Breast Cancer: Targets and Therapy, Volume 14, Issue (2022)

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Breast Cancer: Targets and Therapy, Volume 14, Issue (2022)

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Review

Review Article
Central Nervous System Metastases from Triple-Negative Breast Cancer: Current Treatments and Future Prospective
Arun Kadamkulam Syriac, Nitish Singh Nandu & Jose Pablo Leone
Pages: 1-13
Published online: 10 Jan 2022
AbstractforCentral Nervous System Metastases from Triple-Negative Breast Cancer: Current Treatments and Future Prospective | Full Text | References | PDF (456.5 KB) | EPUB
  • 906 Views
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Review Article
Treatment Strategies Against Triple-Negative Breast Cancer: An Updated Review
Mudasir Maqbool, Firomsa Bekele & Ginenus Fekadu
Pages: 15-24
Published online: 11 Jan 2022
AbstractforTreatment Strategies Against Triple-Negative Breast Cancer: An Updated Review | Full Text | References | PDF (927.8 KB) | EPUB
  • 2107 Views
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Original Research

Article
miR-101-5p Acts as a Tumor Suppressor in HER2-Positive Breast Cancer Cells and Improves Targeted Therapy
Lisa Svartdal Normann, Mads Haugland Haugen, Miriam Ragle Aure, Vessela N Kristensen, Gunhild Mari Mælandsmo & Kristine Kleivi Sahlberg
Pages: 25-39
Published online: 01 Mar 2022
AbstractformiR-101-5p Acts as a Tumor Suppressor in HER2-Positive Breast Cancer Cells and Improves Targeted Therapy | Full Text | References | PDF (6.3 MB) | EPUB
  • 580 Views
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Review

Review Article
Micropapillary Breast Carcinoma: From Molecular Pathogenesis to Prognosis
Georgios-Ioannis Verras, Levan Tchabashvili, Francesk Mulita, Ioanna Maria Grypari, Sofia Sourouni, Evangelia Panagodimou & Maria-Ioanna Argentou
Pages: 41-61
Published online: 12 Mar 2022
AbstractforMicropapillary Breast Carcinoma: From Molecular Pathogenesis to Prognosis | Full Text | References | PDF (2.6 MB) | EPUB
  • 723 Views
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Original Research

Article
Weekly vs Every-3-Week Carboplatin with Weekly Paclitaxel in Neoadjuvant Chemotherapy for Triple-Negative Breast Cancer: A Retrospective Analysis
Kara K Landry, Jessica L Lyon, Kitty E Victoria, P Nick Changizzadeh, Bernard F Cole, Bhargavi Pulluri, William M Sikov & Marie E Wood
Pages: 63-70
Published online: 15 Mar 2022
AbstractforWeekly vs Every-3-Week Carboplatin with Weekly Paclitaxel in Neoadjuvant Chemotherapy for Triple-Negative Breast Cancer: A Retrospective Analysis | Full Text | References | PDF (239.6 KB) | EPUB
  • 311 Views
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Review

Review Article
Polyethyleneimine (PEI) as a Polymer-Based Co-Delivery System for Breast Cancer Therapy
Alistia Ilmiah Fahira, Riezki Amalia, Melisa Intan Barliana, Vesara Ardhe Gatera & Rizky Abdulah
Pages: 71-83
Published online: 08 Apr 2022
AbstractforPolyethyleneimine (PEI) as a Polymer-Based Co-Delivery System for Breast Cancer Therapy | Full Text | References | PDF (2.2 MB) | EPUB
  • 969 Views
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Original Research

Article
Cross-Platform in-silico Analyses Exploring Tumor Immune Microenvironment with Prognostic Value in Triple-Negative Breast Cancer
Victor C Kok, Charles C N Wang, Szu-Han Liao & De-Lun Chen
Pages: 85-99
Published online: 12 Apr 2022
AbstractforCross-Platform in-silico Analyses Exploring Tumor Immune Microenvironment with Prognostic Value in Triple-Negative Breast Cancer | Full Text | References | PDF (6.7 MB) | EPUB
  • 410 Views
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Review

Review Article
Ribociclib in the Treatment of Hormone-Receptor Positive/HER2-Negative Advanced and Early Breast Cancer: Overview of Clinical Data and Patients Selection
Maria Chiara Parati, Rebecca Pedersini, Gianluca Perego, Roberto Reduzzi, Tommaso Savio, Mary Cabiddu, Karen Borgonovo, Mara Ghilardi, Andrea Luciani & Fausto Petrelli
Pages: 101-111
Published online: 12 Apr 2022
AbstractforRibociclib in the Treatment of Hormone-Receptor Positive/HER2-Negative Advanced and Early Breast Cancer: Overview of Clinical Data and Patients Selection | Full Text | References | PDF (381 KB) | EPUB
  • 337 Views
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Review Article
Targeted Treatment for High-Risk Early-Stage Triple-Negative Breast Cancer: Spotlight on Pembrolizumab
Nusayba A Bagegni, Andrew A Davis, Katherine K Clifton & Foluso O Ademuyiwa
Pages: 113-123
Published online: 29 Apr 2022
AbstractforTargeted Treatment for High-Risk Early-Stage Triple-Negative Breast Cancer: Spotlight on Pembrolizumab | Full Text | References | PDF (423.4 KB) | EPUB
  • 968 Views
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Original Research

Article
Breast Cancer in Italy: Stage and Region Distribution
Lucia Mangone, Isabella Bisceglia, Maria Michiara, Antonino Musolino, Guido Mazzoleni, Adele Caldarella, Sante Minerba, Giuseppe Cascone, Francesca Bella, Ylenia Dinaro, Loredana Pau & Carmine Pinto
Pages: 125-131
Published online: 29 Apr 2022
AbstractforBreast Cancer in Italy: Stage and Region Distribution | Full Text | References | PDF (626.8 KB) | EPUB
  • 393 Views
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Article
The Predictive Effect of the 8th AJCC Pathological Prognostic Staging on the Benefit of Postmastectomy Radiotherapy in N2/N3 Breast Cancer
Shi-Ping Yang, Ping Zhou, Chen-Lu Lian, Zhen-Yu He & San-Gang Wu
Pages: 133-144
Published online: 13 May 2022
AbstractforThe Predictive Effect of the 8th AJCC Pathological Prognostic Staging on the Benefit of Postmastectomy Radiotherapy in N2/N3 Breast Cancer | Full Text | References | PDF (4.3 MB) | EPUB
  • 265 Views
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Case Report

Case Report
Occult Invasive Lobular Carcinoma Presenting as an Axillary Skin Metastatic Lesion Underwent Neoadjuvant Endocrine Therapy and Surgical Resection: A Case Report and Review of Literature
Saleh Busbait, Abdullah M Alkhalifa, Shahad Aljohani & Hiyam Alhaddad
Pages: 145-152
Published online: 31 May 2022
AbstractforOccult Invasive Lobular Carcinoma Presenting as an Axillary Skin Metastatic Lesion Underwent Neoadjuvant Endocrine Therapy and Surgical Resection: A Case Report and Review of Literature | Full Text | References | PDF (824.8 KB) | EPUB
  • 345 Views
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Original Research

Article
The Effect of Estrogen Receptor Status on Survival in Breast Cancer Patients in Ethiopia. Retrospective Cohort Study
Abebe Muche Belete, Yared Asmare Aynalem, Belete Negese Gemeda, Tefera Mulugeta Demelew & Wondimeneh Shibabaw Shiferaw
Pages: 153-161
Published online: 17 Jun 2022
AbstractforThe Effect of Estrogen Receptor Status on Survival in Breast Cancer Patients in Ethiopia. Retrospective Cohort Study | Full Text | References | PDF (916.7 KB) | EPUB
  • 371 Views
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Review

Review Article
Cancer Treatment-Induced Bone Loss: Role of Denosumab in Non-Metastatic Breast Cancer
Boman Dhabhar
Pages: 163-173
Published online: 14 Jul 2022
AbstractforCancer Treatment-Induced Bone Loss: Role of Denosumab in Non-Metastatic Breast Cancer | Full Text | References | PDF (3.1 MB) | EPUB
  • 543 Views
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ORIGINAL RESEARCH

Article
Establishment and Validation of a Model for Disease-Free Survival Rate Prediction Using the Combination of microRNA-381 and Clinical Indicators in Patients with Breast Cancer
Jun Shen, Meng Wang, Fan Li, Huanhuan Yan, Rui Wang & Jun Zhou
Pages: 375-389
Published online: 04 Dec 2023
AbstractforEstablishment and Validation of a Model for Disease-Free Survival Rate Prediction Using the Combination of microRNA-381 and Clinical Indicators in Patients with Breast Cancer | Full Text | References | PDF (9.5 MB) | EPUB
  • 87 Views
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Article
Metformin Inducing the Change of Functional and Exhausted Phenotypic Tumor-Infiltrated Lymphocytes and the Correlation with JNK Signal Pathway in Triple-Negative Breast Cancer
Ruibin Wang, Yuchen Li, Yanjie Zhao, Feng Shi, Quan Zhou, Jiangping Wu, Shuzhen Lyu & Qingkun Song
Pages: 391-403
Published online: 04 Dec 2023
AbstractforMetformin Inducing the Change of Functional and Exhausted Phenotypic Tumor-Infiltrated Lymphocytes and the Correlation with JNK Signal Pathway in Triple-Negative Breast Cancer | Full Text | References | PDF (9.3 MB) | EPUB
  • 106 Views
  • 1 CrossRef citations
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Open Access
Article
Pyrotinib for Elderly Patients with Advanced HER2-Positive Breast Cancer
Yan Li, Xiaoping Ma, Zhenhui Zhao, Li Li, Chunyan Gao, Dan Liu, Bingyu Li & Bing Zhao
Pages: 405-415
Published online: 04 Dec 2023
AbstractforPyrotinib for Elderly Patients with Advanced HER2-Positive Breast Cancer | Full Text | References | PDF (4.4 MB) | EPUB
  • 76 Views
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Article
Effect of Chemotherapy on the Gut Microbiome of Breast Cancer Patients During the First Year of Treatment
Anna H Wu, Cheryl Vigen, Chiuchen Tseng, Agustin A Garcia & Darcy Spicer
Pages: 433-451
Published online: 04 Dec 2023
AbstractforEffect of Chemotherapy on the Gut Microbiome of Breast Cancer Patients During the First Year of Treatment | Full Text | References | PDF (3.1 MB) | EPUB
  • 227 Views
  • 3 CrossRef citations
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Article
Economic Evaluation of Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer in the United States
Yitian Lang, Bin Wu & Xiaoyan Liu
Pages: 453-463
Published online: 04 Dec 2023
AbstractforEconomic Evaluation of Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer in the United States | Full Text | References | PDF (600.9 KB) | EPUB
  • 151 Views
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REVIEW

Review
Advances in Antibody-Drug Conjugates in the Treatment of HER2-Positive Breast Cancer
Yongchao Yu, Jin Wang, Dongying Liao, Dou Zhang, Xiaojiang Li, Yingjie Jia & Fanming Kong
Pages: 417-432
Published online: 04 Dec 2023
AbstractforAdvances in Antibody-Drug Conjugates in the Treatment of HER2-Positive Breast Cancer | Full Text | References | PDF (564.9 KB) | EPUB
  • 158 Views
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Review
Advances in Single-Cell Sequencing Technology and Its Applications in Triple-Negative Breast Cancer
Meng Li, Tingting Yan, Miaozhou Wang, Yanqiu Cai & Yingyuan Wei
Pages: 465-474
Published online: 04 Dec 2023
AbstractforAdvances in Single-Cell Sequencing Technology and Its Applications in Triple-Negative Breast Cancer | Full Text | References | PDF (410.9 KB) | EPUB
  • 99 Views
  • 1 CrossRef citations
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ORIGINAL RESEARCH

Article
Real-World Outcome and Prognostic Factors Among HER2-Positive Metastatic Breast Cancer Patients Receiving Pyrotinib-Based Therapy: A Multicenter Retrospective Analysis
Jing Liu, Xianglu Sun, Qianyu Du, Jinghao Yao, Mengfen Dai, Qianqian Cheng, Han Xu, Yawei Li, Xiuli Liu, Mingliang Zhang, Yongchun Zhou & Yan Yang
Pages: 491-504
Published online: 04 Dec 2023
AbstractforReal-World Outcome and Prognostic Factors Among HER2-Positive Metastatic Breast Cancer Patients Receiving Pyrotinib-Based Therapy: A Multicenter Retrospective Analysis | Full Text | References | PDF (6.7 MB) | EPUB
  • 128 Views
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LETTER

Factors Predicting Positive Sentinel Lymph Node Biopsy in Clinically Node-Negative Breast Cancer [Letter]
Jia-Yu Zhang & Bao-Hua Xu
Pages: 489-490
Published online: 04 Dec 2023
CitationforFactors Predicting Positive Sentinel Lymph Node Biopsy in Clinically Node-Negative Breast Cancer [Letter] | Full Text | References | PDF (293 KB) | EPUB
  • 68 Views
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ORIGINAL RESEARCH

Article
Predictive and Prognostic Value of TRIM58 Protein Expression in Patients with Breast Cancer Receiving Neoadjuvant Chemotherapy
Yi-Zi Zheng, Jia-Ying Li, Lv-Wen Ning & Ni Xie
Pages: 475-487
Published online: 04 Dec 2023
AbstractforPredictive and Prognostic Value of TRIM58 Protein Expression in Patients with Breast Cancer Receiving Neoadjuvant Chemotherapy | Full Text | References | PDF (6.4 MB) | EPUB
  • 124 Views
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Article
Whole Genome Sequencing of Single-Circulating Tumor Cell Ameliorates Unraveling Breast Cancer Heterogeneity
Yongping Li, Xiaofei Jiang, Ming Zhong, Bo Yu & Hao Yuan
Pages: 505-513
Published online: 04 Dec 2023
AbstractforWhole Genome Sequencing of Single-Circulating Tumor Cell Ameliorates Unraveling Breast Cancer Heterogeneity | Full Text | References | PDF (4.6 MB) | EPUB
  • 117 Views
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Article
Chromobox Family Proteins as Putative Biomarkers for Breast Cancer Management: A Preliminary Study Based on Bioinformatics Analysis and qRT-PCR Validation
Hao Tian, Tingting Zhao, Yanling Li, Na Sun, Dandan Ma, Qiyun Shi, Guozhi Zhang, Qingqiu Chen, Kongyong Zhang, Ceshi Chen, Yi Zhang & Xiaowei Qi
Pages: 515-535
Published online: 04 Dec 2023
AbstractforChromobox Family Proteins as Putative Biomarkers for Breast Cancer Management: A Preliminary Study Based on Bioinformatics Analysis and qRT-PCR Validation | Full Text | References | PDF (21.3 MB) | EPUB
  • 114 Views
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REVIEW

Review
The Notch Signaling Pathway Contributes to Angiogenesis and Tumor Immunity in Breast Cancer
Nina Jiang, Ye Hu, Meiling Wang, Zuowei Zhao & Man Li
Pages: 291-309
Published online: 04 Dec 2023
AbstractforThe Notch Signaling Pathway Contributes to Angiogenesis and Tumor Immunity in Breast Cancer | Full Text | References | PDF (2.9 MB) | EPUB
  • 234 Views
  • 1 CrossRef citations
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CASE SERIES

Ribociclib Plus Letrozole in Italian Male Patients with Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer: Case Studies of Phase 3b CompLEEment-1 Trial
Roberta Caputo, Alessandra Fabi, Emanuela Romagnoli, Editta Baldini, Donatella Grasso, Nicola Fenderico & Andrea Michelotti
Pages: 351-362
Published online: 04 Dec 2023
AbstractforRibociclib Plus Letrozole in Italian Male Patients with Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer: Case Studies of Phase 3b CompLEEment-1 Trial | Full Text | References | PDF (1.5 MB) | EPUB
  • 138 Views
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REVIEW

Review
Evaluating the Fragility of Long-Term Outcomes for Neoadjuvant versus Adjuvant Chemotherapy Prescription in Early Breast Cancer: Pooled Data from 10 Randomised Clinical Trials
Matthew G Davey & Michael J Kerin
Pages: 343-350
Published online: 04 Dec 2023
AbstractforEvaluating the Fragility of Long-Term Outcomes for Neoadjuvant versus Adjuvant Chemotherapy Prescription in Early Breast Cancer: Pooled Data from 10 Randomised Clinical Trials | Full Text | References | PDF (1.6 MB) | EPUB
  • 106 Views
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ORIGINAL RESEARCH

Article
Is Routine Intraoperative Frozen Section Analysis of Sentinel Lymph Nodes Necessary in Every Early-Stage Breast Cancer?
Bhoowit Lerttiendamrong, Nattanan Treeratanapun, Voranaddha Vacharathit, Kasaya Tantiphlachiva, Phuphat Vongwattanakit, Sopark Manasnayakorn & Mawin Vongsaisuwon
Pages: 281-290
Published online: 04 Dec 2023
AbstractforIs Routine Intraoperative Frozen Section Analysis of Sentinel Lymph Nodes Necessary in Every Early-Stage Breast Cancer? | Full Text | References | PDF (1.2 MB) | EPUB
  • 145 Views
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Article
Development and Validation of an MRI Radiomics-Based Signature to Predict Histological Grade in Patients with Invasive Breast Cancer
Shihui Wang, Yi Wei, Zhouli Li, Jingya Xu & Yunfeng Zhou
Pages: 335-342
Published online: 04 Dec 2023
AbstractforDevelopment and Validation of an MRI Radiomics-Based Signature to Predict Histological Grade in Patients with Invasive Breast Cancer | Full Text | References | PDF (3.8 MB) | EPUB
  • 98 Views
  • 4 CrossRef citations
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Article
Clinical Characteristics and Survival Outcomes of Patients with De Novo Metastatic Breast Cancer
Hanan Almasri, Ayah Erjan, Hebah Abudawaba, Khaled Ashouri, Sara Mheid, Anoud Alnsour & Hikmat Abdel-Razeq
Pages: 363-373
Published online: 04 Dec 2023
AbstractforClinical Characteristics and Survival Outcomes of Patients with De Novo Metastatic Breast Cancer | Full Text | References | PDF (1.2 MB) | EPUB
  • 140 Views
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REVIEW

Review
Heart Sparing Radiotherapy Techniques in Breast Cancer: A Focus on Deep Inspiration Breath Hold
Hayley B Stowe, Neal D Andruska, Francisco Reynoso, Maria Thomas & Carmen Bergom
Pages: 175-186
Published online: 04 Dec 2023
AbstractforHeart Sparing Radiotherapy Techniques in Breast Cancer: A Focus on Deep Inspiration Breath Hold | Full Text | References | PDF (3.1 MB) | EPUB
  • 407 Views
  • 4 CrossRef citations
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ORIGINAL RESEARCH

Article
Ovo Like Zinc Finger 2 (OVOL2) Suppresses Breast Cancer Stem Cell Traits and Correlates with Immune Cells Infiltration
Jiafa Wu, Dongping Luo & Shengnan Li
Pages: 211-227
Published online: 04 Dec 2023
AbstractforOvo Like Zinc Finger 2 (OVOL2) Suppresses Breast Cancer Stem Cell Traits and Correlates with Immune Cells Infiltration | Full Text | References | PDF (5.6 MB) | EPUB
  • 159 Views
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Open Access
Article
miR-623 Targets Metalloproteinase-1 and Attenuates Extravasation of Brain Metastatic Triple-Negative Breast Cancer Cells
Dua Hammash, Mona Mahfood, Ghalia Khoder, Munazza Ahmed, Abdelaziz Tlili, Rifat Hamoudi & Rania Harati
Pages: 187-198
Published online: 04 Dec 2023
AbstractformiR-623 Targets Metalloproteinase-1 and Attenuates Extravasation of Brain Metastatic Triple-Negative Breast Cancer Cells | Full Text | References | PDF (4.5 MB) | EPUB
  • 136 Views
  • 3 CrossRef citations
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Article
A Real-World Data Retrospective Cohort Study of Low Estrogen Receptor-Positive Early Breast Cancer: Natural History and Treatment Outcomes
Shahla Bari, David Boulware, Jiannong Li, Loretta Loftus, Aixa Soyano Muller, Zena Jameel, Hung Khong, Brian J Czerniecki & Ricardo LB Costa
Pages: 199-210
Published online: 04 Dec 2023
AbstractforA Real-World Data Retrospective Cohort Study of Low Estrogen Receptor-Positive Early Breast Cancer: Natural History and Treatment Outcomes | Full Text | References | PDF (2.9 MB) | EPUB
  • 131 Views
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REVIEW

Review
A Scoping Review on the Status of Female Breast Cancer in Asia with a Special Focus on Nepal
Rojana Dhakal, Maria Noula, Zoe Roupa & Edna N Yamasaki
Pages: 229-246
Published online: 04 Dec 2023
AbstractforA Scoping Review on the Status of Female Breast Cancer in Asia with a Special Focus on Nepal | Full Text | References | PDF (2.6 MB) | EPUB
  • 328 Views
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ORIGINAL RESEARCH

Article
Chloride Intracellular Channel 1 is a Potential Biomarker for Breast Cancer
Jinwen Xia, Quhui Wang, Fei Ju, Xiang Luo, Feng Wang, Youlang Zhou, Hua Huang, Hua Wang & Xingli Bao
Pages: 247-258
Published online: 04 Dec 2023
AbstractforChloride Intracellular Channel 1 is a Potential Biomarker for Breast Cancer | Full Text | References | PDF (4.7 MB) | EPUB
  • 105 Views
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Open Access
Article
Breast Cancer Subtypes and Prognosis: Answers to Subgroup Classification Questions, Identifying the Worst Subgroup in Our Single-Center Series
Rusen Cosar, Necdet Sut, Alaattin Ozen, Ebru Tastekin, Sernaz Topaloglu, Irfan Cicin, Dilek Nurlu, Talar Ozler, Seda Demir, Gokay Yıldız, Eylül Şenödeyici & Mustafa Cem Uzal
Pages: 259-280
Published online: 04 Dec 2023
AbstractforBreast Cancer Subtypes and Prognosis: Answers to Subgroup Classification Questions, Identifying the Worst Subgroup in Our Single-Center Series | Full Text | References | PDF (3.4 MB) | EPUB
  • 114 Views
  • 2 CrossRef citations
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Article
Factors Predicting Positive Sentinel Lymph Node Biopsy in Clinically Node-Negative Breast Cancer
Thuraya S Alsumai, Norah Alhazzaa, Abdullah Alshamrani, Sarah Assiri & Amal Alhefdhi
Pages: 323-334
Published online: 04 Dec 2023
AbstractforFactors Predicting Positive Sentinel Lymph Node Biopsy in Clinically Node-Negative Breast Cancer | Full Text | References | PDF (339.3 KB) | EPUB
  • 247 Views
  • 2 CrossRef citations
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Article
The Involvement of Insulin-Like Growth Factor 2 Messenger Ribonucleic Acid-Binding Protein 2 in the Regulation of the Expression of Breast Cancer-Related Genes
Chao Gao, Li Li, Xixin Jin, Xinyu Song, Huiling Li, Xiaoli Xu, Chao Dong & Binlin Ma
Pages: 311-322
Published online: 04 Dec 2023
AbstractforThe Involvement of Insulin-Like Growth Factor 2 Messenger Ribonucleic Acid-Binding Protein 2 in the Regulation of the Expression of Breast Cancer-Related Genes | Full Text | References | PDF (6.3 MB) | EPUB
  • 186 Views
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