Pharmacogenomics and Personalized Medicine, Volume 4, Issue (2011)

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Pharmacogenomics and Personalized Medicine, Volume 4, Issue (2011)

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Review

Review Article
Optimizing response to gefitinib in the treatment of non-small-cell lung cancer
Pietro Carotenuto, Cristin Roma, Anna Maria Rachiglio, Raffaella Pasquale, Renato Franco, Giuseppe Antinolfi, Francovito Piantedosi, Alfonso Illiano, Gerardo Botti, Alessandro Morabito, Nicola Normanno & Antonella De Luca
Pages: 1-9
Published online: 14 Mar 2011
AbstractforOptimizing response to gefitinib in the treatment of non-small-cell lung cancer | Full Text | References | PDF (199.9 KB)
  • 56 Views
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Open Access
Review Article
Pharmacogenomics of drug metabolizing enzymes and transporters: implications for cancer therapy
Jing Li & Martin H Bluth
Pages: 11-33
Published online: 01 Apr 2011
AbstractforPharmacogenomics of drug metabolizing enzymes and transporters: implications for cancer therapy | Full Text | References | PDF (411.2 KB)
  • 177 Views
  • 16 CrossRef citations
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Open Access

Original Research

Article
A genetic approach to the prediction of drug side effects: bleomycin induces concordant phenotypes in mice of the collaborative cross
Richard Gelinas, Elissa J Chesler, Daphne Vasconcelos, Darla R Miller, Yue Yuan, Kai Wang & David Galas
Pages: 35-45
Published online: 04 Jul 2011
AbstractforA genetic approach to the prediction of drug side effects: bleomycin induces concordant phenotypes in mice of the collaborative cross | Full Text | References | PDF (2.3 MB)
  • 63 Views
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Review

Review Article
ERCC1 and XRCC1 as biomarkers for lung and head and neck cancer
Alec Vaezi, Chelsea H Feldman & Laura J Niedernhofer
Pages: 47-63
Published online: 20 Jul 2011
AbstractforERCC1 and XRCC1 as biomarkers for lung and head and neck cancer | Full Text | References | PDF (671.8 KB)
  • 78 Views
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Open Access

Case Series and Review

Case Report
Antidepressant-induced akathisia-related homicides associated with diminishing mutations in metabolizing genes of the CYP450 family
Yolande Lucire & Christopher Crotty
Pages: 65-81
Published online: 01 Aug 2011
AbstractforAntidepressant-induced akathisia-related homicides associated with diminishing mutations in metabolizing genes of the CYP450 family | Full Text | References | PDF (314.8 KB)
  • 291 Views
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Review

Review Article
Role of 5-HT2C receptor gene variants in antipsychotic-induced weight gain
Tessa JM Wallace, Clement C Zai, Eva J Brandl & Daniel J Müller
Pages: 83-93
Published online: 18 Aug 2011
AbstractforRole of 5-HT2C receptor gene variants in antipsychotic-induced weight gain | Full Text | References | PDF (195.5 KB)
  • 96 Views
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Open Access
Review Article
Clinical implementation of RNA signatures for pharmacogenomic decision-making
Weihua Tang, Zhiyuan Hu, Hind Muallem & Margaret L Gulley
Pages: 95-107
Published online: 08 Sep 2011
AbstractforClinical implementation of RNA signatures for pharmacogenomic decision-making | Full Text | References | PDF (1.6 MB)
  • 59 Views
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Open Access
Review Article
Clinical application of high throughput molecular screening techniques for pharmacogenomics
Arun P Wiita & Iris Schrijver
Pages: 109-121
Published online: 08 Sep 2011
AbstractforClinical application of high throughput molecular screening techniques for pharmacogenomics | Full Text | References | PDF (278.1 KB)
  • 100 Views
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Open Access
Review Article
Role of cytochrome P450 genotype in the steps toward personalized drug therapy
Larisa H Cavallari, Hyunyoung Jeong & Adam Bress
Pages: 123-136
Published online: 07 Nov 2011
AbstractforRole of cytochrome P450 genotype in the steps toward personalized drug therapy | Full Text | References | PDF (265 KB)
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Original Research

Article
Sulfation of fulvestrant by human liver cytosols and recombinant SULT1A1 and SULT1E1
Vineetha Koroth Edavana, Xinfeng Yu, Ishwori B Dhakal, Suzanne Williams, Baitang Ning, Ian T Cook, David Caldwell, Charles N Falany & Susan Kadlubar
Pages: 137-145
Published online: 17 Nov 2011
AbstractforSulfation of fulvestrant by human liver cytosols and recombinant SULT1A1 and SULT1E1 | Full Text | References | PDF (323.2 KB)
  • 132 Views
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