Citations (624)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (35)
E Orecchini, ML Belladonna, MT Pallotta, C Volpi, L Zizi, E Panfili, M Gargaro, F Fallarino, S Rossini, C Suvieri, A Macchiarulo, S Bicciato, G Mondanelli & C Orabona. (2023) The signaling function of IDO1 incites the malignant progression of mouse B16 melanoma. OncoImmunology 12:1.
Read now
Read now
Ji Kwan Park, Laura C. Huang & Andrea L. Kossler. (2023) Erdheim–Chester disease and vemurafenib: a review of ophthalmic presentations and clinical outcomes. Orbit 42:3, pages 233-244.
Read now
Read now
Yafeng Tian, Mi Zhang, Panpan Heng, Hua Hou & Baoshan Wang. (2023) Pharmacophore-based virtual screening, molecular docking and molecular dynamics simulation for identification of potential ERK inhibitors. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-9.
Read now
Read now
Fabian Frontzek, Stephan Hailfinger & Georg Lenz. (2023) Plasmablastic lymphoma: from genetics to treatment. Leukemia & Lymphoma 64:4, pages 799-807.
Read now
Read now
Namood-e Sahar, Javeria Qadir, Syeda Kiran Riaz, Aimen Sultan, Aiza Arif & Muhammad Faraz Arshad Malik. (2022) Dysregulation of core circadian genes, BMAL1 and CLOCK, in colorectal cancer. Biological Rhythm Research 53:9, pages 1400-1413.
Read now
Read now
Udhaya Kumar. S, Bithia. R, Thirumal Kumar. D, C. George Priya Doss & Hatem Zayed. (2022) Mutational landscape of K-Ras substitutions at 12th position-a systematic molecular dynamics approach. Journal of Biomolecular Structure and Dynamics 40:4, pages 1571-1585.
Read now
Read now
Zhibing Lu, Hui Peng, Ruijuan Li, Xinyan Xu & Jiyong Peng. (2022) BarH-like homeobox 2 represses the transcription of keratin 16 and affects Ras signaling pathway to suppress nasopharyngeal carcinoma progression. Bioengineered 13:2, pages 3122-3136.
Read now
Read now
Bashir Ahmad, Yaser Gamallat, Muhammad Fiaz Khan, Syed Riaz Din, Muhammad Israr, Manzoor Ahmad, Naeem Tahir, Nasir Azam, Khalil Ur Rahman, Wang Xin, Wang Zexu, Peng Linjie, Pengyu Su & Wang Liang. (2021) Natural Polyphyllins (I, II, D, VI, VII) Reverses Cancer Through Apoptosis, Autophagy, Mitophagy, Inflammation, and Necroptosis. OncoTargets and Therapy 14, pages 1821-1841.
Read now
Read now
Elisha J Fogel, Avishai Samouha, Sanjay Goel & Radhashree Maitra. (2021) Transcriptome Signature of Immune Cells Post Reovirus Treatment in KRAS Mutated Colorectal Cancer. Cancer Management and Research 13, pages 6743-6754.
Read now
Read now
Cailong Zhang, Na Na, Li Liu & Yingzhu Qiu. (2021) CircRNA hsa_circ_0005909 Promotes Cell Proliferation of Osteosarcoma Cells by Targeting miR-338-3p/HMGA1 Axis. Cancer Management and Research 13, pages 795-803.
Read now
Read now
Connor Chestnut, Dharmalingam Subramaniam, Prasad Dandawate, Subhash Padhye, John Taylor$suffix/text()$suffix/text(), Scott Weir & Shrikant Anant. (2021) Targeting Major Signaling Pathways of Bladder Cancer with Phytochemicals: A Review. Nutrition and Cancer 73:11-12, pages 2249-2271.
Read now
Read now
Cheng Wang, Miaomiao Yang, Xi Gu & Yanjing Gu. (2021) Lemur tyrosine kinase-3 (LMTK3) induces chemoresistance to cetuximab in colorectal cancer via the ERK/MAPK pathway. Bioengineered 12:1, pages 6594-6605.
Read now
Read now
Bhuwan Prasad Awasthi, Prakash Chaudhary, Diwakar Guragain, Jun-Goo Jee, Jung-Ae Kim & Byeong-Seon Jeong. (2021) Synthesis and anti-hepatocellular carcinoma activity of aminopyridinol–sorafenib hybrids. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 1884-1897.
Read now
Read now
Adriana Diaconu, Bogdan-Ioan Coculescu, Gheorghe Manole, Horațiu Vultur, Elena Claudia Coculescu, Cristina Maria Stocheci, Ioan-Sorin Tudorache, Alexandra-Ligia Dincă & Valeriu Gabi Dincă. (2021) Lipoprotein-associated phospholipase A2 (Lp-PLA2) – possible diagnostic and risk biomarker in chronic ischaemic heart disease. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 68-73.
Read now
Read now
Yiling Yang, Qiang Zhou, Huiwen Pan, Liming Wang & Cheng Qian. (2020) Association Study of MAP3K1 SNPs and Risk Factors with Susceptibility to Esophageal Squamous Cell Carcinoma in a Chinese Population: A Case–Control Study. Pharmacogenomics and Personalized Medicine 13, pages 189-197.
Read now
Read now
Pengyu Su, Bashir Ahmad, Kun Zou & Lijuan Zou. (2020) β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways. OncoTargets and Therapy 13, pages 5207-5222.
Read now
Read now
Bashir Ahmad, Suliman Khan, Yang Liu, Mengzhou Xue, Ghulam Nabi, Sunjeet Kumar, Mohammed Alshwmi & Abdul Wakeel Qarluq. (2020) Molecular Mechanisms of Anticancer Activities of Puerarin. Cancer Management and Research 12, pages 79-90.
Read now
Read now
Bashir Ahmad, Suliman Khan, Ghulam Nabi, Yaser Gamallat, Pengyu Su, Yazeed Jamalat, Pengfei Duan & Lunguang Yao. (2019) Natural gypenosides: targeting cancer through different molecular pathways. Cancer Management and Research 11, pages 2287-2297.
Read now
Read now
Jin Wang, Xiao-Fan Yu, Nan OUYang, Qiulin Luo, Jian Tong, Tao Chen & Jianxiang Li. (2019) Role of DNA methylation regulation of miR-130b expression in human lung cancer using bioinformatics analysis. Journal of Toxicology and Environmental Health, Part A 82:17, pages 935-943.
Read now
Read now
Saeideh Nakhaei-Rad, Fereshteh Haghighi, Parivash Nouri, Soheila Rezaei Adariani, Jana Lissy, Neda S. Kazemein Jasemi, Radovan Dvorsky & Mohammad Reza Ahmadian. (2018) Structural fingerprints, interactions, and signaling networks of RAS family proteins beyond RAS isoforms. Critical Reviews in Biochemistry and Molecular Biology 53:2, pages 130-156.
Read now
Read now
Jinhui Wang, Wei Wang, Jichen Li, Liji Wu, Mei Song & Qinggang Meng. (2017) miR182 activates the Ras–MEK–ERK pathway in human oral cavity squamous cell carcinoma by suppressing RASA1 and SPRED1. OncoTargets and Therapy 10, pages 667-679.
Read now
Read now
Seung Cheol Kim, Boyun Choi & Youngjoo Kwon. (2017) Thiol-reducing agents prevent sulforaphane-induced growth inhibition in ovarian cancer cells. Food & Nutrition Research 61:1.
Read now
Read now
Ying Liu, Ran Ni, Hui Zhang, Lijun Miao, Jing Wang, Wenqing Jia & Yuanyuan Wang. (2016) Identification of feature genes for smoking-related lung adenocarcinoma based on gene expression profile data. OncoTargets and Therapy 9, pages 7397-7407.
Read now
Read now
Franciszek Sączewski, Anita Kornicka & Łukasz Balewski. (2016) Imidazoline scaffold in medicinal chemistry: a patent review (2012–2015). Expert Opinion on Therapeutic Patents 26:9, pages 1031-1048.
Read now
Read now
Qiankun Li, Yan Chen, Kui Ma, Along Zhao, Cuiping Zhang & Xiaobing Fu. (2016) Regenerative and reparative effects of human chorion-derived stem cell conditioned medium on photo-aged epidermal cells. Cell Cycle 15:8, pages 1144-1155.
Read now
Read now
Philip J. Uren, Emad Bahrami-Samani, Patricia Rosa de Araujo, Christine Vogel, Mei Qiao, Suzanne C. Burns, Andrew D. Smith & Luiz O. F. Penalva. (2016) High-throughput analyses of hnRNP H1 dissects its multi-functional aspect. RNA Biology 13:4, pages 400-411.
Read now
Read now
Cristiana Tanase, Radu Albulescu & Monica Neagu. (2016) Proteomic Approaches for Biomarker Panels in Cancer. Journal of Immunoassay and Immunochemistry 37:1, pages 1-15.
Read now
Read now
Juliet Richman, Juan Martin-Liberal, Stefan Diem & James Larkin. (2015) BRAF and MEK inhibition for the treatment of advanced BRAF mutant melanoma. Expert Opinion on Pharmacotherapy 16:9, pages 1285-1297.
Read now
Read now
Chongwen Xu, Xin Sun, Sida Qin, Huangzhen Wang, Zhiwei Zheng, Shaohua Xu, Gang Luo, Peng Liu, Jian Liu, Ning Du, Yunfeng Zhang, Dapeng Liu & Hong Ren. (2015) Let-7a regulates mammosphere formation capacity through Ras/NF-κB and Ras/MAPK/ERK pathway in breast cancer stem cells. Cell Cycle 14:11, pages 1686-1697.
Read now
Read now
Yong Feng, Jacson K Shen, Francis J Hornicek & Zhenfeng Duan. (2014) Genomic and epigenetic instability in chordoma: current insights. Advances in Genomics and Genetics 4, pages 67-78.
Read now
Read now
Mei Jing Piao, Ki Cheon Kim, Jian Zheng, Cheng Wen Yao, Ji Won Cha, Sun Jin Boo, Weon Jong Yoon, Hee Kyoung Kang, Eun Sook Yoo, Young Sang Koh, Mi Hee Ko, Nam Ho Lee & Jin Won Hyun. (2014) The ethyl acetate fraction of Sargassum muticum attenuates ultraviolet B radiation-induced apoptotic cell death via regulation of MAPK- and caspase-dependent signaling pathways in human HaCaT keratinocytes. Pharmaceutical Biology 52:9, pages 1110-1118.
Read now
Read now
Juan Martin-Liberal & James Larkin. (2014) New RAF kinase inhibitors in cancer therapy. Expert Opinion on Pharmacotherapy 15:9, pages 1235-1245.
Read now
Read now
Juan Martin-Liberal, Laura Lagares-Tena & James Larkin. (2014) Prospects for MEK inhibitors for treating cancer. Expert Opinion on Drug Safety 13:4, pages 483-495.
Read now
Read now
Elena Sacco, Michela Spinelli & Marco Vanoni. (2012) Approaches to Ras signaling modulation and treatment of Ras-dependent disorders: a patent review (2007 – present). Expert Opinion on Therapeutic Patents 22:11, pages 1263-1287.
Read now
Read now
Mercedes González & Hugo Cerecetto. (2012) Quinoxaline derivatives: a patent review (2006 – present). Expert Opinion on Therapeutic Patents 22:11, pages 1289-1302.
Read now
Read now
Articles from other publishers (589)
Patricia Kasowanjete, Sathish Sundar Dhilip Kumar & Nicolette N. Houreld. (2024) A review of photobiomodulation on PI3K/AKT/mTOR in wound healing. Journal of Photochemistry and Photobiology 19, pages 100215.
Crossref
Crossref
Lili Liu, Xiaoyi Gong, Xinyu Zhang, Dawei Zhang, Ying Tang, Jiantao Liu, Yajie Li & Disheng Pan. (2024) Resveratrol alleviates heat-stress-induced impairment of the jejunal mucosa through TLR4/MAPK signaling pathway in black-boned chicken. Poultry Science 103:1, pages 103242.
Crossref
Crossref
Ke Sun, Yize Sun, Yunna Jia, Xinran Duan, Zhenhua Ma, Xiqing Zhang, Lixia Wang, Yanbin Zhu, Yunhang Gao & Wangdui Basang. (2023) MicroRNA miR-212-5p Regulates the MEK/ERK Signaling Pathway by Targeting A-Raf proto-oncogene serine/threonine-protein kinase (ARAF) to Regulate Cowshed PM2.5-Induced NR8383 Apoptosis. Toxics 11:12, pages 981.
Crossref
Crossref
Saidul Islam Nayan, Md Habibur Rahman, Md. Mehedi Hasan, Sheikh Md. Razibul Hasan Raj, Mohammad Ali Abdullah Almoyad, Pietro Liò & Mohammad Ali Moni. (2023) Network based approach to identify interactions between Type 2 diabetes and cancer comorbidities. Life Sciences 335, pages 122244.
Crossref
Crossref
Tao Liu, Wan Xiang, Zhizhuang Chen, Gang Wang, Rui Cao, Fenfang Zhou, Zhe Meng, Yongwen Luo & Liang Chen. (2023) Hypoxia-induced PLOD2 promotes clear cell renal cell carcinoma progression via modulating EGFR-dependent AKT pathway activation. Cell Death & Disease 14:11.
Crossref
Crossref
Langlang Chen, Xin Fan, Lina YangLu Han, Ningbo Wang & Ka Bian. (2023) Research progress of glucocorticoid resistance in chronic rhinosinusitis with nasal polyps: A review. Medicine 102:46, pages e36024.
Crossref
Crossref
Yakinthi Batsi, Georgia Antonopoulou, Theano Fotopoulou, Kassandra Koumaki, Eftichia Kritsi, Constantinos Potamitis, Maria Goulielmaki, Salomi Skarmalioraki, Chara Papalouka, Eleni Poulou‐Sidiropoulou, Vivian Kosmidou, Stavroula Douna, Maria‐Sofia Vidali, Eleni‐Fani Gkotsi, Aristotelis Chatziioannou, Vassilis L. Souliotis, Vasiliki Pletsa, Olga Papadodima, Vassilis Zoumpourlis, Panagiotis Georgiadis, Maria Zervou, Alexander Pintzas & Ioannis D. Kostas. (2023)
Design and Synthesis of Novel 2‐Acetamido, 6‐Carboxamide Substituted Benzothiazoles as Potential BRAFV600E Inhibitors –
In vitro
Evaluation of their Antiproliferative Activity
. ChemMedChem 18:22.
Crossref
Crossref
Md. Al Amin, Talha Bin Emran, Jishan Khan, Mehrukh Zehravi, Indu Sharma, Anasuya Patil, Jeetendra Kumar Gupta, D. Jeslin, Karthickeyan Krishnan, Rajib Das, Firzan Nainu, Irfan Ahmad & Polrat Wilairatana. (2023) Research Progress of Indole Alkaloids: Targeting MAP Kinase Signaling Pathways in Cancer Treatment. Cancers 15:22, pages 5311.
Crossref
Crossref
Quanli Zhang, Limin Zheng, Yongkang Bai, Chi Su, Yuru Che, Jiawen Xu, Kemin Sun, Jie Ni, Lingli Huang, Ye Shen, Lili Jia, Lin Xu, Rong Yin, Ming Li & Jingwen Hu. (2023) ITPR1-AS1 promotes small cell lung cancer metastasis by facilitating P21 splicing and stabilizing DDX3X to activate the cRaf-MEK-ERK cascade. Cancer Letters 577, pages 216426.
Crossref
Crossref
Chang Xiao, Yue Sun, Jialong Fan, William Nguyen, Simin Chen, Ying Long, Wei Chen, Aiguo Zhu & Bin Liu. (2023) Engineering cannabidiol synergistic carbon monoxide nanocomplexes to enhance cancer therapy via excessive autophagy. Acta Pharmaceutica Sinica B 13:11, pages 4591-4606.
Crossref
Crossref
Pengyu Zhang, Wendi Liu & Yuan Wang. (2023) The mechanisms of tanshinone in the treatment of tumors. Frontiers in Pharmacology 14.
Crossref
Crossref
Humzah Postwala, Yesha Shah, Priyajeet S. Parekh & Mehul R. Chorawala. (2023) Unveiling the genetic and epigenetic landscape of colorectal cancer: new insights into pathogenic pathways. Medical Oncology 40:11.
Crossref
Crossref
Lenora Higginbotham, E. Kathleen Carter, Eric B. Dammer, Rafi U. Haque, Erik C.B. Johnson, Duc M. Duong, Luming Yin, Philip L. De Jager, David A. Bennett, Daniel Felsky, Earvin S. Tio, James J. Lah, Allan I. Levey & Nicholas T. Seyfried. (2023) Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment. Neurobiology of Disease 186, pages 106286.
Crossref
Crossref
Jinrui Wei, Yan Zhang, Haopeng Li, Fuquan Wang & Shanglong Yao. (2023) Toll-like receptor 4: A potential therapeutic target for multiple human diseases. Biomedicine & Pharmacotherapy 166, pages 115338.
Crossref
Crossref
Chowdhury Lutfun Nahar Metu, Sunita Kumari Sutihar, Md Sohel, Fatematuz Zohora, Akayed Hasan, Md. Thandu Miah, Tanu Rani Kar, Md. Arju Hossain & Md Habibur Rahman. (2023) Unraveling the signaling mechanism behind astrocytoma and possible therapeutics strategies: A comprehensive review. Cancer Reports 6:10.
Crossref
Crossref
Melissa Dang, Justin Yu, Jessica Galant‐Swafford & Sana D. Karam. (2023) The dichotomy of regulatory B cells in cancer versus allergic disease. Molecular Carcinogenesis.
Crossref
Crossref
Andreea Crintea, Anne-Marie Constantin, Alexandru C. Motofelea, Carmen-Bianca Crivii, Maria A. Velescu, Răzvan L. Coșeriu, Tamás Ilyés, Alexandra M. Crăciun & Ciprian N. Silaghi. (2023) Targeted EGFR Nanotherapy in Non-Small Cell Lung Cancer. Journal of Functional Biomaterials 14:9, pages 466.
Crossref
Crossref
Ankita Thakur, Neha Prasad, Kirti Raina, Rohit Sharma & Ashun Chaudhary. (2023) Role of Plant-Based Anticancer Compounds in Treatment of Breast Cancer. Current Pharmacology Reports 9:6, pages 468-488.
Crossref
Crossref
Vaia Florou, Andrew Elliott, Matthew H. Bailey, David Stone, Kajsa Affolter, Heloisa P. Soares, Chris Nevala-Plagemann, Courtney Scaife, Phillip Walker, W. Michael Korn, Emil Lou, Rachna T. Shroff, Peter J. Hosein & Ignacio Garrido-Laguna. (2023) Comparative Genomic Analysis of Pancreatic Acinar Cell Carcinoma (PACC) and Pancreatic Ductal Adenocarcinoma (PDAC) Unveils New Actionable Genomic Aberrations in PACC. Clinical Cancer Research 29:17, pages 3408-3417.
Crossref
Crossref
Man Zhang, Chengxu Zhu, Zeyu Luo, Junhao Liu, Muhammad Tahir Khan, Yawen Sun, Dong-Qing Wei & Yu-Juan Zhang. (2023) Exploring Key Proteins, Pathways and Oxygen Usage Bias of Proteins and Metabolites in Melanoma. Journal of Computational Biophysics and Chemistry 22:06, pages 673-686.
Crossref
Crossref
Ming Huang, Zhongbing Wu, Lei Jia, Yu Wang, Shuang Gao, Ying Liu, Yushuang Zhang & Jing Li. (2023) Bioinformatics and network pharmacology identify promotional effects and potential mechanisms of ethanol on esophageal squamous cell carcinoma and experimental validation. Toxicology and Applied Pharmacology 474, pages 116615.
Crossref
Crossref
Chandran S. Abhinand, Josephine Galipon, Masaru Mori, Poornima Ramesh, Thottethodi Subrahmanya Keshava Prasad, Rajesh Raju, Perumana R. Sudhakaran & Masaru Tomita. (2023) Temporal phosphoproteomic analysis of VEGF-A signaling in HUVECs: an insight into early signaling events associated with angiogenesis. Journal of Cell Communication and Signaling 17:3, pages 1067-1079.
Crossref
Crossref
Jiahao Li, Lei Xian, Zifeng Zhu, Yang Wang, Wenlei Zhang, Ruipeng Zheng, Wang Xue & Jiarui Li. (2023) Role of CELF2 in ferroptosis: Potential targets for cancer therapy (Review). International Journal of Molecular Medicine 52:4.
Crossref
Crossref
Xia Li, Joanna J Tibenda, Yi Nan, Shi-Cong Huang, Na Ning, Guo-Qing Chen, Yu-Hua Du, Ya-Ting Yang, Fan-Di Meng & Ling Yuan. (2023) MiR-204-3p overexpression inhibits gastric carcinoma cell proliferation by inhibiting the MAPK pathway and RIP1/MLK1 necroptosis pathway to promote apoptosis. World Journal of Gastroenterology 29:29, pages 4542-4556.
Crossref
Crossref
Samaneh Vaziri-Amjad, Massoud Moradi-Najmi & Amir Taherkhani. (2023) Natural Anthraquinones as Promising MAPK3 Inhibitors for Complementary Cancer Therapy. Journal of Chemistry 2023, pages 1-13.
Crossref
Crossref
Sandra Kannampuzha & Abilash Valsala Gopalakrishnan. (2023) Cancer chemoresistance and its mechanisms: Associated molecular factors and its regulatory role. Medical Oncology 40:9.
Crossref
Crossref
Abuyaseer Abusaliya, Se Hyo Jeong, Pritam Bhagwan Bhosale, Hun Hwan Kim, Min Yeong Park, Eunhye Kim, Chung Kil Won, Kwang Il Park, Jeong Doo Heo, Hyun Wook Kim, Meejung Ahn, Je Kyung Seong & Gon Sup Kim. (2023) Mechanistic Action of Cell Cycle Arrest and Intrinsic Apoptosis via Inhibiting Akt/mTOR and Activation of p38-MAPK Signaling Pathways in Hep3B Liver Cancer Cells by Prunetrin—A Flavonoid with Therapeutic Potential. Nutrients 15:15, pages 3407.
Crossref
Crossref
Ksenia Golub, Weiyu Bai, Zhimeng Zhang, Huilin Xiao, Rongyuan Sun, Junling Shen & Jianwei Sun. (2023) The mechanism and consequences of BRAF inhibitor resistance in melanoma. Genome Instability & Disease 4:5, pages 266-274.
Crossref
Crossref
Izabela Chmielewska, Paweł Krawczyk, Anna Grenda, Magdalena Wójcik-Superczyńska, Natalia Krzyżanowska, Michał Gil & Janusz Milanowski. (2023) Breaking the ‘Undruggable’ Barrier: Anti-PD-1/PD-L1 Immunotherapy for Non-Small Cell Lung Cancer Patients with KRAS Mutations—A Comprehensive Review and Description of Single Site Experience. Cancers 15:14, pages 3732.
Crossref
Crossref
Amjad Z. Alrosan, Ghaith B. Heilat, Zeinab Y. Al Subeh, Khaled Alrosan, Alaa F. Alrousan, Amro K. Abu-Safieh & Nuwar S. Alabdallat. (2023) The effects of statin therapy on brain tumors, particularly glioma: a review. Anti-Cancer Drugs.
Crossref
Crossref
Rui Sousa Martins, Tito Teles Jesus, Luís Cardoso, Paula Soares & João Vinagre. (2023) Personalized Medicine in Medullary Thyroid Carcinoma: A Broad Review of Emerging Treatments. Journal of Personalized Medicine 13:7, pages 1132.
Crossref
Crossref
Mateusz Kciuk, Manzar Alam, Nemat Ali, Summya Rashid, Pola Głowacka, Rajamanikandan Sundaraj, Ismail Celik, Esam Bashir Yahya, Amit Dubey, Enfale Zerroug & Renata Kontek. (2023) Epigallocatechin-3-Gallate Therapeutic Potential in Cancer: Mechanism of Action and Clinical Implications. Molecules 28:13, pages 5246.
Crossref
Crossref
Zachary A. Bordeaux, Justin Choi, Gabriella Braun, Cole Davis, Melika Marani, Kevin Lee, Christeen Samuel, Jackson Adams, Reed Windom, Anthony Pollizzi, Anusha Kambala, Hannah Cornman, Sriya V. Reddy, Weiying Lu, Olusola O. Oladipo, Martin P. Alphonse, Cameron E. West, Shawn G. Kwatra & Madan M. Kwatra. (2023) Topical GZ21T Inhibits the Growth of Actinic Keratoses in a UVB-Induced Model of Skin Carcinogenesis. JID Innovations 3:4, pages 100206.
Crossref
Crossref
Aleksandra Derwich, Monika Sykutera, Barbara Bromińska, Błażej Rubiś, Marek Ruchała & Nadia Sawicka-Gutaj. (2023) The Role of Activation of PI3K/AKT/mTOR and RAF/MEK/ERK Pathways in Aggressive Pituitary Adenomas—New Potential Therapeutic Approach—A Systematic Review. International Journal of Molecular Sciences 24:13, pages 10952.
Crossref
Crossref
Sara Salucci, Beatrice Aramini, Anna Bartoletti-Stella, Ilaria Versari, Giovanni Martinelli, William Blalock, Franco Stella & Irene Faenza. (2023) Phospholipase Family Enzymes in Lung Cancer: Looking for Novel Therapeutic Approaches. Cancers 15:12, pages 3245.
Crossref
Crossref
Zihan Chen, Yingying Dong, Qiuying Yan, Qin Li, Chengtao Yu, Yueyang Lai, Jiani Tan, Minmin Fan, Changliang Xu, Liu Li, Weixing Shen, Junfei Gu, Haibo Cheng & Dongdong Sun. (2023) Liquid chromatography-tandem mass spectrometry analysis of a ratio-optimized drug pair of Sophora flavescens Aiton and Coptis chinensis Franch and study on the mechanism of anti-colorectal cancer effect of two alkaloids thereof. Frontiers in Oncology 13.
Crossref
Crossref
Ting Liang, Yingxiang Yang, Jiayun Wang, Zhao Xie & Xin Chen. (2023) The Application of Pyrrolo[2, 3-d]pyrimidine Scaffold in Medicinal Chemistry
from 2017 to 2021. Mini-Reviews in Medicinal Chemistry 23:10, pages 1118-1136.
Crossref
Crossref
Alica M. Goldman. (2023) Oncogenic Pathways Provide Clue to the Etiology of Human Mesial Temporal Lobe Epilepsy. JAMA Neurology 80:6, pages 546.
Crossref
Crossref
Sida Zhao, Bin Li, Yiyuan Chen, Chuzhong Li & Yazhuo Zhang. (2023) Analysis of the Prognostic and Immunological Role of HSPB1 in Pituitary Adenoma: A Potential Target for Therapy. Medicina 59:5, pages 885.
Crossref
Crossref
Vikram Bhatia, Laya Esmati & Rajinder P. Bhullar. (2023) Regulation of Ras p21 and RalA GTPases activity by quinine in mammary epithelial cells. Molecular and Cellular Biochemistry.
Crossref
Crossref
Abhishek Chaurasiya, Chandrakant Sahu, Simranpreet K. Wahan & Pooja A. Chawla. (2023) Targeting cancer through recently developed purine clubbed heterocyclic scaffolds: An overview. Journal of Molecular Structure 1280, pages 134967.
Crossref
Crossref
Richa Singh, Esita Chattopadhyay, Anindita Ray, Roshni Roy, Nidhan K. Biswas, Sandip Ghose & Bidyut Roy. (2023) Integrative study of whole exome variation and expression in gingivo-buccal oral squamous cell carcinoma revealed alteration in TLR-activated MAP-Kinase signalling. Human Gene 36, pages 201183.
Crossref
Crossref
Susanne Edelmann, Ariane Wiegand, Thomas Hentrich, Sarah Pasche, Julia Maria Schulze-Hentrich, Matthias H. J. Munk, Andreas J. Fallgatter, Benjamin Kreifelts & Vanessa Nieratschker. (2023) Blood transcriptome analysis suggests an indirect molecular association of early life adversities and adult social anxiety disorder by immune-related signal transduction. Frontiers in Psychiatry 14.
Crossref
Crossref
Leon Katzengruber, Pascal Sander & Stefan Laufer. (2023) MKK4 Inhibitors—Recent Development Status and Therapeutic Potential. International Journal of Molecular Sciences 24:8, pages 7495.
Crossref
Crossref
Amna Amin Sethi & Nisar Ahmed Shar. (2023) Identification of Liver Cancer Driver Mutations from COSMIC Data. International Journal of Cancer Management 16:1.
Crossref
Crossref
Shiqing Sun, Kai Zhang, Yuliang Wang, Zijun Zhou, Lihong Wang, Hong Zhao & Yu Zhang. (2023) Pharmacodynamic structure of deer antler base protein and its mammary gland hyperplasia inhibition mechanism by mediating Raf-1/MEK/ERK signaling pathway activation. Food & Function 14:7, pages 3319-3331.
Crossref
Crossref
Victor de Haidar e Bertozzo, Sueli Matilde da Silva Costa, Mirta Tomie Ito, Pedro Rodrigues Sousa da Cruz, Bruno Batista Souza, Vinicius Mandolesi Rios, Marina Gonçalves Monteiro Viturino, Júlia Nicoliello Pereira de Castro, Thiago Adalton Rosa Rodrigues, Carolina Lanaro, Dulcinéia Martins de Albuquerque, Roberta Casagrande Saez, Sara Teresinha Olalla Saad, Margareth Castro Ozelo, Fernando Ferreira Costa & Mônica Barbosa de Melo. (2023) Comparative transcriptome analysis of endothelial progenitor cells of HbSS patients with and without proliferative retinopathy. Experimental Biology and Medicine 248:8, pages 677-684.
Crossref
Crossref
Fan Bao, Su An, Yang Yang & Tian-Rui Xu. (2023) SODD Promotes Lung Cancer Tumorigenesis by Activating the PDK1/AKT and RAF/MEK/ERK Signaling. Genes 14:4, pages 829.
Crossref
Crossref
Julie A Tomolonis, Xin Xu, Kshiti H Dholakia, Chunchao Zhang, Linjie Guo, Amy N Courtney, Siyue Wang, Julien Balzeau, Gabriel A Barragán, Gengwen Tian, Erica J Di Pierro & Leonid S Metelitsa. (2023) Interaction between tumor cell TNFR2 and monocyte membrane-bound TNF-α triggers tumorigenic inflammation in neuroblastoma. Journal for ImmunoTherapy of Cancer 11:3, pages e005478.
Crossref
Crossref
Hui-yu Li, Wei-liang Qi, Yu-xiang Wang & Ling-hua Meng. (2023) Covalent inhibitor targets KRasG12C: A new paradigm for drugging the undruggable and challenges ahead. Genes & Diseases 10:2, pages 403-414.
Crossref
Crossref
Peng Zhang, Liang Chen, Fenfang Zhou, Zhiwen He, Gang Wang & Yongwen Luo. (2023) NRP1 promotes prostate cancer progression via modulating EGFR-dependent AKT pathway activation. Cell Death & Disease 14:2.
Crossref
Crossref
Asmaa Samy, Mehmet Kemal Ozdemir & Reda Alhajj. (2023) Studying the connection between SF3B1 and four types of cancer by analyzing networks constructed based on published research. Scientific Reports 13:1.
Crossref
Crossref
Lingli Hu, Lulu Li, Chen Yan, Yuxue Cao, Xiaohong Duan & Jing Sun. (2023) Baicalin Inhibits Airway Smooth Muscle Cells Proliferation through the RAS Signaling Pathway in Murine Asthmatic Airway Remodeling Model. Oxidative Medicine and Cellular Longevity 2023, pages 1-12.
Crossref
Crossref
Hongqiang Yao, Siriguleng Yu, Yuchen Luo, Ming Wang, Xiuying Wang, Siriguleng Xu, Yufei Chen & Zhifeng Xie. (2023) Effects of plasma-derived exosomes from the normal and thin Bactrian camels on hepatocellular carcinoma and their differences at transcriptome and proteomics levels. Frontiers in Oncology 13.
Crossref
Crossref
Huanping Zhang, Yanfen Wang, Xiaoxue Chen, Aizhi Zhang, Lijun Hou, Jingyi Hong, Jiangqi Liu, Zhiqiang Liu & Pingchang Yang. (2023) Targeting epithelial cell-derived TWIST1 alleviates allergic asthma. Cellular Signalling 102, pages 110552.
Crossref
Crossref
Runqing Wang, Jin Xu, Yuning Tang, Yongxiang Wang, Jing Zhao, Liqiong Ding, Yu Peng & Zheng Zhang. (2023) Transcriptome-wide analysis reveals the coregulation of RNA-binding proteins and alternative splicing genes in the development of atherosclerosis. Scientific Reports 13:1.
Crossref
Crossref
Bronwyn Lok, Dinesh Babu, Yasser Tabana, Saad Sabbar Dahham, Mowaffaq Adam Ahmed Adam, Khaled Barakat & Doblin Sandai. (2023) The Anticancer Potential of Psidium guajava (Guava) Extracts. Life 13:2, pages 346.
Crossref
Crossref
Michael A. Fawzy, Rania H. Abu-baih, Gamal El-Din A. Abuo-Rahma, Islam M. Abdel-Rahman, Azza A. K. El-Sheikh & Maiiada H. Nazmy. (2023) In Vitro Anticancer Activity of Novel Ciprofloxacin Mannich Base in Lung Adenocarcinoma and High-Grade Serous Ovarian Cancer Cell Lines via Attenuating MAPK Signaling Pathway. Molecules 28:3, pages 1137.
Crossref
Crossref
Xiao-Li Wei, Yang Zhang, Hong-Yun Zhao, Wen-Feng Fang, Hui-Yan Luo, Miao-Zhen Qiu, Ming-Ming He, Ben-Yan Zou, Jie Xie, Chun-Lei Jin, Xian-Feng Zhou, Feng Wang, Feng-Hua Wang, Yu-Hong Li, Zhi-Qiang Wang & Rui-Hua Xu. (2023) Safety and Clinical Activity of SHR7390 Monotherapy or Combined With Camrelizumab for Advanced Solid Tumor: Results From Two Phase I Trials. The Oncologist 28:1, pages e36-e44.
Crossref
Crossref
Yawen Yuan, Zhihong Li, Ke Wang, Shunguo Zhang, Qingfeng He, Lucy Liu, Zhijia Tang, Xiao Zhu, Ying Chen, Weimin Cai, Chao Peng & Xiaoqiang Xiang. (2023) Pharmacokinetics of Novel Furoxan/Coumarin Hybrids in Rats Using LC-MS/MS Method and Physiologically Based Pharmacokinetic Model. Molecules 28:2, pages 837.
Crossref
Crossref
Qi Zhang, Yifeng Zheng, Jiajia Liu, Xiaoxiao Tang, Yuan Wang, Xianzheng Li, Huibin Li, Xiaoying Zhou, Shiru Tang, Yitao Tang, Xiaoyan Wang, Han He & Tingting Li. (2023) CircIFNGR2 enhances proliferation and migration of CRC and induces cetuximab resistance by indirectly targeting KRAS via sponging to MiR-30b. Cell Death & Disease 14:1.
Crossref
Crossref
Leihao Hu, Canfeng He, Aier Mo, Xingkai Zhan, Caizhi Yang, Wei Guo, Lingling Sun, Weiwei Su & Lizhu Lin. (2023) A Mechanism Exploration for the Yi-Fei-San-Jie Formula against Non-Small-Cell Lung Cancer Based on UPLC-MS/MS, Network Pharmacology, and In Silico Verification. Evidence-Based Complementary and Alternative Medicine 2023, pages 1-16.
Crossref
Crossref
Y. Lan, Y. Liang, X. Xiao, Y. Shi, M. Zhu, C. Meng, S. Yang, M. T. Khan & Y. J. Zhang. (2023) Stoichioproteomics study of differentially expressed proteins and pathways in head and neck cancer. Brazilian Journal of Biology 83.
Crossref
Crossref
Fahai Chen, Yaping Wang, Xinling Zhang & Jianmin Fang. (2023) Five hub genes contributing to the oncogenesis and trastuzumab-resistance in gastric cancer. Gene 851, pages 146942.
Crossref
Crossref
Neetu Kumari, Mettle Brahma & Mulaka Maruthi. 2023. Treatment Landscape of Targeted Therapies in Oncology. Treatment Landscape of Targeted Therapies in Oncology
95
134
.
Caio Bezerra Machado, Flávia Melo Cunha de Pinho Pessoa, Raquel Carvalho Montenegro, Maria Elisabete Amaral de Moraes & Caroline Aquino Moreira-Nunes. 2023. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.
Michele Bibas. 2023. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.
Nour Y.S. Yassin, Mohamed Y. Zaky & Osama M. Ahmed. 2023. Phospholipases in Physiology and Pathology. Phospholipases in Physiology and Pathology
239
253
.
Krishna Mohan Poluri, Khushboo Gulati, Deepak Kumar Tripathi & Nupur NagarKrishna Mohan Poluri, Khushboo Gulati, Deepak Kumar Tripathi & Nupur Nagar. 2023. Protein-Protein Interactions. Protein-Protein Interactions
43
100
.
Manjusha Dixit, Vinay J & Soham Choudhury. 2023. Gallbladder Cancer. Gallbladder Cancer
291
316
.
Nilam Bhasker & Faraz Ahmad. 2023. Gallbladder Cancer. Gallbladder Cancer
269
290
.
Monica R. P. Rao, Isha Ghadge, Saurav Kulkarni & Ashwini R. Madgulkar. 2023. Plant Specialized Metabolites. Plant Specialized Metabolites
1
31
.
Nangwon Yee, Hyeonjin Kim, Eungyung Kim, Yong Ho Cha, Lei Ma, Na Eun Cho, Dongwook Kim, Chae Yeon Kim, Sung-Hyun Kim, Zaeyoung Ryoo, Junkoo Yi & Myoung Ok Kim. (2022) Effects of Sangju Honey on Oral Squamous Carcinoma Cells. Journal of Cancer Prevention 27:4, pages 239-246.
Crossref
Crossref
Alfonso López de Sá, Alicia de Luna, Mónica Antoñanzas, Vanesa García-Barberán, Fernando Moreno-Anton & Jose A. García-Sáenz. (2022) Case report: Clinical success targeting BRAF-mutated, hormone receptor positive, HER2- negative advanced breast cancer patient with BRAF-inhibitor plus MEK- inhibitor. Frontiers in Oncology 12.
Crossref
Crossref
Eiru Kim, Lance C. Novak, Chenchu Lin, Medina Colic, Lori L. Bertolet, Veronica Gheorghe, Christopher A. Bristow & Traver Hart. (2022) Dynamic rewiring of biological activity across genotype and lineage revealed by context-dependent functional interactions. Genome Biology 23:1.
Crossref
Crossref
Weiguo Xu, Junyu Zheng, Xiao Wang, Bin Zhou, Huanqiu Chen, Gang Li & Feng Yan. (2022) tRF-Val-CAC-016 modulates the transduction of CACNA1d-mediated MAPK signaling pathways to suppress the proliferation of gastric carcinoma. Cell Communication and Signaling 20:1.
Crossref
Crossref
Nunzio Del Gaudio, Antonella Di Costanzo, Ning Qing Liu, Lidio Conte, Carmela Dell’Aversana, Guglielmo Bove, Rosaria Benedetti, Liliana Montella, Fortunato Ciardiello, Vincenzo Carafa, Concetta Ambrosino, Valeria Tucci, Mariarosaria Conte, Joost H. A. Martens, Hendrik G. Stunnenberg, Angela Nebbioso & Lucia Altucci. (2022) CBX2 shapes chromatin accessibility promoting AML via p38 MAPK signaling pathway. Molecular Cancer 21:1.
Crossref
Crossref
Nan Hao, Daming Yang, Tianpei Liu, Shucheng Liu, Xinsheng Lu & Libo Chen. (2022) Laminin-integrin a6b4 interaction activates notch signaling to facilitate bladder cancer development. BMC Cancer 22:1.
Crossref
Crossref
Dongliao Fu, Zhigang Hu, Xinyang Xu, Xiaoyan Dai & Ziyi Liu. (2022) Key signal transduction pathways and crosstalk in cancer: Biological and therapeutic opportunities. Translational Oncology 26, pages 101510.
Crossref
Crossref
Jinying Gu, Qiuyu Wu, Qiuyue Zhang, Qidong You & Lei Wang. (2022) A decade of approved first-in-class small molecule orphan drugs: Achievements, challenges and perspectives. European Journal of Medicinal Chemistry 243, pages 114742.
Crossref
Crossref
Liu-Fang Ye, Zi-Yao Huang, Xiao-Xi Chen, Zhi-Gang Chen, Si-Xian Wu, Chao Ren, Ming-Tao Hu, Hua Bao, Ying Jin, Feng Wang, Feng-Hua Wang, Zi-Ming Du, Xue Wu, Huai-Qiang Ju, Yang Shao, Yu-Hong Li, Rui-Hua Xu & De-Shen Wang. (2022) Monitoring tumour resistance to the BRAF inhibitor combination regimen in colorectal cancer patients via circulating tumour DNA. Drug Resistance Updates 65, pages 100883.
Crossref
Crossref
Apurva, Real Sumayya Abdul Sattar, Asgar Ali, Nimisha, Abhay Kumar Sharma, Arun Kumar, Seneha Santoshi & Sundeep Singh Saluja. (2022) Molecular pathways in periampullary cancer: An overview. Cellular Signalling 100, pages 110461.
Crossref
Crossref
Minsoo Kim & Eunjung Kim. (2022) Mathematical model of the cell signaling pathway based on the extended Boolean network model with a stochastic process. BMC Bioinformatics 23:1.
Crossref
Crossref
Yu Zhang, Dimitrios Vagiannis, Youssif Budagaga, Ziba Sabet, Ivo Hanke, Tomáš Rozkoš & Jakub Hofman. (2022) Encorafenib Acts as a Dual-Activity Chemosensitizer through Its Inhibitory Effect on ABCC1 Transporter In Vitro and Ex Vivo. Pharmaceutics 14:12, pages 2595.
Crossref
Crossref
Dailin Gan, Guosheng Yin & Yan Dora Zhang. (2022) The GR2D2 estimator for the precision matrices. Briefings in Bioinformatics 23:6.
Crossref
Crossref
Aya M. Hussein, Nadia M. El-Beih, Menha Swellam & Enas A. El-Hussieny. (2022) Pomegranate juice and punicalagin-mediated chemoprevention of hepatocellular carcinogenesis via regulating miR-21 and NF-κB-p65 in a rat model. Cancer Cell International 22:1.
Crossref
Crossref
Oren Yakovian, Julia Sajman, Michal Alon, Rand Arafeh, Yardena Samuels & Eilon Sherman. (2022) NRas activity is regulated by dynamic interactions with nanoscale signaling clusters at the plasma membrane. iScience 25:11, pages 105282.
Crossref
Crossref
Thibault Houles, Geneviève Lavoie, Sami Nourreddine, Winnie Cheung, Éric Vaillancourt-Jean, Célia M. Guérin, Mathieu Bouttier, Benoit Grondin, Sichun Lin, Marc K. Saba-El-Leil, Stephane Angers, Sylvain Meloche & Philippe P. Roux. (2022) CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma. Nature Communications 13:1.
Crossref
Crossref
Tienthanh Nguyen, Ruiyin Guo, Jinwei Chai, Jiena Wu, Junfang Liu, Xin Chen, Mohamed A. Abdel-Rahman, Hu Xia & Xueqing Xu. (2022) Smp24, a Scorpion-Venom Peptide, Exhibits Potent Antitumor Effects against Hepatoma HepG2 Cells via Multi-Mechanisms In Vivo and In Vitro. Toxins 14:10, pages 717.
Crossref
Crossref
Muthu Kumar Thirunavukkarasu, Shanthi Veerappapillai & Ramanathan Karuppasamy. (2022) Computational biophysics approach towards the discovery of multi-kinase blockers for the management of MAPK pathway dysregulation. Molecular Diversity.
Crossref
Crossref
Yufei Long, Tuotuo Chong, Xiaoming Lyu, Lujia Chen, Xiaomin Luo, Oluwasijibomi Damola Faleti, Simin Deng, Fei Wang, Mingliang He, Zhipeng Qian, Hongli Zhao, Wenyan Zhou, Xia Guo, Ceshi Chen & Xin Li. (2022) FOXD1-dependent RalA-ANXA2-Src complex promotes CTC formation in breast cancer. Journal of Experimental & Clinical Cancer Research 41:1.
Crossref
Crossref
A. Kahsay, E. Rodriguez-Marquez, A. López-Pérez, A. Hörnblad & J. von Hofsten. (2022) Pax3 loss of function delays tumour progression in kRAS-induced zebrafish rhabdomyosarcoma models. Scientific Reports 12:1.
Crossref
Crossref
Rahim Ullah, Qing Yin, Aidan H. Snell & Lixin Wan. (2022) RAF-MEK-ERK pathway in cancer evolution and treatment. Seminars in Cancer Biology 85, pages 123-154.
Crossref
Crossref
Xin Wen, Si Chen, Xueting Chen, Hui Qiu, Wei Wang, Nie Zhang, Wanming Liu, Tingting Wang, Xin Ding & Longzhen Zhang. (2022) ITGB5 promotes innate radiation resistance in pancreatic adenocarcinoma by promoting DNA damage repair and the MEK/ERK signaling pathway. Frontiers in Oncology 12.
Crossref
Crossref
Aranka Brockmueller, Anna-Lena Mueller, Ajaikumar B. Kunnumakkara, Bharat B. Aggarwal & Mehdi Shakibaei. (2022) Multifunctionality of Calebin A in inflammation, chronic diseases and cancer. Frontiers in Oncology 12.
Crossref
Crossref
Feng Zhang, Kumar Ganesan, Qingqing Liu & Jianping Chen. (2022) A Review of the Pharmacological Potential of Spatholobus suberectus Dunn on Cancer. Cells 11:18, pages 2885.
Crossref
Crossref
Rui Qin, Feng-Ming You, Qian Zhao, Xin Xie, Cheng Peng, Gu Zhan & Bo Han. (2022) Naturally derived indole alkaloids targeting regulated cell death (RCD) for cancer therapy: from molecular mechanisms to potential therapeutic targets. Journal of Hematology & Oncology 15:1.
Crossref
Crossref
Guan-Nan Li, Xue-Jiao Zhao, Zhen Wang, Meng-Shi Luo, Shen-Nan Shi, Dan-Mei Yan, Hua-Yi Li, Jia-Hao Liu, Yang Yang, Jia-Hong Tan, Ze-Yu Zhang, Ru-Qi Chen, Hui-Ling Lai, Xiao-Yuan Huang, Jian-Feng Zhou, Ding Ma, Yong Fang & Qing-Lei Gao. (2022) Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation. Signal Transduction and Targeted Therapy 7:1.
Crossref
Crossref
Ryo Kurokawa, Mariko Kurokawa, Akira Baba, Yoshiaki Ota, Emile PinarbasiSandra Camelo-Piragua, Aristides A. Capizzano, Eric LiaoAshok Srinivasan & Toshio Moritani. (2022) Major Changes in 2021 World Health Organization Classification of Central Nervous System Tumors. RadioGraphics 42:5, pages 1474-1493.
Crossref
Crossref
Maryam Kohansal, Ali Ghanbarisad, Reza Tabrizi, Abdolreza Daraei, Mojtaba Kashfi, Hailin Tang, Cailu Song & Yongming Chen. (2022)
tRNA‐
derived fragments in gastric cancer: Biomarkers and functions
. Journal of Cellular and Molecular Medicine 26:18, pages 4768-4780.
Crossref
Crossref
Dario Talloa, Silvia Triarico, Pierpaolo Agresti, Stefano Mastrangelo, Giorgio Attinà, Alberto Romano, Palma Maurizi & Antonio Ruggiero. (2022) BRAF and MEK Targeted Therapies in Pediatric Central Nervous System Tumors. Cancers 14:17, pages 4264.
Crossref
Crossref
Ruiyin Guo, Xuewen Chen, Tienthanh Nguyen, Jinwei Chai, Yahua Gao, Jiena Wu, Jinqiao Li, Mohamed A. Abdel-Rahman, Xin Chen & Xueqing Xu. (2022) The Strong Anti-Tumor Effect of Smp24 in Lung Adenocarcinoma A549 Cells Depends on Its Induction of Mitochondrial Dysfunctions and ROS Accumulation. Toxins 14:9, pages 590.
Crossref
Crossref
Khadijeh Barzaman, Rana Vafaei, Mitra Samadi, Mohammad Hossein Kazemi, Aysooda Hosseinzadeh, Parnaz Merikhian, Shima Moradi-Kalbolandi, Mohammad Reza Eisavand, Houra Dinvari & Leila Farahmand. (2022) Anti-cancer therapeutic strategies based on HGF/MET, EpCAM, and tumor-stromal cross talk. Cancer Cell International 22:1.
Crossref
Crossref
Yesen Zhang, Huasheng Fan, Chun Zou, Feng Wei, Jiwei Sun, Yuchun Shang, Liechun Chen, Xiangyu Wang & Beiquan Hu. (2022) Screening seven hub genes associated with prognosis and immune infiltration in glioblastoma. Frontiers in Genetics 13.
Crossref
Crossref
Hong-Beom Park, Sohyun Hwang & Kwang-Hyun Baek. (2022) USP7 regulates the ERK1/2 signaling pathway through deubiquitinating Raf-1 in lung adenocarcinoma. Cell Death & Disease 13:8.
Crossref
Crossref
Guang-Xi Yu, Ying Hu, Wei-Xin Zhang, Xin-Yi Tian, Sai-Yang Zhang, Yan Zhang, Shuo Yuan & Jian Song. (2022) Design, Synthesis and Biological Evaluation of [1,2,4]Triazolo[1,5-a]pyrimidine Indole Derivatives against Gastric Cancer Cells MGC-803 via the Suppression of ERK Signaling Pathway. Molecules 27:15, pages 4996.
Crossref
Crossref
Sheng Pan & Ru Chen. (2022) Pathological implication of protein post-translational modifications in cancer. Molecular Aspects of Medicine 86, pages 101097.
Crossref
Crossref
Yue Li, Li-Hong Chang, Wei-Qiang Huang, Hong-Wei Bao, Xia Li, Xiao-Hong Chen, Hao-Tian Wu, Zhou-Zhou Yao, Zi-Zhen Huang, Samuel E. Weinberg, De-Yu Fang, Ya-Na Zhang & Ge-Hua Zhang. (2022) IL-17A mediates pyroptosis via the ERK pathway and contributes to steroid resistance in CRSwNP. Journal of Allergy and Clinical Immunology 150:2, pages 337-351.
Crossref
Crossref
Chengzhi Huang, Hui Yi, Yue Zhou, Qing Zhang & Xueqing Yao. (2022) Pan-Cancer Analysis Reveals SH3TC2 as an Oncogene for Colorectal Cancer and Promotes Tumorigenesis via the MAPK Pathway. Cancers 14:15, pages 3735.
Crossref
Crossref
Naoshad Muhammad, Darksha Usmani, Mohammad Tarique, Huma Naz, Mohammad Ashraf, Ramesh Raliya, Shams Tabrez, Torki A. Zughaibi, Ahdab Alsaieedi, Israa J. Hakeem & Mohd Suhail. (2022) The Role of Natural Products and Their Multitargeted Approach to Treat Solid Cancer. Cells 11:14, pages 2209.
Crossref
Crossref
Olive S. Eckstein, Carl E. Allen, P. Mickey Williams, Sinchita Roy-Chowdhuri, David R. Patton, Brent Coffey, Joel M. Reid, Jin Piao, Lauren Saguilig, Todd A. Alonzo, Stacey L. Berg, Nilsa C. Ramirez, Alok Jaju, Joyce Mhlanga, Elizabeth Fox, Douglas S. Hawkins, Margaret M. Mooney, Naoko Takebe, James V. Tricoli, Katherine A. Janeway, Nita L. Seibel & D. Williams Parsons. (2022) Phase II Study of Selumetinib in Children and Young Adults With Tumors Harboring Activating Mitogen-Activated Protein Kinase Pathway Genetic Alterations: Arm E of the NCI-COG Pediatric MATCH Trial. Journal of Clinical Oncology 40:20, pages 2235-2245.
Crossref
Crossref
Xuhui Tong, Rong Tang, Jin Xu, Wei Wang, Yingjun Zhao, Xianjun Yu & Si Shi. (2022) Liquid–liquid phase separation in tumor biology. Signal Transduction and Targeted Therapy 7:1.
Crossref
Crossref
Emmanuel M. Kiyonga, Linda N. Kekani, Tinotenda V. Chidziwa, Kudzai D. Kahwenga, Elmien Bronkhorst, Marnus Milne, Madan S. Poka, Shoeshoe Mokhele, Patrick H. Demana & Bwalya A. Witika. (2022) Nano- and Crystal Engineering Approaches in the Development of Therapeutic Agents for Neoplastic Diseases. Crystals 12:7, pages 926.
Crossref
Crossref
Qianmiao Wu, Huaijun Tu & Jian Li. (2022) Multifaceted Roles of Chemokine C-X-C Motif Ligand 7 in Inflammatory Diseases and Cancer. Frontiers in Pharmacology 13.
Crossref
Crossref
Yongqiang Wang, Hewei Zhang, Zusen Ye, Qiang Ye, Xuezhi Yang, Wei Mao, Ruoting Xu & Yanlei Zhang. (2022) Maslinic Acid Inhibits the Growth of Malignant Gliomas by Inducing Apoptosis via MAPK Signaling. Journal of Oncology 2022, pages 1-11.
Crossref
Crossref
Rossella Loria, Patrizia Vici, Francesca Sofia Di Lisa, Silvia Soddu, Marcello Maugeri-Saccà & Giulia Bon. (2022) Cross-Resistance Among Sequential Cancer Therapeutics: An Emerging Issue. Frontiers in Oncology 12.
Crossref
Crossref
Qiao Yang, Xiaoyi Zhang, Huini Qin, Feijun Luo & Jiali Ren. (2022) Phenolic Acid Profiling of Lactarius hatsudake Extracts, Anti-Cancer Function and Its Molecular Mechanisms. Foods 11:13, pages 1839.
Crossref
Crossref
Eileena F. Giurini, Mary Beth Madonna, Andrew Zloza & Kajal H. Gupta. (2022) Microbial-Derived Toll-like Receptor Agonism in Cancer Treatment and Progression. Cancers 14:12, pages 2923.
Crossref
Crossref
Danian Dai, Qiang Li, Pengfei Zhou, Jianjiang Huang, Hongkai Zhuang, Hongmei Wu & Bo Chen. (2022) Analysis of Omics Data Reveals Nucleotide Excision Repair-Related Genes Signature in Highly-Grade Serous Ovarian Cancer to Predict Prognosis. Frontiers in Cell and Developmental Biology 10.
Crossref
Crossref
Ruth Nussinov, Chung-Jung Tsai & Hyunbum Jang. (2022) Neurodevelopmental disorders, immunity, and cancer are connected. iScience 25:6, pages 104492.
Crossref
Crossref
Zhiqing Xu & Ming Chu. (2022) Advances in Immunosuppressive Agents Based on Signal Pathway. Frontiers in Pharmacology 13.
Crossref
Crossref
Hye-Jung Nam, Yeon-Ju Kim, Jae-Hyeok Kang & Su-Jae Lee. (2022) GPR110 promotes progression and metastasis of triple-negative breast cancer. Cell Death Discovery 8:1.
Crossref
Crossref
Alan R. Cohen. (2022) Brain Tumors in Children. New England Journal of Medicine 386:20, pages 1922-1931.
Crossref
Crossref
Ryota Tamura & Masahiro Toda. (2022) A Critical Overview of Targeted Therapies for Vestibular Schwannoma. International Journal of Molecular Sciences 23:10, pages 5462.
Crossref
Crossref
Ritsuko Harigai, Ryo Sato, Chikako Hirose, Toshiki Takenouchi, Kenjiro Kosaki, Takanori Hirose, Hideyuki Saya & Yoshimi Arima. (2022) Mutation of PTPN11 (Encoding SHP-2) Promotes MEK Activation and Malignant Progression in Neurofibromin-Deficient Cells in a Manner Sensitive to BRAP Mutation. Cancers 14:10, pages 2377.
Crossref
Crossref
Weijia Zhang, Shuyi Sang, Chang Peng, George Q. Li, Ling Ou, Zhong Feng, Yuanjing Zou, Yuemei Yuan & Meicun Yao. (2022) Network Pharmacology and Transcriptomic Sequencing Analyses Reveal the Molecular Mechanism of Sanguisorba officinalis Against Colorectal Cancer. Frontiers in Oncology 12.
Crossref
Crossref
Linyan Xu, Yuanyuan Qin, Mengdi Liu, Jun Jiao, Dongyun Tu, Meng Zhang, Dongmei Yan, Xuguang Song, Cai Sun, Feng Zhu, Xiangmin Wang, Wei Sang & Kailin Xu. (2022) The Acetyltransferase KAT5 Inhibitor NU 9056 Promotes Apoptosis and Inhibits JAK2/STAT3 Pathway in Extranodal NK/T Cell Lymphoma. Anti-Cancer Agents in Medicinal Chemistry 22:8, pages 1530-1540.
Crossref
Crossref
Cornelia Braicu, Oana Zanoaga, Alina-Andreea Zimta, Adrian Bogdan Tigu, Kaitlyn L. Kilpatrick, Anupam Bishayee, Seyed Mohammad Nabavi & Ioana Berindan-Neagoe. (2022) Natural compounds modulate the crosstalk between apoptosis- and autophagy-regulated signaling pathways: Controlling the uncontrolled expansion of tumor cells. Seminars in Cancer Biology 80, pages 218-236.
Crossref
Crossref
Bruce E. Johnson, Christina S. Baik, Julien Mazieres, Harry J.M. Groen, Barbara Melosky, Jürgen Wolf, Fatemeh Asad Zadeh Vosta Kolaei, Wen-Hsing Wu, Stefanie Knoll, Meryem Ktiouet Dawson, Adam Johns & David Planchard. (2022) Clinical Outcomes With Dabrafenib Plus Trametinib in a Clinical Trial Versus Real-World Standard of Care in Patients With BRAF-Mutated Advanced NSCLC. JTO Clinical and Research Reports 3:5, pages 100324.
Crossref
Crossref
Fanglin Niu, Yi Yu, Zhuozhuo Li, Yuanyuan Ren, Zi Li, Qiang Ye, Ping Liu, Chenshuang Ji, Lu Qian & Yuyan Xiong. (2022) Arginase: An emerging and promising therapeutic target for cancer treatment. Biomedicine & Pharmacotherapy 149, pages 112840.
Crossref
Crossref
Huiping Liu, Huijuan Wang, Aijun Dong, Xiaoshuang Huo, Huaxiang Wang, Junchi Wang & Jianyong Si. (2022) The Inhibition of Gastric Cancer Cells’ Progression by 23,24-Dihydrocucurbitacin E through Disruption of the Ras/Raf/ERK/MMP9 Signaling Pathway. Molecules 27:9, pages 2697.
Crossref
Crossref
Xue Tang, Fen Chen, Li-Chun Xie, Si-Xi Liu & Hui-Rong Mai. (2022) Targeting metabolism: A potential strategy for hematological cancer therapy. World Journal of Clinical Cases 10:10, pages 2990-3004.
Crossref
Crossref
Lili Fu, Zhongming Wu, Yanjun Chu, Wenbin Chen, Ling Gao, Shumin Mu & Jiajun Zhao. (2022) Explore the Mechanism of Astragalus mongholicus Bunge against Nonalcoholic Fatty Liver Disease Based on Network Pharmacology and Experimental Verification. Gastroenterology Research and Practice 2022, pages 1-17.
Crossref
Crossref
Zihan Cui, Dapeng Li, Jun Zhao & Kai Chen. (2022) Falnidamol and cisplatin combinational treatment inhibits non-small cell lung cancer (NSCLC) by targeting DUSP26-mediated signal pathways. Free Radical Biology and Medicine 183, pages 106-124.
Crossref
Crossref
Xelha Araujo-Padilla, Eva Ramón-Gallegos, Francisco Díaz-Cedillo & Rafael Silva-Torres. (2022) Astragalin identification in graviola pericarp indicates a possible participation in the anticancer activity of pericarp crude extracts: In vitro and in silico approaches. Arabian Journal of Chemistry 15:4, pages 103720.
Crossref
Crossref
Simon Gray, Angela Lamarca, Julien Edeline, Heinz-Josef Klümpen, Richard A. Hubner, Mairéad G. McNamara & Juan W. Valle. (2022) Targeted Therapies for Perihilar Cholangiocarcinoma. Cancers 14:7, pages 1789.
Crossref
Crossref
Jue Hou, Zongsheng He, Tian Liu, Dongfeng Chen, Bin Wang, Qinglian Wen & Xi Zheng. (2022) Evolution of Molecular Targeted Cancer Therapy: Mechanisms of Drug Resistance and Novel Opportunities Identified by CRISPR-Cas9 Screening. Frontiers in Oncology 12.
Crossref
Crossref
Montserrat Lara-Velazquez, Yusuf Mehkri, Eric Panther, Jairo Hernandez, Dinesh Rao, Peter Fiester, Raafat Makary, Michael Rutenberg, Daryoush Tavanaiepour & Gazanfar Rahmathulla. (2022) Current Advances in the Management of Adult Craniopharyngiomas. Current Oncology 29:3, pages 1645-1671.
Crossref
Crossref
Xianghan Chen, Weiqi Cai, Ji Liu, Lanqun Mao & Ming Wang. (2022) Integration of Palladium Nanoparticles with Surface Engineered Metal–Organic Frameworks for Cell-Selective Bioorthogonal Catalysis and Protein Activity Regulation. ACS Applied Materials & Interfaces 14:8, pages 10117-10124.
Crossref
Crossref
Xiang Guo, Yi Fang, Congfang Guo, Qiong Jia, Zhiduan Chi, Jiaming Li, Rongfen Qin, Jingjing Tian & Ruiwen Fan. (2022) Qa-1b functions as an oncogenic factor in mouse melanoma cells. Journal of Dermatological Science 105:3, pages 159-169.
Crossref
Crossref
Guoxiang Rong, Zhongjun Pan, Ming Ding & Lihui Wang. (2021)
RNF168
suppresses the cancer stem cell‐like traits of nonsmall cell lung cancer cells by mediating
RhoC
ubiquitination
. Environmental Toxicology 37:3, pages 603-611.
Crossref
Crossref
Jae-Sung Yi, Sravan Perla & Anton M. Bennett. (2022) An Assessment of the Therapeutic Landscape for the Treatment of Heart Disease in the RASopathies. Cardiovascular Drugs and Therapy.
Crossref
Crossref
Zimo Jia, Jiaqi An, Ziyuan Liu & Fan Zhang. (2022) Non-Coding RNAs in Colorectal Cancer: Their Functions and Mechanisms. Frontiers in Oncology 12.
Crossref
Crossref
Shilpa Kuttikrishnan, Kirti S. Prabhu, Ahmed H. Al Sharie, Yazan O. Al Zu'bi, Feras Q. Alali, Nicholas H. Oberlies, Aamir Ahmad, Tamam El-Elimat & Shahab Uddin. (2022) Natural resorcylic acid lactones: A chemical biology approach for anticancer activity. Drug Discovery Today 27:2, pages 547-557.
Crossref
Crossref
Guoliang Zhang, Bing Li & Yuanmei Lin. (2022) Evaluation of ITGA3 as a Biomarker of Progression and Recurrence in Papillary Thyroid Carcinoma. Frontiers in Oncology 11.
Crossref
Crossref
Usman Sanwal, Thai Son Hoang, Luigia Petre & Ion Petre. (2022) Scalable reaction network modeling with automatic validation of consistency in Event-B. Scientific Reports 12:1.
Crossref
Crossref
Bastian Ulmer, Margarete Odenthal, Reinhard Buettner, Wilfried Roth & Michael Kloth. (2022) Diffusion kernel-based predictive modeling of KRAS dependency in KRAS wild type cancer cell lines. npj Systems Biology and Applications 8:1.
Crossref
Crossref
Hui Zhang, Xu Zhang, Weiguo Xu & Jian Wang. (2022) TMC5 is Highly Expressed in Human Cancers and Corelates to Prognosis and Immune Cell Infiltration: A Comprehensive Bioinformatics Analysis. Frontiers in Molecular Biosciences 8.
Crossref
Crossref
Natália Meneses Araújo, Ileana Gabriela Sanchez Rubio, Nicholas Pietro Agulha Toneto, Mirian Galliote Morale & Rodrigo Esaki Tamura. (2022) The use of adenoviral vectors in gene therapy and vaccine approaches. Genetics and Molecular Biology 45:3 suppl 1.
Crossref
Crossref
Lubna Therachiyil, Anjana Anand, Abdullah Azmi, Ajaz Bhat, Hesham M. Korashy & Shahab Uddin. (2022) Role of RAS signaling in ovarian cancer. F1000Research 11, pages 1253.
Crossref
Crossref
Ting Xu, Xicheng Wang, Zhenghang Wang, Ting Deng, Changsong Qi, Dan Liu, Yanyan Li, Congcong Ji, Jian Li & Lin Shen. (2022) Molecular mechanisms underlying the resistance of BRAF V600E-mutant metastatic colorectal cancer to EGFR/BRAF inhibitors. Therapeutic Advances in Medical Oncology 14, pages 175883592211050.
Crossref
Crossref
Fang-Yuan Zhang, Run-Ze Li, Cong Xu, Xing-Xing Fan, Jia-Xin Li, Wei-Yu Meng, Xuan-Run Wang, Tu-Liang Liang, Xiao-Xiang Guan, Hu-Dan Pan, Liang Liu, Xiao-Jun Yao, Qi Biao Wu & Elaine Lai-Han Leung. (2022) Emodin induces apoptosis and suppresses non-small-cell lung cancer growth via downregulation of sPLA2-IIa. Phytomedicine 95, pages 153786.
Crossref
Crossref
David Planchard, Benjamin Besse, Harry J.M. Groen, Sayed M.S. Hashemi, Julien Mazieres, Tae Min Kim, Elisabeth Quoix, Pierre-Jean Souquet, Fabrice Barlesi, Christina Baik, Liza C. Villaruz, Ronan J. Kelly, Shirong Zhang, Monique Tan, Eduard Gasal, Libero Santarpia & Bruce E. Johnson. (2022) Phase 2 Study of Dabrafenib Plus Trametinib in Patients With BRAF V600E-Mutant Metastatic NSCLC: Updated 5-Year Survival Rates and Genomic Analysis. Journal of Thoracic Oncology 17:1, pages 103-115.
Crossref
Crossref
Ali Khader, Rozan Bokhari, Reza Hakimelahi, Christopher Scheirey, Jalil Afnan, Marta Braschi-Amirfarzan & Richard Thomas. (2022) A radiologist’s guide to novel anticancer therapies in the era of precision medicine. European Journal of Radiology Open 9, pages 100406.
Crossref
Crossref
Adolfo G. Mauro, Katherine Hunter & Fadi N. Salloum. 2022. Strategies to Mitigate the Toxicity of Cancer Therapeutics. Strategies to Mitigate the Toxicity of Cancer Therapeutics
167
214
.
Kirti Agrawal, Saniya Arfin, Manish K. Mishra, Sitaram Harihar, Kavindra Kumar Kesari, Shubhadeep Roychoudhury & Dhruv Kumar. 2022. Autophagy and Metabolism. Autophagy and Metabolism
119
140
.
Sabeeha Ali, Manzar Alam & Md. Imtaiyaz Hassan. 2022. Protein Kinase Inhibitors. Protein Kinase Inhibitors
1
22
.
Sadia Parveen, Hanfa Ashfaq, Mehak Shahid, Ambreen Kanwal & Asima Tayyeb. (2021) Emerging Therapeutic Role of CDK Inhibitors in Targeting Cancer Stem Cells. Journal of Biomedical Research & Environmental Sciences 2:11, pages 1111-1116.
Crossref
Crossref
Ying Zhao, Jianfei Pan, Chunwei Cao, Xiaojuan Liang, Shulin Yang, Lulu Liu, Cong Tao, Jianguo Zhao & Yanfang Wang. (2021) RNF20 affects porcine adipocyte differentiation via regulation of mitotic clonal expansion. Cell Proliferation 54:12.
Crossref
Crossref
Shan Zhu, Wenhui Jiao, Yanglu Xu, Lanjiao Hou, Hui Li, Jingrong Shao, Xiaoliang Zhang, Ran Wang & Dexin Kong. (2021) Palmitic acid inhibits prostate cancer cell proliferation and metastasis by suppressing the PI3K/Akt pathway. Life Sciences 286, pages 120046.
Crossref
Crossref
Ali Attiq, Lui Jin Yao, Sheryar Afzal & Mansoor Ali Khan. (2021) The triumvirate of NF-κB, inflammation and cytokine storm in COVID-19. International Immunopharmacology 101, pages 108255.
Crossref
Crossref
S. Udhaya Kumar & C. George Priya Doss. (2021) Computational investigation to identify potent inhibitors of the GTPase-Kirsten RAt sarcoma virus (K-Ras) mutants G12C and G12D. Computers in Biology and Medicine 139, pages 104946.
Crossref
Crossref
Maoduo Zhang, Ying Yi Zhang, Yongze Chen, Jia Wang, Qiang Wang & Hezhe Lu. (2021) TGF-β Signaling and Resistance to Cancer Therapy. Frontiers in Cell and Developmental Biology 9.
Crossref
Crossref
Puangwan Lapthanasupkul, Tuntikorn Laosuk, Preecha Ruangvejvorachai, Anchisa Aittiwarapoj & Nakarin Kitkumthorn. (2021) Frequency of BRAF V600E mutation in a group of Thai patients with ameloblastomas. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 132:5, pages e180-e185.
Crossref
Crossref
Fabiola Lilí Sarmiento-Salinas, Andrea Perez-Gonzalez, Adilene Acosta-Casique, Adrián Ix-Ballote, Alfonso Diaz, Samuel Treviño, Nora Hilda Rosas-Murrieta, Lourdes Millán-Perez-Peña & Paola Maycotte. (2021) Reactive oxygen species: Role in carcinogenesis, cancer cell signaling and tumor progression. Life Sciences 284, pages 119942.
Crossref
Crossref
Displaying 200 of 624 citing articles. Use the download link below to view the full list of citing articles.
Download full citations list