Yeo, Chong Jai Kim, Sonia S. Hassan & Jung-Sun Kim. (2013) Interleukin-33 in the human placenta. The Journal of Maternal-Fetal & Neonatal Medicine 26:4, pages 327-338.
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Seung Mi Lee, Roberto Romero, Jeong Woo Park, Sun Min Kim, Chan-Wook Park, Steven J. Korzeniewski, Tinnakorn Chaiworapongsa & Bo Hyun Yoon. (2012) The clinical significance of a positive Amnisure test in women with preterm labor and intact membranes. The Journal of Maternal-Fetal & Neonatal Medicine 25:9, pages 1690-1698.
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Roberto Romero, Eleazar Soto, Stanley M. Berry, Sonia S. Hassan, Juan Pedro Kusanovic, Bo Hyun Yoon, Samuel Edwin, Moshe Mazor & Tinnakorn Chaiworapongsa. (2012) Blood pH and gases in fetuses in preterm labor with and without systemic inflammatory response syndrome. The Journal of Maternal-Fetal & Neonatal Medicine 25:7, pages 1160-1170.
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Seung Mi Lee, Roberto Romero, Kyung A. Lee, Hye Jin Yang, Kyung Joon Oh, Chan-Wook Park & Bo Hyun Yoon. (2011) The frequency and risk factors of funisitis and histologic chorioamnionitis in pregnant women at term who delivered after the spontaneous onset of labor. The Journal of Maternal-Fetal & Neonatal Medicine 24:1, pages 37-42.
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Roberto Romero, Shali Mazaki-Tovi, Edi Vaisbuch, Juan Pedro Kusanovic, Tinnakorn Chaiworapongsa, Ricardo Gomez, Jyh Kae Nien, Bo Hyun Yoon, Moshe Mazor, Jingqin Luo, David Banks, John Ryals & Chris Beecher. (2010) Metabolomics in premature labor: a novel approach to identify patients at risk for preterm delivery. The Journal of Maternal-Fetal & Neonatal Medicine 23:12, pages 1344-1359.
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Roberto Romero, Juan Pedro Kusanovic, Hernan Muñoz, Ricardo Gomez, Ronald F. Lamont & Lami Yeo. (2010) Allergy-induced preterm labor after the ingestion of shellfish. The Journal of Maternal-Fetal & Neonatal Medicine 23:4, pages 351-359.
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Roberto Romero, Juan Pedro Kusanovic, Ricardo Gomez, Ronald Lamont, Egle Bytautiene, Robert E. Garfield, Pooja Mittal, Sonia S. Hassan & Lami Yeo. (2010) The clinical significance of eosinophils in the amniotic fluid in preterm labor. The Journal of Maternal-Fetal & Neonatal Medicine 23:4, pages 320-329.
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Pooja Mittal, Roberto Romero, Shali Mazaki-Tovi, Gerard Tromp, Adi L. Tarca, Yeon M. Kim, Tinnakorn Chaiworapongsa, Juan Pedro Kusanovic, Offer Erez, Nandor Gabor Than & Sonia S. Hassan. (2009) Fetal membranes as an interface between inflammation and metabolism: Increased Aquaporin 9 expression in the presence of spontaneous labor at term and chorioamnionitis. The Journal of Maternal-Fetal & Neonatal Medicine 22:12, pages 1167-1175.
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Francesca Gotsch, Francesca Gotsch, Roberto Romero, Offer Erez, Edi Vaisbuch, Juan Pedro Kusanovic, Shali Mazaki-Tovi, Sun Kwon Kim, Sonia Hassan & Lami Yeo. (2009) The preterm parturition syndrome and its implications for understanding the biology, risk assessment, diagnosis, treatment and prevention of preterm birth. The Journal of Maternal-Fetal & Neonatal Medicine 22:sup2, pages 5-23.
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Gaurav Bhatti, Roberto Romero, Nardhy Gomez-Lopez, Tinnakorn Chaiworapongsa, Nandor Gabor Than, Kevin R. Theis, Jose Galaz, Francesca Gotsch, Roger Pique-Regi, Stanley M. Berry, Mahendra Kavdia & Adi L. Tarca. (2023) The amniotic fluid proteome changes with term labor and informs biomarker discovery in maternal plasma. Scientific Reports 13:1.
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Hossam El-Sheikh Ali, Pouya Dini, Kirsten Scoggin, Shavahn Loux, Carleigh Fedorka, Yatta Boakari, Jamie Norris, Alejandro Esteller-Vico, Theodore Kalbfleisch & Barry Ball. (2021) Transcriptomic analysis of equine placenta reveals key regulators and pathways involved in ascending placentitis†. Biology of Reproduction 104:3, pages 638-656.
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Nardhy Gomez-Lopez & Roberto Romero. 2021. Reproductive Immunology. Reproductive Immunology 207 237 .
K Motomura, R Romero, V Garcia-Flores, Y Leng, Y Xu, J Galaz, R Slutsky, D Levenson & N Gomez-Lopez. (2020) The alarmin interleukin-1α causes preterm birth through the NLRP3 inflammasome. Molecular Human Reproduction 26:9, pages 712-726.
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Jinming Zhu, Chunling Ma, Lina Zhu, Juan Li, Fengyun Peng, Lei Huang & Xiaomei Luan. (2020) A role for the NLRC4 inflammasome in premature rupture of membrane. PLOS ONE 15:8, pages e0237847.
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Marilyne Lavergne, Corinne Belville, Héléna Choltus, Christelle Gross, Régine Minet-Quinard, Denis Gallot, Vincent Sapin & Loïc Blanchon. (2020) Human Amnion Epithelial Cells (AECs) Respond to the FSL-1 Lipopeptide by Engaging the NLRP7 Inflammasome. Frontiers in Immunology 11.
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Chiara Tersigni, Manu Vatish, Silvia D’Ippolito, Giovanni Scambia & Nicoletta Di Simone. (2020) Abnormal uterine inflammation in obstetric syndromes: molecular insights into the role of chemokine decoy receptor D6 and inflammasome NLRP3. Molecular Human Reproduction 26:2, pages 111-121.
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Kevin R. Theis, Roberto Romero, Kenichiro Motomura, Jose Galaz, Andrew D. Winters, Percy Pacora, Derek Miller, Rebecca Slutsky, Violetta Florova, Dustyn Levenson, Robert Para, Aneesha Varrey, Marian Kacerovsky, Chaur-Dong Hsu & Nardhy Gomez-Lopez. (2020) Microbial burden and inflammasome activation in amniotic fluid of patients with preterm prelabor rupture of membranes. Journal of Perinatal Medicine 48:2, pages 115-131.
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Gaurav Bhatti, Roberto Romero, Gregory Edward Rice, Wendy Fitzgerald, Percy Pacora, Nardhy Gomez-Lopez, Mahendra Kavdia, Adi L. Tarca & Leonid Margolis. (2020) Compartmentalized profiling of amniotic fluid cytokines in women with preterm labor. PLOS ONE 15:1, pages e0227881.
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Nardhy Gomez-Lopez, Roberto Romero, George Schwenkel, Valeria Garcia-Flores, Bogdan Panaitescu, Aneesha Varrey, Fatime Ayoub, Sonia S. Hassan & Mark Phillippe. (2020) Cell-Free Fetal DNA Increases Prior to Labor at Term and in a Subset of Preterm Births. Reproductive Sciences 27:1, pages 218-232.
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Nardhy Gomez-Lopez, Kenichiro Motomura, Derek Miller, Valeria Garcia-Flores, Jose Galaz & Roberto Romero. (2019) Inflammasomes: Their Role in Normal and Complicated Pregnancies. The Journal of Immunology 203:11, pages 2757-2769.
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Silvana Pereyra, Claudio Sosa, Bernardo Bertoni & Rossana Sapiro. (2019) Transcriptomic analysis of fetal membranes reveals pathways involved in preterm birth. BMC Medical Genomics 12:1.
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Nardhy Gomez‐Lopez, Roberto Romero, Adi L. Tarca, Derek Miller, Bogdan Panaitescu, George Schwenkel, Dereje W. Gudicha, Sonia S. Hassan, Percy Pacora, Eunjung Jung & Chaur‐Dong Hsu. (2019) Gasdermin D: Evidence of pyroptosis in spontaneous preterm labor with sterile intra‐amniotic inflammation or intra‐amniotic infection. American Journal of Reproductive Immunology 82:6.
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Bo Hyun Yoon, Roberto Romero, Jee Yoon Park, Kyung Joon Oh, JoonHo Lee, Agustin Conde-Agudelo & Joon-Seok Hong. (2019) Antibiotic administration can eradicate intra-amniotic infection or intra-amniotic inflammation in a subset of patients with preterm labor and intact membranes. American Journal of Obstetrics and Gynecology 221:2, pages 142.e1-142.e22.
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Kyung Joon Oh, Roberto Romero, Jee Yoon Park, JoonHo Lee, Agustin Conde-Agudelo, Joon-Seok Hong & Bo Hyun Yoon. (2019) Evidence that antibiotic administration is effective in the treatment of a subset of patients with intra-amniotic infection/inflammation presenting with cervical insufficiency. American Journal of Obstetrics and Gynecology 221:2, pages 140.e1-140.e18.
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Nardhy Gomez-Lopez, Roberto Romero, Valeria Garcia-Flores, Yaozhu Leng, Derek Miller, Sonia S Hassan, Chaur-Dong Hsu & Bogdan Panaitescu. (2019) Inhibition of the NLRP3 inflammasome can prevent sterile intra-amniotic inflammation, preterm labor/birth, and adverse neonatal outcomes†. Biology of Reproduction 100:5, pages 1306-1318.
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Jonathan Faro, Roberto Romero, George Schwenkel, Valeria Garcia-Flores, Marcia Arenas-Hernandez, Yaozhu Leng, Yi Xu, Derek Miller, Sonia S Hassan & Nardhy Gomez-Lopez. (2019) Intra-amniotic inflammation induces preterm birth by activating the NLRP3 inflammasome†. Biology of Reproduction 100:5, pages 1290-1305.
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Kelly Q. Zhou, Colin R. Green, Laura Bennet, Alistair J. Gunn & Joanne O. Davidson. (2019) The Role of Connexin and Pannexin Channels in Perinatal Brain Injury and Inflammation. Frontiers in Physiology 10.
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Nardhy Gomez‐Lopez, Roberto Romero, Bogdan Panaitescu, Yaozhu Leng, Yi Xu, Adi L. Tarca, Jonathan Faro, Percy Pacora, Sonia S. Hassan & Chaur‐Dong Hsu. (2018) Inflammasome activation during spontaneous preterm labor with intra‐amniotic infection or sterile intra‐amniotic inflammation. American Journal of Reproductive Immunology 80:5.
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Cheng-Yi Chen, Chia-Yu Chen, Chang-Ching Liu & Chie-Pein Chen. (2018) Omega-3 polyunsaturated fatty acids reduce preterm labor by inhibiting trophoblast cathepsin S and inflammasome activation. Clinical Science 132:20, pages 2221-2239.
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Roberto Romero, Yeon Mee Kim, Percy Pacora, Chong Jai Kim, Neta Benshalom-Tirosh, Sunil Jaiman, Gaurav Bhatti, Jung-Sun Kim, Faisal Qureshi, Suzanne M. Jacques, Eun Jung Jung, Lami Yeo, Bogdan Panaitescu, Eli Maymon, Sonia S. Hassan, Chaur-Dong Hsu & Offer Erez. (2018) The frequency and type of placental histologic lesions in term pregnancies with normal outcome. Journal of Perinatal Medicine 46:6, pages 613-630.
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Roberto Romero, Yi Xu, Olesya Plazyo, Piya Chaemsaithong, Tinnakorn Chaiworapongsa, Ronald Unkel, Nandor Gabor Than, Po Jen Chiang, Zhong Dong, Zhonghui Xu, Adi L. Tarca, Vikki M. Abrahams, Sonia S. Hassan, Lami Yeo & Nardhy Gomez‐Lopez. (2016) A Role for the Inflammasome in Spontaneous Labor at Term. American Journal of Reproductive Immunology 79:6.
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Thomas A. Hooven, Tara M. Randis & Richard A. Polin. (2018) What’s the harm? Risks and benefits of evolving rule-out sepsis practices. Journal of Perinatology 38:6, pages 614-622.
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Jerome F. StraussIIIIII, Roberto Romero, Nardhy Gomez-Lopez, Hannah Haymond-Thornburg, Bhavi P. Modi, Maria E. Teves, Laurel N. Pearson, Timothy P. York & Harvey A. Schenkein. (2018) Spontaneous preterm birth: advances toward the discovery of genetic predisposition. American Journal of Obstetrics and Gynecology 218:3, pages 294-314.e2.
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Kyung Joon Oh, Jee Yoon Park, JoonHo Lee, Joon-Seok Hong, Roberto Romero & Bo Hyun Yoon. (2018) The combined exposure to intra-amniotic inflammation and neonatal respiratory distress syndrome increases the risk of intraventricular hemorrhage in preterm neonates. Journal of Perinatal Medicine 46:1, pages 9-20.
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Bhavi P. Modi, Maria E. Teves, Laurel N. Pearson, Hardik I. Parikh, Hannah Haymond-Thornburg, John L. Tucker, Piya Chaemsaithong, Nardhy Gomez-Lopez, Timothy P. York, Roberto Romero & Jerome F. StraussIIIIII. (2017) Mutations in fetal genes involved in innate immunity and host defense against microbes increase risk of preterm premature rupture of membranes (PPROM). Molecular Genetics & Genomic Medicine 5:6, pages 720-729.
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Sarah N. Cross, Julie A. Potter, Paulomi Aldo, Ja Young Kwon, Mary Pitruzzello, Mancy Tong, Seth Guller, Carla V. Rothlin, Gil Mor & Vikki M. Abrahams. (2017) Viral Infection Sensitizes Human Fetal Membranes to Bacterial Lipopolysaccharide by MERTK Inhibition and Inflammasome Activation. The Journal of Immunology 199:8, pages 2885-2895.
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Nardhy Gomez-Lopez, Roberto Romero, Yi Xu, Olesya Plazyo, Ronald Unkel, Yaozhu Leng, Nandor Gabor Than, Tinnakorn Chaiworapongsa, Bogdan Panaitescu, Zhong Dong, Adi L. Tarca, Vikki M. Abrahams, Lami Yeo & Sonia S. Hassan. (2017) A Role for the Inflammasome in Spontaneous Preterm Labor With Acute Histologic Chorioamnionitis. Reproductive Sciences 24:10, pages 1382-1401.
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Kazuhiro Tamura, Gen Ishikawa, Mikihiro Yoshie, Wakana Ohneda, Akihito Nakai, Toshiyuki Takeshita & Eiichi Tachikawa. (2017) Glibenclamide inhibits NLRP3 inflammasome-mediated IL-1β secretion in human trophoblasts. Journal of Pharmacological Sciences 135:2, pages 89-95.
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Roberto Romero, Piya Chaemsaithong, Noppadol Chaiyasit, Nikolina Docheva, Zhong Dong, Chong Jai Kim, Yeon Mee Kim, Jung-Sun Kim, Faisal Qureshi, Suzanne M. Jacques, Bo Hyun Yoon, Tinnakorn Chaiworapongsa, Lami Yeo, Sonia S. Hassan, Offer Erez & Steven J. Korzeniewski. (2017) CXCL10 and IL-6: Markers of two different forms of intra-amniotic inflammation in preterm labor. American Journal of Reproductive Immunology 78:1, pages e12685.
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Nardhy Gomez-Lopez, Roberto Romero, Yi Xu, Olesya Plazyo, Ronald Unkel, Nandor Gabor Than, Piya Chaemsaithong, Tinnakorn Chaiworapongsa, Zhong Dong, Adi L. Tarca, Vikki M. Abrahams, Lami Yeo & Sonia S. Hassan. (2017) A Role for the Inflammasome in Spontaneous Labor at Term with Acute Histologic Chorioamnionitis. Reproductive Sciences 24:6, pages 934-953.
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Kyung Joon Oh, Sun Min Kim, Joon-Seok Hong, Eli Maymon, Offer Erez, Bogdan Panaitescu, Nardhy Gomez-Lopez, Roberto Romero & Bo Hyun Yoon. (2017) Twenty-four percent of patients with clinical chorioamnionitis in preterm gestations have no evidence of either culture-proven intraamniotic infection or intraamniotic inflammation. American Journal of Obstetrics and Gynecology 216:6, pages 604.e1-604.e11.
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Nardhy Gomez-Lopez, Roberto Romero, Yi Xu, Valeria Garcia-Flores, Yaozhu Leng, Bogdan Panaitescu, Derek Miller, Vikki M. Abrahams & Sonia S. Hassan. (2017) Inflammasome assembly in the chorioamniotic membranes during spontaneous labor at term. American Journal of Reproductive Immunology 77:5, pages e12648.
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Amy Winship & Evdokia Dimitriadis. (2017) Interleukin-11 induces preterm birth and modulates decidual inflammasome gene expression in mice. Placenta 50, pages 99-101.
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John V. Ilekis, Ekaterini Tsilou, Susan Fisher, Vikki M. Abrahams, Michael J. Soares, James C. Cross, Stacy Zamudio, Nicholas P. Illsley, Leslie Myatt, Christine Colvis, Maged M. Costantine, David M. Haas, Yoel Sadovsky, Carl Weiner, Erik Rytting & Gene Bidwell. (2016) Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National Institute of Child Health and Human Development. American Journal of Obstetrics and Gynecology 215:1, pages S1-S46.
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JoonHo Lee, Roberto Romero, Kyung A Lee, Eun Na Kim, Steven J. Korzeniewski, Piya Chaemsaithong & Bo Hyun Yoon. (2016) Meconium aspiration syndrome: a role for fetal systemic inflammation. American Journal of Obstetrics and Gynecology 214:3, pages 366.e1-366.e9.
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Roberto Romero, Jean-Charles Grivel, Adi L. Tarca, Piya Chaemsaithong, Zhonghui Xu, Wendy Fitzgerald, Sonia S. Hassan, Tinnakorn Chaiworapongsa & Leonid Margolis. (2015) Evidence of perturbations of the cytokine network in preterm labor. American Journal of Obstetrics and Gynecology 213:6, pages 836.e1-836.e18.
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R. N. Khan & D. P. Hay. (2014) A clear and present danger: inflammasomes DAMPing down disorders of pregnancy. Human Reproduction Update 21:3, pages 388-405.
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Irving L. M. H. Aye, Susanne Lager & Theresa L. Powell. 2015. Metabolic Syndrome and Complications of Pregnancy. Metabolic Syndrome and Complications of Pregnancy 77 90 .
S. Lager, I.L.M.H. Aye, F. Gaccioli, V.I. Ramirez, T. Jansson & T.L. Powell. (2014) Labor inhibits placental mechanistic target of rapamycin complex 1 signaling. Placenta 35:12, pages 1007-1012.
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Eric J. Vick, Hyo S. Park, Krista A. Huff, Kenneth M. Brooks, Anthony L. Farone & Mary B. Farone. (2014) Gardnerella vaginalis triggers NLRP3 inflammasome recruitment in THP-1 monocytes. Journal of Reproductive Immunology 106, pages 67-75.
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Roberto Romero, Jezid Miranda, Tinnakorn Chaiworapongsa, Steven J. Korzeniewski, Piya Chaemsaithong, Francesca Gotsch, Zhong Dong, Ahmed I. Ahmed, Bo Hyun Yoon, Sonia S. Hassan, Chong Jai Kim & Lami Yeo. (2014) Prevalence and Clinical Significance of Sterile Intra-amniotic Inflammation in Patients with Preterm Labor and Intact Membranes. American Journal of Reproductive Immunology 72:5, pages 458-474.
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Mai Hoang, Julie A. Potter, Stefan M. Gysler, Christina S. Han, Seth Guller, Errol R. Norwitz & Vikki M. Abrahams. (2014) Human Fetal Membranes Generate Distinct Cytokine Profiles in Response to Bacterial Toll-Like Receptor and Nod-Like Receptor Agonists1. Biology of Reproduction 90:2.
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Jossimara Polettini, Eliane Passarelli Vieira, Mariana Perlati dos Santos, José Carlos Peraçoli, Steven S. Witkin & Márcia Guimarães da Silva. (2012) Interleukin 18 messenger RNA and proIL-18 protein expression in chorioamniotic membranes from pregnant women with preterm prelabor rupture of membranes. European Journal of Obstetrics & Gynecology and Reproductive Biology 161:2, pages 134-139.
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Roberto Romero, Zeynep Alpay Savasan, Tinnakorn Chaiworapongsa, Stanley M. Berry, Juan Pedro Kusanovic, Sonia S. Hassan, Bo Hyun Yoon, Samuel Edwin & Moshe Mazor. (2012) Hematologic profile of the fetus with systemic inflammatory response syndrome. Journal of Perinatal Medicine 40:1.
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