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Original Article

Hot Topic: Can mild hyperthermia improve tumour oxygenation?

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Pages 141-147 | Received 17 Aug 1996, Accepted 07 Nov 1996, Published online: 09 Jul 2009

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Read on this site (24)

H. P. Kok, G. C. van Rhoon, T. D. Herrera, J. Overgaard & J. Crezee. (2022) Biological modeling in thermoradiotherapy: present status and ongoing developments toward routine clinical use. International Journal of Hyperthermia 39:1, pages 1126-1140.
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Hamzah Maswadeh, Arif Khan, Mohammed S. Alorainy, Naser A. Al-Wabel & Costas Demetzos. (2022) In vitro and in vivo activity of thermosensitive liposomes loaded with doxorubicin and cisplatin. Drug Development and Industrial Pharmacy 48:4, pages 158-168.
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Pernille B. Elming, Brita S. Sørensen, Harald Spejlborg, Jens Overgaard & Michael R. Horsman. (2021) Does the combination of hyperthermia with low LET (linear energy transfer) radiation induce anti-tumor effects equivalent to those seen with high LET radiation alone?. International Journal of Hyperthermia 38:1, pages 105-110.
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Navid Farr, Yak-Nam Wang, Samantha D’Andrea, Frank Starr, Ari Partanen, Kayla M. Gravelle, Jeannine S. McCune, Linda J. Risler, Stella G. Whang, Amy Chang, Sunil R. Hingorani, Donghoon Lee & Joo Ha Hwang. (2018) Hyperthermia-enhanced targeted drug delivery using magnetic resonance-guided focussed ultrasound: a pre-clinical study in a genetic model of pancreatic cancer. International Journal of Hyperthermia 34:3, pages 284-291.
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Nathalie van den Tempel, Michael R. Horsman & Roland Kanaar. (2016) Improving efficacy of hyperthermia in oncology by exploiting biological mechanisms. International Journal of Hyperthermia 32:4, pages 446-454.
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Zhi-Yuan Wang, Hui Zhang, Yang Yang, Xiang-Yang Xie, Yan-Fang Yang, Zhiping Li, Ying Li, Wei Gong, Fang-Lin Yu, Zhenbo Yang, Ming-Yuan Li & Xing-Guo Mei. (2016) Preparation, characterization, and efficacy of thermosensitive liposomes containing paclitaxel. Drug Delivery 23:4, pages 1222-1231.
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Gerard C. van Rhoon. (2016) Is CEM43 still a relevant thermal dose parameter for hyperthermia treatment monitoring?. International Journal of Hyperthermia 32:1, pages 50-62.
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Vladimir V. Kosterev, Evgeny A. Kramer-Ageev, Vladimir N. Mazokhin, Gerard C. van Rhoon & Johannes Crezee. (2015) Development of a novel method to enhance the therapeutic effect on tumours by simultaneous action of radiation and heating. International Journal of Hyperthermia 31:4, pages 443-452.
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Sun-Kyung Lim, Dae Hwan Shin, Mi-Hee Choi & Jin-Seok Kim. (2014) Enhanced antitumor efficacy of gemcitabine-loaded temperature-sensitive liposome by hyperthermia in tumor-bearing mice. Drug Development and Industrial Pharmacy 40:4, pages 470-476.
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Bilyana M Dicheva & Gerben A Koning. (2014) Targeted thermosensitive liposomes: an attractive novel approach for increased drug delivery to solid tumors. Expert Opinion on Drug Delivery 11:1, pages 83-100.
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Sumeeta Varma, Robert Myerson, Eduardo Moros, Marie Taylor, William Straube & Imran Zoberi. (2012) Simultaneous radiotherapy and superficial hyperthermia for high-risk breast carcinoma: A randomised comparison of treatment sequelae in heated versus non-heated sectors of the chest wall hyperthermia. International Journal of Hyperthermia 28:7, pages 583-590.
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Sunil Krishnan, Parmeswaran Diagaradjane & Sang Hyun Cho. (2010) Nanoparticle-mediated thermal therapy: Evolving strategies for prostate cancer therapy. International Journal of Hyperthermia 26:8, pages 775-789.
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Peter W. Vaupel & Debra K. Kelleher. (2010) Pathophysiological and vascular characteristics of tumours and their importance for hyperthermia: Heterogeneity is the key issue. International Journal of Hyperthermia 26:3, pages 211-223.
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Steffen L. Hokland, Thomas Nielsen, Morten Busk & Michael R. Horsman. (2010) Imaging tumour physiology and vasculature to predict and assess response to heat. International Journal of Hyperthermia 26:3, pages 264-272.
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Baris E. Dayanc, Sarah H. Beachy, Julie R. Ostberg & Elizabeth A. Repasky. (2008) Dissecting the role of hyperthermia in natural killer cell mediated anti-tumor responses. International Journal of Hyperthermia 24:1, pages 41-56.
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Yan Xu, Jason Choi, Bonnie Hylander, Arindam Sen, Sharon S. Evans, William G. Kraybill & Elizabeth A. Repasky. (2007) Fever-range whole body hyperthermia increases the number of perfused tumor blood vessels and therapeutic efficacy of liposomally encapsulated doxorubicin. International Journal of Hyperthermia 23:6, pages 513-527.
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. (2006) Letter to the editor. International Journal of Hyperthermia 22:5, pages 433-447.
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Michael R. Horsman. (2006) Tissue physiology and the response to heat. International Journal of Hyperthermia 22:3, pages 197-203.
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Robert J. Myerson, Anurag K. Singh, Heather M. Bigott, Bibiana Cha, John A. Engelbach, Joonyoung Kim, Wayne T. Lamoreaux, Eduardo Moros, Petr Novak, Terry L. Sharp, William Straube, Michael J. Welch & Mai Xu. (2006) Monitoring the effect of mild hyperthermia on tumour hypoxia by Cu-ATSM PET scanning. International Journal of Hyperthermia 22:2, pages 93-115.
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Robert J. Griffin, Atsushi Ogawa, Brent W. Williams & Chang W. Song. (2005) Hyperthermic Enhancement of Tumor Radiosensitization Strategies. Immunological Investigations 34:3, pages 343-359.
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Z. Vujaskovic & C. W. Song. (2004) Physiological mechanisms underlying heat-induced radiosensitization. International Journal of Hyperthermia 20:2, pages 163-174.
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R. J. Myerson, J. L. Roti Roti, E. G. Moros, W. L. Straube & M. Xu. (2004) Modelling heat-induced radiosensitization: clinical implications. International Journal of Hyperthermia 20:2, pages 201-212.
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F. M. Waterman, L. Komarnicky & D. B. Leeper. (1998) The response of human tumour blood flow to a fractionated course of thermoradiotherapy. International Journal of Hyperthermia 14:5, pages 421-434.
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Pernille Elming, Brita Sørensen, Arlene Oei, Nicolaas Franken, Johannes Crezee, Jens Overgaard & Michael Horsman. (2019) Hyperthermia: The Optimal Treatment to Overcome Radiation Resistant Hypoxia. Cancers 11:1, pages 60.
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Shiyu Gao, Min Zheng, Xiaohua Ren, Yaling Tang & Xinhua Liang. (2016) Local hyperthermia in head and neck cancer: mechanism, application and advance. Oncotarget 7:35, pages 57367-57378.
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V V Kardumyan, N A Aksenova, A A Chernyak, N N Glagolev, V I Volkov & A B Solovieva. (2015) The influence of temperature on the photo-oxidation rate of tryptophan in the presence of complexes of porphyrins with amphiphilic polymers. Laser Physics 25:4, pages 046002.
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Gabriella Hegyi, Gyula P. Szigeti & András Szász. (2013) Hyperthermia versus Oncothermia: Cellular Effects in Complementary Cancer Therapy. Evidence-Based Complementary and Alternative Medicine 2013, pages 1-12.
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Xiaorong Sun, Xiao-Feng Li, James Russell, Ligang Xing, Muneyasu Urano, Gloria C. Li, John L. Humm & C. Clifton Ling. (2008) Changes in tumor hypoxia induced by mild temperature hyperthermia as assessed by dual-tracer immunohistochemistry. Radiotherapy and Oncology 88:2, pages 269-276.
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Chikara Kunisaki, Hiroshi Shimada, Masato Nomura, Hirotoshi Akiyama, Masazumi Takahashi & Goro Matsuda. (2002) Lack of efficacy of prophylactic continuous hyperthermic peritoneal perfusion on subsequent peritoneal recurrence and survival in patients with advanced gastric cancer. Surgery 131:5, pages 521-528.
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A Ressel, O Schmitt, C Weiss & T Feyerabend. (2002) Therapeutic outcome and side-effects after radiotherapy, chemotherapy and/or hyperthermia treatment of head and neck tumour xenografts. European Journal of Cancer 38:4, pages 594-601.
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Chang W. Song, Heonjoo Park & Robert J. Griffin. (2001) Improvement of Tumor Oxygenation by Mild Hyperthermia. Radiation Research 155:4, pages 515-528.
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Zeljko Vujaskovic, Jean M Poulson, Amanda A Gaskin, Donald E Thrall, Rodney L Page, H.Cecil Charles, James R MacFall, David M Brizel, Robert E Meyer, Deborah M Prescott, Thaddeus V Samulski & M.W Dewhirst. (2000) Temperature-dependent changes in physiologic parameters of spontaneous canine soft tissue sarcomas after combined radiotherapy and hyperthermia treatment. International Journal of Radiation Oncology*Biology*Physics 46:1, pages 179-185.
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Dag R Olsen, Trond E Singstad & Einar K Rofstad. (1999) Effects of hyperthermia on bioenergetic status and phosphorus T1S in human melanoma xenografts monitored by 31P-MRS. Magnetic Resonance Imaging 17:7, pages 1049-1056.
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Robert B. Roemer. (1999) Engineering Aspects of Hyperthermia Therapy. Annual Review of Biomedical Engineering 1:1, pages 347-376.
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A. Orenstein, G. Kostenich, Y. Kopolovic, T. Babushkina & Z. Malik. (2008) Enhancement of ALA‐PDT Damage by IR‐lnduced Hyperthermia on a Colon Carcinoma Model. Photochemistry and Photobiology 69:6, pages 703-707.
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Abdus Shakil, James L Osborn & Chang W Song. (1999) Changes in oxygenation status and blood flow in a rat tumor model by mild temperature hyperthermia. International Journal of Radiation Oncology*Biology*Physics 43:4, pages 859-865.
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Eric Lartigau & Marcelle Guichard. 1999. Antiangiogenic Agents in Cancer Therapy. Antiangiogenic Agents in Cancer Therapy 23 35 .
Robert J Griffin, Kaoru Okajima & Chang W Song. (1998) The optimal combination of hyperthermia and carbogen breathing to increase tumor oxygenation and radiation response. International Journal of Radiation Oncology*Biology*Physics 42:4, pages 865-869.
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