Cell Cycle, Volume 10, Issue 6 (2011)

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Cell Cycle, Volume 10, Issue 6 (2011)

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Editorial
Vision in venture: Israel’s high-tech incubator program
Catarina Wylie
Pages: 855-858
Published online: 15 Mar 2011
AbstractforVision in venture: Israel’s high-tech incubator program | PDF (956.4 KB)
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Editorials: Cell Cycle Features

Editorial
Developmental regulation of replication-coupled protein destruction
Christina I. Swanson & Robert J. Duronio
Pages: 859-860
Published online: 15 Mar 2011
AbstractforDevelopmental regulation of replication-coupled protein destruction | PDF (384.5 KB)
  • 199 Views
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Editorial
The integral role of mTOR in lipid metabolism
Ghada A. Soliman
Pages: 861-862
Published online: 15 Mar 2011
AbstractforThe integral role of mTOR in lipid metabolism | Full Text | References | PDF (485 KB)
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Editorial
An ending is a new beginning: Transcription termination supports re-initiation
Søren Lykke-Andersen, Christophe K. Mapendano & Torben Heick Jensen
Pages: 863-865
Published online: 15 Mar 2011
AbstractforAn ending is a new beginning: Transcription termination supports re-initiation | PDF (972.1 KB)
  • 456 Views
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Editorial
E4F1 connects the Bmi1-ARF-p53 pathway to epidermal stem cell-dependent skin homeostasis
Julie Caramel, Matthieu Lacroix, Laurent O. Le Cam & Claude Sardet
Pages: 866-867
Published online: 15 Mar 2011
AbstractforE4F1 connects the Bmi1-ARF-p53 pathway to epidermal stem cell-dependent skin homeostasis | PDF (587.4 KB)
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Editorial
Tracking BAX once its trigger is pulled
Evripidis Gavathiotis & Loren D. Walensky
Pages: 868-870
Published online: 15 Mar 2011
AbstractforTracking BAX once its trigger is pulled | Full Text | References | PDF (1,022.5 KB)
  • 557 Views
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Editorial
Recent advances in chemically induced reprogramming
Saiyong Zhu, Tianhua Ma & Sheng Ding
Pages: 871-872
Published online: 15 Mar 2011
AbstractforRecent advances in chemically induced reprogramming | Full Text | References | PDF (441.3 KB)
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Cell Cycle News & Views

Subtle interactions between heterochromatin and DNA replication timing
Joel A. Huberman
Pages: 873-878
Published online: 15 Mar 2011
AbstractforSubtle interactions between heterochromatin and DNA replication timing | PDF (1.8 MB)
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Smc5 flies solo
Jordi Torres-Rosell & Ana Losada
Pages: 879-878
Published online: 15 Mar 2011
AbstractforSmc5 flies solo | PDF (1.8 MB)
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Pharmacological rescue of p53 in cancer cells: The soloist meets the PRIMA donna
Hind Hafsi & Pierre Hainaut
Pages: 879-878
Published online: 15 Mar 2011
AbstractforPharmacological rescue of p53 in cancer cells: The soloist meets the PRIMA donna | PDF (1.8 MB)
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An emerging function of survivin’s BIR domain phosphorylation in the control of cell division and cell death
Xavier Fant & Sandrine Ruchaud
Pages: 879-878
Published online: 15 Mar 2011
AbstractforAn emerging function of survivin’s BIR domain phosphorylation in the control of cell division and cell death | PDF (1.8 MB)
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Ndc80 complex: New evidence for the existence of spindle assembly checkpoint in mammalian oocyte meiosis
Qing-Yuan Sun
Pages: 879-878
Published online: 15 Mar 2011
AbstractforNdc80 complex: New evidence for the existence of spindle assembly checkpoint in mammalian oocyte meiosis | PDF (1.8 MB)
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Extra Views

Mechanism of hypoxia-induced NFκB
Andrew Melvin, Sharon Mudie & Sonia Rocha
Pages: 879-882
Published online: 15 Mar 2011
AbstractforMechanism of hypoxia-induced NFκB | Full Text | References | PDF (1 MB)
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Polycomb group proteins in the DNA damage response: A link between radiation resistance and “stemness”
Randall S. Gieni, Ismail H. Ismail, Stuart Campbell & Michael J. Hendzel
Pages: 883-894
Published online: 15 Mar 2011
AbstractforPolycomb group proteins in the DNA damage response: A link between radiation resistance and “stemness” | PDF (2.2 MB)
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Aurora kinases and spindle assembly: Variations on a common theme?
Vladimir Joukov
Pages: 895-903
Published online: 15 Mar 2011
AbstractforAurora kinases and spindle assembly: Variations on a common theme? | PDF (2.2 MB)
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Comparative transcriptional pathway bioinformatic analysis of dietary restriction, Sir2, p53 and resveratrol life span extension inDrosophila
Michael Antosh, Rachel Whitaker, Adam Kroll, Suzanne Hosier, Chengyi Chang, Johannes Bauer, Leon Cooper, Nicola Neretti & Stephen L. Helfand
Pages: 904-911
Published online: 15 Mar 2011
AbstractforComparative transcriptional pathway bioinformatic analysis of dietary restriction, Sir2, p53 and resveratrol life span extension inDrosophila | Full Text | References | PDF (4 MB) | Supplemental
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G1/S transcription and the DNA synthesis checkpoint: Common regulatory mechanisms
Tsvetomira Ivanova, Blanca Gómez-Escoda, Elena Hidalgo & José Ayté
Pages: 912-915
Published online: 15 Mar 2011
AbstractforG1/S transcription and the DNA synthesis checkpoint: Common regulatory mechanisms | PDF (907.8 KB)
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Perspective

How phosphorylation controls p53
Nicola J. Maclaine & Ted R. Hupp
Pages: 916-921
Published online: 15 Mar 2011
AbstractforHow phosphorylation controls p53 | PDF (1.6 MB)
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A precursor microRNA in a cancer cell nucleus
Get me out of here!
Sonia A. Melo & Manel Esteller
Pages: 922-925
Published online: 15 Mar 2011
AbstractforA precursor microRNA in a cancer cell nucleus | Full Text | References | PDF (938.7 KB)
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Report

Article
Crystal structure of the C-terminal domain of human DNA primase large subunit
Implications for the mechanism of the primase-polymerase α switch
Vinod B. Agarkar, Nigar D. Babayeva, Youri I. Pavlov & Tahir H. Tahirov
Pages: 926-931
Published online: 15 Mar 2011
AbstractforCrystal structure of the C-terminal domain of human DNA primase large subunit | Full Text | References | PDF (2.2 MB)
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Article
p21WAF1 is component of a positive feedback loop that maintains the p53 transcriptional program
Lisa Y. Pang, Mary Scott, Richard L. Hayward, Hisham Mohammed, C. Bruce A. Whitelaw, Graeme C.M. Smith & Ted R. Hupp
Pages: 932-950
Published online: 15 Mar 2011
Abstractforp21WAF1 is component of a positive feedback loop that maintains the p53 transcriptional program | PDF (8 MB)
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Article
Sgo1 is required for co-segregation of sister chromatids during achiasmate meiosis I
Andrej Dudas, Shazia Ahmad & Juraj Gregan
Pages: 951-955
Published online: 15 Mar 2011
AbstractforSgo1 is required for co-segregation of sister chromatids during achiasmate meiosis I | Full Text | References | PDF (1.3 MB)
  • 516 Views
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Article
A non-functional retinoblastoma tumor suppressor (RB) pathway in premenopausal breast cancer is associated with resistance to tamoxifen
Sophie Lehn, Mårten Fernö, Karin Jirström, Lisa Rydén & Göran Landberg
Pages: 956-962
Published online: 15 Mar 2011
AbstractforA non-functional retinoblastoma tumor suppressor (RB) pathway in premenopausal breast cancer is associated with resistance to tamoxifen | PDF (1.9 MB)
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Article
A first in man, phase I dose-escalation study of PHA-793887, an inhibitor of multiple cyclin-dependent kinases (CDK2, 1 and 4) reveals unexpected hepatotoxicity in patients with solid tumors 


Christophe Massard, Jean-Charles Soria, D. Alan Anthoney, A. Proctor, Angela Scaburri, Maria Adele Pacciarini, Bernard Laffranchi, Cinzia Pellizzoni, Guido Kroemer, Jean-Pierre Armand, Rastilav Balheda & Christopher J. Twelves
Pages: 963-970
Published online: 15 Mar 2011
AbstractforA first in man, phase I dose-escalation study of PHA-793887, an inhibitor of multiple cyclin-dependent kinases (CDK2, 1 and 4) reveals unexpected hepatotoxicity in patients with solid tumors 

 | PDF (1.3 MB)
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Article
Protein expression profiles of C3H 10T1/2 murine fibroblasts and of isogenic cells transformed by the H1047R mutant of phosphoinositide 3-kinase (PI3K)
Jonathan Ross Hart, Lujian Liao, Lynn Ueno, John R. Yates III & Peter K. Vogt
Pages: 971-976
Published online: 15 Mar 2011
AbstractforProtein expression profiles of C3H 10T1/2 murine fibroblasts and of isogenic cells transformed by the H1047R mutant of phosphoinositide 3-kinase (PI3K) | Full Text | References | PDF (1 MB) | Supplemental
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Article
Expression analysis and molecular targeting of cyclin-dependent kinases in advanced melanoma
Functional analysis and molecular targeting of cyclin-dependent kinase family members in advanced melanoma
Christopher Abdullah, Xiaolei Wang & Dorothea Becker
Pages: 977-988
Published online: 15 Mar 2011
AbstractforExpression analysis and molecular targeting of cyclin-dependent kinases in advanced melanoma | Full Text | References | PDF (11.5 MB)
  • 968 Views
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Article
Identification of dAven, a Drosophila melanogaster ortholog of the cell cycle regulator Aven
Identification of Drosophila Aven
Sige Zou, Joy Chang, Leesa LaFever, Wangli Tang, Erika L. Johnson, Jack Hu, Ronit Wilk, Henry M. Krause, Daniela Drummond-Barbosa & Pablo M. Irusta
Pages: 989-998
Published online: 15 Mar 2011
AbstractforIdentification of dAven, a Drosophila melanogaster ortholog of the cell cycle regulator Aven | Full Text | References | PDF (2.8 MB)
  • 617 Views
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Article
Stochastic exit from mitosis in budding yeast
Model predictions and experimental observations
David A. Ball, Tae-Hyuk Ahn, Pengyuan Wang, Katherine C. Chen, Yang Cao, John J. Tyson, Jean Peccoud & William T. Baumann
Pages: 999-1009
Published online: 15 Mar 2011
AbstractforStochastic exit from mitosis in budding yeast | Full Text | References | PDF (3.1 MB)
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Letter to the Editor

Letter
Novel alternatively spliced variant form of human CDK5RAP2
Tom Kim, John S.Y. Park, Paul Lee, Yan Jin, Song-bin Fu, Jesusa L. Rosales & Ki-Young Lee
Pages: 1010-1012
Published online: 15 Mar 2011
First Page PreviewforNovel alternatively spliced variant form of human CDK5RAP2 | Full Text | References | PDF (784.4 KB)
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