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Short Communications

(3,4-Dihydroxyphenyl)(2,3,4-trihydroxyphenyl)methanone and its derivatives as carbonic anhydrase isoenzymes inhibitors

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Pages 402-406 | Received 12 Dec 2011, Accepted 21 Feb 2012, Published online: 02 Apr 2012

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Umit M. Kocyigit, Yakup Budak, Meliha Burcu Gürdere, Neşe Dürü, Parham Taslimi, İlhami Gülçin & Mustafa Ceylan. (2019) Synthesis and investigation of anticancer, antibacterial activities and carbonic anhydrase, acetylcholinesterase inhibition profiles of novel (3aR,4S,7R,7aS)-2-[4-[1-acetyl-5-(aryl/heteroaryl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl]-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-diones. Monatshefte für Chemie - Chemical Monthly 150:4, pages 721-731.
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Emre Güzel, Ümit M. Koçyiğit, Barış S. Arslan, Mehmet Ataş, Parham Taslimi, Faik Gökalp, Mehmet Nebioğlu, İlkay Şişman & İlhami Gulçin. (2019) Aminopyrazole‐substituted metallophthalocyanines: Preparation, aggregation behavior, and investigation of metabolic enzymes inhibition properties. Archiv der Pharmazie 352:2.
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Umit M. Kocyigit, Parham Taslimi & İlhami Gulçin. (2018) Characterization and inhibition effects of some metal ions on carbonic anhydrase enzyme from Kangal Akkaraman sheep. Journal of Biochemical and Molecular Toxicology 32:8, pages e22172.
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Ferhat Türker, Duygu Barut Celepci, Aydın Aktaş, Parham Taslimi, Yetkin Gök, Muhittin Aygün & İlhami Gülçin. (2018) meta -Cyanobenzyl substituted benzimidazolium salts: Synthesis, characterization, crystal structure and carbonic anhydrase, α-glycosidase, butyrylcholinesterase, and acetylcholinesterase inhibitory properties . Archiv der Pharmazie 351:7, pages 1800029.
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Parham Taslimi & İlhami Gulçin. (2018) Antioxidant and anticholinergic properties of olivetol. Journal of Food Biochemistry 42:3, pages e12516.
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Parham Taslimi, Cuneyt Caglayan, Vagif Farzaliyev, Oruj Nabiyev, Afsun Sujayev, Fikret Turkan, Ruya Kaya & İlhami Gulçin. (2018) Synthesis and discovery of potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and α-glycosidase enzymes inhibitors: The novel N , N ′-bis-cyanomethylamine and alkoxymethylamine derivatives . Journal of Biochemical and Molecular Toxicology 32:4, pages e22042.
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Fatoş Erdemir, Duygu Barut Celepci, Aydın Aktaş, Parham Taslimi, Yetkin Gök, Hasan Karabıyık & İlhami Gülçin. (2018) 2-Hydroxyethyl substituted NHC precursors: Synthesis, characterization, crystal structure and carbonic anhydrase, α-glycosidase, butyrylcholinesterase, and acetylcholinesterase inhibitory properties. Journal of Molecular Structure 1155, pages 797-806.
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Fikret Türkan, Zübeyir Huyut, Parham Taslimi & İlhami Gülçin. (2018) The in vivo effects of cefazolin, cefuroxime, and cefoperazon on the carbonic anhydrase in different rat tissues . Journal of Biochemical and Molecular Toxicology 32:3, pages e22041.
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Parham Taslimi, Afsun Sujayev, Fikret Turkan, Emin Garibov, Zübeyir Huyut, Vagif Farzaliyev, Sevgi Mamedova & İlhami Gulçin. (2018) Synthesis and investigation of the conversion reactions of pyrimidine-thiones with nucleophilic reagent and evaluation of their acetylcholinesterase, carbonic anhydrase inhibition, and antioxidant activities. Journal of Biochemical and Molecular Toxicology 32:2, pages e22019.
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Yakup Sarı, Aydın Aktaş, Parham Taslimi, Yetkin Gök & İlhami Gulçin. (2018) Novel N -propylphthalimide- and 4-vinylbenzyl-substituted benzimidazole salts: Synthesis, characterization, and determination of their metal chelating effects and inhibition profiles against acetylcholinesterase and carbonic anhydrase enzymes . Journal of Biochemical and Molecular Toxicology 32:1, pages e22009.
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Nilufer Bulut, Umit M. Kocyigit, Ibrahim H. Gecibesler, Taner Dastan, Huseyin Karci, Parham Taslimi, Sevgi Durna Dastan, Ilhami Gulcin & Ahmet Cetin. (2018) Synthesis of some novel pyridine compounds containing bis-1,2,4-triazole/thiosemicarbazide moiety and investigation of their antioxidant properties, carbonic anhydrase, and acetylcholinesterase enzymes inhibition profiles. Journal of Biochemical and Molecular Toxicology 32:1, pages e22006.
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Ümit M. Koçyiğit, Sevgi Durna Daştan, Parham Taslimi, Taner Daştan & İlhami Gülçin. (2018) Inhibitory effects of some drugs on carbonic anhydrase enzyme purified from Kangal Akkaraman sheep in Sivas, Turkey. Journal of Biochemical and Molecular Toxicology 32:1, pages e22000.
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Parham Taslimi, Cuneyt Caglayan & İlhami Gulcin. (2017) The impact of some natural phenolic compounds on carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and α-glycosidase enzymes: An antidiabetic, anticholinergic, and antiepileptic study. Journal of Biochemical and Molecular Toxicology 31:12, pages e21995.
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Umit M. Kocyigit, Yakup Budak, Fikret Eligüzel, Parham Taslimi, Deryanur Kılıç, İlhami Gulçin & Mustafa Ceylan. (2017) Synthesis and Carbonic Anhydrase Inhibition of Tetrabromo Chalcone Derivatives. Archiv der Pharmazie 350:12, pages 1700198.
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Parham Taslimi, Hülya Akıncıoglu & İlhami Gülçin. (2017) Synephrine and phenylephrine act as α‐amylase, α‐glycosidase, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase enzymes inhibitors. Journal of Biochemical and Molecular Toxicology 31:11.
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Umit M. Kocyigit, Parham Taslimi, Hayreddin Gezegen, İlhami Gulçin & Mustafa Ceylan. (2017) Evaluation of acetylcholinesterase and carbonic anhydrase inhibition profiles of 1,2,3,4,6-pentasubstituted-4-hydroxy-cyclohexanes. Journal of Biochemical and Molecular Toxicology 31:9, pages e21938.
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Parham Taslimi, Sabiya Osmanova, İlhami Gulçin, Sabira Sardarova, Vagif Farzaliyev, Afsun Sujayev, Ruya Kaya, Fatma Koc, Sukru Beydemir, Saleh H. Alwasel & Omer Irfan Kufrevioglu. (2017) Discovery of potent carbonic anhydrase, acetylcholinesterase, and butyrylcholinesterase enzymes inhibitors: The new amides and thiazolidine-4-ones synthesized on an acetophenone base. Journal of Biochemical and Molecular Toxicology 31:9, pages e21931.
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Koray Oktay, Leyla Polat Kose, Kıvılcım Şendil, Mehmet Serdar Gültekin & İlhami Gülçın. (2017) Synthesis of 3-chloro-1-substituted aryl pyrrolidine-2,5-dione derivatives: discovery of potent human carbonic anhydrase inhibitors. Medicinal Chemistry Research 26:8, pages 1619-1627.
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Parham Taslimi, Afsun Sujayev, Emin Garibov, Nazar Nazarov, Zubeyir Huyut, Saleh H. Alwasel & İlhami Gulçin. (2017) Synthesis of new cyclic thioureas and evaluation of their metal-chelating activity, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase inhibition profiles. Journal of Biochemical and Molecular Toxicology 31:7, pages e21897.
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Çetin Bayrak, Parham Taslimi, İlhami Gülçin & Abdullah Menzek. (2017) The first synthesis of 4-phenylbutenone derivative bromophenols including natural products and their inhibition profiles for carbonic anhydrase, acetylcholinesterase and butyrylcholinesterase enzymes. Bioorganic Chemistry 72, pages 359-366.
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Aydın Aktaş, Parham Taslimi, İlhami Gülçin & Yetkin Gök. (2017) Novel NHC Precursors: Synthesis, Characterization, and Carbonic Anhydrase and Acetylcholinesterase Inhibitory Properties. Archiv der Pharmazie 350:6, pages e201700045.
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Mustafa Ceylan, Umit M. Kocyigit, Necibe Canan Usta, Belma Gürbüzlü, Yusuf Temel, Saleh H. Alwasel & İlhami Gülçin. (2017) Synthesis, carbonic anhydrase I and II isoenzymes inhibition properties, and antibacterial activities of novel tetralone-based 1,4-benzothiazepine derivatives. Journal of Biochemical and Molecular Toxicology 31:4, pages e21872.
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Hulya Göcer, Akın Akıncıoğlu, Süleyman Göksu & İlhami Gülçin. (2017) Carbonic anhydrase inhibitory properties of phenolic sulfonamides derived from dopamine related compounds. Arabian Journal of Chemistry 10:3, pages 398-402.
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Fevzi Topal, Ilhami Gulcin, Arif Dastan & Murat Guney. (2017) Novel eugenol derivatives: Potent acetylcholinesterase and carbonic anhydrase inhibitors. International Journal of Biological Macromolecules 94, pages 845-851.
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Umit M. Kocyigit, Osman Nuri Aslan, Ilhami Gulcin, Yusuf Temel & Mustafa Ceylan. (2016) Synthesis and Carbonic Anhydrase Inhibition of Novel 2-(4-(Aryl)thiazole-2-yl)-3a,4,7,7a-tetrahydro-1 H -4,7-methanoisoindole-1,3(2 H )-dione Derivatives . Archiv der Pharmazie 349:12, pages 955-963.
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Ramazan Kocak, Esra Turan Akın, Pınar Kalın, Oktay Talaz, Nurullah Saracoglu, Arif Dastan, Ilhami Gülcin & Serdar Durdagi. (2016) Synthesis of Some Novel Norbornene-Fused Pyridazines as Potent Inhibitors of Carbonic Anhydrase and Acetylcholinesterase. Journal of Heterocyclic Chemistry 53:6, pages 2049-2056.
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Hayriye Genç, Ramazan Kalin, Zeynep Köksal, Nastaran Sadeghian, Umit Kocyigit, Mustafa Zengin, İlhami Gülçin & Hasan Özdemir. (2016) Discovery of Potent Carbonic Anhydrase and Acetylcholinesterase Inhibitors: 2-Aminoindan β-Lactam Derivatives. International Journal of Molecular Sciences 17:10, pages 1736.
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Bünyamin Özgeriş, Süleyman Göksu, Leyla Polat Köse, İlhami Gülçin, Ramin Ekhteiari Salmas, Serdar Durdagi, Ferhan Tümer & Claudiu T. Supuran. (2016) Acetylcholinesterase and carbonic anhydrase inhibitory properties of novel urea and sulfamide derivatives incorporating dopaminergic 2-aminotetralin scaffolds. Bioorganic & Medicinal Chemistry 24:10, pages 2318-2329.
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Tekin Artunç, Yasin Çetinkaya, Hülya Göçer, İlhami Gülçin, Abdullah Menzek, Ertan Şahin & Claudiu T. Supuran. (2016) Synthesis of 4-[2-(3,4-dimethoxybenzyl)cyclopentyl]-1,2-dimethoxybenzene Derivatives and Evaluations of Their Carbonic Anhydrase Isoenzymes Inhibitory Effects. Chemical Biology & Drug Design 87:4, pages 594-607.
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Akın Akıncıoğlu, Hülya Akıncıoğlu, İlhami Gülçin, Serdar Durdagi, Claudiu T. Supuran & Süleyman Göksu. (2015) Discovery of potent carbonic anhydrase and acetylcholine esterase inhibitors: Novel sulfamoylcarbamates and sulfamides derived from acetophenones. Bioorganic & Medicinal Chemistry 23:13, pages 3592-3602.
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Alper Yıldırım, Ufuk Atmaca, Ali Keskin, Meryem Topal, Murat Çelik, İlhami Gülçin & Claudiu T. Supuran. (2015) N-Acylsulfonamides strongly inhibit human carbonic anhydrase isoenzymes I and II. Bioorganic & Medicinal Chemistry 23:10, pages 2598-2605.
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Murat Boztaş, Yasin Çetinkaya, Meryem Topal, İlhami Gülçin, Abdullah Menzek, Ertan Şahin, Muhammet Tanc & Claudiu T. Supuran. (2014) Synthesis and Carbonic Anhydrase Isoenzymes I, II, IX, and XII Inhibitory Effects of Dimethoxybromophenol Derivatives Incorporating Cyclopropane Moieties. Journal of Medicinal Chemistry 58:2, pages 640-650.
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Betul Arabaci, Ilhami Gulcin & Saleh Alwasel. (2014) Capsaicin: A Potent Inhibitor of Carbonic Anhydrase Isoenzymes. Molecules 19:7, pages 10103-10114.
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Yasin Çetinkaya, Hülya Göçer, İlhami Gülçin & Abdullah Menzek. (2014) Synthesis and Carbonic Anhydrase Isoenzymes Inhibitory Effects of Brominated Diphenylmethanone and Its Derivatives. Archiv der Pharmazie 347:5, pages 354-359.
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