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Volume 19, Issue 12

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 19, Issue 12 (2023)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 19, Issue 12 (2023)

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Vol 20, 2024 Volume 19, 2023 Vol 18, 2022 Vol 17, 2021 Vol 16, 2020 Vol 15, 2019 Vol 14, 2018 Vol 13, 2017 Vol 12, 2016 Vol 11, 2015 Vol 10, 2014 Vol 9, 2013 Vol 8, 2012 Vol 7, 2011 Vol 6, 2010 Vol 5, 2009 Vol 4, 2008 Vol 3, 2007 Vol 2, 2006 Vol 1, 2005

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Editorial

What is the impact of type 2 diabetes mellitus on CYP450 metabolic activities?

Brian Tomlinson & Yan-Hong Li

Pages: 867-870

Published online: 12 Jan 2024

First Page PreviewforWhat is the impact of type 2 diabetes mellitus on CYP450 metabolic activities? | Full Text | References | PDF (172.1 KB) | EPUB

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Free Access

Drug Evaluation

Review Article

Combined oral contraceptive with estetrol plus drospirenone: from pharmacokinetics to clinical applications

Christian Battipaglia, Lia Feliciello, Alessandro D. Genazzani, Fabio Facchinetti & Giovanni Grandi

Pages: 871-879

Published online: 12 Jan 2024

AbstractforCombined oral contraceptive with estetrol plus drospirenone: from pharmacokinetics to clinical applications | Full Text | References | PDF (3.1 MB) | EPUB

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Review Article

Pharmacokinetic evaluation of sofosbuvir/velpatasvir for the treatment of Chronic Hepatitis C in pediatrics aged 3 and older

Jessica Tuan, Adaora Okoli & Onyema Ogbuagu

Pages: 881-888

Published online: 12 Jan 2024

AbstractforPharmacokinetic evaluation of sofosbuvir/velpatasvir for the treatment of Chronic Hepatitis C in pediatrics aged 3 and older | Full Text | References | PDF (298.9 KB) | EPUB

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Review Article

A pharmacokinetic evaluation of tenapanor for the treatment of irritable bowel syndrome with constipation: an update of the literature

Diego Currò, Gianluca Ianiro & Antonio Gasbarrini

Pages: 889-894

Published online: 12 Jan 2024

AbstractforA pharmacokinetic evaluation of tenapanor for the treatment of irritable bowel syndrome with constipation: an update of the literature | Full Text | References | PDF (250.4 KB) | EPUB

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Review

Review Article

Overview of the pharmacokinetics and pharmacodynamics of URAT1 inhibitors for the treatment of hyperuricemia and gout

Zihan Hou, Aijinxiu Ma, Jiale Mao, Danni Song & Xu Zhao

Pages: 895-909

Published online: 12 Jan 2024

AbstractforOverview of the pharmacokinetics and pharmacodynamics of URAT1 inhibitors for the treatment of hyperuricemia and gout | Full Text | References | PDF (2.9 MB) | EPUB

284 Views
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Review Article

Pharmacokinetics and pharmacodynamics of direct oral anticoagulants

B. Hindley, G.Y.H. Lip, A.P. McCloskey & P.E. Penson

Pages: 911-923

Published online: 12 Jan 2024

AbstractforPharmacokinetics and pharmacodynamics of direct oral anticoagulants | Full Text | References | PDF (1.2 MB) | EPUB

3595 Views
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Open Access

Review Article

Drug-drug interactions between COVID-19 therapeutics and psychotropic medications

Alessandro Cuomo, Giovanni Barillà, Gianluca Serafini, Andrea Aguglia, Andrea Amerio, Matteo Cattolico, Pietro Carmellini, Alessandro Spiti & Andrea Fagiolini

Pages: 925-936

Published online: 12 Jan 2024

AbstractforDrug-drug interactions between COVID-19 therapeutics and psychotropic medications | Full Text | References | PDF (322.1 KB) | EPUB

118 Views
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Review Article

Drug-drug interactions between COVID-19 drug therapies and antidepressants

Efstathia Davoutis, Chrysa Panou, Nikolina Stachika, Christina Dalla & Nikolaos Kokras

Pages: 937-950

Published online: 12 Jan 2024

AbstractforDrug-drug interactions between COVID-19 drug therapies and antidepressants | Full Text | References | PDF (371.8 KB) | EPUB

124 Views
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Review Article

Metabolic and toxicological considerations regarding CGRP mAbs and CGRP antagonists to treat migraine in COVID-19 patients: a narrative review

Tsubasa Takizawa, Keiko Ihara, Shunsuke Uno, Seiya Ohtani, Narumi Watanabe, Noboru Imai, Jin Nakahara, Satoko Hori, David Garcia-Azorin & Paolo Martelletti

Pages: 951-967

Published online: 12 Jan 2024

AbstractforMetabolic and toxicological considerations regarding CGRP mAbs and CGRP antagonists to treat migraine in COVID-19 patients: a narrative review | Full Text | References | PDF (421.8 KB) | EPUB

259 Views
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Review Article

Review of human risk factors for idiosyncratic drug-induced liver injury: latest advances and future goals

Helgi Kristinn Björnsson & Einar Stefan Björnsson

Pages: 969-977

Published online: 12 Jan 2024

AbstractforReview of human risk factors for idiosyncratic drug-induced liver injury: latest advances and future goals | Full Text | References | PDF (321.7 KB) | EPUB

177 Views
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Review Article

Predicting the pharmacokinetics and pharmacodynamics of antisense oligonucleotides: an overview of various approaches and opportunities for PBPK/PD modelling

Xiang Gao, John K. Diep, Daniel A. Norris, Rosie Z. Yu & Richard S. Geary

Pages: 979-990

Published online: 12 Jan 2024

AbstractforPredicting the pharmacokinetics and pharmacodynamics of antisense oligonucleotides: an overview of various approaches and opportunities for PBPK/PD modelling | Full Text | References | PDF (1.5 MB) | EPUB

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Review Article

A systematic review on the clinical pharmacokinetics of vildagliptin in healthy and disease populations

Mahnoor Pasha, Ammara Zamir, Waseem Ashraf, Imran Imran, Hamid Saeed, Anees Ur Rehman, Majid Aziz, Faleh Alqahtani & Muhammad Fawad Rasool

Pages: 991-1003

Published online: 12 Jan 2024

113 Views
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Original Research

Article

CYP3A inhibitor itraconazole affect pharmacokinetic behavior of famitinib and its active metabolite: results of a single-center, single-arm, open-label and fixed sequence study

Yunzhe Huang, Yuanwei Jia, Xinyan Chen, Changmao Wang, Yaqin Wang, Minhui Wang, Ping Wu & Jie Shen

Pages: 1005-1013

Published online: 12 Jan 2024

AbstractforCYP3A inhibitor itraconazole affect pharmacokinetic behavior of famitinib and its active metabolite: results of a single-center, single-arm, open-label and fixed sequence study | Full Text | References | PDF (1.5 MB) | EPUB

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Article

Evaluation of bioequivalence and safety analysis of capecitabine tablets and Xeloda® under postprandial dosing conditions in Chinese patients with solid tumor

Hongtao Li, Rongfang Shan, Jiaxiang Ding, Jialin Zhang, Bingyan Liu, Qin Ge, Dongmei Cheng, Lufeng Li, Chaoyang Zhang, He Su, Xiaoyue Li, Huiru Li, Jingjing Ye, Hui Li, Fengxian Li, Huan Zhou, Qiang Huo & Yue Su

Pages: 1015-1021

Published online: 12 Jan 2024

AbstractforEvaluation of bioequivalence and safety analysis of capecitabine tablets and Xeloda® under postprandial dosing conditions in Chinese patients with solid tumor | Full Text | References | PDF (919.6 KB) | EPUB

788 Views
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Open Access

Article

Toxic metabolites and metabolic soft spots of celastrol based on glutathione metabolic capture and high-resolution mass spectrometry

Xiaojuan Jiang, Caixia Yuan, Rong Ding, Di Lu, Xiaoyu Peng, Zhihao Dong, Chunyan Zhu, Yihua Lin, Caisheng Wu & Qiang Xie

Pages: 1023-1032

Published online: 12 Jan 2024

AbstractforToxic metabolites and metabolic soft spots of celastrol based on glutathione metabolic capture and high-resolution mass spectrometry | Full Text | References | PDF (7 MB) | EPUB

62 Views
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Expert Opinion on Drug Metabolism & Toxicology (Vol.19, Iss.12, 2023)

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