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Original Articles

Plants containing pyrrolizidine alkaloids: toxicity and problems

Pages 282-292 | Received 07 May 2010, Accepted 15 Nov 2010, Published online: 25 Feb 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (21)

Ana Catarina Sousa, Cláudia Ribeiro, Virgínia M.F. Gonçalves, Inês Pádua & Sandra Leal. (2023) Chromatographic Methods for Detection and Quantification of Pyrrolizidine Alkaloids in Flora, Herbal Medicines, and Food: An Overview. Critical Reviews in Analytical Chemistry 0:0, pages 1-25.
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Fenja Klevenhusen, Anja These, Julian Taenzer, Kirsten Weiß & Robert Pieper. (2022) Effects of ensiling conditions on pyrrolizidine alkaloid degradation in silages mixed with two different Senecio spp.. Archives of Animal Nutrition 76:2, pages 93-111.
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Patrick P.J. Mulder, Mirjam D. Klijnstra, Roselinde M.A. Goselink, Ad M. van Vuuren, John W. Cone, Geert Stoopen & Ron L.A.P. Hoogenboom. (2020) Transfer of pyrrolizidine alkaloids from ragwort, common groundsel and viper’s bugloss to milk from dairy cows. Food Additives & Contaminants: Part A 37:11, pages 1906-1921.
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Ewelina Kowalczyk & Krzysztof Kwiatek. (2020) Application of the sum parameter method for the determination of pyrrolizidine alkaloids in teas. Food Additives & Contaminants: Part A 37:4, pages 622-633.
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Sajjad Ahmad, Farhat Ullah, Muhammad Ayaz, Ashfaq Ahmad, Abdul Sadiq & Syed Nadeem-Ul-Hassan Mohani. (2019) Nutritional and medicinal aspects of Rumex hastatus D. Don along with in vitro anti-diabetic activity. International Journal of Food Properties 22:1, pages 1733-1748.
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Christina Kast, Verena Kilchenmann, Hans Reinhard, Benoit Droz, Matteo Angelo Lucchetti, Arne Dübecke, Gudrun Beckh & Otmar Zoller. (2018) Chemical fingerprinting identifies Echium vulgare, Eupatorium cannabinum and Senecio spp. as plant species mainly responsible for pyrrolizidine alkaloids in bee-collected pollen. Food Additives & Contaminants: Part A 35:2, pages 316-327.
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G Cuce, HT Canbaz, ME Sozen, FH Yerlikaya & S Kalkan. (2017) Vitamin E and selenium treatment of monocrotaline induced hepatotoxicity in rats. Biotechnic & Histochemistry 92:1, pages 59-67.
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A. Eller & R. Chizzola. (2016) Seasonal variability in pyrrolizidine alkaloids in Senecio inaequidens from the Val Venosta (Northern Italy). Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology 150:6, pages 1306-1312.
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Elizabeth M. Mudge, A. Maxwell P. Jones & Paula N. Brown. (2015) Quantification of pyrrolizidine alkaloids in North American plants and honey by LC-MS: single laboratory validation. Food Additives & Contaminants: Part A 32:12, pages 2068-2074.
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Bart Huybrechts & Alfons Callebaut. (2015) Pyrrolizidine alkaloids in food and feed on the Belgian market. Food Additives & Contaminants: Part A 32:11, pages 1939-1951.
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Anely Nedelcheva, Nadezhda Kostova & Atanas Sidjimov. (2015) Pyrrolizidine alkaloids in Tussilago farfara from Bulgaria. Biotechnology & Biotechnological Equipment 29:sup1, pages S1-S7.
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Caroline T. Griffin, Simon M. Mitrovic, Martin Danaher & Ambrose Furey. (2015) Development of a fast isocratic LC-MS/MS method for the high-throughput analysis of pyrrolizidine alkaloids in Australian honey. Food Additives & Contaminants: Part A 32:2, pages 214-228.
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Caroline T. Griffin, Francesca Gosetto, Martin Danaher, Stefano Sabatini & Ambrose Furey. (2014) Investigation of targeted pyrrolizidine alkaloids in traditional Chinese medicines and selected herbal teas sourced in Ireland using LC-ESI-MS/MS. Food Additives & Contaminants: Part A 31:5, pages 940-961.
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Monique de Nijs, Ingrid J.W. Elbers & Patrick P.J. Mulder. (2014) Inter-laboratory comparison study for pyrrolizidine alkaloids in animal feed using spiked and incurred material. Food Additives & Contaminants: Part A 31:2, pages 288-299.
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Thaise L. Teixeira, Samuel Cota Teixeira, Claudio Vieira da Silva & Maria A. de. Souza. (2014) Potential therapeutic use of herbal extracts in trypanosomiasis. Pathogens and Global Health 108:1, pages 30-36.
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Anita Varga & Birgit Puschner. (2012) Retrospective study of cattle poisonings in California: recognition, diagnosis, and treatment. Veterinary Medicine: Research and Reports 3, pages 111-127.
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Hemlata Tamta, Rahul S. Pawar, Wayne G. Wamer, Erich Grundel, Alexander J. Krynitsky & Jeanne I. Rader. (2012) Comparison of metabolism-mediated effects of pyrrolizidine alkaloids in a HepG2/C3A cell-S9 co-incubation system and quantification of their glutathione conjugates. Xenobiotica 42:10, pages 1038-1048.
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Michael Boppré. (2011) The ecological context of pyrrolizidine alkaloids in food, feed and forage: an overview. Food Additives & Contaminants: Part A 28:3, pages 260-281.
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R.J. Molyneux, D.L. Gardner, S.M. Colegate & J.A. Edgar. (2011) Pyrrolizidine alkaloid toxicity in livestock: a paradigm for human poisoning?. Food Additives & Contaminants: Part A 28:3, pages 293-307.
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