Leukemia & Lymphoma, Volume 59, Issue 11 (2018)

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Leukemia & Lymphoma, Volume 59, Issue 11 (2018)

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Commentary

Revisiting the role of radiotherapy in Hodgkin lymphoma to augment systemic immunity
Richard C. Walshaw & Timothy M. Illidge
Pages: 2519-2520
Published online: 22 Jun 2018
CitationforRevisiting the role of radiotherapy in Hodgkin lymphoma to augment systemic immunity | Full Text | References | PDF (240.7 KB) | Supplemental
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Multiple myeloma – a cure within reach
Morie A. Gertz
Pages: 2521-2523
Published online: 04 Apr 2018
First Page PreviewforMultiple myeloma – a cure within reach | Full Text | References | PDF (407.8 KB) | Supplemental
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Review

PI3K/AKT/mTOR pathway in multiple myeloma: from basic biology to clinical promise
Vijay Ramakrishnan & Shaji Kumar
Pages: 2524-2534
Published online: 11 Jan 2018
AbstractforPI3K/AKT/mTOR pathway in multiple myeloma: from basic biology to clinical promise | Full Text | References | PDF (1.2 MB) | Supplemental
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Targeting the bone marrow microenvironment in acute leukemia
Christina Karantanou, Parimala Sonika Godavarthy & Daniela S. Krause
Pages: 2535-2545
Published online: 12 Feb 2018
AbstractforTargeting the bone marrow microenvironment in acute leukemia | Full Text | References | PDF (1.1 MB) | Supplemental
  • 924 Views
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Current concepts in tumor imaging with whole-body MRI with diffusion imaging (WB-MRI-DWI) in multiple myeloma and lymphoma
Alessandro Stecco, Francesco Buemi, Antoine Iannessi, Alessandro Carriero & Andrea Gallamini
Pages: 2546-2556
Published online: 12 Feb 2018
AbstractforCurrent concepts in tumor imaging with whole-body MRI with diffusion imaging (WB-MRI-DWI) in multiple myeloma and lymphoma | Full Text | References | PDF (2.1 MB) | Supplemental
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Original Article: Clinical

Cardiotoxicity associated with carfilzomib: systematic review and meta-analysis
Chintan Shah, Rohit Bishnoi, Ankur Jain, Harini Bejjanki, Sican Xiong, Yu Wang, Fei Zou & Jan S. Moreb
Pages: 2557-2569
Published online: 21 Feb 2018
AbstractforCardiotoxicity associated with carfilzomib: systematic review and meta-analysis | Full Text | References | PDF (1.9 MB) | Supplemental
  • 1959 Views
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Decitabine in combination with G-CSF, low-dose cytarabine and aclarubicin is as effective as standard dose chemotherapy in the induction treatment for patients aged from 55 to 69 years old with newly diagnosed acute myeloid leukemia
Jiayu Huang, Ming Hong, Yu Zhu, Huihui Zhao, Xiaoyan Zhang, Yujie Wu, Yun Lian, Xiaoli Zhao, Jianyong Li & Sixuan Qian
Pages: 2570-2579
Published online: 04 Apr 2018
AbstractforDecitabine in combination with G-CSF, low-dose cytarabine and aclarubicin is as effective as standard dose chemotherapy in the induction treatment for patients aged from 55 to 69 years old with newly diagnosed acute myeloid leukemia | Full Text | References | PDF (1.2 MB) | Supplemental
  • 369 Views
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A retrospective, matched paired analysis comparing bendamustine containing BeEAM versus BEAM conditioning regimen: results from a single center experience
Khalil Saleh, Alina Danu, Serge Koscielny, Clémence Legoupil, Sylvain Pilorge, Cristina Castilla-Llorente, David Ghez, Julien Lazarovici, Jean-Marie Michot, Nadine Khalife-Saleh, Valerie Lapierre, Kamelia Alenxandrova, Julia Arfi-Rouche, Jean-Henri Bourhis & Vincent Ribrag
Pages: 2580-2587
Published online: 22 Nov 2017
AbstractforA retrospective, matched paired analysis comparing bendamustine containing BeEAM versus BEAM conditioning regimen: results from a single center experience | Full Text | References | PDF (690.2 KB) | Supplemental
  • 470 Views
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Phase 1 trial of ibrutinib and carfilzomib combination therapy for relapsed or relapsed and refractory multiple myeloma
Ajai Chari, Sarah Larson, Beata Holkova, Robert F. Cornell, Cristina Gasparetto, Chatchada Karanes, Jeffrey V. Matous, Ruben Niesvizky, Jason Valent, Matthew Lunning, Saad Z. Usmani, Larry D. Anderson Jr, Lipo Chang, Yihua Lee, Yvonne Pak, Zeena Salman, Thorsten Graef, Elizabeth Bilotti & Saurabh Chhabra
Pages: 2588-2594
Published online: 04 Apr 2018
AbstractforPhase 1 trial of ibrutinib and carfilzomib combination therapy for relapsed or relapsed and refractory multiple myeloma | Full Text | References | PDF (697.3 KB) | Supplemental
  • 3262 Views
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Open Access
A phase-1 study of dasatinib plus all-trans retinoic acid in acute myeloid leukemia
Robert L. Redner, Jan H. Beumer, Patricia Kropf, Mounzer Agha, Michael Boyiadzis, Kathleen Dorritie, Rafic Farah, Jing-Zhao Hou, Annie Im, Seah H. Lim, Anastasios Raptis, Alison Sehgal, Susan M. Christner, Daniel Normolle & Daniel E. Johnson
Pages: 2595-2601
Published online: 04 Apr 2018
AbstractforA phase-1 study of dasatinib plus all-trans retinoic acid in acute myeloid leukemia | Full Text | References | PDF (1.2 MB) | Supplemental
  • 2686 Views
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Venous thromboembolism in patients with non-Hodgkin lymphoma or chronic lymphocytic leukemia treated with lenalidomide: a systematic review
Marc Sorigue, Elisa Orna & Juan-Manuel Sancho
Pages: 2602-2611
Published online: 21 Mar 2018
AbstractforVenous thromboembolism in patients with non-Hodgkin lymphoma or chronic lymphocytic leukemia treated with lenalidomide: a systematic review | Full Text | References | PDF (879.6 KB) | Supplemental
  • 317 Views
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Long-term results of the AIEOP MH’96 childhood Hodgkin’s lymphoma trial and focus on significance of response to chemotherapy and its implication in low risk patients to avoid radiotherapy
Roberta Burnelli, Simona Rinieri, Roberto Rondelli, Alessandra Todesco, Maurizio Bianchi, Alberto Garaventa, Marco Zecca, Paolo Indolfi, Valentino Conter, Nicola Santoro, Maurizio Aricò, Simone Cesaro, Salvatore D’amico, Piero Farruggia, Raffaela De Santis, Franco Locatelli, Stefano A. Pileri, Giovanni Scarzello, Maurizio Mascarin, Vico Vecchi & On behalf of AIEOP (Italian Association of Pediatric Hematology and Oncology) and Pediatric Hodgkin’s Lymphoma working Group
Pages: 2612-2621
Published online: 16 Feb 2018
AbstractforLong-term results of the AIEOP MH’96 childhood Hodgkin’s lymphoma trial and focus on significance of response to chemotherapy and its implication in low risk patients to avoid radiotherapy | Full Text | References | PDF (971 KB) | Supplemental
  • 377 Views
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Diagnostic accuracy and interobserver agreement of contrast-enhanced ultrasound in the evaluation of residual lesions after treatment for malignant lymphoma and testicular cancer: a retrospective pilot study in 52 patients
Anke Peil-Grun, Corinna Trenker, Konrad Görg, Albrecht Neesse, Jörg Haasenritter & Christian Görg
Pages: 2622-2627
Published online: 27 Feb 2018
AbstractforDiagnostic accuracy and interobserver agreement of contrast-enhanced ultrasound in the evaluation of residual lesions after treatment for malignant lymphoma and testicular cancer: a retrospective pilot study in 52 patients | Full Text | References | PDF (1.2 MB) | Supplemental
  • 116 Views
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Original Article: Research

Role of Yin Yang-1 (YY1) in the transcription regulation of the multi-drug resistance (MDR1) gene
Gabriela Antonio-Andrés, Jesus Rangel-Santiago, Belen Tirado-Rodríguez, Gustavo U. Martinez-Ruiz, Miguel Klunder-Klunder, Mario I. Vega, Briceida Lopez-Martinez, Elva Jiménez-Hernández, Jose Torres Nava, Aurora Medina-Sanson & Sara Huerta-Yepez
Pages: 2628-2638
Published online: 04 Apr 2018
AbstractforRole of Yin Yang-1 (YY1) in the transcription regulation of the multi-drug resistance (MDR1) gene | Full Text | References | PDF (1.5 MB) | Supplemental
  • 266 Views
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Expression of TRIM28 correlates with proliferation and Bortezomib-induced apoptosis in B-cell non-Hodgkin lymphoma
Pei-Pei Zhang, Da-Zhi Ding, Bing Shi, Shu-Qing Zhang, Ling-Li Gu, Yu-Chan Wang & Chun Cheng
Pages: 2639-2649
Published online: 23 Mar 2018
AbstractforExpression of TRIM28 correlates with proliferation and Bortezomib-induced apoptosis in B-cell non-Hodgkin lymphoma | Full Text | References | PDF (3 MB) | Supplemental
  • 256 Views
  • 6 CrossRef citations
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Omitting cardiophrenic lymph nodes in the treatment of patients with Hodgkin lymphoma via modified involved-site radiation therapy
Chelsea C. Pinnix, Andrew Wirth, Sarah A. Milgrom, Therese Y. Andraos, Michalis Aristophanous, Mary Pham, Donald Hancock, Ethan B. Ludmir, Jillian R. Gunther, Michelle A. Fanale, Yasuhiro Oki, Loretta Nastoupil, Hubert H. Chuang, N. George Mikhaeel & Bouthaina S. Dabaja
Pages: 2650-2659
Published online: 04 Apr 2018
AbstractforOmitting cardiophrenic lymph nodes in the treatment of patients with Hodgkin lymphoma via modified involved-site radiation therapy | Full Text | References | PDF (1.8 MB) | Supplemental
  • 184 Views
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Oncogene-induced senescence: a potential breakpoint mechanism against malignant transformation in plasma cell disorders
Nicola Lehners, Elena Ellert, Jing Xu, Jens Hillengass, Jonas Leichsenring, Albrecht Stenzinger, Hartmut Goldschmidt, Mindaugas Andrulis & Marc S. Raab
Pages: 2660-2669
Published online: 04 Apr 2018
AbstractforOncogene-induced senescence: a potential breakpoint mechanism against malignant transformation in plasma cell disorders | Full Text | References | PDF (2.1 MB) | Supplemental
  • 214 Views
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Original Article: Clinical

Strong immunoexpression of dickkopf-1 is associated with response to bortezomib in multiple myeloma
Yong Won Choi, Joon Seong Park, Jae Ho Han, Jang-Hee Kim, Mi Sun Ahn, Hyun Woo Lee, Seok Yun Kang, Jin-Hyuk Choi & Seong Hyun Jeong
Pages: 2670-2678
Published online: 27 Mar 2018
AbstractforStrong immunoexpression of dickkopf-1 is associated with response to bortezomib in multiple myeloma | Full Text | References | PDF (1.7 MB) | Supplemental
  • 153 Views
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Original Article: Research

Salvage tigecycline in high risk febrile neutropenic patients with hematological malignancies: a prospective multicenter study
Xin-Ping Zhou, Xiu-Jin Ye, Jian-Ping Shen, Jian-Ping Lan, Hui-Fang Jiang, Jin Zhang, Xue-Jin Zhang, Li Li, Shen-Xian Qian & Hong-Yan Tong
Pages: 2679-2685
Published online: 16 Feb 2018
AbstractforSalvage tigecycline in high risk febrile neutropenic patients with hematological malignancies: a prospective multicenter study | Full Text | References | PDF (653.6 KB) | Supplemental
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Ibrutinib inhibits free fatty acid metabolism in chronic lymphocytic leukemia
Uri Rozovski, David M. Harris, Ping Li, Zhiming Liu, Preetesh Jain, Alessandra Ferrajoli, Jan Burger, Phillip Thompson, Nitin Jain, William Wierda, Michael J. Keating & Zeev Estrov
Pages: 2686-2691
Published online: 21 Feb 2018
AbstractforIbrutinib inhibits free fatty acid metabolism in chronic lymphocytic leukemia | Full Text | References | PDF (823 KB) | Supplemental
  • 444 Views
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Letter to the Editor

Navigating the changing multiple myeloma treatment landscape: clinical practice patterns of MM patients treated in- and outside German DSMM study group trials
Laura Gengenbach, Heike Reinhardt, Gabriele Ihorst, Stefanie Ajayi, Sandra Maria Dold, Martin Köhler, Hermann Einsele, Justus Duyster, Ralph Wäsch & Monika Engelhardt
Pages: 2692-2699
Published online: 23 Mar 2018
First Page PreviewforNavigating the changing multiple myeloma treatment landscape: clinical practice patterns of MM patients treated in- and outside German DSMM study group trials | Full Text | References | PDF (889.2 KB) | Supplemental
  • 307 Views
  • 15 CrossRef citations
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Comparative study on ATG-thymoglobulin versus ATG-fresenius for the graft-versus-host disease (GVHD) prophylaxis in allogeneic stem cell transplantation from matched unrelated donor: a single-centre experience over the contemporary years
Nicola Polverelli, Michele Malagola, Alessandro Turra, Cristina Skert, Simone Perucca, Marco Chiarini, Federica Cattina, Benedetta Rambaldi, Valeria Cancelli, Enrico Morello, Francesca Schieppati, Simona Bernardi, Camilla Zanaglio, Alessandra Sottini, Viviana Giustini, Luisa Imberti, Alessandro Montanelli & Domenico Russo
Pages: 2700-2705
Published online: 12 Mar 2018
First Page PreviewforComparative study on ATG-thymoglobulin versus ATG-fresenius for the graft-versus-host disease (GVHD) prophylaxis in allogeneic stem cell transplantation from matched unrelated donor: a single-centre experience over the contemporary years | Full Text | References | PDF (1 MB) | Supplemental
  • 619 Views
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Expression of a novel ZMYND11/MBTD1 fusion transcript in CD7+CD56+ acute myeloid leukemia with t(10;17)(p15;q21)
Katsuya Yamamoto, Kimikazu Yakushijin, Hiroya Ichikawa, Seiji Kakiuchi, Shinichiro Kawamoto, Hisayuki Matsumoto, Yuji Nakamachi, Jun Saegusa, Hiroshi Matsuoka & Hironobu Minami
Pages: 2706-2710
Published online: 18 Jun 2018
First Page PreviewforExpression of a novel ZMYND11/MBTD1 fusion transcript in CD7+CD56+ acute myeloid leukemia with t(10;17)(p15;q21) | Full Text | References | PDF (1 MB) | Supplemental
  • 194 Views
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Significant impact of immunosuppression on the incidence of secondary malignancies following fludarabine, cyclophosphamide, and rituximab (FCR) treatment in patients with indolent B-cell neoplasms
Nathalie Denizon, Alix Baugier de Materre, Mustapha Alani, Habib Ghnaya, Jonathan Farhi, Anne Besançon & Kamel Laribi
Pages: 2711-2714
Published online: 21 Mar 2018
First Page PreviewforSignificant impact of immunosuppression on the incidence of secondary malignancies following fludarabine, cyclophosphamide, and rituximab (FCR) treatment in patients with indolent B-cell neoplasms | Full Text | References | PDF (476.8 KB) | Supplemental
  • 181 Views
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Lymphomatoid granulomatosis and large granular lymphocyte leukemia, a rare association of two lymphoproliferative disorders
Giulia De Luca, Stefania Trasarti, Luisa Bizzoni, Ilaria del Giudice, Irene Della Starza, Maria Stefania De Propris, Giuseppe Gentile, Francesca Mancini, Sara Mantovani, Luigi Petrucci, Valentina Tabanelli, Anna Guarini, Marco Vignetti & Robin Foà
Pages: 2715-2718
Published online: 23 Feb 2018
First Page PreviewforLymphomatoid granulomatosis and large granular lymphocyte leukemia, a rare association of two lymphoproliferative disorders | Full Text | References | PDF (1.1 MB) | Supplemental
  • 142 Views
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Chronic graft versus host disease is associated with erectile dysfunction in allogeneic hematopoietic stem cell transplant patients: a single-center experience
Angelo Andreini, Nicola Zampieri, Claudio Costantini, Giovanni Malerba, Costanza Bruno, Gianluca Salvagno, Giuseppe Francia, Michele Gottardi, Michela Rimondini, Isacco Ferrarini, Giuseppe Lippi, Achille Ambrosetti, Fabio Benedetti & Cristina Tecchio
Pages: 2719-2722
Published online: 21 Mar 2018
First Page PreviewforChronic graft versus host disease is associated with erectile dysfunction in allogeneic hematopoietic stem cell transplant patients: a single-center experience | Full Text | References | PDF (375.7 KB) | Supplemental
  • 197 Views
  • 4 CrossRef citations
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Beliefs and practice patterns in hyperleukocytosis management in acute myeloid leukemia: a large U.S. web-based survey
Maximilian Stahl, Alexander Pine, Jeanne E. Hendrickson, Mark R. Litzow, Selina M. Luger, Richard M. Stone, Harry P. Erba, Tae Kon Kim, Mikkael A. Sekeres, David P. Steensma, Rami S. Komrokji, Steven D. Gore & Amer M. Zeidan
Pages: 2723-2726
Published online: 18 Apr 2018
First Page PreviewforBeliefs and practice patterns in hyperleukocytosis management in acute myeloid leukemia: a large U.S. web-based survey | Full Text | References | PDF (1.1 MB) | Supplemental
  • 326 Views
  • 15 CrossRef citations
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Allogeneic hematopoietic cell transplant for relapsed-refractory, marginal zone lymphoma: a single-center experience
Bhagirathbhai R. Dholaria, William A. Hammond, Vivek Roy, Taimur Sher, Prakash Vishnu, Aixa Soyano, Laura E. Finn & Han Tun
Pages: 2727-2730
Published online: 23 Mar 2018
First Page PreviewforAllogeneic hematopoietic cell transplant for relapsed-refractory, marginal zone lymphoma: a single-center experience | Full Text | References | PDF (813.5 KB) | Supplemental
  • 200 Views
  • 2 CrossRef citations
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Acute myeloid leukemia developed in Ph− cells with MLL gene amplification in a patient with chronic myelogenous leukemia
Jie-Gen Jiang, Yin Xu, Zhao Wu, Hongyu Ni & Eric X. Wei
Pages: 2731-2733
Published online: 23 Feb 2018
First Page PreviewforAcute myeloid leukemia developed in Ph− cells with MLL gene amplification in a patient with chronic myelogenous leukemia | Full Text | References | PDF (747.3 KB) | Supplemental
  • 95 Views
  • 1 CrossRef citations
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Feasibility and safety of therapy with ibrutinib after antiviral control of hepatitis B virus (HBV) reactivation in chronic lymphocytic leukemia patients
Stefano Molica, Luciano Levato, Rosanna Mirabelli, Alessanda Tedeschi & Mirella Lentini
Pages: 2734-2736
Published online: 21 Feb 2018
First Page PreviewforFeasibility and safety of therapy with ibrutinib after antiviral control of hepatitis B virus (HBV) reactivation in chronic lymphocytic leukemia patients | Full Text | References | PDF (443.3 KB) | Supplemental
  • 399 Views
  • 7 CrossRef citations
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Hypomethylating agents (HMAs) effect on myelodysplastic/myeloproliferative neoplasm unclassifiable (MDS/MPN-U): single institution experience
Aref Al-Kali, Ahmed Kamel Abou Hussein, Mrinal Patnaik, Darci Zblewski, Naseema Gangat, Shahrukh Hashmi, Michelle Elliott, William Hogan & Mark Litzow
Pages: 2737-2739
Published online: 21 Feb 2018
First Page PreviewforHypomethylating agents (HMAs) effect on myelodysplastic/myeloproliferative neoplasm unclassifiable (MDS/MPN-U): single institution experience | Full Text | References | PDF (750.8 KB) | Supplemental
  • 262 Views
  • 9 CrossRef citations
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An unusual, CD4 and CD8 dual-positive, CD25 negative, tumor cell phenotype in a patient with adult T-cell leukemia/lymphoma
Nicholas Casey, Hiroshi Fujiwara, Taichi Azuma, Yuichi Murakami, Makoto Yoshimitsu, Izumi Masamoto, Yuichiro Nawa, Jun Yamanouchi, Hiroshi Narumi, Yoshihiro Yakushijin, Takaaki Hato & Masaki Yasukawa
Pages: 2740-2742
Published online: 21 Feb 2018
First Page PreviewforAn unusual, CD4 and CD8 dual-positive, CD25 negative, tumor cell phenotype in a patient with adult T-cell leukemia/lymphoma | Full Text | References | PDF (593 KB) | Supplemental
  • 131 Views
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Elevated GLI3 expression in germinal center diffuse large B cell lymphoma
Weiguo Han, Gabriela Ibarra, Mamta Gupta, Yanbin Yin & Sherine F. Elsawa
Pages: 2743-2745
Published online: 21 Feb 2018
First Page PreviewforElevated GLI3 expression in germinal center diffuse large B cell lymphoma | Full Text | References | PDF (914.5 KB) | Supplemental
  • 134 Views
  • 3 CrossRef citations
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Efficacy of ibrutinib as first-line treatment of tumoral Bing–Neel syndrome
Laurys Boudin, Matthieu Patient, Emilie Roméo, Jean-Sébastien Bladé & Jean-Pierre de Jauréguiberry
Pages: 2746-2748
Published online: 23 Mar 2018
First Page PreviewforEfficacy of ibrutinib as first-line treatment of tumoral Bing–Neel syndrome | Full Text | References | PDF (575.4 KB) | Supplemental
  • 268 Views
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An abscopal effect may augment PD-1 inhibition in refractory classical Hodgkin lymphoma
Joel C. Wight, Eliza A. Hawkes, Salvatore U. Berlangieri, Richard Khor & Andrew P. Grigg
Pages: 2749-2751
Published online: 23 Mar 2018
First Page PreviewforAn abscopal effect may augment PD-1 inhibition in refractory classical Hodgkin lymphoma | Full Text | References | PDF (797.9 KB) | Supplemental
  • 229 Views
  • 10 CrossRef citations
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AML with MDS-related changes and blasts of mixed lineage: time for a new provisional entity?
Matthew M. Klairmont, Jinjun Cheng & Joel F. Gradowski
Pages: 2752-2754
Published online: 04 Apr 2018
First Page PreviewforAML with MDS-related changes and blasts of mixed lineage: time for a new provisional entity? | Full Text | References | PDF (885.6 KB) | Supplemental
  • 147 Views
  • 3 CrossRef citations
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Azacitidine effectively reduces TP53-mutant leukemic cell burden in secondary acute myeloid leukemia after cord blood transplantation
Tomomi Takei, Kazuaki Yokoyama, Eigo Shimizu, Takaaki Konuma, Satoshi Takahashi, Rui Yamaguchi, Seiya Imoto, Satoru Miyano & Arinobu Tojo
Pages: 2755-2756
Published online: 12 Apr 2018
CitationforAzacitidine effectively reduces TP53-mutant leukemic cell burden in secondary acute myeloid leukemia after cord blood transplantation | Full Text | References | PDF (342 KB) | Supplemental
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Correspondence

Rituximab addition to chemotherapy in real world patients with chronic lymphocytic leukemia: effective in first line but indication of lack of efficacy in subsequent lines of therapy
Lina van der Straten, Avinash G. Dinmohamed, Peter E. Westerweel, Anton W. Langerak, Jurgen Riedl, Jeanette K. Doorduijn, Arnon P. Kater & Mark-David Levin
Pages: 2757-2761
Published online: 04 Apr 2018
First Page PreviewforRituximab addition to chemotherapy in real world patients with chronic lymphocytic leukemia: effective in first line but indication of lack of efficacy in subsequent lines of therapy | Full Text | References | PDF (925.2 KB) | Supplemental
  • 219 Views
  • 1 CrossRef citations
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Corresondence

In reply to the letter to the editor regarding “Effect of initial body mass index on survival outcome of patients with myelodysplastic syndrome: a single-center retrospective study”
Jianhua Feng, Kang Yu & Xi Xu
Page: 2762
Published online: 17 Dec 2018
CitationforIn reply to the letter to the editor regarding “Effect of initial body mass index on survival outcome of patients with myelodysplastic syndrome: a single-center retrospective study” | Full Text | References | PDF (173.9 KB)
  • 35 Views
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