mAbs, Volume 2, Issue 3 (2010)

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mAbs, Volume 2, Issue 3 (2010)

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Editorial

Editorial
The Antibody Society
Andrew Bradbury
Page: 211
Published online: 01 May 2010
CitationforThe Antibody Society | Full Text | PDF (125.9 KB)
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Review

Review Article
Cleavage of IgGs by proteases associated with invasive diseases
an evasion tactic against host immunity?
Randall J. Brezski & Robert E. Jordan
Pages: 212-220
Published online: 01 May 2010
AbstractforCleavage of IgGs by proteases associated with invasive diseases | Full Text | References | PDF (423.2 KB)
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Review Article
Stability of IgG isotypes in serum
Ivan Correia
Pages: 221-232
Published online: 01 May 2010
AbstractforStability of IgG isotypes in serum | Full Text | References | PDF (2.6 MB)
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Review Article
Safety and immunotoxicity assessment of immunomodulatory monoclonal antibodies
Frank R. Brennan, Laura Dill Morton, Sebastian Spindeldreher, Andrea Kiessling, Roy Allenspach, Adam Hey, Patrick Müller, Werner Frings & Jennifer Sims
Pages: 233-255
Published online: 01 May 2010
AbstractforSafety and immunotoxicity assessment of immunomodulatory monoclonal antibodies | Full Text | References | PDF (1.9 MB)
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Report

Article
The immunogenicity of humanized and fully human antibodies
Residual immunogenicity resides in the CDR regions
Fiona A. Harding, Marcia M. Stickler, Jennifer Razo & Robert DuBridge
Pages: 256-265
Published online: 01 May 2010
AbstractforThe immunogenicity of humanized and fully human antibodies | Full Text | References | PDF (1.2 MB)
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Article
Potent and broad neutralizing activity of a single chain antibody fragment against cell-free and cell-associated HIV-1
Mei-Yun Zhang, Andrew Rosa Borges, Roger G. Ptak, Yanping Wang, Antony S. Dimitrov, S. Munir Alam, Lindsay Wieczorek, Peter Bouma, Timothy Fouts, Shibo Jiang, Victoria R. Polonis, Barton F. Haynes, Gerald V. Quinnan, David C. Montefiori & Dimiter S. Dimitrov
Pages: 266-274
Published online: 01 May 2010
AbstractforPotent and broad neutralizing activity of a single chain antibody fragment against cell-free and cell-associated HIV-1 | Full Text | References | PDF (606 KB)
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Article
Development and characterization of monoclonal antibodies against Rift Valley fever virus nucleocapsid protein generated by DNA immunization
Raquel Martín-Folgar, Gema Lorenzo, Hani Boshra, Javier Iglesias, Francisco Mateos, Belén Borrego & Alejandro Brun
Pages: 275-284
Published online: 01 May 2010
AbstractforDevelopment and characterization of monoclonal antibodies against Rift Valley fever virus nucleocapsid protein generated by DNA immunization | Full Text | References | PDF (1.6 MB)
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Article
Detecting low level sequence variants in recombinant monoclonal antibodies
Yi Yang, Alex Strahan, Charlene Li, Amy Shen, Hongbin Liu, Jun Ouyang, Viswanatham Katta, Kathleen Francissen & Boyan Zhang
Pages: 285-298
Published online: 01 May 2010
AbstractforDetecting low level sequence variants in recombinant monoclonal antibodies | Full Text | References | PDF (1.7 MB)
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Article
Identification of methionine sulfoxide diastereomers in immunoglobulin gamma antibodies using methionine sulfoxide reductase enzymes
Hui K. Khor, Michael E. Jacoby, Thomas C. Squier, Grace C. Chu & Dirk Chelius
Pages: 299-308
Published online: 01 May 2010
AbstractforIdentification of methionine sulfoxide diastereomers in immunoglobulin gamma antibodies using methionine sulfoxide reductase enzymes | Full Text | References | PDF (1.6 MB)
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Article
Structural and functional characterization of the trifunctional antibody catumaxomab
Dirk Chelius, Peter Ruf, Patrick Gruber, Matthias Plöscher, Reinhard Liedtke, Eva Gansberger, Juergen Hess, Michael Wasiliu & Horst Lindhofer
Pages: 309-319
Published online: 01 May 2010
AbstractforStructural and functional characterization of the trifunctional antibody catumaxomab | Full Text | References | PDF (1.1 MB)
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Article
Differences in N-glycan structures found on recombinant IgA1 and IgA2 produced in murine myeloma and CHO cell lines
Esther M. Yoo, Li J. Yu, Letitia A. Wims, David Goldberg & Sherie L. Morrison
Pages: 320-334
Published online: 01 May 2010
AbstractforDifferences in N-glycan structures found on recombinant IgA1 and IgA2 produced in murine myeloma and CHO cell lines | Full Text | References | PDF (4.1 MB)
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Article
In vitro potency, pharmacokinetic profiles and pharmacological activity of optimized anti-IL-21R antibodies in a mouse model of lupus
Yulia Vugmeyster, Heath Guay, Pamela Szklut, Ming D. Qian, Macy Jin, Angela Widom, Vikki Spaulding, Frann Bennett, Leslie Lowe, Tatyana Andreyeva, David C. Lowe, Steven Lane, George Thom, Viia Valge-Archer, Davinder Gill, Deborah Young & Laird Bloom
Pages: 335-346
Published online: 01 May 2010
AbstractforIn vitro potency, pharmacokinetic profiles and pharmacological activity of optimized anti-IL-21R antibodies in a mouse model of lupus | Full Text | References | PDF (1.6 MB) | Supplemental
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Perspective

Therapeutic antibodies, vaccines and antibodyomes
Dimiter S. Dimitrov
Pages: 347-356
Published online: 01 May 2010
AbstractforTherapeutic antibodies, vaccines and antibodyomes | Full Text | References | PDF (695.1 KB)
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Editor's Corner

Editorial
Upcoming meetings
Janice M. Reichert
Page: 357
Published online: 01 May 2010
CitationforUpcoming meetings | Full Text | PDF (149.9 KB)
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