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Adiposopathy: how do diet, exercise and weight loss drug therapies improve metabolic disease in overweight patients?

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Pages 871-895 | Published online: 10 Jan 2014

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Agnieszka Wojciechowska-Kulik, Edyta Blus, Zbigniew Kowalczyk, Zbigniew Baj & Ewa Majewska. (2020) The Effect of Noninvasive Bariatric Surgery on the Levels of Certain Adipokines and Atherosclerosis Risk Factors in Patients with Metabolic Syndrome. Journal of the American College of Nutrition 39:6, pages 481-487.
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Kalaivani A.V. V. Sathibabu Uddandrao, Brahmanaidu Parim, Saravanan Ganapathy, Nivedha P. R.Sushma Chandulee Kancharla, Rameshreddy P.Swapna K.Vadivukkarasi Sasikumar. (2019) Reversal of high fat diet-induced obesity through modulating lipid metabolic enzymes and inflammatory markers expressions in rats. Archives of Physiology and Biochemistry 125:3, pages 228-234.
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A. Kalaivani, V. V. Sathibabu Uddandrao, P. Brahmanaidu, Ganapathy Saravanan, P. R. Nivedha, P. Tamilmani, K. Swapna & Sasikumar Vadivukkarasi. (2018) Anti obese potential of Cucurbita maxima seeds oil: effect on lipid profile and histoarchitecture in high fat diet induced obese rats. Natural Product Research 32:24, pages 2950-2953.
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Jean M Whaley, Mark Tirmenstein, Timothy P Reilly, Simon M Poucher, JoAnne Saye, Shamik Parikh & James F List. (2012) Targeting the kidney and glucose excretion with dapagliflozin: preclinical and clinical evidence for SGLT2 inhibition as a new option for treatment of type 2 diabetes mellitus. Diabetes, Metabolic Syndrome and Obesity 5, pages 135-148.
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Harold E Bays. (2011) Lorcaserin: drug profile and illustrative model of the regulatory challenges of weight-loss drug development. Expert Review of Cardiovascular Therapy 9:3, pages 265-277.
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Harold E Bays. (2009) Lorcaserin and adiposopathy: 5-HT2c agonism as a treatment for ‘sick fat’ and metabolic disease. Expert Review of Cardiovascular Therapy 7:11, pages 1429-1445.
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Marcio C Mancini & Alfredo Halpern. (2008) Orlistat in the prevention of diabetes in the obese patient. Vascular Health and Risk Management 4:2, pages 325-336.
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Harold E Bays, Ann P Tighe, Richard Sadovsky & Michael H Davidson. (2008) Prescription omega-3 fatty acids and their lipid effects: physiologic mechanisms of action and clinical implications. Expert Review of Cardiovascular Therapy 6:3, pages 391-409.
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Harold E Bays, J Michael González-Campoy, George A Bray, Abbas E Kitabchi, Donald A Bergman, Alan Bruce Schorr, Helena W Rodbard & Robert R Henry. (2008) Pathogenic potential of adipose tissue and metabolic consequences of adipocyte hypertrophy and increased visceral adiposity. Expert Review of Cardiovascular Therapy 6:3, pages 343-368.
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André J Scheen. (2008) The future of obesity: new drugs versus lifestyle interventions. Expert Opinion on Investigational Drugs 17:3, pages 263-267.
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Jozef Ukropec, Barbara Ukropcova, Timea Kurdiova, Daniela Gasperikova & Iwar Klimes. (2008) Adipose tissue and skeletal muscle plasticity modulates metabolic health. Archives of Physiology and Biochemistry 114:5, pages 357-368.
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Harold Bays & Peter H Jones. (2007) Colesevelam hydrochloride: reducing atherosclerotic coronary heart disease risk factors. Vascular Health and Risk Management 3:5, pages 733-742.
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Steven K. Malin & Sangeeta R. Kashyap. (2016) Effects of various gastrointestinal procedures on β-cell function in obesity and type 2 diabetes. Surgery for Obesity and Related Diseases 12:6, pages 1213-1219.
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Indriyanti Rafi Sukmawati & Andi Wijaya. (2013) Adiposopathy and Obesity Paradox. The Indonesian Biomedical Journal 5:1, pages 3.
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Jennifer K. Pepping, Linnea R. Freeman, Sunita Gupta, Jeffrey N. Keller & Annadora J. Bruce-Keller. (2013) NOX2 deficiency attenuates markers of adiposopathy and brain injury induced by high-fat diet. American Journal of Physiology-Endocrinology and Metabolism 304:4, pages E392-E404.
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Swathi Appachi, Karen R. Kelly, Philip R. Schauer, John P. Kirwan, Stanley Hazen, Manjula Gupta & Sangeeta R. Kashyap. (2011) Reduced Cardiovascular Risk Following Bariatric Surgeries is Related to a Partial Recovery from “Adiposopathy”. Obesity Surgery 21:12, pages 1928-1936.
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S.M. Somerset, L. Graham & K. Markwell. (2011) Depression scores predict adherence in a dietary weight loss intervention trial. Clinical Nutrition 30:5, pages 593-598.
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H. E. Bays, J. M. Gonzalez-Campoy & A. B. Schorr. (2010) What men should know about metabolic syndrome, adiposopathy and ‘sick fat’. International Journal of Clinical Practice 64:13, pages 1735-1739.
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Yu-Wen Huang, Yue Liu, Slavik Dushenkov, Chi-Tang Ho & Mou-Tuan Huang. (2009) Anti-obesity effects of epigallocatechin-3-gallate, orange peel extract, black tea extract, caffeine and their combinations in a mouse model. Journal of Functional Foods 1:3, pages 304-310.
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Kavitha Bhat Schelbert. (2009) Comorbidities of Obesity. Primary Care: Clinics in Office Practice 36:2, pages 271-285.
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Harold E. Bays. (2009) “Sick Fat,” Metabolic Disease, and Atherosclerosis. The American Journal of Medicine 122:1, pages S26-S37.
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Makoto Horikawa, Toshihisa Nomura, Teppei Hashimoto & Kazuichi Sakamoto. (2008) Elongation and Desaturation of Fatty Acids are Critical in Growth, Lipid Metabolism and Ontogeny of Caenorhabditis elegans. The Journal of Biochemistry 144:2, pages 149-158.
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Carlo Maria Rotella & Laura Pala. (2008) Time to insulin in type-2 diabetes: high hurdles or Santiago way?. Acta Diabetologica 45:2, pages 67-74.
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A. J. Scheen. (2008) CB1 Receptor Blockade and its Impact on Cardiometabolic Risk Factors: Overview of the RIO Programme with Rimonabant. Journal of Neuroendocrinology 20:s1, pages 139-146.
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D. Mafra, F. Guebre-Egziabher & D. Fouque. (2008) Body mass index, muscle and fat in chronic kidney disease: questions about survival. Nephrology Dialysis Transplantation 23:8, pages 2461-2466.
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Jason M. Hollander & Jeffrey I. Mechanick. (2008) Complementary and Alternative Medicine and the Management of the Metabolic Syndrome. Journal of the American Dietetic Association 108:3, pages 495-509.
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Olivia Sánchez Sánchez & José Sabán Ruiz. (2008) Luces y sombras en la aplicación de las nuevas guías para el tratamiento de la diabetes mellitus tipo 2. Consejos prácticos sobre el tratamiento combinado y la insulinoterapia. Medicina Clínica 130:5, pages 188-196.
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Josep Vidal & Ramón Gomis. (2008) Interrelaciones entre obesidad y aterotrombosis. Revista Española de Cardiología Suplementos 8:3, pages 3C-11C.
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Harold E Bays & Ronald B Goldberg. (2007) The ‘Forgotten’ Bile Acid Sequestrants: Is Now a Good Time to Remember?. American Journal of Therapeutics 14:6, pages 567-580.
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Harold BaysJennifer McElhattanBrian S Bryzinski. (2016) A double-blind, randomised trial of tesaglitazar versus pioglitazone in patients with type 2 diabetes mellitus. Diabetes and Vascular Disease Research 4:3, pages 181-193.
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Harold Bays, Helena W. Rodbard, Alan Bruce Schorr & J. Michael González-Campoy. (2007) Adiposopathy: Treating pathogenic adipose tissue to reduce cardiovascular disease risk. Current Treatment Options in Cardiovascular Medicine 9:4, pages 259-271.
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H. E. Bays, R. H. Chapman & S. Grandy. (2007) The relationship of body mass index to diabetes mellitus, hypertension and dyslipidaemia: comparison of data from two national surveys. International Journal of Clinical Practice 61:5, pages 737-747.
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Julie A. Lovegrove. (2007) CVD risk in South Asians: the importance of defining adiposity and influence of dietary polyunsaturated fat. Proceedings of the Nutrition Society 66:2, pages 286-298.
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