Leukemia & Lymphoma, Volume 59, Issue 4 (2018)

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Leukemia & Lymphoma, Volume 59, Issue 4 (2018)

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Commentary

Questioning the value of routine imaging for patients with mantle cell lymphoma in first remission
Tarec C. El-Galaly & Chan Yoon Cheah
Pages: 775-777
Published online: 22 Aug 2017
First Page PreviewforQuestioning the value of routine imaging for patients with mantle cell lymphoma in first remission | Full Text | References | PDF (310 KB) | Supplemental
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Reviews

TP53 in adult acute lymphoblastic leukemia
Silvia Salmoiraghi, Alessandro Rambaldi & Orietta Spinelli
Pages: 778-789
Published online: 06 Jul 2017
AbstractforTP53 in adult acute lymphoblastic leukemia | Full Text | References | PDF (1.2 MB) | Supplemental
  • 769 Views
  • 10 CrossRef citations
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The emerging role of immune checkpoint based approaches in AML and MDS
Prajwal Boddu, Hagop Kantarjian, Guillermo Garcia-Manero, James Allison, Padmanee Sharma & Naval Daver
Pages: 790-802
Published online: 06 Jul 2017
AbstractforThe emerging role of immune checkpoint based approaches in AML and MDS | Full Text | References | PDF (1.4 MB) | Supplemental
  • 2180 Views
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Myelodysplastic and myeloproliferative neoplasms: updates on the overlap syndromes
Swapna Thota & Aaron T. Gerds
Pages: 803-812
Published online: 03 Aug 2017
AbstractforMyelodysplastic and myeloproliferative neoplasms: updates on the overlap syndromes | Full Text | References | PDF (745.6 KB) | Supplemental
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Original Articles: Clinical

A phase I/II randomized trial of clofarabine or fludarabine added to idarubicin and cytarabine for adults with relapsed or refractory acute myeloid leukemia
Nicholas J. Short, Hagop Kantarjian, Farhad Ravandi, Xuelin Huang, Lianchun Xiao, Guillermo Garcia-Manero, William Plunkett, Varsha Gandhi, Koji Sasaki, Naveen Pemmaraju, Naval G. Daver, Gautam Borthakur, Nitin Jain, Marina Konopleva, Zeev Estrov, Tapan M. Kadia, William G. Wierda, Courtney D. DiNardo, Mark Brandt, Susan M. O’Brien, Jorge E. Cortes & Elias Jabbour
Pages: 813-820
Published online: 18 Jul 2017
AbstractforA phase I/II randomized trial of clofarabine or fludarabine added to idarubicin and cytarabine for adults with relapsed or refractory acute myeloid leukemia | Full Text | References | PDF (807.7 KB) | Supplemental
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CD25 expression and outcomes in older patients with acute myelogenous leukemia treated with plerixafor and decitabine
John N. Allan, Gail J. Roboz, Gulce Askin, Ellen Ritchie, Joseph Scandura, Paul Christos, Duane C. Hassane & Monica L. Guzman
Pages: 821-828
Published online: 18 Jul 2017
AbstractforCD25 expression and outcomes in older patients with acute myelogenous leukemia treated with plerixafor and decitabine | Full Text | References | PDF (912.9 KB) | Supplemental
  • 262 Views
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KIT mutations correlate with adverse survival in children with core-binding factor acute myeloid leukemia
Xi Chen, Hu Dou, Xingjuan Wang, Yi Huang, Ling Lu, Junqing Bin, Yongchun Su, Lin Zou, Jie Yu & Liming Bao
Pages: 829-836
Published online: 09 Aug 2017
AbstractforKIT mutations correlate with adverse survival in children with core-binding factor acute myeloid leukemia | Full Text | References | PDF (786.6 KB) | Supplemental
  • 355 Views
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Myeloablative busulfan/cytoxan conditioning versus reduced-intensity fludarabine/melphalan conditioning for allogeneic hematopoietic stem cell transplant in patients with acute myelogenous leukemia
Vishal Dhere, Scott Edelman, Edmund K. Waller, Amelia Langston, Michael Graiser, Erin C. Connolly, Jeffrey M. Switchenko, Natia Esiashvili & Mohammad K. Khan
Pages: 837-843
Published online: 07 Aug 2017
AbstractforMyeloablative busulfan/cytoxan conditioning versus reduced-intensity fludarabine/melphalan conditioning for allogeneic hematopoietic stem cell transplant in patients with acute myelogenous leukemia | Full Text | References | PDF (798 KB) | Supplemental
  • 362 Views
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MPN10 score and survival of molecularly annotated myeloproliferative neoplasm patients
Yasser H. ElNahass, Hossam K. Mahmoud, Mervat M. Mattar, Omar A. Fahmy, Mohamed A. Samra, Raafat M. Abdelfattah, Fatma A. ElRefaey, Hala M. Fahmy, Gamal M. Fathy, Ahmed Abdulgawad, Mohamed AbdelKader, Hend N. Elleithy, Mona Gamil, Mohamed Talaat, Heba A. Nader & Wafaa H. ElMetnawy
Pages: 844-854
Published online: 22 Aug 2017
AbstractforMPN10 score and survival of molecularly annotated myeloproliferative neoplasm patients | Full Text | References | PDF (1.8 MB) | Supplemental
  • 503 Views
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Acute central nervous system complications and ammonium levels in adult patients with acute lymphoblastic leukemia receiving l-asparaginase
Nicole Strickler, Stefan Balabanov, Katharina Casauro, Urs Schanz, Markus G. Manz & Bernhard Gerber
Pages: 855-862
Published online: 21 Jul 2017
AbstractforAcute central nervous system complications and ammonium levels in adult patients with acute lymphoblastic leukemia receiving l-asparaginase | Full Text | References | PDF (742.2 KB) | Supplemental
  • 345 Views
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Phase-I and randomized phase-II trial of panobinostat in combination with ICE (ifosfamide, carboplatin, etoposide) in relapsed or refractory classical Hodgkin lymphoma
Bei Hu, Anas Younes, Jason R. Westin, Francesco Turturro, Linda Claret, Lei Feng, Nathan Fowler, Sattva Neelapu, Jorge Romaguera, Fredrick B. Hagemeister, Maria Alma Rodriguez, Felipe Samaniego, Luis E. Fayad, Amanda R. Copeland, Loretta J. Nastoupil, Yago Nieto, Michelle A. Fanale & Yasuhiro Oki
Pages: 863-870
Published online: 09 Aug 2017
AbstractforPhase-I and randomized phase-II trial of panobinostat in combination with ICE (ifosfamide, carboplatin, etoposide) in relapsed or refractory classical Hodgkin lymphoma | Full Text | References | PDF (944.8 KB) | Supplemental
  • 465 Views
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Exposure-response evaluations of venetoclax efficacy and safety in patients with non-Hodgkin lymphoma
Apurvasena Parikh, Sathej Gopalakrishnan, Kevin J. Freise, Maria E. Verdugo, Rajeev M. Menon, Sven Mensing & Ahmed Hamed Salem
Pages: 871-879
Published online: 10 Aug 2017
AbstractforExposure-response evaluations of venetoclax efficacy and safety in patients with non-Hodgkin lymphoma | Full Text | References | PDF (1.5 MB) | Supplemental
  • 666 Views
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Responses to romidepsin in patients with cutaneous T-cell lymphoma and prior treatment with systemic chemotherapy
Madeleine Duvic, Susan E. Bates, Richard Piekarz, Robin Eisch, Youn H. Kim, Adam Lerner, Tadeusz Robak, Alexey Samtsov, Jürgen C. Becker, William McCulloch, Joel Waksman & Sean Whittaker
Pages: 880-887
Published online: 30 Aug 2017
AbstractforResponses to romidepsin in patients with cutaneous T-cell lymphoma and prior treatment with systemic chemotherapy | Full Text | References | PDF (1,003.4 KB) | Supplemental
  • 2567 Views
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Open Access
Surveillance imaging in mantle cell lymphoma in first remission lacks clinical utility
Daniel M. Guidot, Jeffrey M. Switchenko, Loretta J. Nastoupil, Jean L. Koff, Kristie A. Blum, Joseph Maly, Christopher R. Flowers & Jonathon B. Cohen
Pages: 888-895
Published online: 10 Aug 2017
AbstractforSurveillance imaging in mantle cell lymphoma in first remission lacks clinical utility | Full Text | References | PDF (1.1 MB) | Supplemental
  • 269 Views
  • 10 CrossRef citations
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Efficacy and safety of frontline rituximab, cyclophosphamide, doxorubicin and prednisone plus bortezomib (VR-CAP) or vincristine (R-CHOP) in a subset of newly diagnosed mantle cell lymphoma patients medically eligible for transplantation in the randomized, phase 3 LYM-3002 study
Johannes Drach, Huiqiang Huang, Olga Samoilova, Andrew Belch, Charles Farber, André Bosly, Jan Novak, Jan Zaucha, Angela Dascalescu, Udomsak Bunworasate, Zvenyslava Masliak, Kateryna Vilchevskaya, Tadeusz Robak, Lixia Pei, Brendan Rooney, Helgi van de Velde & Franco Cavalli
Pages: 896-903
Published online: 17 Jan 2018
AbstractforEfficacy and safety of frontline rituximab, cyclophosphamide, doxorubicin and prednisone plus bortezomib (VR-CAP) or vincristine (R-CHOP) in a subset of newly diagnosed mantle cell lymphoma patients medically eligible for transplantation in the randomized, phase 3 LYM-3002 study | Full Text | References | PDF (966 KB) | Supplemental
  • 2858 Views
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Open Access
The effect of R-CHOP dose reduction on overall survival of elderly patients with DLBCL – comparative study
Liat Vidal, Shany Lando, Iuliana Vaxman, Tzippy Shochat, Pia Raanani, Ronit Gurion & Anat Gafter-Gvili
Pages: 904-910
Published online: 22 Aug 2017
AbstractforThe effect of R-CHOP dose reduction on overall survival of elderly patients with DLBCL – comparative study | Full Text | References | PDF (839.6 KB) | Supplemental
  • 491 Views
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Prevalence of cutaneous viral infections in incident cutaneous squamous cell carcinoma detected among chronic lymphocytic leukemia and hematopoietic stem cell transplant patients
Shalaka S. Hampras, Frederick L. Locke, Julio C. Chavez, Nishit S. Patel, Anna R. Giuliano, Kyle Miller, Tarik Gheit, Massimo Tommasino & Dana E. Rollison
Pages: 911-917
Published online: 06 Jul 2017
AbstractforPrevalence of cutaneous viral infections in incident cutaneous squamous cell carcinoma detected among chronic lymphocytic leukemia and hematopoietic stem cell transplant patients | Full Text | References | PDF (789 KB) | Supplemental
  • 336 Views
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Original Articles: Research

SH3BGRL as a novel prognostic biomarker is down-regulated in acute myeloid leukemia
Limei Xu, Mingming Zhang, Hui Li, Wen Guan, Bin Liu, Fengqi Liu, Hehua Wang, Juan Li, Shulan Yang, Xiuzhen Tong & Haihe Wang
Pages: 918-930
Published online: 06 Jul 2017
AbstractforSH3BGRL as a novel prognostic biomarker is down-regulated in acute myeloid leukemia | Full Text | References | PDF (3.5 MB) | Supplemental
  • 402 Views
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Identification of potential ibrutinib combinations in hematological malignancies using a combination high-throughput screen
Michael Schaffer, Shalini Chaturvedi, Cuc Davis, Regina Aquino, Emily Stepanchick, Matthias Versele, Yang Liu, Jennifer Yang, Rongzhen Lu & Sriram Balasubramanian
Pages: 931-940
Published online: 28 Jul 2017
AbstractforIdentification of potential ibrutinib combinations in hematological malignancies using a combination high-throughput screen | Full Text | References | PDF (1.5 MB) | Supplemental
  • 5348 Views
  • 23 CrossRef citations
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Open Access
Economic burden of multiple myeloma among patients in successive lines of therapy in the United States
Joanna P. MacEwan, Katharine Batt, Wes Yin, Desi Peneva, Steve Sison, Seanna Vine & Clara Chen
Pages: 941-949
Published online: 13 Aug 2017
AbstractforEconomic burden of multiple myeloma among patients in successive lines of therapy in the United States | Full Text | References | PDF (881.8 KB) | Supplemental
  • 1120 Views
  • 30 CrossRef citations
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The diverse expression of the WT1 gene in patients with acquired bone marrow failure syndromes
Yahong You, Jiali Huo, Shihong Lu, Yingqi Shao, Meili Ge, Jun Shi, Xingxin Li, Jinbo Huang, Zhendong Huang, Jing Zhang, Min Wang, Neng Nie & Yizhou Zheng
Pages: 950-957
Published online: 21 Jul 2017
AbstractforThe diverse expression of the WT1 gene in patients with acquired bone marrow failure syndromes | Full Text | References | PDF (830.4 KB) | Supplemental
  • 291 Views
  • 2 CrossRef citations
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Quantification of marrow hematogones following autologous stem cell transplant in adult patients with plasma cell myeloma or diffuse large B-cell lymphoma and correlation with outcome
Victor Santiago, Aleksandr Lazaryan, Brian McClune, Robert W. McKenna & Elizabeth L. Courville
Pages: 958-966
Published online: 21 Jul 2017
AbstractforQuantification of marrow hematogones following autologous stem cell transplant in adult patients with plasma cell myeloma or diffuse large B-cell lymphoma and correlation with outcome | Full Text | References | PDF (1.9 MB) | Supplemental
  • 287 Views
  • 3 CrossRef citations
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The initial level of MLL-partial tandem duplication affects the clinical outcomes in patients with acute myeloid leukemia
Jun Kong, Xiao-Su Zhao, Ya-Zhen Qin, Hong-Hu Zhu, Jin-Song Jia, Qian Jiang, Jing Wang, Ting Zhao, Xiao-Jun Huang & Hao Jiang
Pages: 967-972
Published online: 26 Jul 2017
AbstractforThe initial level of MLL-partial tandem duplication affects the clinical outcomes in patients with acute myeloid leukemia | Full Text | References | PDF (744.5 KB) | Supplemental
  • 460 Views
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Letters to the Editor

Sorted peripheral blood cells identify CALR mutations in B- and T-lymphocytes
Lasse Kjaer, Morten O. Holmström, Sabrina Cordua, Mads Hald Andersen, Inge Marie Svane, Mads Thomassen, Torben A Kruse, Niels Pallisgaard, Vibe Skov & Hans C. Hasselbalch
Pages: 973-977
Published online: 09 Aug 2017
First Page PreviewforSorted peripheral blood cells identify CALR mutations in B- and T-lymphocytes | Full Text | References | PDF (606.8 KB) | Supplemental
  • 268 Views
  • 15 CrossRef citations
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Selection and characterization of antibody clones are critical for accurate flow cytometry-based monitoring of CD123 in acute myeloid leukemia
Nicole M. Cruz, Mayumi Sugita, Nathan Ewing-Crystal, Linda Lam, Roman Galetto, Agnes Gouble, Julianne Smith, Duane C. Hassane, Gail J. Roboz & Monica L. Guzman
Pages: 978-982
Published online: 10 Aug 2017
First Page PreviewforSelection and characterization of antibody clones are critical for accurate flow cytometry-based monitoring of CD123 in acute myeloid leukemia | Full Text | References | PDF (1.1 MB) | Supplemental
  • 453 Views
  • 11 CrossRef citations
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Coexistence of leishmaniasis and multiple myeloma in the era of monoclonal antibody (anti-CD38 or anti-SLAMF7) containing triplets: one shared story of two exceptional cases
Dimitrios C. Ziogas, Evangelos Terpos, Maria Gavriatopoulou, Magdalini Migkou, Despoina Fotiou, Maria Roussou, Nikolaos Kanellias, Ioanna Tatouli, Evangelos Eleutherakis-Papaiakovou, Ioannis Panagiotidis, Ioannis Ntanasis-Stathopoulos, Efstathios Kastritis & Meletios A. Dimopoulos
Pages: 983-987
Published online: 07 Aug 2017
First Page PreviewforCoexistence of leishmaniasis and multiple myeloma in the era of monoclonal antibody (anti-CD38 or anti-SLAMF7) containing triplets: one shared story of two exceptional cases | Full Text | References | PDF (868.4 KB) | Supplemental
  • 234 Views
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Early infectious complications among patients treated with induction compared to hypomethylating therapy for acute myeloid leukemia
Marla M. Jalbut, Andrew M. Brunner, Philip C. Amrein, Karen K. Ballen, Gabriela S. Hobbs, Ashley M. Perry, Christelle P. Joseph & Amir T. Fathi
Pages: 988-991
Published online: 09 Aug 2017
First Page PreviewforEarly infectious complications among patients treated with induction compared to hypomethylating therapy for acute myeloid leukemia | Full Text | References | PDF (485.6 KB) | Supplemental
  • 183 Views
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Comprehensive genomic characterization dissects the complex biology of a case of synchronous Burkitt lymphoma and myeloid malignancy with shared hematopoietic ancestry
Georgina L. Ryland, Kate Jones, Michelle McBean, Amit Khot, John Francis Seymour & Piers Blombery
Pages: 992-995
Published online: 09 Aug 2017
First Page PreviewforComprehensive genomic characterization dissects the complex biology of a case of synchronous Burkitt lymphoma and myeloid malignancy with shared hematopoietic ancestry | Full Text | References | PDF (584.5 KB) | Supplemental
  • 129 Views
  • 2 CrossRef citations
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A novel t(3;9)(q21.2; p24.3) associated with SMARCA2 and ZNF148 genes rearrangement in myelodysplastic syndrome
Nicoletta Coccaro, Claudia Brunetti, Giuseppina Tota, Ciro Leo Pierri, Luisa Anelli, Antonella Zagaria, Paola Casieri, Luciana Impera, Crescenzio F. Minervini, Angela Minervini, Cosimo Cumbo, Alessandra Ricco, Paola Carluccio, Paola Orsini, Giorgina Specchia & Francesco Albano
Pages: 996-999
Published online: 18 Jul 2017
First Page PreviewforA novel t(3;9)(q21.2; p24.3) associated with SMARCA2 and ZNF148 genes rearrangement in myelodysplastic syndrome | Full Text | References | PDF (1.1 MB) | Supplemental
  • 166 Views
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Alloimmune hemolysis due to major RhE incompatibility after unrelated cord blood transplantation
Masamichi Isobe, Takaaki Konuma, Yuka Abe-Wada, Kyoko Hirata, Kazuo Ogami, Seiko Kato, Maki Oiwa-Monna, Susumu Tanoue, Tokiko Nagamura-Inoue, Satoshi Takahashi & Arinobu Tojo
Pages: 1000-1003
Published online: 20 Jul 2017
First Page PreviewforAlloimmune hemolysis due to major RhE incompatibility after unrelated cord blood transplantation | Full Text | References | PDF (438.4 KB) | Supplemental
  • 205 Views
  • 2 CrossRef citations
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Unexpected Pneumocystis jirovecii pneumonia in patients with untreated chronic lymphocytic leukemia
Lucile Sesé, Elisabeth Rivaud, Camille Bron, Véronique Leblond, Emmanuel Raffoux, Elisabeth Longchampt, Pierre Cahen, Leila Zemoura, François Mellot, Louis-Jean Couderc, Emilie Catherinot & on behalf of the Foch Hospital Lung Immune Deficiencies study group
Pages: 1004-1007
Published online: 03 Aug 2017
First Page PreviewforUnexpected Pneumocystis jirovecii pneumonia in patients with untreated chronic lymphocytic leukemia | Full Text | References | PDF (733.6 KB) | Supplemental
  • 156 Views
  • 3 CrossRef citations
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Trametinib for the treatment of IGHV4-34, MAP2K1-mutant variant hairy cell leukemia
Leslie A. Andritsos, Nicole R. Grieselhuber, Mirela Anghelina, Kerry A. Rogers, Sameek Roychowdhury, Julie W. Reeser, Cynthia D. Timmers, Aharon G. Freud, James S. Blachly, David M. Lucas, Gerard Lozanski, Jeffrey A. Jones, Katie Williams, Christopher Oakes, Dan Jones & Michael R. Grever
Pages: 1008-1011
Published online: 18 Sep 2017
First Page PreviewforTrametinib for the treatment of IGHV4-34, MAP2K1-mutant variant hairy cell leukemia | Full Text | References | PDF (700.5 KB) | Supplemental
  • 514 Views
  • 24 CrossRef citations
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Time to response and survival in hypomethylating agent-treated acute myeloid leukemia
Prajwal Boddu, Hagop Kantarjian, Guillermo Garcia-Manero, Farhad Ravandi, Elias Jabbour, Gautam Borthakur, Naval Daver, Naveen Pemmaraju, Sherry Pierce, Jorge Cortes & Tapan M. Kadia
Pages: 1012-1015
Published online: 25 Aug 2017
First Page PreviewforTime to response and survival in hypomethylating agent-treated acute myeloid leukemia | Full Text | References | PDF (772.5 KB) | Supplemental
  • 235 Views
  • 3 CrossRef citations
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Association between proteomic profile and molecular response in chronic myeloid leukemia patients
Vito Michele Garrisi, Nicola Sgherza, Massimo Breccia, Angela Iacobazzi, Giacoma De Tullio, Giovanni Nardelli, Antonio Negri, Rosa Divella, Antonella Daniele, Giuseppina Micelli, Antonio Tufaro, Nicola Cascavilla, Eufemia Savino, Ines Abbate & Attilio Guarini
Pages: 1016-1018
Published online: 11 Jul 2017
First Page PreviewforAssociation between proteomic profile and molecular response in chronic myeloid leukemia patients | Full Text | References | PDF (433.5 KB) | Supplemental
  • 117 Views
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Rituximab subcutaneous in B-cell non-Hodgkin lymphoma: clinical experience in a single center
Blanca Sanchez-Gonzalez, Elena Torres, Mariana Paola Ferraro Rosset, Montserrat Calafell, Carmen Gale, Laia Martinez, Esther Sancho, Pilar Garcia, Eva Gimeno, Francesc Garcia-Pallarols & Antonio Salar
Pages: 1019-1021
Published online: 21 Jul 2017
First Page PreviewforRituximab subcutaneous in B-cell non-Hodgkin lymphoma: clinical experience in a single center | Full Text | References | PDF (396 KB) | Supplemental
  • 285 Views
  • 3 CrossRef citations
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ETV6 and NOTCH1 germline variants in adult acute leukemia
Vaidas Dirse, Rimvydas Norvilas, Egle Gineikiene, Rėda Matuzevičienė, Laimonas Griskevicius & Egle Preiksaitiene
Pages: 1022-1024
Published online: 04 Aug 2017
First Page PreviewforETV6 and NOTCH1 germline variants in adult acute leukemia | Full Text | References | PDF (344 KB) | Supplemental
  • 345 Views
  • 7 CrossRef citations
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False-positive pregnancy tests in females of reproductive potential receiving lenalidomide in the United States
Carmen Castaneda, Neil Minton, Melinda Mezo, Damien Hirsch, Lisa Phillips, Paul Sheehan, Robin McWilliams, May Chan-Liston, Robert Bwire & John Freeman
Pages: 1025-1026
Published online: 09 Aug 2017
CitationforFalse-positive pregnancy tests in females of reproductive potential receiving lenalidomide in the United States | Full Text | References | PDF (287.6 KB) | Supplemental
  • 1355 Views
  • 1 CrossRef citations
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