Pharmaceutical Development and Technology, Volume 18, Issue 1 (2013)

Browse this journal
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Pharmaceutical Development and Technology, Volume 18, Issue 1 (2013)

See all volumes and issues
Vol 29, 2024 Vol 28, 2023 Vol 27, 2022 Vol 26, 2021 Vol 25, 2020 Vol 24, 2019 Vol 23, 2018 Vol 22, 2017 Vol 21, 2016 Vol 20, 2015 Vol 19, 2014 Volume 18, 2013 Vol 17, 2012 Vol 16, 2011 Vol 15, 2010 Vol 14, 2009 Vol 13, 2008 Vol 12, 2007 Vol 11, 2006 Vol 10, 2005 Vol 9, 2004-2005 Vol 8, 2003 Vol 7, 2002 Vol 6, 2001 Vol 5, 2000 Vol 4, 1999 Vol 3, 1998 Vol 2, 1997 Vol 1, 1996
Download citations Download PDFs Download issue

Editorial

Editorial
2013 Themed Issues for Pharmaceutical Development and Technology
Page: 1
Published online: 06 Dec 2012
Citationfor2013 Themed Issues for Pharmaceutical Development and Technology | Full Text | PDF (533.3 KB)
  • 539 Views
  • 0 CrossRef citations
  • 0Altmetric
Free Access

Review Article

Review Article
The reality of in-line tablet coating
Christine Cahyadi, Lai Wah Chan & Paul Wan Sia Heng
Pages: 2-16
Published online: 08 Jun 2011
AbstractforThe reality of in-line tablet coating | Full Text | References | PDF (908.9 KB)
  • 659 Views
  • 1 CrossRef citations
  • 0Altmetric
Review Article
Effects of pharmaceutical processing on pepsin activity during the formulation of solid dosage forms
Katalin Kristó & Klára Pintye-Hódi
Pages: 17-21
Published online: 06 Dec 2012
AbstractforEffects of pharmaceutical processing on pepsin activity during the formulation of solid dosage forms | Full Text | References | PDF (604.4 KB)
  • 196 Views
  • 3 CrossRef citations
  • 0Altmetric
Review Article
Supercritical fluid technology: a promising approach in pharmaceutical research
Priti Girotra, Shailendra Kumar Singh & Kalpana Nagpal
Pages: 22-38
Published online: 05 Oct 2012
AbstractforSupercritical fluid technology: a promising approach in pharmaceutical research | Full Text | References | PDF (788.1 KB)
  • 1595 Views
  • 117 CrossRef citations
  • 0Altmetric

Research Article

Article
Evaluating the process parameters of the dry coating process using a 25-1 factorial design
Caroline Désirée Kablitz & Nora Anne Urbanetz
Pages: 39-45
Published online: 19 Aug 2011
AbstractforEvaluating the process parameters of the dry coating process using a 25-1 factorial design | Full Text | References | PDF (880.8 KB)
  • 250 Views
  • 7 CrossRef citations
  • 0Altmetric
Article
Investigating the effect of punch geometry on high speed tableting through radial die-wall pressure monitoring
Sameh Abdel-Hamid & Gabriele Betz
Pages: 46-54
Published online: 03 Aug 2011
AbstractforInvestigating the effect of punch geometry on high speed tableting through radial die-wall pressure monitoring | Full Text | References | PDF (1.3 MB)
  • 300 Views
  • 4 CrossRef citations
  • 0Altmetric
Article
Effect of cocrystallization techniques on compressional properties of caffeine/oxalic acid 2:1 cocrystal
Suyog Aher, Ravindra Dhumal, Kakasaheb Mahadik, Jarkko Ketolainen & Anant Paradkar
Pages: 55-60
Published online: 10 Oct 2011
AbstractforEffect of cocrystallization techniques on compressional properties of caffeine/oxalic acid 2:1 cocrystal | Full Text | References | PDF (737.2 KB)
  • 500 Views
  • 18 CrossRef citations
  • 0Altmetric
Article
Insights into the functionality of pelletization aid in pelletization by extrusion-spheronization
Srimanta Sarkar, Paul W. S. Heng & Celine V. Liew
Pages: 61-72
Published online: 08 Oct 2011
AbstractforInsights into the functionality of pelletization aid in pelletization by extrusion-spheronization | Full Text | References | PDF (1.1 MB)
  • 390 Views
  • 11 CrossRef citations
  • 0Altmetric
Article
Focused beam reflectance method as an innovative (PAT) tool to monitor in-line granulation process in fluidized bed
Firas Alshihabi, Thierry Vandamme & Gabriele Betz
Pages: 73-84
Published online: 29 Oct 2011
AbstractforFocused beam reflectance method as an innovative (PAT) tool to monitor in-line granulation process in fluidized bed | Full Text | References | PDF (1.5 MB)
  • 605 Views
  • 20 CrossRef citations
  • 0Altmetric
Article
Real-time assessment of critical quality attributes of a continuous granulation process
Margot Fonteyne, Jurgen Vercruysse, Damián Córdoba Díaz, Delphine Gildemyn, Chris Vervaet, Jean Paul Remon & Thomas De Beer
Pages: 85-97
Published online: 24 Oct 2011
AbstractforReal-time assessment of critical quality attributes of a continuous granulation process | Full Text | References | PDF (1.4 MB)
  • 1871 Views
  • 92 CrossRef citations
  • 0Altmetric
Article
Evaluation of melt rheology of lactose-filled polyethylene glycol composites by means of capillary rheometery
Bahareh Bahramian, Ghodratollah H. Motlagh, Shabnam Majidi S, Babak Kaffashi, Seyed A. Nojoumi & Ismaeil Haririan
Pages: 98-105
Published online: 05 Dec 2011
AbstractforEvaluation of melt rheology of lactose-filled polyethylene glycol composites by means of capillary rheometery | Full Text | References | PDF (1.1 MB)
  • 160 Views
  • 6 CrossRef citations
  • 0Altmetric
Article
Flow rate and flow equation of pharmaceutical free-flowable powder excipients
Zdenka Šklubalová & Zdenek Zatloukal
Pages: 106-111
Published online: 10 Dec 2011
AbstractforFlow rate and flow equation of pharmaceutical free-flowable powder excipients | Full Text | References | PDF (624.3 KB)
  • 327 Views
  • 1 CrossRef citations
  • 0Altmetric
Article
Rheological evaluation of wet masses for the preparation of pharmaceutical pellets by capillary and rotational rheometers
Shabnam Majidi, Ghodratolah H. Motlagh, Bahareh Bahramian, Babak Kaffashi, Seyed A. Nojoumi & Ismaeil Haririan
Pages: 112-120
Published online: 22 Dec 2011
AbstractforRheological evaluation of wet masses for the preparation of pharmaceutical pellets by capillary and rotational rheometers | Full Text | References | PDF (1.3 MB)
  • 253 Views
  • 5 CrossRef citations
  • 0Altmetric
Article
Design of experiments utilization to map the processing capabilities of a micro-spray dryer: particle design and throughput optimization in support of drug discovery
James D. Ormes, Dan Zhang, Alex M. Chen, Shirley Hou, Davida Krueger, Todd Nelson & Allen Templeton
Pages: 121-129
Published online: 14 Mar 2012
AbstractforDesign of experiments utilization to map the processing capabilities of a micro-spray dryer: particle design and throughput optimization in support of drug discovery | Full Text | References | PDF (1.3 MB)
  • 528 Views
  • 18 CrossRef citations
  • 0Altmetric
Article
Enhanced dissolution, stability and physicochemical characterization of ATRA/2-hydroxypropyl-β-cyclodextrin inclusion complex pellets prepared by fluid-bed coating technique
Zhongjian Chen, Yi Lu, Jianping Qi & Wei Wu
Pages: 130-136
Published online: 05 Feb 2012
AbstractforEnhanced dissolution, stability and physicochemical characterization of ATRA/2-hydroxypropyl-β-cyclodextrin inclusion complex pellets prepared by fluid-bed coating technique | Full Text | References | PDF (768.6 KB)
  • 255 Views
  • 7 CrossRef citations
  • 0Altmetric
Article
Chitosan–kaolin coprecipitate as disintegrant in microcrystalline cellulose-based pellets elaborated by extrusion–spheronization
Alvaro Goyanes, Consuelo Souto & Ramón Martínez-Pacheco
Pages: 137-145
Published online: 07 Feb 2012
AbstractforChitosan–kaolin coprecipitate as disintegrant in microcrystalline cellulose-based pellets elaborated by extrusion–spheronization | Full Text | References | PDF (1.4 MB)
  • 193 Views
  • 11 CrossRef citations
  • 0Altmetric
Article
Characterization of critical physical and mechanical properties of freeze-dried grape powder for development of a clinical patient delivery system
Daniel Hu, Rahul V. Haware, Mazen L. Hamad & Kenneth R. Morris
Pages: 146-155
Published online: 15 Feb 2012
AbstractforCharacterization of critical physical and mechanical properties of freeze-dried grape powder for development of a clinical patient delivery system | Full Text | References | PDF (1.1 MB)
  • 154 Views
  • 4 CrossRef citations
  • 0Altmetric
Article
Assessing compressibility and compactibility of powder formulations with Near-Infrared Spectroscopy
Nicolaos D. Gentis, Branko Z. Vranic & Gabriele Betz
Pages: 156-171
Published online: 16 Apr 2012
AbstractforAssessing compressibility and compactibility of powder formulations with Near-Infrared Spectroscopy | Full Text | References | PDF (1.6 MB)
  • 586 Views
  • 1 CrossRef citations
  • 0Altmetric
Article
Characterization, optimisation and process robustness of a co-processed mannitol for the development of orally disintegrating tablets
Josephine Lay Peng Soh, Maud Grachet, Mark Whitlock & Timothy Lukas
Pages: 172-185
Published online: 14 May 2012
AbstractforCharacterization, optimisation and process robustness of a co-processed mannitol for the development of orally disintegrating tablets | Full Text | References | PDF (1.2 MB)
  • 738 Views
  • 14 CrossRef citations
  • 0Altmetric
Article
Oral transmucosal delivery of domperidone from immediate release films produced via hot-melt extrusion technology
Chinna Reddy Palem, Sunil Kumar Battu, Sindhuri Maddineni, Ramesh Gannu, Michael A. Repka & Madhusudan Rao Yamsani
Pages: 186-195
Published online: 13 Aug 2012
AbstractforOral transmucosal delivery of domperidone from immediate release films produced via hot-melt extrusion technology | Full Text | References | PDF (948.8 KB)
  • 543 Views
  • 38 CrossRef citations
  • 0Altmetric
Article
Microencapsulation of hydroxyzine HCl by thermal phase separation: in vitro release enhancement and in vivo pharmacodynamic evaluation
Christianne Mounir Zaki Rizkalla, Randa latif Aziz & Iman Ibrahim Soliman
Pages: 196-209
Published online: 05 Jun 2012
AbstractforMicroencapsulation of hydroxyzine HCl by thermal phase separation: in vitro release enhancement and in vivo pharmacodynamic evaluation | Full Text | References | PDF (1.4 MB)
  • 124 Views
  • 3 CrossRef citations
  • 0Altmetric
Article
A combined experimental and modeling approach to study the effects of high-shear wet granulation process parameters on granule characteristics
Preetanshu Pandey, Jing Tao, Anwesha Chaudhury, Rohit Ramachandran, Julia Z. Gao & Dilbir S. Bindra
Pages: 210-224
Published online: 11 Jul 2012
AbstractforA combined experimental and modeling approach to study the effects of high-shear wet granulation process parameters on granule characteristics | Full Text | References | PDF (1.9 MB)
  • 1067 Views
  • 49 CrossRef citations
  • 0Altmetric
Article
Multiple batch manufacturing of theophylline pellets using the wet-extrusion/spheronization process with κ-carrageenan as pelletisation aid
Cornelia Krueger & Markus Thommes
Pages: 225-235
Published online: 11 Jul 2012
AbstractforMultiple batch manufacturing of theophylline pellets using the wet-extrusion/spheronization process with κ-carrageenan as pelletisation aid | Full Text | References | PDF (953.2 KB)
  • 145 Views
  • 8 CrossRef citations
  • 0Altmetric
Article
A quality by design approach using artificial intelligence techniques to control the critical quality attributes of ramipril tablets manufactured by wet granulation
Buket Aksu, Anant Paradkar, Marcel de Matas, Özgen Özer, Tamer Güneri & Peter York
Pages: 236-245
Published online: 13 Aug 2012
AbstractforA quality by design approach using artificial intelligence techniques to control the critical quality attributes of ramipril tablets manufactured by wet granulation | Full Text | References | PDF (775 KB)
  • 1592 Views
  • 55 CrossRef citations
  • 0Altmetric
Article
Application of external lubrication during the roller compaction of adhesive pharmaceutical formulations
Jason Dawes, Carl Allenspach, John F. Gamble, Richard Greenwood, Phil Robbins & Mike Tobyn
Pages: 246-256
Published online: 20 Jul 2012
AbstractforApplication of external lubrication during the roller compaction of adhesive pharmaceutical formulations | Full Text | References | PDF (962.2 KB)
  • 492 Views
  • 9 CrossRef citations
  • 0Altmetric
Article
How suitable is the measurement of take-off forces for detection of sticking during direct compression of various ibuprofen tablet formulations?
Ines Saniocki, Albrecht Sakmann & Claudia S. Leopold
Pages: 257-265
Published online: 30 Aug 2012
AbstractforHow suitable is the measurement of take-off forces for detection of sticking during direct compression of various ibuprofen tablet formulations? | Full Text | References | PDF (917 KB)
  • 744 Views
  • 17 CrossRef citations
  • 0Altmetric
Article
Comparison of spray congealing and melt emulsification methods for the incorporation of the water-soluble salbutamol sulphate in lipid microparticles
Santo Scalia, Daniela Traini, Paul M. Young, Marcello Di Sabatino, Nadia Passerini & Beatrice Albertini
Pages: 266-273
Published online: 24 Sep 2012
AbstractforComparison of spray congealing and melt emulsification methods for the incorporation of the water-soluble salbutamol sulphate in lipid microparticles | Full Text | References | PDF (757.6 KB)
  • 270 Views
  • 13 CrossRef citations
  • 0Altmetric
Article
Effect of dirty-hold time on cleaning process of pharmaceutical equipment
Jan Patera, Gabriela Štípková, Petr Zámostný, Zdeněk Bělohlav & Zdeněk Vltavský
Pages: 274-279
Published online: 04 Oct 2012
AbstractforEffect of dirty-hold time on cleaning process of pharmaceutical equipment | Full Text | References | PDF (779.3 KB)
  • 481 Views
  • 1 CrossRef citations
  • 0Altmetric
Article
Quality by design: optimization of a freeze-drying cycle via design space in case of heterogeneous drying behavior and influence of the freezing protocol
Roberto Pisano, Davide Fissore, Antonello A. Barresi, Philippe Brayard, Pierre Chouvenc & Bertrand Woinet
Pages: 280-295
Published online: 19 Oct 2012
AbstractforQuality by design: optimization of a freeze-drying cycle via design space in case of heterogeneous drying behavior and influence of the freezing protocol | Full Text | References | PDF (1.5 MB)
  • 1005 Views
  • 66 CrossRef citations
  • 0Altmetric
Article
Processing challenges with solid dosage formulations containing vitamin E TPGS
Preetanshu Pandey, Patrick D. Sinko, Dilbir S. Bindra, Rhye Hamey, Shruti Gour & Chandra Vema-Varapu
Pages: 296-304
Published online: 09 Nov 2012
AbstractforProcessing challenges with solid dosage formulations containing vitamin E TPGS | Full Text | References | PDF (1.4 MB)
  • 495 Views
  • 20 CrossRef citations
  • 0Altmetric

Explore articles