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Research Articles

Heat exposure enhances radiosensitivity by depressing DNA-PK kinase activity during double strand break repair

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Pages 102-109 | Received 01 Jun 2013, Accepted 22 Jan 2014, Published online: 26 Feb 2014

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H. P. Kok, G. C. van Rhoon, T. D. Herrera, J. Overgaard & J. Crezee. (2022) Biological modeling in thermoradiotherapy: present status and ongoing developments toward routine clinical use. International Journal of Hyperthermia 39:1, pages 1126-1140.
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Ji Woon Yea, Jae Won Park, Se An Oh & Jaehyeon Park. (2021) Chemoradiotherapy with hyperthermia versus chemoradiotherapy alone in locally advanced cervical cancer: a systematic review and meta-analysis. International Journal of Hyperthermia 38:1, pages 1333-1340.
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Makoto Ihara, Kazuko Shichijo, Takashi Kudo & Kenzo Ohtsuka. (2019) Reactivation of heat-inactivated Ku proteins by heat shock cognate protein HSC73. International Journal of Hyperthermia 36:1, pages 437-442.
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Yosuke Nakagawa, Atsuhisa Kajihara, Akihisa Takahashi, Akiho S. Murata, Masaya Matsubayashi, Soichiro S. Ito, Ichiro Ota, Takahiko Nakagawa, Masatoshi Hasegawa, Tadaaki Kirita, Takeo Ohnishi & Eiichiro Mori. (2018) BRCA2 protects mammalian cells from heat shock. International Journal of Hyperthermia 34:6, pages 795-801.
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Arlene L. Oei, Vidhula R. Ahire, C. M. van Leeuwen, Rosemarie ten Cate, Lukas J. A. Stalpers, Johannes Crezee, H. Petra Kok & Nicolaas A. P. Franken. (2018) Enhancing radiosensitisation of BRCA2-proficient and BRCA2-deficient cell lines with hyperthermia and PARP1-i. International Journal of Hyperthermia 34:1, pages 39-48.
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Akihisa Takahashi, Eiichiro Mori, Yosuke Nakagawa, Atsuhisa Kajihara, Tadaaki Kirita, Douglas L. Pittman, Masatoshi Hasegawa & Takeo Ohnishi. (2017) Homologous recombination preferentially repairs heat-induced DNA double-strand breaks in mammalian cells. International Journal of Hyperthermia 33:3, pages 336-342.
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Nathalie van den Tempel, Michael R. Horsman & Roland Kanaar. (2016) Improving efficacy of hyperthermia in oncology by exploiting biological mechanisms. International Journal of Hyperthermia 32:4, pages 446-454.
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Cihan Gani, Christopher Schroeder, Vanessa Heinrich, Patrick Spillner, Ulf Lamprecht, Bernhard Berger & Daniel Zips. (2016) Long-term local control and survival after preoperative radiochemotherapy in combination with deep regional hyperthermia in locally advanced rectal cancer. International Journal of Hyperthermia 32:2, pages 187-192.
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Michael R. Horsman. (2016) Realistic biological approaches for improving thermoradiotherapy. International Journal of Hyperthermia 32:1, pages 14-22.
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Imen Belhadj Slimen, Taha Najar, Abdeljelil Ghram, Hajer Dabbebi, Moncef Ben Mrad & Manef Abdrabbah. (2014) Reactive oxygen species, heat stress and oxidative-induced mitochondrial damage. A review. International Journal of Hyperthermia 30:7, pages 513-523.
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Irma Telarovic, Roland H. Wenger & Martin Pruschy. (2021) Interfering with Tumor Hypoxia for Radiotherapy Optimization. Journal of Experimental & Clinical Cancer Research 40:1.
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O. V. Shpileva, L. A. Kolomiets, Zh. A. Startseva & O. N. Churuksaeva. (2021) LOCAL HYPERTHERMIA IN THE TREATMNET OF LOCALLY ADVANCED CERVICAL CANCER: CURRENT VIEW ON THE PROBLEM. Siberian journal of oncology 20:4, pages 122-129.
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Shin-Hee Han, Jae Young Kim, June-Hee Lee & Chung-Mo Park. (2021) Safeguarding genome integrity under heat stress in plants. Journal of Experimental Botany.
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Gary Hannon, Felista L. Tansi, Ingrid Hilger & Adriele Prina‐Mello. (2021) The Effects of Localized Heat on the Hallmarks of Cancer. Advanced Therapeutics 4:7, pages 2000267.
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Niloy R. Datta, H. Petra Kok, Hans Crezee, Udo S. Gaipl & Stephan Bodis. (2020) Integrating Loco-Regional Hyperthermia Into the Current Oncology Practice: SWOT and TOWS Analyses. Frontiers in Oncology 10.
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Niloy R. Datta & Stephan Bodis. (2019) Hyperthermia with radiotherapy reduces tumour alpha/beta: Insights from trials of thermoradiotherapy vs radiotherapy alone. Radiotherapy and Oncology 138, pages 1-8.
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Wen-Hui Yang, Jun Xie, Zhi-Yong Lai, Mu-Dan Yang, Ge-Hong Zhang, Yuan Li, Jian-Bing Mu & Jun Xu. (2019) Radiofrequency deep hyperthermia combined with chemotherapy in the treatment of advanced non-small cell lung cancer. Chinese Medical Journal 132:8, pages 922-927.
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Makoto Ihara, Kiyoto Ashizawa, Kazuko Shichijo & Takashi Kudo. (2019) Expression of the DNA-dependent protein kinase catalytic subunit is associated with the radiosensitivity of human thyroid cancer cell lines. Journal of Radiation Research 60:2, pages 171-177.
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Pernille Elming, Brita Sørensen, Arlene Oei, Nicolaas Franken, Johannes Crezee, Jens Overgaard & Michael Horsman. (2019) Hyperthermia: The Optimal Treatment to Overcome Radiation Resistant Hypoxia. Cancers 11:1, pages 60.
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Marloes IJff, Bregje van Oorschot, Arlene L. Oei, Przemek M. Krawczyk, Hans M. Rodermond, Lukas J. A. Stalpers, H. Petra Kok, Johannes Crezee & Nicolaas A. P. Franken. (2018) Enhancement of Radiation Effectiveness in Cervical Cancer Cells by Combining Ionizing Radiation with Hyperthermia and Molecular Targeting Agents. International Journal of Molecular Sciences 19:8, pages 2420.
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KEN OHNISHI. (2017) Effectiveness of Hyperthermia on Cancer Stem Cells. Thermal Medicine 33:2, pages 29-37.
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Theodora Mantso, George Goussetis, Rodrigo Franco, Sotiris Botaitis, Aglaia Pappa & Mihalis Panayiotidis. (2016) Effects of hyperthermia as a mitigation strategy in DNA damage-based cancer therapies. Seminars in Cancer Biology 37-38, pages 96-105.
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JUNKO MAEDA, YOSHIHIRO FUJII, HIROSHI FUJISAWA, HIROKAZU HIRAKAWA, IAN M. CARTWRIGHT, MITSURU UESAKA, HISASHI KITAMURA, AKIRA FUJIMORI & TAKAMITSU A. KATO. (2015) Hyperthermia-induced radiosensitization in CHO wild-type, NHEJ repair mutant and HR repair mutant following proton and carbon-ion exposure. Oncology Letters 10:5, pages 2828-2834.
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Kirsten Lauber, Nikko Brix, Anne Ernst, Roman Hennel, Julia Krombach, Heike Anders & Claus Belka. (2015) Targeting the heat shock response in combination with radiotherapy: Sensitizing cancer cells to irradiation-induced cell death and heating up their immunogenicity. Cancer Letters 368:2, pages 209-229.
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Kanwal Ahmed, Yoshiaki Tabuchi & Takashi Kondo. (2015) Hyperthermia: an effective strategy to induce apoptosis in cancer cells. Apoptosis 20:11, pages 1411-1419.
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Defeng Qi, Yuan Hu, Jinhui Li, Tao Peng, Jialin Su, Yun He & Weidong Ji. (2015) Hyperthermia Induces Apoptosis of 786-O Cells through Suppressing Ku80 Expression. PLOS ONE 10:4, pages e0122977.
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Kishan AT Naipal & Dik C van Gent. (2015) PARP inhibitors: the journey from research hypothesis to clinical approval. Personalized Medicine 12:2, pages 139-154.
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